id
stringlengths
1
5
tokens
sequence
ner_tags
sequence
5770
[ "Alveolar", "macrophages", "are", "located", "directly", "in", "the", "surrounding", "of", "these", "cells", ",", "so", "that", "we", "suppose", "an", "interaction", "between", "epithelial", "cells", "and", "macrophages", "regarding", "to", "the", "release", "of", "inflammatory", "mediators", "." ]
[ 7, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0, 7, 0, 0, 0, 0, 0, 9, 10, 0 ]
17912
[ "An", "increased", "growth", "rate", "of", "these", "Jurkat-tat", "cell", "lines", "as", "compared", "with", "control", "cell", "lines", "was", "observed", "." ]
[ 0, 0, 0, 0, 0, 0, 5, 6, 6, 0, 0, 0, 5, 6, 6, 0, 0, 0 ]
12024
[ "Viral", "reactivation", "from", "latency", "and", "spread", "from", "this", "lymphoid", "reservoir", "is", "presumably", "required", "for", "development", "of", "nonlymphoid", "tumors", "like", "KS", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
17369
[ "The", "interleukin", "2", "(", "IL-2", ")", "gene", "promoter", "is", "recognized", "by", "several", "cell-type-specific", "and", "ubiquitous", "transcriptional", "regulators", "that", "integrate", "information", "transmitted", "by", "various", "signaling", "systems", "leading", "to", "IL-2", "production", "and", "T-cell", "activation", "." ]
[ 0, 1, 2, 2, 2, 2, 2, 2, 0, 0, 0, 0, 9, 10, 10, 10, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 7, 0, 0 ]
16963
[ "There", "was", "evidence", "for", "an", "autosomal", "recessive", "form", "of", "inheritance", "in", "four", "families", ",", "while", "the", "other", "four", "families", "appeared", "to", "have", "an", "autosomal", "dominant", "mode", "of", "transmission", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
12605
[ "Binding", "to", "kappaB", "sequence", "was", "accompanied", "by", "an", "initial", "decrease", "and", "subsequent", "increase", "in", "the", "cytoplasmic", "IkappaBalpha", "levels", ",", "as", "detected", "by", "Western", "blotting", "using", "an", "anti-IkappaBalpha", "antibody", "." ]
[ 0, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0 ]
3109
[ "To", "this", "aim", ",", "allergen-specific", "CD4+", "T", "cell", "clones", "(", "TCC", ")", "were", "generated", "from", "the", "peripheral", "blood", "of", "three", "atopic", "patients", ",", "and", "their", "cytokine", "profiles", "were", "analyzed", "." ]
[ 0, 0, 0, 0, 5, 6, 6, 6, 6, 0, 5, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0 ]
6359
[ "Blood", "samples", "were", "obtained", "prior", "to", "the", "injection", "and", "at", "1", ",", "2", ",", "4", ",", "8", "and", "24", "hr", "after", "the", "injection", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
2276
[ "Nuclear", "run-on", "experiments", "showed", "that", "THP", "inhibited", "transcription", "of", "the", "IL-1", "beta", "gene", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0 ]
7661
[ "Type", "I", "interferons", "(", "IFN-alpha", "and", "IFN-beta", ")", "and", "type", "II", "interferon", "(", "IFN-gamma", ")", "inhibit", "induction", "of", "these", "genes", "by", "IL-4", "and", "IL-13", "." ]
[ 9, 10, 10, 0, 9, 0, 9, 0, 0, 9, 10, 10, 0, 9, 0, 0, 0, 0, 0, 0, 0, 9, 0, 9, 0 ]
4112
[ "Sequence-specific", "DNA", "binding", "of", "the", "B-cell-specific", "coactivator", "OCA-B", "." ]
[ 0, 0, 0, 0, 0, 9, 10, 9, 0 ]
11395
[ "NAC", "was", "also", "effective", "in", "diminishing", "germline", "C", "epsilon", "transcription", ",", "and", "its", "potency", "was", "higher", "in", "cultures", "costimulated", "with", "IL-4", "and", "anti-CD40", "mAb", "than", "in", "those", "stimulated", "with", "IL-4", "alone", "." ]
[ 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 9, 10, 0, 0, 0, 0, 0, 9, 0, 0 ]
10279
[ "We", "conclude", "that", "cytokines", ",", "which", "signal", "through", "the", "interferon", "family", "of", "receptors", ",", "have", "comparable", "functional", "effects", "on", "B-CLL", "cells", "." ]
[ 0, 0, 0, 9, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 5, 6, 0 ]
17379
[ "Premenopausal", "patients", "with", "neither", "risk", "factor", "had", "a", "very", "low", "failure", "rate", "(", "2.6", "%", "at", "5", "years", ")", ",", "regardless", "of", "age", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
