text
stringlengths 57
1.72k
| relation
stringclasses 125
values | h
dict | t
dict |
|---|---|---|---|
[ study of the thyrotropic hormone content of the anterior pituitary after ablation of the posterior pituitary ] . | NA | {
"id": "C0040160",
"name": "thyrotropic hormone",
"pos": [
15,
34
]
} | {
"id": "C0032016",
"name": "anterior pituitary",
"pos": [
50,
68
]
} |
[ vertebro-basilar arterial insufficiency caused by obliteration of the 1st segment of the subclavian artery ( or of the brachiocephalic arterial trunk ) . ( subclavian steal syndrome ) . diagnosis and treatment ] . | NA | {
"id": "C0042568",
"name": "vertebro-basilar arterial insufficiency",
"pos": [
2,
41
]
} | {
"id": "C0038531",
"name": "subclavian steal syndrome",
"pos": [
158,
183
]
} |
infrared and ultraviolet studies on the tautomeric equilibria in aqueous medium between monoanionic species of uracil , thymine , 5-fluorouracil , and other 2,4-diketopyrimidines . | NA | {
"id": "C0041917",
"name": "uracil",
"pos": [
111,
117
]
} | {
"id": "C0040087",
"name": "thymine",
"pos": [
120,
127
]
} |
infrared and ultraviolet studies on the tautomeric equilibria in aqueous medium between monoanionic species of uracil , thymine , 5-fluorouracil , and other 2,4-diketopyrimidines . | NA | {
"id": "C0041917",
"name": "uracil",
"pos": [
111,
117
]
} | {
"id": "C0016360",
"name": "5-fluorouracil",
"pos": [
130,
144
]
} |
selective chemical modifications of uridine and pseudouridine in polynucleotides and their effect on the specificities of ribonuclease and phosphodiesterases . | NA | {
"id": "C0041984",
"name": "uridine",
"pos": [
36,
43
]
} | {
"id": "C0033846",
"name": "pseudouridine",
"pos": [
48,
61
]
} |
investigation of hypoalbuminemia in an elderly woman with a large papillary adenocarcinoma of the cecum revealed that the hypoproteinemia was due to excessive loss of plasma albumin into the intestinal tract . | NA | {
"id": "C0239981",
"name": "hypoalbuminemia",
"pos": [
17,
32
]
} | {
"id": "C0020639",
"name": "hypoproteinemia",
"pos": [
122,
137
]
} |
protein turbidity produced by trichloracetic acid and sulfosalicylic acid at varying temperatures and varying ratios of albumin and globulin . | NA | {
"id": "C0033684",
"name": "protein",
"pos": [
0,
7
]
} | {
"id": "C0001924",
"name": "albumin",
"pos": [
120,
127
]
} |
protein turbidity produced by trichloracetic acid and sulfosalicylic acid at varying temperatures and varying ratios of albumin and globulin . | NA | {
"id": "C0033684",
"name": "protein",
"pos": [
0,
7
]
} | {
"id": "C0017649",
"name": "globulin",
"pos": [
132,
140
]
} |
[ studies on the permeability of the blood-brain , blood-cerebro-spinal fluid and cerebro-spinal fluid-brain barriers for proteins under physiological conditions and of the blood-brain barrier for albumins in cerebral edema ] . | NA | {
"id": "C0033684",
"name": "proteins",
"pos": [
122,
130
]
} | {
"id": "C0001924",
"name": "albumins",
"pos": [
197,
205
]
} |
[ vertebro-basilar arterial insufficiency caused by obliteration of the 1st segment of the subclavian artery ( or of the brachiocephalic arterial trunk ) . ( subclavian steal syndrome ) ] . | NA | {
"id": "C0042568",
"name": "vertebro-basilar arterial insufficiency",
"pos": [
2,
41
]
} | {
"id": "C0038531",
"name": "subclavian steal syndrome",
"pos": [
158,
183
]
} |
[ influence of pituitary gonadotropins ( fsh and lth ) on oscillations of circulating eosinophils after bilateral ovariectomy ] . | NA | {
"id": "C0018066",
"name": "pituitary gonadotropins",
"pos": [
15,
38
]
} | {
"id": "C0033371",
"name": "lth",
"pos": [
49,
52
]
} |
[ development of the adrenal content of adrenaline and noradrenaline during postnatal development in the vole ] . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
40,
50
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
55,
68
]
} |
immunodiffusion and quantitative precipitin studies , as well as cross-neutralization tests , indicate that b. stearothermophilus alpha-amylase reacts with a portion of antibody present in antisera to crystalline b. subtilis alpha-amylase . | NA | {
