text
stringlengths 57
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| relation
stringclasses 125
values | h
dict | t
dict |
---|---|---|---|
it was shown that the cells bound about the same amount of lectin at 0 and 37 degrees c , but less protein was bound at 25 degrees c . | NA | {
"id": "C0023206",
"name": "lectin",
"pos": [
59,
65
]
} | {
"id": "C0033684",
"name": "protein",
"pos": [
99,
106
]
} |
these same effects of the blocking agents were observed when adrenaline was used instead of na . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
61,
71
]
} | {
"id": "C0028351",
"name": "na",
"pos": [
92,
94
]
} |
temperature recordings in vivo revealed , in fact , that the tissue was maintained at a temperature close to that of the body core during immersion of the pups in ice-water . | NA | {
"id": "C0020746",
"name": "ice",
"pos": [
163,
166
]
} | {
"id": "C0043047",
"name": "water",
"pos": [
167,
172
]
} |
beta-adrenergic blockade markedly increased the cooling rates at both locations in ice-water , while curarization , accompanied by artificial respiration did not . | NA | {
"id": "C0020746",
"name": "ice",
"pos": [
83,
86
]
} | {
"id": "C0043047",
"name": "water",
"pos": [
87,
92
]
} |
the results of bone scanning with the newer technetium-99m complexes were correlated with clinical , laboratory , and radiographic findings in 26 patients with malignant lymphoma ( 10 with hodgkin 's disease and 16 with non-hodgkin 's lymphomas ) . | NA | {
"id": "C0024299",
"name": "malignant lymphoma",
"pos": [
160,
178
]
} | {
"id": "C0019829",
"name": "hodgkin 's disease",
"pos": [
189,
207
]
} |
the results of bone scanning with the newer technetium-99m complexes were correlated with clinical , laboratory , and radiographic findings in 26 patients with malignant lymphoma ( 10 with hodgkin 's disease and 16 with non-hodgkin 's lymphomas ) . | NA | {
"id": "C0024299",
"name": "malignant lymphoma",
"pos": [
160,
178
]
} | {
"id": "C0024305",
"name": "non-hodgkin 's",
"pos": [
220,
234
]
} |
the literature is reviewed regarding the incidence of prominent lymphadenopathy and chromosome abnormalities in agnogenic myeloid metaplasia and other myeloproliferative disorders . | NA | {
"id": "C0001815",
"name": "agnogenic myeloid metaplasia",
"pos": [
112,
140
]
} | {
"id": "C0027022",
"name": "myeloproliferative disorders",
"pos": [
151,
179
]
} |
this is not due to detectable alterations in the ability of the glucocorticoid receptor to bind the steroid hormone , or of the hormone-receptor complex to undergo activation , or of the activated steroid-receptor complex to bind to nuclei derived from the hepatoma or normal liver . | NA | {
"id": "C0034809",
"name": "glucocorticoid receptor",
"pos": [
64,
87
]
} | {
"id": "C0034840",
"name": "steroid-receptor",
"pos": [
197,
213
]
} |
this biphasic effect , which was less prominent in human fibroblasts , may reflect a selective sensitivity either of part of the cell population or of part of the dna within individual cells . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
57,
68
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
185,
190
]
} |
the production and repair of dna single-strand breaks after bleomycin treatment were the same in normal human and xeroderma pigmentosum fibroblasts , indicating that these events do not require the excision endonuclease that appears to be defective in these ultraviolet light-sensitive xeroderma cells . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
136,
147
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
296,
301
]
} |
studies of ischaemic myocardium following occlusion of coronary arterial branches revealed a substantial decline in creatine phosphate , adenosine triphosphate , and total adenine nucleotide contents over 40 min . | NA | {
"id": "C0001480",
"name": "adenosine",
"pos": [
137,
146
]
} | {
"id": "C0001413",
"name": "adenine nucleotide",
"pos": [
172,
190
]
} |
for the nuclear rnas , melting curve , density , and size determinations on the hybrids confirmed the presence of an rna species indistinguishable by cdna hybridization from reticulocyte globin mrna . | NA | {
