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1,400
Peripheral nerve disease is a chronic complication of human and experimental diabetes (30) that may confound observational or quantitative measurements of evoked motor responses.
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background
1,401
FGFR4 Blockade Attenuates LVH in the 5/6 Nephrectomy Rat Model of CKD We tested the therapeutic potential of interfering with cardiac FGF23-FGFR4 signaling in the 5/6 nephrectomy rat model of CKD that develops increased FGF23 levels, severe hypertension, and LVH within 14 days after nephrectomy (Faul et al., 2011).
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background
1,402
…allowing the device to include a range of features (e.g. digital compasses, accelerometers, gyroscopes and light meters), to act as global positioning (GPS) receivers, and to run software that processes geospatial information in ways comparable to more expensive computing devices (Kwok 2009).
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method
1,403
In addition, sequences homologous to the cao-2 (Saelices et al. 2007) and ylo-1 (Estrada et al. 2008) genes for the Wnal steps to neurosporene are present in the sequenced genome from P. anserina (Espagne et al. 2008).
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background
1,404
On the morning of the infusion day, catheters were placed percutaneously into one tail vein and one tail artery under local lidocaine anaesthesia [16], and the tail was then secured as described above.
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method
1,405
CRISPs are single-polypeptide proteins with molecular weights of ;20 to 30 kDa (Yamazaki and Morita 2004, 2007) and are known to have a high degree of amino acid sequence similarity and a highly conserved specific pattern of 16 cysteine residues.
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background
1,406
For all in vivo measurements of protein synthesis with SUnSET (Goodman et al., 2011b), puromycin solution was prepared by diluting the appropriate volume of the stock solution that was needed to inject micewith 0.04 µmol/g body weight in 200 µl of PBS, and subsequently administered into the animals…
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method
1,407
In the context of stream joins, this is usually done by selectively dropping some of the input tuples or selectively processing only a subset of the join windows [3,9,13].
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method
1,408
26 Finally, Gillingham and Tsvetanov (2017) provide support for their assumption of static demand using data on purchases and a consumer survey in the residential solar market in Connecticut, in the United States.
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background
1,409
In addition, the MMSE [16], the Geriatric Depression Scale (GDS) [35] and Spielberger’s State-Trait Anxiety Inventory [26] were administered to assess mental state.
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method
1,410
4.2 the COLD-Saarb dataset is concisely described, while detailed information can be found in (Ullah et al 2008).
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background
1,411
Surface staining for flow cytometry was performed by standard techniques (Johnston et al., 2009) and the following clones: CD4 (RM4-5), CD45.
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method
1,412
The importance of Lcarnitine in improving oocyte quality and reproductive performance has been demonstrated in animal and human studies [19-24].
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background
1,413
persistence of previously unknown parasite strains in populations that are severely affected by HIV-1 (Pieniazek et al. 1999; Gramiccia, 2003; Pratlong et al. 2003).
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background
1,414
Based upon this review of slides, cases were assembled into three case-series representing progressively more stringent de®nitions of OED, the most restrictive of which required that both blinded pathologists diagnose the case as having OED [8].
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method
1,415
…0.1-1 µg/ml IgG) followed by fluorescent secondary antibody, both diluted in 4% BSA in TBST. α-Tubulin was detected with mouse monoclonal DM1α (Sigma Chemical Co, St Louis, MO). p60 katanin was detected with an affinity-purified anti-human p60 rabbit polyclonal antibody (McNally and Thomas, 1998).
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method
1,416
For amplification of over 500 bp of rpoB, primers (rpobF, rpoBR, rpoBF2 and rpoBR2) and PCR cycling conditions described by Rajaniemi et al. (2005) were used.
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method
1,417
A poor performance on the FCSRT has also shown a high correlation with atrophy in the medial temporal lobe (Sánchez-Benavides et al., 2010; Sarazin et al., 2010), and was significantly associated with cerebrospinal fluid ADbiomarkers (Rami et al., 2011; Wagner et al., 2012).
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background
1,418
The SUM1315 cell line was purchased from Asterand (Detroit, MI, USA) in 2009 and cultured as in [17] from freeze downs from 2009.
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method
1,419
…eVects of gravity The results of this experiment are consistent with the hypothesis that human observers apply a simpliWed model of gravity when predicting the vertical movements of an object (McIntyre et al. 2001; Senot et al. 2005; Zago and Lacquaniti 2005; Zago et al. 2004, 2005, 2008, 2009).
