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ovulation and amenorrhea.(16) Environmental compounds that possess steroidogenic(17) or anti-steroidogenic(18) activity affect onset of puberty and reproductive function in adulthood.
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6,601
Primary antibodies were incubated for 1 hour and secondary antibodies for 30 minutes (7, 8).
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6,602
Furthermore, PRRs are also involved in the control of hypocotyl elongation and flowering time (Makino et al., 2002; Matsushika et al., 2002, 2007b; Sato et al., 2002; Kaczorowski and Quail, 2003; Murakami et al., 2004).
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6,603
increasing proportion of cells recorded in the sub-G1 phase with increasing concentrations of arachidonic acid (Dymkowska et al., 2006).
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6,604
The stability of these societies depends on individuals’ decisions governing group membership, which are intimately related to individuals’ costs and benefits of living in the group (Danchin and Wagner 1997; Clutton-Brock et al. 1998; Buston 2003a).
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6,605
For example, it has been shown that auditory sources result in broad activation patterns in the mid sagittal plane (Van Veen, 1997; Quraan and Cheyne, 2008; Quraan and Cheyne, 2010).
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6,606
2005) without reservation and none of the features invoked by Jaeger et al. (1999) have been reassessed or challenged in detail, with the exception of the character analysis by Gunnell and Miller (2001). This defining list of traits overlaps considerably the battery of features long used to support the adapid-anthropoid hypothesis and now regarded as likely convergences (e.g., Rosenberger et al. 1985). Kay et al. (2004) also added to the basic argument of Jaeger et al.
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6,607
We identified three major categories of barriers that, if resolved, would facilitate HIT use: (1) lack of local patient-level clinical data in VA-wide databases; (2) lack of VA-wide data in a standardized and analyzable format; (3) gaps in capture of clinical data in the EHR.
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6,608
Modeling phonology helps to keep both speech and ASL recognition tractable [25, 33], because there is only a small, limited number of phonemes, as opposed to the unlimited number of words and signs that can be built with them.
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6,609
It was shown that cathepsins are also present in other insects, e.g. Helicoverpa armigera (Yang et al., 2006) and Bombyx mori (Gui et al., 2006; Lee et al., 2009) and are involved in programmed cell death during metamorphosis.
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6,610
Combining more video clips improves the accuracy of the estimated data (Krosshaug and Bahr, 2005), and previous research also succeeded in motion reconstruction using somewhat blurry images (Koga et al., 2010).
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6,611
Bimodality has been described in the propulsion literature with the first peak, termed the impact spike, caused by the user forcefully contacting the pushrim at the beginning of the push phase (Robertson et al., 1996; Cooper et al., 1997).
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6,612
Furthermore, MMP-2 and -9 are expressed and secreted by astrocytes (Gottschall et al., 1995; Muir et al., 2002) and induced in the presence of A (Deb and Gottschall, 1996; Deb et al., 2003).
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6,613
For English, we used external embeddings of Dyer et al. (2015) learned using the structured skip n-gram approach of Ling et al. (2015), for Chinese, we used external embeddings produced with the neural language model of Bengio et al. (2003).
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6,614
A study by Rohwerder et al [35] investigated the degradation pathway of 2-hydroxyisobutyric acid (2-HIBA), an intermediate in the degradation pathway of MTBE.
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6,615
Titan and typical C. neoformans cells have different cell wall composition In vivo C. neoformans cells vary in size, from cells less than 3 μm in cell body diameter to cells more than 100 μm in diameter (Feldmesser et al., 2001; Okagaki et al., 2010; Zaragoza et al., 2010; Alanio et al., 2015).
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6,616
Sechium edule fruit extract contains non-phenolic alkaloids, saponins, sterols, triterpenoids (Salama et al. 1986) and glycosylated flavonoids (Siciliano et al. 2004) that confer its anti-inflammatory (Salama et al. 1987), antihypertensive (Gordon et al. 2000), antimicrobial (Ordo~nez et al. 2003),…
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6,617
Another important difference between the study by Hendriks et al. (2014) and the current study is that to elicit the Frontiers in Psychology | www.frontiersin.org 14 February 2018 | Volume 9 | Article 176 narratives, they showed their images one at a time (i.e., successive presentation in a…
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6,618
Artificial reefs made of various materials also provide a large shaded surface that A. coerulea planulae prefer (Holst & Jarms, 2007; Hoover & Purcell, 2009; Duarte et al., 2012).
