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Recommended treatment duration is 6 to 12 months with frequent imaging.
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Toxic hepatitis due to combination therapy with methotrexate and etretinate in psoriasis.
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We discuss a patient who developed severe renal tubular dysfunction secondary to short-term therapy with Amikacin, resulting in refractory hypokalemia, hypocalcemia, hypomagnesemia, metabolic alkalosis, and polyuria.
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Both the clinical picture of the patient as well as laboratory, imaging and histopathological findings may help in the diagnosis.
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All of these have been able to reduce oral prednisone doses.
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Both infiltrates initially improved on topical antibiotic therapy, but over the next 18 days, 1 infiltrate worsened and repeat cultures were performed, which demonstrated A fumigatus.
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We report the case of a 14-year-old female with acute promyelocytic leukemia who developed symptomatic cardiomyopathy only 4 months into treatment with a combination of daunomycin and all-trans retinoic acid (ATRA).
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One victim was hospitalized.
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Myasthenia gravis is an autoimmune disorder where antibodies against the nicotinic Ach receptor resulting in impaired transmission at the NM junction.
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Hydrocortisone may decrease the incidence of mortality associated with cardiac arrhythmias in children receiving amphotericin B overdoses.
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It may also appear in complete remission after chemotherapy (chemotherapy-related).
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We report three cases of ehrlichiosis in pediatric oncology patients, one of whom was a stem cell transplant recipient.
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Bone marrow needle aspirate showed a normal trilineage differentiation.
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Although fluoxetine-induced headache occurred in one patient, the other five reported no side effects at the doses used.
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The probability of developing acute leukemia in this study was not significantly correlated to the total cumulative dosage of Treosulfan.
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All of them had the obstructive type of HCM (HOCM).
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Electromyogram and nerve conduction studies showed sensorimotor peripheral neuropathy in both patients.
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Appropriate treatment for neurosyphilis was instituted.
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The patient's clinical presentation, histologic features on liver biopsy and favorable course after stopping the drug suggest that barbiturates can be added to the list of agents which can cause submassive hepatic necrosis.
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Complete resolution of the diarrhea occurred shortly thereafter.
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Mesenteric desmoid tumors are a recognized sequela of colectomy for polyposis coli of Gardner's type.
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Acute enlargement and subsequent rupture of an abdominal aortic aneurysm in a patient receiving chemotherapy for pancreatic carcinoma.
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Granulocytic sarcoma: local presentation of a systemic disease.
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METHODS AND RESULTS: A case of high grade superficial bladder caner treated with intravesical BCG which has successfully cleared her bladder cancer nevertheless has lead to bladder contracture for which case she may need bladder reconstruction/augmentation surgery if she remained disease free added to her psychological and social effects on her life.
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Fibrosis of corpus cavernosum after intracavernous injection of phentolamine/papaverine.
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The patient had been receiving bisphosphonate therapy prior to admission and this may have contributed to the severity of the problem.
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In addition to its known effect on gallbladder stasis, octreotide alters bile acid composition and may thus hasten intrahepatic sludge and stone formation.
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The potential risk of carcinogenicity has delayed more extensive clinical trials.
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Efforts to reduce the glucose levels and long-term complications increase the frequency of hypoglycemia.
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There was no evidence of disease progression.
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Twenty-seven consecutive patients admitted for an acute CAD were investigated using a standardized imaging protocol.
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No guidelines exist for calculating doses by either actual or ideal weight, and the calculated doses may vary by as much as 25%.
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We present two cases of neonates with gastric mucosa and submucosa hyperplasia revealed during ultrasound examination.
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Routine ophthalmic observation for the development of optic neuropathy is strongly recommended for patients with significant risk factors that could increase the chance of side effects and those on longer treatment courses.
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The TC usually develop in the presence of secondary hyperparathyroidism or a high calcium x phosphate product, while other factors have been also occasionally implicated in their development.
