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2,800
Replacing behaviors associated with a low energy expenditure by just 10 min of MVPA per day can have a significant impact on health outcomes such as obesity [16, 24].
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method
2,801
We assume the remote system has a complex classifier f0, in our experiments 500 gradient boosted trees using XGBoost [4].
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method
2,802
Though we would eventually like to include a discovery module in our implementation that assembles the required knowledge bases dynamically by identifying suitable content on the semantic Web, for example, through the automatic generation of queries issued to semantic repositories such as Bio2RDF [15, 16] and DBpedia [17], the current implementation requires manual intervention during the composition of the needed datasets.
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method
2,803
However, from that data we can not draw any conclusions regarding the relationship between public and See Takalo (2012) for a survey on public innovation policies.
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background
2,804
1.5 Variant annotation We used the ANNOVAR [10] tool (version 2013-02-21) to annotate SNPs and indels.
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method
2,805
However, from that data we can not draw any conclusions regarding the relationship between public and 1See Takalo (2012) for a survey on public innovation policies.
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background
2,806
Sijen et al. (2001) described silencing of the endogenous dfrA promoter in Petunia.
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background
2,807
[24] showed that the above optimization can be performed efficiently by sorting the samples xk in descending order of the score w ψ(xk).
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method
2,808
Previously, a phosphoproteomic study demonstrated that AbfR1 is phosphorylated in vivo at a tyrosine and serine residue, Y84 and S87 (Reimann et al., 2013).
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background
2,809
, 1991) and have a lower OX1 expression than haematogenously derived cells (Sedgwick et al., 1991).
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background
2,810
Based on the Born method, aggregation measurements provide an aggregation index curve describing the light transmission intensity changes of the PRP samples (15, 64).
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method
2,811
(E) Sensorgram for FLNA(16-23) binding kinetics to immobilized ICL3 peptide as in D.
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method
2,812
We administered the Conflict Resolution Style Inventory (CRSI; Kurdek, 1994) [40] to measure adolescents’ style of handling conflicts in the current romantic relationship.
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method
2,813
…Spire1C KIND domain decreases ER-mitochondria overlaps Since ER tubules have been implicated in mitochondrial constriction and division (Friedman et al., 2011; Korobova et al., 2013; Murley et al., 2013; Korobova et al., 2014), we investigated whether Spire1C influences ER-mitochondria association.
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background
2,814
Similar N-acylation of the acetamide and/or N, N-diacyl substitutions were previously reported for the acylation of chitosan [16] and chitin [5, 9].
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background
2,815
Expression values were extracted using two model-based expression indexes as implemented in the dChip package (Li and Wong, 2001a) using default parameters and normalization.
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method
2,816
To assess whether distractor size manipulations also affected hand transport control, the maximum tangential velocity of the wrist marker in the plane of the work surface, a conventional and sensitive index of hand transport was also calculated (Gentilucci et al. 1991; Jakobson and Goodale 1991).
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background
2,817
In this chapter, we focus on the use of two-photon laser scanning microscopy, which has enabled the monitoring of hundreds of individual neurons in anesthetized (26), awake and behaving animals (9, 11, 27, 28) as well as neurotransmitter uncaging at the level of individual dendritic spines (29, 30) or at many discrete sites simultaneously (15).
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2,818
[23] emphasized the memorability of phrases, and proposed a method for sampling memorable and representative phrase sets based on a multiple regression model.
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method
2,819
These results suggest that H2O2 was not involved in the osmotic stress-ethylene production, which is inconsistent to the results described by Watanabe and Sakai (1998) in winter squash (Cucurbita maxima), who suggested H2O2 would be involve to the expression of gene for a would-inducible 1-…
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result
2,820
The inhibition of down-regulation of HMGA2 by gene knockdown of unrelated ALKs based on the current signaling model [4–7] may be indirect effect, because gene expression was examined at 24 h after ligand stimulation.
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background
2,821
Contrary to our finding, the association of long intervals and pregnancy complications, such as pre-eclampsia, preterm birth and SGA,were also reported in some studies.4,7 Conflicting results may be due to lack of standardized definitions used for IPI.