"id": "C0035700",
"name": "nuclear rnas",
"pos": [
8,
20
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
195,
198
]
} |
the proportion of the globin rna sequences in the nuclear rna that are found associated with poly ( a ) sequences does not vary markedly from one tissue or cell line to another . | NA | {
"id": "C0035668",
"name": "rna",
"pos": [
29,
32
]
} | {
"id": "C0035700",
"name": "nuclear rna",
"pos": [
50,
61
]
} |
both the kinetics of entry of labeled 75s rna into the cytoplasm-that is , a constant rate of increase after a brief lag-and chase data are incompatible with a precursor-product relationship between the great majority of nuclear 75s rna and cytoplasmic 75s rna with messenger characteristics . | NA | {
"id": "C0035668",
"name": "rna",
"pos": [
42,
45
]
} | {
"id": "C0035700",
"name": "nuclear",
"pos": [
221,
228
]
} |
one antiserum contained antibodies that reacted with these dna-binding proteins , while the second antiserum did not contain detectable levels of antibody . | NA | {
"id": "C0003241",
"name": "antibodies",
"pos": [
24,
34
]
} | {
"id": "C0020960",
"name": "antiserum",
"pos": [
99,
108
]
} |
the dimer linkage dissociates at temperature estimated to be 87 degrees c in aqueous 0.1m na+ for rd-114 and baboon viral rnas , but at the lower temperature of 66 degrees c for woolly monkey rna . | NA | {
"id": "C0035736",
"name": "viral rnas",
"pos": [
116,
126
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
192,
195
]
} |
from an examination of the kinetics of digestion of h3/h4 reconstitutes , we conclude that although the other histones have a role in dna organization within the nucleosome , the arginine-rich histone pair , h3/h4 , can organize dna segments the length of the nucleosome core in the absence of all other histones . | NA | {
"id": "C0000702",
"name": "a",
"pos": [
5,
6
]
} | {
"id": "C0012854",
"name": "dna",
"pos": [
229,
232
]
} |
one of the membrane proteins iodinated has been shown to be myosin as follows : it has the same electrophoretic mobility ( molecular weight 200,000 daltons ) as myosin heavy chain on sodium dodecylsulfate polyacrylamide gels and the labeled myosin is specifically precipitated by fibroblast myosin antiserum from a preparation of purified plasma membrane that have been solubilized by treatment with 1 % triton x-100 . | NA | {
"id": "C0027100",
"name": "myosin",
"pos": [
60,
66
]
} | {
"id": "C0027096",
"name": "myosin",
"pos": [
291,
297
]
} |
in the normal fibroblasts , the binding of insulin was low in growing cells and increased 2-9 fold in confluent stationary cells . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
14,
25
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
123,
128
]
} |
since the location of the ecori sites in rdna is known , and the specificity of the two exonucleases for 5 ' and 3 ' ends of dna strands has been established , the hybridization of the different partially digested rdna fragments with either 18s or 28s rrna could be interpreted in terms of polarity of the coding strand of rdna , and consequently of the rna ( see models in figure 1 ) . | NA | {
"id": "C0012933",
"name": "rdna",
"pos": [
41,
45
]
} | {
"id": "C0012854",
"name": "dna",
"pos": [
324,
327
]
} |
since the location of the ecori sites in rdna is known , and the specificity of the two exonucleases for 5 ' and 3 ' ends of dna strands has been established , the hybridization of the different partially digested rdna fragments with either 18s or 28s rrna could be interpreted in terms of polarity of the coding strand of rdna , and consequently of the rna ( see models in figure 1 ) . | NA | {
"id": "C0035701",
"name": "rrna",
"pos": [
252,
256
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
354,
357
]
} |
comparison of the microsome catalysed hydrocarbon-deoxyribonucleoside products with those obtained by reaction with dna of 7meba-5,6-oxide suggested that this k-region epoxide made a significant contribution to the liver microsome-induced dna binding . | NA | {
"id": "C0012854",
"name": "dna",
