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Studies of porphyrin metabolism in patients treated with cyclophosphamide may help to elucidate this possibility.
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The resultant renal failure and fluid overload necessitated peritoneal dialysis.
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Unexplained menorrhagia and hematuria: a case report of Munchausen's syndrome by proxy.
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Examination of bone marrow at the last clinical follow up demonstrated both acute myeloid leukemia and residual metastatic Ewing sarcoma.
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Alteration in carbohydrate metabolism, such as transient glucose intolerance at the start of therapy in non-diabetic acromegalic patients, and increased sensitivity to insulin or oral hypoglycemic agents in diabetic acromegalic patients, is common.
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Rapid improvement of delusional depression following drug-induced seizures: case report.
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These findings did not correlate with changes in serum IgG, IgA, IgM, IgD, IgE or alpha 2-macroglobulin.
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Rapid onset of muscle weakness (rhabdomyolysis) associated with the combined use of simvastatin and colchicine.
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PURPOSE: The case of a patient who developed aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension simultaneously during treatment with trimethoprim-sulfamethoxazole is described.
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RESULTS: We measured the highest acyclovir serum levels reported so far (229.9 mumol/L = 51.8 mg/L).
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His fever resolved and clearance of the nodule was documented on a CT scan 2 months after diagnosis and initiation of treatment.
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Transient cardiac arrhythmias related to lopinavir/ritonavir in two patients with HIV infection.
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When fentanyl was subsequently administered to treat her pain, the stridor resolved.
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RESULTS: Scouting biopsies demonstrated multiple comedones and ruptured epidermoid cysts.
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The number of melanosomes, mitochondria, endoplasmic reticulum and dendrites were increased.
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Sudden sensorineural hearing loss has rarely been reported as a result of NSAID use.
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We describe a patient in whom this interaction caused a series of dangerous clinical events.
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In two cases acute renal failure also occurred.
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Here we report our experience with three of these patients, who experienced progressive disease after a variety of previous therapies, including prior immunotherapies, and who achieved good outcomes with ipilimumab.
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Gold nephropathy due to auranofin obscured by tolmetin pseudoproteinuria.
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Autoimmune hemolytic anemia associated with postirradiation malignant stromal tumor (leiomyosarcoma) of the jejunum.
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Three (10%) eyes had an epithelial defect, nine (31%) had iridocyclitis, and seven (24%) had associated secondary glaucoma.
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Two underwent shunt revision for proximal obstruction, with an intact distal system.
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A 32 year old man with chronic severe asthma, requiring maintenance oral corticosteroids, was started on a weekly dose of methotrexate.
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In contrast, the LMW heparinoid Org 10172 (Organon, Oss, The Netherlands) did not cause platelet activation.
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However, a Jarisch-Herxheimer reaction occurring in a patient receiving treatment for ocular syphilis can be serious, resulting in the rapid loss of vision.
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This report describes the development of multiple-site, biopsy-proven osteonecrosis in a patient with small-cell bronchogenic carcinoma who had received chemotherapy and short-term administration of corticosteroid.
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Pathological features such as large amounts of lipid droplets and lysosome-melanosome complexes were also found within the melanocytes.
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Prompt diagnosis and surgery offer excellent chances of surviving this fatal condition.
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She received an accidental 450-mg bolus injection of morphine intrathecally and developed hypertension, status epilepticus, intracerebral hemorrhage, and respiratory failure.
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The prevalence of TD was 3.96% (4/101).
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The withdrawal of PI was followed by a complete improvement of renal function.
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This report emphasises the clinicopathological features and the diagnostic peculiarities of the acute tumour lysis syndrome, which occurs uncommonly in dogs.
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Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) is a primary lymphoproliferative T-cell disorder, currently classified as a peripheral T-cell non-Hodgkin's lymphoma.
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This appears to cause immediate regression of the neovascular frond and allows time for the laser, which is applied subsequently to have its effect.