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result
2,822
[12] At neuroimaging, venous hypertension and cerebral edema caused by straight sinus thrombosis typically result in high signal intensity in the bilateral thalami and basal ganglia.[1,6] In the present case, FLAIR showed characteristic hyperintensity in the bilateral basal ganglia and thalami as mentioned above.
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2,823
The reviewed articles also addressed e-health readiness assessment from varying perspectives, such as electronic medical records,(18) telemedicine,(14) rural communities,(13,14,21) or developing countries.(3,10,11,19) Discussion
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background
2,824
Breese et al. (1998) present a number of different algorithms for collaborative filtering, including two Bayesian approaches.
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method
2,825
1; and Slobounov et al. 1997, 1998; Haibach et al. 2007; Slobounov et al. 2008 for details).
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background
2,826
However, this resistance to drought is much lower than observed for many Pulmonates which may survive several months or even more to the desiccation (Barbosa and Barbosa 1959; Cridland 1967; Véra et al. 1994).
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2,827
Consistent with previous studies [19] and guidelines and recommendation for weight loss [26-28], our results showed that most of the GPs gave advice on lifestyle, dietary and physical activity.
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result
2,828
Our finding is consistent with other studies which have also highlighted the involvement of this novel molecule, Ara-LAM, in inducing proinflammatory responses (IL-8, TNF-a) in macrophages via interacting with TLR-2 [26,27].
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result
2,829
A comparison of the chemical structures of equol and estradiol (Setchell et al. 1984).
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2,830
Lamotrigine monotherapy (50–200 mg daily) was also reported to be superior to placebo in the treatment of nonrapid cycling bipolar I depression in adults and uncontrolled observations have suggested possible antimanic [19,20], antidepressant [21], and anticycling/mood stabilization properties [13,19,22].
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background
2,831
Size information from the centered and oriented outlines was removed with a uniform scaling of the pseudolandmark configurations to unit centroid size (Benazzi et al., 2011a, b, 2012).
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method
2,832
ation (birth weight, head circumference, crown-heel length, standards of fetal growth according to Lubchenco et al.(6)), and vertical transmission of HIV-1 were determined.
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method
2,833
These models are the radial-modesof-vibration model of Abdullah (1966), the tornado/ boundary interaction model of Tatom et al.
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method
2,834
5 mg), GST-53BP2(715-1005) (1 mg), GST-GL(1-257) (1 mg), and GSTGL(94–257) (1 mg) were separated on duplicate SDS–12.
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background
2,835
Lysine propionylation was recently shown to be abundant in T. thermophilus, an extremely thermophilic Gram-negative bacterium that belongs to the Deinococcus–Thermus phylum (Okanishi et al. 2014).
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2,836
Although the measured values are below the toxic level (Lau and Wong 2000), one should wonder what consequences may derive from an ongoing intake of food packaged in plastic material.
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2,837
Normal FEV1/FVC was defined based on the NHANES III database and the ATS guidelines as values greater than 95% of the predicted for age, gender, and height [1, 10].
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method
2,838
For reference we also include in Table III the results for the scalar field toy model with pure initial data (the s = 0 case) [21,22] (the results for generic initial data coincide with those of gravitational and electromagnetic perturbations).
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result
2,839
50 per extra sample in the pooling strategy to account for personnel time and collection container costs (S1 Text) [6].
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background
2,840
When X(D) ∼ N(μD, σ(2)), the two criteria will have the same optimum, that is, xJ = xC, but the variance of the non-parametric cut-point estimator optimizing the Youden index may be much larger than that of the concordance probability optimizer, Var ( x̂J ) > Var ( x̂C ) [6].
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2,841
There are many studies where CC and cerebral hemisphere widths and areas have been measured on MR images.[13-19]
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2,842
6 shows that if state converges in finite time to the EP, then also the output converges in finite time to the corresponding OEP, however Example 2 in [22] give the conclusion that state converges in fintie time to the EP, but the output does not converge in finite time to the OEP.
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background
2,843
Since then, 164 independent gene losses would have occurred in the lineages, leading to the three present genomes (39).
