broad_id
string | depmap_id
string | ccle_name
string | screen_id
string | upper_limit
int64 | lower_limit
float64 | slope
float64 | r2
float64 | auc
float64 | ec50
float64 | ic50
float64 | name
string | moa
string | target
string | disease.area
string | indication
string | smiles
string | phase
string | passed_str_profiling
bool | row_name
string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BRD-K33127281-001-05-6 | ACH-000391 | MHHES1_BONE | HTS002 | 1 | 0.201313 | 1.261281 | 0.373237 | 0.796777 | 0.877516 | 1.320254 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000391 |
BRD-K33127281-001-05-6 | ACH-000843 | HARA_LUNG | HTS002 | 1 | 0.489338 | 4.019394 | 0.318567 | 0.750363 | 0.087053 | 0.22675 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000843 |
BRD-K33127281-001-05-6 | ACH-000711 | JIMT1_BREAST | HTS002 | 1 | 1.093535 | 0.922582 | -0.506429 | 1.034364 | 0.293693 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000711 |
BRD-K33127281-001-05-6 | ACH-000232 | U251MG_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.661075 | 4.120166 | -0.063307 | 0.876423 | 0.290642 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000232 |
BRD-K33127281-001-05-6 | ACH-000060 | PANC1005_PANCREAS | HTS002 | 1 | 0.32084 | 3.437349 | 0.415078 | 0.911865 | 2.849495 | 3.840962 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000060 |
BRD-K33127281-001-05-6 | ACH-000322 | HT144_SKIN | HTS002 | 1 | 1.856092 | 0.203381 | -0.126367 | 1.342816 | 0.664571 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000322 |
BRD-K33127281-001-05-6 | ACH-000736 | SNU601_STOMACH | HTS002 | 1 | 0.17027 | 5.763564 | 0.621707 | 0.875448 | 2.330146 | 2.504693 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000736 |
BRD-K33127281-001-05-6 | ACH-000809 | KYSE410_OESOPHAGUS | HTS002 | 1 | 0.518559 | 3.098962 | -0.170989 | 0.915643 | 1.829274 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000809 |
BRD-K33127281-001-05-6 | ACH-000747 | NCIH1703_LUNG | HTS002 | 1 | 0.83203 | 4.057958 | -0.346752 | 0.941286 | 0.336398 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000747 |
BRD-K33127281-001-05-6 | ACH-000364 | U2OS_BONE | HTS002 | 1 | 1.970151 | -9.312362 | 0.419146 | 1.48426 | 0.077489 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000364 |
BRD-K33127281-001-05-6 | ACH-000679 | OE19_OESOPHAGUS | HTS002 | 1 | 1.451832 | -0.625217 | 0.080224 | 1.15253 | 0.013334 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000679 |
BRD-K33127281-001-05-6 | ACH-000985 | LS411N_LARGE_INTESTINE | HTS002 | 1 | 1.750527 | -0.415242 | -0.051907 | 1.298405 | 0.021016 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000985 |
BRD-K33127281-001-05-6 | ACH-001113 | LC1SQSF_LUNG | HTS002 | 1 | 0.725879 | 6.722303 | -0.125741 | 0.907417 | 0.377225 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-001113 |
BRD-K33127281-001-05-6 | ACH-000620 | JHH1_LIVER | HTS002 | 1 | 1.517547 | -0.438897 | 0.117432 | 1.168277 | 0.008477 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000620 |
BRD-K33127281-001-05-6 | ACH-000853 | NCIH661_LUNG | HTS002 | 1 | 1.911872 | -0.110508 | -0.009572 | 1.312163 | 0.000185 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000853 |
BRD-K33127281-001-05-6 | ACH-000102 | GMS10_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 1.448788 | -0.50583 | 0.261556 | 1.148643 | 0.010621 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000102 |
BRD-K33127281-001-05-6 | ACH-000648 | NCIH28_PLEURA | HTS002 | 1 | 1.778629 | -0.483831 | 0.214544 | 1.243712 | 0.008062 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000648 |
BRD-K33127281-001-05-6 | null | null | HTS002 | 1 | 1.29729 | 0.01955 | -0.08267 | 1.159826 | 0.000035 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | false | ACH-000925_FAILED_STR |
BRD-K33127281-001-05-6 | ACH-001239 | WM2664_SKIN | HTS002 | 1 | 3.178089 | -1.415113 | -0.062672 | 1.062972 | 0.000367 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-001239 |
