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Unlike other macrolide antibiotics, it is not hepatically metabolized and did not produce an interaction with warfarin in a single-dose study.
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Two patients with ovarian cancer who had received multiple courses of cisplatin without complications experienced hypersensitivity reactions to cisplatin: one, involving intrahepatic artery infusion, manifested general erythema, dyspnea, and hypotension; the other, involving intravenous infusion, manifested abdominal pain, general erythema, and fever.
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Histiocytic lymphoma of the ileocecal region after chemotherapy for multiple myeloma.
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We report on a patient with acromegaly who developed severe drug-induced hepatitis during combined treatment with the long-acting somatostatin-analog octreotide and the GH receptor antagonist pegvisomant.
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CASE REPORT: This 36-year-old woman had rheumatoid arthritis that proved refractory to sulfasalazine and methotrexate, which were used successively in combination with symptomatic drugs.
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Primary central nervous system lymphoma in a patient treated with natalizumab.
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A patient with a second-degree burn of the forehead, induced by topical application of crushed garlic is reported.
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The HIV protease inhibitor indinavir may cause nephrolithiasis and interstitial nephritis.
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This side effect has never been reported for this nitrosourea but only for BCNU and methyl-CCNU.
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TD was relatively mild, with a mean score of 4.75, and tended to accentuate with an activation procedure of rapid pronation and supination of the hands.
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The development of cutaneous ecchymosis associated with a sudden fall in hemoglobin after the administration of alteplase should strongly suggest the possibility of diffuse subfascial hematoma.
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Systemic allergic contact dermatitis to 8-methoxypsoralen (8-MOP).
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Current therapy with oral baclofen and benzodiazepines is useful but has variable success, particularly in severe cases.
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In case of relapse the clinically important question of discontinuation of lithium versus the concurrent use of ECT and lithium may arise.
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We wish to alert other anaesthetists that the use of epidural anaesthesia in this setting may mask the symptoms and delay the diagnosis of this rare complication.
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We report four cases of encephalopathy coincident with elevated aluminum levels as well as one patient who developed seizures while receiving continuous bladder irrigations with alum.
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We describe a case of extensive thromboembolism associated with antithrombin (AT) deficiency complicated by thrombocytopenia which resolved when low-molecular-weight heparin was instituted.
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Protease inhibitors (ritonavir and saquinavir) were added to the treatment and the patient developed progressive ataxia related to carbamazepine toxicity.
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Diffuse proliferative glomerulonephritis after bone marrow transplantation.
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Although both the spontaneous occurrence of SLE and the psychosis as a sign of CNS involvement of SLE cannot be excluded, SLE could be considered as an adverse effect of carbamazepine.
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We described the occurrence of L-dopa-induced myoclonus and seizures in a case of parkinsonism with its SEPs findings.
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Glycopeptide-induced neutropenia: cross-reactivity between vancomycin and teicoplanin.
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Bronchiolitis obliterans organizing pneumonia simulating progression in bronchioloalveolar carcinoma.
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A 68-year-old male was admitted for interstitial pneumonia associated with scleroderma.
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Treatment of neutropenia in a renal transplant recipient with granulocyte colony-stimulating factor.
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Ibuprofen rarely causes lower gastrointestinal adverse reactions but has been implicated in systemic and local side effects in patients with lupus.
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OBJECTIVE: 1) To describe a patient with rheumatoid arthritis receiving adalimumab who developed fever, pancytopenia, splenomegaly, and extreme hyperferritinemia.
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Several years after the original diagnosis, he was found to be ACTH deficient and following commencement of hydrocortisone replacement therapy became hypernatraemic.
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Drug-induced hepatitis in an acromegalic patient during combined treatment with pegvisomant and octreotide long-acting repeatable attributed to the use of pegvisomant.
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Within hours of leaving the operating room, he began to develop postoperative neurologic deficits in his extremities, which progressed to a classic Brown-Sequard syndrome.
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Cluster-like headache after surgical crystalline removal and intraocular lens implant: a case report.
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Drug-induced rhabdomyolysis is an established but rare adverse effect of high doses of cholesterol-lowering agents (statins) or interactions between drugs (eg, statins and fibrates).
