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Context: New treatment options are urgently needed for patients with relapsed chronic lymphocytic leukemia (CLL) who fail to respond to currently available therapies or cannot achieve a sustained response. Moreover, targeted agents with less myelotoxicity are necessary to treat patients with multiple comorbidities who would otherwise be unable to tolerate standard regimens. Ibrutinib, a Bruton's tyrosine kinase inhibitor, has shown highly encouraging results in phase I/II trials in patients with treatment-naive, relapsed and refractory CLL even in the presence of high risk disease or poor prognostic markers. In phase I/II trials, ibrutinib 420 mg or 840 mg - given continuously as single agent or at a dose of 420 mg daily in combination with a monoclonal antibody or chemoimmunotherapy - has been associated with high response rates and durable clinical remissions. Phase II and III trials are currently under way for treatment-naive patients, relapsed/refractory patients, and for those patients harboring a 17p deletion.
Question: What is the name of Bruton's tyrosine kinase inhibitor that can be used for treatment of chronic lymphocytic leukemia? | [
"ibrutinib"
] | task469-cc5538ca03fa4ec189bb0dd09edfcb80 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Mortimer Dormer Leggett (April 19, 1821 -- January 6, 1896) was a lawyer, school administrator, professor, and major general of the Union Army during the American Civil War.
Question: Which entity was Mortimer Dormer Leggett a part of? | [
"union army"
] | task469-3373e4b316764f9c9be0427b071e0831 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Estrogens and progesterones are major drivers of breast development but also promote carcinogenesis in this organ. Yet, their respective roles and the mechanisms underlying their action in the human breast are unclear. Receptor activator of nuclear factor B ligand (RANKL) has been identified as a pivotal paracrine mediator of progesterone function in mouse mammary gland development and mammary carcinogenesis. Whether the factor has the same role in humans is of clinical interest because an inhibitor for RANKL, denosumab, is already used for the treatment of bone disease and might benefit breast cancer patients. We show that progesterone receptor (PR) signaling failed to induce RANKL in PR(+) breast cancer cell lines and in dissociated, cultured breast epithelial cells. In clinical specimens from healthy donors and intact breast tissue microstructures, hormone response was maintained and RANKL expression was under progesterone control, which increased RNA stability. RANKL was sufficient to trigger cell proliferation and was required for progesterone-induced proliferation. The findings were validated in vivo where RANKL protein expression in the breast epithelium correlated with serum progesterone levels and the protein was expressed in a subset of luminal cells that express PR. Thus, important hormonal control mechanisms are conserved across species, making RANKL a potential target in breast cancer treatment and prevention.
Question: To the ligand of which receptors does Denosumab (Prolia) bind? | [
"rankl"
] | task469-d6928ba6982a42fdbca4e87f90f832b8 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Maxence Bibie (11 January 1891 - 24 May 1950) was a French politician.
Question: Which language or languages is Maxence Bibie fluent in? | [
"french"
] | task469-d1048101bfa243a0a092d1ca2037cc4b | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Organisms are individual living things. They range from microscopic bacteria to gigantic blue whales (see Figure must be obtained from the environment. Biotic factors are all of the living or once-living aspects of the environment. They include all the organisms that live there as well as the remains of dead organisms. Abiotic factors are all of the aspects of the environment that have never been alive. They include factors such as sunlight, minerals in soil, temperature, and moisture. Ecologists study organisms and environments at several different levels, from the individual to the biosphere. The levels are depicted in Figure 23.2 and described below. For a video introduction to the levels of organization in ecology, click on this link: . MEDIA Click image to the left or use the URL below. URL: An individual is an organism, or single living thing. A population is a group of individuals of the same species that live in the same area. Members of the same population generally interact with each other. A community is made up of all the populations of all the species that live in the same area. Populations in a community also generally interact with each other.
Question: __all the populations of all the species that live in the same area | [
"community"
] | task469-50f9999dcb56413d8f7eb0a4ff56f1fd | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: In follicular lymphoma, a chromosomal translocation commonly occurs between the fourteenth and the eighteenth chromosomes -- t(14;18) -- which places the Bcl-2 gene from chromosome 18 next to the immunoglobulin heavy chain locus on chromosome 14.
Question: Which chromosone can you find Bcl-2? | [
"chromosome 18"
] | task469-298191802b104d868b9cbeccf2223958 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The film opens by cutting back and forth between scenes of a naval ship carrying Admiral Croft (John Woodvine), and a buggy carrying Mr. Shepherd (David Collings) and his daughter Mrs. Clay (Felicity Dean) to Kellynch Hall. Shepherd and Clay are accosted by creditors due to the debts owed by the residence's owner, Sir Walter Elliot (Corin Redgrave), while Croft discusses the end of the Napoleonic Wars with fellow men of the navy. Sir Walter, a vain foppish baronet, is faced with financial ruin unless he retrenches. Though Sir Walter initially opposes the idea, he eventually agrees to temporarily move to Bath while the hall is let; the idea came from Shepherd, family friend Lady Russell (Susan Fleetwood), and Sir Walter's second eldest daughter, the intelligent Anne (Amanda Root). Anne is visibly upset upon learning that the new tenant of Kellynch Hall will be Admiral Croft, who is the brother-in-law of Frederick Wentworth (Ciaran Hinds)a naval captain she was persuaded to reject in marriage nine years previously because of his lack of prospects and connections. Wentworth is now wealthy from serving in the Wars, and has returned to England, presumably to find a wife. Later, Anne expresses to Lady Russell her unhappiness at her family's current financial predicament, and her past decision to reject the captain's proposal of marriage. Anne visits her other sister Mary (Sophie Thompson), a hypochondriac who has married into a local farming family. Anne patiently listens to the various complaints confided in her by each of the Musgrove family; this includes Mary's husband Charles, sisters-in-law Louisa (Emma Roberts) and Henrietta (Victoria Hamilton), and parents-in-law Mr and Mrs Musgrove (Roger Hammond and Judy Cornwell). Captain Wentworth comes to dine with the Musgroves, but Anne avoids going when she volunteers to nurse Mary's injured son. The following morning at breakfast, Anne and Mary are suddenly met briefly by Wentworth, the first time he and Anne have seen each other since she rejected him. Anne later hears that Wentworth thought her so altered that he "would not have known [her] again".[2] Louisa and Henrietta begin to pursue marriage with Wentworth, as the family is unaware of his and Anne's past relationship. Hurt and rejected by Anne's refusal years before, Wentworth appears to court Louisa, much to Anne's chagrin. Later, Wentworth learns Anne also was persuaded by Lady Russell to refuse Charles' offer of marriage, after which Charles instead proposed to Mary. Anne, Wentworth, and the younger Musgroves go to Lyme and visit two of Wentworth's old naval friends, Captain Harville (Robert Glenister) and Captain Benwick (Richard McCabe). While there, Louisa rashly jumps off a staircase in the hopes Wentworth will catch her, sustaining a head injury. Afterwards, Anne goes to Bath to stay with her father and sister. Sir Walter and Elizabeth reveal they have repaired their relationship with a previously disreputable cousin, Mr. Elliot (Samuel West), the heir to the Elliot baronetcy and estate. Anne is introduced to him, and they realise they briefly saw each other in Lyme. Much to Lady Russell's pleasure, Mr. Elliot begins to court Anne, but she remains uncertain of his true character. Meanwhile, Louisa has recovered and become engaged to Captain Benwick. Wentworth arrives in Bath and encounters Anne on several occasions, though their conversations are brief. Anne learns from an old friend, Mrs. Smith (Helen Schlesinger), that Mr. Elliot is bankrupt and only interested in marrying Anne to help ensure his inheritance from her father. Anne also is told that Mr. Elliot wishes to keep the baronet from possibly marrying Mrs. Clay to produce a male heir. Soon after, Wentworth overhears Anne talking with Captain Harville about the constancy of a woman's love, and writes her a letter declaring that he still cares for her. Anne quickly finds him and the two happily walk off down a street, arm in arm. That night at a party, Wentworth announces his intention to marry Anne, much to Mr. Elliot's consternation. The final scene shows Wentworth and
Question: whom, at the age of 19, was anne elliot engaged to? | [
"frederick wentworth"
] | task469-027c515ba37847c5a3e317253008409b | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Paris, 1966...Monsieur Charles Bonnet (Hugh Griffin), the current head of the Bonnet family, custodian of the family's legendary collection of fine art, and a noted collector in his own right, is offering one of his prized paintings at auction. A Cezanne, it sells for a fabulous $515,000, the high point of the auction. When Bonnet's daughter, Nicole (Audrey Hepburn), hears the news on her car radio on her way home from work, she is shocked...and dismayed. The moment she arrives at their elegant old chateau, she runs upstairs calling her father. In his bedroom on the second floor, she opens the door to an antique wardrobe and steps inside, opens a false panel at the back of the wardrobe and climbs a hidden spiral staircase to her father's secret studio in the attic.Bonnet, it turns out, is a forger of fine art...cheerful and charming, but an unrepentant scoundrel. He is putting the finishing touches on his latest project, a flawless rendition of a famous lost Van Gogh. He has even found another painting from the same period, by an unknown artist, and has brushed dirt from the back of that canvas to transfer to his forgery. "I doubt if even Van Gogh himself would have gone to such pains with his work," he boasts. "He didn't have to, Papa," Nicole retorts, "he WAS Van Gogh!" She tells him in a tired voice (for what must surely be the thousandth time) that it's a crime to sell fake masterpieces. He replies that he only sells them to wealthy, private buyers, who get an undeniably fine painting in return.A noise in the driveway sends them both to the window: An armored car, a police van, a black limousine and half a dozen motorcycles have arrived and parked in front of the house. Nicole is terrified that the authorities have at last discovered Bonnet's hobby, but Bonnet explains that he has simply agreed to let the Claver-Lafayette Museum display their exquisite statuette of Venus, purportedly carved by 16th Century sculptor Benvenuto Cellini, in their latest exhibit. Nicole is not reassured: Their Cellini Venus is also a forgery...carved at the end of the 19th century by Bonnet's father, using Bonnet's mother as a model. Unlike paintings, she tells her father, it's an easy matter to detect forged sculptures. Bonnet brushes aside her concerns: since he's merely lending the statue, not selling it, there will be no reason to test its authenticity.He runs downstairs (followed closely by Nicole) to greet Monsieur Grammont (Ferdinand Gravey), the museum director, who is here with his assistants and an armed escort to transport the Venus. Bonnet shows him into the library, where the Venus stands in solitary splendor in its own special niche. Grammont is moved almost to tears by the sight of it...he congratulates Bonnet for keeping this fine piece in France, though he must have had many lucrative offers to buy it. Bonnet smiles modestly, and says, "Well, after all, one is still a Frenchman." The Venus is handed over, secured in a heavily padded case, Grammont thanks Bonnet effusively and leaves. Bonnet is jubilant, but Nicole is still worried. He waves off her concern, saying that her basic trouble is that she's honest...."but I don't tell you that to hurt your feelings," he adds kindly. "I get dizzy spells when we have these conversations, Papa," she complains. He invites her to attend the gala opening at the museum that night...she firmly declines.The Cellini Venus is the star of the exhibit, and Bonnet the most celebrated guest at the gala. Davis Leland (Eli Wallach), a wealthy American industrialist, is also present. He has recently taken up art collecting, and is pursuing it as obssessively as he pursued the acquisition of his millions. He is so taken with the Venus that he determines to find out all about Bonnet and his family...with the goal of somehow acquiring the Venus.The Bonnet chateau
Question: Who shows up at Nichole and Charle's home. | [
"marcel dalio ( nichole's father's cousin)",
"davis"
] | task469-8384ff0a4fea489a8d7640429d9f8a6b | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Leonard (Phoenix) is walking along a bridge over a creek in Brooklyn, when suddenly he jumps into the water in an attempted suicide. He changes his mind and quickly walks home to his parents' apartment. His mother, seeing him dripping wet, tells her husband their son has tried it again and it becomes evident that Leonard has tried to kill himself before. His parents tell him that a potential business partner and his family are invited for dinner that night and ask him to be present. When they arrive, Leonard finds that he had been set up with the other family's daughter, Sandra (Shaw). She inquires about his interest in photography and notices a photo of a girl above his headboard. He explains he had been engaged to the girl for several years, but the relationship was broken off when it turned out both he and his fiancee carried the gene for TaySachs disease, which results in diseased children who generally don't live beyond age 12, so they would be unable to have healthy children. Leonard meets a new neighbor, Michelle (Paltrow), and is immediately attracted to her, choosing to ignore that she has a drug usage problem. He learns that she is dating a married partner in her law firm, Ronald (Koteas). At her request, Leonard agrees to meet Ronald and Michelle for dinner at a restaurant. The couple leave him later that evening, as they have plans to attend the Metropolitan Opera. Leonard returns home upset, but to his surprise, Sandra arrives, sent over by Leonard's parents. She is under the impression that Leonard wanted her to come by, but realizes by his surprised look, that she was set up. She apologizes for the misunderstanding and says that if he isn't interested, a lot of other guys are. Leonard says that he likes her, and they kiss and eventually make love, and with time, his relationship with Sandra deepens. Michelle calls Leonard and says she is sick. He takes her to the hospital, where she has a D&C for a miscarriage. She had not known she was pregnant and is even more upset that Ronald didn't respond to her calls. Leonard takes her home but Ronald arrives. Leonard hides while Ronald apologizes to Michelle for not having come to her aid. Michelle coldly asks Ronald to leave. She then asks Leonard to write something on her forearm with his finger while she falls asleep. Leonard writes "I love you". Two weeks later, Michelle meets Leonard on the roof of their building and tells him that she has broken up with Ronald and is going to San Francisco. Leonard tells her not to leave and professes his love for her. They have sex and plan to leave together the next day for San Francisco. On New Year's Eve, Leonard buys an engagement ring for Michelle. He is then summoned by Sandra's father and is offered a partnership in the family businesses, with the assumption that he is going to marry Sandra. Noticing the jeweler's gift bag Leonard is holding, the father assumes it is for Sandra; Leonard lies that it is. During his parents' New Year's Eve party, Leonard ducks out to the courtyard to meet Michelle. Michelle arrives ten minutes past departure time and tells Leonard that she isn't going to San Francisco, because Ronald, having learned Michelle is leaving him for California, decided to leave his wife and children for her. Distraught, Leonard breaks things off with her for good. Feeling desolate, Leonard heads to the beach, presumably intending to kill himself. When he drops a glove that Sandra had bought for him, he realizes that, in Sandra, he has found someone who loves him and with whom he can build a decent life. He picks up the glove and sees the boxed engagement ring lying on the sand, where he had thrown it from the boardwalk earlier. He returns to the party, where he gives Sandra the ring and embraces her in a prolonged hug.