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background
2,844
Merkel cell virus has been linked to Merkel carcinoma [8] and Fusobacterium has recently been associated with colorectal carcinoma [6].
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background
2,845
Indeed, daily patterns of Epas1 mRNA is rhythmically expressed in the mouse heart with high levels at circadian time 8–12 (unpublished data), which precedes peak expression of mPai-1 mRNA (Minami et al., 2002; Oishi et al., 2005a).
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2,846
This differs from the results of McNaughton (1979), which showed substantial re-growth in grasses after insect feeding.
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result
2,847
2012 (59) Two cohorts; n 7,740 and 4,564 Physical activity and television watching 32 BMI- and obesity-related variants Th e genetic eff ects on BMI were stronger in those with low physical activity or longer hours of television watching Ahmad S, et al.
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2,848
Iontophoretic transdermal deliveries of human insulin and thermoplastic pastes as depot upon cooling have also been tried [18,19].
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2,849
In credit scoring, for instance, applying ensemble techniques can be very effective, but the model is often obliged to have “sound business logic”, that is, to be interpretable [10].
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2,850
…that the approach makes it possible to foster a ‘shared responsibility between students and instructors’ (McLaughlin et al., 2014, p. 242), and overall, optimising classroom time is often specifically emphasised (Gannod et al., 2008; Mason et al., 2013; McLaughlin et al., 2014; Tucker, 2012).
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background
2,851
A recent storytelling task by Hendriks et al. (2014) confirmed this overall pattern but also highlighted that other factors can modulate this effect of the discourse stages. In the task used by Hendriks et al. (2014), participants were asked to tell picturebased stories featuring two characters of the same gender to a hypothetical listener.
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2,852
In addition, education is likely to enhance female autonomy so that women develop greater confidence and capabilities to make decisions regarding their children’s health [39].
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background
2,853
Another group reported that the 118T9 10 repeat was associated with higher reporter gene expression in HepG2 liver cells (Yamanaka et al., 2004), and this variant was recently linked to higher incidence toxicity and increased response to irinotecan in cancer patients.
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background
2,854
These devices have also been clinically recommended for stabilization and modulation of the load distribution across mildly degenerated discs in an attempt to alleviate discogenic back pain and potentially enable regeneration of disc cells [22, 23].
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2,855
A more formal study of incidence and the histology of the tumors need to be done, but these results suggest thatMuSKantibodies are not so infrequent in Chinese as previously reported in a study from Taiwan [5].
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2,856
…orogenic events have contributed to shaping the current diversity and distribution of modern species in both the Neotropical (Bush 1994; Hoorn et al. 1995, 2010; Pennington et al. 2004; Rull 2006, 2008, 2011; Antonelli & Sanmartin 2011) and temperate regions (Ruzzante et al. 2006,…
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2,857
It is well-known that a single nick (SN) does not efficiently induce gene editing (Ran et al. 2013a; Davis and Maizels 2014).
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2,858
, ABA) mediate priming of guard cell Ca2þ sensors, such that they can respond to elevated cytosolic Ca2þ levels [63].
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background
2,859
Findings reported by Bryzgalova et al (194), suggesting reduced total GLUT4 levels in muscle as an underlying cause of the ER KO insulin resistance phenotype, were not supported by data from Ribas et al (192).
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method
2,860
Beside SecuGen Hamster IV, other optical devices were used to collect the IIIT-D Multisensor Optical and Latent Fingerprint [25].
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method
2,861
This corresponds to T191 of tobacco CYC3;3, a extremely conserved site important for full CYCD nuclear import (Menges et al. 2007).
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2,862
Aside from the effects on Th1 cells, IL-27 has recently reported that played a regulatory role in limiting excessive inflammation during infection with Toxoplasma gondii by modulating the development of Th17 cells (20, 21).
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2,863
The Metropolis- Hastings algorithm [49] was used to estimate the posterior distributions for ancestral reconstructions and model parameters in a Markovchain Monte Carlo framework [29].
