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Vision declined after treatment with methylprednisolone, after which fundus examination became consistent with progressive outer retinal necrosis. | [
{
"ade": "Vision declined",
"drug": "methylprednisolone"
}
]
|
Such a case induced by hypothyroidism complicating long-term therapy with amiodarone in a 45 year old woman with pre-excitation is presented. | [
{
"ade": "hypothyroidism",
"drug": "amiodarone"
}
]
|
Cardiac arrest after esmolol administration: a review of acute beta-blocker toxicity. | [
{
"ade": "Cardiac arrest",
"drug": "esmolol"
}
]
|
Pamidronate therapy should be considered in patients with hypercalcemia secondary to acute vitamin D poisoning. | [
{
"ade": "hypercalcemia",
"drug": "vitamin D"
},
{
"ade": "acute vitamin D poisoning",
"drug": "vitamin D"
}
]
|
OBJECTIVE: To determine the frequency of weight loss in patients treated with leflunomide for rheumatoid arthritis at an arthritis referral center. | [
{
"ade": "weight loss",
"drug": "leflunomide"
}
]
|
Because psoralens sensitize skin to ultraviolet A light, phototoxic reactions are the most frequent adverse effect of this treatment. | [
{
"ade": "phototoxic reactions",
"drug": "psoralens"
}
]
|
A case of tuberculosis in a patient on Efalizumab and Etanercept for treatment of refractory palmopustular psoriasis and psoriatic arthritis. | [
{
"ade": "tuberculosis",
"drug": "Etanercept"
},
{
"ade": "tuberculosis",
"drug": "Efalizumab"
}
]
|
We report 4 patients, 2 on methylphenidate and 2 on dextroamphetamine who presented with acral cyanosis, livedo reticularis, or Raynaud phenomenon. | [
{
"ade": "Raynaud phenomenon",
"drug": "dextroamphetamine"
},
{
"ade": "Raynaud phenomenon",
"drug": "methylphenidate"
},
{
"ade": "acral cyanosis",
"drug": "methylphenidate"
},
{
"ade": "acral cyanosis",
"drug": "dextroamphetamine"
},
{
"ade": "livedo reticularis",
"drug": "methylphenidate"
},
{
"ade": "livedo reticularis",
"drug": "dextroamphetamine"
}
]
|
We report a case of myoclonus induced by quetiapine. | [
{
"ade": "myoclonus",
"drug": "quetiapine"
}
]
|
Acute myocardial infarction during high-dose methylprednisolone therapy for Graves' ophthalmopathy. | [
{
"ade": "Acute myocardial infarction",
"drug": "methylprednisolone"
}
]
|
Lithium treatment was terminated in 1975 because of lithium intoxication with a diabetes insipidus-like syndrome. | [
{
"ade": "lithium intoxication",
"drug": "lithium"
},
{
"ade": "diabetes insipidus-like syndrome",
"drug": "lithium"
},
{
"ade": "lithium intoxication",
"drug": "Lithium"
},
{
"ade": "diabetes insipidus-like syndrome",
"drug": "Lithium"
}
]
|
Localized panniculitis and subsequent lipoatrophy with subcutaneous glatiramer acetate (Copaxone) injection for the treatment of multiple sclerosis. | [
{
"ade": "Localized panniculitis",
"drug": "Copaxone"
},
{
"ade": "lipoatrophy",
"drug": "Copaxone"
},
{
"ade": "Localized panniculitis",
"drug": "glatiramer acetate"
},
{
"ade": "lipoatrophy",
"drug": "glatiramer acetate"
}
]
|
Amiodarone-induced thyrotoxicosis associated with thyrotropin receptor antibody. | [
{
"ade": "thyrotropin receptor antibody",
"drug": "Amiodarone"
},
{
"ade": "thyrotoxicosis",
"drug": "Amiodarone"
}
]
|
We report on a patient with subarachnoid haemorrhage who developed an acute life-threatening pseudo-obstruction of the colon, a variant of adynamic ileus, while being treated with intravenous nimodipine. | [
