Datasets:
siddharthtumre
/
Revised-JNLPBA

Dataset card Data Studio Files Community
1
id
stringlengths
1
5
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sequence
ner_tags
sequence
13101
[ "Expression", "of", "surface", "markers", ",", "intracytoplasmic", "content", "of", "cytokines", "cell", "cycle", "analysis", "after", "BrdU", "incorporation", "and", "DNA", "staining", "with", "propidium", "iodide", "were", "studied", "by", "flow", "cytometry", "." ]
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13102
[ "Percentage", "of", "apoptotic", "cells", "was", "determined", "by", "in-situ", "labelling", "of", "DNA", "strand", "breaks", "." ]
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13103
[ "No", "significative", "changes", "in", "EBV", "latency", "nor", "in", "cell", "surface", "marker", "expression", "was", "found", "." ]
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13104
[ "In", "contrast", ",", "intracytoplasmic", "TNFalpha", "levels", "were", "strongly", "reduced", "in", "transfected", "clones", "." ]
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13105
[ "Furthermore", ",", "30", "%", "of", "IkappaBalpha", "transfected", "cells", "were", "apoptotic", "after", "8", "h", "of", "TNFalpha", "treatment", "." ]
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13106
[ "This", "correlated", "with", "a", "strong", "reduction", "of", "BrdU", "incorporation", "after", "24", "h", "of", "TNFalpha", "treatment", "." ]
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13107
[ "No", "effect", "was", "seen", "with", "non", "transfected", "cells", "or", "with", "cells", "transfected", "with", "a", "control", "plasmid", "." ]
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13108
[ "Our", "results", "suggest", "that", "the", "TNFalpha", "gene", "could", "be", "one", "of", "the", "targets", "of", "NF-kappaB", "in", "EBV", "infected", "cells", "and", "that", "NF-kappaB", "protects", "EBV-infected", "cells", "from", "apoptosis", "induced", "by", "TNFalpha", ",", "which", "may", "favour", "the", "proliferative", "effect", "of", "this", "cytokine", "." ]
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13109
[ "Seminoma", "in", "a", "postmenopausal", "woman", "with", "a", "Y", ";", "15", "translocation", "in", "peripheral", "blood", "lymphocytes", "and", "a", "t", "(", "Y", ";", "15", ")", "/45", ",", "X", "Turner", "mosaic", "pattern", "in", "skin", "fibroblasts", "." ]
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13110
[ "We", "report", "an", "unusual", "case", "of", "a", "55", "year", "old", "Japanese", "woman", "with", "a", "seminoma", "but", "relatively", "normal", "menses", "." ]
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13111
[ "The", "patient", "was", "a", "phenotypic", "female", "with", "late", "onset", "menarche", "(", "18", "years", "of", "age", ")", ",", "who", "was", "amenorrhoeic", "for", "the", "first", "year", ",", "followed", "by", "menses", "of", "one", "to", "three", "days", "'", "slight", "flow", "with", "dysmenorrhoea", ",", "but", "an", "otherwise", "normal", "menstrual", "history", "." ]
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13112
[ "A", "typical", "seminoma", "was", "removed", "from", "the", "left", "adnexal", "region", "and", "an", "immature", "testis", "was", "identified", "separately", "as", "an", "associated", "right", "adnexal", "mass", "." ]
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13113
[ "Repeated", "karyotypic", "studies", "on", "peripheral", "blood", "lymphocyte", "cultures", "showed", "only", "46", ",", "X", ",", "-Y", ",", "t", "(", "Y", ";", "15", ")", "(", "q12", ";", "p13", ")", "." ]
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13114
[ "Cytogenetic", "examination", "of", "the", "patient", "'s", "younger", "brother", ",", "who", "had", "fathered", "three", "healthy", "children", ",", "showed", "an", "identical", "karyotype", "." ]
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13115
[ "Mosaicism", "of", "46", ",", "X", ",", "-Y", ",", "t", "(", "Y", ";", "15", ")", "(", "q12", ";", "p13", ")", "/45", ",", "X", "cell", "lines", "was", "found", "in", "skin", "samples", "from", "the", "patient", "'s", "elbow", "and", "genital", "regions", ",", "although", "there", "were", "no", "clinical", "stigmata", "of", "Turner", "syndrome", "." ]