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method
2,864
This assumption is confirmed by the different pattern of the expression of X linked genes in different parts of the same placenta: equally probable, mostly from one homolog, and fully monoallelic (Moreira de Mello et al., 2010).
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background
2,865
The OHC lateral wall, where the motor elements are located [24,31], was modeled as a series mixture of passive ‘‘elastic’’ and active piezoelectric ‘‘motor’’ elements [29] to arrive at a composite constitutive model for the lateral wall.
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2,866
Plan and goal recognition models have been devised for story understanding systems (Charniak and Goldman, 1993), productivity software (Horvitz, et al., 1998), intelligent tutoring systems (Conati, Gertner, and VanLehn, 2002), and dialogue systems (Blaylock and Allen, 2003).
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background
2,867
While Hutt and Longtin (2010) chose pi=pe, reflecting equal affinity of propofol for GABAA receptors located on cortical inhibitory and pyramidal neurons, we relax this assumption, thereby accounting for the possibly differential affinity of propofol for different neuron types.
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2,868
[31], we check their validity in the case of charged Higgs boson production.
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background
2,869
The Intercontinental Chemical Transport Experiment B (INTEX-B) aircraft campaign over the North Pacific and western coast of North America made measurements of OH and HO2 (Mao et al., 2009; Singh et al., 2009).
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2,870
The Swi1-Swi3 complex or its homologues are known to facilitate the loading of Mrc1 or Claspin onto chromatin (8, 41).
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2,871
To measure the effect of verb type on the observed QUDs, we used mixed-effect logistic regressions (Jaeger, 2008).
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method
2,872
Similar to our results, concentrations of 3.15 ngmL 1, 31.5 ngmL 1 and 315 ngmL 1 of progesterone added during the culture phase of bovine in vitroproduced embryos did not impact on the proportion of zygotes reaching the blastocyst stage in a recent study (Clemente et al. 2009).
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result
2,873
, 2012; Bergen et al., 2012) but also for studying children’s pragmatic abilities without implicitly assuming they have mastered challenging linguistic structures (Stiller et al., 2011). In this paper, we extend these results beyond simple reference games to full decision-problems in which the agents reason about language and action together over time. To do this, we use the Decentralized Partially Observable Markov Decision Process (Dec-POMDP) to implement agents that are capable of manipulating the multiply-nested belief structures required for implicature calculation. Optimal decision making in Dec-POMDPs is NEXP complete, so we employ the single-agent POMDP approximation of Vogel et al. (2013). We show that agents in the Dec-POMDP reach implicature-rich interpretations simply as a byproduct of the way they reason about each other to maximize joint utility.
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method
2,874
Data-centric storage (DCS) [24,27,42,56] provides in-network storage and query mechanisms for sensor networks.
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2,875
In addition, a new flgII-28 region distinct from flg22 in the flagellin of Pseudomonas syringae pv. tomato (Pst) has been recently characterized as a MAMP, which may be specifically recognized by Solanaceae species (Cai et al., 2011; Clarke et al., 2013).
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2,876
…recent reports have implicated CHH as a regulator of multiple physiological effects, which include reproduction (De Kleijn and Van Herp, 1998; Khayat et al., 1998), molting (Chung et al., 1999), osmoregulation (Serrano et al., 2003; Spanings-Pierrot et al., 2000), and lipid metabolism…
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2,877
IL7 and IL15 are IL-2 family cytokines regulating survival and activation of lymphocytes, and are of interest in MS research since they signal through the IL2- and IL7-receptors, which have shown strong association with MS in genome-wide association studies [31].
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2,878
Our new scoring function estimates the penalty term from the data to make it consistent with the data, which is similar to the DIC (Deviance Information Criterion) score trying to identify models that best explain the observed data [30].
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method
2,879
Crystal structures of some theta GSTs have indicated that the GSH-binding site may be sited further inside the protein than in other classes of GST, and that conventional GSH-aYnity matrices may be unable to bind the active site (Hayes and Pulford, 1995).
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2,880
This is a particularly positive result as OASIS mainly serves the area of South London that is socioeconomically deprived, has a high proportion of ethnic minorities and an often difficult relationship between service users and mental health services (Broome et al. 2005).