{
"ade": "adynamic ileus",
"drug": "nimodipine"
},
{
"ade": "pseudo-obstruction of the colon",
"drug": "nimodipine"
}
]
|
Heat stroke-like episode in a child caused by zonisamide. | [
{
"ade": "Heat stroke-like episode",
"drug": "zonisamide"
}
]
|
Emergence of Philadelphia positive chronic myeloid leukaemia during treatment with hydroxyurea for Philadelphia negative essential thrombocythaemia. | [
{
"ade": "Philadelphia positive chronic myeloid leukaemia",
"drug": "hydroxyurea"
}
]
|
Heparin-induced thrombocytopenia is a rare and serious complication of anticoagulation therapy. | [
{
"ade": "thrombocytopenia",
"drug": "Heparin"
}
]
|
Lithium neurotoxicity should be considered in Creutzfeldt-Jakob disease differential diagnosis, serial electroencephalograms being the most valuable. | [
{
"ade": "Lithium neurotoxicity",
"drug": "Lithium"
},
{
"ade": "Creutzfeldt-Jakob disease",
"drug": "Lithium"
}
]
|
It has been suggested that PPE caused by cytarabine does not recur with subsequent cytarabine re-challenge. | [
{
"ade": "PPE",
"drug": "cytarabine"
}
]
|
Ten days after itraconazole was started, he developed paralytic ileus, neurogenic bladder, mild left ptosis, and absence of deep reflexes, with severe paralysis of the lower extremities and mild weakness of the upper extremities. | [
{
"ade": "mild left ptosis",
"drug": "itraconazole"
},
{
"ade": "absence of deep reflexes",
"drug": "itraconazole"
},
{
"ade": "severe paralysis of the lower extremities",
"drug": "itraconazole"
},
{
"ade": "paralytic ileus",
"drug": "itraconazole"
},
{
"ade": "neurogenic bladder",
"drug": "itraconazole"
},
{
"ade": "mild weakness of the upper extremities",
"drug": "itraconazole"
}
]
|
This case supports the view that in gold-induced pneumonitis a prolonged treatment with corticosteroids may be necessary, as lung function continued to improve. | [
{
"ade": "pneumonitis",
"drug": "gold"
}
]
|
Horner's syndrome and demyelinating peripheral neuropathy caused by high-dose cytosine arabinoside. | [
{
"ade": "demyelinating peripheral neuropathy",
"drug": "cytosine arabinoside"
},
{
"ade": "Horner's syndrome",
"drug": "cytosine arabinoside"
}
]
|
We have described three patients with hepatitis C for whom IFN-alpha and ribavirin were prescribed and who developed two successive phases of silent thyroiditis followed by hyperthryroidism relapse due to Graves' disease. | [
{
"ade": "thyroiditis",
"drug": "ribavirin"
},
{
"ade": "hyperthryroidism",
"drug": "ribavirin"
},
{
"ade": "thyroiditis",
"drug": "IFN-alpha"
},
{
"ade": "hyperthryroidism",
"drug": "IFN-alpha"
}
]
|
We report a case of acute generalized exanthematous pustulosis (AGEP) induced by salazosulfapyridine in a patient with ulcerative colitis. | [
{
"ade": "acute generalized exanthematous pustulosis",
"drug": "salazosulfapyridine"
}
]
|
L-asparaginase-induced pancreatitis has been reported during or closely following administration of the drug. | [
{
"ade": "pancreatitis",
"drug": "L-asparaginase"
}
]
|
A patient presented with a painful, oedematous, cyanosed hand having injected a solution of diamorphine and methylphenidate into his radial artery. | [
{
"ade": "painful, oedematous, cyanosed hand",
"drug": "diamorphine"
},
{
"ade": "painful, oedematous, cyanosed hand",
"drug": "methylphenidate"
}
]
|
Acute aluminum toxicity after continuous intravesical alum irrigation for hemorrhagic cystitis. | [
{
"ade": "aluminum toxicity",
