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Because the combination of bleomycin and vinca alkaloids is commonly used for the treatment of AIDS-related Kaposi's sarcoma, clinicians should be aware of the risk of provoking acral necrosis in patients who develop Raynaud's phenomenon under chemotherapy.
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Early discontinuation of anticonvulsants after neonatal seizures: a preliminary report.
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To our knowledge, this is the second such case reported, as Merkel cell carcinoma most commonly occurs after kidney and heart transplants.
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This report describes the management of repetitive paroxysms of supraventricular tachyarrhythmias triggered by catheter manipulation during interventional procedures in two children.
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OBJECTIVE: The purpose of the study is to investigate the relationship between inhaled or intranasal adrenergic agonists and corticosteroids and the development of central serous chorioretinopathy (CSC).
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We thus concluded that an excessive dose of AZ had probably destroyed the gastric mucosal barrier or thrombocytopenia due to bone marrow disorder and thus eventually led to the development of hemorrhagic gastritis.
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The American Society for Regional Anesthesia and Pain Medicine has specific guidelines for treatment of these patients when they undergo neuraxial anesthetic procedures.
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True allergy to mercury is rare but is more common in females.
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This delivery system, however, carries with it an intrinsic morbidity warranting attention in the often prolonged chemotherapy regimens demanded by cancer patients.
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Extensive visual loss with topical facial steroids.
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In addition, IVIG may effectively modulate the overreactive immune system in AHS.
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She admitted that she often induced the episode herself and derived pleasure out of it.
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The first therapeutic schedule included rifampicin, isoniazid and ethambutol; no uniform treatment could be used for these patients.
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It was not accompanied by clinical hallmarks of hypersensitivity, which is suggestive for metabolic rather than for immunoallergic idiosyncrasy.
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All patients had taken phenytoin for variable time periods (range 16-80 days; mean: 40) and were on the medication when the skin lesions first appeared.
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Both analyses confirmed that the isolated material is calcium carbonate.
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Parenterally administered biperiden proved to be highly effective in the control of the symptoms.
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We conclude that the use of hemopoietic colony stimulating factors might be a suitable means to achieve the correction of severe thionamide-induced hematologic adverse reactions.
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The patient also developed red cell alloantibodies that produced a delayed hemolytic transfusion reaction (DHTR) and broad HLA antibodies.
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METHODS: Each patient received a 10 unit/m2 dose of bleomycin administered intravenously at 1 to 1.5 units/minute.
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Monocytic leukemoid reaction, glucocorticoid therapy, and myelodysplastic syndrome.
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A 44-year-old woman is described in whom amiodarone, disopyramide, and quinidine, administered alone separately, induced atypical ventricular tachycardia (AVT, torsade de pointes).
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Rifampin (RFP) increases hepatic microsomal enzyme activity, and there are case reports of RFP-induced hypothyroidism, all associated with Hashimoto's thyroiditis.
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Rapamycin/sirolimus (SR), trade named Rapammune (Wyeth-Ayerst, Sydney, Australia), is a potent immunosuppressive drug associated with myelosuppression, hypertension, hyperlipidemia, and infection.
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More recently, extrapyramidal side effects have gained importance because they are significant factors in both the patient's acceptance of the particular drug and his or her social adjustment.
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Tacrolimus (FK506), an immunosuppressant, has been associated with mutism in adults after liver transplant.
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The striking temporal relationship between commencing dalteparin on day 1 and subsequent development of effusion on day 4, following 3 doses of LMWH, led us to believe that the bleed occurred as a result of the therapy.
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ENT surgeons, general physicians, and infertility experts should consider this in the differential diagnosis of neck swellings, particularly after OHSS and IVF treatment, and in this case report, we emphasis the need for an urgent ultrasound of the neck in such patients.
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Zonisamide is a broad-spectrum antiepileptic drug used to treat various types of seizures.
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Discontinuation of the Osmolite resulted in a prompt prolongation of the prothrombin time.
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Additional history disclosed that the patient had been given metamizole for pain before onset of his illness.
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Liver biopsy showed cholestasis with both cytological and architectural alterations of interlobular bile ducts.
