Datasets:
siddharthtumre
/
Revised-JNLPBA

Dataset card Data Studio Files Community
1
id
stringlengths
1
5
tokens
sequence
ner_tags
sequence
6501
[ "This", "remodeling", "of", "promoter", "chromatin", "structure", "resulted", "in", "3-fold", "increases", "in", "beta-globin", "gene", "transcription", "and", "induction", ",", "and", "inhibited", "long-term", "beta-globin", "gene", "silencing", "." ]
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6502
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6503
[ "Regulation", "of", "low", "shear", "flow-induced", "HAEC", "VCAM-1", "expression", "and", "monocyte", "adhesion", "." ]
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6504
[ "We", "recently", "reported", "that", "prolonged", "exposure", "of", "human", "aortic", "endothelial", "cells", "(", "HAEC", ")", "to", "low", "shear", "stress", "flow", "patterns", "is", "associated", "with", "a", "sustained", "increase", "in", "the", "activated", "form", "of", "the", "transcriptional", "regulator", "nuclear", "factor-kappaB", "(", "NF-kappaB", ")", "." ]
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6505
[ "Here", "we", "investigate", "the", "hypothesis", "that", "low", "shear-induced", "activation", "of", "NF-kappaB", "is", "responsible", "for", "enhanced", "expression", "of", "vascular", "cell", "adhesion", "molecule", "(", "VCAM-1", ")", "resulting", "in", "augmented", "endothelial", "cell-monocyte", "(", "EC-Mn", ")", "adhesion", "and", "that", "this", "activation", "is", "dependent", "on", "intracellular", "oxidant", "activity", "." ]
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6506
[ "Before", "exposure", "to", "low", "shear", "(", "2", "dyn/cm2", ")", "for", "6", "h", ",", "HAEC", "were", "preincubated", "with", "or", "without", "the", "antioxidants", "pyrrolidine", "dithiocarbamate", "(", "PDTC", ")", "or", "N-acetyl-L-cysteine", "(", "NAC", ")", "." ]
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6507
[ "PDTC", "strongly", "inhibited", "low", "shear-induced", "activation", "of", "NF-kappaB", ",", "expression", "of", "VCAM-1", ",", "and", "EC-Mn", "adhesion", "." ]
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6508
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6509
[ "However", ",", "cytokine-induced", "NF-kappaB", "activation", "and", "VCAM-1", "expression", "are", "blocked", "by", "both", "PDTC", "and", "NAC", "." ]
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6510
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6511
[ "Nuclear", "factor-90", "of", "activated", "T-cells", ":", "A", "double-stranded", "RNA", "-binding", "protein", "and", "substrate", "for", "the", "double-stranded", "RNA-dependent", "protein", "kinase", ",", "PKR", "." ]
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6512
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6513
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6514
[ "Multiple", "proteins", "exhibiting", "ARRE-2", "binding", "activity", "have", "been", "isolated", ",", "including", "a", "heterodimer", "from", "stimulated", "T-cell", "nuclear", "extracts", "consisting", "of", "Mr", "=", "90", "000", "(", "NF90", ")", "and", "Mr", "=", "45", "000", "(", "NF45", ")", "subunits", "." ]
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6515
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6516
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6517
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6518
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6519
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6520
[ "NF-kappaB", "activation", "is", "required", "for", "C5a-induced", "interleukin-8", "gene", "expression", "in", "mononuclear", "cells", "." ]
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6521
[ "C5a", ",", "a", "potent", "peptide", "chemoattractant", ",", "stimulates", "interleukin-8", "(", "IL-8", ")", "secretion", "from", "peripheral", "blood", "mononuclear", "cells", "(", "PBMC", ")", "." ]
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6522
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6523
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6524
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6525
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6526
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6527
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6528
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6529
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6530
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6531
[ "The", "molecular", "basis", "of", "GC", "insensitivity", "is", "unknown", "." ]
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6532
[ "Alternative", "splicing", "of", "the", "GC", "receptor", "(", "GCR", ")", "pre-mRNA", "generates", "a", "second", "GCR", ",", "termed", "GCRbeta", ",", "which", "does", "not", "bind", "GC", "but", "antagonizes", "the", "transactivating", "activity", "of", "the", "classic", "GCR", "." ]
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6533
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6534
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6535
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6536
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6537
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6538
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6539
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6540
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6541
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6542
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6543
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6549
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6550
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6554
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[ "Novel", "therapies", "for", "inflammatory", "bowel", "disease", "." ]
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6559
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6560
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6564
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6565
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6566
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6567
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6568
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6569
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6570
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6571
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6572
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6573
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6574
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6575
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6576
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6577
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6578
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6579
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6580
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6581
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6582
[ "We", "show", "here", "that", "in", "addition", "to", "the", "strong", "N-terminal", "trans-activation", "domain", ",", "TAD-A", ",", "which", "is", "common", "to", "all", "three", "NF-ATc", "isoforms", ",", "NF-ATc/C", "contains", "a", "second", "trans-activation", "domain", ",", "TAD-B", ",", "in", "its", "C-terminal", "peptide", "." ]
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6583
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6584
[ "The", "shorter", "C-terminal", "peptide", "of", "isoform", "NF-ATc/B", "exerts", "a", "suppressive", "transcriptional", "effect", "." ]
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6585
[ "These", "properties", "of", "NF-ATc/B", "and", "-C", "might", "be", "of", "importance", "for", "gene", "regulation", "in", "naive", "T", "lymphocytes", "in", "which", "NF-ATc/B", "and", "-C", "are", "predominantly", "synthesized", "." ]
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6586
[ "Selection", "and", "long-term", "persistence", "of", "reactive", "CTL", "clones", "during", "an", "EBV", "chronic", "response", "are", "determined", "by", "avidity", ",", "CD8", "variable", "contribution", "compensating", "for", "differences", "in", "TCR", "affinities", "." ]
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6587
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6588
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6589
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6590
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6591
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[ "We", "found", "a", "wide", "range", "of", "TCR", "affinities", "among", "the", "different", "clonotypes", "that", "segregated", "with", "Vbeta", "usage", "." ]
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6594
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6595
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6596
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6597
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