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15801
[ "The", "v-erb", "A", "oncogene", "of", "avian", "erythroblastosis", "virus", "is", "a", "mutated", "and", "virally", "transduced", "copy", "of", "a", "host", "cell", "gene", "encoding", "a", "thyroid", "hormone", "receptor", "." ]
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15802
[ "The", "protein", "expressed", "by", "the", "v-erb", "A", "oncogene", "binds", "to", "DNA", "and", "acts", "as", "a", "dominant", "negative", "inhibitor", "of", "both", "the", "thyroid", "hormone", "receptor", "and", "the", "closely", "related", "retinoic", "acid", "receptor", "." ]
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15803
[ "The", "v-erb", "A", "protein", "has", "sustained", "two", "amino", "acid", "alterations", "within", "its", "DNA-binding", "domain", "relative", "to", "that", "of", "c-erb", "A", ",", "one", "of", "which", ",", "at", "serine", "61", ",", "is", "known", "to", "be", "important", "for", "v-erb", "A", "function", "in", "the", "neoplastic", "cell", "." ]
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15804
[ "We", "report", "here", "that", "the", "second", "alteration", ",", "at", "threonine", "78", ",", "also", "plays", "an", "important", ",", "although", "more", "indirect", ",", "role", ":", "alteration", "of", "the", "sequence", "at", "threonine", "78", "such", "that", "it", "resembles", "that", "of", "c-erb", "A", "can", "act", "as", "an", "intragenic", "suppressor", "and", "can", "partially", "restore", "function", "to", "a", "v-erb", "A", "protein", "rendered", "defective", "due", "to", "a", "mutation", "at", "position", "61", "." ]
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15805
[ "Threonine", "78", "lies", "within", "the", "D-box", "of", "the", "v-erb", "A", "protein", ",", "a", "region", "thought", "to", "mediate", "receptor-receptor", "dimerizations", ",", "and", "is", "not", "in", "physical", "proximity", "to", "the", "serine", "at", "position", "61", "." ]
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15806
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15807
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15808
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15809
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15810
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15811
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15812
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15813
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15814
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15815
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15816
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15817
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15818
[ "It", "also", "bound", "to", "the", "purine-rich", "CD3R", "element", "from", "the", "human", "immunodeficiency", "virus", "type", "2", "long", "terminal", "repeat", ",", "which", "is", "required", "for", "inducible", "virus", "expression", "in", "response", "to", "signalling", "through", "the", "T-cell", "receptor", "." ]
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15819
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15820
[ "Binding", "of", "erythroid", "and", "non-erythroid", "nuclear", "proteins", "to", "the", "silencer", "of", "the", "human", "epsilon-globin-encoding", "gene", "." ]
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15821
[ "To", "clarify", "the", "molecular", "mechanisms", "involved", "in", "the", "developmental", "control", "of", "hemoglobin-encoding", "genes", "we", "have", "been", "studying", "the", "expression", "of", "these", "genes", "in", "human", "cells", "in", "continuous", "culture", "." ]
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15822
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15823
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15824
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15825
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15826
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15827
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15828
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15829
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15830
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15831
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15832
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15833
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15834
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15835
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15836
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15837
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15838
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15840
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15849
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15850
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15852
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15855
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15857
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15858
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15859
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15860
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15861
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15863
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15864
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15865
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15866
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15867
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15868
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15869
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15870
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15871
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15872
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15873
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15874
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15875
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15876
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15877
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15878
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15879
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15880
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15881
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15882
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15883
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15884
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15885
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15886
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15887
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15888
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15889
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15890
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15891
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15892
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15893
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15894
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15895
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15896
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15897
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15898
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15899
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15900
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