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6,800
…when inhibition is quantified as the per cent suppression of an MEP, a small test response of 0.3 mV is less susceptible to SICI at 2.5 ms than a larger response (Sanger et al. 2001; Roshan et al. 2003) because SICI depends on the inhibition of late I-waves that are only recruited in larger MEPs.
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method
6,801
This is consistent with prior research that considers individuals as navigating a turbulent career environment, forcing them to draw from multiple sources of developmental support ( Higgins and Kram, 2001 ).
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background
6,802
Gouveia and Martins [7] reviewed exact and lower bounding schemes, including earlier works of Gavish [4, 5], the branch-and-bound algorithm of Malik and Yu [10], the Lagrangean relaxation approach of Gouveia [6], and the cutting plane method of Hall [9].
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background
6,803
In state of the art schemes [16,5], a warrant ω is either the concatenation of all permitted messages or an abstract description of the message space for which signing is being delegated, together with a certificate, which is a signature on ω (and typically other values including the proxy’s identity and public key), under the delegator’s private signing key.
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background
6,804
Along this line of thought, RBL cells display both polarized and receptor-stimulated endocytic recycling (57, 58), and we show in this paper that they also express Rab13, Rab17, Rab20, and Rab25, which are all implicated in polarized transport in epithelial cells.
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background
6,805
Similar results in vertebrates were found in a study of fries of the fish Clarias gariepinus Burchell, 1822 (Siluriformes: Clariidae) in which the effects of hydrocarbons (crude oil, benzene, toluene, and xylene) were examined after 4 days of exposure (Otitoloju & Olagoke 2011).
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result
6,806
Besides, we also notice that some existing approaches [8, 9] can be used indirectly to mine maximal frequent sequences under differential privacy.
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method
6,807
This indicates that the upregulation of TGF-b1 by ANG II is enhanced in the obstructed kidney, an effect that occurs in the face of normalization of receptor expression after 3 days of UUO (48).
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background
6,808
We targeted the right auditory cortex because previous studies reported selectively right-sided activity in the superior temporal gyrus during timing tasks (e.g., Coull et al. 2004; Rao et al. 1997; Coull et al. 2008).
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method
6,809
…hippocampus for episodic encoding and retrieval processes in healthy young subjects was initially proposed as part of the HIPER model, with the anterior part of the hippocampus being preferentially involved in encoding, and retrieval mainly depending on its posterior portion (Lepage et al., 1998).
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method
6,810
For example, we have shown that a depressive mood state and poor quality of life are less likely in elderly individuals who meet empirical minimum standards of habitual physical activity: >4,000 steps/day or >5 min/day at an intensity ≥3 metabolic equivalents (METs; Yasunaga et al., 2006; Yoshiuchi et al., 2006).
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background
6,811
Similar results have been reported regarding D. dadantii 3937 by Yi et al. (2010) who showed that the c-di-GMP turnover was mediated by GGDEF and EAL domain proteins in D. dadantii 3937.
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result
6,812
By contrast, Hanlon et al. (1998) showed that higher serum cholesterol reduced the risk of hospitalization in this population.
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result
6,813
These results support findings in the literature that describe deficits in explicit processing of dynamic emotional expression in individuals with ASD (Back et al., 2007; Lindner & RoseÃÅn, 2006), but preserved lipreading skills (De Gelder et al., 1991; Gepner et al., 2001).
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result
6,814
We previously reported that this pattern is the result of specific expression of Arpp/Ankrd2 in type 1 myofibers (Tsukamoto et al. 2002).
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background
6,815
have estimated that following clinical guidelines, about 27% of African Americans with HF in the US are eligible to receive FDC-ISDN/HYD, but they have observed that compliance with these guidelines is poor [18].
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background
6,816
According to different authors, anxiety seems to be one of the fundamental factors that regulate EDA [Geer, 1966; Corah and Pantera, 1968; West et al., 1983].
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background
6,817
To derive the expressions, we follow the similar notation as proposed in [3].
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method
6,818
In particular, it provides some information as to why SM/J mice may show diminished glucose tolerance in comparison to the LG/J strain [24] on a high fat diet.