"pos": [
116,
119
]
} | {
"id": "C0000702",
"name": "a",
"pos": [
241,
242
]
} |
as the oxidized bis ( gs ) -dmap was bound to hemoglobin more slowly and to a lesser extent , it produced more ferrihemoglobin than dmap . | NA | {
"id": "C0019046",
"name": "hemoglobin",
"pos": [
46,
56
]
} | {
"id": "C0025635",
"name": "ferrihemoglobin",
"pos": [
111,
126
]
} |
in contrast to the reactions of dmap with hemoglobin , hydrogen peroxide and superoxide radicals are involved in the ferrihemoglobin formation by bis ( gs ) -dmap . | NA | {
"id": "C0019046",
"name": "hemoglobin",
"pos": [
42,
52
]
} | {
"id": "C0025635",
"name": "ferrihemoglobin",
"pos": [
117,
132
]
} |
a significant weight increase of the glands is observed while norepinephrine and epinephrine content is depleted after dichlorvos intoxication . | NA | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
62,
76
]
} | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
81,
92
]
} |
v.s.v . induced polycaryocytes in rat embryonic fibroblasts , transformed by the prague strain of sarcoma rous ( xc cells ) . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
48,
59
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
116,
121
]
} |
the transcapillary escape rate of albumin ( teralb ) , i.e. , the fraction of intravascular mass of albumin that passes to the extravascular space per unit of time , was determined from the disappearance of intravenously injected 125i-labeled human serum albumin during the first 60 minutes after injection in 10 subjects with chronic right heart failure . | NA | {
"id": "C0001924",
"name": "albumin",
"pos": [
34,
41
]
} | {
"id": "C0304925",
"name": "human serum albumin",
"pos": [
243,
262
]
} |
consistent with reported observations that ouabain-binding , metabolism , and excretion do not change with age , we found no significant differences in the transfer coefficients in a linear two-compartment open model for ouabain pharmacokinetics following a bolus of 0.05 mg/kg . | NA | {
"id": "C0025519",
"name": "metabolism",
"pos": [
61,
71
]
} | {
"id": "C0221102",
"name": "excretion",
"pos": [
78,
87
]
} |
at least 15 dipeptides were identified in the urine , most of which contained proline or hydroxyproline in the carboxy terminal position . | NA | {
"id": "C0033382",
"name": "proline",
"pos": [
78,
85
]
} | {
"id": "C0020388",
"name": "hydroxyproline",
"pos": [
89,
103
]
} |
hyperuricaemia and hyperlipidaemia ( elevated fasting plasma cholesterol or triglycerides ) were frequently found in 219 males and 63 females with peripheral vascular disease ( pvd ) . | NA | {
"id": "C0020473",
"name": "hyperlipidaemia",
"pos": [
19,
34
]
} | {
"id": "C0020443",
"name": "elevated",
"pos": [
37,
45
]
} |
response of plasma testosterone , urinary 17-oxosteroids , oestrogens , and androsterone plus aetiocholanolone to human chorionic gonadotrophin in dexamethasone-suppressed men . | NA | {
"id": "C0000167",
"name": "17-oxosteroids",
"pos": [
42,
56
]
} | {
"id": "C0002865",
"name": "androsterone",
"pos": [
76,
88
]
} |
response of plasma testosterone , urinary 17-oxosteroids , oestrogens , and androsterone plus aetiocholanolone to human chorionic gonadotrophin in dexamethasone-suppressed men . | NA | {
"id": "C0000167",
"name": "17-oxosteroids",
"pos": [
42,
56
]
} | {
"id": "C0015124",
"name": "aetiocholanolone",
"pos": [
94,
110
]
} |
the administration of human chorionic gonadotrophin ( hcg ) to dexamethasone-suppressed men caused parallel changes in the concentration of plasma testosterone and in the urinary output of androsterone+aetiocholanolone , total 17-oxosteroids and oestrogens . | NA | {
"id": "C0002865",
"name": "androsterone",
"pos": [
189,
201
]
} | {
"id": "C0000167",
"name": "17-oxosteroids",
"pos": [
227,
241
]
} |
the administration of human chorionic gonadotrophin ( hcg ) to dexamethasone-suppressed men caused parallel changes in the concentration of plasma testosterone and in the urinary output of androsterone+aetiocholanolone , total 17-oxosteroids and oestrogens . | NA | {
"id": "C0015124",
"name": "aetiocholanolone",
"pos": [
202,
218
]
