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10101
[ "NGAL", "was", "expressed", "in", "bone", "marrow", "and", "in", "tissues", "that", "are", "prone", "to", "exposure", "to", "microorganisms", "." ]
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10102
[ "Potential", "cis-acting", "elements", "were", "identified", "in", "the", "promoter", "region", "of", "the", "NGAL", "gene", "by", "computer", "analysis", "and", "include", "binding", "sites", "for", "CTF/CBP", ",", "the", "hematopoietic", "transcription", "factors", "GATA-1", "and", "PU.1", ",", "and", "the", "LPS-inducible", "factor", "NF-kappa", "B", "." ]
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10103
[ "Human", "neutrophils", "express", "GH-N", "gene", "transcripts", "and", "the", "pituitary", "transcription", "factor", "Pit-1b", "." ]
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10104
[ "Since", "GH", "stimulates", "the", "development", "and", "function", "of", "granulocytes", ",", "we", "investigated", "the", "expression", "of", "GH", "in", "granulocyte", "subsets", "." ]
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10105
[ "By", "immunocytochemistry", ",", "25", "+/-", "7", "%", "of", "the", "human", "neutrophils", "were", "shown", "to", "express", "immunoreactive", "GH", ",", "whereas", "eosinophils", "were", "negative", "." ]
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10106
[ "Reversed", "transcription", "(", "RT", ")", "-PCR", "analysis", "demonstrated", "GH", "mRNA", "in", "neutrophils", "." ]
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10107
[ "Restriction", "analysis", "revealed", "that", "neutrophils", "express", "the", "GH-N", "gene", "but", "not", "the", "GH-V", "gene", "." ]
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10108
[ "Furthermore", ",", "we", "demonstrated", "by", "western", "blot", "analysis", "that", "neutrophils", "express", "an", "alternatively", "spliced", "variant", "of", "the", "pituitary", "transcription", "factor", "Pit-1", ",", "designated", "Pit-1b", "." ]
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10109
[ "The", "ability", "of", "BHRF1", "to", "inhibit", "apoptosis", "is", "dependent", "on", "stimulus", "and", "cell", "type", "." ]
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10110
[ "The", "development", "of", "resistance", "to", "host", "defense", "mechanisms", "such", "as", "tumor", "necrosis", "factor", "(", "TNF", ")", "-", "and", "Fas-mediated", "apoptosis", "of", "transformed", "or", "virus-infected", "cells", "may", "be", "a", "critical", "component", "in", "the", "development", "of", "disease", "." ]
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10111
[ "To", "find", "genes", "that", "protect", "cells", "from", "apoptosis", ",", "we", "used", "an", "expression", "cloning", "strategy", "and", "identified", "BHRF1", ",", "an", "Epstein-Barr", "virus", "(", "EBV", ")", "early-lytic-cycle", "protein", "with", "distant", "homology", "to", "Bcl-2", ",", "as", "an", "anti-apoptosis", "protein", "." ]
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10112
[ "Expression", "of", "BHRF1", "in", "MCF-Fas", "cells", "conferred", "nearly", "complete", "resistance", "against", "both", "anti-Fas", "antibody", "and", "TNF-mediated", "apoptosis", "." ]
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10113
[ "In", "addition", ",", "BHRF1", "protected", "these", "cells", "from", "monocyte-mediated", "killing", "but", "failed", "to", "protect", "them", "from", "killing", "mediated", "by", "lymphokine-activated", "killer", "cells", "." ]
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10114
[ "The", "ability", "of", "BHRF1", "to", "protect", "MCF-Fas", "cells", "from", "apoptosis", "induced", "by", "various", "stimuli", "was", "identical", "to", "that", "of", "Bcl-2", "and", "Bcl-xL", "." ]
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10115
[ "Moreover", ",", "the", "mechanism", "of", "action", "of", "BHRF1", "resembled", "that", "of", "Bcl-2", "and", "Bcl-xL", "as", "it", "inhibited", "TNF-", "and", "anti-Fas-induced", "activation", "of", "two", "enzymes", "participating", "in", "the", "apoptosis", "pathway", ",", "cytosolic", "phospholipase", "A2", "and", "caspase-3/CPP32", ",", "but", "did", "not", "interfere", "with", "the", "activation", "of", "NF-kappaB-like", "transcription", "factors", "." ]
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10116
[ "A", "putative", "function", "of", "BHRF1", "in", "EBV-infected", "epithelial", "cells", "may", "be", "to", "protect", "virus-infected", "cells", "from", "TNF-", "and/or", "anti-Fas-", "induced", "cell", "death", "in", "order", "to", "maximize", "virus", "production", "." ]
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10117
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10118
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10119
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10120
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10121
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10122
[ "We", "here", "describe", "the", "genomic", "organisation", "(", "3", "exons", "of", "132", ",", "112", "and", "542", "bp", "and", "2", "introns", "of", "1211", "and", "378", "bp", ")", "and", "sequence", "including", "3", "kb", "of", "DNA", "from", "the", "immediate", "5", "'", "upstream", "region", "of", "the", "human", "eotaxin", "gene", "." ]
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10123
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10124
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10125
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10126
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10127
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10128
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10129
[ "All", "these", "motifs", "are", "essential", "and", "collectively", "control", "transcriptional", "activity", "." ]
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10130
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10131
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10132
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10133
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10134
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10135
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10136
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10137
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10138
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10139
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10140
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10141
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10142
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10143
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10144
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10145
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10146
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10147
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10148
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10149
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10150
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10151
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