broad_id
string | depmap_id
string | ccle_name
string | screen_id
string | upper_limit
int64 | lower_limit
float64 | slope
float64 | r2
float64 | auc
float64 | ec50
float64 | ic50
float64 | name
string | moa
string | target
string | disease.area
string | indication
string | smiles
string | phase
string | passed_str_profiling
bool | row_name
string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BRD-K33127281-001-05-6 | ACH-000898 | SNU719_STOMACH | HTS002 | 1 | 2.054122 | -0.210894 | 0.041812 | 1.295149 | 0.000621 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000898 |
BRD-K33127281-001-05-6 | ACH-000040 | U118MG_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 2.081618 | -0.076659 | 0.058737 | 1.474539 | 0.003029 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000040 |
BRD-K33127281-001-05-6 | ACH-000808 | HUH28_BILIARY_TRACT | HTS002 | 1 | 2.234351 | -0.336053 | 0.033871 | 1.487238 | 0.016788 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000808 |
BRD-K33127281-001-05-6 | ACH-000447 | NCIH2228_LUNG | HTS002 | 1 | 0.692336 | 1.673405 | 0.099466 | 0.851662 | 0.092915 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000447 |
BRD-K33127281-001-05-6 | ACH-000715 | SNU1214_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.110276 | 0.668071 | 0.426609 | 0.738275 | 0.721194 | 1.047201 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000715 |
BRD-K33127281-001-05-6 | ACH-000186 | NCIH2444_LUNG | HTS002 | 1 | 1.638769 | -7.541001 | 0.308528 | 1.321035 | 0.080108 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000186 |
BRD-K33127281-001-05-6 | ACH-000542 | HEYA8_OVARY | HTS002 | 1 | 1.190618 | 1.441135 | -0.448807 | 1.075628 | 0.213322 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000542 |
BRD-K33127281-001-05-6 | ACH-000943 | RKO_LARGE_INTESTINE | HTS002 | 1 | 0.175438 | 6.495353 | -0.050713 | 0.951356 | 5.6626 | 6.052144 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000943 |
BRD-K33127281-001-05-6 | ACH-000174 | CAL62_THYROID | HTS002 | 1 | 1.007591 | 0.497635 | -0.221072 | 1.004731 | 0.018318 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000174 |
BRD-K33127281-001-05-6 | ACH-000393 | HLF_LIVER | HTS002 | 1 | 2.659824 | -0.701643 | 0.09976 | 1.192445 | 0.000796 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000393 |
BRD-K33127281-001-05-6 | ACH-000018 | T24_URINARY_TRACT | HTS002 | 1 | 1.648471 | -0.197984 | -0.093992 | 1.199857 | 0.000982 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000018 |
BRD-K33127281-001-05-6 | ACH-000906 | ES2_OVARY | HTS002 | 1 | 0.112028 | 1.323621 | 0.20282 | 0.837297 | 1.821999 | 2.206893 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000906 |
BRD-K33127281-001-05-6 | ACH-000784 | KYSE70_OESOPHAGUS | HTS002 | 1 | 1.650454 | -8.579028 | 0.389025 | 1.324711 | 0.077526 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000784 |
BRD-K33127281-001-05-6 | ACH-000265 | KP4_PANCREAS | HTS002 | 1 | 1.496895 | -0.765355 | 0.244287 | 1.372111 | 1.083778 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000265 |
BRD-K33127281-001-05-6 | ACH-000880 | AGS_STOMACH | HTS002 | 1 | 1.351209 | -3.406822 | 0.637906 | 1.191787 | 0.12217 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000880 |
BRD-K33127281-001-05-6 | ACH-000961 | ISHIKAWAHERAKLIO02ER_ENDOMETRIUM | HTS002 | 1 | 1.057182 | 0.142397 | -0.067665 | 1.039962 | 0.00017 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000961 |
BRD-K33127281-001-05-6 | ACH-000847 | HGC27_STOMACH | HTS002 | 1 | 0.654533 | 1.78521 | 0.100305 | 0.907346 | 0.744791 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000847 |
BRD-K33127281-001-05-6 | ACH-000896 | 647V_URINARY_TRACT | HTS002 | 1 | 1.6393 | -0.503374 | 0.295446 | 1.345101 | 0.123818 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000896 |