} | {
"id": "C0000167",
"name": "17-oxosteroids",
"pos": [
227,
241
]
} |
with these exceptions , the response to hcg could by followed as well by measuring androsterone+aetiocholanolone , 17-oxosteroid or oestrogen excretion rates as by following plasma testosterone levels . | NA | {
"id": "C0002865",
"name": "androsterone",
"pos": [
83,
95
]
} | {
"id": "C0000167",
"name": "17-oxosteroid",
"pos": [
115,
128
]
} |
with these exceptions , the response to hcg could by followed as well by measuring androsterone+aetiocholanolone , 17-oxosteroid or oestrogen excretion rates as by following plasma testosterone levels . | NA | {
"id": "C0015124",
"name": "aetiocholanolone",
"pos": [
96,
112
]
} | {
"id": "C0000167",
"name": "17-oxosteroid",
"pos": [
115,
128
]
} |
fibroblast cultures differed from the lymphocytes : in the former the majority of the cells lacked the abnormal y-chromosome , their karyotype being 45 , x0 . | NA | {
"id": "C0016030",
"name": "fibroblast",
"pos": [
0,
10
]
} | {
"id": "C0007634",
"name": "the",
"pos": [
127,
130
]
} |
immunoglobulins and transient paraproteins in sera of patients with the wiskott-aldrich syndrome : a follow-up study . | NA | {
"id": "C0021027",
"name": "immunoglobulins",
"pos": [
0,
15
]
} | {
"id": "C0030490",
"name": "paraproteins",
"pos": [
30,
42
]
} |
immunoglobulin levels of individual classes and igg subclasses and the occurrence of homogeneous immunoglobulins -- paraproteins -- were studied longitudinally in the sera of three patients with the wiskott-aldrich syndrome ; | NA | {
"id": "C0021027",
"name": "immunoglobulins",
"pos": [
97,
112
]
} | {
"id": "C0030490",
"name": "paraproteins",
"pos": [
116,
128
]
} |
an antigen sharing immunological determinants with doc-extractable tissue antigens was released into circulation before and during proteinuria . | NA | {
"id": "C0003320",
"name": "antigen",
"pos": [
3,
10
]
} | {
"id": "C0003316",
"name": "determinants",
"pos": [
33,
45
]
} |
during intravenous infusion with neutral sodium phosphate , the urine ph changed little but the rate of excretion of titratable acid increased in direct proportion to that of urinary phosphate in both groups of patients . | NA | {
"id": "C0074757",
"name": "sodium phosphate",
"pos": [
41,
57
]
} | {
"id": "C0031603",
"name": "phosphate",
"pos": [
183,
192
]
} |
although intrapartum and postpartum pelvic infections consitute the majority such serious infections in pregnancy , attention has also been called to several less frequent but potentially lethal nonpelvic infections . | NA | {
"id": "C0034041",
"name": "postpartum",
"pos": [
25,
35
]
} | {
"id": "C0032965",
"name": "infections",
"pos": [
205,
215
]
} |
the percentages of patients with normal vitamin a absorption were 85 with vitamin a alcohol in oil-water emulsion , 61 with vitamin a alcohol dissolved in oil , 64 with vitamin a palmitate in oil-water emulsion , and 19 with vitamin a palmitate in oil . | NA | {
"id": "C0042839",
"name": "vitamin a",
"pos": [
40,
49
]
} | {
"id": "C0073115",
"name": "vitamin a palmitate",
"pos": [
225,
244
]
} |
angiotensin in acid-ethanol extracts of kidney were adsorbed on to a cation-exchange resin , eluted and further purified with an immobilized angiotensin ii antiserum , before radioimmunoassay . | NA | {
"id": "C0003018",
"name": "angiotensin",
"pos": [
0,
11
]
} | {
"id": "C0003009",
"name": "angiotensin ii",
"pos": [
141,
155
]
} |
a comparison between the release of fluoride from sodium fluoride lozenges and bone meal tablets . | NA | {
"id": "C0016327",
"name": "fluoride",
"pos": [
36,
44
]
} | {
"id": "C0037508",
"name": "sodium fluoride",
"pos": [
50,
65
]
} |
the release of fluoride from a fluoride-containing bone meal tablet and a chewable sodium fluoride lozenge to 0.5 m perchloric acid , deionized water , and saliva was compared . | NA | {
"id": "C0016327",
"name": "fluoride",
"pos": [
15,
23
]
} | {
"id": "C0037508",
"name": "sodium fluoride",
"pos": [
83,
98
]
} |
the release from the sodium fluoride lozenge ( 0.25 mg f ) was essentially complete in water and saliva as well as in acid . | NA | {