"drug": "alum"
}
]
|
Visual system side effects caused by parasympathetic dysfunction after botulinum toxin type B injections. | [
{
"ade": "Visual system side effects",
"drug": "botulinum toxin type B"
},
{
"ade": "parasympathetic dysfunction",
"drug": "botulinum toxin type B"
}
]
|
Hypoxia is a predisposing factor for premature ductal closure and often occurs after maternal indomethacin therapy. | [
{
"ade": "premature ductal closure",
"drug": "indomethacin"
},
{
"ade": "Hypoxia",
"drug": "indomethacin"
}
]
|
A severe form of exophthalmos resulting from lithium therapy has not been described in the literature. | [
{
"ade": "exophthalmos",
"drug": "lithium"
}
]
|
To date, there have been few reports of visual disturbances associated with BTX-B use. | [
{
"ade": "visual disturbances",
"drug": "BTX-B"
}
]
|
Flurbiprofen-associated acute tubulointerstitial nephritis. | [
{
"ade": "acute tubulointerstitial nephritis",
"drug": "Flurbiprofen"
}
]
|
Despite administration of phenytoin and lorazepam, the seizures persisted and occurred only during amphotercin B administration. | [
{
"ade": "seizures",
"drug": "amphotercin B"
}
]
|
Pregabalin-induced cortical negative myoclonus in a patient with neuropathic pain. | [
{
"ade": "cortical negative myoclonus",
"drug": "Pregabalin"
}
]
|
Acute renal failure during lisinopril and losartan therapy for proteinuria. | [
{
"ade": "Acute renal failure",
"drug": "losartan"
},
{
"ade": "Acute renal failure",
"drug": "lisinopril"
}
]
|
From these data, acute generalized dystonia with brainstem and thalamic lesions may occur in WD patients after an initial d-penicillamine therapy. | [
{
"ade": "acute generalized dystonia",
"drug": "d-penicillamine"
},
{
"ade": "brainstem and thalamic lesions",
"drug": "d-penicillamine"
}
]
|
OBJECTIVE: The purpose of this study was to report the concomitant occurrence of multiple squamous cell carcinomas and diffuse nail hyperpigmentation associated with hydroxyurea treatment, and to describe a successful therapeutic approach using imiquimod 5%. | [
{
"ade": "multiple squamous cell carcinomas",
"drug": "hydroxyurea"
},
{
"ade": "diffuse nail hyperpigmentation",
"drug": "hydroxyurea"
}
]
|
Although the two local anesthetics usually do not cause methemoglobinemia, we suspect that the displacement of lidocaine from protein binding by bupivacaine, in combination with metabolic acidosis and treatment with other oxidants, was the reason for the development of methemoglobinemia. | [
{
"ade": "methemoglobinemia",
"drug": "lidocaine"
}
]
|
DISCUSSION: Phenolphthalein is the active ingredient in several over-the-counter laxative preparations and has only rarely been reported to cause TEN. | [
{
"ade": "TEN",
"drug": "Phenolphthalein"
}
]
|
Warfarin-associated bleeding generally is considered deleterious; however, in our patient it unmasked an early stage of colon cancer and thus may have saved the patient's life. | [
{
"ade": "bleeding",
"drug": "Warfarin"
}
]
|
After having received gemcitabine on day 1 of the second course, the patient developed dry cough, subfebrile temperatures and dyspnea within 48 h. | [
{
"ade": "dyspnea",
"drug": "gemcitabine"
},
{
"ade": "dry cough",
"drug": "gemcitabine"
},
{
"ade": "subfebrile temperatures",
"drug": "gemcitabine"
}
]
|
The male patient was treated with 225-mg/day clozapine and the time to the diagnosis of agranulocytosis was 6 weeks. | [
{
"ade": "agranulocytosis",