"id": "C0003241",
"name": "antibody",
"pos": [
169,
177
]
} | {
"id": "C0020960",
"name": "antisera",
"pos": [
189,
197
]
} |
1965.-the conversion of fructose-1,6-diphosphate to fructose-6-phosphate ( fructose-1,6-diphosphatase activity ) is essential for growth of escherichia coli on glycerol , acetate , or succinate , but is unnecessary for growth on hexoses or pentoses . | NA | {
"id": "C0016745",
"name": "fructose",
"pos": [
24,
32
]
} | {
"id": "C0019494",
"name": "hexoses",
"pos": [
229,
236
]
} |
it has sometimes been assumed that fructose-1,6-diphosphatase activity is due to a nonspecific acid hexose phosphatase . | NA | {
"id": "C0016745",
"name": "fructose",
"pos": [
35,
43
]
} | {
"id": "C0019494",
"name": "hexose",
"pos": [
100,
106
]
} |
these mutants still possess the nonspecific acid hexose phosphatase , which does not require mg ( ++ ) and is active only at much higher concentrations of fructose-1,6-diphosphate . | NA | {
"id": "C0019494",
"name": "hexose",
"pos": [
49,
55
]
} | {
"id": "C0016745",
"name": "fructose",
"pos": [
155,
163
]
} |
at a concentration of 2.2 x 10 ( -5 ) m fu , the yield of phage was reduced to 15 % of that in an uninhibited control , 28 % of the phage rna uracil was replaced with fu , and the specific infectivity of the phage was unaltered . | NA | {
"id": "C0041917",
"name": "uracil",
"pos": [
142,
148
]
} | {
"id": "C0016360",
"name": "fu",
"pos": [
167,
169
]
} |
neither the synthesis of ribosomal ribonucleic acid ( rna ) nor that of the rapidly labeled rna of the cell nucleus is inhibited before 10 hr after infection . | NA | {
"id": "C0035701",
"name": "ribosomal ribonucleic acid",
"pos": [
25,
51
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
92,
95
]
} |
factors relating to the binding of benzo [ a ] pyrene ( benzo [ a ] pyrene uptake ) have been studied in detail with escherichia coli ma , a triple auxotroph requiring l-leucine , uracil , and thymine . | NA | {
"id": "C0041917",
"name": "uracil",
"pos": [
180,
186
]
} | {
"id": "C0040087",
"name": "thymine",
"pos": [
193,
200
]
} |
[ study of the development of bradykinin- and kallidin-induced edema in the adrenalectomized rat . influence of adrenalectomy on the inhibitory capacity of sodium salicylate and phenylbutazone ] . | NA | {
"id": "C0006100",
"name": "bradykinin",
"pos": [
30,
40
]
} | {
"id": "C0022474",
"name": "kallidin",
"pos": [
46,
54
]
} |
effect of carnitine on acidosis and ketosis induced by lipid perfusions in dogs during starvation . | NA | {
"id": "C0001122",
"name": "acidosis",
"pos": [
23,
31
]
} | {
"id": "C0022638",
"name": "ketosis",
"pos": [
36,
43
]
} |
radioactivity in blood and liver partial glycerides , and liver phospholipids after intravenous administration to carbohydrate-fed rats of chyle containing double-labeled triglycerides . | NA | {
"id": "C0017860",
"name": "glycerides",
"pos": [
41,
51
]
} | {
"id": "C0041004",
"name": "triglycerides",
"pos": [
171,
184
]
} |
in comparison , the nucleic acids of m. gallinarum and m. gallisepticum were incapable of binding the labeled dna of h. gallinarum . | NA | {
"id": "C0028606",
"name": "nucleic acids",
"pos": [
20,
33
]
} | {
"id": "C0012854",
"name": "dna",
"pos": [
110,
113
]
} |
[ the value of studies on the clotting mechanism for the diagnosis of liver diseases . ii . hepatitis and fibrinolysis ] . | NA | {
"id": "C0023895",
"name": "the",
"pos": [
2,
5
]
} | {
"id": "C0019158",
"name": "hepatitis",
"pos": [
92,
101
]
} |
mixtures of h or l chains from anti-p-azobenzoate ( xp ) antibody and the complementary chains from antibody-depleted gammag-immunoglobulin show little hapten-binding . | NA | {
"id": "C1302674",
"name": "chains",
"pos": [
19,
25
]
} | {
"id": "C0021027",
"name": "immunoglobulin",
"pos": [
125,
139
]
} |
[ late and tenacious allergic manifestations of the skin in connection with intestinal parasitoses ( strongyloidosis and lambliasis ) ] . | NA | {
