text
stringlengths 57
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| relation
stringclasses 125
values | h
dict | t
dict |
|---|---|---|---|
microbial diseases of the salivary glands with special reference to mumps and acute and chronic sialadenitis . | NA | {
"id": "C0036093",
"name": "diseases of the salivary glands",
"pos": [
10,
41
]
} | {
"id": "C0037023",
"name": "chronic sialadenitis",
"pos": [
88,
108
]
} |
[ contributions on biological chemistry . xx . distribution , excretion and metabolism of telodrin and heptachlor in rats and male rabbits , end product of heptachlor metabolism in warm blooded animals ] . | NA | {
"id": "C0221102",
"name": "excretion",
"pos": [
62,
71
]
} | {
"id": "C0025519",
"name": "metabolism",
"pos": [
167,
177
]
} |
in the anaesthetized cat the drug lowered the blood pressure and reduced the pressor response to adrenaline but not to noradrenaline . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
97,
107
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
119,
132
]
} |
adrenaline resembled phenylephrine more closely than it resembled isoprenaline , in that it showed more affinity for alpha-adrenoceptors , whereas noradrenaline , and the transmitter released on periarterial nerve stimulation , behaved more like isoprenaline , although both types of receptor were affected.4 . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
0,
10
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
147,
160
]
} |
plasma lipoproteins were separated into two fractions in the ultracentrifuge , and the lipids were extracted . | NA | {
"id": "C0023820",
"name": "lipoproteins",
"pos": [
7,
19
]
} | {
"id": "C0023779",
"name": "lipids",
"pos": [
87,
93
]
} |
when rabbit reticulocytes were incubated in normal blood plasma containing mevalonic acid-2- ( 14 ) c , radioactivity was incorporated into cholesterol , cholesteryl esters , and squalene in the cells . | NA | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
140,
151
]
} | {
"id": "C0008387",
"name": "cholesteryl esters",
"pos": [
154,
172
]
} |
total dna is composed of three components : a heavy satellite dna , a main dna of intermediate density , and a light satellite dna . | NA | {
"id": "C0012854",
"name": "dna",
"pos": [
6,
9
]
} | {
"id": "C0000702",
"name": "a",
"pos": [
129,
130
]
} |
total dna is composed of three components : a heavy satellite dna , a main dna of intermediate density , and a light satellite dna . | NA | {
"id": "C0012854",
"name": "dna",
"pos": [
6,
9
]
} | {
"id": "C0012934",
"name": "satellite dna",
"pos": [
117,
130
]
} |
under specified growth conditions , simian virus 40 encapsidated host dna in a noncircular form free of viral dna . | NA | {
"id": "C0012854",
"name": "dna",
"pos": [
70,
73
]
} | {
"id": "C0012939",
"name": "viral dna",
"pos": [
104,
113
]
} |
effects of hypophysectomy , methallibure , and thiourea on the ovary of the juvenile guppy , poecilia reticulata peters . | NA | {
"id": "C0025609",
"name": "methallibure",
"pos": [
28,
40
]
} | {
"id": "C0039958",
"name": "thiourea",
"pos": [
47,
55
]
} |
investigation shows that the enzyme first reversibly binds bromoacetyl-l-carnitine with an affinity similar to that shown for the normal substrate acetyl-l-carnitine ; | NA | {
"id": "C0087163",
"name": "l-carnitine",
"pos": [
71,
82
]
} | {
"id": "C0001040",
"name": "acetyl-l-carnitine",
"pos": [
147,
165
]
} |
the influence of environmental salinity on the prolactin- and gonadotropin-secreting regions in the pituitary of mugil ( teleostei ) . | NA | {
"id": "C0033371",
"name": "prolactin",
"pos": [
47,
56
]
} | {
"id": "C0018066",
"name": "gonadotropin",
"pos": [
62,
74
]
} |
stimulation of release and synthesis of growth hormone ( gh ) in tissue cultures of anterior pituitaries in response to gh-releasing hormone ( gh-rh ) . | NA | {
"id": "C0037663",
"name": "growth hormone",
"pos": [
40,
54
]
} | {
"id": "C0032016",
"name": "anterior pituitaries",
"pos": [
84,
104
]
} |