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13116
[ "An", "androgen", "receptor", "binding", "assay", "of", "cultured", "genital", "skin", "fibroblasts", "was", "negative", "." ]
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13117
[ "Molecular", "analysis", "using", "Southern", "blot", "hybridisation", ",", "PCR", ",", "and", "direct", "DNA", "sequencing", "showed", "that", "neither", "the", "patient", "nor", "her", "brother", "had", "a", "detectable", "deletion", "or", "other", "abnormalities", "of", "Y", "chromosome", "sequences", ",", "including", "the", "SRY", "(", "sex", "determining", "region", "of", "the", "Y", "chromosome", ")", "gene", "sequence", "." ]
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13118
[ "These", "findings", "suggest", "that", "Turner", "mosaicism", "of", "the", "45", ",", "X", "cell", "line", "may", "have", "contributed", "to", "this", "atypical", "presentation", "in", "an", "XY", "female", ",", "although", "we", "can", "not", "exclude", "abnormalities", "of", "other", "genes", "related", "to", "sex", "differentiation", "." ]
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13119
[ "Potent", "inhibition", "of", "HIV", "type", "1", "replication", "by", "an", "antiinflammatory", "alkaloid", ",", "cepharanthine", ",", "in", "chronically", "infected", "monocytic", "cells", "." ]
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13120
[ "Cepharanthine", "is", "a", "biscoclaurine", "alkaloid", "isolated", "from", "Stephania", "cepharantha", "Hayata", "and", "has", "been", "shown", "to", "have", "antiinflammatory", ",", "antiallergic", ",", "and", "immunomodulatory", "activities", "in", "vivo", "." ]
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13121
[ "As", "several", "inflammatory", "cytokines", "and", "oxidative", "stresses", "are", "involved", "in", "the", "pathogenesis", "of", "HIV-1", "infection", ",", "we", "investigated", "the", "inhibitory", "effects", "of", "cepharanthine", "on", "tumor", "necrosis", "factor", "alpha", "(", "TNF-alpha", ")", "-", "and", "phorbol", "12-myristate", "13-acetate", "(", "PMA", ")", "-induced", "HIV-1", "replication", "in", "chronically", "infected", "cell", "lines", "." ]
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13122
[ "Two", "chronically", "HIV-1-infected", "cell", "lines", ",", "U1", "(", "monocytic", ")", "and", "ACH-2", "(", "T", "lymphocytic", ")", ",", "were", "stimulated", "with", "TNF-alpha", "or", "PMA", "and", "cultured", "in", "the", "presence", "of", "various", "concentrations", "of", "the", "compound", "." ]
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13123
[ "HIV-1", "replication", "was", "determined", "by", "p24", "antigen", "level", "." ]
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13124
[ "The", "inhibitory", "effects", "of", "cepharanthine", "on", "HIV-1", "long", "terminal", "repeat", "(", "LTR", ")", "-driven", "gene", "expression", "and", "nuclear", "factor", "kappaB", "(", "NF-kappaB", ")", "activation", "were", "also", "examined", "." ]
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13125
[ "Cepharanthine", "dose", "dependently", "inhibited", "HIV-1", "replication", "in", "TNF-alpha-", "and", "PMA-stimulated", "U1", "cells", "but", "not", "in", "ACH-2", "cells", "." ]
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13126
[ "Its", "50", "%", "effective", "and", "cytotoxic", "concentrations", "were", "0.016", "and", "2.2", "microg/ml", "in", "PMA-stimulated", "U1", "cells", ",", "respectively", "." ]
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13127
[ "Cepharanthine", "was", "found", "to", "suppress", "HIV-1", "LTR", "-driven", "gene", "expression", "through", "the", "inhibition", "of", "NF-kappaB", "activation", "." ]
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13128
[ "These", "results", "indicate", "that", "cepharanthine", "is", "a", "highly", "potent", "inhibitor", "of", "HIV-1", "replication", "in", "a", "chronically", "infected", "monocytic", "cell", "line", "." ]
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13129
[ "Since", "biscoclaurine", "alkaloids", ",", "containing", "cepharanthine", "as", "a", "major", "component", ",", "are", "widely", "used", "for", "the", "treatment", "of", "patients", "with", "various", "inflammatory", "diseases", "in", "Japan", ",", "cepharanthine", "should", "be", "further", "pursued", "for", "its", "chemotherapeutic", "potential", "in", "HIV-1-infected", "patients", "." ]
