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4,900
We and others have characterized the biochemistry of serum-derived sMHC and shown quantitative differences between individuals of different human leukocyte antigen (HLA) haplotypes [4–7].
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background
4,901
ISCA 2012 paper [66], simply adding more banks to the memory subsystem comes at signi cantly high costs or reduced performance regardless of the way it is done: more banks per chip, more ranks per channel, or more channels.
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background
4,902
These results differ from those of Goodman et al. (2002) but are in agreement with two other studies (Lachman et al., 1996; Syv√§nen et al., 1997).
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result
4,903
The PCR product was digested with AgeI/NotI and ligated between the G and the L gene (similar to Roberts et al., 1999) into the vectors pVSVCT-1 and pVSVCT-9 (Schnell et al., 1998), which had been digested with XmaI/NotI.
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method
4,904
Thirty-one additional bindin sequences of E. viridis and 16 of E. vanbrunti (accession numbers AY451276–AY451323, McCartney and Lessios 2004) were included in the analyses.
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method
4,905
EEG analyses the analyses of oscillatory activity were conducted according to previously published methods (e.g., see arzy et al. 2010; Bernasconi et al. 2011).
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method
4,906
Because the doses of labeled caffeine were adjusted to body weight, the 13C enrichment values were recorded without body weight normalization [14].
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background
4,907
A recently proposed criterion selects the cut-point maximizing the classification concordance probability, which is equivalent to a product of the associated sensitivity and specificity [6].
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background
4,908
Other studies, on the contrary, reported opposite results, supporting a link between beta-cell function and long-term complications [9,10], which may be exerted indirectly, through better metabolic control [9,13].
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result
4,909
This is comparable to results obtained by GonzaÃÅlez Benito et al. (1997), who conducted laboratory batch tests to determine the ability of Trametes versicolor to treat molasses-based distillery wastewater.
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result
4,910
Data Centric Storage (DCS) [24, 27, 42, 56] is a prominent data-storage and queryprocessing mechanism on Wireless Sensor Networks (WSNs).
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background
4,911
The Index was developed by Zill and Peterson, based on numerous preexisting instruments (Achenbach & Edelbrock, 1981; Graham & Rutter, 1968a; Kellam, Branch, Agorwal, & Ensminger, 1975; Langner et al., 1976; Rutter, Tizard, & Whitmore, 1970; National Center for Health Statistics, 1971).
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background
4,912
Trials were considered eligible if they satisfied the following inclusion criteria: (1) RCTs comparing RIC versus no conditioning in patients with AMI; (2) patients were treated by primary PCI or thrombolysis; (3) RIC was induced by intermittent limb ischemia–reperfusion; and (4) trials at least reported one of the following outcome measures, including enzymatic myocardial infarction size as assessed by serum peak creatine
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method
4,913
This is a puzzling finding, for in the barn owl, with its excellent high frequency hearing, there are no ‘tall’ hair cells in the basal half of the papilla (Smith et al., 1985).
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background
4,914
While serum glucose was estimated by the modified glucose oxidase method, using GOD-POD kits (Glaxo India Ltd, Mumbai, India); for the hepatic LPO, SOD, CAT and GSH routine protocols, followed earlier in our laboratory, were used (Jatwa and Kar, 2006; Panda and Kar, 2006).
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method
4,915
Morphometrical analysis for villous height, crypt depth, villous width, epithelial surface area, and villous compartment volume was done as described elsewhere [18], but only the first 2 measurements were taken for biopsy samples obtained after baseline.
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method
4,916
In addition, it was shown before that domain I is necessary for the degradation of the substrates (23, 27).
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background
4,917
For definition of infection we used criteria provided by the Guideline for Prevention of Surgical Site Infection (SSI), which distinguishes between superficial incisional SSI, deep incisional SSI and organ/space SSI [13].