BRD-K33127281-001-05-6 | ACH-001321 | TT_THYROID | HTS002 | 1 | 0.857718 | 4.484416 | -0.025945 | 0.971858 | 1.46701 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-001321 |
BRD-K33127281-001-05-6 | ACH-000279 | EWS502_BONE | HTS002 | 1 | 1.507314 | -2.69022 | 0.216624 | 1.278614 | 0.125924 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000279 |
BRD-K33127281-001-05-6 | ACH-000172 | TM87_SOFT_TISSUE | HTS002 | 1 | 1.636175 | -0.614511 | 0.066468 | 1.151742 | 0.004012 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000172 |
BRD-K33127281-001-05-6 | ACH-000437 | SW1088_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 1.497946 | -4.73596 | 0.278216 | 1.247892 | 0.076496 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000437 |
BRD-K33127281-001-05-6 | ACH-000735 | PECAPJ49_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.914425 | 7.501183 | 0.035684 | 0.971559 | 0.397483 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000735 |
BRD-K33127281-001-05-6 | ACH-000643 | HDQP1_BREAST | HTS002 | 1 | 0.605628 | 0.740509 | 0.14983 | 0.853683 | 0.29664 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000643 |
BRD-K33127281-001-05-6 | ACH-000207 | DETROIT562_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 1.435029 | -0.335226 | 0.136137 | 1.134368 | 0.004377 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000207 |
BRD-K33127281-001-05-6 | ACH-000456 | BCPAP_THYROID | HTS002 | 1 | 0.559313 | -0.636192 | 0.029081 | 0.944978 | 0.000778 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000456 |
BRD-K33127281-001-05-6 | ACH-000260 | SKNAS_AUTONOMIC_GANGLIA | HTS002 | 1 | 2.063729 | -0.543495 | 0.399908 | 1.242243 | 0.002972 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000260 |
BRD-K33127281-001-05-6 | ACH-000019 | MCF7_BREAST | HTS002 | 1 | 1.54739 | -1.318623 | 0.341664 | 1.246842 | 0.048451 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000019 |
BRD-K33127281-001-05-6 | ACH-000582 | COLO741_SKIN | HTS002 | 1 | 1.568008 | -0.440461 | 0.101152 | 1.194192 | 0.010648 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000582 |
BRD-K33127281-001-05-6 | ACH-000990 | HEC108_ENDOMETRIUM | HTS002 | 1 | 1.385095 | -5.747502 | 0.432486 | 1.303564 | 1.281542 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000990 |
BRD-K33127281-001-05-6 | ACH-000592 | TM31_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 2.349789 | -0.244595 | 0.163997 | 1.506354 | 0.007678 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000592 |
BRD-K33127281-001-05-6 | ACH-000368 | SNU1105_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.248153 | 8.249071 | 0.234187 | 0.945404 | 4.94449 | 5.373121 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000368 |
BRD-K33127281-001-05-6 | ACH-000517 | SNU410_PANCREAS | HTS002 | 1 | 1.368645 | -0.012862 | -0.165167 | 1.177394 | 0.000225 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000517 |
BRD-K33127281-001-05-6 | ACH-000374 | HCC1143_BREAST | HTS002 | 1 | 2.125579 | -0.458857 | 0.249451 | 1.402855 | 0.013641 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000374 |
BRD-K33127281-001-05-6 | ACH-000527 | OVISE_OVARY | HTS002 | 1 | 1.244789 | -5.845125 | 0.126306 | 1.191988 | 1.232945 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000527 |
BRD-K33127281-001-05-6 | ACH-000091 | OV56_OVARY | HTS002 | 1 | 1.513963 | -4.660963 | 0.279266 | 1.395337 | 1.064838 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000091 |
BRD-K33127281-001-05-6 | ACH-000759 | MDAMB175VII_BREAST | HTS002 | 1 | 0.49482 | 1.262243 | 0.125455 | 0.743482 | 0.072422 | 2.704917 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000759 |
BRD-K33127281-001-05-6 | ACH-000417 | PANC0813_PANCREAS | HTS002 | 1 | 1.36251 | -1.080855 | 0.267904 | 1.21734 | 0.207786 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000417 |
