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Native arterial thrombosis, though recognized as a severe complication of thrombin injection, has not been well described in the literature.
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Despite the significant weight loss, 4 of the 5 patients continued to take the drug due to its efficacy.
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Immune tolerance in a haemophilia A patient with high inhibitor using locally prepared lyophilized cryoprecipitate.
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Although the blood pressure remained normotensive, renal biopsy showed thrombosis of the polar arterioles and glomerular capillaries.
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BACKGROUND: There has been discussion about the acceptance of adverse drug reactions (ADRs) reported by patients to spontaneous reporting systems.
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The patient required high dose opioid to control the shoulder pain.
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In view of her cachexia and cytopaenia, emergency chemotherapy was initiated using a modified regimen of carboplatin, etoposide and vincristine (CEO) in preference to the more traditional but less well-tolerated VAC (vincristine, actinomycin D, cyclophosphamide).
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The preclinical activity profile combined with the hematological toxicity data in rodents and the water solubility of the compound compare favorably with MMC.
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Once her blood pressure stabilized, the patient improved clinically.
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RESULTS: The patient was treated with aggressive hydration, allopurinol, and repeated hemodialysis.
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They discuss this underrecognized complication of valproate use and the implications for treating elderly patients, in whom valproate use is increasing.
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Cholesterol microembolization as a sequela of oral anticoagulant therapy has been reported to cause infarction of virtually any organ, often resulting in death.
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A ventilation-perfusion lung scan showed no defects; roentgenograms showed bilateral infiltrates and a left-sided pleural effusion.
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Approximately 4% of his body surface area was involved, and he was diagnosed with PPP after skin biopsy.
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The authors describe a case of acute coronary vasospasm in a young patient undergoing thoracic laminectomy with biopsy of intramedullary tumor.
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There is evidence that corneal calcifications are correlated with chronically administered phosphate-buffered eye drops (P<0.005).
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Diagnosis and treatment of chronic postoperative bacterial endophthalmitis.
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We review the 14 previous cases published in the literature and describe two additional patients.
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Flavimonas oryzihabitans is a potential pathogen that may infect patients who have major medical illnesses, especially those who are undergoing surgery or have indwelling venous catheters in situ.
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Although the cumulative probability of acute non-lymphocytic leukemia among surviving patients at five years using life-table statistics was 7.6%, the survival curve for the 553 patients with ovarian carcinoma was only slightly affected by death from leukemia.
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A 57-year-old man developed chronic, watery diarrhea four weeks after Helicobacter pylori eradication therapy including lansoprazole followed by lansoprazole monotherapy for gastroesophageal reflux disease.
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A patient receiving intradermal injections of vaccine directed towards carcinoembryonic antigen-bearing metastases from colorectal cancer showed uptake of 18F-fluorodeoxyglucose in local draining lymph nodes during the course of treatment.
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Patients with endophthalmitis fared more poorly than those with blebitis in terms of visual outcome.
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The IM route of administration was associated with higher mean daily doses (1.28 +/- 0.14 mg/day) than was oral administration (0.37 +/- 0.02 mg/day).
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Albeit rare among Western patients, such lithium-associated thyroid dysfunctions appeared to be more likely to occur in Hong Kong Chinese.
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Phenylpropanolamine (PPA) recently has been publicly implicated as a cause of stroke and other neurologic events.
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PURPOSE: The purpose of this report is to describe the management and outcome of an unusual complication of a commonly used chemotherapeutic agent.
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However, with increased experience in applying BCG, the side effects now appear to be less prominent and few.
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OBJECTIVE: To report a case of decreased international normalized ratio (INR) in a patient receiving warfarin and bosentan.
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This case highlights the possible development of acute coronary syndrome as a side effect of Capecitabine therapy.
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Gigantomastia induced by bucillamine.
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Continuous irregular rhythmic generalized 2.0-2.5 Hz sharp-and-slow wave complexes intermixed with spikes and polyspikes more prominent over the frontocentral areas were seen on the EEG.
