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After 6 months of treatment, systemic lupus erythematosus-related symptoms disappeared and anti-double-stranded DNA returned to normal.
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Postoperatively, he was started on sulindac (Clinoril) 100 mg twice a day.
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Trans-catheter hepatic arterial injection of lipiodol soluble anti-cancer agent SMANCS and ADR suspension in lipiodol combined with arterial embolization and local hyperthermia for treatment of hepatocellular carcinoma.
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Gangrene of the fingertips after bleomycin and methotrexate.
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(1) Acute rehabilitation of a 63-year-old woman with rheumatoid arthritis after replacement of both preexisting knee endoprostheses in one session and removal of the left hip endoprosthesis due to infection and sepsis.
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Aripiprazole in treatment-refractory schizophrenia.
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Early histopathologic changes in purple glove syndrome.
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Thus cabergoline may cause similar pleuropulmonary abnormalities to bromocriptine.
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The renal consequences of indinavir-associated nephrotoxicity are uncertain.
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Inhaled drugs must be used regularly.
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The patient presented with fulminant microangiopathic hemolytic anemia and thrombocytopenia within 48 hr of initiating therapy with trimethoprim-sulfamethoxazole.
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Nasal reconstruction using 20 mg/ml cross-linked hyaluronic acid.
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Phenytoin (Dilantin) is typically employed as prophylactic anticonvulsant in this setting.
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We report a 46-yr-old woman with ovarian carcinoma who developed porphyria cutanea tarda while undergoing treatment with cisplatin and cyclophosphamide.
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Standard care includes the administration of dextrose, glucagon, and diazoxide.
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Chemotherapy-induced Raynaud's phenomenon leading to acral gangrene has rarely been reported.
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At autopsy, blood, brain, and other tissue concentrations of fluoxetine and norfluoxetine were several-fold higher than expected based on literature reports for overdose situations.
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Severe autoimmune hemolytic anemia following rituximab therapy in a patient with a lymphoproliferative disorder.
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Clinicians should be alert to these potential problems in the geriatric population.
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This observation adds another dimension to the previously reported renal complications of nonsteroidal anti-inflammatory agents, especially zomepirac.
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It is known that the intramuscular injection of human chorionic gonadotropin (hCG) lowers the threshold for motor evoked responses (MEPs) in the first dorsal interosseous (FDI) muscle to transcranial magnetic stimulation (TMS) in humans.
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In this report, we describe a rare case of bilateral cryptorchism that did not come to the attention of the physician to implement effective substitution with testosterone until much later in adult life.
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OBJECTIVE: The purpose of this study was to report the concomitant occurrence of multiple squamous cell carcinomas and diffuse nail hyperpigmentation associated with hydroxyurea treatment, and to describe a successful therapeutic approach using imiquimod 5%.
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At the time of admission, he was not receiving any drugs and denied any previous exposure to a hepatotoxic agent.
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Even if the single and total dosage of antiestrogens given to the patient is sufficient to cause tamoxifen retinopathy, this diagnosis can be excluded because, in tamoxifen retinopathy unlike in the case presented here, the deposits are not distributed in all retinal layers.
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Mitral valve prolapse is usually a benign condition, however, serious complications have been reported to be associated with it.
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Arsenic trioxide has recently been introduced as a promising new agent to treat refractory acute promyelocytic leukemia (APL).
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Liver biopsies taken while symptomatic showed portal fibrosis progressing to cirrhosis.
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Other drugs used simultaneously were ruled out by patch and challenge tests.
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He was treated with broad spectrum antibiotics, red cell and single donor platelet transfusions and strict parenteral nutrition.
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During cytotoxic treatment of a child with leukemia we describe the longitudinal course of ionized calcium in a complex syndrome of hypocalcemia and hypoparathyroidism.
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On the 4th day after the infusion, VWF antigen and VWF ristocetin cofactor increased to 40 and 78% of the control, respectively, and dental extractions were performed successfully.
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Endoscopic examination revealed a tumor resembling advanced gastric cancer.