"id": "C0037508",
"name": "sodium fluoride",
"pos": [
21,
36
]
} | {
"id": "C0016327",
"name": "f",
"pos": [
55,
56
]
} |
following sucking and chewing on a sodium fluoride lozenge , the mean salivary fluoride concentration increased from 0.04 to 36 parts/10 ( 6 ) 5 min after intake . | NA | {
"id": "C0037508",
"name": "sodium fluoride",
"pos": [
35,
50
]
} | {
"id": "C0016327",
"name": "fluoride",
"pos": [
79,
87
]
} |
arylesterases from various mammalian sera in relation to cholinesterases , carboxylesterases and their activity towards some pesticides . | NA | {
"id": "C0008429",
"name": "cholinesterases",
"pos": [
57,
72
]
} | {
"id": "C0007067",
"name": "carboxylesterases",
"pos": [
75,
92
]
} |
the findings are discussed in relation to recent studies of continuous recognition memory after head injury and hypotheses concerning neurological dysfunction in head injury . | NA | {
"id": "C0018674",
"name": "head injury",
"pos": [
96,
107
]
} | {
"id": "C0751792",
"name": "neurological",
"pos": [
134,
146
]
} |
sisomicin and gentamicin were tested in vitro against 222 clinical isolates of pathogenic bacteria using the ics agar dilution procedure . | NA | {
"id": "C0037209",
"name": "sisomicin",
"pos": [
0,
9
]
} | {
"id": "C0017436",
"name": "gentamicin",
"pos": [
14,
24
]
} |
ampicillin ( semicillin ) and amoxycillin ( amoxil ) have a strong leptospirocidal effect in vitro and also in vivo . | NA | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
0,
10
]
} | {
"id": "C0002645",
"name": "amoxycillin",
"pos": [
30,
41
]
} |
the patients generally received per os 3 g ampicillin ( semicillin ) or 2 g amoxycillin ( amoxil ) per day over a period of 6 days . | NA | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
43,
53
]
} | {
"id": "C0002645",
"name": "amoxil",
"pos": [
90,
96
]
} |
in the groups treated with ampicillin and amoxycillin the average durations of fever during the treatment were 1.6 and 1.2 days , respectively . | NA | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
27,
37
]
} | {
"id": "C0002645",
"name": "amoxycillin",
"pos": [
42,
53
]
} |
in the first group ( ampicillin ) a 'second wave of fever ' occurred in one case ( 5 % ) and in the second group ( amoxycillin ) , in 0 % ( as compared to 22 % after treatment with benzylpenicillin ) . | NA | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
21,
31
]
} | {
"id": "C0002645",
"name": "amoxycillin",
"pos": [
115,
126
]
} |
in the first group ( ampicillin ) a 'second wave of fever ' occurred in one case ( 5 % ) and in the second group ( amoxycillin ) , in 0 % ( as compared to 22 % after treatment with benzylpenicillin ) . | NA | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
21,
31
]
} | {
"id": "C0030827",
"name": "benzylpenicillin",
"pos": [
181,
197
]
} |
on the basis of our experiences , ampicillin and amoxycillin are strongly recommended for the treatment of human leptospira infections . | NA | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
34,
44
]
} | {
"id": "C0002645",
"name": "amoxycillin",
"pos": [
49,
60
]
} |
a characteristic pattern of dna digestion products is obtained , containing approximately integral multiples of a basic 140 base pair dna segment that resembles very closely the pattern in g2 phase nuclei of physarum and of calf lymphocyte nuclei . | NA | {
"id": "C0000702",
"name": "a",
"pos": [
0,
1
]
} | {
"id": "C0012854",
"name": "dna",
"pos": [
134,
137
]
} |
rna was extracted from isolated salivary glands , enriched for messenger rna by poly u sepharose chromatography , and labelled with 125iodine . | NA | {
"id": "C0035668",
"name": "rna",
"pos": [
0,
3
]
} | {
"id": "C0035696",
"name": "messenger rna",
"pos": [
63,
76
]
} |
in situ hybridization showed that , apart from rrna , balbiani ring 1 and 2 transcripts are the major hybridizing rna species present in this enriched preparation . | NA | {
"id": "C0035701",
"name": "rrna",
"pos": [
47,
51
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
114,
117
]
} |