BRD-K33127281-001-05-6 | ACH-000308 | EFO21_OVARY | HTS002 | 1 | 1.54551 | -0.258709 | 0.139194 | 1.246335 | 0.033491 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000308 |
BRD-K33127281-001-05-6 | ACH-000991 | SNU81_LARGE_INTESTINE | HTS002 | 1 | 1.556889 | -0.499458 | 0.02496 | 1.100461 | 0.001239 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000991 |
BRD-K33127281-001-05-6 | ACH-000948 | 2313287_STOMACH | HTS002 | 1 | 0.413391 | 1.72896 | 0.240304 | 0.885035 | 1.526172 | 4.207151 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000948 |
BRD-K33127281-001-05-6 | ACH-000481 | NCIH2170_LUNG | HTS002 | 1 | 0.611566 | 1.429066 | 0.320844 | 0.873786 | 0.430482 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000481 |
BRD-K33127281-001-05-6 | ACH-000771 | BICR56_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.22635 | 1.053619 | 0.395685 | 0.838067 | 1.476869 | 2.616942 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000771 |
BRD-K33127281-001-05-6 | ACH-000159 | OSRC2_KIDNEY | HTS002 | 1 | 1.359168 | -0.942244 | 0.07999 | 1.089178 | 0.006056 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000159 |
BRD-K33127281-001-05-6 | ACH-000929 | NCIH2110_LUNG | HTS002 | 1 | 0.632985 | 1.411694 | 0.073512 | 0.852468 | 0.202794 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000929 |
BRD-K33127281-001-05-6 | ACH-000118 | HUPT3_PANCREAS | HTS002 | 1 | 1.63413 | -1.193611 | 0.289336 | 1.304548 | 0.064429 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000118 |
BRD-K33127281-001-05-6 | ACH-000352 | HCC1428_BREAST | HTS002 | 1 | 1.469343 | -0.032141 | -0.027229 | 1.22583 | 0.007448 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000352 |
BRD-K33127281-001-05-6 | ACH-000235 | PANC0403_PANCREAS | HTS002 | 1 | 0.995865 | 0.934171 | -0.147735 | 0.997873 | 0.067681 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000235 |
BRD-K33127281-001-05-6 | ACH-000900 | NCIH23_LUNG | HTS002 | 1 | 1.853932 | -0.308071 | 0.080077 | 1.290053 | 0.00622 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000900 |
BRD-K33127281-001-05-6 | ACH-000479 | KNS81_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.879042 | 0.93055 | -0.262927 | 0.945021 | 0.122686 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000479 |
BRD-K33127281-001-05-6 | ACH-000911 | NUGC3_STOMACH | HTS002 | 1 | 1.385292 | -1.77258 | 0.23272 | 1.301336 | 1.223236 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000911 |
BRD-K33127281-001-05-6 | ACH-000401 | COLO800_SKIN | HTS002 | 1 | 0.471824 | 1.407766 | 0.291253 | 0.872381 | 0.984639 | 7.595607 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000401 |
BRD-K33127281-001-05-6 | ACH-000276 | HCC38_BREAST | HTS002 | 1 | 2.112601 | -3.893044 | 0.418843 | 1.648573 | 0.174705 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000276 |
BRD-K33127281-001-05-6 | ACH-000724 | HT1376_URINARY_TRACT | HTS002 | 1 | 2.087298 | -1.354498 | 0.269741 | 1.627765 | 0.165921 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000724 |
BRD-K33127281-001-05-6 | ACH-000092 | NCIH2452_PLEURA | HTS002 | 1 | 1.797527 | -0.134352 | -0.004697 | 1.313124 | 0.002714 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000092 |
BRD-K33127281-001-05-6 | ACH-000890 | SW1271_LUNG | HTS002 | 1 | 1.654871 | -2.676845 | 0.482651 | 1.523323 | 1.426598 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000890 |
BRD-K33127281-001-05-6 | null | null | HTS002 | 1 | 0.451462 | 2.43788 | 0.492169 | 0.87776 | 1.152785 | 3.000724 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | false | ACH-000539_FAILED_STR |
BRD-K33127281-001-05-6 | ACH-000800 | NCIH446_LUNG | HTS002 | 1 | 1.625823 | -1.137203 | 0.061185 | 1.085302 | 0.001837 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000800 |
BRD-K33127281-001-05-6 | ACH-000899 | WM88_SKIN | HTS002 | 1 | 1.601232 | -6.464933 | 0.217108 | 1.233719 | 0.026537 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000899 |