the enzymically modified bovine trna ( trnapcpcpa ) can bind labelled amino acids to form aminoacyl-trna , which can then transfer its labelled amino acids to growing polypeptide chains on ribosomes . | NA | {
"id": "C0035714",
"name": "aminoacyl-trna",
"pos": [
90,
104
]
} | {
"id": "C0002520",
"name": "amino acids",
"pos": [
144,
155
]
} |
an acidic lipid extract ( 0.165g ) obtained from 2kg of frozen rabbit kidney cortex was separated by silicic acid chromatography to yield eluates containing fatty acids , possible non-polar prostaglandin metabolites , pga , pge and pgf compounds . | NA | {
"id": "C0033554",
"name": "prostaglandin",
"pos": [
190,
203
]
} | {
"id": "C0033559",
"name": "pge",
"pos": [
224,
227
]
} |
with specific immunochemical techniques and polyacrylamide-gel electrophoresis it can be demonstrated that the very low density lipoproteins from all three sources contain the same major lipoprotein apoproteins . | NA | {
"id": "C0023825",
"name": "very low density lipoproteins",
"pos": [
111,
140
]
} | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
187,
198
]
} |
also the utilization of intracisternally injected tritiated norepinephrine was increased and was accompanied by a shift in the pattern of norepinephrine metabolism to normetanephrine . | NA | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
60,
74
]
} | {
"id": "C0028385",
"name": "normetanephrine",
"pos": [
167,
182
]
} |
bases , nucleosides , nucleotides , and polynucleotides were exposed to chemically generated singlet oxygen to determine whether the species oxidized paralleled those oxidized in photodynamic reactions . | NA | {
"id": "C0028630",
"name": "nucleotides",
"pos": [
22,
33
]
} | {
"id": "C0032550",
"name": "polynucleotides",
"pos": [
40,
55
]
} |
in neutral or basic aqueous solution guanine , guanosine , deoxyguanosine , guanylic acid , deoxyguanylic acid , thymine , and uracil reacted with singlet oxygen . | NA | {
"id": "C0040087",
"name": "thymine",
"pos": [
113,
120
]
} | {
"id": "C0041917",
"name": "uracil",
"pos": [
127,
133
]
} |
since the positronium formation rate in ice is considerably higher than it is in water , there should be a comparable increase in the positronium formation rate in muscle tissue if recent speculation that cellular water is ordered in a semicrystalline icelike state is correct . | NA | {
"id": "C0020746",
"name": "ice",
"pos": [
40,
43
]
} | {
"id": "C0043047",
"name": "water",
"pos": [
214,
219
]
} |
in laboratory experiments sterile males produced by crossing member species of the anopheles gambiae complex competed very successfully with normal males for normal females and the latter when mated with sterile males laid sterile eggs.a field trial was arranged in a small isolated village near bobo-dioulasso , upper volta ; | NA | {
"id": "C0021364",
"name": "sterile males",
"pos": [
26,
39
]
} | {
"id": "C0021359",
"name": "sterile",
"pos": [
223,
230
]
} |
the assay of carbenicillin in clinical specimens is complicated by the fact that carbenicillin also contains a small amount of benzylpenicillin , thereby precluding the use of conventional penicillin assay organisms . | NA | {
"id": "C0006976",
"name": "carbenicillin",
"pos": [
13,
26
]
} | {
"id": "C0030827",
"name": "benzylpenicillin",
"pos": [
127,
143
]
} |
catalytic effect of gssg on reduction of cytochrome c by gsh - possible model for facilitation of electron transfer and energy conservation by sulfonium ion formation . | NA | {
"id": "C0061516",
"name": "gssg",
"pos": [
20,
24
]
} | {
"id": "C0017817",
"name": "gsh",
"pos": [
57,
60
]
} |
a novel property of sulfate-utilizing revertants was their unselected ability to assimilate thiosulfate sulfur at 25 c but not at 37 c . | NA | {
"id": "C0038720",
"name": "sulfate",
"pos": [
20,
27
]
} | {
"id": "C0039950",
"name": "thiosulfate",
"pos": [
92,
103
]
} |
in addition , the beta-galactosidases from strains which form isoenzymes were more stable to heat and urea treatments than the enzyme formed by those organisms which produce reduced amounts of , or no , isoenzyme . | NA | {
"id": "C0014442",
"name": "enzyme",
"pos": [
65,
71
]
} | {
"id": "C0022173",