"drug": "clozapine"
}
]
|
We report a case of unintentional overdose of oral pilocarpine tablets that resulted in bradycardia, mild hypotension, and muscarinic symptoms in a patient with Sjogren's syndrome. | [
{
"ade": "mild hypotension",
"drug": "pilocarpine"
},
{
"ade": "muscarinic symptoms",
"drug": "pilocarpine"
},
{
"ade": "bradycardia",
"drug": "pilocarpine"
}
]
|
We presented the case of a patient who developed a cutaneous reaction induced by captopril with positive patch test. | [
{
"ade": "cutaneous reaction",
"drug": "captopril"
}
]
|
Captopril-related (and -induced?) asthma. | [
{
"ade": "asthma",
"drug": "Captopril"
}
]
|
Deepening of lid sulcus from topical bimatoprost therapy. | [
{
"ade": "Deepening of lid sulcus",
"drug": "bimatoprost"
}
]
|
We are concerned that the macular lesion was a retinal toxic effect of gentamicin because of the recent description of similar lesions occurring after the inadvertent intraocular injection of massive doses of this drug. | [
{
"ade": "macular lesion",
"drug": "gentamicin"
}
]
|
Skin necrosis is a rare complication of subcutaneous heparin therapy that usually occurs at injection sites. | [
{
"ade": "Skin necrosis",
"drug": "heparin"
}
]
|
We assume that rIFN-gamma induced the de novo development of SLE in our patient. | [
{
"ade": "SLE",
"drug": "rIFN-gamma"
}
]
|
We describe a case of life-threatening hyponatremia associated with sibutramine use in an obese woman. | [
{
"ade": "hyponatremia",
"drug": "sibutramine"
}
]
|
Gemcitabine therapy has been associated with radiation recall reactions when used in the treatment of carcinoma. | [
{
"ade": "radiation recall reactions",
"drug": "Gemcitabine"
}
]
|
Thalidomide was withdrawn from world markets in 1961 following recognition of its teratogenic effects. | [
{
"ade": "teratogenic effects",
"drug": "Thalidomide"
}
]
|
We report a premature infant who developed seizures associated with intraventricular administration of nafcillin and discuss the need for electroencephalographic monitoring of patients receiving intraventricular antibiotics. | [
{
"ade": "seizures",
"drug": "nafcillin"
}
]
|
In this case report, we have described a patient with Crohn's disease who developed subfulminant hepatitis B after the fourth infusion of infliximab due to an unrecognized HBs-antigen carrier state. | [
{
"ade": "subfulminant hepatitis B",
"drug": "infliximab"
}
]
|
Here we describe a patient with Crohn's disease who developed a severe infliximab infusion reaction (IIR), complicated 1 day later by severe swelling of the forearm and hand ipsilateral to the site of infliximab infusion. | [
{
"ade": "severe infliximab infusion reaction",
"drug": "infliximab"
},
{
"ade": "severe swelling of the forearm and hand ipsilateral",
"drug": "infliximab"
},
{
"ade": "IIR",
"drug": "infliximab"
}
]
|
Although no coagulation study was done and the Meckel's diverticulum is normally associated with bleeding, the particular intensity of the following hemorrhage may have been favored by metformin. | [
{
"ade": "hemorrhage",
"drug": "metformin"
}
]
|
There remains a paucity of information pertaining to alternative anticoagulation strategies for use during cardiopulmonary bypass concomitant with heparin-induced thrombocytopenia, especially in children. | [
{
"ade": "thrombocytopenia",
"drug": "heparin"
}
]
|
Lamotrigine toxicity secondary to sertraline. | [
{
"ade": "Lamotrigine toxicity",
