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Fatal fluoxetine ingestion with postmortem blood concentrations.
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To eradicate the infection, we performed two vitrectomies and treated the patient with numerous intravitreal antibiotic injections.
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Because the maximum tolerated dose and pharmacokinetics of intravenous iron preparations are not known, their use in both adults and children should still be undertaken with caution.
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The baseline population risk of malformations is 3-5%, but it increases to almost 30% in women exposed to isotretinoin during the first trimester of pregnancy.
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Psoas abscess following ileo-anal pouch surgery.
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This unprecedented phenomenon may be due to antiretroviral therapy.
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The renal biopsy showed focal segmental glomerulosclerosis, which has only been previously reported in two cases of CML treated with IFNalpha.
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An objective causality assessment revealed that the adverse drug event was probable.
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The development of systemic lupus erythematosus (SLE) after 38 months of therapy with recombinant human interferon gamma (rIFN-gamma) was observed in a patient with rheumatoid arthritis.
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All children showed a major clinical improvement within three months despite concomitant reduction of the prednisone dose.
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Nine days later, severe abdominal pain developed.
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In each case, the decline in free SDC was temporally related to the resolution of digoxin toxicity; in one case, digoxin intoxication recurred and was associated with a rebound increase in free SDC.
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The long-acting somatostatin analogue octreotide (LAR, 30 mg/month, i.m.), was started, and after 2 weeks diarrhea decreased and gradually disappeared.
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CONCLUSION: The new quinolone derivatives (levofloxacin, sparfloxacin, grepafloxacin, trovafloxacin, gatifloxacin and moxifloxacin), also called gyrase inhibitors, are known for their potential to cause central nervous system-related adverse effects, including headache, dizziness and insomnia.
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It emphasizes the need for close surveillance of renal function and blood pressure during such therapy even in patients with relative preservation of renal function.
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After positioning of a 0.035 inch guidewire proximal to the biliary stricture, the preloaded catheter was advanced over the guidewire by using the monorail technique.
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Careful donor evaluation before transplantation, unusually early presentation of mycosis leading to anastomotic renal artery disruption, the histopathologic findings of the grafts, and the absence of Candida infection in the liver and heart recipients make us believe that exogenous contamination of the grafts occurred during donor procedure, kidney processing, or at transplantation.
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Three patients never had intubation during hospitalization.
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The patient developed abdominal pain and high fever on Day 21 after the initiation of chemotherapy.
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This is the first described case of acute gouty arthritis after RFA for a HCC lesion in a patient with underlying chronic renal insufficiency.
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The elicitation of a movement disorder by trazodone: case report.
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Intrathecal chemotherapy with methotrexate or cytosine arabinoside is the standard approach to prophylaxis and treatment of central nervous system leukemia in children.
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The spectrum of antimicrobial activity of albendazole and its efficacy in the treatment of intestinal microsporidiosis are reviewed.
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CONCLUSION: Patients receiving inhaled morphine should be closely monitored and resuscitation equipment should be readily available.
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When the patient was treated again with fludarabine nine months later, the DAT became positive with anti-IgG and anti-C3d antiglobulins after the second course of treatment.
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All biopsies were studied by the same pathologist.
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The isotretinoin, a 13-cis-retinoic acid, has revolutionized the management of severe treatment-resistant acne and it has been widely used for a range of dermatological conditions, in 90% of the time in young women between 13 and 45 years of age.
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In three patients, occasional transient episodes of atrial flutter or atrial fibrillation preceded a spontaneous return to normal sinus rhythm.
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Hyperammonemia has been described as a complication of valproic acid therapy but may often be overlooked as a cause of lethargy in the postictal patient who presents to the emergency department.
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Dyspnea, hypoxemia, and pleuritic chest pain occurred within 24 hours of rituximab administration, and there was no other apparent explanation.
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Cisplatin administration following carboplatin desensitization failure in primary peritoneal cancer: a brief report.
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The increasing number of doses administered worldwide has revealed rare but important adverse effects that had not occurred during clinical trials.
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We present a case of acute epinephrine toxicity resulting in acute myocardial ischemia in a young boy with combined variable immunodeficiency syndrome who developed severe allergic reaction to intravenous immunoglobulin, and was subsequently given epinephrine by mistake intravenously rather than subcutaneously.