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background
6,819
…Spanish, as spoken in Madrid (Estebas-Vilaplana, 2006; Estebas-Vilaplana & Prieto, 2007), Salamanca (de la Mota, 2005), and Majorca (Simonet & Torreira, 2005; Simonet, 2006), and on Central Catalan as spoken in Barcelona (Estebas-Vilaplana, 2003; Estebas-Vilaplana & Prieto, 2007; Prieto, 2006).
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background
6,820
The authors of [3] study the problem of Early Application Identification and show that it is enough to know the length of the first four or five packets to
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background
6,821
…inactivation (Charlton et al., 1982; Chaudhuri et al., 2005; Forsythe et al., 1998; Xu and Wu, 2005) and vesicle depletion (Custer et al., 2006; Pieribone et al., 1995; Schneggenburger et al., 2002; Xu and Wu, 2005) have varying dependence on the frequency of stimulation at different synapses,…
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background
6,822
In previous time-series studies, many lag structures were considered in multiple models, and the authors presented only the statistically significant results (Schwartz et al., 1997, 2000).
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background
6,823
In this sense, oligodendrogliomas can show similar pathological findings to liponeurocytoma [5, 6, 12, 18, 21, 24, 26], although Olig2 immunohistochemistry is reported to show a high possibility of positive results in oligodendroglioma, while neurocytomas are mostly negative [15, 20, 23].
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background
6,824
Both the alleviation of fluid overload [3] as well as the provision of this necessary volume in the form of medications improve outcomes and mortality risk.
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background
6,825
Work with non-neuronal cells has suggested that BCL-xL regulates the flux of metabolites across the outer mitochondrial membrane to facilitate transport of ATP into the cytosol after a death stimulus (Vander Heiden et al., 2000, 2001).
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background
6,826
We have added the affordances to the definitions by hand, but we will look at ways to automate this, either based on semantic annotations provided with the CAD files as in [15], or possibly some geometric reasoning on part features.
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method
6,827
To determine this canonical set of values, the parameters from the mathematical model of the leech HN neurons were used as a starting point because the silicon neurons were based on this mathematical model [54].
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method
6,828
In [103], a gamma, X-ray, and high energy proton radiationtolerant SPAD has been developed for space applications.
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background
6,829
Interestingly, within such a time interval, AMPAR translocation seems to occur predominantly between an intracellular somatic pool and extrasynaptic somatic sites (Adesnik et al., 2005).
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background
6,830
This section contains a generalisation of the basic results on multifractal products of stochastic processes developed in Kahane (1985), Kahane (1987) and Mannersalo et al (2002).
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background
6,831
Cold can activate sympathetic nerve system (SNS) to excrete norepinephrine, and then the BAT, which is rich in sympathetic nerve terminals, will produce more heat [11].
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background
6,832
We use 3 standard MLC benchmarks, as used by other recent approaches (Belanger & McCallum 2016; Gygli et al. 2017; Amos & Kolter 2017): Bibtex, Delicious, and Bookmarks.
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method
6,833
The admission assessment included determining the risk factors for cerebral infarction,13,14 clinical ischemic stroke category (National Institute of Neurological Disorders and Stroke1), and disease severity using the National Institutes of Health Stroke Scale.15 545 Abbreviations AF = Atrial fibrillation LAA = Left atrial appendage LAA eV = LAA emptying flow velocity LAD = Left atrial dimension LAWV = LAA peak wall velocity ROC = Receiver operating characteristic SEC = Spontaneous echocardiographic contrast TEE = Transesophageal echocardiography TTE = Transthoracic echocardiography We defined patients who had no histories of AF and no documented AF on continuous electrocardiographic monitoring during hospitalization as the sinus rhythm group, patients who had histories of AF before admission and/or continuously documented AF on continuous electrocardiographic monitoring during hospitalization as having chronic AF, and patients who had AF at admission and recovered to normal sinus rhythm during hospitalization and/or showed sinus rhythm at admission and documented transient AF on continuous electrocardiographic monitoring during hospitalization as having paroxysmal AF.