saturation hybridization levels of rrna and balbiani ring ( br1 plus br2 ) rna with polytene dna from salivary glands were determined and compared with the saturation levels measured for dna from adult flies and larvae . | NA | {
"id": "C0035701",
"name": "rrna",
"pos": [
35,
39
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
75,
78
]
} |
the results suggest that monitering urinary dopamine and 3-methoxytyramine excretion in tourette 's disease may predict the clinical response to pharmacotherapy , and that a dopaminergic mechanism may be associated with this type of motor hyperkinesia . | NA | {
"id": "C0013030",
"name": "dopamine",
"pos": [
44,
52
]
} | {
"id": "C0282151",
"name": "dopaminergic",
"pos": [
174,
186
]
} |
[ effect of different volume rates of artificial blood circulation on hemodynamics in animals resuscitated after death from asphyxiation ] . | NA | {
"id": "C0011065",
"name": "death",
"pos": [
113,
118
]
} | {
"id": "C0004044",
"name": "asphyxiation",
"pos": [
124,
136
]
} |
fecal excretion was the major route of tracer elimination in the rat ( 70 % ) and dog ( 80 % ) , whereas the monkey , baboon , and man excreted the majority of the dose via the urine ( 40-80 % ) . | NA | {
"id": "C1373190",
"name": "fecal",
"pos": [
0,
5
]
} | {
"id": "C1373186",
"name": "route of",
"pos": [
30,
38
]
} |
in a comparison of the antibacterial in-vitro activity of sisomicin , gentamicin , and tobramycine , sisomicin showed a higher activity against e. coli , indole-positive proteus spp . and organisms of the klebsiella-enterobacter-serratia group , whereas tobramycine was superior against pseudomonas spp . | NA | {
"id": "C0017436",
"name": "gentamicin",
"pos": [
70,
80
]
} | {
"id": "C0037209",
"name": "sisomicin",
"pos": [
101,
110
]
} |
however , the differences in activity between sisomicin and gentamicin were only within one step of dilution which is hardly sufficient to guarantee a basic superiority of one or the other preparation for clinical purposes . | NA | {
"id": "C0037209",
"name": "sisomicin",
"pos": [
46,
55
]
} | {
"id": "C0017436",
"name": "gentamicin",
"pos": [
60,
70
]
} |
with corresponding serum levels , almost identical elimination half-lives of 109 and 111 minutes , and recovery values of 84 and 88.4 % , respectively , there were no significant differences in the pharmacokinetics of sisomicin and gentamicin . | NA | {
"id": "C0037209",
"name": "sisomicin",
"pos": [
218,
227
]
} | {
"id": "C0017436",
"name": "gentamicin",
"pos": [
232,
242
]
} |
thus in the antibacterial treatment of gentamicin-sensitive gram-negative organisms sisomicin presents an equally good alternative . | NA | {
"id": "C0017436",
"name": "gentamicin",
"pos": [
39,
49
]
} | {
"id": "C0037209",
"name": "sisomicin",
"pos": [
84,
93
]
} |
with organisms only moderately sensitive or resistant to gentamicin , sisomicin , tobramycine and amikacin should be additionally tested . | NA | {
"id": "C0017436",
"name": "gentamicin",
"pos": [
57,
67
]
} | {
"id": "C0037209",
"name": "sisomicin",
"pos": [
70,
79
]
} |
the effect of beta-sitosterol on the lipid and lipoprotein level was evaluated in a randomised double-blind cross-over trial in 24 patients with primary familial type ii hyperlipoproteinaemia over a period of 16 weeks . | NA | {
"id": "C0023779",
"name": "lipid",
"pos": [
37,
42
]
} | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
175,
186
]
} |
a cure was achieved after long-term administration of penicillin g in high doses , at first combined with ampicillin . | NA | {
"id": "C0030827",
"name": "penicillin g",
"pos": [
54,
66
]
} | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
106,
116
]
} |
when individual hcg subunits were treated with the same reagent , the number of tyrosyls acetylated in each subunit again increased with increasing amounts of reagent , up to three in the alpha subunit and two in the beta subunit in the absence of urea . | NA | {
"id": "C0018062",
"name": "hcg",
"pos": [
16,
19
]
} | {
"id": "C0017963",
"name": "alpha subunit",
"pos": [
188,
201
]
} |
injection of frogs with beta-adrenergic catecholamines produced a selective desensitization ( loss of responsiveness ) of the erythrocyte membrane adenylate cylase to subsequent stimulation in vitro by isoproterenol . | NA | {
