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1,900
Ten Caucasian patients with grossly increased levels of N-isovalerylglycine and N-isovalerylcarnitine were diagnosed with IVA and the metadata on these cases are described in Dercksen et al. 2012.
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background
1,901
The in-vitro blue-plaque-forming assay was performed to observe the competitive inhibition effect of CCR5 mimic peptides with its phage counterparts [17].
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method
1,902
The second approach involves an integrated network of services that work in partnership to connect and refer women to the appropriate provider [74], such as case management [71,77,79,80].
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background
1,903
We evaluated four SNPs in DICER, DROSHA, XPO5, and RAN, which are essential for miRNA biogenesis [26,27].
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method
1,904
…and central VTA) (Valenti et al., 2012; Lammel et al., 2012), whereas short-term stress or other different chronic stressors (e.g., repeated intermittent stress) (Shaham et al., 2000 & 2003) may increase activity of these cells (Moore et al., 2001, Valenti et al., 2011, Valenti et al., 2012).
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background
1,905
Enock et al. (2014) found that both groups had very unreliable (near 0) dot probe bias scores initially and in the first week of ABM.
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background
1,906
Nevertheless, one area of ethics for HTA that indeed is considerably underdeveloped in comparison to other areas of HTA is quality assessment of ethics analyses in HTA [10], [11].
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background
1,907
FUS dC is Partially Co-localized with PRMT1 in the Cytoplasmic Inclusions FUS/TLS encodes 526 amino acid protein, characterized by N-terminal QGSY region, G-rich domain, RRM (RNA recognition motif), two RGG (Arg-Gly-Gly repeats), and Cterminal non-classical NLS (514-526 aa) [8,14] (Fig.
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background
1,908
…methods rely on some additional and often heuristic step to generate an initial solution, such as adversarially-trained neural networks [Conneau et al., 2018, Zhang et al., 2017a,b], robust self-learning [Artetxe et al., 2018b] or 5This can be easily verified by noting that the…
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method
1,909
rentiation in hMSCs The C2 domain of PKCη is thought not to affect substrate-specificity of the kinase but instead aid in its localization to membranous systems (Littler et al., 2006).
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background
1,910
In previous studies, we found a strong correlation between chemokine and cytokine mRNA and protein levels [27, 28].
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background
1,911
Such multiorientation representations can be made using various techniques, such as invertible orientation scores (which is obtained via a coherent state transform) [3,30,11,36, 40,6], continuous wavelet transforms [28,30,61,11], orientation lifts [65,14], or orientation channel representations [35].
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method
1,912
In order to analyse victimization the Screener Sum Version [20] was used to compute total victimization reports on the
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method
1,913
…recognizing mammalian homologs of katanin also recognize large microtubule-dependent structures surrounding γ-tubulin foci at spindle poles in several cell types and, in addition, recognize a smaller microtubule-independent focus at the centrosome in some cell types (McNally and Thomas, 1998).
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background
1,914
Details regarding the study design and characteristics of the study participants have been published elsewhere [17].
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background
1,915
The oils, which are generally composed of complex mixtures of monoterpenes, phenols, and sesquiterpenes, have demonstrated insecticidal, repellent, antifeedant and insect growth regulatory properties, and suppression of adult insect fertility and oviposition [4,6].
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background
1,916
…may exist between slow freezing and vitrification protocols, since vitrified whole sheep ovaries in contrast to slow frozen ovaries contained substantially reduced numbers of primordial follicles and blood vessels with some degree of damage (Courbiere et al., 2005, 2006; Baudot et al., 2007).
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background
1,917
Besides, the cys eine-male mide linkages are instable in a circulator syst , because the maleimide-linker reaction can be exchanged by the active th ol group of cysteine in human serum, resulting in the premature release of toxin before internalization [7].
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background
1,918
Rac plays important roles in the activation of NOX1, NOX2, and c-Src (11, 23, 24, 28).
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background
1,919
However, they are very unstable in all other situations, namely, in simulations of GQs lacking the channel ions (54,60), in G-triplexes even in excess salt conditions (61) and in isolation (the present work).
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background
1,920
5mW/cm power of UV365 for 30min to obtain cell sheets from the TN and TR surface [13].
