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Within 24 h after the first injection to her left arm, the patient developed pruritus and erythematous papules at the injection site and painful papules on her hands.
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Abemayor).
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Use of alpha-agonists for management of anaphylaxis occurring under anaesthesia: case studies and review.
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This article describes the interval appearance of malignant, linear-branching, microcalcifications during neoadjuvant chemotherapy for locally advanced breast cancer.
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We report a case of a women in whom a malignant mixed mesodermal tumor was diagnosed while she was taking raloxifene, which is also a selective estrogen receptor modulator.
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OBJECTIVE: To describe a patient with asymptomatic bronchial asthma and hypertension who developed an acute asthma attack after receiving sustained-release verapamil.
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Gallstones and bile sludge are common side effects of octreotide therapy but rarely become symptomatic or require treatment.
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PARTICIPANTS: Five eyes in four patients who underwent LASIK in different locations around the world and had culture-positive mycobacterium keratitis develop.
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After discontinuing captopril and starting systemic steroids, her symptomatology rapidly improved, and her eosinophilia and radiographic abnormalities both resolved.
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Oral antiviral and topical steroids in tapered dosages were administered.
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Particular attention should be paid to tiny skull lesions and to key events preceding the pain.
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Electrodiagnostic studies at variable points during the disease course showed signs of acquired demyelination consistent with CIDP.
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Our case re-emphasizes the need for investigation of factors precipitating ARF in children with idiopathic NS.
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Eight days after the end of interferon treatment, he showed signs of inability to sit still for ten seconds and walked around constantly.
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A possible role for a factor with thrombosis-inducing activity (TIA).
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A 43-year-old woman with multiple sclerosis (MS) had nephrotic syndrome 21 months after starting treatment with interferon (IFN)-beta-1b (subcutaneous administration).
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We report one case of pregnancy-onset severe diffuse proliferative nephritis in a patient with systemic lupus erythematosus (SLE), who was successfully treated with a combination of anti-tumour necrosis factor (TNF)-alpha, plasmapheresis and high-dose intravenous gammaglobulin.
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The reported cases of in utero exposure to cyclosposphamide shared the following manifestations with our patient: growth deficiency, developmental delay, craniosynostosis, blepharophimosis, flat nasal bridge, abnormal ears, and distal limb defects including hypoplastic thumbs and oligodactyly.
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The intense stimulation of B lymphocytes and decreased T lymphocyte activity in asbestos-exposed populations may result in development of B-cell malignancies.
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Three additional cases have also been observed.
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Subclinical entrapment may thus be an important factor leading to vulnerability of nerves in lead neuropathy.
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Reduction in the dose of olanzapine was followed by normalization of the white blood count which allowed continuation of the medication.
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Cidofovir is an antiviral agent that has been proposed for treatment of BKVN.
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Markedly increased pigmementation of skin immediately overlying veins used for multiple 5-fluorouracil infusions was noted.
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Two patients treated with 5-fluorouracil (5-FU) for disseminated adenocarcinoma of the colon developed cerebellar dysfunction typical of 5-FU neurotoxicity.
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The safety of cyclo-oxygenase 2 (COX-2) preferential inhibitors such as meloxicam is debated.
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Effective treatment is available provided surgical manipulations cease.
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RESULTS: Therapy consisted of 4 cycles of paclitaxel chemotherapy.
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We concluded that the colonic ulcer and the sigmoidovesical fistula had been caused by the administration of calcium polystyrene sulfonate and sorbitol.
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Treatment of non-Hodgkin's lymphoma with the CHOP regimen consists of intravenous cyclophosphamide 750 mg/m2 (day 1), intravenous doxorubicin 50 mg/m2 (day 1), intravenous vincristine 1.4 mg/m2 (day 1), and oral prednisone 100 mg (days 1-5).
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The patient died approximately 6 months later of persistent and progressive retinoblastoma without any clinical evidence of lymphoma.
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This is the first reported case of BOOP associated with single-agent rituximab, and along with two other patients we describe, as well as two prior reports of BOOP in NHL patients receiving rituximab-based combinations, strengthens the possibility of a causal relationship.