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Methemoglobinemia after axillary block with bupivacaine and additional injection of lidocaine in the operative field.
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Hereditary motor and sensory neuropathy type 1 (HMSN-1) is an autosomal dominant disorder, which is usually not associated with neoplastic diseases.
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The patient described feeling cold with worsening headache and chills approximately one hour after infusion of the first dose of penicillin.
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We also interviewed a series of 14 women in California who had recent Accutane-exposed pregnancies to identify opportunities for prevention.
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Physicians who use sulfasalazine to treat patients with inflammatory bowel disease should be aware of the signs of sulfasalazine-induced lupus syndrome.
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A case is presented where combined intravitreal triamcinolone and photodynamic therapy stopped the progression of the exudative macular degeneration.
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The both agents were given for 3 weeks and were well tolerated without any side effects.
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The only adverse effect was atrioventricular block in two children, which was completely reversible.
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After 3 weeks of CI a thrombus formation in the portal vein was detected by ultrasound and confirmed by duplex ultrasound.
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Tolerance to dobutamine was obviated by giving infusions twice weekly.
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These perfusions gave a moderate or good temporary palliation as regards to tumor growths on the extremity.
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Aircrews are tested every 3 mo for HbA1c levels.
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DESIGN AND METHODS: A specimen of resected TSHoma tissue from our case was immunohistochemically examined for expression of somatostatin receptor 2A (SSTR2A) and PPAR gamma.
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We experienced 2 cases of mequitazine-induced photosensitivity reaction in patients who took mequitazine for their dermatologic problems.
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He presented symptoms of fever, skin lesions consisting of multiple vesiculopapular rashes, pruritic maculae and bullae, and mucosal involvement of the eyes, lips, oral cavity, and anorectal junction.
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The mother had used lamotrigine in increasing doses throughout pregnancy, and at the time of the apneic episodes, she used 850 mg/day.
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CONCLUSIONS: Clinicians treating elderly patients with olanzapine should be aware of the potential for rapidly developing hyperglycemia and monitor such patients accordingly.
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Cutaneous seeding after ultrasound-guided percutaneous ethanol injection for treatment of hepatocellular carcinoma.
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We present a case of acute epinephrine toxicity resulting in acute myocardial ischemia in a young boy with combined variable immunodeficiency syndrome who developed severe allergic reaction to intravenous immunoglobulin, and was subsequently given epinephrine by mistake intravenously rather than subcutaneously.
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The drug was prescribed for transient ischemic cerebrovascular accidents.
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We report a patient with a malignancy and upper gastrointestinal bleeding who underwent a gastric lavage followed by an endoscopy as part of her investigations.
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Nineteen cases of unusual enhanced vincristine neurotoxicity related to itraconazole have been reported in children.
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The chemotherapy regimen consisted of cis-platinum, etoposide, actinomycin-D, and intrathecal methotrexate (PEA-M).
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We propose a prophylactic and curative approach to decrease morbidity related to CMV infection in active UC.
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In addition, not enough controlled clinical trials have yet been conducted.
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The use of therapeutic drugs forms one of the important causes of hiccups.
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Paranoid psychosis may result from intoxication with, or withdrawal from amphetamines.
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8 months later she was scheduled for salvage chemotherapy with gemcitabine (1,000 mg/m(2) days 1 and 8) and docetaxel (75 mg/m(2) day 8) due to locally progressive disease.
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RESULTS: The suggested algorithm includes: 1) Supportive care and withdrawal of all potentially offending agents; 2) Laboratory evaluation with prompt initiation of treatment for both disorders--cyproheptadine for SS and dantrolene for NMS; 3) Do not use bromocriptine (contraindicated in SS) or chlorpromazine (contraindicated in NMS) initially; 4) Add bromocriptine when clinical presentation becomes consistent with NMS (SS can be prolonged if serotonergic agent has long half-life).
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We suggest that familiar TGA could be caused by the mechanism of vasospasm rather than venous congestion and that the abnormal cerebral vasomotor control could be the hereditary substrate in this condition.
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Steroid diabetes experienced by the reported cases may be a marker for the onset of diabetes in their adulthood.