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method
1,921
This can be readily observed when selection is artificially induced by forcing GC B cell-T follicular helper (Tfh) cell interactions (Gitlin et al., 2015; Gitlin et al., 2014; Victora et al., 2010), but is also likely to be at the origin of the ‘‘clonal bursts’’ that can lead to radical loss of clonal diversity in GCs under unmanipulated conditions (Tas et al.
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background
1,922
…2010; Heilman and Smith, 2010), slotfilling with question templates (Popowich and Winne, 2013; Chali and Golestanirad, 2016; Labutov et al., 2015), or implicitly modeled by recent neural models(Du et al., 2017; Zhou et al., 2017b; Yuan et al., 2017; Song et al., 2017; Subramanian et al., 2017).
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background
1,923
Elevated blood pH is consistent with one reported result (56) but differs from most other studies in which pH of hibernating and euthermic ground squirrels do not differ (15, 16, 27, 29, 40).
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result
1,924
But societal readiness also impacts on public and patient readiness, so it addressed the issue of accessibility to e-health innovations by the public and patients as well.(3,11,18) Also, core readiness addressed components of organisational readiness and healthcare provider 1830 articles and links identified from electronic databases
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background
1,925
(vii) Multiple subcellular locations enable the same protein to exert different functions in different parts of the cell [18].
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background
1,926
Only the learning trials of the CVLT2 and BVMTR were administered, in accordance with BICAMS opinion paper (Langdon et al., 2012).
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method
1,927
Nevertheless, recent reports have implicated CHH as a regulator of multiple physiological effects, which include reproduction (De Kleijn and Van Herp, 1998; Khayat et al., 1998), molting (Chung et al.
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background
1,928
The current results in healthy participants also align well with studies showing impaired value-based decision-making across substance-use disorders (Lubman et al, 2009; Paulus, 2007) and with the growing evidence for dysregulation of MOR function across addictions (Ghitza et al, 2010; Mick et al, 2015).
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result
1,929
Network-based studies gave rise to the disease module hypothesis (Barabási et al 2011; Vidal et al 2011) where diseases with an overlap in biological networks show significant symptom similarity and common disease mechanisms, whereas diseases residing in separated network neighborhoods are…
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background
1,930
For example, collagen fibers lack proper organization in the skin and tendons of TSP2-null mice, with underlying fibrils being loosely packed with larger than normal diameters and nonuniform cross-sections (Bornstein et al., 2000; Kyriakides et al., 1998).
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background
1,931
Our model is a further development of the previous remarkably detailed model by Halter and Clark (1991) in which the separation of the axonal membrane, myelin sheath and the corresponding compartments was first reported in the literature.
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method
1,932
Probes EUB338 I-III (Amann et al., 1990; Daims et al., 1999) for the domain Bacteria and Gam42a with competitor (Manz et al.
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background
1,933
The demonstrated modulators were based on either a MOS capacitor [7], a forward-biased p-i-n diode [8-9], or a reversebiased pn junction [10-14].
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method
1,934
The genotype frequencies of RAN rs14035 and XPO5 rs11077 in the control group of our study showed similar patterns to the results in the control groups of previous reports regarding lung cancer and breast cancer in Korea [26,27].
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result
1,935
U-box domain does not depend on zinc binding to keep its stability, but have evolved instead networks of hydrogen bonds and salt bridges formed by the corresponding residues at metal ligand positions (Hatakeyama et al., 2001; Nordquist et al., 2010; Wiborg et al., 2008).
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background
1,936
We also assess the rate of convergence of the OFO algorithm in a pure online learning setup.3 The online learner A in OFO was implemented in different ways, using Logistic Regression (LOGREG), the classical Perceptron algorithm (PERCEPTRON) [13] and an online linear SVM called PEGASOS [14].
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method
1,937
…represent a range of efficacy: morphine (intermediate efficacy), buprenorphine (relatively low efficacy), and etorphine (relatively high efficacy) (Emmerson et al. 1996; Selley et al. 1998) on the hot-plate and tail-flick tests under conditions previously described (Paronis and Holtzman 1991;…
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background
1,938
The model was generated on the basis of the kinetics data in Figure 1 and Figure S2, previously reported kinetics data [17,18], and a crystal structure study of the ATP-RT complex [11].
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method
1,939
There are some exact [6, 4] and population based approaches [7] for finding the bulge knee.
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background
1,940
(3) The maximum diameter of the postoperative cavity was greater than 15 mm [14] for avoiding of partial volume effect when measuring, such as adjacent cerebrospinal fluid, the parenchyma FLAIR high signal intensity surrounding the cavity, as well as vessels, etc.