"drug": "Lamotrigine"
},
{
"ade": "Lamotrigine toxicity",
"drug": "sertraline"
}
]
|
Potential mechanisms involved in the occurrence of ischemic colitis in patients receiving tegaserod are also discussed. | [
{
"ade": "ischemic colitis",
"drug": "tegaserod"
}
]
|
Children with acute lymphoblastic leukemia (ALL), treated with L-asparaginase are at risk for cerebral thrombosis or hemorrhage because of coagulation protein deficiencies. | [
{
"ade": "coagulation protein deficiencies",
"drug": "L-asparaginase"
},
{
"ade": "hemorrhage",
"drug": "L-asparaginase"
},
{
"ade": "cerebral thrombosis",
"drug": "L-asparaginase"
}
]
|
Three patients who had experienced neuroleptic-induced akathisia in the past reported that the symptoms of fluoxetine-induced akathisia were identical, although somewhat milder. | [
{
"ade": "akathisia",
"drug": "fluoxetine"
}
]
|
A case is presented in which a 68-year-old man became delirious after being withdrawn from a low dosage of alprazolam. | [
{
"ade": "delirious",
"drug": "alprazolam"
}
]
|
We report a case of a 60-year-old woman affected by squamous lung carcinoma, who developed paroxysmal supraventricular tachycardia during cisplatin and etoposide combination chemotherapy. | [
{
"ade": "paroxysmal supraventricular tachycardia",
"drug": "etoposide"
},
{
"ade": "paroxysmal supraventricular tachycardia",
"drug": "cisplatin"
}
]
|
Tacrolimus (FK506), an immunosuppressant, has been associated with mutism in adults after liver transplant. | [
{
"ade": "mutism",
"drug": "FK506"
},
{
"ade": "mutism",
"drug": "Tacrolimus"
}
]
|
Nabumetone-associated interstitial nephritis. | [
{
"ade": "interstitial nephritis",
"drug": "Nabumetone"
}
]
|
This is the first case of TMP-SMX-induced hypersensitivity syndrome associated with the reactivation of a latent viral infection. | [
{
"ade": "hypersensitivity syndrome",
"drug": "TMP-SMX"
}
]
|
OBJECTIVE: To report a case of colchicine-induced myopathy in a teenager with familial Mediterranean fever (FMF). | [
{
"ade": "myopathy",
"drug": "colchicine"
}
]
|
We report the case of a patient with increased cerebral cortical excitability following intoxication with flupirtine, a centrally acting analgesic and antispastic drug. | [
{
"ade": "increased cerebral cortical excitability",
"drug": "flupirtine"
}
]
|
We describe a patient who developed granulocytopenia and fever after taking dipyrone and discuss the available literature. | [
{
"ade": "granulocytopenia",
"drug": "dipyrone"
}
]
|
CASE SUMMARY: A 39-year-old white Jewish schizophrenic man treated with olanzapine developed an elevated serum CK concentration with a peak concentration of 4000 IU/L (normal < 230). | [
{
"ade": "elevated serum CK concentration",
"drug": "olanzapine"
}
]
|
We report a case of 48-year-old woman with seizure disorder on divalproex sodium (Depakote) who presented with dyspnea. | [
{
"ade": "dyspnea",
"drug": "Depakote"
},
{
"ade": "dyspnea",
"drug": "divalproex sodium"
}
]
|
A fatal pancytopenia occurred in a patient with an history of depression with hypomanic rebounds, admitted for a manic episode and treated with levomepromazine, diazepam and lithium carbonate. | [
{
"ade": "fatal pancytopenia",
"drug": "levomepromazine"
},
{
"ade": "fatal pancytopenia",
"drug": "diazepam"
},
{
"ade": "fatal pancytopenia",
"drug": "lithium carbonate"
}
]
|
Histological examination of the dacryolith suggested its derivation from breakdown products of adrenaline. | [