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6,619
Although our results are in accordance with earlier studies giving prevalence rates between 4 and 8% using NIH criteria (Knochenhauer et al., 1998; DiamantiKandarakis et al., 1999; Michelmore et al., 1999; Asuncion et al., 2000; Azziz et al., 2004; March et al., 2010; Moran et al., 2010a,b; Sanchon et al., 2012), we found higher figures than previous studies using Rotterdam criteria (Chen et al.
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6,620
To analyze the statistical correlation between measures of the CT and schizophrenic psychopathology (measured by PANSS), we calculated a Spearman rank correlation within the first-episode schizophrenia (or SZ) patient group.
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6,621
…the antiapoptotic effects of endothelin in olfactory mucosa primary culture We had previously found that ET-1 could limit serum deprivationinduced apoptosis in OM primary culture, and gap junction uncoupling has been described to be neuroprotective in the central nervous system (Lin et al., 2003).
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[35] showed no significant improvement in swimming performance while wearing a drag suit for 5 weeks compared with the control group.
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, which is known as ge particle of the CA 54 [3, 12], should be rather considered as a complex object, since it is a kind of breather – arises from interaction between two simple particles represented by ERs .
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6,624
0 [113,114] was conducted using 100 random addition replicates and was based on a heuristic search using the tree bisection-reconnection (TBR) option; the best fit substitution model parameters were applied.
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6,625
…acids, are quantitatively taken up by intact cells or isolated mitochondria, the only relevant way of expressing their effective “concentration” is per mg protein of the biological material used rather than per volume of the incubation mixture (Dymkowska et al., 2006; Schönfeld & Wojtczak, 2007).
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6,626
The present results were also consistent with other reports suggesting that CCND1 plays an important role in the occurrence and development of OLP [36–38].
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6,627
…or live/dead assay (Bedaiwy et al., 2003, 2006; Martinez-Madrid et al., 2004; Arav et al., 2005; Courbiere et al., 2005, 2006; Imhof et al., 2006; Baudot et al., 2007), assays of apoptotic markers (Bedaiwy et al., 2003, 2006; Martinez-Madrid et al., 2007) and the cellcycle marker Ki67 as well as…
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6,628
To certain plant species, an explant origin of a species is not specific for the successful regeneration of transformed cells via Agrobacterium-mediated genetic vector (Sangwan et al., 1991a, b, 1992;Ducrocq et al., 1994).
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6,629
Energy landscapes and metabolic rates in these types of habitats have been assessed through modelling based on the chemical endmember composition of HFs and ambient SW (Tivey, 1995; McCollom and Shock, 1997; McCollom, 2000, 2007; Shock and Holland, 2004; Amend et al., 2011; LaRowe et al., 2014).
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6,630
Although activation was eventually attributed to the action of IFN-g and TNF-a (34), we postulated that some of the increased resistance may be induced directly by bacteria.
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6,631
Steps 3(c) to 3(f) can be done efficiently using techniques of Camenisch, Hohenberger, and Lysyanskaya [49].
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6,632
1 3 surgery after ESD, and those who were followed up but received no additional treatment after ESD [17].
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6,633
They are: Slope One, Regularized SVD, Improved Regularized SVD, SVD++, NMF, BPMF, RBM-CF, AutoRec and Mean Field.
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6,634
…disulfide bonds formed by conserved pairs of Cys residues not only play a role in maintaining the 3D protein structure but also contribute to the bioactivity of PRL, e.g., the mitogenic activity in NB2 cells (Luck et al., 1992) and osmoregulatory ability in urinary bladder (Doneen et al., 1979).
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6,635
Stimulation of cardiac respiration is known to decrease steady-state levels of NAD(P)H (35), but BDM did not affect the response of NAD(P)H to ADP (data not shown).
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6,636
Poultry, especially turkeys, are extremely sensitive to the toxic effects of AFB1 (Rawal et al., 2010a; Carnaghan et al., 1966; Arafa et al., 1981; Giambrone et al., 1985; Huff et al., 1986; Kubena et al., 1995; Klein et al., 2000), which was first demonstrated when this mycotoxin was discovered as…
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6,637
The Arriaga method is conceptually simple and easy to interpret and has been widely used to decompose life expectancy differences in the United States and elsewhere [2, 24–26, 30].