2264
[ "In", "contrast", ",", "CD38", "expression", "was", "not", "inducible", "by", "ATRA", "in", "HL-60R", "cells", ",", "transfected", "with", "a", "functional", "RAR", "beta", ",", "RAR", "gamma", ",", "or", "RXR", "alpha", "receptor", "." ]
[ 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 5, 6, 0, 0, 0, 0, 0, 9, 10, 0, 9, 10, 0, 0, 9, 10, 10, 0 ]
8742
[ "We", "provide", "evidence", "that", "several", "NF-kappaB", "complexes", "are", "constitutively", "found", "in", "the", "nuclei", "of", "thymocytes", "either", "freshly", "isolated", "from", "the", "thymus", "or", "maintained", "in", "coculture", "with", "autologous", "or", "heterologous", "TEC", "." ]
[ 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 7, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 0 ]
12714
[ "The", "nuclear", "factor-kappa", "B", "(", "NF-kappaB", ")", "family", "of", "transcription", "factors", "regulates", "genes", "involved", "in", "inflammation", ",", "cell", "proliferation", ",", "and", "cell", "differentiation", "." ]
[ 0, 9, 10, 10, 10, 10, 10, 10, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
2410
[ "In", "normal", "adults", "there", "is", "a", "direct", "significant", "correlation", "between", "plasma", "cortisol", "and", "Type", "I", "and", "between", "plasma", "cortisol", "and", "Type", "II", "receptors", "in", "mononuclear", "leukocytes", ",", "while", "in", "Cushing", "'s", "syndrome", "the", "correlation", "is", "inverse", "between", "plasma", "cortisol", "at", "8", "a.m.", "and", "Type", "II", "receptors", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 9, 10, 10, 0, 7, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0 ]
9772
[ "Polyclonal", "and", "clonal", "CTL", "that", "were", "generated", "by", "stimulating", "peripheral", "blood", "mononuclear", "cells", "with", "an", "HLA", "B8+", "homozygous", "LCL", "lysed", "T", "cell", "blasts", "pulsed", "with", "the", "peptide", ",", "RAKFKQLLQ", ";", "lysis", "of", "certain", "HLA", "B8+", "LCL", "targets", "was", "associated", "with", "the", "abundance", "of", "BZLF1", "transcripts", "." ]
[ 5, 6, 6, 6, 0, 0, 0, 0, 0, 7, 8, 8, 8, 0, 0, 5, 6, 6, 6, 6, 6, 6, 6, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0 ]
14292
[ "In", "the", "present", "study", ",", "analysis", "of", "the", "interleukin-2", "(", "IL-2", ")", "gene", "activation", "shows", "that", "naive", "human", "helper", "T", "cells", "(", "cord", "blood", "CD4+", "T", "cells", ",", "adult", "CD4+CD45RO-", "T", "cells", ")", "regulate", "IL-2", "transcription", "by", "a", "mechanism", "involving", "both", "a", "silencer", "and", "an", "activator", "acting", "on", "the", "purine-rich", "IL-2", "promoter", "elements", "(", "NF-AT", "binding", "sites", ")", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 2, 0, 0, 0, 7, 8, 8, 8, 8, 0, 7, 8, 8, 8, 8, 0, 7, 8, 8, 8, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 0, 0, 1, 2, 2, 2, 0, 1, 2, 2, 0, 0 ]
7959
[ "Furthermore", ",", "epithelial", "levels", "of", "activated", "Stat1", "correlated", "with", "levels", "of", "expression", "for", "epithelial", "ICAM-1", ",", "IRF-1", ",", "and", "Stat1", ",", "and", "in", "turn", ",", "ICAM-1", "levels", "correlated", "with", "T-cell", "accumulation", "in", "tissue", "." ]
[ 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 9, 10, 0, 9, 0, 0, 9, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0 ]
14842
[ "R7-57", "reporter", "cells", ",", "on", "the", "other", "hand", ",", "signaled", "induced", "activity", "of", "the", "lytic", "origin", "of", "EBV", "replication", "(", "ori", "Lyt", ")", "." ]
[ 5, 6, 6, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 2, 0, 1, 2, 0, 0 ]
10959