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method
4,918
Molecular, anatomical and behavioural characteristics of GR-i mice As previously reported (Froger et al. 2004 ; Holsboer & Barden, 1996 ; Pepin et al. 1992), genome incorporation of the transgene encoding GR antisense RNA downregulated GR expression in GR-i mice.
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background
4,919
Trait data collection We used 10 plant functional traits related to growth, survival, and the response to environmental change (Pérez-Harguindeguy et al. 2013), including leaf area (LA; mm2), specific leaf area (SLA; mm2 g 1), chlorophyll content (measured by the SPAD device unit [see below]),…
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method
4,920
Beuschlein et al. (2013) identified somatic mutations in the ATP1A1 gene encoding Na+/K+ ATPase α subunit and the ATP2B3 gene encoding Ca2+ ATPase in APA, which are genes involved in regulating sodium, potassium, and calcium ion homeostasis.
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background
4,921
We have implemented our ideas in the LLVM [28] compilation infrastructure, and have used this implementation to improve the effectiveness of Polly-LLVM [17], a loop-optimizer used in tandem with that compiler.
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method
4,922
Since many of the interactions come from highthroughput studies and since such studies are known to have numerous false positives, we applied the method of Goldberg and Roth [62] to estimate the reliability of each PPI.
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method
4,923
The study reporting a 40% specificity included only five disease negative patients [24]; in contrast to larger disease free cohorts [23,31] reporting specificities of up to 98.
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result
4,924
In France, the SCID (the Structured Clinical Interview for DSM-IV [22]) was used to identify schizophrenia.
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method
4,925
However, several lignin-degrading white-rot fungi seem to operate ligninolysis without expressing detectable ligninase activity (Sannia et al. 1991; Garzillo et al. 1992; Srebotnik et al. 1994; Eggert et al. 1996b, 1997).
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background
4,926
Staffing measures used in previous studies include nurse full-time equivalents (FTEs), nursing hours per patient day (HPPD), registered nurse (RN) skill mix, nurse-to-patient ratios, and nurseperceived staffing adequacy (Aiken et al., 2002; Schmalenberg and Kramer, 2009; Unruh et al., 2009).
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background
4,927
2013), whereas with the overexpression of the strawberry FaMYB1, it is shared only the down-regulation of ANS/ LDOX (Aharoni et al. 2001).
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background
4,928
Several authors have reported Cx43 modulation in human diseases related to poor skin healing, such as hypertrophic scars and keloids [11] or in wounds of diabetic patients [32,33].
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background
4,929
The electrostatic surface representations of the CRV-ZWE-157 protein structure and the DRBP template were produced by the Adaptive Poisson-Boltzmann Solver (APBS) plugin [43] in PyMOL [44] List of Abbreviations aa: amino acid; APBS: Adaptive Poisson-Boltzmann Solver; BLASTp: Basic local alignment search tool protein; CRV: Crocodilepox virus; CRV-ZWE: Crocodilepox virus strain Zimbabwe; DGCR8: DiGeorge syndrome critical region gene 8; DRBP: double-stranded RNA-binding proteins; dsRNA: doublestranded RNA; KSDSSP: Kabsch and Sander algorithm for defining the secondary structure of proteins; MCV: Molluscum contagiosum virus; MSA: Multiple sequence alignments; MUSCLE: multiple sequence comparison by log-expectation; NCBI: National Center for Biotechnology Information; PSIBLAST: Position specific iterated-BLAST; RMSD: Root mean square deviation; RNAi: RNA interference; TRBP: TAR RNA Binding Protein; VACV: Vaccinia virus; VBRC: Viral bioinformatics resource center; VOCs: Viral Orthologous Clusters Acknowledgements This work was funded by a Canadian NSERC Discovery grant.
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method
4,930
Recently, an ansatz for D = 11 FS spacetimes corresponding to M5-branes wrapping SLAG cycles of a Calabi-Yau 3-fold has been constructed [29] using the G-structures approach [30, 31, 32, 33, 34].