"name": "isoenzyme",
"pos": [
203,
212
]
} |
comparative study of the effects of porcine proinsulin and insulin on lipolysis and glucose oxidation in rat adipocytes . | NA | {
"id": "C0033362",
"name": "proinsulin",
"pos": [
44,
54
]
} | {
"id": "C0021641",
"name": "insulin",
"pos": [
59,
66
]
} |
examination of the substrate profile of a number of beta-lactamases synthesized by strains of pseudomonas aeruginosa has shown the presence of at least two distinct types of enzyme , one of which is more active against carbenicillin than against benzyl penicillin . | NA | {
"id": "C0006976",
"name": "carbenicillin",
"pos": [
219,
232
]
} | {
"id": "C0030827",
"name": "benzyl penicillin",
"pos": [
246,
263
]
} |
during amino acid starvation the ratio of putrescine concentration to spermidine concentration decreased in all strains , but it recovered afterward more rapidly in the third strain than in the other two . | NA | {
"id": "C0034170",
"name": "putrescine",
"pos": [
42,
52
]
} | {
"id": "C0037871",
"name": "concentration",
"pos": [
81,
94
]
} |
the lipid-depleted enzyme can be fully reactivated with external acyl coenzyme a , after which elongation with acetyl coenzyme a takes place . | NA | {
"id": "C0001374",
"name": "acyl coenzyme a",
"pos": [
65,
80
]
} | {
"id": "C0001026",
"name": "acetyl",
"pos": [
111,
117
]
} |
during the period between 20 and 24 hr after infection of kb cells with type 5 adenovirus , at a time when approximately 85 % of the proteins made were virus-specific , viral proteins were synthesized on polyribosomes with an average sedimentation coefficient of 200s . | NA | {
"id": "C0033684",
"name": "proteins",
"pos": [
133,
141
]
} | {
"id": "C0042736",
"name": "viral proteins",
"pos": [
169,
183
]
} |
[ orthostatic electrocardiogram in arrhythmia , with special reference to conduction disorders , heterotopic rhythm and sinus arrhythmia ] . | NA | {
"id": "C0003811",
"name": "arrhythmia",
"pos": [
35,
45
]
} | {
"id": "C0003813",
"name": "sinus arrhythmia",
"pos": [
120,
136
]
} |
effects of adrenaline and noradrenaline on euglobulin lysis time and effects of adrenergic receptor blocking agents on shortening of lysis time by adrenaline . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
26,
39
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
147,
157
]
} |
[ effect of tetracycline base , tetracycline hydrochloride and oxytetracycline base on developmental changes in metatarsal bones of extremities of rat fetuses ] . | NA | {
"id": "C0039644",
"name": "tetracycline",
"pos": [
12,
24
]
} | {
"id": "C0546879",
"name": "tetracycline hydrochloride",
"pos": [
32,
58
]
} |
studies on adrenal steroid hydroxylases : optical absorption spectroscopy of adrenal iron-sulfur protein ( adrenodoxin ) and its apoprotein . | NA | {
"id": "C0022095",
"name": "iron-sulfur protein",
"pos": [
85,
104
]
} | {
"id": "C0001657",
"name": "adrenodoxin",
"pos": [
107,
118
]
} |
evidence for the formation of the cytotoxic aldehyde acrolein from enzymatically oxidized spermine or spermidine . | NA | {
"id": "C0001992",
"name": "aldehyde",
"pos": [
44,
52
]
} | {
"id": "C0001204",
"name": "acrolein",
"pos": [
53,
61
]
} |
[ studies on the determination methods with polyaldehydes . xi . fluorometric determination of o-phenylenediamine in the presence of m- and p-phenylenediamine ] . | NA | {
"id": "C0031468",
"name": "phenylenediamine",
"pos": [
97,
113
]
} | {
"id": "C0048678",
"name": "p-phenylenediamine",
"pos": [
140,
158
]
} |
[ current aspects of cutaneous tuberculosis , with an evaluation of the cologne lupus registration file from the years 1953-58 and 1963-68 ] . | NA | {
"id": "C0041309",
"name": "of cutaneous tuberculosis",
"pos": [
18,
43
]
} | {
"id": "C0024131",
"name": "lupus",
"pos": [
80,
85
]
} |
assymetry in the distribution of basic amino acid residues in the moderately lysine-rich histone f2b from calf thymus . | NA | {
"id": "C0301714",
"name": "basic amino acid",
"pos": [
33,
49
]
} | {
"id": "C0024337",
"name": "lysine",
"pos": [
77,
83
]
} |