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background
1,941
, 2005); others indicate that, byactivating Jak/STATindependent pathways, IFN-γ induces the nuclear translocation of both NF-κB and IRF-1 (Kim et al., 2004; Park et al., 2005).
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background
1,942
The SNF1 gene (also known as CCR1 or CAT1) is essential for derepression of these genes [3–5], and sequencing and expression studies have revealed that SNF1 encodes a protein kinase [6].
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background
1,943
To construct the wild-type strain containing the plasmid pCap1GFP [24], the plasmid was transformed into DAY1, obtaining the strain DAY1 ? pCap1-GFP.
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background
1,944
The results of Todd et al. (2004) also show that there is a very high correlation between the ground truth and the adjusted depth of the near and far points for all the orientations of the planar cuts.
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background
1,945
95 USD) per capita in 2010 based on survey in 17 sample centers and model estimation [31].
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background
1,946
(9) have demonstrated an almost complete inhibition of ROI production in mice null deficient for PKC .
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background
1,947
Our results show that dynein arms are apparently intact after elastase treatment, whereas trypsin induces fragmentation of the HCs, as has previously been reported (Ogawa, 1973; Ow et al., 1987; Inaba, 2000).
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result
1,948
DRS scores as reported were adjusted for participant age and education (Age and Education Corrected Moan’s Scaled Score, or “AEMSS”; according to the DRS reference manual; www.psychassessments.com).
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method
1,949
This result was in accordance with the findings that oxidation could impair water-binding in meat (Huff-Lonergan and Lonergan, 2005; Morzel et al., 2006).
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result
1,950
…Comparative algorithms Most of exiting dynamic evolutionary algorithms were applied to moving peaks benchmark problem (MPB) (Mendes and Mohais 2005; Bui et al. 2005; Blackwell and Branke 2006; Moser and Hendtlass 2007; Woldesenbet and Yen 2009; Daneshyari and Yen 2011; Li and Yang 2012; Sharifi et…
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method
1,951
[10] present the obstruction-free step complexity which is the maximum number of steps that an operation needs to perform if no other processes are taking steps.
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background
1,952
For example, the design in [103] uses a 1 bit counter in each pixel and reaches a dynamic range of 90 dB when operated at high speed.
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background
1,953
Accumulating evidence indicates that NSAIDs have pleiotropic effects in many cell types, and therefore may have a therapeutic role in several conditions including prevention and treatment of certain types of cancer,([36]) and in prevention and treatment of neurodegenerative diseases, such as Alzheimer disease.([22]) It has been demonstrated previously that Ibuprofen, as well as other NSAIDs, activate PPARγ in several cell types.
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background
1,954
…dual tasking adversely affects multiple aspects of gait in patients with PD and in older adult idiopathic fallers (i.e., those elderly who fall without any clear reason) (Bond and Morris 2000; Camicioli et al. 1998; O’Shea et al. 2002; Yogev et al. 2005; Springer et al. 2006; Bloem et al. 2001).
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background
1,955
Northern blotting The ORF sequence for HvNAS1 (AB010086) was used to create an HvNAS1 probe (Suzuki et al. 2006).
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method
1,956
…H0) between monospecific and mixed patches were assumed when the 95 % confidence intervals did not overlap 100 samples (Badano and Cavieres 2006); when the number of samples was less than 100, we used the extrapolation routine proposed by Colwell et al. (2012) to obtain S0 and H0 to 100 samples.
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method
1,957
These effects of locomotion on the baseline activity of Sst interneurons confirm some previous results (Polack et al., 2013) but they appear to disagree with other measurements (Fu et al., 2014).
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result
1,958
Similarly, we chose not to estimate demand using the method laid out by Davis [5] due to potentially confounding instances when neighbours increase water availability as seen in studies of facilitation [37].
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method
1,959
Moreover, CNT have a great pollutant adsorption capacity and may in the future be explored for bioremediation purposes [33-38,53,65-72].
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background
1,960
For example, the contributions of the EGF and HRG bound HER1HER3 dimer to the EGFR and HER3 phosphorylation signals at the cell surface are respectively expressed as [R13EHs]*pf13ehs and [R13EHs]*pf31ehs where [R13EHs] is the dimer abundance and pf13ehs and pf31ehs are cell surface phosphorylation factors.