Question: Who was Michelle dating in the office? | [
"ronald"
] | task469-c1e0532eb69942ccb770060c6150328c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: As of the 2010 United States Census, there were 1,951,269 people, 715,365 households, and 467,916 families residing in the county. The population density was . There were 840,343 housing units at an average density of . The racial makeup of the county was 60.9% white, 10.5% black or African American, 8.7% Asian, 0.7% Pacific islander, 0.7% American Indian, 13.5% from other races, and 5.1% from two or more races. Those of Hispanic or Latino origin made up 29.1% of the population. In terms of ancestry, 11.7% were Germans, 9.1% were Irish people, 7.6% were English people, 6.3% were Italians, and 2.7% were Americans.
Question: Was more of the population English or Italian? | [
"english"
] | task469-bd0d0104934143ebaf63f93f622c6120 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Somewhere in harbourside Sydney, Australia, a family lives within a high-rise apartment building where the mother is preparing a meal and listening to the radio. Her fourteen year old daughter (Jenny Agutter) and six year old son (Luc Roeg) swim in the building's pool overlooking a view of the ocean while their father (John Meillon), deep in troubled thought, watches them from their balcony.One day, the father takes his children, still in their school uniforms, on a picnic into the Outback. He parks the car and reads while his daughter sets up a blanket with their lunch. Her brother plays nearby with his water gun and toy soldiers. Suddenly, and for reasons unclear to his children, the father announces it is time to go and brandishes a gun, firing several shots at them. The boy thinks it all to be a game but his sister understands the danger and shields her brother as they run from their mad father. She watches in horror as her father returns to the car and sets it on fire before seating himself within and putting a bullet into his head. Quickly, and keeping her brother's eyes averted, the girl retrieves their radio, a scarf, and what food she can carry before setting off into the wilderness with her brother.The siblings walk for hours under the hot sun, calmed by irrelevant radio broadcasts, and walking past a host of wild creatures. Come nightfall, they make a crude camp for themselves, much to the boy's delight. In the morning, the girl leads them up a rocky hillside where she hopes to find some bearings. However, she can see nothing but a broad spanse of wilderness. When they finish their lemonade, the girl opens a can of vegetables from which they drink the juice. Recalling an uncle's story of military training, the girl suggests they eat salt to retain water and surmises to her brother that they may spend some time in the desert. She remains stoic, but wary, while her brother is blissfully unaware of their situation, remaining entertained by the radio and his toys. Eventually, after becoming filthy and tired, they come upon a lone tree standing over a pool of water where parakeets flock and feast on fallen fruit. The boy puts on in his mouth and proclaims that it 'tastes lovely'. They wash in the water and the girl scolds her brother to take care of his clothes so they will last. When he asks if they are lost, the girl replies that they are not, trying to remain chipper. They sleep to the sounds of the radio as night animals stir around them.In the morning, the girl wakes to find that their water hole has dried up and the fruit has either been eaten or spoiled. The girl decides to remain where they are, hoping that the water will return. As they nap in the hot sun, the boy spots an aborigine youth (David Gulpilil) pursuing an animal for food. They make contact and the children attempt to communicate with the aborigine boy. However, he does not understand their language and merely stares at them with curiosity. The girl repeats their need for water but the word is incomprehensible to the aborigine. When her brother mimics drinking, the aborigine understands and shows them how to dig for water using a hollow tube to drink through. Assuming that he will lead them to civilization, the siblings accompany the aborigine, unaware that he is on a 'walkabout', a coming-of-age journey that every male aborigine youth must take alone in order to be initiated as an adult in his tribe.As they travel the Outback, the aborigine kills and harvests food for them, giving them all plenty to eat and drink. The move from the desert to greener pastures and forests where wildlife becomes plentiful. When the boy becomes sunburnt from going shirtless, the aborigine rubs pig fat on his back to alleviate the burn. While communication between them remains limited, the trio share food and play together, though cultural differences are evident; the boy attempts to share his toy soldiers with the aborigine, but he finds no use for them and tosses
Question: What country does the movie take place? | [
"sydney, australia"
] | task469-f3cecdec07a542bab02ed161c3bfd5ae | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Restless legs syndrome (RLS) has gradually been recognized as a cause for insomnia in adults, but there have been few reports about children with RLS in Japan. Here we described seven pediatric RLS patients. All of the parents of our patients had difficult times to make their children sleep due to irritability, restlessness, and demanding bedtime routines. All patients had asked their parents to rub their feet in bed, and it took more than half an hour to soothe them until they fell asleep. Their mothers had been exhausted from this night-time routine. However, they did not consider the routine abnormal, as it had been their habitual behavior since infancy. Some parents were too distressed or embarrassed to describe the symptoms of their child properly. Five patients had clear family history and none had obvious periodic leg movements during sleep. All patients showed low levels of ferritin and iron supplementation was effective in five cases. In the severest two cases, pramipexole, but not iron, was dramatically effective. Both patients started to show RLS symptoms in the early days of infancy, which may suggest more severe hereditary dopaminergic dysfunction. RLS does occur in childhood and pediatricians should bear it in mind as one of the differential diagnoses when seeing children who are irritated and/or having difficulty in initiating their sleep.
Question: Which deficiency is the cause of restless leg syndrome? | [
"iron"
] | task469-ec0a480d8ae64dfb8ee93012e2442c3b | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: While I was waiting to enter university,I saw advertised in a local newspaper a teaching post at a school in a suburb of London about ten miles from where I lived. Being very short of money, I applied. Three days later, a letter arrived, asking me to go to Croydon for an interview. It proved a tiring journey: a train to Croydon station; a ten-minute bus ride and then a walk of at least fifteen minutes. It was clearly the headmaster himself that opened the door. He was short and fat, with a grey-color1ed moustache,a deeply lined face and hardly any hair. He looked at me with surprised disapproval. Then he said. "You'd better come inside." Leading me into his study, he started to ask me a number of questions: what subjects I had taken in my General School Certificate;how old I was; what games I played; whether I thought games were an important part of a boy's education, etc. I said something about not attaching too much importance to them. We obviously had very little in common. The teaching arrangement filled me with fear. I was to divide the class of twenty-four boys, aged from seven to thirteen, into three groups and teach them all subjects--including art, football, cricket and so on--in turn at three different levels. Actually, I was depressed at the thought of teaching algebra and geometry--two subjects in which I had been rather weak at school. I said shyly, "What would my salary be?" "Twelve pounds a week plus lunch." Before I could speak, he got to his feet. "Now," he said, "you'd better meet my wife. She's the one who really runs this school." This was the last thing I could hear. I was young. How could my dignity allow me to work under an old woman?
Question: Which subjects was the writer poor at? | [
"algebra and geometry,"
] | task469-fee5775b35894dbfbcecacf1c2ccd13d | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: at the Georgia Dome, Atlanta, Georgia Trying to end a three-game skid, the Falcons returned home for an NFC South rematch with the New Orleans Saints. From the get-go, the Falcons trailed as in the first quarter, QB Drew Brees completed a 76-yard TD pass to WR Devery Henderson, while RB Deuce McAllister got a 1-yard TD run. Atlanta would respond with kicker Morten Andersen kicking a 22-yard field goal. In the second quarter, Andersen gave the Falcons a 30-yard field goal, yet New Orleans continued dominating with Brees completing an incredible 48-yard TD pass to WR Terrance Copper on the very last offensive play of the half. In the third quarter, RB Warrick Dunn gave Atlanta some room to operate, as he a 1-yard TD run for the only score of the half. However, in the fourth quarter, the Saints wrapped up the game with kicker John Carney getting a 25-yard field goal, while McAllister got a 9-yard TD run. After the game, as QB Michael Vick was leaving the field, he flicked off an insulting fan with both hands. He was fined $10,000 from the NFL and had to donate another $10,000 to charity. With their fourth-straight loss, the Falcons fell to 5-6.
Question: Who scored first | [
"saints"
] | task469-5fee1ca855bf466382ff44592f0be1c0 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: In 2009 Fukushimas industries directly employed 18,678 workers and shipped 671 billion worth of goods. This was led by information-related industries with 50.5% of total output. Other industries in Fukushima include those dealing with food at 7.6% of total output, metals at 7.5%, chemistry at 5.3%, ceramics at 4.9%, electricity at 4.5%, printed goods at 2.8%, steel at 2.5%, plastics at 2.5%, and electronics at 2.2%. Other various industries make up the final 9.8%.