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method
4,931
The remaining 10% were attributed to a diploid oocyte due to a failure in the first meiotic division (Jacobs et al., 1978).
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background
4,932
The cutting scores for TOMM and WMT were derived from the test manuals (Green, 2005; Tombaugh, 1995).
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method
4,933
4B, top) by using a method of adenovirus conjugated to poly-Llysine as described previously (15).
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method
4,934
Most recently, we identified 361 propionylation sites in 183 mid-exponential and late stationary phase proteins in Thermus thermophilus, an extremely thermophilic eubacterium (Okanishi et al. 2014), which was the first report showing the prevalence of post-translational lysine propionylation on diverse proteins.
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background
4,935
Interestingly, this meta-perceptual distinction between being (perceived to be) dehumanized and disliked parallels a similar distinction between dehumanizing and disliking, which have been shown to exert independent effects on intergroup outcomes (e.g., Andrighetto et al., 2014; Kteily et al., 2015).
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background
4,936
…kisspeptin was identified as a ligand for the orphan G-protein coupled receptor 54 (GPR54), which was first described in the rat brain and subsequently in human (then named AXOR12 and hOT7T175) (Lee et al., 1999; Muir et al., 2001; Ohtaki et al., 2001), now termed KISS1R (Gottsch et al., 2009).
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background
4,937
However, US and MW contrast strongly in protection levels, as US lacks law enforcement on the ground and therefore human disturbance is high (Rovero et al. 2012); 3) Matundu (MT) is the largest (526 km2) forest block in the Udzungwa range, and is predominantly lowland (280–1,000 m a.s.l.; Marshall…
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background
4,938
We elected to take this course because formal methods for analyzing the efficiency of move ordering strategies in the alpha-beta search are unreported in the literature [27, 30], and as a result, practical experimentation is the accepted form of analysis in the state-of-the-art [26].
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method
4,939
We then trained the unlexicalised parsers BitPar (Schmid, 2004) and LoPar (Schmid, 2000), and the Stanford parser (Klein and Manning, 2003) in its lexicalised and Markovised form14 on the training set and tested them on the 2000 test sentences as well as on the 200 TePaCoC sentences.
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method
4,940
The keyword search semantics on XML documents are mainly focus on the Lowest common ancestor (LCA) based semantics, including the LCA semantics and its variants [28–30,32,34,39] to improve the search quality.
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background
4,941
The FLNA(16-23) fragment was injected on immobilized ICL3 or ICL3ΔCt (FLNA negative control) prior to β-arr2 injection.
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method
4,942
In a previous publication (Dymkowska et al., 2006) we showed that arachidonic acid induced apoptosis in rat hepatoma AS-30D cells along with a drastic increase of the production of reactive oxygen species (ROS).
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background
4,943
If macros are considered to be critically important, it would be possible to replace them by function calls using demacrofication [76].
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background
4,944
The term lesser known species does not imply that the species are unknown, but rather they presently constitute the bulk of wood that finds no economic use (Barany et al. 2003).
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background
4,945
These results are consistent with results from prior studies of normal personality traits during different periods in adulthood which suggest that genetic influences are stable over time (McGue et al. 1993; Johnson et al. 2005; Kandler et al. 2010).
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result
4,946
Eicosanoids can have potent biological affects that include modulation of cellular replication and sensitivity to apoptosis.(33,40) Their production is dependent on expression of specific enzymes and the relative abundance of PUFA substrate, which we clearly modified with our experimental diets.
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background
4,947
As shown in the simulation studies in Bartroff and Lai (2008) and in the asymptotic theory in Section 4, this approach yields adaptive tests that are comparable to the benchmark optimal adaptive test of Jennison and Turnbull (2006a,b) for a normal mean, which assumes known variance and a specified…
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result
4,948
Further evidence that tyrosine phosphorylation targets functionally important residues includes modification of the response regulator PhoP switch residue Tyr98 [41] and SspA Tyr92, which protrudes from a surface-exposed pocket and is critical for activity [42].
