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This case describes fulminant hepatic failure in a patient taking disulfiram with no previous liver disease and report of being compliant with alcohol abstinence.
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Lithium (Eskalith) is commonly used in the treatment of depressive and bipolar affective disorders, in a population at relatively high risk for overdose.
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INTRODUCTION: Visual loss is a rare complication of tuberculosis; it can be related to anti-tuberculous drugs or to the infection itself.
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Palpable purpuric skin lesions on the anterior surface of both legs appeared on the 55th day of amphotericin B treatment.
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Urine glucose and single afternoon blood glucose determinations were inadequate and potentially misleading in monitoring diabetic cats receiving excessive amounts of insulin.
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Surveillance in the intensive care unit is mandatory during readministration of the drug.
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A case report of a patient with probable cisplatin and bleomycin-induced TMA is presented.
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The patient presented with headache, left facial and orbital pain, nasal discharge, and elevation of serum creatinine 18 months after kidney transplantation.
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Our purpose is to highlight the dangerous means adopted by unlicensed medical charlatans to induce abortion as well as to emphasize the key role played by anesthesiologists in the management of such cases.
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However, peripheral neuropathy and bone marrow depression led to linezolid withdrawal in seven patients, and neuropathy may not be fully reversible in all patients.
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Hepatic Sinusoidal Obstruction Syndrome in a child after chemotherapy for medulloblastoma.
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The patient was then dialyzed for presumed acyclovir toxicity.
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We observed 3 diabetic patients with intolerable dizziness followed by nausea and vomiting immediately after an initial administration of the alpha-glucosidase inhibitor, voglibose.
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Complete clinical-electroencephalographic recovery was achieved after lithium therapy was discontinued.
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Currently the use of zidovudine is one of the few specific measures available, and as a potentially teratogenic and fetotoxic agent, any decision for its use requires evaluation of the potential for fetal damage.
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High-dose intravenous mannitol infusion in various clinical settings may result in acute renal failure (ARF).
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PURPOSE: To investigate the concentration-side effect relationship in a patient with severe acyclovir-induced neurotoxicity and to summarize the information available in the literature about central nervous system side effects due to acyclovir.
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Effect on levels of intercellular antibodies in pemphigus vulgaris.
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BACKGROUND: A 68-year-old man diagnosed with primary plasma-cell leukemia was given thalidomide maintenance treatment for his disease.
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BACKGROUND: Visceral leishmaniasis is a protozoan infection usually asymptomatic, but can progress to fatal disease in immunocompromised hosts, especially in HIV patients.
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Liver abscess in patients with a VP shunt should be considered a possible abdominal complication of the VP shunt, and may be caused by unusual pathogens.
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We report 2 cases of maculopapular eruption and fever in patients infected with human immunodeficiency virus (HIV) on the 2nd day of first administration of ritonavir, a protease inhibitor.
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Bone injury while undergoing electro-convulsive therapy is thought to be rare.
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Metastatic osteomyelitis following BCG vaccination.
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Symptomatic hypoglycemia secondary to a glipizide-trimethoprim/sulfamethoxazole drug interaction.
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We report a patient with a recurrent supratentorial pilocytic astrocytoma who had an untoward interaction between high-dose tamoxifen therapy and phenytoin (PHT), drugs that share a common enzyme for metabolism, therefore emphasizing the need to monitor concomitant antiepileptic drug (AED) levels when high-dose tamoxifen therapy is instituted.
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Laboratory abnormalities included a prothrombin time < 10%, an international normalized ratio exceeding the laboratory limits, and an activated partial thromboplastin time >120 seconds.
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We explored ophthalmic and neurologic findings in two children who have been exposed prenatally to VGB.
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Captopril is known to be associated with dermatologic, hematologic, and pulmonary adverse effects.
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We report a 45-year-old psoriasis patient who developed eruptive mollusca contagiosa during an antipsoriatic treatment with efalizumab.
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An intertrigo-like eruption from pegylated liposomal doxorubicin.
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MK-0457, a novel kinase inhibitor, is active in patients with chronic myeloid leukemia or acute lymphocytic leukemia with the T315I BCR-ABL mutation.
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We describe a patient who presented with bloody diarrhoea after 15 mg meloxicam daily for 10 days for osteoarthritis.
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She was administered metoclopramide because of nausea and, within 2 hours, developed agitation, dysarthria, diaphoresis, and a movement disorder.
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Histological examination of liver biopsies showed diffuse microvesicular steatosis.
