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It is reversible with discontinuation of drug and administration of corticosteroids.
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A single-pass tunneling technique for CSF shunting procedures.
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These changes were associated temporally with cyproheptadine dosing.
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Capillary leak syndrome (CLS) commonly occurs in the intensive care setting.
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Hyperinfection with strongyloides following treatment with systemic steroids explains the presence of eosinophilia and splenic involvement.
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Knowledge of this interaction and adjustment of the dose of phenytoin should enable clinicians to avoid this adverse drug interaction.
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It is important for clinicians to recognize beta-lactam-induced leukopenia and maybe recommend use of a drug from a different antibiotic class if continued treatment is indicated.
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De novo absence status is a specific epileptic condition that should be suspected in all elderly subjects on chronic treatment with psychotropic drugs presenting in a confusional state.
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Intravenous mitozantrone was given for 2 years and she is asymptomatic, with computed tomographic evidence of tumour response, 27 months after diagnosis.
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The main clinical features of this 58-year-old female patient were laboratory evidence of leucopenia and cholestasis, and biopsy features of fatty liver parenchyma degeneration with granulocytic portal infiltration and bile stasis, demonstrated 20 days after the initiation of antithyroid therapy with 20 mg methimazole daily.
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Discussion includes a review of the literature with respect to the relative merits of daily oral cyclophosphamide versus pulse intravenous cyclophosphamide in WG and other vasculitides.
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This pediatric case report describes a massive overdose without significant side effects, thus suggesting a beneficial therapeutic index in pediatric patients.
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Syringotropic hypersensitivity reaction associated with infliximab and leflunomide combination therapy in a child with psoriatic arthritis.
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Although major hazards of treatment of hypophosphatemic osteomalacia with phosphate and calcitriol are secondary hyperparathyroidism and vitamin D intoxication, potassium loss also should be kept in mind.
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RESULTS: Complete thrombosis of the mycotic aneurysms was achieved in all patients.
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Experimental therapeutic approaches focus on the restitution of microcirculation (endothelin receptor antagonists, atriopeptins), interference with cast formation (integrin receptor blockers), and the promotion of recovery by growth factors.
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GVHD occurs when immunologically active T lymphocytes are transplanted into an immunosuppressed recipient who is genetically disparate from the donor.
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Robust guidelines and highlighting patients with risk factors are required to prevent this complication from recurring.
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These features are similar to those observed previously in persistent light reactors to topical photosensitizers.
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To avoid that toxicity, a new weekly schedule has been adopted in several Phase II studies.
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Concomitant use of statins and cyclosporine should be avoided.
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In this paper, we report a case of severe hypercalcemia of immobilization in a 40-year-old hemodialyzed woman treated by cinacalcet HCl for a severe HPTH-II (PTH>1,000 pg/mL).
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The unmedicated eye remains asymptomatic to date.
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Though physicians treating large populations of patients with HIV are well aware of this complication, only one other report of nevirapine-associated SJS has been documented in the dermatology literature.
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When there was no laboratory confirmation of the arteritis, an iatrogenic etiology (ergotism) was suspected.
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Hyperosmolar hyperglycemic nonketotic coma is a serious and often lethal clinical biochemical syndrome.
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The mean +/- SD decrease in VAS at this time was 61.2 +/- 15.5%.
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Neurologic manifestations of HIV infection are quite diverse and can develop into seizures.
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After treatment for five months on this therapy, he presented with new-onset atrial fibrillation.
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Bortezomib-induced paralytic ileus is a potential gastrointestinal side effect of this first-in-class anticancer proteasome inhibitor.
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Painful erosion of psoriatic plaques is a less common sign of methotrexate toxicity that may precede evidence of bone marrow suppression.
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This case may be an example of cryptogenic form of reflex epilepsy with seizures induced exclusively by tooth brushing.
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However, serum HBV DNA turned detectable again after 9 months of LAM therapy and a YMDD mutation was detected.
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His wound cultures continued to be negative.
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Successful use of oral ganciclovir for the treatment of intrauterine cytomegalovirus infection in a renal allograft recipient.
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As far as we know, this is the first report in English literature indicating such an adverse effect of pegylated interferon alpha.