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Acute renal failure during lisinopril and losartan therapy for proteinuria.
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An increase in exercise capacity was reported by 78% of patients; objective measurements showed that the mean value of VO2max in a subgroup of 11 patients increased by 50% after treatment.
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Symptoms correlated with an increase in alkaline phosphatase and with bone scintigraphy findings.
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INH, which is a leading cause of drug eruptions in the above group of drugs was withdrawn.
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Growth hormone deficiency (GHD) results in salt and water depletion and studies confirm that replacement leads to sodium and vasopressin-mediated water retention in patients with intact posterior pituitary function.
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A biopsy specimen showed pleural and parenchymal fibrosis.
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Magnetic resonance imaging showed several areas of abnormally high signal on T2-weighted images in the brainstem, thalamus, and mamillary bodies.
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Drug-induced mammary hyperplasias have been reported as rare complications of D-penicillamine and Neothetazone.
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Both 6-MP and AZA are widely used and are known to cause hepatotoxicity in a proportion of patients.
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Patients with metastatic breast adenocarcinoma showed complete responses in both treated nodules after ECT.
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He developed a late secondary infection in some sites treated with imiquimod.
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Foscarnet resistance and cidofovir resistance have also been described, but no previous reports have suggested treatment regimens for patients with CMV refractory to all three of these drugs.
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However, it is still produced and marketed in several countries in Central and South America as well as in Europe, Asia, and Africa.
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Thereafter, the patient's renal function slowly worsened and she started chronic hemodialysis 5 years later.
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Physical findings and urine output were normal, except for increasing blood urea nitrogen (BUN), serum creatinine and mild proteinuria.
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Our observation would confirm this statement.
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Our second patient had a 2-year history of asthma prior to the onset of rippling muscles which preceded the myasthenic symptoms by 4-8 weeks.
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The patient suffered no side effects, and use of G-CSF represents an important addition to the management of a life-threatening drug reaction.
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Anaphylaxis from isoniazid is a possible side effect to this commonly prescribed antibiotic.
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If a strong clinical likelihood of local disseminated intravascular coagulation exists, then In-111 platelets may be valuable in localizing the focus of platelet consumption.
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However, spontaneous degenerative rupture of the plantar fascia is not well documented in the literature.
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Phantom limb pain as a manifestation of paclitaxel neurotoxicity.
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Knowledge regarding potential adverse effects of CAP is paramount and dose modification is indicated with development of neurotoxicity.
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One patient has a resistance-related mutation (M460I); the major risk factor for emergence of resistance in this patient was the presence of early and persistent antigenaemia.
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The nephrotic syndrome was treated successfully with prednisolone.
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New therapeutic approaches should be explored.
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It is suggested that special precautionary measures should be taken regarding the dose and the route while administering epinephrine to avoid mishaps.
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L. monocytogenes infection should therefore be considered in CAPD patients with gram-positive rod peritonitis, even if immunocompetence is presumed.
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Occult quinine-induced thrombocytopenia.
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The importance of high-tone audiometry in monitoring for ototoxicity.
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In rare cases mitomycin C (MMC) may induce cancer-associated hemolytic uremic syndrome, which is characterized by hemolytic anemia, thrombocytopenia and progressive renal failure.
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Given that discontinuation of nitrofurantoin and introduction of methylprednisolon therapy significantly lowered liver enzyme levels, restoring most of them to normal, we concluded that this was probably the case of toxic liver damage caused by nitrofurantoin.
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We describe a 51-year-old woman with sacroiliitis following a fall.
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Fluorescent in situ hybridization confirmed donor cells at sites of peribronchiolar inflammation.
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Lymph node biopsy showed almost complete effacement of the nodal architecture with diffuse proliferation of small vessels forming an arborizing network, surrounded by atypical lymphocytes, usually CD3+ CD4+ and occasionally CD3+ CD8+.
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We report a protocol in which anticonvulsant agents are discontinued before discharge from our neonatal unit.