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The process worsened during the two weeks following steroid cessation.
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Speech arrest, agitation, tremor, ataxia, and downward gaze deviation in a 5-year-old female 13 days after orthotopic liver transplant are reported.
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Still, our data suggest that ethnic background is an important predictor of finding 1 of the presently known mutations, and the knowledge of ancestries atypical for FMF can suggest the diagnosis of other hereditary periodic fever syndromes.
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During repeat transesophageal atrial pacing for recurrent SVT, ventricular fibrillation occurred.
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We have confirmed in 5 patients that continuous administration of folinic acid with weekly oral methotrexate prevents improvement of psoriasis.
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Prompt correction of hyponatremia by administration of hypertonic saline solution was followed by resolution of all neurologic defects.
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Choanal atresia and athelia: methimazole teratogenicity or a new syndrome?
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We suggest that meloxicam might have intestinal toxic effects when taken in high doses, because of reduced COX-2 selectivity.
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Quinine and its isomer quinidine are well-known causes of iatrogenic hypoglycaemia, due to excessive insulin secretion.
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Stevens-Johnson syndrome (SJS) is a serious and potentially life-threatening disease.
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Hospital records were reviewed when available.
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DESIGN: Descriptive case series.
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We describe a patient with acute disseminated encephalomyelitis (ADEM) who was treated with high-dose intravenous methylprednisolone 2 days after onset of neurologic symptoms.
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Isoniazid inhibits the metabolism of phenytoin.
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OBJECTIVE: To report a case of fatal hyperkalemia owing to succinylcholine administration in a patient with mucositis secondary to chemotherapy.
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This 41-year-old woman had been on tamoxifen therapy for 3 years due to breast cancer.
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Bisabolol is a sesquiterpene alcohol compound derived from the German chamomile plant, a member of the Compositae family.
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The only two studies addressing this issue showed no problems with diagnosis caused by providing narcotic pain relief.
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We now present four cases of RSDS in kidney transplant recipients treated with tacrolimus.
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Intentional overdose with tiagabine: an unusual clinical presentation.
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We report a case of an 11-year-old boy who experienced an anaphylactic reaction after administration of bacitracin ointment.
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Radiotherapy has been the predominant treatment in the past, but more recently multi-modality treatments have been utilised.
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More than 15,000 cases have been treated by chemonucleolysis world-wide.
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This syndrome is not well known but is associated with a high mortality rate.
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Rapid warfarin reversal with factor VIIa in an elderly trauma patient with retroperitoneal hematoma.
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Foscarnet-induced severe hypomagnesemia and other electrolyte disorders.
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Power spectrum analysis of heart rate variability demonstrated marked abnormalities in autonomic nervous system activity.
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Lichen planus and acne provoked by gold.
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Although this is an intriguing hypothesis, any causative role of etanercept remains unproven at this stage.
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It binds to both active and inactive conformations of the ABL gene and is 325 times more potent than imatinib in inhibiting the growth of BCR/ABL cells in vitro (Morelock and Sahn, Chest 1999;116:212-21; Huggins and Sahn, Clin Chest Med 2004;25:141-53).
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To treat hepatitis B, interferon alpha was administered until the proximal muscle weakness developed.
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This case suggests that coronary arterial involvement in systemic lupus erythematosus may be related to coronary arterial spasm.
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A patient is described with the characteristic features of phenytoin hypersensitivity syndrome (PHS) including fever, erythroderma, tibial and facial oedema, pinhead-sized facial pustules and abnormal liver function tests.
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Intravitreal triamcinolone may have had an influence on the exacerbation of retinochoroiditis in the posterior pole of the patient.
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The infant died despite intensive resuscitative efforts, including the use of digoxin-specific Fab antibodies.
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Cranial MRI showed large asymmetric T2 and FLAIR hyperintense lesions in cortical and subcortical structures.
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METHOD: Case analysis of a poly-drug overdose (venlafaxine, topiramate, divalproex sodium, risperidone, and carbamazepine) presenting with mixed SS/NMS features and whose clinical management suggests a practical algorithm for treatment of undifferentiated SS/NMS in critical care settings.
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