[ "Altogether", ",", "our", "data", "demonstrate", "that", ":", "(", "a", ")", "the", "ability", "of", "B", "cells", "to", "release", "TNF-alpha", "after", "triggering", "of", "HLA-DR", "antigens", "depends", "on", "their", "stage", "of", "differentiation", ";", "(", "b", ")", "levels", "of", "released", "TNF-alpha", "seem", "to", "correlate", "with", "the", "stage", "of", "B-cell", "maturation", "but", "do", "not", "correlate", "with", "the", "amounts", "of", "cell", "surface", "HLA-DR", "antigens", ";", "(", "c", ")", "secreted", "TNF-alpha", "regulates", "the", "levels", "of", "expression", "of", "NF-kappa", "B", "and", "AP-1", "by", "an", "autocrine", "loop", ";", "and", "(", "d", ")", "intracellular", "signals", "mediating", "TNF-alpha", "release", "by", "B", "cells", "are", "distinct", "from", "those", "regulating", "homotypic", "aggregation", "and", "proliferation", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0, 0, 9, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 10, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 9, 10, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
12105
[ "Here", "we", "demonstrate", "that", "the", "putative", "GAS", "element", "in", "the", "CAEV", "LTR", "binds", "specifically", "to", "a", "cellular", "factor", "induced", "by", "IFN-gamma", "in", "promonocytic", "cells", "." ]
[ 0, 0, 0, 0, 0, 0, 1, 2, 0, 0, 1, 2, 0, 0, 0, 0, 9, 10, 0, 0, 9, 0, 7, 8, 0 ]
2241
[ "To", "understand", "GATA3", "gene", "regulation", ",", "we", "cloned", "the", "human", "gene", "and", "the", "5", "'", "end", "of", "the", "mouse", "GATA3", "gene", "." ]
[ 0, 0, 1, 2, 0, 0, 0, 0, 0, 1, 2, 0, 0, 1, 2, 2, 0, 0, 1, 2, 2, 0 ]
14169
[ "Recently", ",", "many", "investigators", "have", "been", "interested", "in", "the", "study", "on", "eosinophil", "biology", "since", "genes", "association", "with", "eosinophils", "such", "as", "interleukin-5", "or", "eosinophil", "granule", "proteins", "(", "EPO", ",", "ECP", ",", "EDN", ",", "MBP", ",", "and", "CLC", ")", ",", "were", "isolated", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 0, 0, 0, 0, 0, 7, 0, 0, 9, 0, 9, 10, 10, 0, 9, 0, 9, 0, 9, 0, 9, 0, 0, 9, 0, 0, 0, 0, 0 ]
5242
[ "Thus", ",", "the", "induction", "of", "ICER", "in", "T", "cells", "may", "play", "an", "important", "role", "in", "the", "cAMP-induced", "quiescence", "and", "the", "persistent", "latency", "of", "HTLV-I", "." ]
[ 0, 0, 0, 0, 0, 9, 0, 7, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
11549
[ "We", "generated", "a", "point", "mutant", "of", "ZEBRA", ",", "Z", "(", "S186A", ")", ",", "that", "was", "not", "impaired", "in", "its", "ability", "to", "activate", "transcription", ";", "however", ",", "this", "mutation", "abolished", "its", "ability", "to", "initiate", "the", "viral", "lytic", "cascade", "." ]
[ 0, 0, 0, 0, 0, 0, 9, 0, 9, 10, 10, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
11515
[ "As2O3", "was", "administered", "intravenously", "at", "the", "dose", "of", "10", "mg/d", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
3126
[ "While", "the", "sera", "of", "EBV-negative", "individuals", "(", "0/3", ")", "or", "healthy", "carriers", "(", "0/33", ")", "did", "not", "contain", "detectable", "levels", "of", "antibodies", ",", "patients", "with", "mononucleosis", "(", "5/18", ")", ",", "chronic", "EBV", "infection", "(", "2/7", ")", ",", "EBV", "reactivation", "(", "7/20", ")", "and", "human", "immunodeficiency", "virus", "infection", "(", "5/24", ")", "showed", "elevated", "antibody", "titres", "against", "the", "enzyme", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
11223
[ "Human", "T-cell", "leukemia", "virus", "type", "I", "(", "HTLV-I", ")", "is", "an", "etiological", "agent", "of", "adult", "T-cell", "leukemia", "(", "ATL", ")", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
4476
[ "Stimulation", "by", "RA", "resulted", "in", "increased", "RAR", "beta", "/RXR", "DNA", "binding", ",", "activated", "RARE", "-dependent", "transcription", ",", "and", "increased", "expression", "of", "RAR-beta", "." ]
[ 0, 0, 0, 0, 0, 0, 9, 10, 9, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 9, 0 ]
15108
[ "2", "." ]
[ 0, 0 ]
9751
[ "Regulation", "of", "NF-kappa", "B", "activity", "by", "I", "kappa", "B", "alpha", "and", "I", "kappa", "B", "beta", "stability", "." ]
[ 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
4151
[ "Induction", "of", "activator", "protein", "(", "AP", ")", "-1", "and", "nuclear", "factor-kappaB", "by", "CD28", "stimulation", "involves", "both", "phosphatidylinositol", "3-kinase", "and", "acidic", "sphingomyelinase", "signals", "." ]
[ 0, 0, 9, 10, 10, 10, 10, 10, 0, 9, 10, 0, 9, 0, 0, 0, 9, 10, 0, 9, 10, 0, 0 ]
9764