Question: What industries made up the largest percentage? | [
"information-related industries"
] | task469-b1064b41dd504156ad6d0172f79753fd | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: During active transport, molecules move from an area of low concentration to an area of high concentration. This is the opposite of diffusion, and these molecules are said to flow against their concentration gradient. Active transport is called "active" because this type of transport requires energy to move molecules. ATP is the most common source of energy for active transport. As molecules are moving against their concentration gradients, active transport cannot occur without assistance. A carrier protein is always required in this process. Like facilitated diffusion, a protein in the membrane carries the molecules across the membrane, except this protein moves the molecules from a low concentration to a high concentration. These proteins are often called "pumps" because they use energy to pump the molecules across the membrane. There are many cells in your body that use pumps to move molecules. For example, your nerve cells (neurons) would not send messages to your brain unless you had protein pumps moving molecules by active transport. The sodium-potassium pump ( Figure 1.1) is an example of an active transport pump. The sodium-potassium pump uses ATP to move three sodium (Na+ ) ions and two potassium (K+ ) ions to where they are already highly concentrated. Sodium ions move out of the cell, and potassium ions move into the cell. How do these ions then return to their original positions? As the ions now can flow down their concentration gradients, facilitated diffusion returns the ions to their original positions either inside or outside the cell.
Question: which statement is true concerning active transport? | [
"during active transport, molecules move from an area of low concentration to"
] | task469-1c6833f973a843b081dd44a5d9c67cad | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: As of the census of 2000, there were 120,546 people, 41,668 households, and 32,292 families residing in the county. The population density was 262 people per square mile (101/km). There were 43,903 housing units at an average density of 95 per square mile (37/km). The racial makeup of the county was 68.51% Race (United States Census), 26.06% Race (United States Census) or Race (United States Census), 0.75% Race (United States Census), 1.82% Race (United States Census), 0.06% Race (United States Census), 0.72% from Race (United States Census), and 2.08% from two or more races. 2.26% of the population were Race (United States Census) or Race (United States Census) of any race. 11.6% were of german people, 10.8% irish people, 10.2% english people, 9.3% American and 5.3% italian people ancestry.
Question: Which group from the census is larger: irish or english? | [
"irish"
] | task469-6c1c67f40ed146b78a8c20466516d73c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Seahawks began their 2008 campaign on the road against the Buffalo Bills. In the first quarter, Seattle trailed early as Bills RB Marshawn Lynch got a 21-yard TD run. In the second quarter, the Seahawks continued to struggle as WR/PR Roscoe Parrish returned a punt 63 yards for a touchdown. Seattle responded with QB Matt Hasselbeck completing a 20-yard TD pass to WR Nate Burleson. Buffalo closed out the half with kicker Rian Lindell getting a 35-yard and a 38-yard field goal. In the third quarter, the Seahawks replied with kicker Olindo Mare nailing a 45-yard field goal. However, the Bills pulled a trick play on Seattle. Appearing to go for a 32-yard field goal, Buffalo's holder (punter Brian Moorman) instead threw a 19-yard TD pass to DE Ryan Denney. The Bills pulled away with QB Trent Edwards completing a 30-yard TD pass to TE Robert Royal.
Question: Which player scored the first touchdown of the game? | [
"marshawn lynch"
] | task469-756e9aae9a1d4a8db91de3bd9950016b | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Godfather Part II presents two parallel storylines. One involves Mafia chief Michael Corleone in 1958/1959 after the events of the first movie; the other is a series of flashbacks following his father, Vito Corleone from 1917 to 1925, from his youth in Sicily (1901) to the founding of the Corleone family in New York.The film begins in 1901, in the town of Corleone, Sicily, at the funeral of young Vito's father, Antonio Andolini, who has been murdered for an insult to the local Mafia lord, Don Ciccio. During the procession, Vito's older brother is murdered because he swore revenge on the Don. Vito's mother goes to Ciccio to beg for mercy, but he refuses, knowing that nine-year-old Vito will seek revenge later in life. The mother takes Ciccio hostage at knifepoint, allowing her son to escape, and Ciccio's men kill her. They search the town for the boy, but he is aided in his escape by the townspeople. Vito finds his way by ship to New York, and at Ellis Island an immigration agent chooses Vito's hometown of Corleone as his surname, and he is registered as "Vito Corleone".In 1958 in a scene similar to the opening of the first film, Michael Corleone (Al Pacino), Godfather of the Corleone family, deals with various business and family problems during an elaborate party at his Lake Tahoe, Nevada compound to celebrate his son's First Communion. In his office, Michael meets with corrupt Nevada Senator Pat Geary (G. D. Spradlin) to discuss the price of the gaming licenses for the hotel/casinos the Family is buying. Geary, who has obvious contempt for Michael and other Italian businessmen who are moving into his state to take advantage of gambling opportunities, promises to make Michael's acquisition of his gaming license a difficult process. Michael ends his conversation with Geary when he refuses to pay the outrageous fee Geary demands, telling the senator he'll get nothing.Michael also deals with his self-indulgent younger sister Connie (Talia Shire), who, although recently divorced from her second husband, is planning to marry a man named Merl Johnson (Troy Donahue) with no obvious means of support and of whom Michael disapproves. He also talks with Johnny Ola (Dominic Chianese), the right hand man of Jewish gangster Hyman Roth (Lee Strasberg), who is supporting Michael's move into the gambling industry. Belatedly, Michael deals with Frank "Five Angels" Pentangeli (Michael V. Gazzo), a business associate who took over Corleone caporegime Peter Clemenza's territory in New York City after his death, and now has problems with the Rosato Brothers, who are backed by Roth. Pentangeli leaves abruptly, after telling Michael "your father did business with Hyman Roth, your father respected Hyman Roth, but your father never trusted Hyman Roth."Later that night, Michael barely escapes an assassination attempt when his wife Kay (Diane Keaton) notices the bedroom window drapes are inexplicably open, which allows two unseen hitmen to spray the bedroom with bullets. The two hitman are found dead having been killed by a "mole" within the compound. Afterwards, Michael tells his lawyer and associate Tom Hagen (Robert Duvall) that the hit was made with the help of someone close, and that he must leave, entrusting all his power to Hagen to protect his family.Flashback: In 1917 New York City, the adult Vito Corleone (Robert De Niro) works in a grocery store in the Lower East side with his friend Genco Abbandando. The neighborhood is controlled by a member of the "The Black Hand," Don Fanucci (Gastone Moschin), who extorts protection payments from local businesses. One night, Vito's neighbor Clemenza (Bruno Kirby) asks him to hide a stash of guns for him, and later, to repay the favor, takes him to a fancy apartment where they commit their first felony together, stealing an elegant rug.The film flash-forwards to Michael's time. Michael meets with poushal Hyman Roth in Miami, Florida who tells Michael that he believes Frank Pentangeli was responsible for the assassination attempt, and that Pentangeli will pay for it
Question: Fredo seems to begin by who at the funeral? | [
"michael",
"al neri"
] | task469-4657258394884de2a3c0c8ab09743e3e | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Eukaryotic cells have many specific functions, so it can be said that a cell is like a factory. A factory has many machines and people, and each has a specific role. Just like a factory, the cell is made up of many different parts. Each part has a special role. The different parts of the cell are called organelles, which means "small organs." All organelles are found in eukaryotic cells. Prokaryotic cells are "simpler" than eukaryotic cells. Though prokaryotic cells still have many functions, they are not as specialized as eukaryotic cells, lacking membrane-bound organelles. Thus, most organelles are not found in prokaryotic cells. Below are the main organelles found in eukaryotic cells ( Figure 1.1): 1. The nucleus of a cell is like a safe containing the factorys trade secrets. The nucleus contains the genetic material (DNA), the information needed to build thousands of proteins. 2. The mitochondria are the powerhouses of the cell. Mitochondria are the organelles where cellular energy is produced, providing the energy needed to power chemical reactions. This process, known as cellular respiration, produces energy is in the form of ATP (adenosine triphosphate). Cells that use a lot of energy may have thousands of mitochondria. 3. Vesicles are small membrane bound sacs that transport materials around the cell and to the cell membrane. 4. The vacuoles are like storage centers. Plant cells have larger vacuoles than animal cells. Plants store water and nutrients in their large central vacuoles. 5. Lysosomes are like the recycling trucks that carry waste away from the factory. Lysosomes have digestive enzymes that break down old molecules into parts that can be recycled. 6. In both eukaryotes and prokaryotes, ribosomes are the non-membrane bound organelles where proteins are made. Ribosomes are like the machines in the factory that produce the factorys main product. Proteins are the main product of the cell. 7. Some ribosomes can be found on folded membranes called the endoplasmic reticulum (ER), others float freely in the cytoplasm. If the ER is covered with ribosomes, it looks bumpy like sandpaper, and is called the rough endoplasmic reticulum. If the ER does not contain ribosomes, it is smooth and called the smooth endoplasmic reticulum. Many proteins are made on the ribosomes on the rough ER. These proteins immedi- ately enter the ER, where they are modified, packaged into vesicles and sent to the Golgi apparatus. Lipids are made in the smooth ER. 8. The Golgi apparatus works like a mail room. The Golgi apparatus receives proteins from the rough ER and puts "shipping addresses" on them. The Golgi then packages the proteins into vesicles and sends them to the right place in the cell or to the cell membrane. Some of these proteins are secreted from the cell (they exit the cell); others are placed into the cell membrane. Also, the cytoskeleton gives the cell its shape, and the flagella helps the cell to move. Prokaryotic cells may also have flagella.