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background
4,949
Macrophages and polymorphonuclear cells present at the site of synovitis promotes the formation of reactive oxygen species and subsequent activation of inflammatory molecules which are involved in the progression of RA [4].
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background
4,950
Two prospective studies described combination therapy with EECI and balloon dilation: one each from Japan [11] and Germany [12].
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result
4,951
Interestingly, B. licheniformis fur (furBL) seems to have two independent PerR boxes suggesting that the regulation of furBL by PerRBL may be different from that of B. subtilis fur which has only one PerR box sequence in the promoter region (Fuangthong et al., 2002).
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background
4,952
To quantify the difference between these patterns, we calculated the difference in perceived locations of the 4th and 5th click-pairs, a procedure introduced by Hari and Kiesilä (1996).
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method
4,953
Recognized risk factors that may account for the occurrence and severity of radiation retinopathy, especially in cases following low dosages, include diabetes mellitus and chemotherapy.(8,9) Systemic hypertension may also be a risk factor in some cases.
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background
4,954
We used expert consensus to identify Diagnosis Related Group (DRG), Current Procedural Terminology (CPT), and ICD9-CM codes relevant to diabetic foot conditions to adapt the classification scheme of the IWG on the diabetic foot.(8) The risk categories were then ordered by severity into levels from 0 (lowest, with no codes of interest) to 6 (highest).
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method
4,955
Neuropsychological test variables used in the present analyses include Mini-Mental State Examination (MMSE) [35], Clinical Dementia Rating scale global & sum of boxes scores [36], Category Fluency (animal naming), Trailmaking tests A & B, WAIS Digit-Symbol substitution, Wechsler Logical Memory delayed recall, and the Wechsler Adult Intelligence Scale-revised (WAIS-R) forward and reverse digit span tests.
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method
4,956
For example, NusA binds reversibly to RNAP in affecting pausing and termination (120) but is believed to bind irreversibly in an antitermination complex with N (8, 45) or Q of bacteriophage 82 (82Q) (126).
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background
4,957
…including slope of the landscape and distance to road (Fortin et al. 2005), habitat diversity (Boyce, Mao & Merrill 2003), habitat openness (e.g. Creel & Winnie 2005; Proffitt et al. 2009), snowpack and elk density (e.g. Gower et al. 2009; Proffitt et al. 2015), and predation risk from wolves…
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background
4,958
Genome-wide SNP genotyping for SHARP subjects was performed by Affymetrix, Inc. (Santa Clara, CA) using the Affymetrix Genome-Wide Human SNP Array 6.0.
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method
4,959
4%, an enormous improvement compared to the Lumbini survey 1995 result that reported just 15% [20, 24, 38].
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result
4,960
Cattle and sheep are thought to be the major reservoir of STEC, since the species often carry STEC in their intestinal flora and serve as a source of food contamination (Martins da Costa et al., 2011). There are some studies about the presence and prevalence of STEC and EPEC in healthy poultry feces and product. The results of the present study revealed the presence of two stx2 positive isolates, which were considered as STEC pathotype. On the other hand, 11% of the examined external and visceral cavity isolates were only positive for the eae gene, which were considered as EPEC strains. Moreover, one of the isolates possessed both stx2 and eae genes which is considered as highly pathogenic. This isolate belonged to phylo-groupD and phylo-subgroupD2. Salehi (2012) in Iranhas evaluated the presence of virulence factors in 290 fecal E.
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background
4,961
Deep pocket volumes of surface pockets at protein interaction sites harboring a bound inhibitor (red circles) and pockets found elsewhere on the protein surface (black x’s) are plotted against the corresponding pocket volumes identified by Q-SiteFinder, for each of the sites used in Figure 1B.
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method
4,962
The next section recaptures some basic results on multifractal products of stochastic processes as developed in Kahane (1985), Kahane (1987) and Mannersalo et al (2002).
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background
4,963
The knee extensor force was thus registered through the axis of the load cell perpendicular to the shank (39,46).