BRD-K33127281-001-05-6 | ACH-000685 | L33_PANCREAS | HTS002 | 1 | 1.390255 | -1.167772 | 0.105973 | 1.166432 | 0.038061 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000685 |
BRD-K33127281-001-05-6 | ACH-000376 | SF295_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 2.668117 | -0.211476 | 0.118554 | 1.815201 | 0.06193 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000376 |
BRD-K33127281-001-05-6 | ACH-000749 | DMS273_LUNG | HTS002 | 1 | 1.905941 | -1.035387 | 0.603814 | 1.360403 | 0.028535 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000749 |
BRD-K33127281-001-05-6 | ACH-000572 | G361_SKIN | HTS002 | 1 | 0.953845 | 0.205501 | -0.060253 | 0.969605 | 0.002487 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000572 |
BRD-K33127281-001-05-6 | ACH-000704 | OAW42_OVARY | HTS002 | 1 | 1.751372 | -1.678255 | 0.029216 | 1.146284 | 0.003935 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000704 |
BRD-K33127281-001-05-6 | ACH-000457 | CAL54_KIDNEY | HTS002 | 1 | 0.894994 | 6.762499 | -0.042433 | 0.932435 | 0.019421 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000457 |
BRD-K33127281-001-05-6 | ACH-000601 | MIAPACA2_PANCREAS | HTS002 | 1 | 1.0026 | 0.562105 | -0.123705 | 1.001224 | 0.108065 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000601 |
BRD-K33127281-001-05-6 | ACH-000651 | SW620_LARGE_INTESTINE | HTS002 | 1 | 0.476572 | 7.790178 | 0.276071 | 0.912255 | 1.965681 | 2.911677 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000651 |
BRD-K33127281-001-05-6 | ACH-000361 | SKHEP1_LIVER | HTS002 | 1 | 1.352084 | -0.482764 | 0.117467 | 1.128251 | 0.0154 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000361 |
BRD-K33127281-001-05-6 | ACH-000842 | SW480_LARGE_INTESTINE | HTS002 | 1 | 1.980193 | 0.150797 | 0.007441 | 1.338369 | 6.535407 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000842 |
BRD-K33127281-001-05-6 | ACH-000570 | YKG1_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 1.860133 | 0.011361 | -0.00217 | 1.433183 | 0.021809 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000570 |
BRD-K33127281-001-05-6 | ACH-000396 | J82_URINARY_TRACT | HTS002 | 1 | 0.581293 | 5.349871 | -0.057476 | 0.906432 | 1.143422 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000396 |
BRD-K33127281-001-05-6 | ACH-000777 | KYSE30_OESOPHAGUS | HTS002 | 1 | 0.092257 | 2.302243 | 0.397963 | 0.915107 | 4.273514 | 4.669412 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000777 |
BRD-K33127281-001-05-6 | ACH-000096 | G401_SOFT_TISSUE | HTS002 | 1 | 1.428586 | -7.430515 | 0.236321 | 1.210492 | 0.071683 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000096 |
BRD-K33127281-001-05-6 | ACH-000955 | SNU407_LARGE_INTESTINE | HTS002 | 1 | 2.610142 | -0.672914 | 0.245344 | 1.630271 | 0.024853 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000955 |
BRD-K33127281-001-05-6 | ACH-000940 | AN3CA_ENDOMETRIUM | HTS002 | 1 | 0.760472 | 1.334451 | -0.001645 | 0.937401 | 0.812445 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000940 |
BRD-K33127281-001-05-6 | ACH-001318 | PLCPRF5_LIVER | HTS002 | 1 | 1.817319 | -0.557946 | 0.28949 | 1.40104 | 0.070449 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-001318 |
BRD-K33127281-001-05-6 | ACH-000332 | YAPC_PANCREAS | HTS002 | 1 | 0.759845 | 1.706795 | 0.057779 | 0.887616 | 0.106626 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000332 |
BRD-K33127281-001-05-6 | ACH-000839 | SCABER_URINARY_TRACT | HTS002 | 1 | 0.554382 | 3.509226 | -0.048781 | 0.935077 | 2.437023 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000839 |
BRD-K33127281-001-05-6 | ACH-000082 | G292CLONEA141B1_BONE | HTS002 | 1 | 0.560005 | 4.414495 | 0.400947 | 0.792608 | 0.103163 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000082 |
BRD-K33127281-001-05-6 | ACH-000178 | HS766T_PANCREAS | HTS002 | 1 | 2.537395 | -0.501293 | 0.224875 | 1.388932 | 0.003764 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000178 |
