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Hypersensitivity reactions involving the kidneys can occur with any of the penicillin groups.
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CASE SUMMARY: A 65-year-old patient chronically treated with the selective serotonin reuptake inhibitor (SSRI) citalopram developed confusion, agitation, tachycardia, tremors, myoclonic jerks and unsteady gait, consistent with serotonin syndrome, following initiation of fentanyl, and all symptoms and signs resolved following discontinuation of fentanyl.
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However, viral tests had remained positive for 8-39 days.
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There are very few reports about asterixis as a side effect of treatment with psychopharmacologic agents.
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This case extends the spectrum of fludarabine pulmonary toxicity to include pulmonary nodules.
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A total of 24 patients were identified and clinical information of varying detail was available in all cases.
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Successful treatment of disseminated Fusarium infection after autologous bone marrow transplantation for acute myeloid leukemia.
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Treatment with oral prednisolone resulted in some improvement in the cutaneous signs, particularly over the face, trunk and proximal limbs.
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After an extensive review of the literature, we believe that this is the first communication of the successful use of amiodarone to control hyperthyroidism in a patient with PTU-induced fulminant hepatitis.
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Aspergillus fumigatus keratitis following laser in situ keratomileusis.
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The fever abated promptly following discontinuation of acyclovir, and radiographic abnormalities resolved over ten days.
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We observed a decrease in nocturia frequency in all three patients, a decrease in irritative urinary symptoms in two and an improvement of sleep QOL in two.
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Histologically confirmed lymphoma with evidence of active EBV proliferation developed within cervical lymph nodes 3 weeks after his first autologous stem cell rescue.
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Toxicities included fever, skin rash, somnolence and a generalized seizure.
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An apparent link is described between the use of MMF with prednisone to treat pemphigus vulgaris and the development of red blood cell anemia.
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Reports in the literature of isolated agranulocytosis are few, although they may be associated with significant morbidity and mortality.
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Our series of 3 patients supports a causal connection between bleomycin and scleroderma.
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A seven-year-old boy with acute lymphoblastic leukemia received vincristine sulphate 1 mg, 1 ml intramuscularly, into his glutea, inadvertently, in the local hospital.
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CONCLUSIONS: Continuous infusion of local anesthetic and opioid to a sternal fracture site using a periosteally positioned catheter led to successful analgesia and hence improved respiratory function.
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IMPLICATIONS FOR NURSING PRACTICE: With any new treatment option, it is imperative that nurses understand how agents work to enrich their own knowledge base, as well as have a strong foundation for patient education.
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According to the Naranjo probability scale, this reaction was probable.
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Esmolol, an ultrashort-acting beta 1-selective antagonist, controlled her multiple dysrhythmias and symptoms of sympathetic nervous system hyperstimulation.
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She was successfully treated with oral prednisolone and cyclosporine A (CsA).
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A good partial remission was attained.
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The beta-lactam antibiotics are reported to induce convulsions caused by the suppression of inhibitory GABAergic functions.
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Treatment with topical and intracameral amphotericin B and systemic fluconazole, along with topical corticosteroids and intracameral t-PA, was successful in eradicating the corneal infiltrate and resolving intraocular inflammation.
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However, follow-up revealed that gestational diabetes when associated with norethisterone had a lesser risk of emerging diabetes mellitus and impaired glucose tolerance.
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Infants, particularly neonates, are not merely small adults requiring smaller dosages, but rather uniquely different patients.
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A 31 year old woman presented with a chest wall abscess due to Actinomyces israellii and Porphyromonas asaccharolytica (previously Bacteroides asaccharolyticus).
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Our institution has also adopted a similar combined therapy protocol for patients with stage III and IV nasopharyngeal cancer and good performance status.
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One month after surgery both patients were free of involuntary movements with an improvement of about 60% in the "off" state UPDRS motor score.
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RESULTS: Quetiapine was associated with leucopenia in two patients and clinically apparent agranulocytosis in one patient.
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A rare case of upbeating nystagmus, which occurred under the condition of a loss of visual fixation, due to anticonvulsant intoxication is reported.