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13130
[ "NF-kappaB", "only", "partially", "mediates", "Epstein-Barr", "virus", "latent", "membrane", "protein", "1", "activation", "of", "B", "cells", "." ]
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13131
[ "The", "latent", "membrane", "protein", "1", "(", "LMP1", ")", "of", "Epstein-Barr", "virus", "(", "EBV", ")", "is", "required", "for", "EBV-induced", "immortalization", "of", "human", "B", "cells", "and", "causes", "tumorigenic", "transformation", "of", "cell", "lines", "." ]
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13132
[ "LMP1", "expression", "induces", "phenotypic", "changes", "resembling", "B", "cell", "activation", ",", "such", "as", "cell", "size", "increase", "and", "up-regulation", "of", "cell", "surface", "activation", "markers", "." ]
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13133
[ "LMP1", "contains", "two", "domains", "that", "activate", "the", "transcription", "factor", "NF-kappaB", ",", "one", "through", "interactions", "with", "TRAF", "proteins", "and", "the", "other", "with", "the", "TRADD", "protein", "." ]
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13134
[ "The", "purpose", "of", "the", "present", "study", "was", "to", "investigate", "the", "importance", "of", "NF-kappaB", "induction", "in", "the", "up-regulation", "of", "the", "B", "cell", "activation", "markers", "ICAM-1", "and", "CD71", "by", "LMP1", "." ]
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13135
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13136
[ "ICAM-1", "and", "CD71", "are", "nevertheless", "up-regulated", "by", "LMP1", "in", "primary", "B", "cells", "and", "cell", "lines", "expressing", "the", "dominant", "IkappaB", "." ]
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13137
[ "Furthermore", ",", "LMP1", "-induced", "cell", "size", "increase", "of", "primary", "B", "cells", "was", "unaffected", "by", "IkappaB", "expression", "." ]
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13138
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13139
[ "Models", "of", "lineage", "switching", "in", "hematopoietic", "development", ":", "a", "new", "myeloid-committed", "eosinophil", "cell", "line", "(", "YJ", ")", "demonstrates", "trilineage", "potential", "." ]
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13140
[ "A", "new", "human", "leukemia", "cell", "line", "with", "an", "eosinophilic", "phenotype", ",", "designated", "YJ", ",", "was", "established", "from", "the", "peripheral", "blood", "cells", "of", "a", "patient", "with", "chronic", "myelomonocytic", "leukemia", "(", "CMMoL", ")", "with", "eosinophilia", "." ]
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13141
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13142
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13143
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13144
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13145
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13146
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13147
[ "YJ", "cells", "treated", "in", "vitro", "with", "2", "microM", "RA", "differentiated", "into", "metamyelocytes", "and", "band", "neutrophils", ",", "and", "increased", "the", "number", "of", "nitroblue", "tetrazolium", "(", "NBT", ")", "-positive", "cells", "and", "increased", "gp91phox", "mRNA", "expression", "." ]
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13148
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13149
[ "The", "expression", "of", "genes", "for", "transcription", "factors", "involved", "in", "myeloid", "differentiation", "was", "evaluated", "by", "Northern", "blot", "analysis", "." ]
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13150
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13151
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13152
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13153
[ "Interleukin-6", "production", "in", "hemorrhagic", "shock", "is", "accompanied", "by", "neutrophil", "recruitment", "and", "lung", "injury", "." ]
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13154
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13179
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