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After 582 allogeneic bone marrow transplants, we have encountered four patients (0.7%) who developed transient unilateral or bilateral sixth nerve palsies.
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Photopatch tests to 1% mequitazine with 5 J/cm2 of UVA in 30 normal subjects were all negative, which means that 1% concentration may be appropriate for the photopatch test.
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Seven patients, five male and two female (mean age 75.3+/-4.7 years, range 68-81), diagnosed with DLB were treated with the acetylcholinesterase inhibitor donepezil (5-10 mg once daily) to determine its effect on treating behavioural disorders.
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OBJECTIVE: Traditional monoamine oxidase inhibitors (MAOIs) continue to play an important role in the management of a wide variety of clinical conditions.
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A patient receiving allogeneic bone marrow transplant for treatment of acute myelomonocytic leukemia died on the 78th post-transplant day with clinically unrecognized disseminated histoplasmosis.
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Four previously reported cases with the same sequence of events are reviewed as well as cases of chronic myelogenous leukemia following chemotherapy alone.
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Air conditioning and proper ventilation of the operating room, the use of coolant sprays, good suction and proper handling of amalgam waste is recommended.
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When high dose leucovorin was not used, residual neurological damage is not unusual.
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In case no. 2, the pathogenic mechanism seemed to be persistent light reaction preceded by systemic photoallergy, as he had taken mequitazine for 6 months, and there were strong positive photopatch test results with immediate erythema reaction, cross-reaction to promethazine, decreased MED to both UVA and UVB, and persistence of the photosensitivity over a 3-year follow-up period after discontinuation of the mequitazine.
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It was confirmed histologically.
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MR of the brain was performed in eight patients (mean age, 14.9 years) with osteogenic sarcoma during or after IV treatment with high-dose methotrexate.
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Malignant neoplasm after immunosuppressive therapy is a well-known entity.
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A rechallenge, performed in both patients, confirmed the diagnosis of mesalamine-induced pancreatitis.
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CASE SUMMARY: A 65-year-old patient chronically treated with the selective serotonin reuptake inhibitor (SSRI) citalopram developed confusion, agitation, tachycardia, tremors, myoclonic jerks and unsteady gait, consistent with serotonin syndrome, following initiation of fentanyl, and all symptoms and signs resolved following discontinuation of fentanyl.
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CONCLUSION: Healthcare professionals should be aware of the possible development of serotonin syndrome as a complication of initiation of fentanyl and other phenylpiperidine opioids in patients treated with SSRIs.
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This case documents the first report in the otolaryngology literature describing this new etiology for nasal septal perforations.
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Three were not assessable.
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Porcine factor VIII (pFVIII), which is used to control bleeding in patients with congenital or acquired haemophilia who have high-titre neutralizing antibodies to human FVIII, is not known to increase the risk of arterial or venous thrombosis.
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Two months later, hyponatremia was diagnosed, most likely syndrome of inappropriate antidiuretic hormone secretion.
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As the disfiguring lesions had a marked adverse effect on her quality of life, a trial of IV Cidofovir was instituted.
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Desquamative interstitial pneumonitis complicating inflammatory bowel disease of childhood.
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Caution in the use of boldo in herbal laxatives: a case of hepatotoxicity.
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This is the first reported case of hepatolithiasis during octreotide therapy.
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Report of a case and review of the literature.
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We report three cases of IFN beta induced hepatitis in MS and discuss the pathology findings and possible mechanisms of drug-induced liver injury.
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In renal transplant patients living in endemic countries, visceral leishmaniasis should be kept in mind as a potential cause of unexplained long-standing fever and considered as an opportunistic infection.
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These findings are consistent with an immune-complex form of glomerulopathy in which gold is neither the antigen nor a hapten in the glomerular deposits, and they suggest the hypothesis that antibodies to tubular epithelial antigens induced by gold therapy may be a causative factor in the renal disease associated with gold therapy in rheumatoid arthritis.
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His clinical course and laboratory studies are discussed.
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At this time most of the DGTX in serum was FAB-bound.
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Mammographically the malignant microcalcifications appeared only in the region of the breast where the primary tumor was found.
