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3,900
Concentration and saturation of hemoglobin measurements in all three subjects were within previously reported values in animal [35,51] and human [37,43,56] brain.
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background
3,901
We applied a maximum likelihood approach using the ‘distribution of fitness effects’ program (DoFE; [27, 28]).
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method
3,902
…paralysis and show a very prominent lower motor neuron disease (Gurney et al., 1994; Bendotti et al., 2001; Martin et al., 2007), the details of the cellular and molecular pathology appear to be distinct from that seen in human ALS (Martin, 1999, 2010a; Martin and Liu, 2004; Martin et al., 2007).
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background
3,903
Effects of CACC inhibitors were analyzed by the following four-parameter logistic function: y min (max min)/[1 (x/IC50) Hill slope], where min and max are the bottom and top of the curve, respectively, IC50 is the concentration of half inhibition of block, and the Hill slope is a reflection of the steepness of the curve.
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method
3,904
Few studies demonstrated the importance of alexithymia among suicidal patients, but the results were not consistent (Sayar & Acar 2003, Hintikka et al. 2004, Iancu et al. 1999).
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result
3,905
1997), fertilization in flowering plants (Digonnet et al. 1997), pollen germination, pollen tube growth (Li et al.
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method
3,906
This likely is attributable to the extensive amount of soft tissue and bone that must be removed during tumor resection [17, 23, 32].
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background
3,907
Dermoscopy is cost-effective and its use increases the diagnostic accuracy by 5-30% over visual inspection [26].
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background
3,908
We propose to use a family of densities parametrized by functions belonging to a Reproducing Kernel Hilbert Space (RKHS) HY with positive semidefinite kernel k (Canu et al., 2006; Fukumizu, 2009; Sriperumbudur et al., 2017).
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method
3,909
As for SDH-related PPGL, FH-related paragangliomas present a pattern of global histone and DNA hypermethylation evocating that fumarate acts, like succinate, as an oncometabolite (Castro-Vega et al., 2014; Letouze et al., 2013; Morin et al., 2014).
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background
3,910
The main specifications we shall deal with here are (Landau et al., 1995b): • stability of the loop [C G0] • a maximum value of less than 6 dB for the sensitivity function T22(G0, C) = 1/(1 + G0C).
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background
3,911
Nevertheless, this less time-demanding and less expensive questionnaire, that requires less collaboration from participants than the usual full length food frequency questionnaires or other more comprehensive methods, has previously been validated by different clinical observational and interventional studies and accurately classified participants with respect to scoring for different validated methods [26].
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result
3,912
The relationship between DNA content and absorbance at 600 nm is linear [17], allowing the amount of DNA in each unknown sample to be determined from the standard curve.
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background
3,913
A tentative explanation for the negative findings on the relationship between the cumulative dose of MA and ACC dysfunction is that the developmental stage exposed to MA rather than its dosage may play a more prominent role in determining the effects of MA on the developing brain (Lyoo et al. 2015).
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background
3,914
Clinical variables, such as the type of presenting complaint [13], health and mental health status [4, 14, 15], and diagnosis and severity of illness [16, 17, 18] have also been shown to affect the use of psychiatric services.
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background
3,915
The signal-transduction pathway targeting c-Myb Cys43 is likely to involve either an oxidative modification, such as an aldehyde adduct (6, 10, 24, 42), or a nitrosylation of Cys43 (12, 48), because the Cys43 mutation would be refractory to either pathway.
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background
3,916
…differentially expressed during in vitro xylem differentiation in Arabidopsis suspension cells showed that AtGATL6 and AtGATL9 expression levels decreased rapidly before xylem vessel element formation (Kubo et al., 2005), further supporting a role for these two genes in primary cell wall synthesis.
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background
3,917
Compared to other primate habitats, Madagascar is unusually susceptible to droughts, cyclones, periods of frost and cold, and a highly seasonal fruit supply (Wright 1999).
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background
3,918
subjective OSATS GRS has high interobserver reliability and proven utility in assessing vessel ligation.(13,14) Scores on the GRS items were averaged to produce a representative composite score.
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method
3,919
…studies that the GABAB(1a) isoform was predominantly expressed in the granule cell layer, while the GABAB(1b) isoform was expressed mainly in the Perkinje cells (Billinton et al. 1999; Bischoff et al. 1999; Fritschy et al. 1999; Kaupmann et al. 1998b; Liang et al. 2000; Poorkhalkali et al. 2000).