[ "We", "found", "that", "removal", "of", "the", "TNF-alpha", "containing", "medium", "causes", "a", "rapid", "decrease", "in", "nuclear", "NF-kappa", "B", "." ]
[ 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0 ]
12969
[ "Furthermore", ",", "S9a", "and", "AZT", "in", "combination", ",", "at", "noncytoxic", "concentrations", "strongly", "inhibited", "HIV-1", "replication", "that", "was", "more", "than", "additive", "and", "substantially", "prolonged", "the", "appearance", "of", "virus", "both", "in", "acutely", "infected", "CD4+", "lymphocytes", "(", "SupT", ")", "in", "culture", "and", "in", "peripheral", "blood", "mononuclear", "cells", "(", "PBMCs", ")", "infected", "with", "a", "primary", "HIV-1", "isolate", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 8, 8, 0, 5, 0, 0, 0, 0, 0, 7, 8, 8, 8, 0, 7, 0, 0, 0, 0, 0, 0, 0, 0 ]
3173
[ "In", "patients", "with", "breast", "cancer", ",", "NK", "cell", "activity", "was", "significantly", "higher", "compared", "with", "patients", "with", "benign", "tumors", "(", "P", "=", "0.006", ")", "or", "healthy", "control", "subjects", "(", "P", "=", "0.002", ")", "." ]
[ 0, 0, 0, 0, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
17592
[ "NFAT-1", "activity", "had", "previously", "been", "thought", "to", "be", "confined", "to", "activated", "T-lymphocytes", "upon", "release", "of", "intracellular", "calcium", "." ]
[ 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0, 0, 0, 7, 8, 0 ]
10299
[ "We", "demonstrate", "that", "SLAP-130", "is", "hematopoietic", "cell-specific", "and", "associates", "with", "the", "SH2", "domain", "of", "SLP-76", "." ]
[ 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 9, 0 ]
1106
[ "Enhancement", "of", "IFNA", "synthesis", "observed", "upon", "HIV-1", "infection", "resulted", "in", "significant", "inhibition", "of", "HIV-1", "replication", "for", "a", "period", "of", "at", "least", "30", "days", "." ]
[ 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
4110
[ "However", ",", "the", "reduced", "expression", "of", "these", "proteins", "was", "not", "the", "result", "of", "a", "global", "TCR/CD3", "-signaling", "defect", "because", "CD3", "cross-linking", "induced", "an", "equivalent", "increase", "in", "intracellular-free", "calcium", "ions", ",", "as", "well", "as", "NFATp", "dephosphorylation", ",", "translocation", "to", "the", "nucleus", ",", "and", "DNA", "binding", "in", "both", "normal", "and", "anergic", "T", "cells", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 0, 5, 6, 6, 0 ]
2039
[ "The", "glutathione-depleting", "agent", "diethyl", "maleate", "(", "DEM", ")", "prevented", "the", "development", "of", "differentiated", "features", "in", "response", "to", "phorbol", "esters", ",", "including", "adherence", "of", "the", "cells", "to", "plastic", "surfaces", "and", "repression", "of", "the", "myeloperoxidase", "and", "CD34", "genes", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 0 ]
15058
[ "These", "results", "suggest", "that", "the", "decreased", "IL-2", "production", "and", "proliferative", "response", "displayed", "by", "PHA-activated", "PBL", "from", "elderly", "adults", "may", "be", "related", "to", "age-related", "changes", "in", "c-jun", "mRNA", "expression", "and", "in", "the", "ratio", "of", "c-fos", "to", "c-jun", "mRNA", "." ]
[ 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 5, 6, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0 ]
15669
[ "The", "candidate", "oncoprotein", "Bcl-3", "is", "an", "antagonist", "of", "p50/NF-kappa", "B", "-mediated", "inhibition", "." ]
[ 0, 9, 10, 10, 0, 0, 0, 0, 9, 10, 0, 0, 0 ]
10117
[ "Surprisingly", ",", "expression", "of", "neither", "BHRF1", "nor", "Bcl-2", "in", "a", "B-cell", "line", ",", "BJAB", ",", "protected", "the", "cells", "from", "anti-Fas-mediated", "apoptosis", "even", "though", "they", "increased", "the", "survival", "of", "serum-starved", "cells", "." ]
[ 0, 0, 0, 0, 0, 9, 0, 9, 0, 0, 5, 6, 0, 5, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0 ]
12062
[ "TIMP-1", "suppression", "of", "PCD", "is", "not", "due", "to", "metalloproteinase", "inhibition", ",", "as", "reduction", "and", "alkylation", "of", "the", "TIMP-1", "did", "not", "abolish", "this", "activity", "." ]