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Extensive pelvic, pulmonary and brain metastases were associated with clinically manifest thyrotoxicosis.
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The patient had recurrence of urticaria and angioedema a year and a half later, at which point the NPH was stopped and she was desensitized to regular insulin.
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A renal biopsy showed diffuse mesangial proliferation with marked glomerular infiltration of macrophages and massive subendothelial and mesangial deposits.
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The long-term therapy necessary to eradicate the Mycobacterium tuberculosis organism makes economic considerations important.
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Etanercept and demyelinating disease in a patient with psoriasis.
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PURPOSE: Quetiapine is a novel antipsychotic, which is efficacious in the treatment of positive and negative symptoms in schizophrenia.
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Ramipril therapy resulted in an important reduction of proteinuria (0.3-0.5 g/24 h): no changes were observed in arterial pressure and renal function during the 12-month follow-up.
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Electrophysiologic data obtained before and during thyroxine replacement therapy showed that hypothyroidism lengthens the effective refractory period of the atria, AV node, bypass tract and His-Purkinje system (that in the ventricle not being measured); this lengthening resembles the effects of long-term administration of amiodarone.
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A patient presented with a painful, oedematous, cyanosed hand having injected a solution of diamorphine and methylphenidate into his radial artery.
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Any areas of obvious third-degree burns would be debrided and grafted.
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The patient developed a raised purple area of discoloration around the intravenous insertion site within 2 h and edema and vesiculobullous lesions of the distal forearm, hands, and fingers within 8 h.
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The patient's autoimmune thyroiditis may also contribute to the predisposition for pemphigus development.
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Twenty-four months after patient's discharge, her clinical condition, CBC, and bone marrow remained normal.
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Calotropis procera (ushaar) keratitis.
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A 32-year-old man with a family history of type 2 diabetes mellitus presented with circulatory collapse and deep coma after 9 days of treatment with perospirone hydrochloride, a recently developed atypical antipsychotic agent available only in Japan.
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The use of a plant fungicide, the imidazole imazalil, in the therapy of human alternariosis is described.
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Two of our patients had failed treatment with haloperidol and another had failed treatment with pimozide.
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No clinical side-effects or evidence of systemic activation of coagulation occurred during the treatment.
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OBJECTIVE: The aim of this study is to describe the efficacy and safety of risperidone, in the treatment of delusions of infestation.
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In contrast to that in other nephropathies, the role of renin-angiotensin blockade in kidney transplantation is less well defined, and its anti-proteinuric effect is markedly reduced in the presence of segmental glomerulosclerosis.
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However, the sphincterotomy did not improve cholestasis.
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These data indicate that the current methods for monitoring resistant mutants are potentially flawed because no tissue culture system adequately reflects the receptor specificity of human respiratory tract epithelium.
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Intracameral tPA injection resulted in complete resolution of hyphema in all 3 eyes.
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Arterial occlusion due to intraplaque hemorrhage and de novo thrombosis caused by thrombin-mediated platelet aggregation are also discussed as potential mechanisms of arterial occlusion.
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A review of the literature reveals this as a unique case.
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A 64 year old woman with previous history of coronary stenting five days before was admitted in our institution for intracranial bleeding while receiving aspirin and clopidogrel.
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Myeloma screen was negative; ANC >1,000 at day +7, platelets >50,000 at day +24.
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However, the use of atypical neuroleptics in modern psychopharmacotherapy is increasing, so the incidence of NMS under these drugs may also increase.
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Histologic examination of skin biopsy specimens from the patients' UV-B and UV-A test sites and lesional skin revealed an acute eczematous dermatitis.
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Administration of steroid and decreasing the dose of PTU produced a good clinical response and the ANCA disappeared.
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The diagnosis of pseudomembranous colitis was made by flexible sigmoidoscopy and a positive stool specimen for Clostridium difficile toxin.
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Quetiapine-induced leucopenia and thrombocytopenia.
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However, since maternal death has occurred with postpartum vulvar edema, the patient with vulvar edema merits special attention.