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method
1,961
These results are in accordance with observations made for translocation of Foxo3a from the nuclei of oocytes during follicle activation of mice and pigs (Castrillon et al., 2003; Ding et al., 2010) but differs for Foxo3a immunodetection in pre-granulosa cells from primordial follicles of other species (Tarnawa et al.
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result
1,962
For bji in (16) represents the interference from the other D2D pairs that share spectrum resources with user j and user i [9].
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background
1,963
FREAD was applied to model the missing loops [49], and finally, I-TASSER was applied to model all the rest missing residues [50].
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method
1,964
5-HT-evoked currents recorded from outside-out patches excised fromHEK-293 cells expressing WT 5-HT3A receptors resemble miniature whole cell currents with no discernible unitary events (3, 5, 7).
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background
1,965
Vol. 74, Nr. 9, 2009—JOURNAL OF FOOD SCIENCE E537 E:Food Engineering & PhysicalProperties Synchronous spectroscopy of meat . . . well with the characteristics of tryptophan fluorescence spectra (Boubellouta and Dufour 2008), which is present in meat proteins.
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background
1,966
Some of the reasons for the discrepancies include lateral and elevational motion (Kallel et al. 1997) and frequencydependent attenuation (Varghese and Ophir 1997c), low SNRs, nonhomogeneity of the phantoms, and nonuniform compression.
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background
1,967
play a role in proper preprocambium formation (Carland et al., 1999; Carland and Nelson, 2004).
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background
1,968
out mainly in rural areas of Tenerife [2], along with the high prevalence of P.
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background
1,969
Whether Arctic clouds have a net warming or cooling effect depends on the time of year and location (Garrett et al., 2002; Garrett and Zhao, 2006; Lubin and Vogelmann, 2007; Sedlar et al., 2010; Shupe and Intrieri, 2004; Tjernström, 2005; Wang and Key, 2003).
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background
1,970
Unitarymicroscopic currents are too small to be directly resolved using conventional electrophysiological recording techniques (3).
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background
1,971
014-inch guidewire as described (14,15); 2) after the wire connected the 2 large blood vessels, we implanted a covered stent (“endograft”) to bridge the 2 vessels; and 3) BMS anchoring was used as an SVC end-to-end anastomosis landing zone and to secure the right PA end-to-side anastomosis.
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method
1,972
8-kb human COX-2 cDNA containing the entire coding region of human COX-2 was inserted into the first exon of the human growth hormone gene controlled by the mouse albumin enhancer/promoter (14, 15).
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method
1,973
The leader appears to promote transcription towards the repeats (Brouns et al., 2008; Hale et al., 2008; Lillestøl et al., 2006, 2009; Marraffini & Sontheimer, 2008), generating the RNAs that constitute the molecular base of the interference action (Brouns et al.
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background
1,974
The results of behavioral analyses are consistent with published data reporting that the Ts65Dn mice show normal or hyperactive exploration in the open filed (Coussons-Read and Crnic, 1996; Martínez-Cué et al., 2002; Faizi et al., 2011; Incerti et al., 2011).
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result
1,975
This may include looking for signs that are more prevalent in malignant cases, such as feeder vessels, gelatinous appearance and leukoplakia [Figure 1].[8,18] These signs as well as others could be used to help develop a diagnostic algorithm, as proposed by Nguena et al, to help clinicians identify OSSN and know when to appropriately refer for more specialized care.
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background
1,976
These included a shortened version of the Extended Mental State Exam [25] (SF-EMSE), letter cancellation task [26] as used in the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) [27], Hopkins Verbal Learning Test (HVLT) [28], Cambridge Neuropsychological Test Automated Battery Paired Associates Learning Test (CANTAB-PAL) [29-31], Visual Sensitivity Test (VST) to assess visual impairment deficits contributing to cognitive impairment [32] Short National Adult Reading Test (Short-NART) [33] and a test for prospective memory (also as described in MRC CFAS) [34].
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method
1,977
This negative correlation, such that more positive mean PBR occurred concurrently with a more negative mean NBR, is in agreement with previous studies (Klingner et al., 2010; Shmuel et al., 2002), suggesting that the magnitude of ipsilateral inhibition increases with the magnitude of increasing contralateral excitation.