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Treatment with amiodarone was continued; however, therapy with L-thyroxin was initiated, followed by a complete regression of the goiter.
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Aggressive use of H2-antagonists to prevent gastrointestinal bleeding in septic patients will reduce the need for orally administered antacids.
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A week before the onset of hepatitis, the patient complained of upper gastrointestinal symptoms and was treated for gastritis.
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Neuroleptic malignant syndrome during abrupt reduction of neuroleptic treatment.
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It appears that this secondary malignancy was due to his prolonged chemotherapy.
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PURPOSE: To report that acute lamotrigine poisoning may result in severe encephalopathy.
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After 1 month of follow-up the patient underwent TEE which showed a dramatic reduction of the left atrial thrombosis.
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After first and second line chemotherapy we started third line chemotherapy consisting of calcium folinate (1,000 mg) and 5-FU (4,000 mg) mixed together in a total volume of 240 ml in an ambulatory pump and administered over a period of 24 h.
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We hypothesize that chronic inflammation of the pleura, caused by decades of empyema, associated with the presence of heterotopic squamous epithelium due to a long-standing esophago-pleural fistula, led to neoplastic transformation.
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Forty-five days after therapy, the patient returned with a severe necrotizing uveitis in the posterior pole and vitritis.
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An intertriginous eruption with histological features of epidermal dysmaturation and an interface dermatitis has been previously reported in the dermatopathology literature.
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Eleven patients developed infection requiring hospitalization while taking leflunomide including: lower respiratory tract infections (3), cellulitis (2), disseminated herpes zoster (2), probable TB liver (1), abdominal sepsis (1), mycotic aneurysm (1) and gastroenteritis (1).
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She had received this same dose in the past without incident.
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Amlodipine was given for the treatment of hypertension.
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The former had a slowly progressive course, did not respond to amphotericin B (AB), and died; the latter improved after a prolonged course of liposomal-AB.
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The expanded allele segregated with neurological signs in one kindred.
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CONCLUSIONS: This study shows that psoriasis can be driven by the innate immune system through TLR ligation.
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A 65-year-old woman with angina pectoris presented with syncope after sublingual ingestion of isosorbide dinitrate (5 mg).
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That time the only effective treatment was ventricular pacing.
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For the treatment of the latter, early peritoneal dialysis is recommended for in utero exposure to captopril and enalapril, although the outcome is poor.
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The patient had a favorable outcome.
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Persistent CSF leak may also be present without PDPH.
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Following therapy with AmBisome his symptoms abated and significantly improved scan picture was seen.
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Our case illustrates the importance of continuing adequate opiate therapy perioperatively in the increasing number of opioid-dependent patients to prevent potentially life-threatening complications such as broken heart syndrome.
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The usual treatment includes quick relief bronchodilator medications of the sympathomimetic class and controller medications that may include the long-acting inhaled bronchodilator salmeterol.
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In recent years there has been an increase in the use of ACE inhibitors in the paediatric population.
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The present case suggests that acute exacerbation of hepatitis can occur with steroid-free regimen.
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To date, eight cases of TEN and one of SJS related to lamotrigine administration have been reported in the literature.
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Neuropsychologic evaluation revealed global cognitive deficits; he was found to be a carrier of a PS-1 point mutation at position G206A.
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The patient survived pulmonary leukostasis, resumed therapy, and achieved a CR.
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The patient's hematocrit eventually stabilized and was 30% at discharge.
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Individual risk/benefit assessment is important, and close monitoring of both mother and child is advisable, especially during the first 3 weeks postpartum.
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There are insufficient data about the use of immunosuppressive agents in the treatment of FMF attacks; however, we now successfully control the attacks with colchicine 0.5 mg/d and azathioprine 2 mg/kg/d.
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Plasma concentrations were also measured before and after ten dialysis sessions during four courses of ifosfamide therapy.
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First, a review of the literature produced 41 anecdotic cases of neutropenia or agranulocytosis during treatment with olanzapine (Zyprexa) reported in a total of 24 publications.