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First case report.
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Despite effective thrombolysis, the plasma fibrinogen level rose during streptokinase administration and reached extremely high values 72 hours later.
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The visual acuity and the RPE atrophy remained stable over the follow-up period of 3 years.
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Gemcitabine therapy has been associated with radiation recall reactions when used in the treatment of carcinoma.
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A 16-year-old white male with acute biphenotypic leukemia developed evidence of the eosinophilia myalgia syndrome associated with total parenteral nutritional support with solutions containing tryptophan, which were given during his initial induction chemotherapy and also after autologous marrow transplantation.
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All symptoms disappeared within 24 h.
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The evaluation, causes, and differential diagnosis of alopecia in a black woman are discussed.
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Aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension in a patient treated with trimethoprim-sulfamethoxazole.
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Then, she again started taking theophylline (75 mg twice daily), and over 2 days reached a steady state serum theophylline level of 12.8 to 14.4 micromol/L (2.3-2.6 microg/mL).
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We report a 43-year-old woman who developed sore throat, swelling of the lips and oral cavity and dysphagia, 2 weeks after the use of budesonide spray (Budefat) for treatment of bronchial asthma.
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Initial vitreous cultures were negative.
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The identification and quantitation procedures of zolpidem in postmortem tissues included dual-column gas chromatography (GC) with nitrogen-phosphorus detection and GC-mass spectrometry.
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We report three cases of abdominal wall metastases from ovarian cancer after laparoscopy.
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Fever caused by the use of furosemide was proved; the fever resolved after discontinuation of this medication and recurred after its reintroduction.
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In two of the patients there appeared to be a correlation between the severity of the psoriasis and the dosage of interferon.
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CASE PRESENTATION: Three cases of Leishmania infantum leishmaniasis in corticosteroid (CS)-treated patients are reported: an isolated lingual leishmaniasis in a farmer treated with CS for asthma, a severe visceral leishmaniasis associated with cutaneous lesions in a woman with myasthenia gravis, and a visceral involvement after cutaneous leishmaniasis in a man receiving CS.
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However, adenosine shortens the antegrade refractoriness of accessory atrioventricular connections and may cause acceleration of the ventricular rate during atrial fibrillation.
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We present a patient who had a superior sagittal sinus thrombosis in addition to his PDPH.
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Report of a case.
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A partial empty sella was found on a computed tomography scan of the hypothalamic-pituitary region.
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Beginning ductopenia was present in two, suggesting that itraconazole might be responsible for the occurrence of prolonged drug-induced cholangiopathy.
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Clonazepam, thioridazine, beta-blockers, anticholinergics, and bromocriptine did not ameliorate his akathisia.
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These results indicate that lithium may cause biochemical hyperparathyroidism.
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Treatment was completed without further complication by using amphotericin B and ketoconazole concurrently.
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The association between the use of cyproterone acetate and liver abnormalities is poorly documented.
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PATIENT: An 8-yr-old with acquired immunodeficiency syndrome with a large organized intraatrial thrombus at the tip of an indwelling central venous catheter placed for total parenteral nutrition 2 months before presentation.
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He had priapism following the use of olanzapine.
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Three infants with supraventricular tachycardia and congestive cardiac failure were given verapamil intravenously.
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Radiation recall related to gemcitabine has been reported in lung and breast cancer.
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The authors report a case of focal myocardial necrosis, presenting clinically as an acute myocardial infarction during the administration of the antineoplastic drug, amsacrine, in a patient without coronary artery disease.
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By contrast, PDCs were present at very low levels in atopic dermatitis and not detected in normal human skin.
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We report a case of bacterial keratitis that occurred after laser-assisted subepithelial keratectomy.
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The adverse hematologic effects are usually transitory and pancytopenia is not frequent.
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She experienced intense pain in the first postoperative week and obtained topical oxybuprocaine for pain relief.
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Aluminum intoxication developed in three infants with azotemia who were not undergoing dialysis and who had been treated with aluminum hydroxide from the first month of life.