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CASE: We present an 11-year old male with Budd-Chiari syndrome who experienced profound worsening of chronic aphthous ulcers after immunosuppressive therapy was changed from tacrolimus to sirolimus.
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Reversal of post-reperfusion coagulopathy by protamine sulphate in orthotopic liver transplantation.
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INTRODUCTION: We describe the neurointensive care (NIC) management of a patient with severe cerebral swelling and raised intracranial pressure (ICP) after severe sodium valproic acid (VPA) intoxication.
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Quetiapine and obsessive-compulsive symptoms (OCS): case report and review of atypical antipsychotic-induced OCS.
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Thiabendazole is a relatively safe and effective agent with a wide range of activity against nematodes infesting the gastrointestinal tract.
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This is an unusual association, and to date only seven cases have been reported.
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OBJECTIVES: The authors described a case of Hashimoto's disease during interferon-alpha (IFN-alpha) treatment for chronic viral C hepatitis in a patient with the specific genetic susceptibility associated with the thyroid disease.
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Cidofovir is an antiviral agent that demonstrates in vitro activity against murine polyomavirus and has been proposed for treatment of BKVN in renal allograft recipients.
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Pulmonary sarcoidosis following interferon therapy for advanced renal cell carcinoma.
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Amphojeloma: antacid impaction in a critically ill patient.
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Most of these cases have been associated with the administration of chemotherapy or radiotherapy for CLL, suggesting that the former may be a secondary leukemia.
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Therefore, although garenoxacin reportedly causes fewer adverse reactions for cardiac rhythms than third-generation quinolone antibiotics, one must be cautious of the interference of other drugs during hypokalemia in order to prevent TdP.
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This case reminds physicians of the importance of drug reactions, their severity, techniques for diagnosis and methods of management.
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A 45-year-old man presented with deep vein thrombosis of the right leg and bilateral pulmonary embolism.
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Lansoprazole was discontinued, and the platelet count returned to normal.
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Cerebral air embolism after intrathoracic anti-cancer drug administration.
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Zolpidem (Ambien), a relatively new nonbenzodiazepine sedative-hypnotic, was involved in the death of a 39-year-old obese male who was being treated for depression and insomnia.
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Successful treatment of aortic thrombosis after umbilical catheterization with tissue plasminogen activator.
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Initial treatment including removal of the catheter and antibiotic therapy was unsuccessful and both patients had persistent fever and bacteremia.
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Death ensued after three days due to cerebral edema with herniation.
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CONCLUSION: We review the literature of reported cases of primary osteogenic sarcomas of the skull to discuss the common clinical presentation, evaluation methods, and recommended treatment plans.
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In the present study, our cases suggested that patients receiving a high dose of co-trimoxazole should be evaluated for these potential complications during a course of treatment, particularly in elderly patients with preexisting renal dysfunction.
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These cases were compared with those attributed to anthracyclines and taxanes.
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The patient presented unfavorable evolution with progressive worsening of respiratory function, hypotension, and renal failure.
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Some patients received antilymphocyte globulin (OKT3), when acute rejection was imminent.
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The aim of our paper was to describe hepatotoxicity of sirolimus (SRL) in a kidney graft recipient.
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6. The wide variety of drugs associated with this complication suggests that any cytotoxic agent may be leukemogenic.
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An acute viral illness or reactivation of systemic lupus erythematosus were the suspected diagnoses.
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The patient's second acceleration occurred 22 months after the CML diagnosis.
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A female patient with HER2 positive, metastatic breast cancer presented with pulmonary infiltrates, and a plural effusion dyspnoea after several months of trastuzumab treatment.
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Acute chest pain is a common presentation in emergency.
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Differences in interpretation by patients and healthcare professionals may cause the observed disparities in seriousness and outcome of reported ADRs.
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CONCLUSIONS: Topical imiquimod 5% cream seems to be a useful treatment for eyelid nodular basal cell carcinoma in selected cases, but further long-term studies are needed to assess the efficacy and safety of this approach.
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The patient received hyperbaric oxygen therapy for 1 week.
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The most commonly cited cause of drug-induced IHA has been receipt of second and third generation cephalosporin antibiotics.
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Syncytial giant cell hepatitis recurred after transplantation and was efficiently treated with ribavirin.