[ 9, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0 ]
11776
[ "These", "experiments", "demonstrate", "that", "HSV-1", "is", "a", "competent", "vector", "for", "expression", "of", "these", "VZV", "proteins", "and", "support", "the", "feasibility", "of", "engineering", "a", "combined", "vaccine", "for", "these", "closely", "related", "alpha-herpesviruses", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
18273
[ "These", "data", "indicate", "that", "the", "expression", "of", "CIITA", "explains", "the", "expression", "or", "lack", "of", "expression", "of", "MHC", "class", "II", "in", "human", "and", "mouse", "T", "cells", "respectively", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0, 7, 0, 7, 8, 8, 0, 0 ]
14371
[ "We", "show", "that", "the", "ability", "to", "detect", "NF-ATp", "in", "a", "gel", "shift", "assay", ",", "which", "is", "essential", "for", "purification", "and", "biochemical", "studies", "of", "this", "protein", ",", "is", "strikingly", "dependent", "on", "the", "precise", "sequence", "of", "the", "NF-AT", "oligonucleotide", "used", "as", "the", "labeled", "probe", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0 ]
6575
[ "As", "compared", "with", "other", "open-reading", "frames", "embedded", "into", "HIV/SIV", "genome", ",", "this", "degree", "of", "stability", "is", "unprecedented", "." ]
[ 0, 0, 0, 0, 1, 2, 0, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0 ]
12009
[ "Sequence", "analyses", "of", "cDNA", "clones", "indicated", "that", "these", "transcripts", "encode", "proteins", "differing", "only", "at", "their", "amino", "termini", ",", "and", "likely", "represent", "alternatively", "spliced", "isoforms", "." ]
[ 0, 0, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0 ]
9118
[ "Transcripts", "for", "osteoprotegerin", "ligand", "(", "OPGL", ")", ",", "an", "osteoclast", "differentiation", "factor", "(", "also", "known", "as", "RANKL", "and", "TRANCE", ")", "are", "expressed", ",", "likely", "by", "adherent", "cells", "." ]
[ 0, 0, 9, 10, 0, 9, 0, 0, 0, 9, 10, 10, 0, 0, 0, 0, 9, 0, 9, 0, 0, 0, 0, 0, 0, 7, 8, 0 ]
14544
[ "Purified", "recombinant", "Jun", "and", "Fos", "proteins", "failed", "to", "bind", "directly", "to", "the", "NFAT", "motif", "." ]
[ 0, 0, 9, 10, 10, 10, 0, 0, 0, 0, 0, 0, 1, 2, 0 ]
16974
[ "Higher", "NK", "activity", "could", "be", "predicted", "by", "the", "perception", "of", "high", "quality", "emotional", "support", "from", "a", "spouse", "or", "intimate", "other", ",", "perceived", "social", "support", "from", "the", "patient", "'s", "physician", ",", "estrogen", "receptor", "-negative", "tumor", "status", ",", "having", "an", "excisional", "biopsy", "as", "surgical", "treatment", ",", "and", "actively", "seeking", "social", "support", "as", "a", "major", "coping", "strategy", "(", "R2", "=", "0.33", ",", "F", "(", "5", ",", "55", ")", "=", "5.5", ",", "p", "less", "than", "0.0004", ")", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
16271
[ "Consistent", "with", "this", "short", "t1/2", ",", "accumulation", "of", "1", ",", "25", "(", "OH", ")", "2D3", "receptor", "RNA", "increased", "in", "cells", "as", "their", "protein", "synthesis", "was", "inhibited", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 4, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
12693
[ "Proper", "expression", "of", "the", "genes", "of", "the", "human", "beta-globin", "gene", "locus", "requires", "the", "associated", "locus", "control", "region", "(", "LCR", ")", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 0, 0, 0, 1, 2, 2, 0, 1, 0, 0 ]
4858
[ "Soluble", "tumor", "necrosis", "factor", "receptors", "inhibit", "phorbol", "myristate", "acetate", "and", "cytokine-induced", "HIV-1", "expression", "chronically", "infected", "U1", "cells", "." ]
[ 9, 10, 10, 10, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 8, 0 ]
1246
[ "Furthermore", ",", "we", "found", "that", "the", "induction", "by", "hydrogen", "peroxide", "of", "NF-kappa", "B", "translocation", "to", "the", "nucleus", ",", "which", "is", "assumed", "to", "be", "triggered", "by", "reactive", "oxygen", "intermediates", ",", "also", "coincided", "with", "incorporation", "of", "phosphate", "into", "the", "same", "subunits", "that", "were", "modified", "after", "stimulation", "by", "TNF-alpha", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0 ]