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Successful treatment of refractory immune hemolysis following unrelated cord blood transplant with Campath-1H.
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A 59-year-old female was admitted to Tsukuba University Hospital and diagnosed as IgA-lambda multiple myeloma (stage IIIA).
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Coincident with the preeclampsia was a postdural puncture headache complicating the diagnosis of late postpartum preeclampsia.
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OBJECTIVE: To propose a new hypothesis regarding the possible role of glucocorticoid excess in patients with an extended acute illness, based on a patient's presentation and therapy in a critical care situation.
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Prazosin-induced first-dose phenomenon possibly associated with hemorrhagic stroke: a report of three cases.
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Moreover, applying the Cockcroft-Gault equation to obese patients leads to an overprediction of creatinine clearance and, when used in the Calvert equation, consequently to a carboplatin dose that is too high.
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Therapy with IFN-alpha may be associated with a number of neuropsychiatric symptoms, such as Parkinsonism, akathisia, seizure, and depressive disorders.
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The patient has received follow-up treatment for three years and five months without local or systemic effects observed.
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All 3 had documented CBZ blood levels in the therapeutic range at the time, and none had other symptoms or signs of clinical intoxication.
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Drug-induced hypersensitivity syndrome associated with a marked increase in anti-paramyxovirus antibody titers in a scleroderma patient.
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Early overanticoagulation with acenocoumarol due to a genetic polymorphism of cytochrome P450 CYP2C9.
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Although the development of posterior subcapsular cataracts is a known complication of systemic steroid therapy, it usually occurs after several years of chronic administration.
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Here we present the case of a generalized lichen nitidus with involvement of the palms in a patient with hepatitis C after systemic treatment with interferon alpha and ribavirin.
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He developed fever, nausea, diarrhea, and malaise and stopped taking on the third day after commencing Pentasa.
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The use of adenosine has been suggested as a diagnostic tool in the evaluation of wide ORS complex tachycardia.
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CASE SUMMARY: A 72-year-old white woman was treated with sertraline for depression for 18 months and was then admitted to the hospital with a fractured tibia.
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Three of the patients had the carcinoid syndrome and one a renal carcinoma, and all were treated with interferon-alpha 2b or 2a (IFN-alpha 2b, 2a) with doses ranging from 1.5 x 10(6) U daily to 18 x 10(6) U three times weekly.
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Nephrogenic diabetes insipidus and renal tubular acidosis secondary to foscarnet therapy.
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On day 4, following 3 doses of dalteparin, the patient developed acute respiratory distress attributable to a massive right hemothorax confirmed by computed tomography pulmonary angiography (CTPA) and intercostal drainage of 1500 mL of frank blood.
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An extensive MEDLINE search located 22 other reports of patients who developed HDAs, sometimes associated with thrombosis, but whose platelet counts did not decrease.
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A liver biopsy revealed chronic hepatitis with bridging fibrosis and piecemeal necrosis.
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One of the patients presented hyperprolactinemia and a raised estrogen/androgen ratio but the hormone levels were not raised in the other.
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On the first occasion she experienced arterial fibrillation secondary to a severe episode of hypotension following local anaesthesia, while on a course of beta-blockers.
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These organisms have occasionally been reported as a cause of serious infections in man but have not been reported as a cause of shunt infection.
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Three prepubertal children who suffered severe, incapacitating anxiety disorders with panic-like symptoms were treated successfully with clonazepam.
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Post-transplant lymphoproliferative disorder (PTLD) is a life-threatening complication after lung transplantation, for which several risk factors including pretransplant seronegativity for Epstein-Barr virus are known.
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We present this report to alert physicians and pharmacists about the potential risk of the first-dose phenomenon even at the recommended initial doses of prazosin in hypertensive patients who have suffered a recent stroke.
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A review of the literature disclosed 8 cases of this association with a fatal fulminant outcome in 5 cases.
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Expandable metallic stents have been used effectively to treat multiple nonsurgical esophageal conditions.
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