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background
3,920
Unlike many previous studies (Landry et al. 2005, McManus et al. 2010, Malone and Michalak 2008, Renaut et al. 2009, Bell et al. 2013, Coolon et al. 2014), we found that misexpression was rare among the genes we measured in hybrid zebra finches.
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result
3,921
…was observed at 18–24 ◦C, and similar results have been observed in G. tikvahiae McLachlan (Bird et al., 1979), G. chilensis (Laing et al., 1989 as G. sordida Nelson); Yokoya and Oliveira, 1992, Gracilaria sp. (chorda-type) (Chirapart et al., 1994), and G. vermiculophylla (Yokoya et al., 1999).
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result
3,922
aeruginosa secretes the endogenous proteases elastase and alkaline protease, which degrade and inactivate human complement components, including C1q, C2, and C3b (12, 13).
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background
3,923
Few studies (Zakhartchenko et al., 2001; Arat et al., 2001; Bhuiyan et al., 2004) have evaluated the effects of long-term culture and genetic manipulation of adult somatic donor cells for NT in bovines.
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background
3,924
We selected the Kyte-Doolittle hydropathy profile [37] for hydrophobicity, the Grantham’s profile [22] for polarity and Klein’s scale for net charge [35].
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method
3,925
and 5% HCF (Origen hybridoma cloning factor, TEBU, Frankfurt/M, Germany) in order to test the culture supernatants for antibody response in ELISA.(29) The culture supernatant from the C3H/J splenocytes used for RNA extraction indicated the presence of TF-binding antibodies, whereas the supernatants from the other mice were negative (data not shown).
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background
3,926
…the previous reports on the toxicokinetics of p-DCB in animals, in which the major route of excretion is the urine (Hawkins et al. 1980; Klos and Dekant 1994; Hissink et al. 1996, 1997), the major route for the elimination of p-DCB in humans was assumed to be metabolism and then excretion in urine.
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background
3,927
Data analysis: Primers for SSU rDNA genes are from Medlin et al. (1988) with three additional primers used to generate overlapping sequences from each clone as described in Snoeyenbos-West et al. (2002).
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method
3,928
In such a model, a process can simultaneously request multiple resources and remains blocked until it is granted any one of the requested resources [16].
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background
3,929
For source coding and rate-distortion coding problems, polar codes have been shown to be competitive with the state-of-the-art methods [2], [3].
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background
3,930
, 2007) and ultrastructural approaches (Fukaya et al., 2008), as well as to define the precise location of nuclear PLCb1 in native nervous tissue.
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background
3,931
In this experiment, we have seen evidence that, contrary to the results of Erkelens (2008), Frequent Frames may yield high accuracy and completeness in categorizing Dutch
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result
3,932
…themselves, as has been proposed previously [e.g., Bindschadler et al., 1992a, 1992b; Bindschadler, 1995; Hansen et al., 1997, 1999, 2000; Gilmore et al., 1998; Ghent and Hansen, 1999], then the structures preserved in crustal plateaus can provide important insights into Venus’ geological history.
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background
3,933
3 Experimental Results All three methods proposed in the chapter were tested on the MERL sequences, Ballroom, Vassar and Exit [111].
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method
3,934
Given that the CA1 subfield predominates in the anterior hippocampus but extends throughout its antero-posterior axis, the specific role of CA1 structural damage in episodic encoding deficits evidenced here in aMCI is therefore consistent with both hypotheses of an anterior (Lepage et al., 1998) and an antero-posterior (Schacter and Wagner, 1999) in se rm -0 06 42 17 6, v er si on 1 21 N ov 2 01 1
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result
3,935
The over-expression of EGFR (erbB-1 receptor) is seen in 20% to 81% of breast tumours, whereas HER2 receptor overexpression is seen in approximately 20% [1-4].
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background
3,936
Some other studies have offered interpretations different from our result, namely that Ambulocetus and desmostylians were capable of terrestrial locomotion on all four limbs or on bellies like extant seals (i.e. Thewissen et al. 1994; Madar et al. 2002; Inuzuka, 2005, 2009).
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result
3,937
Achenbach (1991) has shown that the YSR and its subscales are reliable and valid measures of problematic behaviors among clinic-referred and nonreferred youths, and further research documents that the measure is reliable and valid for youths as young as 7 years old (Ebesutani et al. 2011; Yeh and Weisz 2001).
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method
3,938
The surface sections of all implants irradiated in vacuum showed a chemical compound similar to that of a non-irradiated reference [15].