12991
[ "[", "Molecular", "mechanism", "of", "cytokine", "gene", "expression", "in", "Th1", "and", "Th2", "]" ]
[ 0, 0, 0, 0, 1, 2, 0, 0, 5, 0, 5, 0 ]
3194
[ "However", ",", "IL-4", "-induced", "effects", "were", "clearly", "improved", "following", "JAK3", "expression", "." ]
[ 0, 0, 9, 0, 0, 0, 0, 0, 0, 9, 0, 0 ]
16914
[ "Two", "glucocorticoid", "binding", "sites", "on", "the", "human", "glucocorticoid", "receptor", "." ]
[ 0, 9, 10, 10, 0, 0, 9, 10, 10, 0 ]
3070
[ "We", "initiated", "this", "study", "to", "determine", "1", ")", "the", "prevalence", "of", "one", "or", "more", "breast", "tissue", "abnormalities", "in", "a", "group", "of", "women", "at", "high", "risk", "for", "breast", "cancer", ",", "and", "2", ")", "if", "the", "prevalence", "of", "biomarker", "abnormalities", "is", "greater", "in", "high", "risk", "than", "in", "low", "risk", "women", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
10996
[ "An", "increasing", "body", "of", "evidence", "suggests", "that", "amyloid-beta", "(", "A", "beta", ")", "peptides", "and", "microglia", "are", "crucially", "involved", "in", "the", "pathogenesis", "of", "Alzheimer", "'s", "disease", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
14126
[ "The", "retinoblastoma", "gene", "product", "(", "Rb", ")", "is", "a", "nuclear", "phosphoprotein", "that", "regulates", "cell", "cycle", "progression", "." ]
[ 0, 9, 10, 10, 0, 9, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0 ]
18540
[ "The", "stimulatory", "effects", "of", "gp160", "are", "mediated", "through", "the", "CD4", "molecule", ",", "since", "treatment", "of", "gp160", "with", "soluble", "CD4-IgG", "abrogates", "its", "activity", ",", "and", "CD4", "negative", "T", "cell", "lines", "fail", "to", "be", "stimulated", "with", "gp160", "." ]
[ 0, 0, 0, 0, 9, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 9, 0, 0, 9, 0, 0, 0, 0, 0, 5, 6, 6, 6, 6, 0, 0, 0, 0, 0, 9, 0 ]
12681
[ "In-vitro", "transcription/translation", "of", "this", "cDNA", "expressed", "a", "protein", "of", "approximately", "20", "kDa", "." ]
[ 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]
8203
[ "Soluble", "interleukin-2", "receptor-alpha", "(", "IL-2Ralpha", ")", "has", "been", "reported", "to", "be", "increased", "in", "the", "sera", "of", "patients", "with", "advanced", "tuberculosis", ",", "and", "levels", "decline", "after", "therapy", "in", "accordance", "with", "improvement", "of", "radiologic", "findings", "." ]
[ 0, 9, 10, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
3786
[ "The", "role", "of", "egr-1", "in", "regulation", "of", "the", "immune", "response", "will", "be", "discussed", "in", "the", "context", "of", "these", "recent", "studies", "." ]
[ 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
3514
[ "To", "analyze", "the", "regulatory", "mechanisms", "controlling", "p27Kip1", "gene", "expression", ",", "we", "characterized", "the", "5'-flanking", "region", "from", "nt", "-1609", "to", "+178", "." ]
[ 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 2, 0, 1, 2, 2, 2, 0 ]
16126
[ "Prolonged", "corticosteroid", "treatment", "resulted", "in", "down-regulation", "of", "GcR", ",", "while", "the", "mean", "level", "of", "GcR", "in", "Cushing", "'s", "disease", "was", "normal", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0 ]
14301
[ "Treatment", "of", "HL-60", "eosinophilic", "sublines", "with", "either", "interleukin-5", "or", "butyric", "acid", "increased", "the", "expression", "of", "GATA-1", "mRNA", "concomitant", "with", "the", "expression", "of", "eosinophil-specific", "genes", ",", "whereas", "levels", "of", "GATA-2", "mRNA", "remained", "relatively", "constant", "." ]
[ 0, 0, 5, 6, 6, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 0, 0, 0, 0, 1, 2, 0, 0, 0, 0, 3, 4, 0, 0, 0, 0 ]
11745
[ "An", "E2F-4/p130", "complex", "was", "detected", "in", "representative", "samples", "of", "all", "FAB", "types", "analysed", "." ]
[ 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0 ]
2129