"id": "C0021832",
"name": "intestinal parasitoses",
"pos": [
76,
98
]
} | {
"id": "C0017536",
"name": "lambliasis",
"pos": [
121,
131
]
} |
its incorporation into depot fats and into lipids of the vitellus of the laid egg ] . | NA | {
"id": "C0015677",
"name": "fats",
"pos": [
29,
33
]
} | {
"id": "C0023779",
"name": "lipids",
"pos": [
43,
49
]
} |
[ effects of gamma rays on pyrimidine bases in the solid state . i. effects on uracil and thymine ] . | NA | {
"id": "C0041917",
"name": "uracil",
"pos": [
79,
85
]
} | {
"id": "C0040087",
"name": "thymine",
"pos": [
90,
97
]
} |
[ data on the hormonogenesis and metabolism of corticosteroids in cushing 's disease : differential chromatography of 17-ketosteroids ] . | NA | {
"id": "C0001617",
"name": "corticosteroids",
"pos": [
47,
62
]
} | {
"id": "C0000167",
"name": "17-ketosteroids",
"pos": [
118,
133
]
} |
[ chemical structure of diphtherial toxin and toxoid . 3. c-terminal amino acid of diphtherial toxin and toxoid ] . | NA | {
"id": "C0012551",
"name": "toxoid",
"pos": [
46,
52
]
} | {
"id": "C0040555",
"name": "toxoid",
"pos": [
105,
111
]
} |
guinea pigs injected with 100 micrograms of p-azobenzenearsonate derivatives of hexa-l-tyrosine , tri-l-tyrosine , or n-acetyl-l-tyrosine amide , in complete freund 's adjuvant , developed , after 10 to 19 days , delayed-type hypersensitivity to these substances . | NA | {
"id": "C0041485",
"name": "tyrosine",
"pos": [
87,
95
]
} | {
"id": "C0067794",
"name": "n-acetyl-l-tyrosine",
"pos": [
118,
137
]
} |
paramagnetic cations quench the phosphorescence of dna at concentrations well below one ion per dna phosphate . | NA | {
"id": "C0007447",
"name": "cations",
"pos": [
13,
20
]
} | {
"id": "C0022023",
"name": "ion",
"pos": [
88,
91
]
} |
since only thymus glands of animals treated with antiserum to thymus showed depletion of small lymphocytes , antibody to thymic humoral factor may be operational . | NA | {
"id": "C0020960",
"name": "antiserum",
"pos": [
49,
58
]
} | {
"id": "C0003241",
"name": "antibody",
"pos": [
109,
117
]
} |
in addition double staining for one allotype and gamma g globulins in the lymphoid tissues of rabbits homozygous at the a or at the b locus , has shown the presence of cells containing immunoglobulins that lack one allotype . | NA | {
"id": "C0017007",
"name": "gamma",
"pos": [
49,
54
]
} | {
"id": "C0021027",
"name": "immunoglobulins",
"pos": [
185,
200
]
} |
[ muscular glycogenosis caused by alpha-1,4-glucosidase deficiency simulating progressive muscular dystrophy . ( clinical and enzyme study . optic and electron microscopy ) ] . | NA | {
"id": "C0017919",
"name": "glycogenosis",
"pos": [
11,
23
]
} | {
"id": "C0017921",
"name": "alpha-1,4-glucosidase deficiency",
"pos": [
34,
66
]
} |
the incorporation of uniformly labeled l-lysine-c ( 14 ) into the normal and regenerating rat liver , into novikoff hepatoma histones , and into acidic nuclear proteins was studied . | NA | {
"id": "C0019652",
"name": "histones",
"pos": [
125,
133
]
} | {
"id": "C0028589",
"name": "nuclear",
"pos": [
152,
159
]
} |
in the hepatoma cells the ratio of the biosynthesized acidic nuclear proteins to histones was altered . | NA | {
"id": "C0028589",
"name": "nuclear proteins",
"pos": [
61,
77
]
} | {
"id": "C0019652",
"name": "histones",
"pos": [
81,
89
]
} |
[ appearance of quincke 's edema , urticaria and bronchial asthma seizures after the intravenous administration of 10 per cent calcium chloride solution ] . | NA | {
"id": "C0002994",
"name": "quincke 's edema",
"pos": [
16,
32
]
} | {
"id": "C0042109",
"name": "urticaria",
"pos": [
35,
44
]
} |
the biochemical effects of these drugs will involve several substrates of mao , e.g . dopamine , tyramine , serotonin and , to a lesser extent , noradrenaline and adrenaline.mao probably regulates the metabolism of catecholamines and serotonin in tissues , while catechol-o-methyltransferase is responsible for the metabolism of circulating noradrenaline and adrenaline . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
