text
stringlengths
7
742
label
int64
0
1
label_text
stringclasses
2 values
The onset and duration of symptoms correlated directly to drug ingestion.
0
Not-Related
This report describes a 13-year-old female with a right frontal high-grade glioma and complex partial seizures who developed localized purpura after 23 months of lamotrigine monotherapy.
1
Related
While undergoing treatment with albendazole, he developed worsening diarrhea with abdominal pain and fever.
1
Related
Five of the patients received no radiotherapy.
0
Not-Related
After discontinuation she developed adrenal insufficiency, for which she needed substitution of steroids.
0
Not-Related
The authors describe a case of neuroleptic malignant syndrome that occurred in a patient on amitriptyline and lithium carbonate.
1
Related
The CYP2D6 phenotype, determined when the patient received the antidepressant comedication, characterized a poor metabolizer status (dextromethorphan metabolic ratio >0.3), despite a heterozygous genotype containing a wild-type allele with extensive metabolic capacity and a mutant non-functional allele (CYP2D6*1A/CYP2D6*4A).
0
Not-Related
A kidney transplantation recipient 1983 to 1995, she was diagnosed with Charcot-Marie Tooth disease in 1991.
0
Not-Related
IMPLICATIONS: Dexmedetomidine, an alpha(2)-adrenoceptor agonist, is indicated for sedating patients on mechanical ventilation.
0
Not-Related
Urethral syndrome patients have irritative bladder symptoms in the absence of any objective urological findings.
0
Not-Related
RESULTS: Our patient developed Crohn's disease while on Copaxone treatment as a consequence of long-term immunosuppression.
1
Related
A review of the literature indicates that even when given at much higher doses than are needed for treating heroin or alcohol abusers, there is no evidence that NTX causes clinically significant liver disease or exacerbates, even at high doses, serious pre-existing liver disease.
0
Not-Related
This paper reports on a 6.9-year-old autistic male who developed repeated episodes of acute dystonic reactions associated with pimozide administration at the doses of 0.096 mg/kg/day and 0.032 mg/kg/day and 32 hours following pimozide withdrawal, as well as during subsequent thioridazine administration.
1
Related
Four patients with severe lactic acidosis associated with septic shock were treated with sodium dichloroacetate (DCA) (50 mg/kg body wt), an activator of pyruvate dehydrogenase.
0
Not-Related
It is suggested that an allergic background may play an important role in the development of EP in patients on CAPD.
0
Not-Related
The high rate of retinopathy in patients with hypertension suggests that patients should be carefully monitored.
0
Not-Related
We describe the clinical, radiological and pathologic findings of a case of epithelioid angiosarcoma of the lung presenting with persistent haemoptysis who had undergone remote lung collapse therapy with Lucite plombage.
0
Not-Related
Clinicians should be aware of this risk and ask about it during routine clinic follow-up for spasticity.
0
Not-Related
Following three courses of chemotherapy with cyclophosphamide, methotrexate, and 5-fluorouracil (CMF), the patient had a dramatic clinical reduction of tumor, reduction of serum CA 15-3 from 161 to 64 U/ml, and underwent a modified radical mastectomy and axillary dissection.
0
Not-Related
A 73-year-old man was admitted for treatment of pleural dissemination that was a recurrence after right lower bilectomy for advanced lung cancer.
0
Not-Related
Although interferon gamma has been implicated in the pathogenesis of sarcoidosis, only a few cases of sarcoidosis associated with interferon alpha therapy have been reported.
1
Related
Concomitant irradiation apparently enhanced the skin toxicity of aminoglutethimide or possibly aminoglutethimide had a radiosensitizing role in this patient.
1
Related
Ectopic adrenocorticotrophic (ACTH) syndrome and small cell carcinoma of the lung-assessment of clinical implications in patients on combination chemotherapy.
0
Not-Related
Major points illustrated are, (1) occurrence of HIT with any dose or form of heparin; (2) misperceptions on the diagnostic criteria; (3) correct (thrombin inhibitors) and incorrect (platelet transfusions and warfarin) management; (4) influence of management strategy on clinical outcomes; (5) severity of the syndrome; and (6) potential for both anamnestic response to heparin and disappearance of HIT antibodies over time.
1
Related
A patient who had been treated with large doses of thyroid hormone for several years developed features of secondary hypothyroidism after thyroid hormone withdrawal.
1
Related
Faultless aseptic technique is essential when administering hyaluronate viscosupplementation.
0
Not-Related
In vitro lymphocyte transformation studies confirmed cross-reactivity to one or more aromatic AEDs in 3 patients.
0
Not-Related
When platinum-containing agents are administered, patients should be closely monitored for hypersensitivity reactions, even in previously uncomplicated cases.