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CASE SUMMARY: A 65-year-old patient chronically treated with the selective serotonin reuptake inhibitor (SSRI) citalopram developed confusion, agitation, tachycardia, tremors, myoclonic jerks and unsteady gait, consistent with serotonin syndrome, following initiation of fentanyl, and all symptoms and signs resolved following discontinuation of fentanyl.
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We encountered two cases of acute pancreatitis in patients with Cushing's disease following transnasal transsphenoidal hypophysectomy.
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In contrast to two other reported cases, our patient was not overtly immunosuppressed.
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OBJECTIVE: The purpose of this study was to report the concomitant occurrence of multiple squamous cell carcinomas and diffuse nail hyperpigmentation associated with hydroxyurea treatment, and to describe a successful therapeutic approach using imiquimod 5%.
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Infiltrative ophthalmopathy and primary hypothyroidism: a rare clinical manifestation of a common disease.
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This side effect appears to be a universal property of effective antidepressants, including this new, purely serotonergic agent.
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Treatment of acute necrotizing pancreatitis (ANP) after TACE is the same as the accepted approach to ANP due to other causes.
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Dysphagia, though uncommon, can be quite debilitating and can mimic a paraneoplastic syndrome.
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Overdose of magnesium sulfate in combination with renal insufficiency, hypocalcemia, or compromise of intestinal integrity may predispose horses to magnesium toxicosis.
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Biopsy specimens showed atypical lymphoid cell infiltration.
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Propylthiouracil-induced sensorineural hearing loss associated with antineutrophil cytoplasmic antibodies.
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Standard PSG recording and scoring methods were employed.
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An unusual complication of a Hickman catheter.
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The reaction was thought to be triggered by the combination of radiation and epidermal growth factor receptor tyrosine kinase inhibitors, which may be responsible for hypersensitizing the radiation response in normal tissue in the unique individual.
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Antimycobacterial treatment, which led to a dramatic improvement within two months, was protracted for 18 months until the complete return to normal of both clinical and laboratory findings.
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The possible causal relationship between prolonged estrogen administration and breast cancer in males is in contrast to available epidemiologic data.
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We here report on 3 patients with essential tremor, otherwise unresponsive to pharmacological treatment, who greatly benefited from low doses of topiramate (50 mg/d).
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He was subsequently followed on a regular basis with repeated measurement of lead levels in blood and bone (using a K-x-ray fluorescence instrument) as well as clinical parameters.
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Despite treatment with corticosteroids, she had rapid deterioration and died of respiratory failure.
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Profound muscle weakness of lower extremities with inability to stand up and/or walk was present.
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Because corticosteroids may induce several psychiatric symptoms, psychotropic drugs are required to treat these symptoms in some cases.
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Azathioprine withdrawal resulted after 7 weeks in the resolution of clinical and biochemical abnormalities.
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All the lesions showed high attenuation relative to muscle on the precontrast CT and showed positive findings on PET/CT.
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He was initially diagnosed with chronic lymphocytic leukemia (CLL) and treated with six cycles of fludarabine, cyclophosphamide, and rituximab chemotherapy.
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Rapid onset of muscle weakness (rhabdomyolysis) associated with the combined use of simvastatin and colchicine.
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Chronic inflammatory demyelinating polyneuropathy associated with tumor necrosis factor-alpha antagonists.
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Amphotericin B-induced cutaneous leucocytoclastic vasculitis: case report.
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Prophylactic administration of thiabendazole is probably preventive.
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Necrotizing leukoencephalopathy and treated multiple myeloma.
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Liposomes have been proposed as an effective way to target drugs at macrophages, which are the cells infected in visceral leishmaniasis.
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A case of polymyositis with dilated cardiomyopathy associated with interferon alpha treatment for hepatitis B.
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We treated her hyperthyroidism with amiodarone (average daily dose, 200 mg) for 3 weeks, achieving rapid and persistent euthyroidism, (triiodothyronine [T(3)] levels ranged between 64 and 109 ng/dL) without side effects.
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Hepatic damage after danazol treatment.
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We describe a 57-year-old woman with acute lymphoblastic leukemia who had a cavitary lesion develop in the right upper lobe caused by Cunninghamella bertholletiae, a zygomycete.