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method
6,834
…Accession P21334), al-2 (UniProt Accession P37295) and al-3 (UniProt Accession P24322) were used to search the genomic sequence of P. anserina [Espagne et al. 2008), published at http://www.genoscope.cns.fr/externe/ English/Projets/Projet_GA/GA.html (P. anserina sequencing consortium)] for…
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method
6,835
The review protocol describes all steps performed during the review, reduces risk of bias, and increases its rigor, transparency, and repeatability [17].
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background
6,836
In this paper, W , is an intermediate logic,resembling first order logic, that uses the meta-data gleaned from WordNet, and is used as an intermediary stepping logic that can be converted into another logic, such as a first order logic.
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method
6,837
We demonstrate that the average amplitudes of contralateral PBR (cPBR) and ipsilateral NBR (iNBR) were negatively correlated as previously reported and thought to result from increased ipsilateral inhibition occurring concurrently with increased contralateral excitation (Klingner et al., 2010; Shmuel et al., 2002).
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result
6,838
18 De Cocker, 2011 [16] Belgium 1 1566 CABG, valve, combined, and other Prolonged > 2, 5, 7 days & continuous Prediction model
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background
6,839
1998), to provide great £exibility in testing evolutionary hypotheses (Huelsenbeck & Rannala 1997), and simply to give excellent results in the inference of evolutionary relationships (Kuhner & Felsenstein 1994; Huelsenbeck 1995). Constraints imposed by computational complexity are becoming less restrictive as computers improve. Given the recognition of phylogenetic inference as being inherently statistical in nature, it is surprising that so little attention has been paid to experimental design. A number of topics of relevance to experimental design in phylogenetics have been discussed previously. There is something of a folklore surrounding the choice of genes or other genomic regions for investigating particular evolutionary questions, but almost no published quantitative results. It is widely accepted that sequences that have undergone very little evolutionary change since their divergence from a common ancestor, through low substitution rates or short evolutionary times, will exhibit too few di¡erences to contain useful evolutionary information. Equally, sequences that have undergone very large amounts of change (high rates or long times) become `saturated' with changes and no evolutionary signal is detectable amid the noise. Consequently, a happy medium is expected at some intermediate level of sequence divergence, but the àsymptotic' results (for extreme high and low levels of divergence) give no clue as to where this lies. Although there is considerable experience with particular genes and organisms (see Hillis et al. (1996, pp. 336^339) for an extensive list of studies), where comparisons among genes have been made they tend to be evaluated empirically by the congruence of the results obtained among themselves and with researchers'a priori expectations. In addition, a large laboratory e¡ort is needed before even these qualitative conclusions can be reached. The methods introduced in this paper can quantify the e¡ects of varying levels of divergence. They con¢rm the belief that intermediate levels of...
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background
6,840
…acid peptide domain known as the homeodomain (McGinnis et al., 1984a,b; Laughon and Scott, 1984), a peptide motif conferring sequence-specific DNA binding ability to the homeoproteins (Laughon and Scott, 1984; Desplan et al., 1985; Beachy et al., 1988; Müller et al., 1988; Ekker et al., 1991).
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background
6,841
Studies in other sub-Saharan African countries also showed that rural women had significantly higher unmet need compared to urban women (21, 26, 27, 31).
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background
6,842
2015) as the weight initialization method and train our network using Adam (Kingma and Ba 2014) with a minibatch size of 64.
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method
6,843
To visualize CSE1-GFP and RFP-VPS-52 localization, the strains were grown on Vogel’s MM plates overnight and squares of 1 cm were excised and examined in the same confocal microscope explained above using the 488-nm laser for GFP and 563 nm laser for RFP.
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method
6,844
Based on previous studies, bothmGluR1 andmGluR5 were very important for the regulation of pyramidal cell excitability (Mannaioni et al., 2001; Ireland and Abraham, 2002).
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result
6,845
In the context of the SPIN model checker [24], AI Planning heuristic search methods have been adapted to SPIN [9, 10], and compilations from Promela to AI Planning languages have been designed [8].