BRD-K33127281-001-05-6 | ACH-000996 | HEC251_ENDOMETRIUM | HTS002 | 1 | 1.915731 | -0.596733 | 0.127973 | 1.398158 | 0.038453 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000996 |
BRD-K33127281-001-05-6 | ACH-000622 | KNS42_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 1.445448 | -1.077864 | 0.238695 | 1.244059 | 0.124999 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000622 |
BRD-K33127281-001-05-6 | ACH-000403 | NCIH747_LARGE_INTESTINE | HTS002 | 1 | 1.65416 | -1.129328 | 0.161982 | 1.399046 | 0.229796 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000403 |
BRD-K33127281-001-05-6 | ACH-000141 | SNU308_BILIARY_TRACT | HTS002 | 1 | 1.348574 | -0.323307 | 0.046495 | 1.13446 | 0.014029 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000141 |
BRD-K33127281-001-05-6 | ACH-000988 | MFE319_ENDOMETRIUM | HTS002 | 1 | 2.270483 | 0.188243 | -0.090954 | 1.647123 | 0.063176 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000988 |
BRD-K33127281-001-05-6 | ACH-000848 | JHH7_LIVER | HTS002 | 1 | 1.307429 | -1.754279 | 0.196229 | 1.220512 | 0.646403 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000848 |
BRD-K33127281-001-05-6 | ACH-000785 | NCIH2126_LUNG | HTS002 | 1 | 1.907804 | -1.53509 | 0.232379 | 1.323497 | 0.01932 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000785 |
BRD-K33127281-001-05-6 | ACH-000544 | OE21_OESOPHAGUS | HTS002 | 1 | 2.958813 | -0.887531 | 0.668254 | 1.359617 | 0.002799 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000544 |
BRD-K33127281-001-05-6 | ACH-000982 | GP2D_LARGE_INTESTINE | HTS002 | 1 | 1.569448 | -13.636522 | 0.306054 | 1.286775 | 0.080902 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000982 |
BRD-K33127281-001-05-6 | ACH-000021 | NCIH1693_LUNG | HTS002 | 1 | 1.816213 | 0.211364 | -0.111203 | 1.304207 | 1.128666 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000021 |
BRD-K33127281-001-05-6 | ACH-000915 | IPC298_SKIN | HTS002 | 1 | 1.375278 | -4.042059 | 0.355321 | 1.278844 | 0.826116 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000915 |
BRD-K33127281-001-05-6 | ACH-000984 | HEC6_ENDOMETRIUM | HTS002 | 1 | 1.673062 | -0.271755 | 0.064445 | 1.265283 | 0.012898 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000984 |
BRD-K33127281-001-05-6 | ACH-000579 | UACC257_SKIN | HTS002 | 1 | 1.822533 | -0.813051 | 0.012808 | 1.040667 | 0.000246 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000579 |
BRD-K33127281-001-05-6 | ACH-001306 | 8305C_THYROID | HTS002 | 1 | 1.752643 | -0.718001 | 0.446951 | 1.400721 | 0.10918 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-001306 |
BRD-K33127281-001-05-6 | ACH-000318 | TE10_OESOPHAGUS | HTS002 | 1 | 1.20149 | 0.058175 | -0.092953 | 1.114111 | 0.000771 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000318 |
BRD-K33127281-001-05-6 | ACH-000840 | HCC366_LUNG | HTS002 | 1 | 1.304365 | -0.603827 | 0.206942 | 1.120663 | 0.025318 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000840 |
BRD-K33127281-001-05-6 | ACH-000503 | BICR16_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 2.017423 | -2.206173 | 0.086234 | 1.089235 | 0.001326 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000503 |
BRD-K33127281-001-05-6 | ACH-000726 | TE14_OESOPHAGUS | HTS002 | 1 | 0.767743 | 3.397085 | 0.121128 | 0.838446 | 0.011709 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000726 |
BRD-K33127281-001-05-6 | ACH-000919 | IM95_STOMACH | HTS002 | 1 | 1.413435 | -1.582353 | 0.278183 | 1.17503 | 0.037102 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000919 |
BRD-K33127281-001-05-6 | ACH-000188 | SCC25_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.510105 | 7.27475 | 0.092623 | 0.925444 | 2.283597 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000188 |