BRD-K33127281-001-05-6 | ACH-000421 | SW837_LARGE_INTESTINE | HTS002 | 1 | 1.174335 | 0.054653 | -0.014844 | 1.096809 | 0.00131 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000421 |
BRD-K33127281-001-05-6 | ACH-000524 | KURAMOCHI_OVARY | HTS002 | 1 | 1.616104 | -0.869503 | 0.166762 | 1.230105 | 0.021892 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000524 |
BRD-K33127281-001-05-6 | ACH-000469 | YH13_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.671116 | 0.883952 | 0.03242 | 0.859042 | 0.159461 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000469 |
BRD-K33127281-001-05-6 | ACH-000153 | NCIH2052_PLEURA | HTS002 | 1 | 1.74399 | -0.100184 | -0.065586 | 1.485592 | 47.80844 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000153 |
BRD-K33127281-001-05-6 | ACH-000805 | COLO679_SKIN | HTS002 | 1 | 0.814095 | 1.413713 | 0.026306 | 0.922573 | 0.176058 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000805 |
BRD-K33127281-001-05-6 | ACH-000429 | A704_KIDNEY | HTS002 | 1 | 1.767467 | -0.2016 | 0.073294 | 1.398687 | 0.11856 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000429 |
BRD-K33127281-001-05-6 | ACH-000108 | KP3_PANCREAS | HTS002 | 1 | 2.063287 | -0.327449 | 0.347718 | 1.236341 | 0.000866 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000108 |
BRD-K33127281-001-05-6 | ACH-000939 | SKUT1_SOFT_TISSUE | HTS002 | 1 | 0.443962 | 3.448604 | 0.339056 | 0.85535 | 0.801057 | 1.511051 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000939 |
BRD-K33127281-001-05-6 | ACH-000323 | 42MGBA_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.134049 | 1.503951 | 0.521963 | 0.879657 | 2.85131 | 3.508906 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000323 |
BRD-K33127281-001-05-6 | ACH-000219 | A375_SKIN | HTS002 | 1 | 0.61312 | 1.259456 | 0.160893 | 0.914571 | 1.239878 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000219 |
BRD-K33127281-001-05-6 | ACH-000903 | FTC133_THYROID | HTS002 | 1 | 1.396589 | -0.929241 | 0.192674 | 1.133416 | 0.015187 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000903 |
BRD-K33127281-001-05-6 | ACH-000054 | HT1080_SOFT_TISSUE | HTS002 | 1 | 2.291167 | -0.209168 | 0.416733 | 1.57101 | 0.023468 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000054 |
BRD-K33127281-001-05-6 | ACH-000302 | SNU1077_ENDOMETRIUM | HTS002 | 1 | 2.266873 | -3.978669 | 0.539416 | 1.589163 | 0.055655 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000302 |
BRD-K33127281-001-05-6 | ACH-000324 | JHOC5_OVARY | HTS002 | 1 | 1.057587 | 0.316653 | -0.094671 | 1.049555 | 0.000107 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000324 |
BRD-K33127281-001-05-6 | ACH-000164 | PANC1_PANCREAS | HTS002 | 1 | 1.665969 | -0.103963 | 0.05506 | 1.290398 | 0.006249 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000164 |
BRD-K33127281-001-05-6 | ACH-000549 | SNU1076_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 1.739747 | -0.304467 | 0.258286 | 1.290648 | 0.014621 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000549 |
BRD-K33127281-001-05-6 | ACH-000650 | IGR37_SKIN | HTS002 | 1 | 0.908347 | 1.035968 | -0.118803 | 0.962334 | 0.187801 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000650 |
BRD-K33127281-001-05-6 | ACH-000217 | JHH6_LIVER | HTS002 | 1 | 2.187197 | -0.119181 | 0.039967 | 1.559304 | 0.028814 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000217 |
BRD-K33127281-001-05-6 | ACH-000463 | NCIH460_LUNG | HTS002 | 1 | 0.709301 | 2.636389 | 0.277923 | 0.92961 | 0.954671 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000463 |
BRD-K33127281-001-05-6 | ACH-000748 | SJSA1_BONE | HTS002 | 1 | 0.837794 | 3.260848 | -0.10819 | 0.917177 | 0.070483 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000748 |
