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A lumbar epidural catheter was placed preoperatively for pain management.
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The potential development of SJS/TEN, a severe life-threatening illness, emphasizes the need for judicious use of TMP-Sx and close monitoring and follow-up for patients who were given TMP-Sx for SSTIs.
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A three-year old female Whippet was hospitalized due to a multiple fracture and displacement of the left scapula caused by a recent car accident.
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Successful treatment of oral lichen planus-like chronic graft-versus-host disease with topical tacrolimus: a case report.
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Minimal change nephrotic syndrome developing during postoperative interferon-beta therapy for malignant melanoma.
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Neutropenic enterocolitis and cecal perforation in acute lymphatic leukemia.
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The delirium was not affected by administration of alprazolam.
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In one case the patient's reason for attendance was to obtain further supplies of analgesics.
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A 59-y-old with a history of chronic renal failure on hemodialysis was diagnosed with herpes zoster and begun on 800 mg acyclovir 5 times daily.
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A case of a female with advanced squamous carcinoma of the vagina is presented.
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This investigational compound was employed in a 50-year-old patient with acute myelomonocytic leukemia complicated by prolonged, treatment-induced granulocytopenia and documented Aspergillus flavus sinusitis with signs of disseminated aspergillosis.
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Here we report ramipril-induced cutaneous vasculitis in a patient who required steroid therapy to control it.
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Sedation improved at least moderately in 5 of the patients and mildly in 1 after they began taking donepezil.
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Patients receiving amifostine who develop only fever should be evaluated for an adverse drug reaction, as well as for sepsis and fevers of neutropenia, and it may be necessary to discontinue the drug.
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The latent period of therapy-related MDS (t-MDS) from the time of diagnosis of ATL was approximately 35 months.
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Acute acoustic nerve palsy associated with vincristine therapy.
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A study of nineteen immunocompromised patients with extensive skin lesions caused by Pseudomonas aeruginosa with and without bacteremia.
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As levodopa abuse has only been described in patients with PD, it was suspected to be promoted by central dopamine depletion (with consequent sensitization of dopamine receptors).
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Although taxol has shown significant activity in advanced ovarian cancer, peripheral neuropathy is likely to become the major dose-limiting toxicity.
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Physicians should therefore be aware of its occurrence and carefully monitor serum levels of CPK, GOT and GPT during the treatment of diabetes insipidus with clofibrate, especially in patients with associated hypothyroidism, latent or overt, which possibly favors the development of myopathy.
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Recurrent hypotension immediately after seizures in nortriptyline overdose.
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Fungal septicaemia is a serious and potentially fatal condition.
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An MRI showed T2 signal change in the conus medullaris gray matter at T11-12, consistent with an acute vascular infarct.
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Drug-resistant tuberculosis after gastrectomy.
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Sirolimus-eluting stent thrombosis several years after clopidogrel discontinuation.
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In some cases, removal of the necrotic tissue may be necessary to cure the infection.
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To our knowledge, this is the first case of polymyositis associated with dilated cardiomyopathy after the administration of interferon in a patient with hepatitis B.
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These cases illustrate a previously unrecognized and potentially causal relationship between tumor necrosis factor-alpha inhibition and reactivation of latent melanoma.
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CASE HISTORY: A 6-year-old white boy with a history of developmental delay was found to have an infiltrate in his right upper lobe on a chest radiograph obtained during evaluation for thoracic scoliosis.
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Amphotericin B nephrotoxicity in humans decreased by salt repletion.
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The masses were soft, painless, and located around her insulin injection sites.
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This report describes the analytical techniques and significance of the zolpidem findings.
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Pulmonary fibrosis is a severe complication associated with bis-chloronitrosourea (BCNU) therapy.
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No concrete predisposing factor was found to be associated with the occurrence of the lesions on the face.
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CONCLUSION: The new quinolone derivatives (levofloxacin, sparfloxacin, grepafloxacin, trovafloxacin, gatifloxacin and moxifloxacin), also called gyrase inhibitors, are known for their potential to cause central nervous system-related adverse effects, including headache, dizziness and insomnia.