145,
158
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
359,
369
]
} |
indirectly acting sympathomimetic amines , such as amphetamines , ephedrine and maoi with amphetamine-like properties , can be potentiated , because they may release increased amounts of nor-adrenaline from sympathetic nerve endings after mao inhibition . | NA | {
"id": "C0002667",
"name": "amphetamines",
"pos": [
51,
63
]
} | {
"id": "C0002658",
"name": "amphetamine",
"pos": [
90,
101
]
} |
enzyme activity was inhibited by p-chloromercuribenzoate at relatively high concentrations , by hg ( ++ ) or zn ( ++ ) ions , and to a lesser extent by several other metal cations . | NA | {
"id": "C0022023",
"name": "ions",
"pos": [
86,
90
]
} | {
"id": "C0007447",
"name": "cations",
"pos": [
172,
179
]
} |
1965.-the folic acid analogues , 2,4-diamino-6-methylpteridine , amethopterin , and aminopterin , have been found to sensitize certain bacteria , especially escherichia coli , to the lethal action of ionizing irradiation . | NA | {
"id": "C0025677",
"name": "amethopterin",
"pos": [
65,
77
]
} | {
"id": "C0002583",
"name": "aminopterin",
"pos": [
84,
95
]
} |
incorporation of c ( 14 ) -labeled glycine , serine , threonine , alanine , and proline into both cellular and exocellular protein was two to five times higher when these were supplied as components of dialyzable peptides rather than as free amino acids . | NA | {
"id": "C0017890",
"name": "glycine",
"pos": [
35,
42
]
} | {
"id": "C0002520",
"name": "amino acids",
"pos": [
242,
253
]
} |
incorporation of c ( 14 ) -labeled glycine , serine , threonine , alanine , and proline into both cellular and exocellular protein was two to five times higher when these were supplied as components of dialyzable peptides rather than as free amino acids . | NA | {
"id": "C0001898",
"name": "alanine",
"pos": [
66,
73
]
} | {
"id": "C0002520",
"name": "amino acids",
"pos": [
242,
253
]
} |
water-soluble amino acids include leucine or norleucine ( or both ) , valine , gamma-amino-n-butyric acid , beta-amino-n-butyric acid , ergothionine , glutamic acid , glutamine , glycine , aspartic acid , asparagine , cystine , and cystathionine . | NA | {
"id": "C0002520",
"name": "amino",
"pos": [
14,
19
]
} | {
"id": "C0017890",
"name": "glycine",
"pos": [
179,
186
]
} |
water-soluble amino acids include leucine or norleucine ( or both ) , valine , gamma-amino-n-butyric acid , beta-amino-n-butyric acid , ergothionine , glutamic acid , glutamine , glycine , aspartic acid , asparagine , cystine , and cystathionine . | NA | {
"id": "C0061472",
"name": "glutamic acid",
"pos": [
151,
164
]
} | {
"id": "C0017797",
"name": "glutamine",
"pos": [
167,
176
]
} |
thus , inducer may increase the differential metabolic stability of the corresponding messenger ribonucleic acid ( rna ; defined as the capacity to produce measurable enzyme ) in inducible strains . | NA | {
"id": "C0035696",
"name": "messenger ribonucleic acid",
"pos": [
86,
112
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
115,
118
]
} |
c ( 14 ) -5-fu , like uracil , does appear to enter cells without measurable lag , saturating the pool of uracil nucleotides , and thereby the messenger rna being formed , within several minutes . | NA | {
"id": "C0016360",
"name": "5-fu",
"pos": [
10,
14
]
} | {
"id": "C0041917",
"name": "uracil",
"pos": [
106,
112
]
} |
role of aminoacyl-transfer ribonucleic acid in the regulation of ribonucleic acid synthesis in escherichia coli . | NA | {
"id": "C0035711",
"name": "transfer ribonucleic acid",
"pos": [
18,
43
]
} | {
"id": "C0035668",
"name": "ribonucleic",
"pos": [
65,
76
]
} |
role of aminoacyl-transfer ribonucleic acid in the regulation of ribonucleic acid synthesis in escherichia coli . | NA | {
"id": "C0035711",
"name": "transfer ribonucleic acid",
"pos": [
18,
43
]
} | {
"id": "C0035668",
"name": "ribonucleic acid",
"pos": [
65,
81
]
} |