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background
3,939
2e, Fdps-Luc, Msmo1-Luc, and Dhcr24-Luc (10 ng) were transfected into Y-1 cells along with expression plasmids of Ad4BP/SF-1 (300 ng) and transcriptionally active SREBP-2 (1-481) (100 ng)44.
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background
3,940
The barn owl shows a third type of pattern; there is only a small increase of the hair cell number in a cross section in the basal half of the papilla, followed by a more rapid but continuous increase in the apical half (Fischer et al., 1988; Smith et al., 1985).
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background
3,941
A cut-point maximizing the concordance probability will thus maximize the rectangle [6].
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background
3,942
TAPSE < 16 indicates RV systolic dysfunction according to ASE guidelines.(11) In our study, TAPSE 16 predicted proximal RCA lesion with a sensitivity of 92.
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method
3,943
In [1] and [2], a multilayer directory structure is presented to reduce the size of the directory for largescale configurations of a multiprocessor while also maintain or even improve the performance.
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background
3,944
Subjects received an intravenous injection of 1110 MBq 99mTc-ECD (ethylcysteinate dimer, Neurolite, Bristol-Myers Squibb Pharma), and were imaged by a dual-head rotating gamma camera (VG MILLENIUM GE), according with European procedure guidelines [9].
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method
3,945
According to this view, and for individuals for whom reading has become automated, the strength of the reading response (or strength of its activation) is higher than that of the naming response (MacLeod, 1991).
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background
3,946
Our findings confirm previous reports [11-14,27], but several issues need to be considered when interpreting our results.
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result
3,947
A record-low EDDR of 99 fJ/(bit·km) is achieved with our devices at 17 Gb/s across 1 km of MMF [7].
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background
3,948
Our data are in line with published results, that assign NOXA and PUMA overlapping and distinct regulations by p53 depending on the experimental setting.(3,5,20,21)
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result
3,949
The analysis relied heavily on the open-source BioPerl (Stajich et al., 2002) modules available at www.
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method
3,950
In the case of a real option to invest, Nishimura and Ozaki (2007) show that ambiguity impacts the value of irreversible investments in a « drastically » different manner from that of “traditional uncertainty” (risk).
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background
3,951
, 2009; Dedrick et al., 2010) have received a great deal of attention. Xing and Detert (2010) examined the case of the iPhone and found that China just contributed only 3.
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background
3,952
The alcohol myopia theory (Steele and Josephs 1990) states that alcohol intoxication restricts attentional capacity resulting in people in sexual contexts after drinking not being able to process their distant risk cues (such as HIV or sexually transmitted infection (STI) risks) and be highly influenced by the most immediate cues (such as sexual arousal) in their environment (MacDonald et al. 2000).
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background
3,953
Genetic variation Based on ISSR analysis, the high genetic variation observed in P. squarrosa in a previous study (Spagnuolo et al. 2007) was substantially confirmed in this study.
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background
3,954
Our results further confirm previous findings on the differential regulatory mechanisms for Hoxa3 and Hoxb3 expression in r5 and r6 by kreisler (Manzanares et al., 1997, 1999a,b, 2001).
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result
3,955
There is overwhelming evidence that the Indus, Brahmaputra, and Ganges Rivers, existed as separate river systems soon after the original India-Asia collision (~55–45 Million Years (MY) ago) and even before large-scale elevation of the Himalayan mountains (Clift and Blusztajn 2005).
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background
3,956
or (b) the existence of spontaneous reactivation (Estévez and Vilanova 2009).
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background
3,957
Furthermore, it is also known that Ras protein promotes ARC production and hinders its degradation (Hassen et al. 2012; Li et al. 2008; Ludwig-Galezowska et al. 2011; Green and Kroemer 2009; Foo et al. 2007)
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background
3,958
Prdm1 is a positive control, as it encodes an inhibitor of Tfh cell differentiation (Johnston et al., 2009), and is discussed further below.
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background
3,959
Interestingly, several previous studies have investigated the possible association between coping strategies, suicidal behaviour, suicidal ideation and suicide risk (D’Zurilla et al., 1998; Li & Zhang, 2012; Pietrzak et al., 2011; Sugawara et al., 2012; Tang & Qin, 2015).
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background
3,960
As a consequence if activation of NF-kB can be inhibited then it can be used as a possible strategy for prevention of secondary damage in SCI [14, 15].
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method
3,961
The results of this study confirm and extend the findings of other studies (Dorn et al. 1999; Gorga et al. 2005) regarding the superiority of multivariate analyses of DPOAE data.