0
Not-Related
CONCLUSIONS: This report indicates clindamycin phosphate vaginal cream as the most probable cause of CDIC due to the temporal relationship between the occurrence of diarrhea and clindamycin administration, lack of concomitant medications, and documentation of C. difficile toxin.
1
Related
Symptoms are usually considered nonspecific, and gastroscopy with biopsy is usually performed to establish the diagnosis.
0
Not-Related
Captopril-induced acute reversible renal failure.
1
Related
Both these cases of PTLD achieved a complete response following treatment with IVIG, gancyclovir, solumedrol and interferon (IFN).
0
Not-Related
CONCLUSIONS: The value of multihormonal therapy in breast carcinoma is not established, and the addition of progestogens to tamoxifen may not reduce of developing endometrial lesions, including carcinoma.
1
Related
Intrathecal methotrexate-induced acute cerebellar syndrome.
1
Related
Neonatal mydriasis: intravenous lidocaine adverse reaction.
1
Related
Phenolphthalein-induced toxic epidermal necrolysis.
1
Related
MRI with gadolinium enhancement demonstrated prominent multifocal enhancing white matter lesions.
0
Not-Related
Mycophenolate mofetil may be considered as a useful alternative in the treatment of severe myasthenia gravis when standard therapeutic regimens fail.
0
Not-Related
The results of the ultrasound examination combined with clinical anamnesis allowed diagnosis of gastric mucosa foveolar hyperplasia due to prolonged PGE1 therapy.
1
Related
During the course of chemotherapy, HBsAg gradually became positive, but no liver dysfunction was apparent until after completion of the chemotherapy.
0
Not-Related
After two months of hospitalization, a pruritic dermatitis near the left scapula developed.
0
Not-Related
A Chinese female with 10 years' history of a special form of tardive dystonia (Pisa syndrome) is described.
0
Not-Related
It has minimal side effects in transplant recipients and appears to be an effective initial treatment for this severe infection.
0
Not-Related
Sclerodermatous syndrome after occupational exposure to herbicides--response to systemic steroids.
0
Not-Related
We describe the development of ischemic colitis in a woman who was treated with tegaserod and review the relationship among ischemic colitis, tegaserod use, and irritable bowel syndrome.
1
Related
Severely elevated serum lithium levels were found.
0
Not-Related
We describe a renal transplant recipient maintained on cyclosporine and prednisone developing Nocardia Asteroides brain abscess.
1
Related
Drug rash with eosinophilia and systemic symptoms (DRESS), also known as drug-induced hypersensitivity syndrome (DIHS), is a severe adverse drug reaction affecting multiple organs caused by drug treatment.
0
Not-Related
CONCLUSION: We report a case of the use of pamidronate for significant hypercalcemia secondary to acute vitamin D poisoning.
1
Related
Marked QT prolongation and torsades de pointes secondary to acute ischemia in an elderly man taking dofetilide for atrial fibrillation: a cautionary tale.
1
Related
The most remarkable feature was the presence of diamond-shaped Russell bodies in 20% of the plasma cells of the second biopsy specimen.
0
Not-Related
Occasionally missed doses may lead to pervasive non-adherence with relapse a likely outcome.
0
Not-Related
In each case, control was achieved rapidly after initiation and titration of a continuous haloperidol infusion.
0
Not-Related
Treatment was discontinued; the patient was managed with monitored IV hydration and loop diuretics, high dose corticosteroids and fresh frozen plasma infusions and recovered completely.
0
Not-Related
Hairy cell leukemia, a low-grade B-cell lymphoproliferation, has not been recognized as part of the PTLD spectrum.
0
Not-Related
We reviewed the literature for similar cases of aortoiliac thrombosis in newborns; some were managed by medical means, others by operation.
0
Not-Related
Drug-drug interaction between itraconazole and efavirenz in a patient with AIDS and disseminated histoplasmosis.
0
Not-Related
Six (25%) of 24 patients died of this infection; however, only one (5%) of 19 who were treated with adequate antimicrobial therapy died.
0
Not-Related
The literature concerning formalin therapy is reviewed.
0
Not-Related
Eyelid necrosis following intralesional corticosteroid injection for capillary hemangioma.
0
Not-Related
RESULTS: In one patient the rifampin-impregnated shunt system was implanted after external drainage to prevent further infection.
0
Not-Related
An extensive literature search revealed few previous reports of herbal drug induced EM and SJS.
0
Not-Related
METHOD: Case report and review of the current literature concerning radiation-induced, secondary, space-occupying lesions.
0
Not-Related
Cefoxitin should either be used with great caution or not prescribed in combination with aminoglycoside antibiotics.
0
Not-Related
CASE SUMMARY: We report the case of a 31-year-old patient hospitalized due to behavioral alterations and treated with oral zuclopenthixol, an antipsychotic from the thioxanthene family, who developed an acute, painful erection.