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Antibiotic-associated colitis (pseudomembranous colitis) developed in four patients with spinal cord injury and taking oral trimethoprim-sulfamethoxazole.
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It has been shown to possess beneficial effects in reducing the relapse rate in relapsing-remitting multiple sclerosis.
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Blood, urine, and sputum cultures were positive for Trichosporon.
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Valproate embryopathy in three sets of siblings: further proof of hereditary susceptibility.
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Acute pancreatitis in a child with idiopathic ulcerative colitis on long-term 5-aminosalicylic acid therapy.
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METHODS: An extensive review of the English medical literature through the National Library of Medicine (PUBMED) was performed to identify patients who had received or continued to receive radiation therapy while on phenytoin.
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A variety of movement disorders are known to occur in association with carbamazepine (CBZ) therapy in adults and children, but development of tics has been described infrequently and only in patients with underlying Tourette's syndrome or other movement disorders.
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Among 12 thyrotoxic patients, a patient with arrhythmogenic right ventricular dysplasia, who had been taking amiodarone for 4 years, developed thyrotoxicosis with subacute onset, accompanied by transiently positive thyrotropin (TSH) receptor antibody (TRAb), or thyrotropin-binding inhibiting immunoglobulin (TBII).
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We describe a 28-year-old man who was brought to the emergency department with a new-onset seizure and clinical signs and symptoms consistent with advanced delirium tremens.
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A T9-10 epidural catheter was placed prior to induction of general anaesthesia.
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Calciphylaxis (calcific uremic arteriolopathy) is a severe complication of hemodialysis characterized by subcutaneous calcification of the small arteries and tissue necrosis.
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Investigations did not reveal associated infection or an underlying immunological disorder; however, the patient admitted to excessive use of topical anesthetic eyedrops in the post-LASEK period.
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In one patient, disease was confined to the colon, while three patients had disease involving the terminal ileum and colon.
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Visual loss after a single small dose of vincristine has never been reported.
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Four cats had a history of difficulty in regulating the diabetic state.
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Motor cortex excitability was studied by single and paired TMS and MEPs were recorded from FDI.
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After intravitreal injection of triamcinolone acetonide, cataract may rapidly develop in eyes that have been intensively treated, topically and systemically, by corticosteroids for several years.
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The reported cases of in utero exposure to cyclosposphamide shared the following manifestations with our patient: growth deficiency, developmental delay, craniosynostosis, blepharophimosis, flat nasal bridge, abnormal ears, and distal limb defects including hypoplastic thumbs and oligodactyly.
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Survival of patients with AL amyloidosis is no more than 1 to 2 years from the time of diagnosis with current management approaches.
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Although immunosuppressive medications were rapidly tapered, neither patient could receive potentially curative therapy with unmanipulated donor-derived lymphocyte infusions (DLI) because of the substantial risk of severe GVHD.
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In this article, four patient reports of a specific interaction--the serotonin syndrome--are presented.
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These patients may develop systemic sepsis through bacterial or fungal translocation across the intestinal wall.
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We examined and treated six patients with acanthamoeba keratitis associated with contact lens wear from 1981 to 1988.
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Heparin was given for 15 hours after stenting, and aspirin and ticlopidine medication were continued.
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It is mainly adolescents who are experimenting with these plants.
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Isotretinoin, a drug used for the treatment of acne, has been shown to have teratogenic effects.
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Physical examination showed proximal muscle weakness in his arms and legs.
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CASE SUMMARY: A 57-year-old female suffered from osteomyelitis of the left humerus, with a white blood cell (WBC) count of 2.8 x 10(3)/mm3 and absolute neutrophil count (ANC) of 0.28 x 10(3)/mm3, occurring after 24 days of vancomycin therapy.
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Following administration of 0.1 mmol/kg of gadodiamide to a patient with end-stage renal disease, the serum clearance of this contrast agent by automated PD was examined.
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METHODS: A retrospective study in an institutional practice.
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Brain computed tomography disclosed bilateral temporal hypodensity with edema.
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OBJECTIVE: To discuss the various diagnostic and treatment options that should be considered when managing parotid duct injuries that result from skin cancer extirpation.
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