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METHOD: A case report.
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Acute graft-versus-host disease of the lung after liver transplantation.
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The lung had become too stiff for the anesthetic circuit bag to be squeezed by hand.
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Aromatic anticonvulsants, sulphamides, minocycline and more rarely carbamazepine are the principal responsible drugs.
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This agent is, however, associated with a rare but serious risk of lactic acidosis.
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Anaphylactic reaction to oral prednisone: a case report and review of the literature.
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Medical evaluations included computerized tomography, lumbar puncture, complete blood counts, serum chemistries, and serologies.
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Neonates who receive prostaglandin E1 at recommended doses for more than 120 hours should be closely monitored for evidence of antral hyperplasia.
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A 26-year-old Japanese man, who had been receiving medical attention for ulcerative colitis for one year, presented with diffuse erythema and pustules on his face and trunk, malaise, and fever up to 39 degrees C one day after the administration of salazosulfapyridine.
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Amphotericin B (AmB) is effective, but its use is limited by toxicity: renal impairment, anaemia, fever, malaise, and hypokalaemia are common.
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This case of linezolid-associated acute interstitial nephritis within the context of a drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a patient treated with linezolid raises concerns about the presumed renal safety of this drug.
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Although visual hallucinations have not been reported as an adverse effect of this agent, we describe three patients who experienced complex visual hallucinations and altered mental status after zonisamide treatment was begun or its dosage increased.
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Multiple complications of propylthiouracil treatment: granulocytopenia, eosinophilia, skin reaction and hepatitis with lymphocyte sensitization.
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A 72-year-old woman with a history of thyrotoxicosis presented with sore throat and fever two weeks after starting carbimazole.
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BACKGROUND: With the pharmacokinetic advantages of intraperitoneal chemotherapy delivery and the increased popularity of immunotherapy and gene therapy, intraperitoneal catheters have moved to the forefront as a delivery system in cancer treatment.
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Immunohistochemistry confirmed some pigment-containing cells to be macrophages.
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We report here the pharmacodynamics and pharmacokinetics of an accidental triamcinolone acetonide (TCA) overdose.
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The conditions may develop months or possibly years after cessation of intake of the drug and further cases may occur, although practolol has been withdrawn from use.
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It was not detected either on FA or ICGA with the conventional camera.
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Atypical ventricular tachycardia (torsade de pointes) induced by amiodarone: arrhythmia previously induced by quinidine and disopyramide.
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OBJECTIVE: To report a case of phenolphthalein-induced toxic epidermal necrolysis (TEN) in a patient maintained on several other medications more commonly known to be associated with TEN.
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The authors suggest that in the absence of any proven benefit of itraconazole prophylaxis, and given the interaction of this drug with vincristine leading to severe and even potentially fatal toxicities, the combination use of these drugs should be avoided.
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Erosion of an intraperitoneal chemotherapy catheter resulting in an enterovaginal fistula.
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On examination, multiple erythematous and brownish hyperkeratotic papules were seen in both axillae.
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The median age was 31 yr (range 2-93).
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A urinalysis was significant for protein 3061 mg/dl, ketones 15 mg/dl, blood 2+, leukocytes 26-50/high-power field, and a protein:creatinine ratio 24.9.
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CASE REPORT: We report a 20-year-old female patient with Crohn's disease who developed WE as a result of thiamine deficiency.
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CONCLUSIONS: The piloerection observed after the replacement of fluvoxamine with milnacipran in this patient appears to have been due to an increase in the alpha(1)-adrenoceptor occupancy by endogenous norepinephrine induced by milnacipran.
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CONCLUSION: beta-blockade treatment was well tolerated and may be beneficial in relieving symptomatic steroid-induced left ventricular outflow tract obstruction in premature infants.
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Progressive outer retinal necrosis is a necrotizing herpetic retinopathy usually seen in immunocompromised patients.