BRD-K33127281-001-05-6 | ACH-000618 | SNU1041_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 1.015729 | 0.429847 | -0.19222 | 1.011579 | 0.003443 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000618 |
BRD-K33127281-001-05-6 | ACH-000292 | NCIH841_LUNG | HTS002 | 1 | 0.616403 | 3.538044 | 0.402151 | 0.936339 | 1.999813 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000292 |
BRD-K33127281-001-05-6 | ACH-000827 | WM793_SKIN | HTS002 | 1 | 0.613708 | 3.288881 | 0.024064 | 0.895564 | 0.725499 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000827 |
BRD-K33127281-001-05-6 | ACH-000411 | 769P_KIDNEY | HTS002 | 1 | 0.491539 | 6.721736 | 0.179318 | 0.953736 | 4.137216 | 7.590419 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000411 |
BRD-K33127281-001-05-6 | ACH-000139 | PANC0327_PANCREAS | HTS002 | 1 | 2.081951 | -5.353837 | 0.406922 | 1.49514 | 0.05179 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000139 |
BRD-K33127281-001-05-6 | ACH-000569 | ISTMES1_PLEURA | HTS002 | 1 | 1.208048 | -0.612025 | 0.033531 | 1.052527 | 0.004773 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000569 |
BRD-K33127281-001-05-6 | ACH-000278 | COV362_OVARY | HTS002 | 1 | 0.662097 | 1.871151 | 0.124693 | 0.940109 | 1.830213 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000278 |
BRD-K33127281-001-05-6 | ACH-000425 | UACC62_SKIN | HTS002 | 1 | 1.664886 | -2.761028 | 0.468924 | 1.435782 | 0.353042 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000425 |
BRD-K33127281-001-05-6 | ACH-000013 | ONCODG1_OVARY | HTS002 | 1 | 1.801475 | -0.029041 | 0.020677 | 1.387063 | 0.007416 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000013 |
BRD-K33127281-001-05-6 | ACH-000231 | KALS1_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 1.816549 | -5.335966 | 0.493633 | 1.193192 | 0.006063 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000231 |
BRD-K33127281-001-05-6 | ACH-000730 | SKMEL5_SKIN | HTS002 | 1 | 1.890903 | -0.116844 | 0.086397 | 1.430199 | 0.042792 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000730 |
BRD-K33127281-001-05-6 | ACH-000500 | SNU46_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 1.500774 | -0.369886 | 0.236373 | 1.293833 | 0.255971 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000500 |
BRD-K33127281-001-05-6 | ACH-000222 | ASPC1_PANCREAS | HTS002 | 1 | 1.400635 | -3.583272 | 0.463201 | 1.294854 | 0.77138 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000222 |
BRD-K33127281-001-05-6 | ACH-000477 | MALME3M_SKIN | HTS002 | 1 | 0.421193 | 1.664803 | -0.03616 | 0.849896 | 0.814785 | 2.47186 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000477 |
BRD-K33127281-001-05-6 | ACH-000223 | HCC1937_BREAST | HTS002 | 1 | 1.62194 | -0.185453 | 0.062561 | 1.249721 | 0.007883 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000223 |
BRD-K33127281-001-05-6 | ACH-000434 | NCIH1915_LUNG | HTS002 | 1 | 1.563897 | -0.553268 | 0.338816 | 1.270874 | 0.062786 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000434 |
BRD-K33127281-001-05-6 | ACH-000744 | NCIH1623_LUNG | HTS002 | 1 | 0.627813 | 0.550496 | 0.137193 | 0.747429 | 0.010119 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000744 |
BRD-K33127281-001-05-6 | ACH-000107 | CAPAN2_PANCREAS | HTS002 | 1 | 1.620631 | -2.930811 | 0.213574 | 1.221981 | 0.019631 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000107 |
BRD-K33127281-001-05-6 | ACH-000516 | CAL78_BONE | HTS002 | 1 | 2.069227 | -0.44637 | -0.019857 | 1.069828 | 0.000052 | null | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000516 |
BRD-K33127281-001-05-6 | ACH-000182 | SNU869_BILIARY_TRACT | HTS002 | 1 | -0.285408 | 15.354936 | 0.040445 | 0.993816 | 9.733965 | 9.451854 | adapalene | retinoid receptor agonist | RARA, RARB, RARG, RXRA, RXRB, RXRG | dermatology | acne vulgaris (AV) | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O | Launched | true | ACH-000182 |
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