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method
6,846
A longer pulse or a longer rising/falling time will increase the interaction of the light photons and acoustic phonons and lead to a worse spatial resolution along the fiber [1].
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background
6,847
Aberrant mammalian GPCR activity has been directly linked to such maladies as blindness, asthma, heart disease, obesity, and cancer [13,14].
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background
6,848
Based on previous studies, each intervention could be assumed to increase the breastfeeding rate and correspondingly reduce the incidence of rotavirus-diarrhea [1,3,10-12].
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method
6,849
ethnic minorities and an often difficult relationship between service users and mental health services (Broome et al. 2005).
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background
6,850
FGF23 induces hypertrophic growth of cardiac myocytes in vitro and LVH in rodents through a direct FGFR-dependent mechanism, but independently of a-klotho, which is not expressed in cardiac myocytes (Faul et al., 2011).
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background
6,851
Importantly, most repeated sequences that extend >20 bp actually extend over at least 100 bp (20).
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background
6,852
The 5 2.3 kb enhancer region (chr2: 19351717-19354014) was cloned into the BgEGFP reporter vector (Lumpkin et al., 2003) to generate 2.3Ptf1a-GFP or a nuclear lacZ reporter gene with the minimal promoter of the rat Ela1 gene to generate 2.3Ptf1a-lacZ (Masui et al., 2008).
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method
6,853
An aborted process cancels its pending requests and releases the resources it held [15].
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background
6,854
…information, studies in awake behaving animals have shown only changes in the firing rate of Purkinje cells to be correlated with movementrelated parameters (Lisberger and Fuchs 1978; Mano and Yamamoto 1980; Medina and Lisberger 2007, 2008; Pasalar et al. 2006; Thach 1970; Yamamoto et al. 2007).
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background
6,855
…of highly active antiretroviral therapy (HAART) as the standard of care, with six additional studies (Baigis et al., 2002; Lox et al., 1996; MacArthur et al., 1993; Perna et al., 1999; Stringer, Berezovskaya, O’Brien, Beck, & Casaburi, 1998; Terry et al., 2006) including subjects on some…
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background
6,856
Invasive species can alter successional patterns, mutualistic relationships, community dynamics, ecosystem function and resource distributions (Mooney & Cleland 2001).
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background
6,857
Race-related beliefs shape perceptions of White disadvantage and , doi:10.1016/j.obhdp.2010.11.011 are a result of efforts to protect the outcomes of one’s in-group (e.g., Lowery et al., 2006), rather than an objection to cultural norms of meritocracy.
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background
6,858
These concentrations of fluoxetine and propranolol were chosen in order to represent high environmental concentrations (based on surface water, wastewater effluent, and predicted environmental concentrations) up to those shown to result in effects on fish [26–29], or where the fish plasma model [30] would predict concentrations above human therapeutic levels (Cmax).
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background
6,859
(Ig)–like domains and whose cytoplasmic region contains immunoreceptor tyrosine-based inhibition motifs that mediate the binding and activation of the protein tyrosine phosphatases SHP-1 and SHP-2.(19,20) Tyrosine phosphorylation of SIRPα is triggered by various growth factors and cytokines as well as by integrin-mediated cell adhesion to extracellular matrix proteins.
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background
6,860
In [36], the LBP is adopted to describe the neighboring relationship not only in image space, but also in the responses by convolving multi-scale and multiorientation Gabor filters.
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method
6,861
Stability is often reached after only five or so convergent interviews [50].
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background
6,862
…projection neurons [medium spiny neurons (MSNs)] increase their firing rate following local application of GABA antagonists (Bernardi et al., 1976; Nisenbaum and Berger, 1992; Kita, 1996; Darbin and Wichmann, 2008), which should, in theory, increase inhibition to the GPe via the indirect pathway.
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background
6,863
For controls, all three primer pairs were tested in the second-round PCR. Primers specific to Botrytis, Cladosporium and Fusarium (Table 1) were designed based on the ITS sequences from our previous publication (Shipunov et al., 2008).
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method
6,864
The EPIYA motifs have been classified into four types, A, B, C and D (Higashi et al., 2002a), based on the amino acid sequences following each type and all types can be phosphorylated in vitro.