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Although certain subgroups of patients have been shown to benefit from adjuvant therapy, continued efforts must be directed at identifying responders so that others will not be exposed to the additional risks of chemotherapy.
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CONCLUSIONS: Our experience indicates that safely flying with newly diagnosed DM type 1 is possible.
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The patient developed tonic-clonic seizures, which resolved with diazepam and midazolam therapy.
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This paper reports an autopsy case of a 78-year-old male with multiple nodules in the liver developed after long-termed administration of phosphate diethylstilbestrol (PDES) for prostatic cancer.
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We recommend the cautious use of ketorolac in patients with underlying illnesses where NSAID-induced ototoxicity could result in adverse otologic consequences.
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Orthostatic hypotension was also noted at that visit, with a standing blood pressure measurement of 95/80 mm Hg.
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We present three cases of women who developed acute transient myopia caused by drugs for gynecological problems.
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Two days later, the patient's QTc interval had decreased to 546 msec, and she was discharged home.
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Therapy with spironolactone and prednisone also normalized blood pressure.
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Data on the use of 25-OH D show no greater benefit than for vitamin D.
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The latter form (Macrodantin) is reported to engender less gastrointestinal intolerance but it can produce the same adverse effects as the conventional form--liver damage, acute and chronic pulmonary reactions, peripheral neuropathy, blood dyscrasias and allergic reactions--and does so just as rapidly and floridly; one such case is reported here.
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Infliximab and nephrotic syndrome.
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Only two of the six reported patients without heparinization survived.
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Apparent central nervous system depression in infants after the use of topical brimonidine.
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A search of MEDLINE (1966 to November 1998) and International Pharmaceutical Abstracts (1970 to November 1998) did not reveal a similar case.
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However, these patients may be admitted to an intensive care unit (ICU) with complications of Wolff Parkinson White (WPW) syndrome; for example post cardiopulmonary arrest or WPW as a co-morbidity.
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We have safely used recombinant factor VIIa to treat bleeding in the immediate and long-term period following PCC-related MI.
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The potential role of propranolol in inducing central nervous system disturbances is emphasized, and the literature on the subject is reviewed.
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Local administration of corticosteroids for rheumatic diseases have had a long history of effective and well-tolerated use.
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We describe a 73-year-old woman who developed serious systemic vasculitis with associated thrombocytopenia in the course of treatment with cladribine.
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In 6 patients with tumours secreting gastrin and/or glucagon, secretion of these peptides was acutely inhibited by SMS 201-995.
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Kaposi's sarcoma, a neoplasm that occurs in immunocompromised patients and people of Mediterranean origin, usually presents with skin lesions.
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Commonly reported adverse effects of the drug include nausea and vomiting, constipation, headache, and fatigue, as well as myelosuppression, which may be dose limiting.
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Moreover, these findings suggest that the incidence of BOOP following rituximab therapy may be higher than has been previously appreciated.
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Common peroneal nerve palsy following TNF-based isolated limb perfusion for irresectable extremity desmoid tumor.
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The latter revealed sensitization to PTU during the acute phase of the disease, which was greatly reduced 5 weeks after discontinuation of the drug and was completely absent after 5 months.
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Persistent hypoglycemia in a patient with diabetes taking etanercept for the treatment of psoriasis.
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Although case reports exist concerning the positive impact of lamotrigine addition on clozapine treatment in resistant schizophrenia, a review of the literature fails to document any evidence regarding a combination of the two in the treatment of patients with schizophrenia and comorbid alcohol dependence.
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With the use of optical coherence tomography (OCT), two patients with IFN-associated retinopathy who had developed macular edema and reduced visual acuity during the clinical course of IFN therapy were observed.
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Successful treatment of stutter priapism with an antiandrogen.
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In unusual conditions surgical removal of thrombi in dilated cardiomyopathy may be a safer alternative.
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With protein loss in the dialysate and a decreased serum albumin level, the patient developed ankle edema.
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Median haemoglobin nadir for patients with ALL and AML was 4.5 g/dL (range 1.3-6.9) and 5.1 g/dL (range 2.6-6.8), respectively.