Question: which organelle acts like the mail room of the cell? | [
"the golgi apparatus"
] | task469-316f3234e3574e6d9e6479c366eb9f29 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Have you ever been to the ocean or eaten seafood? If you have, then youve probably encountered members of Phylum Mollusca. In addition to snails, mollusks include squids, slugs, scallops, and clams. You can see a clam in Figure 12.15. There are more than 100,000 known species of mollusks. Some mollusks are nearly microscopic. The largest mollusk, the colossal squid, may be as long as a school bus and weigh over half a ton! Watch this short video to see an amazing diversity of mollusks: . MEDIA Click image to the left or use the URL below. URL: Mollusks have a true coelom and complete digestive system. They also have circulatory and excretory systems. They have a heart that pumps blood, and organs that filter out wastes from the blood. You can see some other traits of mollusks in the garden snail in Figure 12.16. Like the snail, many other mollusks have a hard outer shell. It is secreted by special tissue called mantle on the outer surface of the body. The shell covers the top of the body and encloses the internal organs. Most mollusks have a distinct head region. The head may have tentacles for sensing the environment and grasping food. Mollusks generally have a muscular foot, which may be used for walking or other purposes. A unique feature of mollusks is the radula. This is a feeding organ with teeth made of chitin. It is located in front of the mouth in the head region. It can be used to scrape algae off rocks or drill holes in the shells of prey. You can see the radula of the sea slug in Figure 12.17. Mollusks reproduce sexually. Most species have separate male and female sexes. Fertilization may be internal or external, depending on the species. Fertilized eggs develop into larvae. There may be one or more larval stages. Each one is different from the adult stage. Mollusks live in most terrestrial, freshwater, and marine habitats. However, the majority of species live in the ocean. They can be found in both shallow and deep water and from tropical to polar latitudes. They have a variety of ways of getting food. Some are free-living heterotrophs. Others are internal parasites. Mollusks are also eaten by many other organisms, including humans. Annelids are segmented worms in Phylum Annelida. There are about 15,000 species of annelids. They range in length from less than a millimeter to more than 3 meters. To learn more about the amazing diversity and adaptations of annelids, watch this excellent video: [Link] MEDIA Click image to the left or use the URL below. URL: Annelids are divided into many repeating segments. The earthworm in Figure 12.18 is an annelid. You can clearly see its many segments. Segmentation of annelids is highly adaptive. Each segment has its own nerve and muscle tissues. This allows the animal to move very efficiently. Some segments can also be specialized to carry out particular functions. They may have special structures on them. For example, they might have tentacles for sensing or feeding, paddles for swimming, or suckers for clinging to surfaces. Annelids have a large coelom. They also have several organ systems. These include a: circulatory system; excretory system; complete digestive system; and nervous system, with a brain and sensory organs. Most annelids can reproduce both asexually and sexually. Asexual reproduction may occur by budding or fission. Sexual reproduction varies by species. Some species go through a larval stage before developing into adults. Other species grow to adult size without going through a larval stage. Annelids live in a diversity of freshwater, salt-water, and terrestrial habitats. They vary in what they eat and how they get their food. Some annelids, such as earthworms, eat soil and extract organic material from it. Annelids called leeches are either predators or parasites. Some leeches capture and eat other invertebrates. Others feed off the blood of vertebrate hosts. Annelids called polychaete worms live on the ocean floor. They may be filter feeders, predators, or scavengers. The amazing feather duster worm in Figure 12.19 is a polychaete that has a fan-like crown of
Question: What are leeches? | [
"segmented worms"
] | task469-43c843822b954c66bf4931aa7a72d829 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: This section's plot summary may be too long or excessively detailed. Please help improve it by removing unnecessary details and making it more concise. (July 2015) (Learn how and when to remove this template message) The film's premise is that there is another way to heaven than adherence to the practices of the Roman Catholic Church. A secular Sin Eater can remove all taint of sin, no matter how foul, from the soul just before death. The purified soul can then ascend into heaven. The Roman Catholic Church, according to the film, considers this heresy. Heath Ledger plays an unhappy and disillusioned priest, Alex Bernier, a member of a fictitious religious order The Carolingians which specializes in fighting demons and other hell spawn. Father Dominic, the head of the Carolingians, has died in Rome under suspicious circumstances and Alex leaves the United States to investigate. In Rome, Alex visits the morgue and sees strange markings on Dominic's corpse. After some investigation, he comes across a book that explains the markings as being the sign of a Sin Eater's work. He heads to the Vatican, where an official tells him that Sin Eaters don't exist and that Dominic may not be buried on sacred ground because he had been excommunicated for his beliefs. Alex, moving ever farther from his vocation, defies his superiors and secretly reads a holy service over the body and buries Dominic in the Carolingian cemetery (the service takes place off screen but is referred to later). Thomas Garrett, another Carolingian (there seem to have only been a total of three including Dominic), arrives in Rome to help investigate Dominic's death. Early in the film we meet Mara Williams, an artist Alex once exorcised, who has escaped from a mental hospital and come to Alex at his church in the USA because she has a feeling that something terrible is going to happen to him. The police come looking for her, but Alex lies and denies that he's seen her and through this exchange we learn that Mara was in the hospital because she had tried to kill Alex during the exorcism. Mara goes to Rome with Alex after promising that she won't try to kill him again. Cardinal Driscoll (Peter Weller), who is introduced at the beginning of the film and who is tipped to be the next Pope, arrives in Rome from the USA and gives Alex a special dagger. According to a fragment of parchment Alex and Thomas find among Dominic's books, the dagger is to be plunged into the Sin Eater while reciting a text in Aramaic. Alex and Thomas take these instructions to mean that the dagger and incantation will kill the Sin Eater and they begin hunting for the Sin Eater and the remainder of the parchment instructions. Thomas leads Alex to a nightclub where they are taken to the underground base of operations of a masked man called Chirac, the 'Black Pope.' The Black Pope owes a favor to Thomas and Alex asks where to find the Sin Eater. The Black Pope then hangs three people and tells Alex to ask his question of the dying men who can see what the living cannot. One of the dying tells Alex a riddle that leads to a rendezvous with the Sin Eater. On the way out of the Black Pope's headquarters, demons attack and injure Thomas, but Alex saves him and gets him to a hospital. Alex leaves Thomas in the hospital and meets the Sin Eater, William Eden, at St. Peter's Cathedral who explains that he has been a Sin Eater for centuries, taking over for an earlier Sin Eater (a Carolingian priest) who ate the sins of Eden's brother. Eden is very charismatic and talks with Alex about the priest's desires, and Alex admits he wants Mara. He then goes and presumably tells Mara this, and they make love. Afterward, Alex leaves Mara asleep and goes to Eden, who tells Alex that he is tired and ready to die and asks Alex to take his place. Alex has the dagger with him, but is curious and so doesn't use it to kill Eden. Instead, he assists Eden with a sin eating
Question: Who wanted Alex to take his place and become the next sin-eater? | [
"william eden"
] | task469-9d49ba7c44fe42aeb6e5de6c39972e43 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Water is a simple chemical compound. Each molecule of water contains two hydrogen atoms (H2 ) and one oxygen atom (O). Thats why the chemical formula for water is H2 O. If water is so simple, why is it special? Water is one of the few substances that exists on Earth in all three states of matter. Water occurs as a gas, a liquid and a solid. You drink liquid water and use it to shower. You breathe gaseous water vapor in the air. You may go ice skating on a pond covered with solid water ice in the winter. Earth is often called the water planet. Figure 13.1 shows why. If astronauts see Earth from space, this is how it looks. Notice how blue the planet appears. Thats because oceans cover much of Earths surface. Water is also found in the clouds that rise above the planet. Most of Earths water is salt water in the oceans. As Figure 13.2 shows, only 3 percent of Earths water is fresh. Freshwater is water that contains little or no dissolved salt. Most freshwater is frozen in ice caps and glaciers. Glaciers cover the peaks of some tall mountains. For example, the Cascades Mountains in North America and the Alps Mountains in Europe are capped with ice. Ice caps cover vast areas of Antarctica and Greenland. Chunks of ice frequently break off ice caps. They form icebergs that float in the oceans. Did you ever wonder where the water in your glass came from or where its been? The next time you take a drink of water, think about this. Each water molecule has probably been around for billions of years. Thats because Earths water is constantly recycled. Water is recycled through the water cycle. The water cycle is the movement of water through the oceans, atmo- sphere, land, and living things. The water cycle is powered by energy from the Sun. Figure 13.3 diagrams the water cycle. Water keeps changing state as it goes through the water cycle. This means that it can be a solid, liquid, or gas. How does water change state? How does it keep moving through the cycle? As Figure 13.3 shows, several processes are involved. Evaporation changes liquid water to water vapor. Energy from the Sun causes water to evaporate. Most evaporation is from the oceans because they cover so much area. The water vapor rises into the atmosphere. Transpiration is like evaporation because it changes liquid water to water vapor. In transpiration, plants release water vapor through their leaves. This water vapor rises into the atmosphere. Condensation changes water vapor to liquid water. As air rises higher into the atmosphere, it cools. Cool air can hold less water vapor than warm air. So some of the water vapor condenses into water droplets. Water droplets may form clouds. Precipitation is water that falls from clouds to Earths surface. Water droplets in clouds fall to Earth when they become too large to stay aloft. The water falls as rain if the air is warm. If the air is cold, the water may freeze and fall as snow, sleet, or hail. Most precipitation falls into the oceans. Some falls on land. Runoff is precipitation that flows over the surface of the land. This water may travel to a river, lake, or ocean. Runoff may pick up fertilizer and other pollutants and deliver them to the water body where it ends up. In this way, runoff may pollute bodies of water. Infiltration is the process by which water soaks into the ground. Some of the water may seep deep under- ground. Some may stay in the soil, where plants can absorb it with their roots. In all these ways, water keeps cycling. The water cycle repeats over and over again. Who knows? Maybe a water molecule that you drink today once quenched the thirst of a dinosaur.
Question: process in which plants release water vapor through their leaves | [
"transpiration"
] | task469-8059413644b448d090dd22eb77adf37e | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Electromagnetic radiation is energy that travels in waves across space as well as through matter. Most of the electromagnetic radiation on Earth comes from the sun. Like other waves, electromagnetic waves are characterized by certain wavelengths and wave frequencies. Wavelength is the distance between two corresponding points on adjacent waves. Wave frequency is the number of waves that pass a fixed point in a given amount of time. Electromagnetic waves with shorter wavelengths have higher frequencies and more energy. Visible light and infrared light are just a small part of the full range of electromagnetic radiation, which is called the electromagnetic spectrum. You can see the waves of the electromagnetic spectrum in the Figure 1.1. At the top of the diagram, the wavelengths of the waves are given. Also included are objects that are about the same size as the corresponding wavelengths. The frequencies and energy levels of the waves are shown at the bottom of the diagram. Some sources of the waves are also given. On the left side of the electromagnetic spectrum diagram are radio waves and microwaves. Radio waves have the longest wavelengths and lowest frequencies of all electromagnetic waves. They also have the least amount of energy. On the right side of the diagram are X rays and gamma rays. They have the shortest wavelengths and highest frequencies of all electromagnetic waves. They also have the most energy. Between these two extremes are waves that are commonly called light. Light includes infrared light, visible light, and ultraviolet light. The wavelengths, frequencies, and energy levels of light fall in between those of radio waves on the left and X rays and gamma rays on the right. Q: Which type of light has the longest wavelengths? A: Infrared light has the longest wavelengths. Q: What sources of infrared light are shown in the diagram? A: The sources in the diagram are people and light bulbs, but all living things and most other objects give off infrared light.
Question: electromagnetic waves with the longest wavelengths are | [
"radio waves."
] | task469-9c211a66ad4e45cd9a95ae4bfc626046 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: In the Atlantic, the West India Company concentrated on wresting from Portugal its grip on the sugar and slave trade, and on opportunistic attacks on the Spanish treasure fleets on their homeward bound voyage. Bahia on the north east coast of Brazil was captured in 1624 but only held for a year before it was recaptured by a joint Spanish-Portuguese expedition. In 1628, Piet Heyn captured the entire Spanish treasure fleet, and made off with a vast fortune in precious metals and goods that enabled the Company two years later to pay its shareholders a cash dividend of 70%, though the Company was to have relatively few other successes against the Spanish. In 1630, the Dutch occupied the Portuguese sugar-settlement of Pernambuco and over the next few years pushed inland, annexing the sugar plantations that surrounded it. In order to supply the plantations with the manpower they required, a successful expedition was launched in 1637 from Brazil to capture the Portuguese slaving post of Elmina, and in 1641 successfully captured the Portuguese settlements in Angola. In 1642, the Dutch captured the Portuguese possession of Axim in Africa. By 1650, the West India Company was firmly in control of both the sugar and slave trades, and had occupied the Caribbean islands of Sint Maarten, Curacao, Aruba and Bonaire in order to guarantee access to the islands' salt-pans.
Question: What were two things the West India Company desired? | [
"sugar and slave trades"
] | task469-0b088d47f6b34c83a2e8835c78f4c454 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Sports City Stadium is a proposed football stadium which will be built in Doha, Qatar in time for the 2022 FIFA World Cup in Qatar.
Question: What team uses Sports City Stadium? | [
"2022 fifa world cup"
] | task469-6346339c853e4f209082fa7478315ba7 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Hoping to build on their home win over the Jets, the Browns flew to Qualcomm Stadium to take on the throwback-clad San Diego Chargers. In the first quarter, things started off close with Chargers kicker Nate Kaeding getting a 29-yard field goal, while Browns kicker Phil Dawson nailed a 37-yarder. In the second quarter, Dawson would get a 20-yard field goal for Cleveland. However, San Diego got the first touchdown of the game, as LB Marques Harris recovered a fumble in the Browns endzone for a touchdown. Dawson would supply the scoring for Cleveland for the rest of the half, as he nailed a 42-yarder and a 30-yarder. In the third quarter, the Chargers gained some momentum, as RB LaDainian Tomlinson, after getting bottled up in the first half, broke out with a 41-yard TD run for the only score of the period. In the fourth quarter, Dawson would get another field goal, which came from 36 yards out. However, San Diego would respond with Tomlinson getting a 7-yard TD run. Cleveland would have Dawson get a 35-yard field goal, yet Tomlinson would get an 8-yard TD run, which was followed by a successful two-point conversion from QB Philip Rivers to WR Vincent Jackson. The Browns would finally get a touchdown, as QB Charlie Frye completed a 4-yard TD pass to WR Braylon Edwards. Unfortunately, the damage was already done. With the loss, Cleveland would fall to 2-6.