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method
6,865
The processes of tessera formation and their relationship to crustal plateaus have been explored in an extensive body of work [e.g., Head and Crumpler, 1987; Herrick and Phillips, 1990; Bindschadler and Head, 1991; Bindschadler et al., 1992a, 1992b; Bindschadler, 1995; Grimm, 1994; Brown and Grimm, 1997; Hansen and Willis, 1996, 1998; Ivanov and Head, 1996; Pritchard et al., 1997; Gilmore et al., 1997, 1998; Head and Basilevsky, 1998; Phillips and Hansen, 1994, 1998; Hansen et al., 1997, 1999, 2000; Ghent and Hansen, 1999; Banks and Hansen, 2000].
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background
6,866
AML is characterized by the aberrant juxtaposition of the oncogene ecotropic viral integration site 1 (EVI1), with regulatory elements of ribophorin 1 (RPN1), resulting in overexpression of EVI1 (Buonamici et al., 2003).
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background
6,867
Supporting this theory, it has been shown that use of non-steroidal anti-inflammatory drugs (NSAIDs), particularly ibuprofen, was associated with a lower risk for PD (Chen et al., 2003; Gao et al., 2011).
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method
6,868
Beneficial fungal secondary metabolites have a wide range of applications, including antibiotics (penicillin and cephalosporin [52]), immunosuppressants (cyclosporins [140]), cholesterol-lowering drugs (statins [115]), angiogenesis inhibitors (fumagillin derivatives and pseurotin derivatives [5, 15]), anti-osteoporosis agents (orsellinic acid derivatives F-9557 A and B [23]), anti-migraine and hypertension-lowering medications (ergot alkaloids [73]), plant growth hormones (gibberellins [27]) and food additives (carotenoids [7]).
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background
6,869
Except for some parameter values, the game studied by Schneider and Kube is similar to the individual wage treatment in Abeler et al. (2010).
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result
6,870
The majority of our findings are in line with prior studies such as those dealing with the adoption of mobile technology (Kim and Garrison, 2009; Lee and Park, 2008), with two notable exceptions.
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result
6,871
Interestingly, the HDAC4- Dach2-myogenin transcriptional axis is also required for full induction of the ubiquitin E3 ligases MuRF1 and atrogin-1 that promote atrophy (Cohen et al., 2007; Macpherson et al., 2011; Moresi et al., 2010).
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background
6,872
While targets are expressed in Domain Notation[9] in the PONDER framework , we treat the domain name for targets as the name to be mapped to managed entities in a J2EE application server.
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method
6,873
Similarly, the typical primate pattern of males being larger than females may have been selected against through generations of large, aggressive males dying during periods of energetic stress (Wright 1999).
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background
6,874
If a cerebral vasculitis of autoimmune origin is suspected, there has to be first a pretest verification: predominantly females, young, no previous history of cardiovascular disease, focal or multiple lesions evidenced in a brain MRI or CT [17].
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background
6,875
Finally, the role of MMPs in fibrogenesis is complicated by their apparent role in both the resolution of liver fibrosis, in which MMPs promote ECM degradation, and their role in clearance of fibroblastic HSCs (9, 22, 23, 41).
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background
6,876
We quantified the maximum C biomass that could be stored per unit area using two methods: (1) 90th-percentile QR and (2) OLS regressions (Supplementary Methods).
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method
6,877
4, December, 2013 translocation of these enzymes to the plasma membrane and/or other membrane (Littler et al., 2006; CorbalánGarcía & Gómez-Fernández, 2010).
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background
6,878
A subset of patients (n = 74) were screened for the multiple endocrine neoplasia 1 (MEN1) gene using direct bidirectional sequencing and multiplex ligation-dependent probe amplification.(19) In addition, 36 patients had stored urine samples collected before undergoing TSS; in these samples, spot urine calcium and creatinine were measured using the Dimension Clinical Chemistry system (Siemens Healthcare Diagnostics, Tarrytown, New York).
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method
6,879
[3, 10] In addition, patients with lower economic status have even less perception of glaucoma.