1965.-a leucine auxotroph of escherichia coli was examined for its rate of ribonucleic acid ( rna ) synthesis and the level of charged leucine- , arginine- , and valine-specific transfer rna ( trna ) during the exponential growth period and when growth was limited by leucine starvation . | NA | {
"id": "C0035668",
"name": "ribonucleic acid",
"pos": [
75,
91
]
} | {
"id": "C0035711",
"name": "transfer rna",
"pos": [
178,
190
]
} |
present studies with heme-requiring strain 23 showed that protoheme was replaced by various porphyrins , uroporphyrinogen , coproporphyrinogen , certain iron-free metalloporphyrins , hemes , and certain heme-proteins containing readily removable hemes . | NA | {
"id": "C0032712",
"name": "porphyrins",
"pos": [
92,
102
]
} | {
"id": "C0025541",
"name": "metalloporphyrins",
"pos": [
163,
180
]
} |
present studies with heme-requiring strain 23 showed that protoheme was replaced by various porphyrins , uroporphyrinogen , coproporphyrinogen , certain iron-free metalloporphyrins , hemes , and certain heme-proteins containing readily removable hemes . | NA | {
"id": "C0025541",
"name": "metalloporphyrins",
"pos": [
163,
180
]
} | {
"id": "C0018966",
"name": "hemes",
"pos": [
246,
251
]
} |
strain 23 , two other strains representing predominant biotypes of b. ruminicola subsp . ruminicola , and one closely related strain grew in media containing heme-free protoporphyrin , mesoporphyrin , hematoporphyrin , or deuteroporphyrin , apparently inserting iron into several nonvinyl porphyrins . | NA | {
"id": "C0033733",
"name": "protoporphyrin",
"pos": [
168,
182
]
} | {
"id": "C0032712",
"name": "porphyrins",
"pos": [
289,
299
]
} |
porphobilinogen and porphyrin synthesis , apparently via the commonly known heme synthesis pathway , occurred during growth of heme-independent b. ruminicola subsp . brevis strain ga33 in a tetrapyrrole-free medium containing delta-aminolevulinic acid , but delta-aminolevulinic acid metabolism to porphobilinogen or porphyrins could not be detected in cells of heme-requiring strain 23 grown in the same medium with hemin added . | NA | {
"id": "C0018966",
"name": "heme",
"pos": [
76,
80
]
} | {
"id": "C0018988",
"name": "hemin",
"pos": [
417,
422
]
} |
[ study of oral hypoglycemic agents . vi . comparative study on acute oral overload using tolbutamide and tolazamide in normal and diabetic subjects . various aspects of the prolonged use of tolazamide in comparison with other sulfonylureas ] . | NA | {
"id": "C0040374",
"name": "tolbutamide",
"pos": [
90,
101
]
} | {
"id": "C0038766",
"name": "sulfonylureas",
"pos": [
227,
240
]
} |
[ study of oral hypoglycemic agents . vi . comparative study on acute oral overload using tolbutamide and tolazamide in normal and diabetic subjects . various aspects of the prolonged use of tolazamide in comparison with other sulfonylureas ] . | NA | {
"id": "C0040372",
"name": "tolazamide",
"pos": [
106,
116
]
} | {
"id": "C0038766",
"name": "sulfonylureas",
"pos": [
227,
240
]
} |
[ effects of an inhibitor of corticosteroid biosynthesis , metopyrone , on the quantities of adrenaline and noradrenaline present in the adrenals of the rat ] . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
93,
103
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
108,
121
]
} |
activity of bacteriophage t4 neutralizing antiserums obtained 8 days after a primary immunization of rabbits with purified phage t4 is due to antibodies of the 19s ( igm ) type . | NA | {
"id": "C0020960",
"name": "antiserums",
"pos": [
42,
52
]
} | {
"id": "C0003241",
"name": "antibodies",
"pos": [
142,
152
]
} |
[ metabolic changes of the brain in non-fatal potassium cyanide poisoning and its modification by cyanide antagonists ] . | NA | {
"id": "C0032826",
"name": "potassium cyanide",
"pos": [
46,
63
]
} | {
"id": "C0010505",
"name": "cyanide",
"pos": [
98,
105
]
} |
effect of blood volume on movement of protein and volume distribution of albumin in the dog . | NA | {
"id": "C0033684",
"name": "protein",
"pos": [
38,
45
]
} | {
"id": "C0001924",
"name": "albumin",
"pos": [
73,
80
]
} |