Question: Which kicker made the second longest field goal? | [
"phil dawson"
] | task469-acd2d658866b49f6951c1e5cec294442 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: In the last few years, several tyrosine kinase inhibitors (TKIs) have been synthesized and become available for preclinical studies and clinical trials. This article summarizes recent achievements in the mechanism of action, pharmacological properties, and clinical activity and toxicity, as well as the emerging role of TKIs in lymphoid malignancies, allergic diseases, and autoimmune disorders. A literature review was conducted of the MEDLINE database PubMed for articles in English. Publications from 2000 through January 2012 were scrutinized. The search terms used were Bruton's tyrosine kinase (Btk) inhibitors, PCI-32765, GDC-0834, LFM-A13, AVL-101, AVL-292, spleen tyrosine kinase (Syk) inhibitors, R343, R406, R112, R788, fostamatinib, BAY-61-3606, C-61, piceatannol, Lyn, imatinib, nilotinib, bafetinib, dasatinib, GDC-0834, PP2, SU6656 in conjunction with lymphoid malignancy, NHL, CLL, autoimmune disease, allergic disease, asthma, and rheumatoid arthritis. Conference proceedings from the previous 5 years of the American Society of Hematology, European Hematology Association, American Society of Clinical Oncology, and ACR/ARHP Annual Scientific Meetings were searched manually. Additional relevant publications were obtained by reviewing the references from the chosen articles. The use of TKIs, especially inhibitors of Btk, Syk, and Lyn, is a promising new strategy for targeted treatment of B-cell lymphoid malignancies, autoimmune disorders and allergic diseases. However, definitive data from ongoing and future clinical trials will aid in better defining the status of TKIs in the treatment of these disorders.
Question: Which enzyme is inhibited by a drug fostamatinib? | [
"spleen tyrosine kinase"
] | task469-a02c531c18b44f04a68f0a0f0d40774d | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Harvey Shine (Dustin Hoffman) works as a jingle writer for television commercials in Manhattan, a job not in keeping with his one-time aspiration to be a jazz composer and pianist. We see him at work and he is very good at what he does. However, his boss does not seem impressed with his latest output. As Harvey departs for London to attend his daughter Susan's wedding, his boss actually suggests that he spend more time there than he had originally planned. Harvey declines, making the point that he needs to be back for an upcoming pitch to an old client. His boss insists that it is being done by other musicians, and that Harvey's latest work was his last chance to keep his job.On the plane, Harvey tries to chat up a fellow passenger, but she is having none of it. He is left sitting there with egg on his face and we come to regard him as even more of a loser.Meanwhile, we witness the mildly strained relationship between Kate Walker (Emma Thompson), a single Londoner, and her mother, whose husband left years earlier. Kate tries to reassure her mother that despite being single, she may yet find a man. Further, Kate tells her mom to quit worrying about the new Polish neighbor who has moved in next door and seems to be stacking a lot of firewood.Upon arrival at Heathrow Airport in London, Harvey encounters Kate at her job collecting statistics from passengers as they pass through the terminals. She attempts to question him about his reasons for visiting the UK. Tired and anxious to get to his hotel, Harvey brusquely dismisses her when she approaches him to ask questions.Harvey heads for the hotel to check in and discovers that he is the first one to arrive. Upon calling his daughter to double check where everyone else is when they were all supposed to be staying together, he learns that his ex-wife Jean actually rented a house to accommodate family and friends from the States and he is the only one at the hotel.After a brief nap, he showers and hurriedly dresses. On the way to the rehearsal dinner in the taxi cab, he realizes the anti-shoplifting device is still attached to the sleeve of his jacket. And to make matter worse, he has worn a white suit (thinking this was requested) while all the other men wore black. During the meal, it becomes increasingly clear Harvey is considered a mere guest and the role of father of the bride has been delegated to Jean's husband Brian. To add insult to injury, Brian stands to give the toast, and recollects the vacation they all spent in Rome, and his stepson-in-law-to-be embraces him and calls him Dad. Just before leaving back to his hotel, when Harvey tells Susan (with whom he has shared a strained relationship since his divorce) that he will be attending the ceremony but not the subsequent reception because he needs to return to the States for an important meeting, she informs him she has asked Brian to give her away.Meanwhile, Kate is set up on a blind date by a well meaning co-worker that does not go well. When she returns to the table after taking yet another call from her mother, she discovers her younger date has invited some of his younger friends to join them. Feeling unwanted and excluded from the conversation, she eventually excuses herself and goes home. As it turns out, Kate's increasingly neurotic mother seems convinced that her Polish neighbor is some kind of murderer because she sees him toting strange looking, lumpy packages into a shed in the back yard.The following morning Harvey attends Susan's wedding, but heavy traffic delays his arrival back to Heathrow, and he misses his plane. When he calls his boss Marvin in NYC to inform him he will be returning a day later than planned and that he will try to get there as soon as possible, he is told that he is fired.In his glum mood, Harvey makes his way to the airport bar and starts slugging down scotch, determined to drown his sorrows. Kate is sitting in the lounge reading
Question: Who has Harvey had a strained relationship with since the divorce? | [
"susan"
] | task469-cdc21865620044d3893ff11d96f87f7f | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: After Alaungpaya's death, the new Burmese king Naungdawgyi was embroiled in several rebellions, including that of Gen. Minkhaung Nawrahta, and could not resume the war. The war was inconclusive. For all their work, the Burmese gained little of their original objectives. Siam very much remained a thorn to the stability of Burmese peripheral regions. In the following years, Siam continued to provide support to Mon rebels in the south who raised a major rebellion in 1762 as well as those in Lan Na in the north . The only lasting territorial gain the Burmese achieved was the upper Tenasserim coast, on which they previously had only a nominal claim. Although the Siamese troops no longer openly intruded the border, the Mon rebels continued to operate from the Siamese territory. In 1764, the Mon governor of Tavoy, who was made governor by Alaungpaya only four years earlier, revolted until it was put down in November 1764. Likewise, the instabilities in Lan Na resumed soon after the Burmese army left in February 1764, forcing the army to return again later in the year. The inconclusive nature of the war would lead to the next war in 1765.
Question: hich happened first, the nominal claim of the Burmese on the Tenasserim coast, or a territorial claim? | [
"a nominal claim"
] | task469-4bd45df2f82e4e32ac11d51a7f6034a2 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: In a New York City residence, Pierre Delacroix (Damon Wayans) rises to begin his daily routine. Brushing his teeth, he gives us by voice over a definition of satire. He tells us that with the rise of the Internet, video and interactive games, his field as a television writer has seen a drop in popularity. Meanwhile, in a dilapidated building, squatter Womack (Tommy Davidson) wakes up his friend Manray (Savion Glover) for a day of work. This consists of travelling to the CNS (Continental Network System) building where Delacroix works, and Manray tap dancing to entertain the workers. They then collect money from the workers. The men see Delacroix walk by, and ask him for monetary help in the form of work of some kind.Delacroix walks into a staff meeting late and is immediately castigated by his boss, Thomas Dunwitty (Michael Rapaport). Dunwitty informs the staff that CNS has poor ratings. He says he wants them to write funnier material, and ends the meeting. In the privacy of his office, Dunwitty tells Delacroix that the material Delacroix's been writing for him seems like it's about white people with black faces. Dunwitty asserts that Delacroix is an "oreo" with his Harvard education, because he won't write a "n----r show."The next day, Delacroix and his assistant Sloan Hopkins (Jada Pinkett Smith) talk. They've decided that Manray is the solution to his problem. Delacroix plans to write a show that will be so "offensive and racist," it will prove his point that the network only wants to see black buffoons on the air. Delacroix simply hopes to be fired, so he can be let go of his contract with CNS. Manray and Womack ask at the receptionist's desk for a "Delapoint" and the men working there tell them to step outside. However, Sloan steps into the lobby, sees what's happening, and escorts Manray and Womack to Delacroix's office. Delacroix explains to them that he has an idea for a television pilot, and they can make money with it. His main request is that Manray changes his name to Mantan, in an apparent homage to black character actor Mantan Moreland.On Sloan's walk home, she runs into her big brother Big Blak Afrika F/K/A Julius (Yasiin Bey). In Sloan's apartment, Julius and Sloan argue about his values, and he tells her to introduce him and his political hip-hop crew, the Mau Maus, to Delacroix.Delacroix has another meeting with Dunwitty. Delacroix proposes that the network start a variety show called "Mantan: The New Millenium Minstrel Show." Delacroix says that new faces are needed for the show, and has Sloan bring in Manray and Womack. The two men, respectively renamed "Mantan" and "Sleep'n Eat," will exhibit a range of stereotypical traits, Delacroix explains. Sloan is opposed to the proceedings, and suggests that there will be protest of the show they are planning. To seal the package, Manray dances atop a table in front of Dunwitty -- who immediately leaves to try to sell the show's concept to his executive bosses.Delacroix, Sloan and another woman hold auditions for the show. The first group of people (The Roots) audition to be the show's house band, The Alabama Porch Monkeys. After they perform, a dancer, a vulgar man shouting "I be smackin' my hoes," and a didgeridoo player all audition. The next hopeful is Honeycutt (Thomas Jefferson Byrd), an actor who bungles Shakespearean quotes and proclaims "N----s is a beautiful thing." Sloan's brother's group, the Mau Maus then do a fiery, confrontational performance; Pierre states via voice over that there is no place for them in his plan.Delacroix looks over a revised script for the show and confronts Dunwitty and his co-writer, Jukka about their alterations to it that even he finds racially offensive. Delacroix says that he won't be responsible for their changes, which Dunwitty says are to make the show funnier. Dunwitty says he knows black people better than Delacroix does, telling him, "Look
Question: Who is Delacroix's personal assistant? | [
"sloan hopkins"
] | task469-c2b3bcfd7e794e0eab3fb32bf2d410af | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Nutrients in the foods you eat are needed by the cells of your body. How do the nutrients in foods get to your body cells? What organs and processes break down the foods and make the nutrients available to cells? The organs are those of the digestive system. The processes are digestion and absorption. The digestive system is the body system that breaks down food and absorbs nutrients. It also gets rid of solid food waste. The digestive system is mainly one long tube from the mouth to the anus, known as the gastrointestinal tract (GI tract). The main organs of the digestive system include the esophagus, stomach and the intestine, and are pictured below ( Figure 1.1). The intestine is divided into the small and large intestine. The small intestine has three segments. The ileum is the longest segment of the small intestine, which is well over 10 feet long. The large intestine is about 5 feet long. This drawing shows the major organs of the digestive system. The liver, pancreas and gallbladder are also organs of the digestive system. Digestion is the process of breaking down food into nutrients. There are two types of digestion, mechanical and chemical. In mechanical digestion, large chunks of food are broken down into small pieces. Mechanical digestion begins in the mouth and involves physical processes, such as chewing. This process continues in the stomach as the food is mixed with digestive juices. In chemical digestion, large food molecules are broken down into small nutrient molecules. This is a chemical process which also begins in the mouth as saliva begins to break down food and continues in the stomach as stomach enzymes further digest the food. Absorption is the process that allows substances you eat to be taken up by the blood. After food is broken down into small nutrient molecules, the molecules are absorbed by the blood. After absorption, the nutrient molecules travel in the bloodstream to cells throughout the body. This happens mostly in the small intestine. Some substances in food cannot be broken down into nutrients. They remain behind in the digestive system after the nutrients are absorbed. Any substances in food that cannot be digested and absorbed pass out of the body as solid waste. The process of passing solid food waste out of the body is called elimination.
Question: another name for the digestive tube is the | [
"gastrointestinal tract."
