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The patient recovered motor, sensory, and bowel and bladder function over the next 48 h.
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The oligohidrosis caused by zonisamide was reversible in that the patient regained the ability to sweat within 2 weeks of the cessation of drug administration.
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The clinical aspect closely resembled classical transient global amnesia but the episode after clioquinol lasted longer (24 hours to three days) and a more or less extensive retrograde amnesia persisted permanently.
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Higher MK-0457 dose levels were associated with clinical responses and down-regulation of CrkL phosphorylation in leukemia cells.
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Visual system side effects caused by parasympathetic dysfunction after botulinum toxin type B injections.
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The patient underwent coronary stenting without any immediate signs of complications.
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A 63-year-old man with a T1c adenocarcinoma of the prostate, Gleason score of 7 (4+3), and a pretreatment prostate-specific antigen (PSA) level of 9.5 ng/mL was treated with external-beam radiation therapy (45 Gy) and 2 magnetic resonance imaging-guided high-dose rate brachytherapy boosts (10 Gy each.) The patient also received neoadjuvant, concurrent, and adjuvant hormonal treatment with leuprolide for 7 months total.
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Complications of tumour overkill when associated with high dose methotrexate therapy.
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Temporal sequence of his signs and symptoms after each administration of tobramycin (similar to re-challenge testing), and his improvement after discontinuation of the drug strongly suggest an adverse drug reaction.
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CONCLUSION: Oral mucositis is a frequent and potentially severe complication of cancer chemotherapy.
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These adverse reactions were recognized early and the appropriate treatment of agranulocytosis resulted in complete recovery in both cases.
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A dapsone hypersensitivity syndrome, consisting of fever, headache, nausea, vomiting, lymphadenopathy, hepatitis, hemolysis, leukopenia, and mononucleosis, has been described in patients treated with the drug for leprosy.
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Benign thymic hyperplasia after chemotherapy for acute myeloid leukemia.
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Treatment of silastic catheter-induced central vein septic thrombophlebitis.
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Scleroderma-like reaction induced by uracil-tegafur (UFT), a second-generation anticancer agent.
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This report presents a patient with membranoproliferative glomerulonephritis (MPGN) who developed KS following treatment with long-term medium dose glucocorticoid and short-term additional immunosuppressives.
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Recent technical advances in infusion systems in the form of the infusaid pump has allowed delivery of chemotherapeutic agents to the liver with great reliability.
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Although adverse effects are mainly mild, more serious infrequent adverse effects including leucopenia are mentioned.
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One and a half years later, she is still alive and well, on interferon for persisting myeloma.
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CONCLUSIONS: Capecitabine and 5-fluorouracil (5-FU) are known vasospasm inducers.
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The first case had cytogenetic changes in the bone marrow suggestive of therapy-associated leukemia, and the second developed myelodysplastic syndrome on therapy which was likely chemotherapy-induced and led to acute leukemia.
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A second possibility is an interaction between clarithromycin and isradipine, potentially increasing the hepatic toxicity of isradipine.
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One patient had MRI T2 abnormalities compatible with cyclosporin neurotoxicity.
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Acute generalized exanthematous pustulosis induced by nimesulide.
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Several patients successfully treated with halofantrine without any treatment failure have also been documented in Japan.
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Three of these patients had convulsions attributed to imipenem/cilastatin; 3.6% of the patients had seizure, or 2% of imipenem/cilastatin administrations was followed by a seizure attack.
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This patient did not initially receive surgical debridement and systemic antibiotics, the standard treatment for necrotizing fasciitis of bacterial origin.
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The diagnosis was confirmed by immunofluorescent studies.
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He received systemic chemotherapy twice and in both instances developed disseminated intravascular coagulopathy (DIC), accompanied by acute decrements of the peripheral platelet count and plasma fibrinogen, an increment of the fibrin degradation products (FDP), and bleeding tendency with the appearance of skin purpura.
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These symptoms resolved but recurred rapidly (within 24 h) and were more debilitating following a second exposure to the same antibiotics at the same doses 8 months later when the patient was readmitted for treatment of another cystic fibrosis-related pulmonary exacerbation.
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Incomplete posterior hyaloid detachment after intravitreal pegaptanib injection in diabetic macular edema.