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result
1,420
A few years ago, a kinetic model was proposed for the glucosidase II alpha subunit (1, 3).
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background
1,421
Maxout MLP has previously been proven as a universal approximator [7], wherein a maxout unit is implemented by the following function:
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background
1,422
We choose InferSent because it performed competitively with the best-scoring systems on the Stanford Natural Language Inference (SNLI) dataset (Bowman et al., 2015), while being representative of the types of neural architectures commonly used for NLI tasks.
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method
1,423
EF was assessed using the Behavior Rating of Executive Function – SelfReport (BRIEF-SR; Guy et al. 2004), the Wisconsin Card Sorting Test Computerized Version 4 (WCST-CV4), and five computerized tasks: Go/No-Go, Anti-Saccade Arrows Task, Task Switching, the Flanker Task, and Shape Matching (Friedman and Miyake 2004; Nigg 2000; Rogers and Monsell 1995).
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method
1,424
Different mechanisms of resistance to CDDP have been described, including reduced intracellular accumulation of CDDP; increased detoxification of CDDP by the thiols, glutathione and metallothionein; increased DNA-repair activity; and increased tolerance to DNA damage (Galluzzi et al. 2012; Kelland 2007).
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1,425
Either explanation (DIR1 dimers or DIR1-protein complexes) fits with the appearance of trypsin-sensitive high molecular weight fractions in dehydroabietinal-elicited SAR observed by Chaturvedi et al. (2012).
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1,426
Similar results were reported by Lima et al. (2011) when using fruit extracts, and by NazaÃÅrio (2011), when using extracts from recalcitrant seeds of the palm tree Bactris gasipaes.
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result
1,427
The type species, Aedes aegypti densonucleosisvirus (AaeDNV) genome encodes two overlapping ORFs the nonstructural proteins, NS1 and NS2 (Afanasiev et al., 1991).
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background
1,428
We computed texture features that have been shown in previous studies with mammograms to distinguish the parenchymal patterns of women at different risk levels [2, 3].
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method
1,429
Our fieldwork included hands-on participation in maker projects, drawing from methods such as research through design and critical making [5, 51, 71].
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method
1,430
While azoospermia is common in males with isodicentric Y chromosome, our understanding of the cause of spermatogenic failure is clear only for those idic Yp patients with breakpoints that occur along the Yq and typically result in AZF deletion and/or recombination [12, 13].
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background
1,431
Our results are also consistent with those of recent studies of how experimentally conditioned aversive stimuli inhibit instrumental approach behavior (Geurts et al., 2013; Huys et al., 2011), which have been modeled as competing valuation systems in RL models (Dayan et al., 2006; Guitart-Masip et al., 2012, 2014; Huys et al., 2011).
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result
1,432
In this paper, the RP of LC is obtained by using the calculation method given in our published manuscripts [20, 21].
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method
1,433
In that study, they concluded that the error probability of each option was dependent on its position in the interface (the same conclusions were obtained in Velasco-Álvarez & Ron-Angevin, 2009).
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method
1,434
For bladder cancer, clinical studies yielded conflicting results on the cancer prevention effects of statins in patients with bladder cancer [8–10].
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result
1,435
…NMJ is regulated by factors intrinsic to the motor neuron, including proteins that regulate intracellular signaling, as well as retrograde signals that convey postsynaptic activity levels to modulate neuronal properties (Collins and DiAntonio, 2007; Harris and Littleton, 2015; Menon et al., 2013).
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background
1,436
This is in agreement with adult studies indicating elevated proportions of saturated fatty acids and reduced proportions of monounsaturated and polyunsaturated fat in abdominal as opposed to buttock depots (Malcom et al, 1989; Phinney et al, 1994; Schafer & Overvad, 1990).
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result
1,437
These results are in line with previous reports which confirmed that phorbol esters can enhance the contractile response to EFS [20,52,53], however, these groups did not determine the sensitivity, and concentration-dependent relationship.
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result
1,438
This classical finding (Nachmias and Sansbury, 1974; Legge and Foley, 1980; Wilson, 1980) means that our ability to discriminate contrast is best around a non-zero contrast value, which is typically close to the detection threshold.