occurrence of adrenaline and noradrenaline cells in the adrenal gland of the gentoo penguin ( pygoscelis papua ) . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
14,
24
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
29,
42
]
} |
[ flavonol glycosides of euphorbia amygdaloides and their quantitative determination at various stages of plant development . 5. flavonoids of native euphorbiaceae ] . | NA | {
"id": "C0060444",
"name": "flavonol",
"pos": [
2,
10
]
} | {
"id": "C0596577",
"name": "flavonoids",
"pos": [
129,
139
]
} |
most of the childhood urinary infections in this practice occurred before the age of 5 years , and the incidence of significant bacteriuria in this age group was 4.9 % per annum . | NA | {
"id": "C0042029",
"name": "of",
"pos": [
5,
7
]
} | {
"id": "C0004659",
"name": "bacteriuria",
"pos": [
128,
139
]
} |
the reaction of 5-bromouracil derivatives with sulfur nucleophiles , and a novel synthetic route to 5-sulfur-substituted uracils and nucleotides . | NA | {
"id": "C0006242",
"name": "bromouracil",
"pos": [
18,
29
]
} | {
"id": "C0041917",
"name": "uracils",
"pos": [
121,
128
]
} |
renal tubular absorption of proline , hydroxyproline , and glycine by the newborn of most mammals is inefficient compared to that of the adult . | NA | {
"id": "C0033382",
"name": "proline",
"pos": [
28,
35
]
} | {
"id": "C0020388",
"name": "hydroxyproline",
"pos": [
38,
52
]
} |
dna preparations from seven bacterial species and from e. coli phage t4 , and also the complementary l and h fractions into which these dna specimens , after denaturation , were separated by chromatography on methylated albumin-kieselguhr columns , were studied as templates in the rna polymerase system , and the nucleotide composition of the rna products was determined . | NA | {
"id": "C0012924",
"name": "dna",
"pos": [
0,
3
]
} | {
"id": "C0012854",
"name": "dna",
"pos": [
136,
139
]
} |
this model predicts that during the noninducible period , g2 , the tyrosine aminotransferase repressor would not be present and thus tyrosine aminotransferase synthesis would be constitutive . | NA | {
"id": "C0041487",
"name": "tyrosine aminotransferase",
"pos": [
67,
92
]
} | {
"id": "C0002594",
"name": "aminotransferase",
"pos": [
142,
158
]
} |
cells transformed by the oncogenic virus sv40 are known to contain viral dna integrated into cellular dna and to produce virus-specific rna . | NA | {
"id": "C0012939",
"name": "viral dna",
"pos": [
67,
76
]
} | {
"id": "C0012854",
"name": "dna",
"pos": [
102,
105
]
} |
the kinetics of accumulation of the known stable rna species ( 23s , 16s , and 5s rrna and trna ) in escherichia coli c122 were monitored by polyacrylamide gel electrophoresis of purified cellular rna , following termination of brief pulse labeling with ( 32 ) p-orthophosphate . | NA | {
"id": "C0035701",
"name": "rrna",
"pos": [
82,
86
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
197,
200
]
} |
cell-bound isozymes of penicillinase are distinguished from extracellular enzyme by their capacity to bind deoxycholate and to elute with an apparent molecular weight of 45,000 on gel filtration in its presence . | NA | {
"id": "C0022173",
"name": "isozymes",
"pos": [
11,
19
]
} | {
"id": "C0014442",
"name": "enzyme",
"pos": [
74,
80
]
} |
mechanism of the renal tubular transport of morphine and morphine ethereal sulfate in the chicken . | NA | {
"id": "C0026549",
"name": "morphine",
"pos": [
44,
52
]
} | {
"id": "C0066814",
"name": "morphine",
"pos": [
57,
65
]
} |
the specific radioactivity of each individual cholesteryl ester was then determined for each sample , by separately measuring the distribution of cholesterol mass and of radioactivity among four different cholesteryl ester groups , namely the saturated , mono- , di- , and tetra-unsaturated esters . | NA | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
146,
157
]
} | {
"id": "C0008387",
"name": "cholesteryl ester",
"pos": [
205,
222
]
} |
the triether appears to be an ideal nonabsorbable oil-phase marker for use in lipid absorption studies . | NA | {
"id": "C0028908",
"name": "oil",
"pos": [
50,