] | task469-3b223cb5502a40f0866f716874ef2a1c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: As of May, 2010, the California Secretary of State reports that San Benito County has 34,562 eligible voters. Of those 24,736 (71.57%) are registered voters. Of those, 11,959 (48.35%) are registered Democratic, 7,477 (30.23%) are registered Republican, 565 (2.28%)are registered American Independent, and 116 (0.47%) are Green Party. The two incorporated municipalities of Hollister and San Juan Bautista have Democratic majorities on their voter rolls, whereas the unincorporated areas of San Benito County have a small Republican plurality in voter registration.
Question: Are there more registered American Independent or Green Party voters? | [
"american independent"
] | task469-102edc0180334d5a8eea29b9ee21262c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Somewhere in harbourside Sydney, Australia, a family lives within a high-rise apartment building where the mother is preparing a meal and listening to the radio. Her fourteen year old daughter (Jenny Agutter) and six year old son (Luc Roeg) swim in the building's pool overlooking a view of the ocean while their father (John Meillon), deep in troubled thought, watches them from their balcony.One day, the father takes his children, still in their school uniforms, on a picnic into the Outback. He parks the car and reads while his daughter sets up a blanket with their lunch. Her brother plays nearby with his water gun and toy soldiers. Suddenly, and for reasons unclear to his children, the father announces it is time to go and brandishes a gun, firing several shots at them. The boy thinks it all to be a game but his sister understands the danger and shields her brother as they run from their mad father. She watches in horror as her father returns to the car and sets it on fire before seating himself within and putting a bullet into his head. Quickly, and keeping her brother's eyes averted, the girl retrieves their radio, a scarf, and what food she can carry before setting off into the wilderness with her brother.The siblings walk for hours under the hot sun, calmed by irrelevant radio broadcasts, and walking past a host of wild creatures. Come nightfall, they make a crude camp for themselves, much to the boy's delight. In the morning, the girl leads them up a rocky hillside where she hopes to find some bearings. However, she can see nothing but a broad spanse of wilderness. When they finish their lemonade, the girl opens a can of vegetables from which they drink the juice. Recalling an uncle's story of military training, the girl suggests they eat salt to retain water and surmises to her brother that they may spend some time in the desert. She remains stoic, but wary, while her brother is blissfully unaware of their situation, remaining entertained by the radio and his toys. Eventually, after becoming filthy and tired, they come upon a lone tree standing over a pool of water where parakeets flock and feast on fallen fruit. The boy puts on in his mouth and proclaims that it 'tastes lovely'. They wash in the water and the girl scolds her brother to take care of his clothes so they will last. When he asks if they are lost, the girl replies that they are not, trying to remain chipper. They sleep to the sounds of the radio as night animals stir around them.In the morning, the girl wakes to find that their water hole has dried up and the fruit has either been eaten or spoiled. The girl decides to remain where they are, hoping that the water will return. As they nap in the hot sun, the boy spots an aborigine youth (David Gulpilil) pursuing an animal for food. They make contact and the children attempt to communicate with the aborigine boy. However, he does not understand their language and merely stares at them with curiosity. The girl repeats their need for water but the word is incomprehensible to the aborigine. When her brother mimics drinking, the aborigine understands and shows them how to dig for water using a hollow tube to drink through. Assuming that he will lead them to civilization, the siblings accompany the aborigine, unaware that he is on a 'walkabout', a coming-of-age journey that every male aborigine youth must take alone in order to be initiated as an adult in his tribe.As they travel the Outback, the aborigine kills and harvests food for them, giving them all plenty to eat and drink. The move from the desert to greener pastures and forests where wildlife becomes plentiful. When the boy becomes sunburnt from going shirtless, the aborigine rubs pig fat on his back to alleviate the burn. While communication between them remains limited, the trio share food and play together, though cultural differences are evident; the boy attempts to share his toy soldiers with the aborigine, but he finds no use for them and tosses
Question: What does the Aboriginal boy hunt down ? | [
"the aboriginal boy hunts down a water buffalo",
"an animal"
] | task469-1fe019ee06af4d49b3943d9c5169820d | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Calculating acceleration is complicated if both speed and direction are changing or if you want to know acceleration at any given instant in time. However, its relatively easy to calculate average acceleration over a period of time when only speed is changing. Then acceleration is the change in velocity (represented by v) divided by the change in time (represented by t): acceleration = v t Look at the cyclist in the Figure 1.1. With the help of gravity, he speeds up as he goes downhill on a straight part of the trail. His velocity changes from 1 meter per second at the top of the hill to 6 meters per second by the time he reaches the bottom. If it takes him 5 seconds to reach the bottom, what is his average acceleration as he races down the hill? v t 6 m/s 1 m/s = 5s 5 m/s = 5s 1 m/s = 1s = 1 m/s2 acceleration = In words, this means that for each second the cyclist travels downhill, his velocity (in this case, his speed) increases by 1 meter per second on average. Note that the answer to this problem is expressed in m/s2 , which is the SI unit for acceleration. Q: The cyclist slows down at the end of the race. His velocity changes from 6 m/s to 2 m/s during a period of 4 seconds without any change in direction. What was his average acceleration during these 4 seconds? A: Use the equation given above for acceleration: v t 6 m/s 2 m/s = 4s 4 m/s = 4s 1 m/s = 1s = 1 m/s2 acceleration =
Question: the si unit for acceleration is | [
"m/s2."
] | task469-b0e8dcafc09a41e6a00d121ebe51973a | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Stem cells, one of the progenitors of cancer, exist predominately in a quiescent state. Thus, understanding the mechanisms of DNA repair and mutagenesis in such arrested cells may help unravel the complex process of tumorigenesis. Two major nucleotide excision repair (NER) pathways are known to remove bulky physical or chemical lesions from DNA. Transcription-coupled repair (TCR) acts solely on the transcribed strand of expressed genes, while global genomic repair (GGR) is responsible for the ubiquitous repair of the genome. Indirectly, it has been shown that while TCR functions in quiescent cells GGR does not. To explicitly elucidate this phenomenon, we adapted a quantitative PCR (QPCR) assay to study UV-damage repair via TCR and GGR in quiescent and proliferating cells. We present evidence that repair of untranscribed silent regions of the genome and repair of the non-transcribed strand of active genes proceeds by two discrete mechanisms in quiescent cells; rather than by GGR, which was believed to encompass both. Thus, our findings suggest the existence of an alternate NER pathway in quiescent cells. The proposed subcategories of NER are as follows: (i) TCR, responsible for maintenance of transcribed strands; (ii) GGR, responsible for ubiquitous genome repair; and (iii) non-transcribed strand repair (NTSR), predominantly responsible for the repair of the NTS in arrested cells. In quiescent cells, it is evident that TCR and NTSR function and GGR are arrested. As a consequence, mutation accumulation at temporally silent genes and incomplete or imperfect repair of transcribed genes, in quiescent stem cells, may provide a source of cancer causing mutations.
Question: Which gene strand is targeted by transcription-coupled repair (TCR)? | [
"the transcribed strand"
] | task469-db3e4306a1cf49b688be19168dc1bf6c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Yosemite Sam is on the hunt for a rabbit, and smells Bugs cooking carrots over a rotisserie. When an audience member attempts to leave, Yosemite Sam forces him back into his seat at gunpoint and breaks the fourth wall, threatening to kill anyone who tries to leave the theatre, fearing they could spoil his plan.Sam corners Bugs, and tells him he will be killed at the count of 10. During the countdown, Bugs takes out a piece of bubble gum, chews it, and jams Sam's rifle with it. When Sam fires, he is enveloped in a bubble gum bubble. The bubble is virtually weightless and highly durable; Bugs blows it away, and it falls over a cliff. Sam frantically blows upward, which causes the bubble to stop falling and drift up again. However, Bugs is waiting at the top of the cliff, and he uses a pin to burst the bubble. Sam is enveloped in the sticky remains of the bubble, and sticks to the ground when he falls, bouncing upward repeatedly.Sam chases after Bugs again, managing to get the bubble gum off his body. He forces Bugs out of his hole with a shovel, and marches him to his house at gunpoint.Sam prepares to cook Bugs in a wood stove. Bugs throws Sam's hat into the fire, but when Sam goes to retrieve it, he retrieves a piece of burning firewood by mistake. He quickly gets his hat again, and orders Bugs into the oven (again at gunpoint). While Sam sets the table, he is surprised to find Bugs calmly exiting the oven, retrieving a pitcher of water and a fan, and stepping inside again. Sam is not pleased, but Bugs opens the door again and asks for a bottle opener, which Sam gives to him. The sounds of a party can be heard inside the oven.Bugs exits the oven again to get some ice and chairs, then returns once more and empties two full ashtrays into Sam's hat. When Bugs emerges for the fifth time, he is covered with lipstick marks, and tells Sam plenty of girls are waiting for him inside. Sam quickly puts on a bowtie, and steps into the oven, prompting Bugs to slam the door. Bugs "warms the party up" by throwing some more firewood into the stove, but then decides he's gone too far with this prank.He opens the oven door to tell Sam about the prank, but is flabbergasted to find an actual party taking place inside the oven. He excitedly dives into the oven to join the party, emerging one more time to quip to the audience, "I don't ask questions, I just have fun!" Iris out.