[ "Central", "nervous", "system-derived", "cells", "express", "a", "kappa", "B-binding", "activity", "that", "enhances", "human", "immunodeficiency", "virus", "type", "1", "transcription", "in", "vitro", "and", "facilitates", "TAR", "-independent", "transactivation", "by", "Tat", "." ]
[ 7, 8, 8, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 9, 0 ]
459
[ "Expression", "of", "the", "protooncogene", "c-fos", "is", "controlled", "by", "three", "main", "regulatory", "pathways", "involving", "kinase", "C", ",", "cAMP", ",", "and", "calcium", "." ]
[ 0, 0, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0 ]
2407
[ "A", "similarity", "has", "recently", "been", "found", "between", "the", "regulation", "of", "corticosteroid", "receptors", "in", "brain", "and", "in", "lymphoid", "tissue", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0 ]
6488
[ "Furthermore", ",", "IL-2", "and", "IL-12", "synergistically", "induced", "IRF-1", ",", "whereas", "IFN-alpha", "and", "IL-12", "did", "not", "." ]
[ 0, 0, 9, 0, 9, 0, 0, 9, 0, 0, 9, 0, 9, 0, 0, 0 ]
1169
[ "Accompanying", "the", "rapid", "turnover", "of", "the", "I", "kappa", "B", "alpha", "protein", "is", "simultaneous", "translocation", "of", "NF-kappa", "B-related", "transcription", "factors", "to", "nuclei", "of", "adhered", "monocytes", "." ]
[ 0, 0, 0, 0, 0, 0, 9, 10, 10, 10, 10, 0, 0, 0, 0, 9, 10, 10, 10, 0, 0, 0, 0, 0, 0 ]
5309
[ "We", "found", "that", "treatment", "with", "dexamethasone", "induced", "eosinophil", "apoptosis", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 7, 0, 0 ]
9020
[ "The", "reduction", "in", "gene", "expression", "resulted", "from", "the", "ability", "of", "IL-10", "to", "suppress", "IFN", "-induced", "assembly", "of", "signal", "transducer", "and", "activator", "of", "transcription", "(", "STAT", ")", "factors", "to", "specific", "promoter", "motifs", "on", "IFNalpha-", "and", "IFNgamma-inducible", "genes", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 9, 0, 0, 0, 9, 10, 10, 10, 10, 10, 10, 10, 10, 10, 0, 1, 2, 2, 0, 1, 2, 2, 2, 0 ]
17387
[ "The", "proteins", "identified", "have", "molecular", "weights", "of", "about", "32", ",", "36", "to", "42", ",", "50", "and", "110", "kD", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
12167
[ "Extract", "of", "Tripterygium", "wilfordii", "Hook.", "f", "(", "TWHf", ")", "has", "immunosuppressive", "activity", "and", "has", "been", "used", "as", "anti-inflammatory", "agent", "in", "traditional", "Chinese", "medicine", "for", "centuries", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
14740
[ "Adenovirus", "can", "establish", "persistent", "infections", "which", "may", "reactivate", "and", "cause", "disease", "in", "immunocompromised", "hosts", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
7433
[ "Its", "differential", "expression", "in", "different", "tissues", "and", "cells", "is", "regulated", "not", "only", "at", "the", "transcriptional", "level", "but", "also", "at", "the", "translational", "level", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
14765
[ "Cytogenetic", "studies", "of", "the", "primate", "Y", "chromosomes", "have", "suggested", "that", "extensive", "rearrangements", "have", "occurred", "during", "evolution", "of", "the", "great", "apes", "." ]
[ 0, 0, 0, 0, 1, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
6768
[ "Moreover", ",", "supernatants", "from", "DEP-PAH-activated", "cells", ",", "compared", "with", "those", "of", "controls", ",", "exhibited", "a", "significantly", "enhanced", "chemotactic", "activity", "for", "neutrophils", "and", "eosinophils", ",", "which", "was", "significantly", "inhibited", "by", "pretreatment", "with", "anti-IL-8", "and", "anti-RANTES", "neutralizing", "antibodies", ",", "respectively", "." ]
[ 0, 0, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 0, 7, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 9, 0, 0, 0, 0, 0 ]
18370
[ "HU", "induced", "a", "dose-dependent", "stimulation", "of", "c-jun", "synthesis", "." ]
[ 0, 0, 0, 0, 0, 0, 1, 0, 0 ]
4386
[ "There", "is", "increasing", "evidence", "that", "lipoproteins", "of", "Treponema", "pallidum", "and", "Borrelia", "burgdorferi", "are", "key", "inflammatory", "mediators", "during", "syphilis", "and", "Lyme", "disease", "." ]