53
]
} | {
"id": "C0023779",
"name": "lipid",
"pos": [
78,
83
]
} |
triether may be of value for studying the absorption of compounds present predominantly in the oil phase during digestion and may have significant advantages over other proposed lipid markers . | NA | {
"id": "C0028908",
"name": "oil",
"pos": [
95,
98
]
} | {
"id": "C0023779",
"name": "lipid",
"pos": [
178,
183
]
} |
the mobilization of free fatty acids in relation to adipose tissue triglyceride fatty acids in the rat . | NA | {
"id": "C0015688",
"name": "free fatty acids",
"pos": [
20,
36
]
} | {
"id": "C0015684",
"name": "fatty acids",
"pos": [
80,
91
]
} |
in cats anaesthetized with pentobarbitone sodium , infusions of adrenaline , noradrenaline ( 0.5 mug/kg per min ) and isoprenaline ( 0.25 mug/kg per min ) increased myocardial blood flow , myocardial heat production , left ventricular systolic and end-diastolic pressures , left ventricular +ve and -ve dp/dt max , and calculated cardiac output , effort and oxygen consumption . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
64,
74
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
77,
90
]
} |
after alprenolol the effects of adrenaline and noradrenaline were potentiated and that of isoprenaline abolished ; | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
32,
42
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
47,
60
]
} |
alprenolol did not influence the increases in arterial systolic pressure which followed the administration of adrenaline and noradrenaline.3 . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
110,
120
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
125,
138
]
} |
increases in liver and myocardial blood flow and heat production produced by noradrenaline , adrenaline and isoprenaline were reduced after alprenolol.7 . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
77,
90
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
93,
103
]
} |
rises in serum conjugated bilirubin following infusion of bilirubin were produced by 17alpha-ethinyloestradiol and mestranol but not by the progestogens . | NA | {
"id": "C0015011",
"name": "ethinyloestradiol",
"pos": [
93,
110
]
} | {
"id": "C0025506",
"name": "mestranol",
"pos": [
115,
124
]
} |
the purpose of this study was to determine the effect of familial hyperlipoproteinemia ( hlp ) on peripheral vascular disease ( pvd ) and the extent to which the vascular disease ( pvd ) and the extent to which the vascular disease is modified by treatment of the lipoprotein disorder . | NA | {
"id": "C0085096",
"name": "pvd",
"pos": [
128,
131
]
} | {
"id": "C0042373",
"name": "vascular disease",
"pos": [
215,
231
]
} |
studies with cholinesterase inhibitors and specific substrates indicated that about 90 % of cholinesterase of human motor endplates is acetylcholinesterase , and about 10 % is pseudocholinesterase . | NA | {
"id": "C0001044",
"name": "acetylcholinesterase",
"pos": [
135,
155
]
} | {
"id": "C0008429",
"name": "pseudocholinesterase",
"pos": [
176,
196
]
} |
the mechanism of accelerated uric acid formation in these patients was explored by measuring the incorporation of glycine- ( 14 ) c into various urinary purine bases of normal and enzyme-deficient subjects during treatment with the xanthine oxidase inhibitor , allopurinol . | NA | {
"id": "C0034140",
"name": "purine",
"pos": [
153,
159
]
} | {
"id": "C0002144",
"name": "allopurinol",
"pos": [
261,
272
]
} |
in the presence of normal hg-prtase activity , allopurinol reduced purine biosynthesis as demonstrated by diminished excretion of total urinary purine or by reduction of glycine- ( 14 ) c incorporation into hypoxanthine , xanthine , and uric acid to less than one-half of control values . | NA | {
"id": "C0002144",
"name": "allopurinol",
"pos": [
47,
58
]
} | {
"id": "C0034140",
"name": "purine",
"pos": [
144,
150
]
} |
the recently discovered hormone precursors , pork and beef proinsulins , their respective connecting peptides , and beef proinsulin intermediates have been compared to insulin in their ability to stimulate the conversion of glucose-u- ( 14 ) c to ( 14 ) co ( 2 ) and lipids in isolated fat cells . | NA | {