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The toxic effects of methotrexate included elevated liver transaminases (3/4), nausea (2/4), abdominal pain (2/4), bone pain (2/4), mild neutropenia (1/4), and mild pruritus (1/4).
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A 55-year-old woman presented an episode of acute urticaria and labial angioedema 60 minutes after ingesting 500 mg of cloxacillin for a skin abscess.
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We describe a case of spontaneous muscle necrosis of the anterior tibial compartment occurring in a patient who had a hypophysectomy for a craniopharyngioma five years previously.
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Uncommonly, erythema multiforme (EM) can develop in such patients at the port site during or soon after cranial radiation and can rapidly progress to EM major.
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One patient also developed bilateral angle closure glaucoma.
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He stopped this therapy in February 1996 because of asthenia, diplopia, headache, and anxiety.
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All patients experienced severe anaemia after induction chemotherapy despite erythropoietin.
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Differential diagnosis is very important and anti-tuberculous drugs must be continued if the diagnosis is tuberculosis.
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It is our experience that a good outcome is dependent on early and specific treatment.
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We report the case of a 23-year-old woman with diffuse large-cell lymphoma who received an accidental overdose of this chemotherapeutic regimen.
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These findings, together with increased urinary copper excretion and the absence of clinical improvement, are compatible with a generalized defect in copper metabolism, transport or storage.
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Autopsy findings were consistent with bleomycin and oxygen-induced pulmonary damage.
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RESULTS: There was an immediate clinical improvement (increased alertness, improved concentration) but severe hypernatraemia developed (peak 169 mmol/l) necessitating revision of his desmopressin and fluid intake regimen.
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The complete treatment schedule required the administration of a total of 708 mg of recombinant FVIIa.
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We report a case of baclofen withdrawal syndrome resulting from oral baclofen underdosing.
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In this respect, we present two patients with hypertension and dyslipidaemia together with elevated serum uric acid levels.
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Eyes from two individuals examined at autopsy showed significant changes.
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Metabolic balance studies and rechallenge with hydrochlorothiazide were undertaken to investigate the mechanism of the thiazide-induced hyponatremia.
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Renal failure associated with the use of dextran-40.
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We should also bear in mind that BMD scores alone are not indicative of fracture risk, and other tools such as the WHO-FRAX (Fracture risk assessment tool), serum vitamin D3 levels and bone turnover markers should be used where appropriate.
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Histological examination revealed hyphae and arthrospores in the hair follicles and in the dermis with a diffuse dermal infiltrate consisting of lymphoplasmacytic cells, and focal collections of epithelioid cells, neutrophils and mild interstitial edema.
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Common causes of residual limb pain and the pharmacology of capsaicin cream are discussed.
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CONCLUSIONS: We report this case of the concomitant appearance of multiple skin cancers and nail changes associated with hydroxyurea use.
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Reversible sirolimus-associated pneumonitis after heart transplantation.
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We report a patient who developed spontaneous splenic infarction after the use of sumatriptan for the treatment of migraine headache.
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While undergoing treatment with albendazole, he developed worsening diarrhea with abdominal pain and fever.
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CASE SUMMARY: An 89-year-old man was admitted for dementia with behavioral disturbance and psychosis and was started on olanzapine 2.5 mg twice daily.
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The mean CYP2D6 activity is lower in Oriental than in Caucasian populations, because of a frequent mutation causing decreased enzyme activity.
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The ninth patient stopped taking the preparation immediately because of swollen nasal mucosae.
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We describe an infant with minimal exposure to oxygen who developed AP-ROP that led to bilateral retinal detachments and a poor visual outcome, despite following current recommended screening guidelines.
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We report a 30-year-old African-American woman with a contiguous diagnosis of breast cancer and paraneoplastic SSc.
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The authors describe pericardial hemorrhage, which is related to the use of low-dose acetylsalicylic acid in a patient with essential thrombocythemia.
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RESULTS: Three patients who developed symptoms of inflammatory bowel disease (IBD) during rofecoxib exposure are described along with pathology findings.
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BACKGROUND: Antidepressants can sometimes cause agitation, particularly in patients with bipolar disorder, but concern about such effects is generally limited to the first weeks and months of treatment.
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We report its successful use in the treatment of a nodular basal cell carcinoma.