"id": "C0007412",
"name": "catecholamines",
"pos": [
40,
54
]
} | {
"id": "C0022245",
"name": "isoproterenol",
"pos": [
202,
215
]
} |
effects of excess iodide and other anions on thyroid hormone secretion in normal or hypophysectomized rats treated with graded doses of thyroid hormone . | NA | {
"id": "C0021966",
"name": "iodide",
"pos": [
18,
24
]
} | {
"id": "C0003075",
"name": "anions",
"pos": [
35,
41
]
} |
the stimulatory action on thyroid hormone secretion was specific for iodide and was not shared by other anions . | NA | {
"id": "C0021966",
"name": "iodide",
"pos": [
69,
75
]
} | {
"id": "C0003075",
"name": "anions",
"pos": [
104,
110
]
} |
abp activity was also increased by intratesticular injection of an analog of cyclic amp , 8-bromo camp . | NA | {
"id": "C0001455",
"name": "cyclic amp",
"pos": [
77,
87
]
} | {
"id": "C0000661",
"name": "8-bromo camp",
"pos": [
90,
102
]
} |
glu and gln were predominant amino acids in the caput , and their amounts occupied more than half of the total ninhydrin reactive compounds . | NA | {
"id": "C0061472",
"name": "glu",
"pos": [
0,
3
]
} | {
"id": "C0017797",
"name": "gln",
"pos": [
8,
11
]
} |
such a high concentration of glu and gln was not observed either in the cauda or in the testis . | NA | {
"id": "C0061472",
"name": "glu",
"pos": [
29,
32
]
} | {
"id": "C0017797",
"name": "gln",
"pos": [
37,
40
]
} |
testosterone treatment to castrated animals did not restore glu and gln contents in the pressed fluid from the caput epididymis to the level observed in intact rats completely . | NA | {
"id": "C0061472",
"name": "glu",
"pos": [
60,
63
]
} | {
"id": "C0017797",
"name": "gln",
"pos": [
68,
71
]
} |
fluctuations of ovarian biosynthetic activity and effects of exogenous lh and fsh on it during the estrous cycle were investigated by measuring in vitro transfer rates of 14c from 14c-1-acetate into progesterone ( p ) , 20 alpha-hydroxy-pregn-4-en-3-one ( 20 alpha-oh-p ) and estrogen ( estradiol and estrone , e ) in the ovarian homogenates from rats autopsied at 2 hour intervals . | NA | {
"id": "C0033308",
"name": "progesterone",
"pos": [
199,
211
]
} | {
"id": "C0012311",
"name": "20",
"pos": [
256,
258
]
} |
the time course of the release of labelled dna into the fraction of dna soluble in 0.14 m nac1 indicates that a fraction of labelled dna was rapidly removed from the spleen after injection of cortisol . | NA | {
"id": "C0012854",
"name": "dna",
"pos": [
43,
46
]
} | {
"id": "C0000702",
"name": "a",
"pos": [
173,
174
]
} |
the similarity to the kidney enzyme was confirmed by the use of polymerization in phosphate borate of the isozyme from a mammary carcinoma to effect its purification . | NA | {
"id": "C0014442",
"name": "enzyme",
"pos": [
29,
35
]
} | {
"id": "C0022173",
"name": "isozyme",
"pos": [
106,
113
]
} |
the pheromones usually depend on the sexual hormones ( pheromones of sexual attraction which promote or inhibit aggression , etc . ) | NA | {
"id": "C0031516",
"name": "pheromones",
"pos": [
4,
14
]
} | {
"id": "C0036863",
"name": "pheromones",
"pos": [
55,
65
]
} |
in the past widespread use was made of cheap synthetic estrogens such as diethylstilbestrol and hexestrol . | NA | {
"id": "C0012203",
"name": "diethylstilbestrol",
"pos": [
73,
91
]
} | {
"id": "C0019467",
"name": "hexestrol",
"pos": [
96,
105
]
} |
chromatographic behaviour of various metal cations in fused salts on gamma-alumina and synthetic inorganic ion exhange materials . | NA | {
"id": "C0007447",
"name": "cations",
"pos": [
43,
50
]
} | {
"id": "C0022023",
"name": "ion",
"pos": [
107,
110
]
} |
[ comparative studies on the histotopochemical properties of tetrazolium salts mmt , nitro-bt and tnbt in enzyme histochemistry ] . | NA | {
"id": "C0039704",
"name": "tetrazolium salts",
"pos": [
61,
78
]
} | {
"id": "C0028147",
"name": "nitro-bt",
"pos": [
85,
93
]
} |
separation of lipids from whole leaves and from their chlorophyll lipoprotein of sapium sebiferum roxb . | NA | {
"id": "C0023779",