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result
3,962
Patients with rheumatoid arthritis have an increased risk of developing gastro-intestinal tract lesions [35-37] and for this reason, the prevalence of H.
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background
3,963
We implemented the extended HCAP protocol in Java.2 The implementation is based on CoAP [36], a lightweight, UDP-based variant of HTTP commonly used in IoT environments.
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method
3,964
Furthermore, late gadolinium enhancement (LGE) CMR [21,22] can depict the left atrial wall injury after the radiofrequenty ablation for treatment of AF [23,24].
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background
3,965
[17], using the same database as the present study, recently reported on the effect of a number of risk factors on the survival of patients in the VS.
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method
3,966
Six classifiers, E1, E2, E3, E4, E5, E6, are used for the recognition experiments of the unconstrained handwritten numerals from Concordia University [10] and the University of California, Irvine (UCI) [1].
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method
3,967
Another population of Astyanax eigenmanniorum, from Caetano stream, Uberlandia/MG, analyzed by Torres-Mariano and Morelli (2008), showed a formula of 14m + 18sm + 10st + 6a, constituted by a greater number of meta- and submetacentric chromosomes (32), compared with the results obtained in this…
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result
3,968
However, users may also browse the validation metrics to choose their own preferred assembly, such as one that optimizes consensus accuracy without regard to continuity. iMetAMOS is primarily written in Python and builds upon Ruffus [31] for pipeline management.
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method
3,969
Hybridization was performed overnight at 42°C, as described (18), and the membranes were washed at low stringency (23 SSC, 0.
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method
3,970
A VARIETY OF MEAL-RELATED stimuli, such as gastricdistending loads (19), duodenal nutrient infusions (11, 30, 31), and meal-induced gut-brain peptides, such as CCK (11), have all been shown to suppress ingestive behavior and food consumption.
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background
3,971
2. deeper understanding of brain functions involved in these interactions (Chaminade et al., 2007); 3. better engineering guidelines in building machines (as suggested by Cheng et al., 2007) suitable for human interactions.
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background
3,972
The impact of WNV on public health in Guatemala and throughout tropical America remains unresolved.(1,36) Our study
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background
3,973
The ranking of the tissues in terms of their protein synthesis rates was similar to that previously reported from crustacean studies (21) and is in agreement, so far as the tissues are comparable, with the results from fish (11, 37).
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result
3,974
Although originally described as a potent stimulator of glucose-dependent insulin secretion, recent studies [1, 2, 3, 4, 5, 6, 7, 8, 10, 11, 12, 13] have shown that the intestinal hormone GLP-1 also prevents the onset of diabetes and ameliorates existing diabetes through a mechanism that includes enhancement of beta-cell mass [16, 17, 18, 19, 20].
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3,975
However, when testing the effect of S-nitroso- L-cysteine a different approach was used since this compound has a half-life of less than 30 s (Myers, Minor, Guerra, Bates & Harrison, 1990; Bates, Aldape & Baker, 1991).
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method
3,976
It was apparent that the AlkOH group content was comparable with previous results obtained with the one-stage organosolv pretreatments of poplar performed at milder conditions (165 C, 40 min, 1.0% H2SO4), (Pan et al., 2006b).
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3,977
[21] confirmed these findings while another study has shown that dry bonding does not necessarily lead to an insufficient hybrid layer formation [22].
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3,978
In conclusion, the present results support an earlier observation (Rowan et al., 1994) that there is a good agreement between pigs and humans for their true ileal digestibility of dietary protein.
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result
3,979
coli strain (Stratagene/ Agilent Technologies, Santa Clara, CA), extracted from the inclusion bodies, and purified to about 95% electrophoretic homogeneity as previously described in detail [30].
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method
3,980
CRS-induced behavioral anomalies are accompanied by oxidative stress and neuroinflammation in different brain regions such as hippocampus (HC) and prefrontal cortex (PFC) (McEwen and Magarinos 1997; Chiba et al. 2012).
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background
3,981
The bimodality of gene expression was scored for each gene within each dataset using MCLUST [48] and the Bimodality Index (BI) [49].
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method
3,982
Male túngara frogs (Physalaemus pustulosus) give evoked vocal responses to a larger range of heterospecific and ancestral mating calls than females will approach during playback trials (Bernal et al. 2007).
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3,983
The buckled structure of silicene is due to the preference of Si atoms to adopt both sp3 and sp2 hybridization rather than adopting sp2 hybridization alone, as in graphene [1].
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background
3,984
Each set of samples was hybridized to microarrays containing oligonucleotide probes complementary to 173 known miRNAs (29).