"id": "C0006558",
"name": "connecting peptides",
"pos": [
90,
109
]
} | {
"id": "C0033362",
"name": "proinsulin",
"pos": [
121,
131
]
} |
the recently discovered hormone precursors , pork and beef proinsulins , their respective connecting peptides , and beef proinsulin intermediates have been compared to insulin in their ability to stimulate the conversion of glucose-u- ( 14 ) c to ( 14 ) co ( 2 ) and lipids in isolated fat cells . | NA | {
"id": "C0033362",
"name": "proinsulin",
"pos": [
59,
69
]
} | {
"id": "C0021641",
"name": "insulin",
"pos": [
168,
175
]
} |
the concentrations of beef and pork proinsulins required to achieve the same biological effect were respectively , 15 and 10 times that of insulin . | NA | {
"id": "C0033362",
"name": "proinsulins",
"pos": [
36,
47
]
} | {
"id": "C0021641",
"name": "insulin",
"pos": [
139,
146
]
} |
beef proinsulin intermediates required only 2.6 times the concentration of insulin for the same effect . | NA | {
"id": "C0033362",
"name": "proinsulin",
"pos": [
5,
15
]
} | {
"id": "C0021641",
"name": "insulin",
"pos": [
75,
82
]
} |
pork and beef connecting peptides in high or low concentrations alone or in combination with proinsulin , insulin , or proinsulin intermediates showed no biological effect on the isolated fat cell system . | NA | {
"id": "C0006558",
"name": "connecting peptides",
"pos": [
14,
33
]
} | {
"id": "C0033362",
"name": "proinsulin",
"pos": [
119,
129
]
} |
pork and beef connecting peptides in high or low concentrations alone or in combination with proinsulin , insulin , or proinsulin intermediates showed no biological effect on the isolated fat cell system . | NA | {
"id": "C0021641",
"name": "insulin",
"pos": [
96,
103
]
} | {
"id": "C0033362",
"name": "proinsulin",
"pos": [
119,
129
]
} |
beef proinsulin intermediates , on the other hand , were found to react with the pork insulin antiserum to an extent nearly equal to that of insulin . | NA | {
"id": "C0033362",
"name": "proinsulin",
"pos": [
5,
15
]
} | {
"id": "C0021641",
"name": "insulin",
"pos": [
141,
148
]
} |
these data suggest that ( a ) proinsulin exhibits its effect on the isolated fat cells independent of its conversion to insulin , ( b ) connecting peptides have no biological effect under present experimental conditions , and ( c ) in comparison to insulin , immunological reactivity of proinsulin is greater than its biological activity using our pork insulin antiserum ; | NA | {
"id": "C0021641",
"name": "insulin",
"pos": [
33,
40
]
} | {
"id": "C0033362",
"name": "proinsulin",
"pos": [
287,
297
]
} |
blood acetaldehyde concentrations ranged from 0.11 to 0.15 and from 0.04 to 0.08 milligrams per 100 milliliters when blood ethanol concentrations ranged from 1 to 400 milligrams per 100 milliliters after consumption of bourbon or grain ethanol , respectively . | NA | {
"id": "C0684262",
"name": "blood ethanol concentrations",
"pos": [
117,
145
]
} | {
"id": "C0001962",
"name": "ethanol",
"pos": [
236,
243
]
} |
intraventricular infusions of adrenaline and noradrenaline had no effect on the level of prostaglandin release.3 . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
30,
40
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
45,
58
]
} |
when prostaglandin e ( 1 ) was added to the fluid perfusing the ventricular system , respiratory changes were observed but almost all the added prostaglandin was recovered from the perfusate leaving the cisterna . | NA | {
"id": "C0033559",
"name": "prostaglandin e",
"pos": [
5,
20
]
} | {
"id": "C0033554",
"name": "prostaglandin",
"pos": [
144,
157
]
} |
the antagonism of adrenergic neurone blockade by amphetamine and dexamphetamine in the rat and guinea-pig . | NA | {
"id": "C0002658",
"name": "amphetamine",
"pos": [
49,
60
]
} | {
"id": "C0011812",
"name": "dexamphetamine",
"pos": [
65,
79
]
} |
in all hearts except the toad , cocaine was an effective blocking agent for the uptake of ( +/- ) - ( 3 ) h-noradrenaline and led to an increase in ( 3 ) h-normetanephrine in these hearts . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