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It was highly suspected that finasteride was associated with the anterior subcapsular opacity on the lens, and the patient therefore discontinued use of finasteride.
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We report two cases of uncommon pathological reactions, one resembling a hypersensitivity pneumonitis and the other mimicking a giant cell interstitial pneumonia.
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The mechanisms are not clear, and peripheral (case 1) and also central pathways (case 2) could be involved.
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For all recipients with neurologic complications, we reviewed clinical findings, imaging and electrophysiologic test results, and perioperative laboratory data.
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Fatal exacerbation of paraneoplastic systemic sclerosis after neoadjuvant chemotherapy in a breast cancer patient.
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We report a case of pancytopenia in a 23-year-old man with Crohn's disease who was treated with 5-aminosalicylic acid (Pentasa; Nisshin, Tokyo, Japan) 3.0 g/day.
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Near fatal acute colchicine intoxication in a child.
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Prevention, early recognition of the clinical presentation, identification and removal of the offending agents, supportive care, and specific pharmacologic therapy are all important to the successful management of serotonin syndrome.
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We describe a case of an NHL patient who received rituximab and developed symptomatic, biopsy-proven multinodular bronchiolitis obliterans with organizing pneumonia (BOOP).
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The possible effects of tamoxifen upon the uterus are discussed in this article, in view of reports of tamoxifen associated with endometrial carcinoma and endometriosis.
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During clarithromycin coadministration, four out of the seven patients developed moderate-to-severe toxic symptoms of carbamazepine, such as drowsiness, dizziness, and ataxia, which resolved within 5 days after clarithromycin discontinuation.
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All patients underwent radiological investigation for tumour staging and comparison with the following study in accordance with the protocol in place at our Department of Oncology and Division of Diagnostic Imaging.
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Histopathological features were also consistent with the disease.
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We describe a patient who presented with autoimmune hemolytic anemia and small bowel obstruction secondary to a malignant stromal tumor (leiomyosarcoma) of the jejunum, 25 years postchemotherapy and radiation treatment for stage IIA Hodgkin's disease.
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Opioid analgesics were the most common therapy (81%).
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A fatal case of theophylline intoxication.
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Reports on such manifestations in relation to hepatitis B vaccination are scarce, however.
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Iatrogenic hypercalcemia due to vitamin D3 ointment (1,24(OH)2D3) combined with thiazide diuretics in a case of psoriasis.
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Although follow-up is short, radiotherapy alone appears to provide excellent disease-free survival.
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These cases and a review of the literature suggested that hepatotoxicity, though rare, should be added to the list of adverse reactions to D-penicillamine.
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A few limited literatures about this disease strongly recommends steroid therapy for treatment.
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Abdominal pain and obstructive symptoms concomitant with weight loss are the common presenting complaints.
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First trimester disulfiram exposure: report of two cases.
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Rapamycin/sirolimus-induced pneumonitis has been described previously in renal transplant recipients, and this report describes a stable heart-lung transplant recipient who developed a pulmonary infiltrate that reversed after ceasing SR therapy.
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In studies addressing this issue, there appears to be no real problem with increased severe episodes of hypoglycemia in patients on beta-blockers or increased hypoglycemic unawareness.
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RESULTS: All seven children are alive and without evidence of tumor with a median follow-up of 30 months (range, 18-35 months) from diagnosis.
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Liver abscess caused by ventriculoperitoneal (VP) shunt is very rare.
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Rechallenge with a different beta-lactam antibiotic has not been shown to consistently cause recurrent leukopenia.
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Three case studies are the basis for a discussion of the criminalization hypothesis as it may apply to psychiatric probationers and parolees in the criminal justice system.
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The absence of eosinophils does not exclude the possibility of a minocycline cause.
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In all five patients, sodium loading was associated with improved renal function, which permitted amphotericin B therapy to be continued in fully effective doses to the completion of elective courses of treatment without evidence of residual impaired renal function.
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TREATMENT AND OUTCOME: The mare was treated with gabapentin (2.5 mg/kg [1.1 mg/lb], PO, q 12 h).
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Rechallenge with varenicline while the patient continued to receive amphetamine-dextroamphetamine yielded similar results.
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