BRD-K33127281-001-05-6 | ACH-000788 | A2058_SKIN | HTS002 | 1 | 0.985698 | 1.521748 | 0.003836 | 0.995847 | 0.60266 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000788 |
BRD-K33127281-001-05-6 | ACH-000545 | VMCUB1_URINARY_TRACT | HTS002 | 1 | 3.020437 | -0.282084 | 0.055629 | 1.792026 | 0.013077 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000545 |
BRD-K33127281-001-05-6 | ACH-000762 | YD38_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 1.359761 | 6.625409 | 0.191745 | 1.282416 | 0.004916 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000762 |
BRD-K33127281-001-05-6 | ACH-000211 | DAOY_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 1.636759 | -0.852171 | 0.096555 | 1.210421 | 0.013996 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000211 |
BRD-K33127281-001-05-6 | ACH-000936 | EFO27_OVARY | HTS002 | 1 | 3.100218 | -0.33372 | -0.020358 | 1.275123 | 0.000109 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000936 |
BRD-K33127281-001-05-6 | ACH-000882 | IGR1_SKIN | HTS002 | 1 | 1.183386 | -0.182379 | 0.035767 | 1.097204 | 0.157695 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000882 |
BRD-K33127281-001-05-6 | ACH-000471 | LI7_LIVER | HTS002 | 1 | 1.329561 | -1.373414 | -0.006732 | 1.010095 | 0.000371 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000471 |
BRD-K33127281-001-05-6 | ACH-000670 | SBC5_LUNG | HTS002 | 1 | 0.86324 | 3.770495 | -0.088803 | 0.954518 | 0.396667 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000670 |
BRD-K33127281-001-05-6 | ACH-000048 | TOV112D_OVARY | HTS002 | 1 | 1.232543 | -2.878802 | 0.016617 | 1.061911 | 0.008082 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000048 |
BRD-K33127281-001-05-6 | ACH-000259 | KELLY_AUTONOMIC_GANGLIA | HTS002 | 1 | 2.163364 | -0.414734 | 0.184063 | 1.340244 | 0.004953 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000259 |
BRD-K33127281-001-05-6 | ACH-000599 | PATU8902_PANCREAS | HTS002 | 1 | 1.284073 | -3.179905 | 0.312485 | 1.171149 | 0.211198 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000599 |
BRD-K33127281-001-05-6 | ACH-000716 | TT2609C02_THYROID | HTS002 | 1 | 0.858479 | 1.891652 | 0.058683 | 0.935819 | 0.122675 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000716 |
BRD-K33127281-001-05-6 | ACH-000347 | QGP1_PANCREAS | HTS002 | 1 | 1.644764 | -0.116594 | 0.01036 | 1.247468 | 0.001212 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000347 |
BRD-K33127281-001-05-6 | ACH-000566 | SW1710_URINARY_TRACT | HTS002 | 1 | 1.450592 | -4.944283 | 0.352076 | 1.224686 | 0.077105 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000566 |
BRD-K33127281-001-05-6 | ACH-001016 | BECKER_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.444533 | 4.397642 | 0.333278 | 0.945551 | 3.876204 | 6.390778 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-001016 |
BRD-K33127281-001-05-6 | ACH-000395 | NCIH520_LUNG | HTS002 | 1 | 1.265592 | 3.322095 | -0.099479 | 1.078497 | 0.568079 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000395 |
BRD-K33127281-001-05-6 | ACH-000407 | SNU685_ENDOMETRIUM | HTS002 | 1 | 2.011982 | -0.186819 | 0.023212 | 1.339061 | 0.00157 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000407 |
BRD-K33127281-001-05-6 | ACH-000191 | BHT101_THYROID | HTS002 | 1 | 1.481716 | -5.050397 | 0.455532 | 1.339952 | 0.575088 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000191 |
BRD-K33127281-001-05-6 | ACH-000941 | HEC1B_ENDOMETRIUM | HTS002 | 1 | 1.52363 | -0.231008 | 0.094581 | 1.262662 | 0.080574 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000941 |
BRD-K33127281-001-05-6 | ACH-000532 | SNU61_LARGE_INTESTINE | HTS002 | 1 | 1.555733 | -0.701073 | 0.283849 | 1.294591 | 0.106763 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000532 |
BRD-K33127281-001-05-6 | ACH-000316 | SNU886_LIVER | HTS002 | 1 | 0.035752 | 0.965356 | 0.390024 | 0.807839 | 1.719615 | 1.85698 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000316 |
