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9601
[ "We", "compared", "glucocorticoid", "receptor", "binding", "characteristics", "and", "glucocorticoid", "responsiveness", "of", "human", "mononuclear", "leukocytes", "(", "HML", ")", "from", "hypertensive", "patients", "and", "matched", "normotensive", "volunteers", "." ]
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9602
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9603
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9604
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[ "We", "measured", "plasma", "hormones", "by", "radioimmunoassay", "." ]
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9606
[ "Kd", "values", "(", "mean+/-SE", ")", "for", "cortisol", "in", "HML", "of", "hypertensive", "patients", "were", "higher", "than", "in", "control", "subjects", "(", "24.6+/-2.4", "versus", "17.5+/-1.7", "nmol/L", ",", "P", "<", ".04", ")", "." ]
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9610
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9611
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9613
[ "Hence", ",", "decreased", "sensitivity", "to", "cortisol", "is", "associated", "with", "renin", "suppression", "." ]
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9614
[ "This", "hypothesis", "is", "supported", "by", "evidence", "of", "hypertension", "and", "low", "renin", "activity", ",", "which", "others", "have", "described", "in", "patients", "with", "primary", "glucocorticoid", "resistance", "due", "to", "mutations", "of", "the", "glucocorticoid", "receptor", "." ]
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9624
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9625
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9626
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9628
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9629
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9630
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9631
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9633
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