Question: What is the bubble that surrounds Sam is made of? | [
"bubble gum"
] | task469-630523baa0464cb8b7699efdc4813cf2 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Darwins theory of evolution by natural selection contains two major ideas: One idea is that evolution happens. Evolution is a change in the inherited traits of organisms over time. Living things have changed as descendants diverged from common ancestors in the past. The other idea is that evolution occurs by natural selection. Natural selection is the process in which living things with beneficial traits produce more offspring. As a result, their traits increase in the population over time. How did Darwin come up with the theory of evolution by natural selection? A major influence was an amazing scientific expedition he took on a ship called the Beagle. Darwin was only 22 years old when the ship set sail. The trip lasted for almost five years and circled the globe. Figure 7.2 shows the route the ship took. It set off from Plymouth, England in 1831. It wouldnt return to Plymouth until 1836. Imagine setting out for such an incredible adventure at age 22, and youll understand why the trip had such a big influence on Darwin. Darwins job on the voyage was to observe and collect specimens whenever the ship went ashore. This included plants, animals, rocks, and fossils. Darwin loved nature, so the job was ideal for him. During the long voyage, he made many observations that helped him form his theory of evolution. Some of his most important observations were made on the Galpagos Islands. The 16 Galpagos Islands lie 966 kilometers (about 600 miles) off the west coast of South America. (You can see their location on the map in Figure 7.2.) Some of the animals Darwin observed on the islands were giant tortoises and birds called finches. Watch this video for an excellent introduction to Darwin, his voyage, and the Galpagos: The Galpagos Islands are still famous for their giant tortoises. These gentle giants are found almost nowhere else in the world. Darwin was amazed by their huge size. He was also struck by the variety of shapes of their shells. You can see two examples in Figure 7.3. Each island had tortoises with a different shell shape. The local people even could tell which island a tortoise came from based on the shape of its shell. Darwin wondered how each island came to have its own type of tortoise. He found out that tortoises with dome- shaped shells lived on islands where the plants they ate were abundant and easy to reach. Tortoises with saddle- shaped shells, in contrast, lived on islands that were drier. On those islands, food was often scarce. The saddle shape of their shells allowed tortoises on those islands to reach up and graze on vegetation high above them. This made sense, but how had it happened? Darwin also observed that each of the Galpagos Islands had its own species of finches. The finches on different islands had beaks that differed in size and shape. You can see four examples in Figure 7.4. Darwin investigated further. He found that the different beaks seemed to suit the birds for the food available on their island. For example, finch number 1 in Figure 7.4 used its large, strong beak to crack open and eat big, tough seeds. Finch number 4 had a long, pointed beak that was ideal for eating insects. This seemed reasonable, but how had it come about? Besides his observations on the Beagle, other influences helped Darwin develop his theory of evolution by natural selection. These included his knowledge of plant and animal breeding and the ideas of other scientists. Darwin knew that people could breed plants and animals to have useful traits. By selecting which individuals were allowed to reproduce, they could change an organisms traits over several generations. Darwin called this type of change in organisms artificial selection. You can see an example in Figure 7.5. Keeping and breeding pigeons was a popular hobby in Darwins day. Both types of pigeons in the bottom row were bred from the common rock pigeon at the top of the figure. There were three other scientists in particular that influenced Darwin. Their names are Lamarck, Lyell, and Malthus. All three were somewhat older than Darwin, and he was familiar with their writings. Jean Baptiste Lamarck was a French naturalist
Question: Onboard the Beagle, Darwin served as the ships | [
"naturalist"
] | task469-48f72ed38d1e4b978374448c338b93ad | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: In nuclear fusion, two or more small nuclei combine to form a single, larger nucleus. You can see an example in the Figure 1.1. In this example, nuclei of two hydrogen isotopes (tritium and deuterium) fuse to form a helium nucleus. A neutron and a tremendous amount of energy are also released. Nuclear fusion of hydrogen to form helium occurs naturally in the sun and other stars. It takes place only at extremely high temperatures. Thats because a great deal of energy is needed to overcome the force of repulsion between the positively charged nuclei. The suns energy comes from fusion in its core, shown in the Figure 1.2. In the core, temperatures reach millions of degrees Kelvin. Click image to the left or use the URL below. URL: The Sun Q: Why doesnt nuclear fusion occur naturally on Earth? A: Nuclear fusion doesnt occur naturally on Earth because it requires temperatures far higher than Earth tempera- tures. Scientists are searching for ways to create controlled nuclear fusion reactions on Earth. Their goal is develop nuclear fusion power plants, where the energy from fusion of hydrogen nuclei can be converted to electricity. You can see how this might work in the Figure 1.3. In the thermonuclear reactor, radiation from fusion is used to heat water and produce steam. The steam can then be used to turn a turbine and generate electricity. The use of nuclear fusion for energy has several pros. Unlike nuclear fission, which involves dangerous radioactive elements, nuclear fusion involves just hydrogen and helium. These elements are harmless. Hydrogen is also very plentiful. There is a huge amount of hydrogen in ocean water. The hydrogen in just a gallon of water could produce as much energy by nuclear fusion as burning 1,140 liters (300 gallons) of gasoline! The hydrogen in the oceans would generate enough energy to supply all the worlds people for a very long time. Unfortunately, using energy from nuclear fusion is far from a reality. Scientists are a long way from developing the necessary technology. One problem is raising temperatures high enough for fusion to take place. Another problem is that matter this hot exists only in the plasma state. There are no known materials that can contain plasma, although a magnet might be able to do it. Thats because plasma consists of ions and responds to magnetism. Click image to the left or use the URL below. URL:
Question: nuclear fusion occurs inside | [
"stars."
] | task469-54c219204ccd4f5ab94301177e7eaa7c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: When you take a walk along a beach, what do you find there? Sand, the ocean, lots of sunlight. You may also find shells. The shells you find are most likely left by organisms in the phylum Mollusca. On the beach, you can find the shells of many different mollusks ( Figure 1.1), including clams, mussels, scallops, oysters, and snails. Mollusks are invertebrates that usually have a hard shell, a mantle, and a radula. Their glossy pearls, mother of pearl, and abalone shells are like pieces of jewelry. Some mollusks, such as squid and octopus, do not have shells. The Mollusks body is often divided into different parts ( Figure 1.2): On the beach, you can find a wide variety of mollusk shells. 1. A head with eyes or tentacles. 2. In most species, a muscular foot, which helps the mollusk move. Some mollusks use the foot for burrowing into the sand, and others use it for jet-propulsion. 3. A mantle, or fold of the outer skin lining the shell. The mantle often releases calcium carbonate, which creates an external shell, just like the ones you find on the beach. The shell is made of chitin, a tough, semitransparent substance. 4. A mass housing the organs. 5. A complete digestive tract that begins at the mouth and runs to the anus. 6. Most ocean mollusks have a gill or gills to absorb oxygen from the water. 7. Many species have a feeding structure, the radula, found only in mollusks. The radula can be thought of as a "tongue-like" structure. The radula is made mostly of chitin. Types of radulae range from structures used to scrape algae off of rocks to the beaks of squid and octopuses. This is the basic body plan of a mollusk. Note the mantle, gills, and radula. Keep in mind the basic body plan can differ slightly among the mollusks. Mollusks are probably most closely related to organisms in the phylum Annelida, also known as segmented worms. This phylum includes the earthworm and leech. Scientists believe these two groups are related because, when they are in the early stage of development, they look very similar. Mollusks also share features of their organ systems with segmented worms. Unlike segmented worms, however, mollusks do not have body segmentation. The basic mollusk body shape is usually quite different as well.
Question: what type of worms are most closely related to mollusks? | [
"segmented worms"
] | task469-d838624544e14cbca15c5c7bf7be4dcb | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: People from all over the world visit Disneyland to have fun, not to get sick. But last week, an outbreak of measles spread from the Southern California theme park. As of Monday, January 19, at least 52 people have got the easily spread illness. The majority of the reported cases of measles are from people who visited the park before. According to the California Department of Public Health, these people were exposed to the illness at Disneyland from December 17-20. Officials believe the cause is likely someone who caught measles abroad and visited Disneyland, but this has yet to be proved. However, in 2014, California had its highest measles infection rate in nearly twenty years. There were 66 cases of measles reported in the state--23 of them in Orange County, where Disneyland is located. Measles spreads very easily. It can be caught from coughing and sneezing. Crowded areas like theme parks are especially suitable for its spread. The illness starts with a fever and develops into symptoms including a cough, runny nose, red eyes and so on. About three out of ten people infected with measles will develop another health problem, including an ear infection or pneumonia . The best way to _ measles is to get vaccinated . An unvaccinated person is 35 times more likely to catch measles than someone who received a vaccination.
Question: How many people suffered from measles in California in 2014? | [
"66"
] | task469-4a087803201443ca80b815639a614739 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Chevrolet Equinox is a mid-size crossover SUV from Chevrolet based on General Motors's Theta unibody platform, manufactured at CAMI Automotive (formerly a GM/Suzuki joint venture, now wholly owned by GM) plant in Ingersoll, Ontario, Canada, and introduced in 2004 for the 2005 model year.
Question: Which company manufactured Chevrolet Equinox? | [
"general motors"
] | task469-9672a8d2070d46f6aaf4b07676fd0886 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: In a New York City courthouse, an eighteen-year-old boy from a slum is on trial for allegedly stabbing his father to death. Final closing arguments having been presented, a visibly bored judge instructs the jury to decide whether the boy is guilty of murder. If there is any reasonable doubt of his guilt they are to return a verdict of not guilty. The judge further informs them that a guilty verdict will be accompanied by a mandatory death sentence.The jury retires to a private room, where the jurors spend a short while getting acquainted before they begin deliberating. It is immediately apparent that the jurors have already decided that the boy is guilty, and that they plan to return their verdict without taking time for discussion with the sole exception of Juror 8 (Henry Fonda), who is the only "not guilty" vote in a preliminary tally. He explains that there is too much at stake for him to go along with the verdict without at least talking about it first. His vote annoys the other jurors, especially Juror 7 (Jack Warden), who has tickets to a baseball game that evening; and Juror 10 (Ed Begley Sr.), who believes that people from slum backgrounds are liars, wild, and dangerous.The rest of the film's focus is the jury's difficulty in reaching a unanimous verdict. While several of the jurors harbor personal prejudices, Juror 8 maintains that the evidence presented in the case is circumstantial, and that the boy deserves a fair deliberation. He calls into question the accuracy and reliability of the only two witnesses to the murder, the "rarity" of the murder weapon (a common switchblade, of which he has an identical copy), and the overall questionable circumstances. He further argues that he cannot in good conscience vote "guilty" when he feels there is reasonable doubt of the boy's guilt.Having argued several points and gotten no favorable response from the others, Juror 8 reluctantly agrees that he has only succeeded in hanging the jury. Instead, he requests another vote, this time by secret ballot. He proposes that he will abstain from voting, and if the other 11 jurors are still unanimous in a guilty vote, then he will acquiesce to their decision. The secret ballot is held, and a new "not guilty" vote appears. This earns intense criticism from Juror 3 (Lee J. Cobb), who blatantly accuses Juror 5 (Jack Klugman) who had grown up in a slum of switching out of sympathy toward slum children. However, Juror 9 (Joseph Sweeney) reveals that he himself changed his vote, feeling that Juror 8's points deserve further discussion.Juror 8 presents a convincing argument that one of the witnesses, an elderly man who claimed to have heard the boy yell "I'm going to kill you" shortly before the murder took place, could not have heard the voices as clearly as he had testified due to an elevated train passing by at the time; as well as stating that "I'm going to kill you," is often said by people who do not literally mean it. Juror 5 changes his vote to "not guilty". Soon afterward, Juror 11 (George Voskovec) questions whether it is reasonable to suppose the defendant would have fled the scene, having cleaned the knife of fingerprints but leaving it behind, and then come back three hours later to retrieve it (having been left in his father's chest). Juror 11 then changes his vote.Juror 8 then mentions the man's second claim: upon hearing the father's body hit the floor, he had run to the door of his apartment and seen the defendant running out of the building from his front door in 15 seconds. Jurors 5, 6 and 8 question whether this is true, as the witness in question had had a stroke, limiting his ability to walk. Upon the end of an experiment, the jury finds that the witness would not have made it to the door in enough time to actually see the killer running out. Juror 8 concludes that, judging from what he claims to have heard earlier, the witness must have
Question: In which city courthouse the case of the boy commences? | [
"new york city"
] | task469-e0b1e70657024b1fb2473e7b25d23b45 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Lufthansa's secondary hub is Munich Airport.
Question: Which airport is most closely associated with Lufthansa? | [
"munich airport"
] | task469-e68e1281e5e64e9395059b52bc3ff2c8 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Redskins primary weapon in the backfield was running back Earnest Byner, who ranked 5th in the NFL with 1,048 rushing yards, while also catching 34 passes for 308 yards and scoring 5 touchdowns. Rookie running back Ricky Ervins was also a major asset to the running attack, rushing 145 times for 680 yards for an average of 4.7 yards per carry, while also catching 16 passes for 181 yards. And when Washington was near the goal line, they usually relied on fullback Gerald Riggs, who rushed for 248 yards and scored 11 touchdowns. The Redskins offensive line, known as "The Hogs (American football)", was led by Pro Bowl tackle Jim Lachey and guard Mark Schlereth, along with four-time Pro Bowl veteran Russ Grimm. The Hogs allowed the fewest sacks in the league with just 9, 10 sacks less than the team that allowed the second-fewest. Even Washingtons special teams unit was a big threat. Running back Brian Mitchell (running back) led the NFL in punt return yards (600) and punt return touchdowns (2) with a 13.3 yards per return average, while also gaining 583 yards returning kickoffs.