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background
4,964
The HIR complex has been reported to interact with SWI/SNF and is necessary for the recruitment of SWI/SNF to the histone genes [22].
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background
4,965
Hogan, et al also showed that literacy was the most important factor in increasing contraceptive knowledge and the desire to limit or space births (31).
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background
4,966
All participants were randomised in the included trials, however, only four studies [32–35] specified the method used, one of which [33] described randomisation by sequential allocation according to age (and symptom duration) a method deemed inappropriate by van Tulder et al.
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result
4,967
(4) Severe oxygenation failure: PaO2/FIO2 of less than 150 mmHg or intrapulmonary shunt 20% or greater while on positive end-expiratory pressure (PEEP) of 12 cm H2O or greater, with PAOP of less than 18 mmHg, and chest roentgenograph with infiltrates.
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background
4,968
Inclusion criteria were [9, 14, 15]: (1) All the patients had undergone total resection and were confirmed to be HGG by pathology.
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background
4,969
We use one stage face detector with main bone of ZF-net [34], VGG CNN M 1024 [3], VGG16 [25] and ZF-24-net.
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method
4,970
Random transposon mutagenesis by TnYLB-1 The mutagenesis was preformed according to Le Breton et al., 2006 [92].
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method
4,971
Language Stream In our experiments, we apply the GoogleNet [36] with batch normalization [44] as image encoder and CNN-RNN [34] as text encoder.
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method
4,972
Investigations of the intact animal and of reduced abdominal preparations have shown that the force generated by the reflex can widely vary (Krans and Chapple 2005).
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4,973
We previously reported that oxidative DNA damage in chondrocytes accumulates in the degenerated articular cartilage in OA, reducing its maintenance potential [4].
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4,974
An interpretative approach [18] is used to gain a better understanding of the mechanisms influencing the development of electronic co-operation tools in the healthcare sector.
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method
4,975
Increasing evidence suggests that the CaSR, a G protein-coupled receptor, plays an important role in controlling divalent cation reabsorption in the renal tubule in health and disease (Riccardi & Brown, 2010; Riccardi & Kemp, 2012).
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4,976
responsive elements (GREs), and indirectly, through suppression of other transcription factors (eg, NF-jB); and these mechanisms are relevant to GC efficacy and possibly side effects in DMD.(30,31) The SPP1 promoter is predicted to contain both GREs and NF-jB–responsive sites, and further studies are needed to dissect these mechanisms both in vitro and in vivo.
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4,977
One way to understand these algorithms is to view their cost functions as free-energy functions from statistical physics (Yedidia et al., 2004; Heskes, 2003).
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4,978
GATA4 is a critical transcription factor of most cardiacexpressed structural genes and hypertrophy-related genes, including the atrial natriuretic peptide (ANP) gene [13,14].
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4,979
Parke’s (1999) Error Duration Model contains long memory exclusively at the zero frequency.
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4,980
Once in aquatic environments, inorganic Hg is microbiologically transformed to MeHg (Anderson et al. 2004; Zahir et al. 2005), making it more prone to biomagnification (Zahir et al. 2005).
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4,981
An SVC is equivalent to a shunt capacitor and a shunt reactor that can be adjusted to control the voltage and reactive power at its terminals in a prescribed manner [9].
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4,982
On the other hand, whereas the benchmark optimal adaptive test needs to assume a specified alternative, these adaptive two-stage tests and the adaptive tests of Bartroff and Lai (2008) do not require such assumptions as they consider the estimated alternative at the end of the first stage.
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4,983
To analyze the stability of such a multi-agent system, there are many possible approaches, such as the frequency domain approach (Olfati-Saber & Murray, 2004), the Lyapunov-based approach (Chopra & Spong, 2006; Hong et al., 2008; Lin et al., 2008; Liu & Passino, 2006; Olfati-Saber & Murray, 2004;…
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method
4,984
In this article, we report absolute measurements of the optical coefficients of two-layered media that expand on our previous work on multi-distance absolute measurements on tissue-like phantoms [66], animal brain [35,51], and human brain [37].