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background
1,439
These PKC (1) isoforms can be divided into the following three subgroups based on cofactor requirements: conventional PKCs (a, b, and g), which are dependent on Ca(21) and diacylglycerol (DAG) for activity; novel PKCs (d, e, h, and u), which are not dependent on Ca(21) but are activated by DAG; and atypical PKCs (z, l, and i), which are not dependent on Ca(21) and are not stimulated by DAG (7).
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background
1,440
The most common concepts used are the flipped classroom approach (Mason, Shuman, & Cook, 2013; McLaughlin et al., 2014; Prober & Khan, 2013; Strayer, 2012; Tucker, 2012) and the inverted classroom (Gannod, Burge, & Helmick, 2008; Mason et al., 2013; Strayer, 2012).
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background
1,441
…(Xu, 1997, 2001b); (b) an adaptive algorithm for Gaussian factor analysis and a criterion for determining the dimension of principal subspace (Xu, 1998b); (c) a learned parametric model for Independent Component Analysis (ICA) that works on sources mixed with super-Gaussian and subGaussian…
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method
1,442
Schuler et al. (1999, 2003) used two types of Brassica napus (oilseed rape/canola), a conventional variety and a transgenic variety that expressed Bt toxin Cry1Ac.
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method
1,443
Theoretical studies (17) suggested that slowly growing immunogenic tumors that are sensitive to the immune response would engage regulatory T cell and induce tolerance to themselves, while poorly immunogenic, fast growing tumors would progress in a regulatory T cell independent manner.
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background
1,444
Le taux des patientes perdues de vu varie dans la littérature entre 0 et 12% [7-10,14,17,20,30] et il est le plus souvent inférieur à 4% [8-10,14,20,30].
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background
1,445
To that end, the Internet intervention that successfully increased physical activity in the present study and previous research [12] should be administered in a larger RCT that examines the possible secondary effects of increased physical activity on meaningful outcomes for persons with MS.
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result
1,446
These results are in line with morphological abnormalities in a rabbit model of pneumococcal meningitis [8, 47], in neonatal and adult rat models [7, 51] and in human autopsy cases [20].
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result
1,447
It was reported that ESCs may be short or long term cultivated on synthetic substrates in com mercial chemically defined media (Brafman et al., 2010; Mahlstedt et al., 2010; Higuchi et al., 2011; Lee et al., 2011; Nandivada et al., 2011; Valamehr et al., 2011; Ueda et al., 2012).
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background
1,448
Group living in African herpestids is particularly pronounced in relatively small-bodied species inhabiting open habitats for which predation risk is high (Waser 1981; Rood 1986; Clutton-Brock et al. 1999a; Schneider and Kappeler 2014).
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background
1,449
A hold latch must be inserted at the output of each scan flip-flop in order to implement an enhanced scan flip-flop [3].
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method
1,450
, 2005); however, with longer periods (3 h) of IFN-γ exposure NF-κB binding to DNA was described (Park et al., 2005).
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background
1,451
To assay human p60/GST-procon80 heterodimers, taxolstabilized, tetra-methyl rhodamine-labeled microtubules were immobilized on coverslips by first perfusing flow cells with a mutant kinesin that binds strongly to microtubules but is unable to hydrolyze ATP (McNally and Thomas, 1998).
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method
1,452
reast and the kidney and only few of these 82 cases are reported o be prostate carcinoma [3,6].
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background
1,453
In the study, the PHQ-9 summary score ranged from 0 to 27 (α=0.92) (Mao et al. 2009b).
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background
1,454
In present study, efficacy of CS alone in reduction of histological lesions was moderate which is in agreement with results already reported by Leeb et al. (2000).
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result
1,455
Some of the classes in COLD-Saarb are labeled only for the EXT path and some only for one of the portions A or B (more details in Table I of (Ullah et al 2008)).
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background
1,456
2008), but researchers have since demonstrated that individual differences in baseline metabolic rate can persist over the lifetime of individuals (Nespolo and Franco 2007; Burton et al. 2011; White et al. 2013).
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background
1,457
2 × 8 mm) breath-hold 2D inversion recovery sequence in 14 ICM patients [17].
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background
1,458
congolense [7-11] suggested a complex evolution of PRAC genes in trypanosomes.
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background
1,459
…one manifestation of the BRCA1–TONSL genetic interaction may well operate at sites of UV-induced damage, where both proteins are normally engaged in complex DNA damage responses (Duro et al. 2010; O’Connell et al. 2010; O’Donnell et al. 2010; Piwko et al. 2010; Pathania et al. 2011).