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6,638
Similar results have been demonstrated under metformin treatments in different breast cancer cell lines [7, 8].
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6,639
Zif268 was chosen here since it is a transcription factor well characterized for its role in synaptic plasticity and memory processing (Bozon et al. 2003) and has been shown to be crucial in instrumental learning (Maroteaux et al. 2014).
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6,640
Studies report that 10–25 % of healthy individuals are nonresponders to lutein supplementation using HFP [13, 16, 17] or RRS [35] mea-
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6,641
Example networks for some breeding units were drawn using an R package latentnet (Krivitsky and Handcock 2008).
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method
6,642
For nanotechnology and nano-foods, Siegrist et al. (2007) created a hypothetical model where Swiss consumer’s social trust (in nanotechnology producers) impacted perceptions of nanotechnology food information, which in turn fed into consumer benefit and risk perceptions, ultimately determining…
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6,643
Catecholamines, and particularly DA, are believed to increase the efficiency of cortical processing by augmenting the signal-tonoise ratio or gain within cortical networks [4,37–39].
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6,644
It has been generally accepted that planted wetlands outperform unplanted filters, and there is a positive correlation between plant uptake and nutrient removal from agricultural treatment wetlands (Comin et al., 1997; Huett et al., 2005; Gottschall et al., 2007).
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6,645
The valence electron occupation of the double dot was (2,1) or (1,2), as confirmed by magnetospectroscopy measurements30.
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6,646
However, the broad substrate specificity of the AtPLT5 and the unchanged phenotype of Atplt5-knock-out plants make it difficult to speculate on the physiological role of AtPLT5 (Klepek et al. 2005; Reinders et al. 2005).
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6,647
Reduction of the pentavalent to the trivalent forms can also be catalysed by GSTO1-1 or non-enzymatically (Cohen et al., 2006; Tapio and Grosche, 2006).
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6,648
The standard target for dystonia in children is the internal globus pallidus (GPi) [2], based on use of this target to reduce dyskinesias in patients with Parkinson’s disease.
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6,649
Both healthy and sick people increasingly use electronic media to obtain medical information and advice [1].
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6,650
There is evidence showing the feasibility of using screening tools at primary health care level in Zimbabwe [34, 41, 44, 60] but these tools are not integrated into HIV care programs.
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6,651
Mouse mAb G19 directed against the TLA from chicken inner ear hair cells, mAb D10 directed against the avian hair-cell antigen, and antisera to protocadherin-15-CD1 (PB303) were characterized and validated as reported previously (Richardson et al., 1990; Ahmed et al., 2003; Goodyear and Richardson, 2003).
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6,652
Both COSMOS and COMANCHE are based on the FRACTAL component model and use the JULIA10 implementation of the FRACTAL runtime environment [Bruneton et al., 2006b].
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6,653
Brain regions were identified using theWake Forest PickAtlas software (Wake Forest University, USA; www.fmri.wfubmc. edu) and the Talairach Atlas labels (Lancaster et al. 2000) as implemented in the xjView toolbox (http://www.alivelearn. net/xjview).
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6,654
Moreover, mRNA levels varied reciprocally over time with both villous height and crypt depth, which previously were found to be positively correlated with each other in the present population [18].
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6,655
A calibration study indicated acceptable correlations between the QFFQ and 24-h recalls for all sex and ethnic groups (23).
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6,656
According to Kunito et al. (2004), the biological half-life is rather long for trace-elements with high affinity to SH group in cysteine (Cd,Hg), leading to the age dependent increase in the concentration in toppredators.
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6,657
lucifugus, we observed declines that began in 2004, two years prior to the first recorded instance of the disease in the region [34].
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8) on the MMSE), diagnosed with amnestic MCI based on the Petersen criteria (Petersen et al. 1999); and 16 CN subjects (mean age 73(9) years; mean score 29.
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6,659
In contrast to human capital approach, these methods represent rather macroeconomic perspective and measure actual production losses [18, 19].
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6,660
Diagnostic yield has increased over time as such arrays have evolved to include better coverage [7–21].