108,
121
]
} | {
"id": "C0028385",
"name": "normetanephrine",
"pos": [
156,
171
]
} |
the present necropsy study shows an oriental pattern of gallstone disease in singapore , namely , a relatively low overall frequency , an equal involvement of both sexes , a high proportion of pigment stones , and the common occurrence of choledocholithiasis associated with pyogenic cholangitis . | NA | {
"id": "C0008350",
"name": "gallstone",
"pos": [
56,
65
]
} | {
"id": "C0701818",
"name": "choledocholithiasis",
"pos": [
239,
258
]
} |
reported birth weights and growth rates in a group of patients with primary anorexia nervosa ( weight phobia ) . | NA | {
"id": "C0005612",
"name": "birth weights",
"pos": [
9,
22
]
} | {
"id": "C0005910",
"name": "weight",
"pos": [
95,
101
]
} |
in both def and cef cultures , cells containing immunofluorescent ( if ) antigen also contained herpesvirus particles ; | NA | {
"id": "C0016030",
"name": "cef",
"pos": [
16,
19
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
31,
36
]
} |
escherichia coli strain 15 tau , which requires thymine , arginine , and uracil for growth and harbors an apparently defective prophage , was induced by exposure to ultraviolet light ( 580 ergs/mm ( 2 ) ) or to mitomycin c ( 5 mug/ml ) . | NA | {
"id": "C0040087",
"name": "thymine",
"pos": [
48,
55
]
} | {
"id": "C0041917",
"name": "uracil",
"pos": [
73,
79
]
} |
[ effect of oleandomycin in triacetyloleandomycin on the result of determination of biological activity of the latter by agar diffusion method ] . | NA | {
"id": "C0028923",
"name": "oleandomycin",
"pos": [
12,
24
]
} | {
"id": "C0041165",
"name": "triacetyloleandomycin",
"pos": [
28,
49
]
} |
iron concentratio n bal ganglia and cerebral cortex obtained by overloading rabbits and monkeys with iron dextran . | NA | {
"id": "C0302583",
"name": "iron",
"pos": [
0,
4
]
} | {
"id": "C0022092",
"name": "iron dextran",
"pos": [
101,
113
]
} |
native ribosomal rna anid inttact pliage r17 rna are insensitive to attack by ribonuclease v , an exonucleolytic activity associated with ribosome movement on the substrate rna . | NA | {
"id": "C0035701",
"name": "ribosomal rna",
"pos": [
7,
20
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
173,
176
]
} |
however , ribosomal rna becomes a substrate when it is heated under conditions that make it a template for protein synthesis , and r17 rna is attacked if it is either heated or fragmnented . | NA | {
"id": "C0035701",
"name": "ribosomal rna",
"pos": [
10,
23
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
135,
138
]
} |
comparison of this estimate of the potential with the patient 's vision after cataract extraction shows that this test can indicate the condition of the fovea behind a cataract . | NA | {
"id": "C1306068",
"name": "after cataract",
"pos": [
72,
86
]
} | {
"id": "C0086543",
"name": "cataract",
"pos": [
168,
176
]
} |
the effect of a high dose of adrenalin and noradrenalin upon visual evoked response ( ver ) and electroretinogram ( erg ) . | NA | {
"id": "C0014563",
"name": "adrenalin",
"pos": [
29,
38
]
} | {
"id": "C0028351",
"name": "noradrenalin",
"pos": [
43,
55
]
} |
[ regularities in absorption and distribution of polysynthetic penicillins -- methicillin and oxacillin in patients with chronic renal insufficiency ] . | NA | {
"id": "C0030842",
"name": "penicillins",
"pos": [
63,
74
]
} | {
"id": "C0025643",
"name": "methicillin",
"pos": [
78,
89
]
} |
[ regularities in absorption and distribution of polysynthetic penicillins -- methicillin and oxacillin in patients with chronic renal insufficiency ] . | NA | {
"id": "C0030842",
"name": "penicillins",
"pos": [
63,
74
]
} | {
"id": "C0029983",
"name": "oxacillin",
"pos": [
94,
103
]
} |
five male baboons were fed cholesterol-1alpha- ( 3 ) h until an isotopic steady state was approached in which the ratio of serum to dietary cholesterol specific activity was constant . | NA | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