BRD-K33127281-001-05-6 | ACH-000677 | SW1573_LUNG | HTS002 | 1 | 1.051948 | 0.177027 | -0.015152 | 1.031358 | 0.006296 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000677 |
BRD-K33127281-001-05-6 | ACH-000375 | G402_SOFT_TISSUE | HTS002 | 1 | 0.41399 | 2.592543 | 0.427537 | 0.81264 | 0.449374 | 0.88606 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000375 |
BRD-K33127281-001-05-6 | ACH-000619 | PECAPJ15_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.373004 | 2.468202 | -0.085585 | 0.906359 | 2.374499 | 4.137246 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000619 |
BRD-K33127281-001-05-6 | ACH-000965 | RL952_ENDOMETRIUM | HTS002 | 1 | 1.40419 | -9.046138 | 0.242545 | 1.230501 | 0.154514 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000965 |
BRD-K33127281-001-05-6 | ACH-000210 | CADOES1_BONE | HTS002 | 1 | 1.309111 | -5.284181 | 0.246634 | 1.228306 | 0.791231 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000210 |
BRD-K33127281-001-05-6 | ACH-000803 | COLO668_LUNG | HTS002 | 1 | 2.395013 | -4.045202 | 0.330863 | 1.562861 | 0.03062 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000803 |
BRD-K33127281-001-05-6 | ACH-000007 | LS513_LARGE_INTESTINE | HTS002 | 1 | 1.635942 | -1.577615 | 0.327298 | 1.405666 | 0.298544 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000007 |
BRD-K33127281-001-05-6 | ACH-000719 | RMGI_OVARY | HTS002 | 1 | 1.245474 | -0.576143 | 0.075089 | 1.105108 | 0.035436 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000719 |
BRD-K33127281-001-05-6 | ACH-000484 | VMRCRCW_KIDNEY | HTS002 | 1 | 2.031632 | -0.239759 | -0.011091 | 1.211228 | 0.000159 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000484 |
BRD-K33127281-001-05-6 | ACH-000433 | CAKI1_KIDNEY | HTS002 | 1 | 1.581469 | -1.950062 | 0.201432 | 1.257976 | 0.045218 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000433 |
BRD-K33127281-001-05-6 | ACH-000603 | BEN_LUNG | HTS002 | 1 | 2.610406 | -0.430315 | 0.490765 | 1.429904 | 0.003613 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000603 |
BRD-K33127281-001-05-6 | ACH-000351 | MKN1_STOMACH | HTS002 | 1 | 1.560227 | 0.186309 | -0.090244 | 1.259977 | 0.178252 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000351 |
BRD-K33127281-001-05-6 | ACH-000627 | LCLC103H_LUNG | HTS002 | 1 | 1.41459 | -1.176982 | 0.411551 | 1.242718 | 0.180161 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000627 |
BRD-K33127281-001-05-6 | ACH-000916 | NCIH1573_LUNG | HTS002 | 1 | 1.68702 | -0.861201 | 0.245949 | 1.246049 | 0.018679 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000916 |
BRD-K33127281-001-05-6 | ACH-000863 | DBTRG05MG_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 1.536743 | -0.162066 | 0.041902 | 1.257857 | 0.046989 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000863 |
BRD-K33127281-001-05-6 | ACH-000732 | PECAPJ41CLONED2_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 1.386568 | -3.274322 | 0.349865 | 1.278513 | 0.663727 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000732 |
BRD-K33127281-001-05-6 | ACH-000015 | NCIH1581_LUNG | HTS002 | 1 | 0.936431 | 2.33679 | -0.333019 | 0.965404 | 0.050865 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000015 |
BRD-K33127281-001-05-6 | ACH-000674 | NUGC4_STOMACH | HTS002 | 1 | 0.609853 | 1.082278 | 0.295932 | 0.862418 | 0.333718 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000674 |
BRD-K33127281-001-05-6 | ACH-000892 | NCIH1563_LUNG | HTS002 | 1 | 0.92848 | 4.84824 | 0.00428 | 0.943459 | 0.004658 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000892 |
BRD-K33127281-001-05-6 | ACH-000909 | JHUEM2_ENDOMETRIUM | HTS002 | 1 | 1.134274 | -1.588039 | 0.056909 | 1.053168 | 0.028428 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000909 |
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