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One patient also manifested marked disinhibited and disruptive sexual behavior.
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Two of the three cases had received blood transfusions, and attention is drawn to the possibility that mitomycin C may sensitise the kidneys to minor mismatches.
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Combined intoxication with a tricyclic antidepressive agent and a neuroleptic.
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Treatment was modified, symptoms resolved in 1 to 2 weeks, and the white-matter changes resolved over 6 to 12 months.
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Based on newly published data we have applied an infusion of both compounds, 5-FU and calcium folinate, mixed together in an ambulatory pump.
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The patient's platelet count dropped rapidly to a level of 1000/mm3 after receiving a single 600 mg dose of rifampin.
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Catecholamine treatment for hypotension is common practice in neonatal intensive care units.
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Contact dermatitis treated with new topical products: a case study.
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Six patients with no previous signs or symptoms suggestive of coronary artery disease developed acute coronary ischemia/infarction shortly after cis-diamine-dichloroplatinum II (cisplatin) -based chemotherapy.
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Infant twins sustained severe circumoral and pharyngeal burns from a concentrated solution of benzalkonium (Zephiran) chloride prescribed for treatment of candidiasis.
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He had been taking trimethoprim-sulfamethoxazole for approximately eight days when he revisited his family physician, complaining of headaches, dizziness, difficulty with speech, weakness, and itching on the trunk of his body and legs, where a maculopapular rash was noted.
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The benefit of apomorphine on sexual function in some patients suggests a possible role in the treatment of impotence in PD.
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Cultures of the cornea tissue and contact lens storage solution both grew Serratia Marcescens, which was sensitive to ciprofloxacin.
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This case report raises one more time the question about the safety of the LORA technique for labor analgesia.
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BACKGROUND: Ovarian cancer arising from an endometriotic cyst in a postmenopausal woman under tamoxifen therapy is rare.
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Despite minimal short-term side effects and apparent efficacy, chronic treatment of MG with MM may be associated with increased risk of lymphoproliferative disorders.
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Adenomyosis confined to the broad ligament is extremely rare.
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Based on these survival data the administration of concomitant cisplatin and radiotherapy has become standard of care for nasopharyngeal carcinoma in the USA.
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BACKGROUND: To assess the nature, incidence, and risk factors of retinopathy associated with pegylated interferon and ribavirin combination therapy in chronic hepatitis C patients.
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Metabolic imbalance appears as the leading aetiology, among several other hypotheses.
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The relationship between chronic inflammatory conditions and malignancy is complex.
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A new alkaline propanolamine derivative, enciprazine, was tested in an early phase-II semi double-blind placebo-controlled A-B-A design to verify the hypothesis that the substance may have tranquilizing properties.
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A complex pattern of melanonychia and onycholysis after treatment with pemetrexed for lung cancer.
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CASE SUMMARY: A 35-year-old African American woman with a history of primary pulmonary hypertension managed with warfarin, diltiazem, and hydrochlorothiazide was initiated on bosentan therapy.
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After intravenous antibiotic treatment, the infection resolved with full restoration of visual acuity and ocular motility.
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Neuroleptic-induced panic attacks in a patient with delusional depression.
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Our patient had headache, mild fever, nausea, vomiting, rash, and eosinophilia after 3 weeks of disulfiram therapy.
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The area healed slowly over 7 weeks, but there was a residual loss of cutaneous sensation.
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The use of an indium111 DTPA flow study in the evaluation of a lumbar swelling in a girl with a baclofen pump.
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One of the cases involved a 72-year-old woman who died with Salmonella enteritis and sepsis that had not responded to treatment with chloramphenicol.
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We report a case of coagulation activation, fluid retention and transient autoimmune hepatitis most likely triggered by the use of black cohosh.
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A patient receiving vancomycin for a serious staphylococcal infection had a lupus-like syndrome characterized by a malar rash, pain and erythema of the cartilage of both ears, and tender erythematous and hemorrhagic lesions of the finger tips.
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Respiratory distress, severe VOD and grade II acute gastrointestinal GVHD complicated the post-transplant period.
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METHODS: A case report of a patient with ovarian cancer extensively treated with platinum-based chemotherapy and aggressive surgery is presented.
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