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6,661
017 (Katoh and Standley 2013), and GBlocks (Castresana 2000) was used to remove poorly aligned, A cc ep te d A rti cl e This article is protected by copyright.
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6,662
Given than embodied synchrony is shown to correlate with mental processes and trust of interactants [144, 95], it is expected that interaction phase will affect the emotional response to robot’s behavior and this dependence should be taken into account when quantifying this response.
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6,663
Patients were assessed with the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) Affective Disorders Evaluation (Sachs et al., 2002, 2003), which included the mood disorders module of the Structured Clinical Interview for DSM (First et al., 1996) and Clinical Global…
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6,664
ALK3 and ALK6 are BMP receptors [18,19], ALK5 is a TGFβ receptor [18,20], and ALK4 is an Activin receptor [21].
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6,665
DRS scores as reported were adjusted for participant age and education (Age and Education Corrected Moan’s Scaled Score, or “AEMSS”; according to the DRS reference manual; www.psychassessments.com).
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6,666
The majority of oceanographic variables included in the model calculations are taken from the Regional Ocean Modeling System (ROMS) model coupled with the CoSiNE (Carbon, Silicate and Nitrogen Ecosystem) model (Chai et al., 2002, 2009; Dugdale et al., 2002a; Liu and Chai, 2009a, b).
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6,667
The estimation problem is regarded as maximum likelihood estimation for beta-binomial mixtures, and thus can be solved as a simpler case of well-established maximum likelihood estimation for Dirichlet-multinomial mixtures described in [20].
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6,668
Exomes from each NSCLC patient were examined using FannsDB [16], FATHMM [16], Mutation Assessor [17], Polyphen [18], PROVEAN [19], and SIFT [20].
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6,669
These properties have been noticed by others who used ̂κ in place of ̂ (Friedman 1989; Brown et al. 1999), and they can be exploited to reduce the computation time for regularized discriminant analysis in high-dimensional settings (Hastie and Tibshirani 2004). • R̂λ can be calculated by multiplying all off-diagonal elements of R̂ by λ. • The proposed regularization will reduce the bias inherent in eigenvalues of sample correlation matrices (Friedman 1989), provided that a reasonable choice of regularization parameter λ is used. Bias generally will not be completely removed. • R̂λ manages a bias–variance trade-off; R̂ has potentially high variance but relatively little bias (being asymptotically unbiased for large N , fixed p), and I has no variance, but is biased for R in general. Thus, loosely speaking, R̂λ can be thought of as a weighted average of a variance term and a bias term, and we aim to choose λ to optimize this bias–variance trade-off. Ledoit and Wolf (2004) previously made this point for ̂κ .
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The frequency and also the mutation pattern we found were in concordance with the data from the literature (Ohashi et al, 1995).
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6,671
inflammatory response in endothelial cells, resulting in elevated expression of adhesion molecules and increased endothelial permeability (4, 64), Figure 3.
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This is particularly significant in light of the 2010 guidelines from the British Society for Rheumatology (BSR) and British Health Professionals in Rheumatology (BHPR) [10], which propose that the threshold for treating RA patients with TNF-α inhibitors (adalimumab, etanercept or infliximab) following trials of two DMARDs, including MTX, should be lowered from 5.
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The presence of valvular heart disease was evaluated according to the current guidelines [11, 13, 14].
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For example, there are striking similarities in the ion channel complements employed in astrocytic endfeet and endothelial cells, enabling dual control of smooth muscle from either side of the blood-brain barrier (Longden et al. 2016; cf. Sudduth et al. 2017).
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, in normal T cells, the activation threshold to produce IFN-c is lower than that required for entry into the cell-cycle or to secrete IL-2 [31,32]).
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…identification and analysis of putative promoter sequence was conducted using the ProScan suite of programs (http://thr.cit.nih.gov/molbio/ proscan/) using the default settings [Prestridge, 2000] as per our previous gene characterization protocols [Philibert et al., 1999; Philibert et al., 2000].
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A previous study demonstrated age-related declines in song performance in Bengalese finches that were 6 yr of age (Cooper et al. 2012).
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Surgery, cryotherapy and brachytherapy are among the most frequently used local salvage treatment options with different degrees of success [2-11].
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, Behera and Yamagata, 2001; Reason, 2002), as well as links between the SST anomalies across the eastern Indian Ocean and regional rainfall (Nicholls, 1989; Frederiksen and Balgovind, 1994; England et al., 2006; Ummenhofer et al., 2008c).