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4,985
Transient expression of antibody fragments in tobacco leaves The system for transient expression in tobacco was based on MagnICON‚Ñ¢ vectors from Icon Genetics GmbH (Halle, Germany) [60,61].
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method
4,986
These observations confirm previous results from our team [53] who reported that an early reduction of CgA levels within 3 months from treatment (either surgical or systemic) can anticipate favourable prognosis.
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result
4,987
GFP fluorescence of COS7 cells expressing GFP-COQ7 and the deletion mutants GFPCOQ7(11-217), lacking amino acids 1-10, and GFP-COQ7(30-217), lacking amino acids 1-29.
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4,988
Some investigations did not find any association of statin use with anti-cancer effects on bladder cancer, while others suggested that statins increase the risk of bladder cancer [10,11].
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4,989
…traditionally put forward as a major biological factor facilitating herbivory and frugivory in lizards (see Schoener et al. 1982; Van Damme 1999; Cooper and Vitt 2002), a recent review of frugivory and seed dispersal by lizards suggested that frugivory should be considered an island phenomenon,…
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4,990
Aedes aegypti is a poikilothermic species; therefore, changes in response to environmental factors such as humidity, temperature and rainfall can affect the genetic structure of its populations [52,53].
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4,991
By contrast, 3H-forskolin, which labels the G,-adenylate cyclase complex (Seamon et al., 1984), shows pronounced density in the molecular layer of the cerebellum without labeling the deep nuclei (Worley et al., 1986b).
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4,992
Prothrombotic disorders were present in 11 children: antiphospholipid antibodies (n=5) [21, 31, 32, 36]; combined protein S deficiency and antiphospholipid antibodies (n=2) [36]; protein S deficiency (n=2) [16, 22]; protein C deficiency (n=1) [42]; heterozygote APC resistance (n=1) [26].
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4,993
Additionally, PTM sites possessing protein structures with modified residues were obtained from annotations on the PTM-SD database [19].
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method
4,994
Montreal WiFi Network: A co-location network for N = 103,425 users (nodes) of the Île Sans Fil free public wireless network in Montreal, Canada, where edges represent concurrent hotspot usage [56].
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4,995
These genes were further filtered through phylogenetic analysis alongwith previously known CSL proteins from Arabidopsis, Brachypodium, maize, and rice, which reflected some non-targeted genes that were removed from further analysis [26].
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method
4,996
Members of this family are present in animals from cnidarians to mammals and contain at least one cysteine-rich CABIT domain and a low-complexity proline-rich stretch (Chung et al., 2009; Johnson et al., 2009).
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4,997
This model is derived from the results obtained in [34], where the authors evaluate the rate-distortion curve for thousands of time series from real datasets that are compressed with lightweight algorithms typically adopted by resource-constrained sensors.
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method
4,998
A comparison between the findings of Krajcarski et al. (1999) and the rested values in the present study revealed similar effects of pre- load and added load on peak trunk flexion and extensor moments. The EMG activity of the trunk extensor muscles (TES and LES) had similar responses to the loading conditions, although the pre-trial LES and TES EMG amplitudes from Krajcarski et al. (1999) were about 6 to 13 %MVC larger than was found in the current study. Also, the peak muscle activity of the TES was about 10 %MVC lower and the IO and EO had larger EMG amplitudes during the pre-trial and trial in the Krajcarski et al. (1999) study.
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4,999
…semi- or nonparametric frontier models have been developed (e.g., Simar, 1992; Park and Simar, 1994; Fan et al., 1996; Kneip and Simar, 1996; Park et al., 1998, 2003, 2006; Post et al., 2002; Griffin and Steel, 2004; Henderson and Simar, 2005; Kuosmanen et al., 2007; and Kumbhakar et al., 2007).
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