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In both cases, high fever, skin rash, liver dysfunction and atypical lymphocytosis developed 3 weeks after initiating treatment with SASP.
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The patient had been free of interstitial pneumonitis for 14 months, but died of pneumothorax.
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Many women are diagnosed with early stage breast cancer each year who are potential candidates for adjuvant therapy.
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AIM: To report a patient with diabetic rubeosis who suffered from acute retinal ischemic change and stroke after intravitreal injection of bevacizumab.
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Herein, we describe a patient with AIDS who presented to medical attention with pancytopenia 48 months postchemotherapy with etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab (R-EPOCH) for diffuse large B-cell lymphoma.
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The problem of differential diagnosis and treatment.
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Diagnosis of hypothyroidism during treatment can be difficult because of the common side effects of alpha interferon.
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Analysis of the HLA system revealed the positivity of locus DR5, associated with classical KS.
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Lymphoma developing in a patient with rheumatoid arthritis taking methotrexate.
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We report the case of an 87-year-old white woman with myasthenia gravis who presented with nausea, shortness of breath, azotemia, and hyperkalemia shortly after completing a course of intravenous immunoglobulin (IVIG).
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After an uneventful tonsillectomy and extubation, stridor and respiratory distress developed.
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If untreated, or misdiagnosed and treated incorrectly, there may be loss of visual acuity.
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Spinal shock protocol with high-dose methylprednisolone was begun without change.
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We believe that the infection was due to asymptomatic ethmoid sinusitis.
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DISCUSSION: The occurrence of priapism in our patient was related to zuclopenthixol.
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After discontinuation of danazol the diabetes completely resolved.
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Pulmonary eosinophilia or granulomas, classically seen in previously reported cases of methotrexate pneumonitis, were not observed.
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In the other case, a 62-year-old woman, almost all the symptoms subsided after 14 days, and oral dyskinesia persisted for only one additional month.
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In conclusion, patients older than 60 years should have baseline electrolyte measurements before starting therapy with an antidepressant, and these should be monitored not only in the first weeks of treatment, but throughout the full course.
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Recurrent spontaneous intracerebral hemorrhage in a congenitally afibrinogenemic patient: diagnostic pitfalls and therapeutic options.
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Physicians should be cognizant of this potential complication in patients receiving thalidomide or thalidomide-like drugs who present with fever and pulmonary infiltrates and fail to improve despite treatment with broad-spectrum antibiotics.
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During attempted conversion from aripiprazole to clozapine, the patient experienced a significant reduction in psychiatric features.
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Paradoxical enlargement of intracranial tuberculomas during treatment of tuberculous meningitis: report of a case.
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Although this combination agent has been associated with a hypersensitivity syndrome involving cutaneous skin eruptions, pediatric cases of TMP-SMX-induced hepatotoxicity are rare.
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Tracheobronchial obstruction was ruled out by investigation with a fiberoptic bronchoscope.
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Clinicians frequently encounter patients who present with borderline personality disorder (BPD) and prolonged and/or pronounced psychotic symptoms of an atypical nature.
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Detailed pathological study of a case.
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Haptic repositioning was performed in the right eye.
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Central pontine myelinolysis (CPM) is removal of myelin material from neural elements in a way that is not clearly known as yet.
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Early treatment of Niemann-Pick type C patients with cholesterol-lowering agents appeared to have short-term beneficial effects.
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Gynecomastia developed in two epileptic patients some months after the addition of oral fluoresone 750 mg daily to the phenobarbital and phenytoin already being administered.
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Late development of diabetes mellitus after interferon-alfa and ribavirin therapy for chronic hepatitis C: a case report.
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The second is a 29-year-old man with CD in whom nodular sclerosing Hodgkin's lymphoma was diagnosed 3 weeks after infusion with infliximab.
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Systemic chemotherapy induced complete regression of the soft tissue lesion.
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Compared with standard interferon alfa injections, this preparation has a longer half-life allowing for once-weekly injections and superior antiviral efficacy in the treatment of hepatitis C when used in combination with ribavirin.
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