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…of BDNF in the medial prefrontal cortex (mPFC) suppresses cocaine seeking (Berglind et al., 2007, 2009;Sadri-Vakili et al., 2010; Whitfield et al., 2011), whereas elevation of BDNF in the VTA (Lu et al., 2004a) and NAc shell (Graham et al., 2007; Graham et al., 2009) facilitates cocaine seeking.
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It has been described previously that pOPC isolated with this technique differentiate with time (4–6 days in vitro; DIV4-6) into oligodendrocytes and astrocytes [38], however OPC make up the large majority (80–90% of all DAPI+ cells) during the first two days of culture (Fig 1A and 1B).
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Comparable results were found in studies on teleosts (Carassius auratus, e.g. Salas et al. 1996a, b; Rodrı́guez et al. 2002a; Portavella et al. 2002; Broglio et al. 2005; Durán et al. 2008).
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Holistic thinkers tend to see the “whole picture” rather than the components constituting it, while analytic thinkers focus more on the components in lieu of the whole context (Monga and John, 2008; Nisbett et al., 2001).
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, 1998), finger tapping (Wassermann et al., 1996; Chen et al., 1997), peak force, and acceleration during finger pinch (Muellbacher et al.
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The inter-relationships between K1, K1O and anticoagulants in dogs and humans have been previously investigated [25, 26].
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We employed the same design as Dohmen et al. (2010) to measure the mothers’ risk preferences.5 At the daycare centers, we conducted experiments with the children to obtain behavioral measures of their willingness to compete and, as a control variable, their risk attitudes.
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17 CVL1/CVP2 In Arabidopsis thaliana, PtdIns(4,5)P2 is dephosphorylated by the 5TPases COTYLEDON VASCULAR PATTERN 2 (CVP2) and CVP2 LIKE 1 (CVL1) (Carland and Nelson, 2009; Carland and Nelson, 2004).
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However, discretionary policy can result in expectations traps and 1 multiple equilibria, see Albanesi et al. (2003), King and Wolman (2004) and Blake and Kirsanova (2012), and a simple New Keynesian model is not appropriate to investigate many consequences of policy delegation.
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3) revealed that the first two ON1 viruses detected in 2011–2012 (MAD8851/11 and MAD8921/12), clustered together with strains from Canada [Eshaghi et al., 2012], USA [Schobel et al.
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While the general decline in MVT deaths rates has been associated with multi-pronged prevention efforts as well as reduced driving among older adolescents (2,8), the sharp drop beginning in 2007 has also been associated with the economic recession in the United States (9).
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, the average number of nucleotide substitutions that accumulated along the branch from the founder strain as a function of time [13], is measured by the mean value of d, i.
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The central motif sequence GARGQAGVMGFO corresponding to amino acids 394–405 has the highest binding affinity for DDR2.(27) This binding site overlaps with the binding site of another soluble collagen-binding protein von Willebrand factor (vWF) in collagen type 3,(27) and is in close proximity to a binding site for decorin on collagen type 1.
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Each of the following databases, HUGO [5], ExPASy [2,7] (Swiss-Prot and TREMBL names), ENSEMBL [3], GenBank [4], FlyBase [6] and Gene Ontology [9], comes with a list of synonyms, which were downloaded and entered into a separate table for each dataset.
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Reference Noise Exposure Air Pollution Exposure Health Outcome Sample Adjustments Direction of Evidence Hypertension and Atherosclerosis Sørensen et al, 2011 [8] RTN SOUNDPLAN using Nordic prediction model from 5 years prior to enrolment to 2000–2002.
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However, the k-safeness of the hypercube does not guarantee the connectivity of the network unless we also bound the number of faulty nodes by 2(n − k) − 1 [17, 35].
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These results are in accordance to the expected half-life of albumin in humans (Noort et al., 2008).
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The magnitude of these differences is exaggerated by the high impact of annual burning on bird abundance and nesting success (Little et al. 2013) (Table 3).
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[7] provided us with the executable file of their signal selection implementation and we used it for the selection process.
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These results are in agreement with a study by WikstroÃàm et al. (2007) in which loss of AMH expression was also observed to occur at a later age in 14 KS patients.
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