[ 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
3627
[ "Stimulation", "of", "human", "peripheral", "blood", "mononuclear", "cells", "by", "zinc", "and", "related", "cations", "." ]
[ 0, 0, 7, 8, 8, 8, 8, 0, 0, 0, 0, 0, 0 ]
9598
[ "CONCLUSIONS", ":", "MZF-1", "and", "MZF-2", "mRNAs", "seem", "to", "be", "produced", "by", "the", "alternative", "use", "of", "two", "different", "transcription", "initiation", "sites", "." ]
[ 0, 0, 3, 4, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0 ]
18172
[ "According", "to", "our", "results", ",", "however", ",", "the", "kinases", "responsible", "for", "the", "two", "processes", "are", "distinct", "entities", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
16793
[ "Upon", "activation", ",", "T", "lymphocytes", "accumulate", "high", "levels", "of", "the", "neuropeptide", "enkephalin", "which", "correlate", "with", "high", "levels", "of", "proenkephalin", "mRNA", "in", "the", "cells", "." ]
[ 0, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 0, 0, 0 ]
8901
[ "This", "GAG", "also", "possesses", "immunomodulatory", "activity", "in", "vivo", "and", "can", "antagonize", "the", "capacity", "of", "IFN-gamma", "to", "induce", "class", "II", "MHC", "antigen", "expression", ",", "and", "to", "up-regulate", "intercellular", "adhesion", "molecule-1", ",", "by", "cultured", "endothelial", "cells", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 9, 10, 10, 10, 0, 0, 0, 0, 0, 9, 10, 10, 0, 0, 5, 6, 6, 0 ]
16916
[ "Cortisol", "and", "various", "synthetic", "glucocorticoids", "bind", "to", "the", "GR", "with", "one-site", "kinetics", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0 ]
1535
[ "Tumor", "necrosis", "factor", "alpha", "(", "TNF", "alpha", ")", "is", "particularly", "important", "in", "this", "process", "because", "of", "its", "ability", "to", "regulate", "other", "inflammatory", "mediators", "in", "an", "autocrine", "and", "paracrine", "fashion", "." ]
[ 9, 10, 10, 10, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
16610
[ "These", "studies", "have", "been", "extended", "to", "show", "that", "(", "i", ")", "a", "mutant", "EBV", "strain", "lacking", "the", "gene", "encoding", "EBNA", "2", "fails", "to", "switch", "from", "Wp", "to", "Cp", "usage", "in", "primary", "B", "lymphocytes", ",", "although", "the", "virus", "contains", "a", "functional", "Cp", ";", "(", "ii", ")", "a", "region", "from", "-429", "to", "-245", "base", "pairs", "upstream", "of", "Cp", "is", "essential", "for", "Cp", "activity", "in", "B", "lymphocytes", ",", "but", "only", "in", "the", "context", "of", "upstream", "and", "downstream", "sequences", ";", "(", "iii", ")", "this", "region", "contains", "an", "EBNA", "2-dependent", "enhancer", ";", "and", "(", "iv", ")", "DNase", "I", "protection", "employing", "nuclear", "extracts", "from", "B", "and", "T", "lymphocytes", "revealed", "a", "B-cell-specific", "footprint", "in", "the", "region", "of", "the", "EBNA", "2-dependent", "enhancer", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 1, 0, 0, 7, 8, 8, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 2, 0, 0, 1, 0, 0, 0, 1, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 7, 8, 8, 8, 0, 0, 1, 2, 0, 0, 0, 0, 0, 1, 2, 2, 0 ]
7232
[ "Analyses", "of", "mouse", "strains", "with", "congenital", "defects", "in", "different", "aspects", "of", "secondary", "lymphoid", "tissue", "development", "are", "beginning", "to", "clarify", "the", "role", "of", "these", "tissues", "in", "immune", "responses", "and", "host", "defense", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
14351
[ "ras", "protein", "activity", "is", "essential", "for", "T-cell", "antigen", "receptor", "signal", "transduction", "." ]
[ 9, 10, 0, 0, 0, 0, 9, 10, 10, 0, 0, 0 ]
5218
[ "Binding", "and", "cooperative", "interactions", "between", "two", "B", "cell-specific", "transcriptional", "coactivators", "." ]
[ 0, 0, 0, 0, 0, 0, 9, 10, 10, 10, 0 ]
1421
[ "These", "results", "suggest", "that", "the", "activation", "of", "NF-kappa", "B", "plays", "an", "important", "role", "in", "the", "apoptotic", "process", "of", "human", "hematopoietic", "cells", "." ]
[ 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 8, 0 ]