1
Related
Glomerulonephritis in procainamide induced lupus erythematosus: report of a case and review of the literature.
1
Related
Childhood methanol ingestion treated with fomepizole and hemodialysis.
0
Not-Related
Two electrophysiological methods were performed for objective evaluation of retinal function, namely full-field electroretinography and multifocal electroretinography.
0
Not-Related
A review of the literature found 11 children and 2 adults in whom intranasal desmopressin was associated with hyponatremia, all of whom experienced seizures or altered mental status.
1
Related
Focal glomerulonephritis and interstitial nephritis in methicillin-treated, heroin-related infective endocarditis.
1
Related
Successful treatment with dantrolene does not, however, preclude a recurrence of MH, and thus subsequent doses of dantrolene should be given.
0
Not-Related
In 1 patient, pericardial effusion associated with a pseudoaneurysm was discovered in the operating room.
0
Not-Related
A diagnosis of visceral varicella-zoster disease was made, and early intravenous ACV therapy successfully alleviated the epigastric pain and skin lesions within 2 weeks.
0
Not-Related
To our knowledge, these cases are the first published reports of lovastatin-induced rhabdomyolysis associated with azithromycin and clarithromycin.
1
Related
The major side effect of infliximab is infection.
1
Related
One patient was treated symptomatically for the first 6 h until she was given dantrolene.
0
Not-Related
A patient presented with dilated cardiomyopathy after many years of overusing an adrenaline inhaler.
1
Related
For example, the potent CYP2D6 inhibitor fluoxetine increases the plasma concentrations of tricyclic antidepressants.
0
Not-Related
Discontinuation of ergot-containing products and cessation of tobacco and caffeine use is the cornerstone of therapy in chronic ergot toxicity.
0
Not-Related
This case demonstrates the importance of screening electrocardiograms, even in healthy young patients.
0
Not-Related
We report a case of baclofen withdrawal syndrome resulting from oral baclofen underdosing.
1
Related
The latter form (Macrodantin) is reported to engender less gastrointestinal intolerance but it can produce the same adverse effects as the conventional form--liver damage, acute and chronic pulmonary reactions, peripheral neuropathy, blood dyscrasias and allergic reactions--and does so just as rapidly and floridly; one such case is reported here.
1
Related
Moreover special caution with treatment of leishmaniasis must be taken in renal transplant because of possible interactions between antimony compounds and ciclosporin metabolites.
0
Not-Related
Lithium-associated transient thyrotoxicosis in 4 Chinese women with autoimmune thyroiditis.
1
Related
CASE SUMMARY: A 77-year-old white woman presented to the hospital with elevated serum creatinine, oliguria for the past 24 hours, arthralgia, fatigue, fever, and bilateral flank pain.
0
Not-Related
Lovastatin-induced rhabdomyolysis possibly associated with clarithromycin and azithromycin.
1
Related
In both cases, spontaneous resolution occurred over several weeks following withdrawal of the drug.
0
Not-Related
Pseudoephedrine-induced hemorrhage associated with a cerebral vascular malformation.
1
Related
Lymphotropic herpesviruses such as human herpesvirus type 6 (HHV-6) have enhanced pathogenicity in some immunocompromised hosts, such as transplant recipients and HIV-infected patients.
0
Not-Related
During admission she was found to be profoundly hypothyroid despite being on adequate thyroid replacement therapy.
0
Not-Related
Four recovered fully within 24 h, two recovered partially after 24 h and completely after 48 h while two recovered only after 72 h.
0
Not-Related
To our knowledge, this is the first case of griseofulvin-exacerbated lupus in which nephrotic syndrome has been observed.
1
Related
BACKGROUND: To describe the occurrence of ocular hypertension in four patients following injection of ranibizumab intravitreally.
1
Related
Other thiazolidinediones currently in clinical trials may be able to provide the therapeutic benefits of troglitazone without significant hepatotoxicity.
1
Related
Pneumonitis is emerging as one of the most unpredictable and potentially serious, adverse effects of treatment with MTX.
1
Related
With aggressive supportive therapy, including hypertonic saline administration and hemodialysis, the patient fully recovered without detectable sequelae.
0
Not-Related
A unilateral fixed and dilated pupil was noted.
0
Not-Related
Hepatotoxicity induced by cyproterone acetate: a report of three cases.
1
Related
Acute spontaneous tumor lysis syndrome in a patient with Crohn's disease taking immunosuppressants.
0
Not-Related
She was receiving several anti-tubercular drugs, including rifampicin, isonicotinic acid hydrazide (INH), pyrazinamide, and ethambutol, for abdominal tuberculosis.
0
Not-Related