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However, the impact of cytomegalovirus on PTLD remains to be determined.
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Microscopic examination of a skin scraping revealed a heavy infestation of cheyletiella yasguri, as identified by the presence of hoks of the palpi and the heart-shaped sensory organ on genu I.
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Acute generalized exanthematous pustulosis induced by salazosulfapyridine in a patient with ulcerative colitis.
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A 57-year-old woman was scheduled to receive recombinant interferon-alpha retreatment for chronic active hepatitis C.
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We report 4 patients, 2 on methylphenidate and 2 on dextroamphetamine who presented with acral cyanosis, livedo reticularis, or Raynaud phenomenon.
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We report a case of severe hypotension associated with intravenous valproate used to treat status epilepticus in an 11-year-old girl.
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CONCLUSION: The final interpretation of the lesions was multiple focal radiation necrosis based on perfusion abnormalities after chemotherapy and conformal hyperfractionated radiotherapy, probably due to an individually enhanced vulnerability of the cerebral vessels.
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This case suggests that sarcoidosis and pravastatin, two entities not frequently associated with myotonia, may interact in a synergistic manner to produce severe clinical myotonia in humans.
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However, little has been reported about conditions surrounding the change in QT interval after the steady state is achieved that may have implications in the safety and efficacy of the drug.
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Subsequently, the patient again became severely leukopenic (WBC count 2.4 x 10(3)/microL).
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Amebic keratitis was diagnosed following corneal biopsy and cultures which grew Acanthamoeba of a species similar to, but not identical with, Acanthamoeba polyphaga.
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Recurrent fractures in an elderly patient with systemic lupus erythematosus.
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The diagnosis, pathogenesis and issues relevant to the treatment of this condition are discussed.
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Drugs metabolized by the same enzyme may interact with each other.
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Neuroleptic malignant syndrome in a patient with succinic semialdehyde dehydrogenase deficiency.
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Two months later, a second arrhythmia cluster occurred that was controlled by the addition of amiodarone.
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While acute toxicity is not infrequently reported, a recent experience in an adult who received five consecutive daily doses of VCR (1.0 mg/m2) in conjunction with two other drugs led to a sequence of life-threatening toxicities which were not obviously ameliorated by folinic acid rescue as has been recently advocated.
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PURPOSE: A case of probable enoxaparin-induced hepatotoxicity is described.
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OBJECTIVE: This article discusses the management of an insulin dependent diabetic man aged 52 years presenting with 17 torso basal cell carcinomas (BCCs); mostly superficial BCCs (SBCCs).
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After therapy with parenteral amiodarone (2300 mg in 3 days) and other measures, signs of congestive heart failure disappeared; subsequently the patient developed jaundice, marked increase in serum transaminase levels and fall in prothrombin time, and histologic changes of severe centrilobular necrosis were observed in hepatic biopsy.
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The patient died in 1995 March at the age of 29 years of sudden septic shock related to Pseudomonas aeruginosa infection.
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PURPOSE: The differentiating characteristics in blebitis and early and late endophthalmitis after glaucoma filtration surgery are reviewed.
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Sildenafil should be considered in the treatment of PLE after the Fontan procedure.
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Gastrointestinal hemorrhage due to duodenal erosion by a biliary wallstent.
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Although radiation-induced laryngeal necrosis has become a rare complication, the combination of chemotherapy and radiation therapy may increase its incidence.
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This association should be considered in the period after vasopressin-treated gastrointestinal hemorrhage.
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It cannot be assumed that the development of a mediastinal mass or its persistence following chemotherapy is due to recurrent or residual disease.
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These are the first reported patients to show mfERG abnormalities that correspond to bitemporal visual field defects and add to the growing evidence that ethambutol damages the retina.
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Both reactions were categorized as probable according to the Naranjo probability scale.
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Neurotoxicity is a common complication during cancer chemotherapy.
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