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Because pain perception involves both serotonergic and noradrenergic mechanisms, venlafaxine also may be useful in neuropathic pain therapy.
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This case is unique in that interstitial lung disease evolved in parallel with colitis and caused severe hypoxemia.
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Intracavernous self-injection with vasoactive drugs is a new treatment for impotence.
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RESULTS: The patient's serum from 10 days after the episode, only when therapeutic concentrations of oxaliplatin were added, reacted with all RBCs tested using the indirect antiglobulin test (IAT) (3+).
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The attending or consulting physicians assessed that acute hemolysis or DIC caused or contributed to each death.
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The ocular motor disturbances are probably an expression of regional 5-FU neurotoxicity primarily affecting the brain stem.
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From the literature, 72 references were reviewed.
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Fifty days after the first UCBT, the patient underwent a second UCBT with a reduced-intensity conditioning regimen.
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A patient with biventricular thrombus formation in dilated cardiomyopathy suffered massive combined systemic and pulmonary embolization shortly after oral anticoagulation was started.
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An unusual case of Ecstasy poisoning.
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Potential advantages and disadvantages of using epinephrine in this setting, the role of alpha-agonists and some potential mechanisms accounting for their role in successful management are reviewed.
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Patients finally rated their subjective impression on this intervention.
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Clinical responses were noted within 3 to 7 days of initiation of treatment.
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Respiratory failure in Wegener's granulomatosis: response to pulse intravenous methylprednisolone and cyclophosphamide.
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This complication was dose related and argues for caution when initiating intrathecal therapy with amphotericin B at doses greater than 0.025 mg.
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We describe 2 patients with prior amputation who experienced phantom limb pain (PLP) after receiving paclitaxel therapy.
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The case history and toxicological findings of an infant fatality involving pseudoephedrine, brompheniramine, and dextromethorphan are presented.
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Thoracoscopic biopsy to confirm metastasis revealed instead fibrotic lesions apparently attributable to bleomycin or cyclophosphamide.
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The distinctive histopathological findings led to the correct diagnosis despite sparse clinical information.
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This is an important pitfall because, when diagnosed early, bleeding in these patients is treatable.
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Two patients underwent penetrating keratoplasty at 22 and 26 months after the onset of symptoms and have maintained clear grafts with no evidence of recurrence.
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The literature, except for anecdotal reports, does not support a significant increase of ulcers in asthmatic patients on either theophylline or steroids.
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Hypertensive reactions occurred without obvious cause in two patients receiving monoamine oxidase inhibitors (MAOIs) while being monitored in a hospital.
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CONCLUSION: This case highlights the importance of timely application of aggressive measures even in patients with known diagnosis of a fatal malignancy as these interventions can prolong life and be of palliative benefit.
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We report a case of AILD in an 80-year-old male who presented with a generalized pruritic maculopapular eruption and fever following doxycycline administration.
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The sulfonamides are the best verified drug-trigger for erythema multiforme and Stevens-Johnson syndrome.
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A case of cicatricial pemphigoid with circulating IgA and IgG antibodies directed against 280 kD, 165 kD and 120-130 kD epidermal antigens.
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A 7-year-old with congenital toxoplasmosis who took pyrimethamine and sulfadiazine for reactivated chorioretinitis developed fever, severe cutaneous involvement, swelling, abdominal pain and transaminitis, persisting weeks after withholding medicines.
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No published reports, however, exist of exfoliative disease after treatment with levofloxacin.
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METHOD: The authors followed a patient with chronic HCV who received interferon and ribavirin and who developed hallucinations ultimately requiring psychiatric hospitalization.
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Striking regression of radiation-induced fibrosis by a combination of pentoxifylline and tocopherol.
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Ovadendron sulphureo-ochraceum endophthalmitis after cataract surgery.
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The persistent effects of methotrimeprazine meleate on various organs are typical of the prolonged biological action of the phenothiazine metabolites.
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CONCLUSIONS: We believe this case to be the first report of this type of reaction owing to tadalafil.
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