exchange between protein and water in the cryosublimation step of the linderstromlang method of deuterium-hydrogen exchange analysis . | NA | {
"id": "C0011744",
"name": "deuterium",
"pos": [
96,
105
]
} | {
"id": "C0020275",
"name": "hydrogen",
"pos": [
106,
114
]
} |
[ on the action of heparin , heparinoids and carrageenin on the components of guinea pig complements in vitro ] . | NA | {
"id": "C0019134",
"name": "heparin",
"pos": [
19,
26
]
} | {
"id": "C0019142",
"name": "heparinoids",
"pos": [
29,
40
]
} |
[ on the effect of glutamine , glutamic acid and alpha-ketoglutaric acid on the o2 uptake and nh3 formation of rabbit reticulocytes ] . | NA | {
"id": "C0017797",
"name": "glutamine",
"pos": [
19,
28
]
} | {
"id": "C0061472",
"name": "glutamic acid",
"pos": [
31,
44
]
} |
effects of several sympathomimetic amines ( levarterenol , phenylephrine , and epinephrine ) on coronary blood flow during cardiopulmonary bypass . | NA | {
"id": "C0028351",
"name": "levarterenol",
"pos": [
44,
56
]
} | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
79,
90
]
} |
[ aerosol immunization with dry living vaccines and toxoids . iii . study in experiment of the effectiveness of aerosol immunization with dry dust-like vaccines ( anthrax , brucellosis , tularemia and plague ) ] . | NA | {
"id": "C0040555",
"name": "toxoids",
"pos": [
52,
59
]
} | {
"id": "C0042210",
"name": "vaccines",
"pos": [
152,
160
]
} |
[ ecto-mesodermal hamartosis : a case of diffuse angiomatosis with fusion of sturge-weber-krabbe disease and parkes-weber disease ] . | NA | {
"id": "C0002992",
"name": "diffuse angiomatosis",
"pos": [
41,
61
]
} | {
"id": "C0038505",
"name": "sturge-weber",
"pos": [
77,
89
]
} |
[ on the behavior of some enzymatic activities in neoplastic tissues ( glutamic-oxalacetic transaminases , glutamic-pyruvic transaminases , aldolase , lactic hydrogenase and malic dehydrogenase ) . ii . neoplasms of the digestive tract ] . | NA | {
"id": "C0002594",
"name": "transaminases",
"pos": [
91,
104
]
} | {
"id": "C0001899",
"name": "glutamic-pyruvic transaminases",
"pos": [
107,
137
]
} |
[ diazo derivates of amino acids and peptides as possible antineoplastic chemotherapeutic agents . iii . activity on galliera sarcoma of 2 n-diazoacetyl derivatives of glycine in comparison with azaserine and don ] . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
21,
32
]
} | {
"id": "C0017890",
"name": "glycine",
"pos": [
168,
175
]
} |
[ action of chlorpropamide on hepatic function in diabetics treated over a long period with the so-called sulfonylureas ] . | NA | {
"id": "C0008287",
"name": "chlorpropamide",
"pos": [
12,
26
]
} | {
"id": "C0038766",
"name": "sulfonylureas",
"pos": [
106,
119
]
} |
[ anatomo-histological features of the principal pneumoconioses ( anthracosis , silicosis , asbestosis ) and their evaluation with respect to cor pulmonale , tuberculosis and lung cancer ] . | NA | {
"id": "C0032273",
"name": "pneumoconioses",
"pos": [
49,
63
]
} | {
"id": "C0003165",
"name": "anthracosis",
"pos": [
66,
77
]
} |
[ anatomo-histological features of the principal pneumoconioses ( anthracosis , silicosis , asbestosis ) and their evaluation with respect to cor pulmonale , tuberculosis and lung cancer ] . | NA | {
"id": "C0032273",
"name": "pneumoconioses",
"pos": [
49,
63
]
} | {
"id": "C0003949",
"name": "asbestosis",
"pos": [
92,
102
]
} |
[ incompetence of the uterine cervix as a cause of habitual abortion . review of the literature . report of cases ] . | NA | {
"id": "C0007871",
"name": "incompetence",
"pos": [
2,
14
]
} | {
"id": "C0000809",
"name": "habitual abortion",
"pos": [
51,
68
]
} |
[ study of the origin of fecal sterols in the rat by means of radioactive indicators . 3. influence of the level of dietary cholesterol on the quantities of cholesterol excreted via the bile and via the intestinal wall ] . | NA | {
"id": "C0008395",
"name": "dietary cholesterol",
"pos": [
116,
135
]
} | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
157,
168
]
} |