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The conglomerate of plastic threads, entrapped food material and other debris, formed a huge mass occupying the whole stomach.
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Bronchoscopy revealed diffuse erythema without bleeding.
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Nonsteroidal antiinflammatory drugs can cause oral ulcers.
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The case of a patient with apparent cocaine toxicity and drug-mediated hypertension and tachycardia is presented.
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As a possible mechanism, a competitive inhibition at the receptor site of female hormones involved in water regulation is suspected.
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The male patient was treated with 225-mg/day clozapine and the time to the diagnosis of agranulocytosis was 6 weeks.
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Vortex keratopathy associated with atovaquone.
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After several unrevealing medical work-ups, he was found to have a high blood lead level (122 microg/dL); he has a history of scraping and sanding lead paint without adequate protective measures.
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A case of systemic lupus erythematosus complicated by pure red cell aplasia and idiopathic portal hypertension after thymectomy.
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No subjective discomfort was reported.
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Ultrasound-guided block may improve patient safety by avoiding the soft tissue structures in the needle path that can't be readily seen by fluoroscopy.
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Rhabdomyolysis following clarithromycin monotherapy.
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Rifampin (RFP) increases hepatic microsomal enzyme activity, and there are case reports of RFP-induced hypothyroidism, all associated with Hashimoto's thyroiditis.
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Without other causes for the hyponatremia, she was diagnosed with the syndrome of inappropriate antidiuretic hormone, presumably caused by desmopressin.
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Immunohistological studies showed that these cells were positive for CD30 and CD79a, but not for CD15 or CD20.
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Hypertension was found to be the most significant risk factor for developing retinopathy.
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Both patients were then treated with a carboplatin alternative to cisplatin in the following courses, which resulted in neither a relapse of the colitis nor a recurrence of the malignancies up to this time.
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In conclusion, this case strongly suggests that gliclazide can induce acute icteric liver necro-inflammation which may be misdiagnosed clinically as acute viral hepatitis.
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CONCLUSION: To the best of our knowledge, this is the first time colchicine intoxication in this age group has been described in the English literature.
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Choline magnesium trisalicylate was discontinued after eight days and the patient's LFT quickly returned to normal.
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Neuroleptic malignant syndrome and lithium carbonate.
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Two weeks later the patient presented with acute oliguric renal failure, symptomatic hyperkalemia and metabolic acidosis, necessitating emergency dialytic treatment.
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Two anephric patients in the course of one year erythropoietin therapy improved their anemic status without changes in Mean Arterial Blood Pressure.
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Localized dyskeratotic plaque with milia associated with sorafenib.
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5-fluorouracil (5-FU)-associated peripheral neuropathy is an uncommon event.
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Bradycardia and congestive heart failure associated with ocular timolol maleate.
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CASE REPORT: A 29-year-old black man, HIV-infected since 1996, began highly active antiretroviral therapy (HAART) with zidovudine, lamivudine, and indinavir.
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RESULTS: One day and three days after an uneventful intravitreal injection both patients experienced structured hallucinations including trees, faces, and water for approximately 15 to 30 minutes.
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Gelatinous transformation of bone marrow following chemotherapy for myeloma.
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Serious maternal bradycardia and asystole in laboring parturients after combined spinal-epidural labor analgesia are rare.
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Low-dose methotrexate was added to their treatment regimens and led to significant improvement or clearing with a favorable side-effect profile.
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Because etoposide-induced pulmonary toxicity is an uncommon but serious adverse event, clinicians must be vigilant about the possibility of it, so that the optimal treatment can start as soon as possible.
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A preclinical study in rats treated with TKI showed a statistically significant increase in benign and malignant renal tumours.
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The patient presented with a decrease in visual acuity and pain 2 days after the procedure.
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In each case, renal dysfunction and BK viral load progressed despite reduced immunosuppression, and persistent BK virus infection was documented in serial renal allograft biopsy specimens.
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Cannulation of the radial artery can result in complications ranging from arterial thrombosis, arterial aneurysm, compartment syndrome, infection, nerve injury and skin necrosis to possible thumb or even hand necrosis if not recognized and treated early.
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This is a clinical presentation of a 14-year-old female who had weight loss and vomiting following spinal fusion surgery.