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background
1,460
Diffusion weighted imaging (DWI) revealed a higher apparent diffusion coefficient (ADC) in cortical tubers compared to normal-appearing brain, as well as higher ADC values in epileptogenic tubers in comparison to nonepileptogenic tubers [22].
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background
1,461
Near infrared spectroscopy (NIRS) is a method of studying functional activation through monitoring changes in the haemodynamic properties of the brain (Huppert et al. 2006).
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method
1,462
Although a broad array of research is needed to identify such a threshold dose for reinforcement (e.g., Goodwin et al. 2015; Grebenstein et al. 2015; Hatsukami et al. 2012; Hatsukami et al. 2013a; Hecht 2012), this dose likely is not lower than the threshold dose for discriminating nicotine’s…
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background
1,463
This represents a decrease in the threshold in the UK for the introduction of biologics, which the BSR estimate will increase biologic use from 6 to 8–12 %, a potential doubling of current costs [10, 32].
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background
1,464
Determination of FST analogues for temporally distinct samples has been used in other studies to detect population dynamics (Takami et al. 2004); although our data are limited, they do support the N .
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result
1,465
phylogenetic relationships among taxa from several plant families (Stedje 1998; Doust and Kellog 2002; Goldblatt et al. 2002).
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background
1,466
The maximal aerobic power is a key physiological marker of middle distance running performance and is also considered a good performance predictor in heterogeneous, but not in homogeneous groups (Noakes, 1988).
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background
1,467
Furthermore, the findings herein are in agreement with previous studies reporting a high intra-observer reproducibility of diastolic filling and LV mass measurements [7].
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result
1,468
mentation models such as collision induced dissociation (CID) [133], electron transfer dissociation (ETD) [134], and electro capture dissociation (ECD) [128, 135], which provides
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background
1,469
Overall, the findings are consistent with our previous work (Leonard and Baum, 1998; Leonard et al., 1997a, 1997b) in demonstrating that RHD individuals can use context under conditions of reduced processing demands.
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result
1,470
cresylglucuronide (pCG), p-cresylsulfate (pCS), indole-3acetic acid (IAA), and 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid (CMPF) [9–19], all solutes of pathophysiological relevance.
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background
1,471
Therefore, we generated a yeast strain in which Scp160p expression is under control of a repressible Tet-off operator, which allows rapid depletion of the protein on addition of doxycyclin (11,25).
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method
1,472
[21] Bathymetric maps were generated for each Alvin dive, by merging vehicle navigation and attitude data with traveltimes recorded by the sonar through a series of Matlabk programs [Ballard et al., 2000; Singh et al., 2000; Whitcomb et al., 2000; Ferrini et al., 2004, 2005a].
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method
1,473
Furthermore, we previously showed that the increase of eIF2a phosphorylation induced by Sal 003, a specific inhibitor of its phosphatase, can elevate BACE1 protein levels in 6-month-old 5XFAD mice, which have not yet showed BACE1 upregulation consistent with only marginal changes in eIF2a phosphorylation [3].
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1,474
There are two mechanisms by which rTMS can decrease cortical and corticospinal excitability (Chen et al., 1997; Maeda et al., 2000; Muellbacher et al., 2000; Fierro et al., 2001; Touge et al., 2001; Fitzgerald et al., 2002; Romero et al., 2002; Tsuji and Rothwell, 2002) while increasing rCBF (synaptic activity).
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1,475
Interestingly, recent studies demonstrate that co-administration of L-DOPA with a neuroprotective agent that inhibits excitotoxicity, oxidative stress, and neuroinflammation reduces LID in animal models of PD (Spinnewyn et al., 2011; Aron Badin et al., 2013).
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1,476
Several assessed the appropriate monitoring frames to reliably estimate habitual physical behaviour intensities independently [5, 6, 8].
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1,477
An understanding of the roles of food availability, vegetation cover, grazing intensity and burning on bird nesting success across management types (Little et al. 2013) bring us closer to understanding the overall effect of farming practices on birds in the system as compared to the conservation…
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1,478
Instead they were identified directly from the Encyclopaedia Of DNA Elements Project [65], in which the α-globin cluster is one of the targeted regions [12,66].
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1,479
Recently two novel actin-binding proteins found in mammalian neurons, neurabin I and II, have been shown to bind PP1c (1, 32, 33, 37).
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1,480
Due to its manageable behavior, Kademlia [17] and its variant Kad use iterative routing in their design.