[ cytochemical and histoautoradiographic contribution to the study of the metabolism and synthesis of desoxyribonucleic acids in animal cells cultured in vitro . i. cytophotometric and histoautoradiographic studies on desoxyribonucleic acids in myleran-treated fibroblasts ] . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
136,
141
]
} | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
261,
272
]
} |
the effects of a purified bacterial lipopolysaccharide endotoxin on homogenous populations of rabbit polymorphonuclear leucocytes have been studied in vitro under defined conditions . | NA | {
"id": "C0014264",
"name": "bacterial",
"pos": [
26,
35
]
} | {
"id": "C0023810",
"name": "lipopolysaccharide",
"pos": [
36,
54
]
} |
in the presence of 10 per cent serum all concentrations of endotoxin enhanced phagocytosis , whereas at lower serum concentrations , the higher doses of lipopolysaccharide inhibited the phagocytic activity of the cells . | NA | {
"id": "C0014264",
"name": "endotoxin",
"pos": [
59,
68
]
} | {
"id": "C0023810",
"name": "lipopolysaccharide",
"pos": [
153,
171
]
} |
[ relation between cholinesterase activity and incorporation of amino acids into proteins . ii . incorporation of c14-labeled glycine into homogenized tissue of tumor homo- and heterografts under the influence of acetylphosphate ] . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
64,
75
]
} | {
"id": "C0017890",
"name": "glycine",
"pos": [
126,
133
]
} |
[ relation between cholinesterase activity and incorporation of amino acids into proteins . i. incorporation of c14-labeled glycine into homogenized liver tissue of the mouse under the influence of acetylphosphate ] . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
64,
75
]
} | {
"id": "C0017890",
"name": "glycine",
"pos": [
124,
131
]
} |
[ the content of adenine nucleotide , creatine phosphate , coenzyme a , glycogen and lactic acid in the brain of white mice in ether excitation and anesthesia ] . | NA | {
"id": "C0001413",
"name": "adenine nucleotide",
"pos": [
17,
35
]
} | {
"id": "C0009226",
"name": "coenzyme a",
"pos": [
59,
69
]
} |
in 16 dog heart-lung preparations modified to permit a more accurate measurement of coronary flow , adrenaline or noradrenaline was infused at a rate of 4 mug . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
100,
110
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
114,
127
]
} |
it was found that , mole per mole , noradrenaline is as effective , and probably more so , than adrenaline in raising the oxygen consumption of the heart-lung preparation . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
36,
49
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
96,
106
]
} |
the level of high-energy phosphorus compounds does not change after adrenaline or noradrenaline administration even at the time when the oxygen consumption rises to as much as 200 % . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
68,
78
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
82,
95
]
} |
single doses of 5 mug . adrenaline or noradrenaline have a consistent positive inotropic effect that lasts about 15 min . when tested on a failing heart . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
24,
34
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
38,
51
]
} |
[ current status of the problem of reticulosis . special study of its digestive syndromes ( hepatospleno-enteral ) and its relation with diseases caused by autoagression or homologous disease in man ] . | NA | {
"id": "C0039082",
"name": "syndromes",
"pos": [
80,
89
]
} | {
"id": "C0012634",
"name": "diseases",
"pos": [
137,
145
]
} |
[ bronchial asthma or genuine hyperventilation tetany ? contribution to the differential diagnosis and therapy of paroxysmal respiratory function disorders ] . | NA | {
"id": "C0020578",
"name": "hyperventilation",
"pos": [
30,
46
]
} | {
"id": "C0035204",
"name": "respiratory function",
"pos": [
125,
145
]
} |
[ the syndrome of multiple malformations associated with gonadal dysgenesis ( turner syndrome ) with xo chromosome formula ] . | NA | {