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On day 3 he was admitted and his electrocardiogram demonstrated sinus arrest with junctional escape rhythm with a rate of 42 min(-1).
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The day after methotrexate administration, the patient complained of severe back pain and urinary retention.
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We report a case of recurrent torsades de pointes following treatment with pentavalent antimonial drugs and amiodarone.
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Epoprostenol (prostacyclin) is currently approved for treatment of primary pulmonary hypertension; however, it is being evaluated in other forms of pulmonary hypertension, particularly scleroderma.
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Spontaneous splenic infarction associated with sumatriptan use.
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Unexplained menorrhagia and hematuria occurred in a 13-year-old female with a mild inherited platelet disorder who had never experienced prior bleeding as a result of this disorder.
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Progressive anemia following combination therapy with interferon-alpha and interleukin-2 in a patient with metastatic renal cell carcinoma.
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Coronary artery spasm usually responds to sublingual nitroglycerin.
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We present the case of a female with DDST, who responded to aripiprazole-mirtazapine combination, a finding that is in accordance with the initial approach of this disorder as a part of the schizophrenic spectrum, but also supports the hypothesis of serotonin dysfunction in DDST.
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The postoperative histological diagnosis was endometrioid adenocarcinoma in an endometriotic cyst with a gradual transition of the degree of cellular atypia noted from typical endometriotic epithelium, to atypical endometriosis, and finally to adenocarcinoma.
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Two patients with osteomyelitis who developed reversible cholestatic jaundice during treatment with oxacillin derivatives are described.
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The possibility that the underlying disease or other chemotherapeutic agents may increase the risk of pulmonary toxicity can, however, be discussed.
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Total excision of the lesions with concomitant four-combined antituberculous therapy proved successful.
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The daily carboplatin dose was calculated based on the Calvert formula, using a target area under the plasma concentration-time curve (AUC) value of 3.25 mg.min/ml and applying the Cockcroft-Gault equation to estimate the glomerular filtration rate.
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To the best of our knowledge, this patient is the youngest, and only the fourth person in the English-language literature to develop colonic carcinoma after combination chemotherapy of Hodgkin's disease without radiation.
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Probabilistic analysis of decision trees using symbolic algebra.
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Advantages of treatment of hypertension with Minoxidil.
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CONCLUSIONS: We reported the association of multiple sclerosis and intracranial meningioma and observed the progression of the meningiomas during interferon treatment.
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PURPOSE: Platinum-based therapy is the cornerstone of ovarian cancer treatment.
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Fever, pulmonary infiltrates, and pleural effusion following acyclovir therapy for herpes zoster ophthalmicus.
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In reviewing the literature, the authors discuss the currently available therapies for such infections of the spine, and highlight the growing incidence these and other formerly rare infections.
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Eosinophilic peritonitis responding to treatment with glycyrrhizin.
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Thus, the patient's clinical course and workup strongly support a diagnosis of lenalidomide-induced hypersensitivity pneumonitis-like syndrome.
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We report two new cases of sarcoidosis in two patients with hepatitis C virus infection treated with interferon alfa and ribavirin.
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The mechanism of the reaction and guidelines for subsequent use of cyclosporine are not well defined.
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Further studies are needed to evaluate the pathogenesis of cystoid macular edema and determine whether vascular endothelial growth factor blockade should be included in treatment modalities for this condition.
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Monoclonal gammopathy and subsequent multiple myeloma in a patient on chronic diphenylhydantoin therapy.
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Therefore, we believe that screening for HBsAg is insufficient for detecting latent HBV carriers, and that investigation for hepatitis B core antibody (HBcAb) is essential.
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The probable proarrhythmic action of amiodarone, although rare, is reviewed along with a discussion of the novel use of intravenous magnesium sulfate therapy.
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All three patients had clinical courses characteristic of RS and two had supportive histologic findings on liver biopsy.
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Diagnosis of transfusion-associated graft-versus-host disease by polymerase chain reaction in fludarabine-treated B-chronic lymphocytic leukaemia.
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The possibility of phenytoin hypersensitivity reactions should be considered when patients receiving phenytoin have unusual symptoms, particularly fever, rash, and lymphadenopathy.
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