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background
6,880
Construct validity of the CORE as a measure of melancholia Vares et al. (2015) investigated the underlying dimensions of depression comparing instruments that measure depression from different perspectives – namely, a self-report symptomatic scale (Beck Depression Inventory), a clinician-rated…
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background
6,881
However, this ignores the biological function of a negative emotional reaction such as a pain reaction, since these have evolved to protect an individuals overall welfare (Ohl, 2011).
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background
6,882
with the saturated b-wave amplitude Vmax, the flash intensity K required for semi-saturation as a measure of retinal sensitivity, and the slope related exponent n [27].
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background
6,883
As reproduction appears the key trait maximizing fitness (Viblanc et al. 2010), we predicted that greater allocations into reproduction should be made in the presence of greater number of kin, either due to a positive effect of kin numbers on energy income, or if more female kin provide a safer…
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background
6,884
We have compared gluconeogenic measurements using our method based on average deuterium enrichment with those of the C-5 HMT method [10] under conditions when fractional gluconeogenesis is low, intermediate and high.
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method
6,885
We assessed opposition to Arab immigration by asking participants to assign a limited number of immigrant visas to various groups (e.g., East Asians, Arabs, Eastern Europeans), and then taking the reverse-scored proportion of visas assigned to Arabs (Kteily et al., 2015).
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background
6,886
Nuclear localization of PTOV1 is required for the stimulation of cell proliferation (Santamaria et al. 2005; Santamaria et al. 2003).
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background
6,887
As such, direct analysis of wine by ICP-MS can affect plasma conditions and sample transport thus causing variations in signal stability and intensity [9,10].
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background
6,888
…3 e (a)s ) assumed asymptotically flat (therefore noncompact) at spatial infinity and geodesically complete [so that, due to the Hopf-Rinow theorem [39], every two points of Σ τ may be connected by a minimizing geodesic segment and there exists a point p ∈ Σ τ from which Σ τ is geodesically…
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background
6,889
The maintenance of close nest burrows (King 1989b; Viblanc et al. 2010), greater tolerance (King 1989a; V.A. Viblanc, C. Pasquaretta, C. Sueur, R. Boonstra & F.S. Dobson, unpublished results) and less infanticide (Dobson 1990; Stevens 1998) between kin during this highly energy constraining period…
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background
6,890
We optimize using RMSProp [11] and Adam [12] gradient descent solvers, which both obtain relatively similar results.
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result
6,891
The loading values are arranged in such a way that the changes of the properties of fluorophores can easily be caught throughout the cooking kinetic of meat samples (Boubellouta and Dufour 2008).
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background
6,892
However, increased activation and connectivity in PCC have been exploited in patients with epilepsy.([14]) One possible interpretation for the paradox was that there might be a compensatory mechanism that occurs in the resting state results.
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background
6,893
The result is consistent with the suggestion by Furuya et al. (1994; 2000) that the contribution of the Rydberg states to CH+3 is comparable to that of the (1t2) ‚àí1 state.
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result
6,894
TSSs of HERG1b, KCNQ1a, and KCNQ1b genes were determined with Ambion’s RNA-Ready cDNA Human Heart RNA Ligase-Mediated Rapid Amplification of cDNA Ends (5 -RACE) kit, as previously described (15).
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method
6,895
We screened for potential TF binding sites using STAMP [59], with the motifs’ position weight matrices (PWMs) retrieved from the TRANSFAC database [60].
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method
6,896
These concentrations were selected to approximate the levels of contamination that are predicted to occur in a clinical setting (Benjamin & Wagner, 2007).
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background
6,897
Maintaining a negative DCm induces Ca 21 accumulation in mitochondria (11, 12, 19).
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background
6,898
In addition, the discriminative power of the selection criteria used for a UK AS cohort (Selvadurai et al, 2013) and the effect of the number of biopsy cores (Ochiai et al, 2005) containing cancer were evaluated.
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background
6,899
In time-to-event analysis, Cox proportional hazards regression models that controlled for study design were used to estimate crude and adjusted hazard ratios (AHR) and 95% confidence intervals (CI) for covariates of interest [34].
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method