"id": "C0018051",
"name": "gonadal dysgenesis",
"pos": [
57,
75
]
} | {
"id": "C0041408",
"name": "turner syndrome",
"pos": [
78,
93
]
} |
[ the use of chlorothiazide ( and of hydrochlorothiazide ) in polyurodipsia . i. the facts . their diagnostic interest ] . | NA | {
"id": "C0008273",
"name": "chlorothiazide",
"pos": [
13,
27
]
} | {
"id": "C0020261",
"name": "hydrochlorothiazide",
"pos": [
37,
56
]
} |
[ the use of chlorothiazide ( and of hydrochlorothiazide ) in the syndrome of polyurodipsia . ii . therapeutic interest and physiopathology ] . | NA | {
"id": "C0008273",
"name": "chlorothiazide",
"pos": [
13,
27
]
} | {
"id": "C0020261",
"name": "hydrochlorothiazide",
"pos": [
37,
56
]
} |
this response was not obtained with phenethylamine , tyramine , ephedrine , or mescaline , nor with histamine , nor with the basic n-alkylamines . | NA | {
"id": "C0031399",
"name": "phenethylamine",
"pos": [
36,
50
]
} | {
"id": "C0014479",
"name": "ephedrine",
"pos": [
64,
73
]
} |
[ decrease in the basal temperature after the 1st trimester of pregnancy ( cause and value in determination of the age of the pregnancy ) ] . | NA | {
"id": "C0032979",
"name": "1st trimester",
"pos": [
46,
59
]
} | {
"id": "C0032961",
"name": "pregnancy",
"pos": [
126,
135
]
} |
the action of adrenaline , noradrenaline and acetylcholine on the pulmonary blood vessels : studies on the lung perfusion preparation of japanese toads . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
14,
24
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
27,
40
]
} |
[ effect of progesterone and of 6 alpha-methyl-17alpha-hydroxyprogesterone acetate on compensatory adrenal hypertrophy secondary to monolateral adrenalectomy in the rat ] . | NA | {
"id": "C0033308",
"name": "progesterone",
"pos": [
12,
24
]
} | {
"id": "C0020387",
"name": "17alpha-hydroxyprogesterone",
"pos": [
47,
74
]
} |
while it was observed that both botulinum toxin and albumin sedimented from lymph in glycerol gradient tubes to essentially the same level no evidence was developed to indicate association between toxin in lymph and serum albumin . | NA | {
"id": "C0001924",
"name": "albumin",
"pos": [
52,
59
]
} | {
"id": "C0036773",
"name": "serum albumin",
"pos": [
216,
229
]
} |
revised spectrophotometric methods for the determination of glutamic-oxalacetic transaminase , glutamic-pyruvic transaminase , and lactic acid dehydrogenase . | NA | {
"id": "C0002594",
"name": "transaminase",
"pos": [
80,
92
]
} | {
"id": "C0001899",
"name": "glutamic-pyruvic transaminase",
"pos": [
95,
124
]
} |
revised spectrophotometric methods for the determination of glutamic-oxalacetic transaminase , glutamic-pyruvic transaminase , and lactic acid dehydrogenase . | NA | {
"id": "C0002594",
"name": "transaminase",
"pos": [
80,
92
]
} | {
"id": "C0001899",
"name": "glutamic-pyruvic transaminase",
"pos": [
95,
124
]
} |
[ on proteins and their decomposition products . xvii . synthesis of the tri-and tetrapeptide derivatives of proline and hydroxyproline ] . | NA | {
"id": "C0033382",
"name": "proline",
"pos": [
109,
116
]
} | {
"id": "C0020388",
"name": "hydroxyproline",
"pos": [
121,
135
]
} |
[ changes in muscle and skin circulation after 1-adrenalin and 1-noradrenalin administration before and after prednisolone sodium succinate ] . | NA | {
"id": "C0014563",
"name": "adrenalin",
"pos": [
49,
58
]
} | {
"id": "C0028351",
"name": "noradrenalin",
"pos": [
65,
77
]
} |
gastric osmolar clearance and ionic barter : two mechanisms of electrolyte secretion by the human stomach . | NA | {
"id": "C0022023",
"name": "ionic",
"pos": [
30,
35
]
} | {
"id": "C0013832",
"name": "electrolyte",
"pos": [
63,
74
]
} |
the effect of nitrate and other anions on the mechanical response of single muscle fibres . | NA | {
"id": "C0028125",
"name": "nitrate",
"pos": [
14,
21
]
} | {
"id": "C0003075",
"name": "anions",
"pos": [
32,
38
]
} |
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