{
"ade": "dacryolith",
"drug": "adrenaline"
}
]
|
PURPOSE: To report two cases of acute endophthalmitis following intravitreal bevacizumab injection. | [
{
"ade": "acute endophthalmitis",
"drug": "bevacizumab"
}
]
|
CONCLUSION: Squamous metaplasia in these cases appears to be a consequence of progestin therapy. | [
{
"ade": "Squamous metaplasia",
"drug": "progestin"
}
]
|
We hypothesize that caffeine toxicity injured the muscle cells, which were fragile due to the potassium depletion induced by the coexisting hyponatremia, to result in unusually severe rhabdomyolysis. | [
{
"ade": "rhabdomyolysis",
"drug": "caffeine"
},
{
"ade": "potassium depletion",
"drug": "caffeine"
},
{
"ade": "coexisting hyponatremia",
"drug": "caffeine"
},
{
"ade": "caffeine toxicity",
"drug": "caffeine"
},
{
"ade": "injured the muscle cells",
"drug": "caffeine"
}
]
|
A case of sideroblastic anemia is presented in a patient with a left ventricular assist device drive-line infection who was receiving linezolid, an antibiotic used for serious infections with gram-positive organisms. | [
{
"ade": "sideroblastic anemia",
"drug": "linezolid"
}
]
|
Trimethoprim-sulfamethoxazole-induced aseptic meningitis. | [
{
"ade": "aseptic meningitis",
"drug": "Trimethoprim-sulfamethoxazole"
}
]
|
Subacute cholestatic hepatitis likely related to the use of senna for chronic constipation. | [
{
"ade": "Subacute cholestatic hepatitis",
"drug": "senna"
}
]
|
Review of the literature relating to methicillin-induced nephropathy suggests a hypersensitivity origin for this disorder, but immunologic and ultrastructural investigation to date has failed to elucidate pathogenesis. | [
{
"ade": "nephropathy",
"drug": "methicillin"
}
]
|
We believe this is the first report of myocardial infarction due to coronary spasm, demonstrated by angiography associated with L-thyroxine therapy. | [
{
"ade": "coronary spasm",
"drug": "L-thyroxine"
},
{
"ade": "myocardial infarction",
"drug": "L-thyroxine"
}
]
|
Thrombocytosis induced by enoxaparin has been reported as a rare adverse effect of this medication in adults. | [
{
"ade": "Thrombocytosis",
"drug": "enoxaparin"
}
]
|
The case demonstrates that hypersensitivity reaction to pranlukast and resultant ATIN is possible, and that periodic urine testing in patients receiving pranlukast should be considered. | [
{
"ade": "hypersensitivity reaction",
"drug": "pranlukast"
},
{
"ade": "ATIN",
"drug": "pranlukast"
}
]
|
We report a case of severe anemia, which responded well to steroid therapy, in a patient receiving IL-2 plus IFN-alpha for metastatic renal cell carcinoma. | [
{
"ade": "severe anemia",
"drug": "IFN-alpha"
},
{
"ade": "severe anemia",
"drug": "IL-2"
}
]
|
Disulfiram encephalopathy as a cause of the catatonia syndrome. | [
{
"ade": "encephalopathy",
"drug": "Disulfiram"
},
{
"ade": "catatonia syndrome",
"drug": "Disulfiram"
}
]
|
OBJECTIVE: To report a case of possible foscarnet-induced severe hypomagnesemia and other electrolyte disorders. | [
{
"ade": "electrolyte disorders",
"drug": "foscarnet"
},
{
"ade": "severe hypomagnesemia",
"drug": "foscarnet"
}
]
|
Physicians should be cognizant of this potential complication in patients receiving thalidomide or thalidomide-like drugs who present with fever and pulmonary infiltrates and fail to improve despite treatment with broad-spectrum antibiotics. | [
{
"ade": "fever",
"drug": "thalidomide"
},
{