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Adverse reactions to reserpine were reported in 26 patients (11.3 per cent), but only three of these reactions were considered life-threatening and no deaths were attributed to the drug.
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Systemic allergic contact dermatitis to 8-methoxypsoralen (8-MOP).
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The remaining clinical scenarios included intravenous catheter sepsis and factitious disorders.
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Superior sagittal sinus thrombosis was demonstrated by cerebral angiogram.
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The use of fresh frozen plasma and/or danazol before treatment prevents angioedema attacks.
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The aim of this study was to describe the occurrence of acute coronary syndromes in 3 cases of rituximab infusions.
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However, because ADPKD is a bilateral disorder, ACE-inhibitor therapy may worsen renal function, as occurs in patients with bilateral renal artery stenosis.
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The reported cases of in utero exposure to cyclosposphamide shared the following manifestations with our patient: growth deficiency, developmental delay, craniosynostosis, blepharophimosis, flat nasal bridge, abnormal ears, and distal limb defects including hypoplastic thumbs and oligodactyly.
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RESULTS: All three patients developed a biochemical-histologic pattern of cholestatic liver injury with damage to the interlobular bile ducts.
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Pulmonary thromboembolism was diagnosed, based on: (1) blood gas analysis findings of hypoxemia and (2) defective images in both of the upper lobes on urgent pulmonary blood flow scintigram.
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Thus, tacrolimus-induced HUS is a rare cause of ARF in nephrotic syndrome.
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Foreign body granuloma of activated charcoal.
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MAC infection persisted despite treatment, however, no anti-MAC drug-resistant isolates emerged throughout the clinical course in either case.
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We conclude that myocardial infarction may develop in patients treated with high-dose glucocorticoids for Graves' ophthalmopathy, and increased blood pressure may herald this complication.
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At our institution, high-dose i.v. dexmedetomidine is used to provide sedation for pediatric patients undergoing nonpainful radiological imaging studies.
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The presented patient was treated with 200 mg TCA and developed Cushing's syndrome 6 weeks later (cortisol and ACTH concentrations were below limits of detection, TCA concentrations were > 3 micrograms/l).
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Mild photophobia was the most common side effect, but could be easily overcome by wearing sunglasses.
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A 48-year-old woman who was treated for thyrotoxicosis with methimazole developed agranulocytosis.
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We report an allogeneic bone marrow transplant recipient who developed CMV infection refractory to sequential therapy with ganciclovir, foscarnet, and cidofovir.
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This analytic procedure allows an exact calculation of the statistical variance at the final decision node using automated symbolic manipulation.
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We present the case of a 20-year-old patient with Hodgkin's disease developing BOOP after chemotherapy (COPP/ABVD) and irradiation.
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Chronic nausea and morphine-6-glucuronide.
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Ultimately, this may possibly predispose a patient to increased dermatologic reactions, including TEN.
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PURPOSE: To describe the use of intravitreal bevacizumab followed by sectorial retinal photocoagulation to treat the neovascular complications of laser-induced chorioretinal anastomosis (L-CRA) for nonischaemic central retinal vein occlusion (CRVO).
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These patients appear to have experienced "spontaneous" hypertensive episodes temporally related to the ingestion of the MAOIs.
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Assuming that maintenance therapy is necessary for optimal efficacy, the issue of BCG toxicity becomes more relevant.
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Spontaneous nasal septal perforation with antiangiogenic bevacizumab therapy.
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We report the case of a lung cancer patient with bronquiloalveolar carcinoma (BAC) presenting with BOOP after chemotherapy with docetaxel and gemcitabine producing severe respiratory insufficiency, and simulating a progression of the tumor.
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Torsade de pointes during loading with amiodarone.
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The authors report on the effects of acute confusional states and deliria (pharmacogenic confusional syndromes - PCS), occurring under the influence of psychotropic drugs on the depressive syndrome of three patients.
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Emergence of cotrimoxazole- and quinolone-resistant Campylobacter infections in bone marrow transplant recipients.
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Its clinical manifestations include severe periarticular pain with inflammatory signs, especially in knees and ankles, causing functional disability.
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Another enzyme catalyzing the metabolism of antidepressants is the polymorphic S-mephenytoin hydroxylase.
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