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2,881
Other studies indicate that methyl salicylate (MeSA) azelaic acid (AA), glycerol-3-phospate (G3P)derived factor, and dehydroabietinal (DA) may also be SAR long distance signals (Park et al., 2007; Vlot et al., 2008; Jung et al., 2009; Chanda et al., 2011; Chaturvedi et al., 2012).
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2,882
In Marsupenaeus japonicas and Penaeus semisulcatus, the CHH from eyestalk is involved in the suppression of vitellogenin (Vg) gene expression (Khayat et al., 1998; Tsutsui et al., 2005).
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2,883
In this respect, we have recently shown that malignant transformation causes losses, gains, and imbalances in the expression of human MHC I and two antigen-processing gene products: the endoplasmic reticulum (ER) aminopeptidases ERAP1 and ERAP2 (13, 14).
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2,884
In addition, differential hypertrophy occurs even within a single muscle along its length (Narici et al., 1989, 1996; Housh et al., 1992).
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2,885
The resulting levels of ChE in plasma were in the same order of magnitude as those found by Winters et al. (1997) in control rabbits.
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2,886
…impact on overall energy cost. the Ec of the uphill sections we found can be compared with the results of other studies (table 2). the lowest Ec (tosi et al. 2009) was described for a short section lasting only 8 min while that of races lasting 1–2 h (Duc et al. 2011) up to 6 h 45 (this…
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2,887
Ruby [4, 10] goes one step further by making the syntax much more compact and simpler and also provides various built-in features that make the common tasks of text processing, creating and processing threads, web programming etc.
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2,888
[31] with the same significance, we still find sufficient evidence that F = 4 is favourable in many
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2,889
Optimization We used three objective functions that were employed previously to study multi-finger prehension in human performers (Hershkovitz et al. 1995, 1997; Zatsiorsky et al. 2002b; Pataky et al. 2004a, b).
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method
2,890
We have proposed that the highly specialized EOM allotype is a consequence of a novel myoblast lineage interacting with extrinsic factors during a postnatal critical period of development (5, 7, 12, 57).
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2,891
Examples of possible modifiers include loci encoding xenobiotic enzymes, NAT1, NAT2, GSTM1, GSTT1 (7–9), or ATM, ataxia-telangiectasia-associated locus (10).
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2,892
…a homologous exchange mutant of the Er. carotovora subsp. carotovora rpoS gene, the suicide vector pUT mini-Tn5 Cm was used. pUT mini-Tn5 Cm carries the λpir-dependent R6K ori, which does not replicate in bacteria that lack λpir, such as Er. carotovora subsp. carotovora (de Lorenzo & Timmis, 1994).
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2,893
Furthermore, we combined learning rate annealing with embedding batch normalization, the latter of which has been proven to help the model train faster and allow faster learning [1].
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method
2,894
The cortical lesions resulted in significantly smaller cells in the medial geniculate nucleus (MGN) in early-lesioned male, but not female rodents (Herman et al., 1997).
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2,895
The tool differs primarily from the original CHLT-30 in that a Bdon’t know^ (DK) response option was included for each item because in pilot testing of the instrument, respondents did not feel comfortable guessing and preferred to indicate they did not know [25].
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method
2,896
As an example, it has recently been demonstrated that one or two strains are sufficient to drive major changes in gastrointestinal and host (mouse) metabolic profiles, where up to 1012 microbial cells or 4500 species may coexist (Marcobal et al., 2013).
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2,897
4A, compare lanes 1 to 2), confirming previous studies that demonstrate HCMV infection results for both NF B activation and DNA binding activity (18, 21, 23, 61).
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result
2,898
Due to the insufficient oxygen supply through the surface air and the plant-mediated oxygen transfer, incomplete nitrification has been reported in CWs (Tanner and Kadlec, 2003; Huett et al., 2005).
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background
2,899
Introduction of HDAC4-specific siRNA significantly inhibited denervation-induced atrophy (Fig- ure 1A) as was also shown previously (Moresi et al., 2010).
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method