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Development and course of subjective and objective phenomena seem to be typical for patients in whom Ukrain could induce long-term complete remission.
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Thrombotic microangiopathy (TMA) is a serious toxicity associated with a small number of antineoplastic agents.
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Most importantly, it occurs only after high doses of mannitol (> 200 g/day or cumulative dose of > 400 g in 48 hours), but not at lower doses.
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Induction of systemic lupus erythematosus by interferon-gamma in a patient with rheumatoid arthritis.
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Meningitis can be caused in experimental performing a lumbar puncture (LP) after bacteraemia.
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RESULTS: Of the 74 neonates evaluated, 65 had no signs of gastric obstruction and were considered normal; 5 had clinical and radiologic or pathological evidence of gastric obstruction consistent with the presence of antral mucosal hyperplasia.
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Two cases of sirolimus-associated pneumonitis have been reported after cardiac transplantation.
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We present herein the case of a 56-year-old woman in whom bilateral and recurrent SSP was caused by the rupture of pulmonary lacunae induced by chemotherapy, given for bilateral lung metastases secondary to breast carcinoma.
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Its safety, even in these extreme conditions, is particularly reassuring.
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However, the similarities between patient reports and reports from healthcare professionals in most frequently reported ADRs and most frequently reported drugs are striking.
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We report the case of a patient who developed polyserositis (pericardial effusion, pleural effusion, and pericarditis) after being started on clozapine, and whose symptoms remitted upon discontinuation of clozapine.
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A patient with coccidioidal meningitis was treated with intrathecally administered amphotericin B, and an acute toxic delirium with EEG abnormalities developed.
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We report a 43-year-old woman who developed sore throat, swelling of the lips and oral cavity and dysphagia, 2 weeks after the use of budesonide spray (Budefat) for treatment of bronchial asthma.
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As bilateral subthalamic nucleus (STN) stimulation produced improvement in his motor symptoms, his drug dosages were reduced postoperatively.
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An investigation of malaria in a US patient without recent travel established Plasmodium falciparum molecular genotype identity in 2 patients who shared a hospital room.
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The exophthalmos improved dramatically within 72 hours of the withdrawal of lithium.
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By contrast, the appearance of a hypercalcemia has yet to be described.
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She had been treated by Carbamazepine 1000 mg/day for neuropathic pain for 2 years without clinical or laboratory signs of toxicity.
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Anaphylactic reaction to recombinant insulin-like growth factor-I.
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Although a causative association between trastuzumab and this patient's pulmonary syndrome was not proven, the potential for this toxicity should be considered.
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Patients with large pelvic tumor loads are, according to existing classifications, at high risk to die and to develop drug resistance.
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Eleven patients developed infection requiring hospitalization while taking leflunomide including: lower respiratory tract infections (3), cellulitis (2), disseminated herpes zoster (2), probable TB liver (1), abdominal sepsis (1), mycotic aneurysm (1) and gastroenteritis (1).
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Bone marrow biopsy revealed no evidence of neoplasia.
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These medications do not require medical prescriptions, so often parents use them, bypassing paediatricians.
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Physicians should be aware of the risk of severe AIHA in CLL patients with a history of AIHA or positivation of the DAT during previous fludarabine administration, or in case of secondary fixation of complement to the red cell membrane occurring during fludarabine treatment.
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Growth hormone and respiratory compromise in Prader-Willi Syndrome.
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In both instances, reversion of intraventricular conduction to normal occurred within 72 hours, coinciding with clearance of carbamazepine from the blood stream.
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A liver biopsy shortly after abstinence showed extensive pericellular fibrosis, but a biopsy after 6 years showed very mild fibrosis.
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Resin hemoperfusion for chloramphenicol intoxication.
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All patients underwent classic therapy.
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However, the toxicity profile of leflunomide in patients with underlying GVHD remains to be defined.
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OBJECTIVE: To describe a case of cefazolin-induced leukopenia in a critically ill patient who developed this adverse reaction upon rechallenge with cefoxitin.
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