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Camptocormia, a new side effect of sodium valproate.
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An interaction between cytostatic and anticonvulsant drugs.
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This case report describes the use of a Q-switched neodymium:YAG laser to puncture miotic cysts.
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This is the first report of non-convulsive status epilepticus provoked by tiagabine in adolescent patients.
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In contrast, none of 27 nondiabetic healthy normal controls or 10 diabetics who had never received protamine or protamine-containing insulin had levels of antiprotamine immunoglobulin E over background.
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In the present study, we present three cases in which patients with resistant schizophrenia and comorbid alcohol use disorder were given lamotrigine to augment clozapine.
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The aim of this report is to describe the clinical and electroencephalographic findings seen in an elderly woman without previous history of seizures who developed a nonconvulsive generalized status epilepticus following acute withdrawal of lorazepam.
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Resolution of protein-losing enteropathy and normalization of mesenteric Doppler flow with sildenafil after Fontan.
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The tryptase sera level was 109 mg/L one hour after the reaction had subsided, while the basal values were normal.
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The authors describe a patient with hemiparesis who developed the syndrome of irreversible lithium-effectuated neurotoxicity (SILENT) while being treated with lithium for a manic episode.
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Burn of the auricle.
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Liver biopsy showed intralobular inflammatory infiltrates, confluent necrosis and apoptosis, compatible with drug-induced liver disease.
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His medical history included ischemic cardiomyopathy, pacemaker placement, ESRD, carotid artery disease, and type 2 diabetes mellitus.
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Furthermore, beneficial or harmful effects of steroids in eosinophilic jejunitis and its treatment details are discussed and reviewed.
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Cytomegalovirus pneumonia in a patient with breast cancer on chemotherapy: case report and review of the literature.
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Large part of these nodules were suspected to be well differentiated hepatocellular carcinoma with high level of serum alpha-fetoprotein (AFP) up to 3,400 ng/ml, but a part of them was evaluated to be a borderline between hepatocellular carcinoma and adenoma with mild cellular atypism.
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Various medical treatments had been tried with meager results.
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A 66-year-old woman had a sudden onset of small-bowel obstruction during enzymatic treatment for gastric persimmon bezoar.
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RESULTS: After a prolonged postoperative course, including administration of topical ofloxacin, tobramycin, chloramphenicol, and dexamethasone, UCVA returned to 20/20.
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Treatment of chronic hepatitis C with interferon alpha (IFN-alpha) is relatively contraindicated in patients with psychiatric disorders because of possible severe psychiatric side effects.
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A fatal pancytopenia occurred in a patient with an history of depression with hypomanic rebounds, admitted for a manic episode and treated with levomepromazine, diazepam and lithium carbonate.
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Acute myopathy with selective degeneration of myosin filaments following status asthmaticus treated with methylprednisolone and vecuronium.
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Valproate, hyperandrogenism, and polycystic ovaries: a report of 3 cases.
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A 45-year-old woman with steroid-dependent Crohn's colitis, successfully managed with maintenance infliximab infusions and methotrexate, developed a lupus-like syndrome eight months after her initial infusion.
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Here we present the case of a generalized lichen nitidus with involvement of the palms in a patient with hepatitis C after systemic treatment with interferon alpha and ribavirin.
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RESULTS: Findings and course were typical for the recently described progressive outer retinal necrosis syndrome.
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In addition to the recognized arrhythmic complications, the authors emphasize myocardial necrosis as a possible further manifestation of amsacrine-related cardiotoxicity.
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Its use, together with other techniques, such as mycologic, cytologic and histological examinations, allowed us to identify Candida albicans as aetiological agent in this particular case.
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DATA SYNTHESIS: Genetic deficiencies in DPD, the rate-limiting enzyme responsible for 5-FU catabolism, may occur in 3% or more of patients with cancer putting them at increased risk for unusually severe adverse reactions (e.g., diarrhea, stomatitis, mucositis, myelosuppression, neurotoxicity) to standard doses of 5-FU.
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A variety of movement disorders are known to occur in association with carbamazepine (CBZ) therapy in adults and children, but development of tics has been described infrequently and only in patients with underlying Tourette's syndrome or other movement disorders.
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The Jarisch-Herxheimer reaction in ocular syphilis.
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Camptocormia occurred concomitantly with an increase of the plasma valproate level from about 330 mumol/l up to 530 mumol/l.