"name": "lipids",
"pos": [
14,
20
]
} | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
66,
77
]
} |
it is devoid of lipid and separate from the streptolysin o inhibitory lipoprotein that is also induced by administration of the streptococcal toxin . | NA | {
"id": "C0023779",
"name": "lipid",
"pos": [
16,
21
]
} | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
70,
81
]
} |
the factor , moreover , appears clearly distinct from haptoglobin or c-reactive protein and seems to be a unique type of acute phase protein . | NA | {
"id": "C0018595",
"name": "haptoglobin",
"pos": [
54,
65
]
} | {
"id": "C0001347",
"name": "acute phase protein",
"pos": [
121,
140
]
} |
the factor , moreover , appears clearly distinct from haptoglobin or c-reactive protein and seems to be a unique type of acute phase protein . | NA | {
"id": "C0006560",
"name": "c-reactive protein",
"pos": [
69,
87
]
} | {
"id": "C0001347",
"name": "acute phase protein",
"pos": [
121,
140
]
} |
[ biosynthesis in vitro of vitamin b12 and other cobalamins by bacterial strains isolated from the digestive tract of the rat ] . | NA | {
"id": "C0042845",
"name": "vitamin b12",
"pos": [
27,
38
]
} | {
"id": "C0086024",
"name": "cobalamins",
"pos": [
49,
59
]
} |
effects of added electrolytes on the aggregation rates of latex particles in aqueous ionic surfactant solutions . | NA | {
"id": "C0013832",
"name": "electrolytes",
"pos": [
17,
29
]
} | {
"id": "C0022023",
"name": "ionic",
"pos": [
85,
90
]
} |
[ sensitivity of 207 staphylococcus aureus strains to penicillin g , penicillin v , methicillin , cloxacillin and oxacillin ] . | NA | {
"id": "C0009077",
"name": "cloxacillin",
"pos": [
98,
109
]
} | {
"id": "C0029983",
"name": "oxacillin",
"pos": [
114,
123
]
} |
[ glycoproteins and mucoproteins in bone marrow blood and peripheral venous blood in diverse disease conditions ] . | NA | {
"id": "C0017968",
"name": "glycoproteins",
"pos": [
2,
15
]
} | {
"id": "C0026714",
"name": "mucoproteins",
"pos": [
20,
32
]
} |
[ determination by thin layer chromatography of some phospho-organic insecticides : parathion , methylparathion , diazinon , malation , gusation , metasystoks and dipterex ] . | NA | {
"id": "C0030514",
"name": "parathion",
"pos": [
84,
93
]
} | {
"id": "C0025709",
"name": "methylparathion",
"pos": [
96,
111
]
} |
[ study of displacement reactions between polyribonucleotides by use of ethidium hydrobromate ( etb ) . demonstration of displacement of the poly ( a-2 i ) by poly u ] . | NA | {
"id": "C0032590",
"name": "polyribonucleotides",
"pos": [
42,
61
]
} | {
"id": "C0032413",
"name": "poly",
"pos": [
159,
163
]
} |
[ study of displacement reactions between polyribonucleotides by use of ethidium hydrobromate ( etb ) . demonstration of displacement of the poly ( a-2 i ) by poly u ] . | NA | {
"id": "C0032590",
"name": "polyribonucleotides",
"pos": [
42,
61
]
} | {
"id": "C0032417",
"name": "poly",
"pos": [
159,
163
]
} |
interrelation between human chorionic gonadotrophin inhibitory activity in plasma and urine and the rate of urinary gonadotrophin excretion . | NA | {
"id": "C0018062",
"name": "human chorionic gonadotrophin",
"pos": [
22,
51
]
} | {
"id": "C0018061",
"name": "gonadotrophin",
"pos": [
116,
129
]
} |
the radioactive material in urine after parenteral radioactive hydroxocobalamin is composed of radioactive cyanocobalamin , radioactive hydroxocobalamin , and a radioactive anionic complex . | NA | {
"id": "C0042845",
"name": "cyanocobalamin",
"pos": [
107,
121
]
} | {
"id": "C0020316",
"name": "hydroxocobalamin",
"pos": [
136,
152
]
} |
comparison of the amounts of radioactive and microbiologically active material in urine after parenteral radioactive hydroxocobalamin show a significant correlation both in the first and second 24 hours after injection showing that the amount of radioactivity is an acceptable measure of the loss of cobalamin in urine . | NA | {
"id": "C0020316",
"name": "hydroxocobalamin",
"pos": [
117,
133
]
} | {
"id": "C0042845",
"name": "cobalamin",
"pos": [
300,
309
]
} |
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