27,
38
]
} | {
"id": "C0008395",
"name": "dietary cholesterol",
"pos": [
132,
151
]
} |
after administration of proline- ( 14 ) c to patients with paget 's disease hydroxyproline- ( 14 ) c was excreted in the urine . | NA | {
"id": "C0033382",
"name": "proline",
"pos": [
24,
31
]
} | {
"id": "C0020388",
"name": "hydroxyproline",
"pos": [
76,
90
]
} |
the main increases of total amount , labeling , and specific activity of lipid and protein occurred in the d < 1.019 lipoprotein fraction . | NA | {
"id": "C0023779",
"name": "lipid",
"pos": [
73,
78
]
} | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
117,
128
]
} |
blocking of lipoprotein and chylomicron removal with triton did not prevent the action of ethanol on serum lipids , indicating that the ethanol effect is not likely due to defective removal of lipids from the circulation . | NA | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
12,
23
]
} | {
"id": "C0008731",
"name": "chylomicron",
"pos": [
28,
39
]
} |
blocking of lipoprotein and chylomicron removal with triton did not prevent the action of ethanol on serum lipids , indicating that the ethanol effect is not likely due to defective removal of lipids from the circulation . | NA | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
12,
23
]
} | {
"id": "C0023779",
"name": "lipids",
"pos": [
193,
199
]
} |
the dna of the colicinogenic proteus has been shown to contain a small amount of a satellite dna which presumably harbors the col k factor . | NA | {
"id": "C0012854",
"name": "dna",
"pos": [
4,
7
]
} | {
"id": "C0012934",
"name": "satellite dna",
"pos": [
83,
96
]
} |
virus multiplication is inhibited in chick allantoic cells by lower concentrations than those required to inhibit virus growth in chick embryo fibroblasts . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
53,
58
]
} | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
143,
154
]
} |
a high prevalence of ischaemic heart disease was found in these patients at the time of diagnosis , and this finding had some predictive value as regards prognosis over the three-year period.a comparative study with general medical outpatients and long-established diabetics ( greater than 10 years ' duration of disease ) confirmed the high prevalence of ischaemic heart disease in late-onset mild diabetics controlled by diet or oral drugs . | NA | {
"id": "C0018799",
"name": "of",
"pos": [
18,
20
]
} | {
"id": "C0151744",
"name": "the",
"pos": [
333,
336
]
} |
no significant differences could be detected between sequential and combined preparations containing the same doses of oestrogen , nor between the two oestrogens , ethinyloestradiol and mestranol . | NA | {
"id": "C0015011",
"name": "ethinyloestradiol",
"pos": [
164,
181
]
} | {
"id": "C0025506",
"name": "mestranol",
"pos": [
186,
195
]
} |
thus there was a significant deficit of reports associated with the combination of mestranol 100 mug . with norethynodrel 2.5 mg. and a significant excess of reports associated with the combination of ethinyloestradiol 50 mug . with megestrol acetate 4 mg . | NA | {
"id": "C0025506",
"name": "mestranol",
"pos": [
83,
92
]
} | {
"id": "C0015011",
"name": "ethinyloestradiol",
"pos": [
201,
218
]
} |
[ intraoperative radiotherapy of abdominal tumors . 3. intraoperative irradiation to carcinoma of the colon and retroperitoneal tumors ] . | NA | {
"id": "C0000735",
"name": "abdominal tumors",
"pos": [
33,
49
]
} | {
"id": "C0035358",
"name": "retroperitoneal tumors",
"pos": [
112,
134
]
} |
a simple and rapid acrylamide gel method for estimating the molecular weights of proteins and protein subunits . | NA | {
"id": "C0033684",
"name": "proteins",
"pos": [
81,
89
]
} | {
"id": "C0599220",
"name": "protein subunits",
"pos": [
94,
110
]
} |
[ effect of alloxan , vitamin c and dehydroascorbic acid on in vitro biosynthesis of fatty acids in the blood ] . | NA | {
"id": "C0003968",
"name": "vitamin c",
"pos": [
22,
31
]
} | {
"id": "C0011177",
"name": "dehydroascorbic acid",
"pos": [
36,
56
]
} |
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