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Most studies report incidence rates ranging from 1.5 to 3%.
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A case of hepatocellular carcinoma in a young female is presented in which the apparent etiology was the use of oral contraceptives for 5 1/2 years.
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The incidence of angioedema secondary to losartan, an angiotensin II receptor antagonist, is unknown.
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He was treated with prednisolone, cyclophosphamide, cytosine-arabinoside and chlorambucil for the following three and a half years.
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Seven patients with hematologic malignancies who were treated with miconazole for either suspected or proven fungal infections developed eight episodes of major adverse cardiorespiratory and anaphylactic reactions.
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We describe a case of soft tissue infection caused by Fusarium species in a heart-liver transplant recipient, and review the cases of fusarial infection reported among solid-organ transplant (SOT) recipients.
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It is a cumulative dose-dependent phenomenon reported to occur most often after 2 weeks of therapy.
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We therefore concluded that acute pancreatitis is a rare manifestation of systemic lupus erythematosus, and corticosteroids do not appear to be the etiological agent.
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The authors review the literature on this aspect and highlight the dangers of starting lithium treatment in patients with neurologic impairment.
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CONCLUSIONS: Postural epigastric pain as a sign of CMV gastritis is fairly rare in renal transplant recipients.
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Vasopressin (0.04 units/min) was administered through a peripheral venous catheter for hypotension unresponsive to exogenous catecholamines.
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Recently clinicians have begun to employ it in several oft label usages in children, especially behavioral syndromes.
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A 5-month-old infant became lethargic and poorly responsive after receiving 1 drop of brimonidine in each eye.
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Replicate brain magnetic resonance imaging examinations after six weeks and 11 months of penicillamine therapy documented the development of new brain lesions during this period, while liver biopsy specimen data disclosed that excellent hepatic decoppering had occurred.
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Pulse therapy may be equally as effective and may lessen the frequency of serious side effects.
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We report two cases of fulminant hepatic failure in HIV-1-infected patients treated with didanosine (ddI).
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A complication of the implantable constant infusion chemotherapy pump.
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With the increasing use of tacrolimus in steroid-resistant nephrotic syndrome, the treating physicians need to be aware of this rare, but potentially life-threatening side effect.
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A focal outbreak in a hospital.
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Larvae can penetrate the skin, are carried hematogenously to the lungs, migrate up the bronchial tree, and then can be passed to the upper small intestine.
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Even though steroids are well known to be effective on managing AIA and its nasal polyps, histochemical examinations after steroid therapy and at recurrence, involving eosinophil infiltration of nasal polyps, have been less studied.
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Rasburicase for the management of tumor lysis syndrome in neonates.
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Coexistence of bulimia nervosa and mania: a literature review and case report.
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Simultaneously with the clomipramine dosage increase, clozapine was tapered and stopped ever a period of 19 days.
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Diagnosis: practolol induced sclerosing peritonitis.
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The epigastric pain completely resolved after treatment with ganciclovir.
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A case report.
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Carbamazepine-induced systemic lupus erythematosus-like disease.
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Acute leukemia following combination chemotherapy for cancer of the lung.
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The maculopapular rash progressed to formation of confluent nodules, plaques and finally erythroderma with lymphadenopathy and hepatosplenomegaly.
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Ovarian hyperstimulation syndrome (OHS) is one of the potential complications associated with the use of human menopausal gonadotropin therapy.
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Prolonged responses were achieved with low doses of HU (3-10 mg/kg/day) and higher doses were associated with mild reversible hematologic or hepatic toxicity and no further increases in Hb.
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Toxic epidermal necrolysis (TEN) is a life-threatening bullous dermatosis characterized by the sudden onset of full-thickness epidermal necrosis.
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The most progressive neurological deficits like severe tetraspastic paresis, were seen only in the nondialytic renal insufficient group (3 patients), while the others had a more benign course of the disease.
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Taxanes are widely used chemotherapeutic agents with the potential to induce pulmonary injury through a variety of mechanisms.
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