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3,985
These results are in line with several other studies (Mattson 1980; Ayres and MacLean 1987; Kause et al. 1999; van der Wal et al. 2000; Graglia et al. 2001; Lempa et al. 2004; Hansen et al. 2006).
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3,986
It was shown, for example, that the transcription and translation of genes that participate in antioxidant machinery (8), DNA repair, and cell cycle regulation are required for the adaptive response in human lymphocytes and fibroblasts (9, 10).
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3,987
Table 4: Number of function evaluations reported for the particle swarm optimization (PSO) [7] and contact interactions (CI) [8] methods and calculated for our AGAHP implementation for protein chains 27 amino acids in length.
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3,988
A recent study indicated that COX-2 was related to UA-activated proliferation of smooth muscle cells possibly via TXA2 [7].
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3,989
multiple equilibria, see Albanesi et al. (2003), King and Wolman (2004) and Blake and Kirsanova (2012), and a simple New Keynesian model is not appropriate to investigate many consequences of policy delegation. As there is no particular reason to assume one equilibrium will prevail any more than another, even if the delegation schemes behave locally as intuition might suggest globally could be a different matter. The central questions addressed in this paper follow on from this. How do delegation schemes affect the likelihood of obtaining multiple equilibria in more realistic models? If multiplicity survives, how should we quantify the welfare implications of choosing one of these delegation schemes? Can any of these schemes affect the likelihood that economic agents successfully coordinate on the best equilibrium? To address these questions we study a version of the familiar sticky price model modified to incorporate capital accumulation (Sveen and Weinke, 2005; Woodford, 2005). This model contains all the features as at the heart of many DSGE models used in policy analysis which makes it a ‘representative agent’ for our policy analysis. Moreover, we choose a set up which encompasses the ‘worst case’ scenario: there are expectation traps and economic agents may be more likely to coordinate on the worst equilibrium (Dennis and Kirsanova, 2012). We confirm the previous results that all these delegation schemes can improve social welfare, but we show that they only unequivocally improve welfare if the economy remains in the best equilibrium. At the same time, we demonstrate that none of the considered delegation schemes eliminates expectation traps, moreover, new equilibria arise under delegation. Whether there is a gain associated with a transition to a delegation scheme will depend on which equilibrium under the original unmodified objective one starts from and to which equilibrium one transitions. More encouragingly, all delegation schemes reduce the range of parameters which ensure the unique worst...
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3,990
P ra sa th ) mutant embryos (Deng et al., 1994; Yamaguchi et al., 1994; Sun et al., 1999; Guo and Li, 2007).
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3,991
The subcellular localization of each enzyme was accomplished by differential sedimentation and isodensity centrifugation as described by Lindmark (1988).
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method
3,992
The prevalence of trzN over atzA gene in the soil environment reported by Arbeli and Fuentes (2010) might explain why it was often encountered in our experiment.
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3,993
In order to avoid issues with data sufficiency, we aggregated these 25 types into nine classes based on provided descriptions from the California Department of Fish and Game (1988).
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3,994
…indicates that cholinergic and glutamatergic functions regulate cortical development and may contribute to postnatal critical periods (Bear and Singer, 1986; Hohmann et al., 1991; Robertson et al., 1998; for review, see Hohmann and Berger-Sweeney, 1998; Fox et al., 1999; Yuste and Sur, 1999).
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3,995
…software package from DNASTAR, alignments were created by the Lipman–Pearson Method (Lipman and Pearson, 1985). cDNA library screening by NSH (Ray et al., 2004) To create a cDNA library that is enriched for transcript copies specific for fruiting body formation of A. nidulans, total RNAs…
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3,996
5 D or more in some situations.(21,22) The tolerance for position error for toric andmultifocal IOLs is even less, so small amounts of tilt, decentration, or rotation of these IOLs can result in significant deviations from the desired refractive outcome as well as symptomatic visual aberrations.
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3,997
…both 3 and 5 directions were assembled using the programs phred (Ewing and Green 1998; Ewing et al. 1998), phrap (http://www.phrap.org) and Consed (Gordon et al. 1998), and were submitted to the GenBank (http://www.ncbi.nlm.nih.gov/blast) and Rhizobase databases…
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3,998
In contrast, the plasma AChE activity levels detected in Gallotia galloti were lower than the activity of BChE (Sanchez-Hernandez and Moreno 2002).
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3,999
We conducted several experiments to compare the proposed detection methods with one of the scene text detection methods (STD) [8], SBD [5] and TLD [6].
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method