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1,481
Recently, we identified Wnt5a as a novel factor, expressed by feeder cells and Sertoli cells, that supports SSC renewal [7].
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1,482
To our surprise, but as noted in previous research [1], participants rarely if ever engaged in an activity on one device that they were interested in continuing on another, and expressed very little interest in the type of “hand-off” capability we suggested.
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1,483
STAT activation is initially widespread, but must be dampened to produce an optimal number of invasive cells by stage 9 (Starz-Gaiano et al., 2008; Yoon et al., 2011; Monahan and Starz-Gaiano, 2013).
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1,484
Attachment of phage F6 to the type IV pili of Pph is mediated by the viral attachment protein P3 [10,11].
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1,485
In the study by Suwazono et al. (2006), the results were adjusted for age, BMI, smoking and exercise, but not for family history.
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1,486
Previously, it was reported that cofilin defects cause the failure of neural tube closure, and the loss of both cofilin and destrin results in the arrest of epithelial branching with F-actin accumulation in kidney organogenesis [43, 44].
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1,487
For example, Kanamycin sulfate treatment, causing complete loss of OHCs, with preservation of IHCs, results in threshold shifts of 40 dB and more in chinchillas (Woolf et al., 1981).
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1,488
Intratumoral therapy of mice with glioma flank tumors The treatment regimen presented here was modeled after the methods developed by Oldfield and coworkers for Tf-CRM107 (28).
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method
1,489
For example, our findings support the theoretically derived memory-based movement models of Van Moorter et al. (2009), Boyer & Walsh (2010), Spencer (2012) and Nabe-Nielsen et al. (2013), which all predict increased foraging efficiency compared to a forager without memory, and in most cases, an…
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1,490
The basic T-tag suturing method, which had been first described in 2002 [20], was further developed during an Inventorama devoted solely to suturing; improvements to the articulating grasper resulted from the NOTES Toolbox event.
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method
1,491
Furthermore, hypercellular spindle cell areas resembling fibrosarcoma have been described in both SEF and LGFMS (Evans, 1987, 1993; Meis-Kindblom et al., 1995; Antonescu et al., 2001).
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1,492
When simulating alternative initiation at a TISs other than the canonical one, the scanning model of translation initiation was assumed (Kozak 1989).
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method
1,493
We assessed the following aspects of study quality: (1) Study design (RCT, quasi-RCT, quasi-experimental study) (2) Method of allocating participants to trial arms (3) Concealment of allocation sequence from trial staff and from personnel who recruit participants into the trial (for RCTs) (4) Blinding of participants, program staff, and outcome assessors (we did not expect most studies in this field to blind participants and/or facilitators, as preliminary research suggests that these interventions often involve time and personal contact) (5) Baseline differences between trial arms, methods of controlling for differences in analyses (6) Attrition: percentage dropout at each follow-up, differential attrition between trial arms, and differences between dropouts and participants who are retained (7) Method of outcome assessment (e.g., ACASI, bio- markers, self-report) (8) Analytic procedures: Intention to treat, complete case, per-protocol, or treatment-on-the-treated We did not make any exclusions due to study quality, but instead report these aspects of methodological quality in the review.
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1,494
The results support the conclusion that an increased mortality from lung cancer was observed among workers initially employed before 1955 in two soluble/mixed beryllium facilities (Lorain and Reading), but not among beryllium workers at any plant in 1955 or later, or those who worked at facilities that only processed insoluble forms of beryllium materials during any period [15, 16].
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1,495
The Division I players from the current study were older than the Division II players, however, all were within the typical range of collegiate soccer players documented in the literature [3,5,28,29,40,49].
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1,496
A potential NarLbinding site in the arcD promoter (pDH11) was mutated using the crossover PCR technique (Ho et al., 1989).
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method
1,497
Based on the analysis of [9], we know that the number of old contents is the difference of two Poisson distribution and follows the Skellam distribution.
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1,498
(A) Palmitoylation of mSpi would result in membrane association at both termini, whereas mSpiCS cannot be palmitoylated and remains free at its Nterminus. mSpiAG and mSpiCSAG contain mutations that prevent cleavage by Rho (purple asterisks) (Strisovsky et al., 2009).
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1,499
Several studies have shown that hypertension is a good predictor of RAS in patients with CAD or undergoing coronary angiography.(19,20) However, in some studies, hypertension failed to predict the presence of RAS.
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