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After three weeks of carbamazepine therapy, the patient arrived at the emergency department (ED) with severe agitation and aggressive behavior.
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He underwent five sessions of plasmapheresis.
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Serum aluminum levels were significantly (P less than 0.001) higher in these 3 infants and in 1 other, all of whom received more than 100 mg of elemental aluminum per kilogram of body weight per day (mean +/- S.D., 371.0 +/- 178.9 ng per milliliter [13.75 +/- 6.6 mumol per liter] ) than they were in 8 older children with azotemia who were not undergoing dialysis and who received less than 100 mg of elemental aluminum per kilogram per day (27.0 +/- 18.6 ng per milliliter [1.0 +/- 0.68 mumol per liter] ), 7 such children who did not receive aluminum hydroxide (20.28 +/- 9.2 ng per milliliter [0.75 +/- 0.34 mumol per liter] ), and 16 children with normal renal function (21.04 +/- 4.9 ng per milliliter [0.78 +/- 0.18 mumol per liter] ).
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The first case of keratitis caused by Nocardia exalbida.
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With the first cyclosporine dose, the patient complained of leg pain that was most severe during the cyclosporine infusion.
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Rapamycin/sirolimus (SR), trade named Rapammune (Wyeth-Ayerst, Sydney, Australia), is a potent immunosuppressive drug associated with myelosuppression, hypertension, hyperlipidemia, and infection.
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A 57-year-old woman with right bundle branch block +LPH and ventricular premature contractions developed complete heart block (CHB) following administration of disopyramide phosphate (Norpace).
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METHODS: We present the clinical findings, pertinent laboratory data, and follow-up course of a patient with Graves' disease and bilateral sensorineural hearing loss.
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Precursor prothrombin status in two mother-infant pairs following gestational anticonvulsant therapy.
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Serum samples were collected throughout the infectious process for viral DNA analysis.
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His electrocardiogram revealed minor abnormalities, including a prolonged QT interval.
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This agent has severe teratogenic effects, as serious craniofacial, cardiovascular, thymic and central nervous system malformations.
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TSH remained persistently raised and the patient became thyrotoxic.
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CASE REPORT: We report a case of intracerebral hemorrhage occurring in a middle-aged man who suffered from chronic sinusitis and had been ingesting pseudoephedrine daily for one year.
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The patient's defects may be due to methimazole teratogenicity or could represent a previously undescribed syndrome affecting ectodermal structures.
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Early detection of these cases has practical importance since the identification and elimination of the causative drug is essential for therapy success.
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Treatment of chronic hepatitis C with interferon alpha (IFN-alpha) is relatively contraindicated in patients with psychiatric disorders because of possible severe psychiatric side effects.
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Endoscopic management of a new entity-plastobezoar: a case report and review of literature.
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Cardiac arrest associated with sulprostone use during caesarean section.
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Two patients died.
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Dopamine dysregulation syndrome in a patient with restless legs syndrome.
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This case may start a debate on the susceptibility of central nervous system tumors following chemotherapy in patients with ITO.
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Ultrasonography showed ciliochoroidal effusion.
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We report on a 64 year old patient with a severe flare-up of UC who responded well to intravenous CyA after a standard therapy with high dose corticosteroids alone had been ineffective.
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The case of a 4-year-old girl with valproate-induced stupor and electroencephalographic pattern of increased fast activity is reported.
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Two female patients presented nodular erythematous lesions overlying a permanent tattooed eyebrow and lip, respectively.
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Transoesophageal echocardiography (TEE) was performed which showed a multilobulated liquid-filled mass (3.6 x 3.7 cm), adherent to the septal, anterior and posterolateral LA most consistent with thrombosis.
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BACKGROUND: Reproductive endocrine disorders characterized by menstrual disorders, polycystic ovaries, and hyperandrogenism seem to be common among women treated with sodium valproate for epilepsy.
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OBJECTIVE: To describe a case of exacerbated mania potentially related to an interaction between lopinavir/ritonavir and valproic acid (VPA) and propose a mechanism of action for this interaction.
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Before retreatment, the best corrected visual acuity (BCVA) ranged from 20/40 to 20/200.
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Daily measurements of pulse, blood pressure, temperature and various laboratory examinations were carried out.
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A case of bullous pemphigoid in a patient on hemodialysis.
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In the early postoperative period, pulmonary thromboembolism was suspected and confirmed by lung perfusion scintigraphy which showed bilateral segmental and subsegmental perfusion defects.
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