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result
1,978
…amount of antibiotics in wastewater and/or in ponds by fish farmers without regulations and/or in agriculture These finding are similar to those of (Kusuda and Sugiyama, 1981) who showed that Staphylococcus epidermidis which present in the aquatic environment originated from water (or fish) rather…
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result
1,979
Thus, in HEK293 cells, FGF23 and FGF2 activate distinct FGFR adaptor proteins, which could explain their differential downstream signaling in cardiac myocytes (Faul et al., 2011).
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background
1,980
It was suggested that the protective and rescue effect of ( )-deprenyl is unrelated to the inhibition of MAO-B enzyme activity (Finnegan, 1990; Ansari et al., 1993).
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background
1,981
The concept of functional repair was first introduced by Burkhart and colleagues in the early 1990’s [2,16-18].
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background
1,982
There are various reports regarding tobacco consumption from different parts of India, i.e., 1.9% in New Delhi to 75% in Mizoram;[8] the total prevalence of tobacco consumption in the present study was found to be 48.8% [Table 1], this finding is significantly higher than the reports of Global Youth Tobacco Survey (GYTS) 2009 (14.6%),[3] 2006 (13.7%),[1] and 2003 (16.9%).
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result
1,983
Quantification of the α-subunit of H,K-ATPase exhibits a characteristic translocation typically seen in histamine-stimulated secreting parietal cells (11,18).
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background
1,984
This prompts speculation that non-neuronal defects observed following exposure to chemical AChE inhibitors reflect off-target effects (Behra et al., 2004) or that in vitro morphogenetic functions of AChE are irrelevant/redundant in vivo (Cousin et al., 2005; Johnson et al., 2008b).
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background
1,985
This concurs with previous studies which have addressed this question (40, 53), the results of which have piqued the idea that estrogen receptor b, expressed in lung cancer cells, may be causal to this observation (54, 55), though various other hypotheses have also been suggested (56).
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result
1,986
We assessed participants’ dehumanization of Arabs by using the Ascent scale of blatant dehumanization (Kteily et al., 2015).
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background
1,987
As ectotherms, they are active and feed during the cooler times of the day, usually from dawn until mid-morning and from mid-afternoon until dusk [39], [40], [41].
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background
1,988
when there is an expectation of a reward than on trials when there is none (Murray et al. 2008; Pessiglione et al. 2006), reflecting an increased motivation to obtain rewards.
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background
1,989
Currently, high-throughput methods to screen high-producer cells have been developed [48, 49]; including automated systems such as colony picking and the Cello systems [50].
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method
1,990
Pd of turtles and lizards also have Enk-IR neurons and has a peculiar, very dense, Enk-IR-containing terminal area in its core (our data, [47, 67].
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background
1,991
Hybridization, normalization, and signal acquisition were performed as previously described according to the Affymetrix protocol (23, 33).
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method
1,992
All speech was recorded using a head-mounted microphone while the participants were connected to a Finometer [4], a device that enables continuous monitoring of CV parameters in a non-intrusive manner, i.e., by using a finger-cuff.
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method
1,993
We augment phrase tables only with synthetic phrases that capture simulated ASR errors, the methodology that we advocate, however, is applicable to many problems in translation (Tsvetkov et al., 2013a; Ammar et al., 2013; Chahuneau et al., 2013).
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method
1,994
A constant-phase model (25) was employed to compute Raw (“Raw-FOT”), in addition to tissue resistance (Gti) and elastance (Hti) coefficients.
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method
1,995
…fabric is a quasiperiodic fabric with a small (1–5 km) characteristic wavelength, and hence arises from deformation of a layer of smaller effective mechanical thickness than the longer-wavelength (5 to >30 km) folds [Hansen and Willis, 1996, 1998; Phillips and Hansen, 1998; Ghent and Hansen, 1999].
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background
1,996
The presence of such micro-cracks provides a potent site for fatigue cracks to nucleate under high-cycle fatigue loading (Peters et al., 2000, 2002).
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background
1,997
Indeed, compounds such as methyl benzene, ethylbenzene, 1-octene, xylenes, styrene and 1,4 dichlorobenzene have been found in packaged food (Lau and Wong 2000; Nerì et al. 2002).
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background
1,998
We compare our full algorithm to several variants, along with recent [2] and concurrent work [23].
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method
1,999
Overall survival (OS) and progression-free survival (PFS) were measured from the date of diagnosis and were estimated according to the Kaplan-Meier method[21].
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method