"ade": "pulmonary infiltrates",
"drug": "thalidomide"
}
]
|
The authors describe a patient with hemiparesis who developed the syndrome of irreversible lithium-effectuated neurotoxicity (SILENT) while being treated with lithium for a manic episode. | [
{
"ade": "neurotoxicity",
"drug": "lithium"
}
]
|
CONCLUSION: Anterior ischemic optic neuropathy may complicate treatment with interferon alfa. | [
{
"ade": "Anterior ischemic optic neuropathy",
"drug": "interferon alfa"
}
]
|
Unique behavioral change with cinepazide in parkinsonism. | [
{
"ade": "behavioral change",
"drug": "cinepazide"
}
]
|
Severe bleomycin lung toxicity: reversal with high dose corticosteroids. | [
{
"ade": "lung toxicity",
"drug": "bleomycin"
}
]
|
Less common adverse events to dapsone include the idiosyncratic reactions of leukopenia and agranulocytosis, cutaneous eruptions, peripheral neuropathy, psychosis, toxic hepatitis, cholestatic jaundice, nephrotic syndrome, renal papillary necrosis, severe hypoalbuminemia without proteinuria, an infectious mononucleosis-like syndrome, and minor neurological and gastrointestinal complaints. | [
{
"ade": "minor neurological and gastrointestinal complaints",
"drug": "dapsone"
},
{
"ade": "severe hypoalbuminemia without proteinuria",
"drug": "dapsone"
},
{
"ade": "toxic hepatitis",
"drug": "dapsone"
},
{
"ade": "leukopenia",
"drug": "dapsone"
},
{
"ade": "peripheral neuropathy",
"drug": "dapsone"
},
{
"ade": "cutaneous eruptions",
"drug": "dapsone"
},
{
"ade": "an infectious mononucleosis-like syndrome",
"drug": "dapsone"
},
{
"ade": "agranulocytosis",
"drug": "dapsone"
},
{
"ade": "nephrotic syndrome",
"drug": "dapsone"
},
{
"ade": "psychosis",
"drug": "dapsone"
},
{
"ade": "renal papillary necrosis",
"drug": "dapsone"
},
{
"ade": "cholestatic jaundice",
"drug": "dapsone"
}
]
|
Tacrolimus-induced HUS: an unusual cause of acute renal failure in nephrotic syndrome. | [
{
"ade": "acute renal failure",
"drug": "Tacrolimus"
},
{
"ade": "HUS",
"drug": "Tacrolimus"
}
]
|
OBJECTIVE: To report the occurrence of acute cytolytic hepatitis in a patient exposed to pulse itraconazole therapy for 24 weeks and provide a concise review of the literature on cases of itraconazole-induced hepatitis. | [
{
"ade": "hepatitis",
"drug": "itraconazole"
},
{
"ade": "acute cytolytic hepatitis",
"drug": "itraconazole"
}
]
|
Avascular necrosis of the femoral head in patients with prostate cancer treated with cyproterone acetate and radiotherapy. | [
{
"ade": "Avascular necrosis of the femoral head",
"drug": "cyproterone acetate"
}
]
|
Captopril-induced bone marrow suppression in two cardiac patients with trisomy 21. | [
{
"ade": "bone marrow suppression",
"drug": "Captopril"
}
]
|
Glaucoma secondary to epithelial downgrowth and 5-fluorouracil. | [
{
"ade": "Glaucoma",
"drug": "5-fluorouracil"
}
]
|
The 3-week sulphasalazine syndrome strikes again. | [
{
"ade": "sulphasalazine syndrome",
"drug": "sulphasalazine"
}
]
|
This case represents the third example of erythroid aplasia associated with an anti-inflammatory agent and the first instance due to fenoprofen. | [
{
"ade": "erythroid aplasia",
"drug": "fenoprofen"
}
]
|
Fever and maculopapular rashes appeared at 10 days after phenytoin initiation, and then the drug was discontinued. | [
{
"ade": "maculopapular rashes",
"drug": "phenytoin"
},
{
"ade": "Fever",
"drug": "phenytoin"
}
]
|
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