Question: Which player had more rushing yards, Ricky Ervins or Earnest Byner? | [
"earnest byner,"
] | task469-5129b4c3286941c78126b5752ea3a48c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Asexual reproduction is simpler than sexual reproduction. It involves just one parent. The offspring are genetically identical to each other and to the parent. All prokaryotes and some eukaryotes reproduce this way. There are several different methods of asexual reproduction. They include binary fission, fragmentation, and budding. Binary fission occurs when a parent cell simply splits into two daughter cells. This method is described in detail in the lesson "Cell Division." Bacteria reproduce this way. You can see a bacterial cell reproducing by binary fission in Figure 5.9. Fragmentation occurs when a piece breaks off from a parent organism. Then the piece develops into a new organism. Sea stars, like the one in Figure 5.10, can reproduce this way. In fact, a new sea star can form from a single arm. Budding occurs when a parent cell forms a bubble-like bud. The bud stays attached to the parent while it grows and develops. It breaks away from the parent only after it is fully formed. Yeasts can reproduce this way. You can see two yeast cells budding in Figure 5.11. Sexual reproduction is more complicated. It involves two parents. Special cells called gametes are produced by the parents. A gamete produced by a female parent is generally called an egg. A gamete produced by a male parent is usually called a sperm. An offspring forms when two gametes unite. The union of the two gametes is called fertilization. You can see a human sperm and egg uniting in Figure 5.12. The initial cell that forms when two gametes unite is called a zygote. In species with sexual reproduction, each cell of the body has two copies of each chromosome. For example, human beings have 23 different chromosomes. Each body cell contains two of each chromosome, for a total of 46 chromosomes. You can see the 23 pairs of human chromosomes in Figure 5.13. The number of different types of chromosomes is called the haploid number. In humans, the haploid number is 23. The number of chromosomes in normal body cells is called the diploid number. The diploid number is twice the haploid number. In humans, the diploid number is two times 23, or 46. The two members of a given pair of chromosomes are called homologous chromosomes. We get one of each homologous pair, or 23 chromosomes, from our father. We get the other one of each pair, or 23 chromosomes, from our mother. A gamete must have the haploid number of chromosomes. That way, when two gametes unite, the zygote will have the diploid number. How are haploid cells produced? The answer is meiosis. Meiosis is a special type of cell division. It produces haploid daughter cells. It occurs when an organism makes gametes. Meiosis is basically mitosis times two. The original diploid cell divides twice. The first time is called meiosis I. The second time is called meiosis II. However, the DNA replicates only once. It replicates before meiosis I but not before meiosis II. This results in four haploid daughter cells. Meiosis I and meiosis II occurs in the same four phases as mitosis. The phases are prophase, metaphase, anaphase, and telophase. However, meiosis I has an important difference. In meiosis I, homologous chromosomes pair up and then separate. As a result, each daughter cell has only one chromosome from each homologous pair. Figure 5.14 is a simple model of meiosis. It shows both meiosis I and II. You can read more about the stages below. You can also learn more about them by watching this video: . MEDIA Click image to the left or use the URL below. URL: After DNA replicates during interphase, the nucleus of the cell undergoes the four phases of meiosis I: 1. Prophase I: Chromosomes form, and the nuclear membrane breaks down. Centrioles move to opposite poles of the cell. Spindle fibers form between the centrioles. Heres whats special about meiosis: Homologous chromosomes pair up! You can see this in Figure below. 2. Metaphase I: Spindle fibers attach to the centromeres of the paired homologous chromosomes. The paired chromosomes line up at the center of
Question: The diploid number of chromosomes in a species is always | [
"twice the haploid number."
] | task469-0e980e9660c8406bb54f0c6ce7358b5c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Richard Donnevert (born 2 August 1896 in Mainz - died 27 January 1970 in Wiesbaden) was a German Nazi Party politician.
Question: What was the political party of Richard Donnevert? | [
"nazi party"
] | task469-6c97d6c25b2e4e4ea473b1a86c012b42 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The present case-control study was conducted to investigate the relationship between smoking and rheumatoid arthritis, and to investigate formally the interaction between sex, smoking, and risk for developing rheumatoid arthritis. The study was performed in the Central District of Finland. Cases were patients with rheumatoid arthritis and the control group was a random sample of the general population. Logistic regression models were used to evaluate the effect of smoking on risk for rheumatoid arthritis, after adjusting for the effects of age, education, body mass index, and indices of general health and pain. Overall, 1095 patients with rheumatoid arthritis and 1530 control individuals were included. Patients were older, less well educated, more disabled, and had poorer levels of general health as compared with control individuals (all P < 0.01). Preliminary analyses revealed the presence of substantial statistical interaction between smoking and sex (P < 0.001). In separate multivariable analyses, past history of smoking was associated with increased risk for rheumatoid arthritis overall in men (odds ratio 2.0, 95% confidence interval 1.2-3.2) but not in women. Among men, this effect was seen only for rheumatoid factor-positive rheumatoid arthritis. There were significant interactions between smoking and age among women but not among men. We conclude that sex is a biologic effect modifier in the association between smoking and rheumatoid arthritis. The role of menopause in the etiology of rheumatoid arthritis merits further research.
Question: Is Rheumatoid Arthritis more common in men or women? | [
"women"
] | task469-01f1b5ffc5d742b89ed5a9f0df7312e9 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Steelers stayed home for a 3-game home stand and for a Sunday Night duel against the Ravens. The Ravens scored first when Joe Flacco hooked up with Torrey Smith 35-yard TD pass to take a 7-0 lead for the only score of the first quarter. In the 2nd quarter, the Steelers managed to tie the game up when Ben Roethlisberger found Le'Veon Bell on a 5-yard TD pass for a 7-7 game. They eventually took the lead when Roethlisberger found Martavis Bryant on a 19-yard TD pass to make it a 14-7 game. The Ravens came within 4 as Justin Tucker kicked a 46-yard field goal to make it 14-10 game. However, the Steelers would manage to go ahead by 12 before halftime when Roethlisberger found Markus Wheaton on a 47-yard TD pass followed by a successful 2-point conversion for a 22-10 lead at halftime. After a scoreless 3rd quarter, the Steelers came out strong and went back to work in the 4th when Roethlisberger found Antonio Brown on a 54-yard TD pass making the score 29-10. The Ravens responded with a big play as Jacoby Jones ran a 108-yard kickoff return for a TD to make it a 29-17 game. Roethlisberger found Bryant again on an 18-yard TD pass to make the score 36-17. This was followed by the Ravens trying their hand at coming back when Flacco found Crockett Gillmore on a 1-yard TD pass (with a failed 2-point conversion) for a 36-23 score. But the Steelers were able to seal the game when Roethlisberger found Matt Spaeth on a 33-yard TD pass for a final score of 43-23. A week after passing for a franchise-record six touchdowns against Indianapolis, Roethlisberger duplicated the feat to lead Pittsburgh to its third consecutive win. The 12 touchdown passes over the last two games broke the NFL record of 11 set by Tom Flores for Oakland in the AFL in 1963 and matched by New England's Tom Brady in 2007.
Question: Which quarter had the most touchdowns scored? | [
"4th"
] | task469-f5b2ad823e8b43f2920ea267e3fde9e4 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: As of the census of 2000, there were 35,100 people, 12,759 households, and 9,071 families residing in the county. The population density was 59 people per square mile (23/km). There were 15,035 housing units at an average density of 25 per square mile (10/km). The racial makeup of the county was 85.8% Race (United States Census), 3.9% Race (United States Census) or Race (United States Census), 1.8% Race (United States Census), 1.0% Race (United States Census), 0.1% Race (United States Census), 5.0% from Race (United States Census), and 2.4% from two or more races. 8.9% of the population were Race (United States Census) or Race (United States Census) of any race. 14.9% were of German people, 12.6% English people, 11.7% Irish people, 8.8% Italian people and 7.3% United States ancestry according to Census 2000. 93.1% spoke English language and 5.1% Spanish language as their first language.
Question: Which population had the largest population total in the 2000 census, households or families? | [
"households"
] | task469-cb587d680c8f4f8f8f91b60b0c3fe370 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Ryu (Ha-kyun Shin), a deaf man, works in a factory to support his ailing sister (Ji-Eun Lim) in desperate need of a kidney transplant. Ryu tries to donate one of his kidneys to his sister but is told that his blood type does not match that of his sister and so is not a suitable donor. After being laid off from his job by the factory boss, Ryu contacts a black market organ dealer who agrees to sell him a kidney suitable for his sister in exchange for 10,000,000 Korean won, plus one of Ryu's own kidneys. He takes the severance pay from his factory job and offers the money to the organ dealers, who take the money and one of his kidneys, but then disappear. Three weeks later, Ryu learns from his doctor that a kidney has been found for his sister and that the operation will cost 10,000,000 won, but since the organ dealers stole his money, he will not be able to pay for it.In need of money for the operation and in retaliation for his being fired, Ryu and his girlfriend, Yeong-mi (Doona Bae), a radical anarchist, conspire to kidnap the daughter of the boss who fired him. Instead, he realizes that the kidnapping would immediately put them under police suspicion, and they decide to kidnap Yu-sun (Bo-bae Han), the daughter of the boss's friend, Park Dong-jin (Kang-ho Song), another factory executive. The girl stays with Ryu's sister (thinking that Ryu is merely babysitting for a time), who takes care of her while the distraught Dong-jin arranges to pay her ransom. After Ryu collects the money and returns home, he learns that his sister has discovered his scheme and, unwilling to be involved or burden Ryu further, killed herself. Ryu takes Yu-sun and his sister's body into the countryside to bury her by a riverbed they used to frequent as children. While Ryu mourns, Yu-sun accidentally slips into the river and drowns.Days later, as Dong-jin mourns his daughter and swears revenge at the river bank, Ryu ambushes and murders the organ dealers. Dong-jin, having investigated the identities of the kidnappers, finds Yeong-mi and begins interrogating her. Yeong-mi apologizes for Yu-sun's death but warns him of her membership in a terrorist organization that, knowing Dong-jin's identity, will kill him if she dies. Dong-jin, unfazed by the threats, tortures her to death by electrocuting her. Ryu returns to Yeong-mi's apartment building and discovers the police removing her body on a stretcher. Ryu, consumed with grief, swears vengeance on Dong-jin.Ryu arrives at Dong-jin's residence in an attempt to kill him. He waits for some time, but Dong-Jin does not arrive: he is, in fact, waiting at Ryu's apartment. After Dong-Jin does not arrive, Ryu returns to his apartment. However, Dong-jin had previously set up an electric booby trap on his doorknob, which renders Ryu unconscious. Dong-jin then binds Ryu and returns him to the riverbed where Yu-sun died. After binding Ryu's hands and feet and bringing him chest-high into the water, an emotional Dong-jin acknowledges that although Ryu is a good man, he has no choice; Dong-jin then slashes Ryu's Achilles tendons, resulting in his drowning.Dong-jin drags Ryu back to shore and then drives off to a desolate location to bury the body. Once there, he begins to dig a hole, but soon a group of men arrives. They surround and stab Dong-jin repeatedly, finally attaching a note to his chest identifying themselves as the terrorist group of which Yeong-mi was part. The group leave Dong-jin dying beside his car with the bloody tools and bags he used to chop up, dismember, and package Ryu's body.(From Wikipedia.)
Question: Who's corpse does Dong-jin dismember ? | [
"ryu"
] | task469-8e55944f4f614ee6bf0645fc6f0e69e4 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: To summarize the use of tyrosine kinase inhibitors (TKIs) for treatment of patients with chronic myeloid leukemia (CML) and provide practical information for patient management. Literature was retrieved from PubMed (2000-January 2011), using the search terms chronic myeloid leukemia and tyrosine kinase inhibitor. Abstracts presented at the 2008-2010 annual meetings of the American Society of Hematology and the American Society of Clinical Oncology, reference citations from identified publications, as well as the manufacturers' full prescribing information for cited drugs, also were reviewed. Articles evaluating the efficacy and safety of the TKIs imatinib, nilotinib, and dasatinib were evaluated. Focus was placed on publications supporting management of patients with CML in the chronic phase. Reports presenting clinical trial information of TKIs in development also were included. The discovery of targeted tyrosine kinase inhibition of BCR-ABL kinase dramatically changed the treatment of CML. Imatinib, the first TKI approved for treatment of patients with Philadelphia chromosome--positive CML, demonstrated significant superiority over the previous standard of care: interferon plus cytarabine. The newer, more potent TKIs, nilotinib and dasatinib, have demonstrated improved efficacy over imatinib as first-line therapy and provide an effective option for patients with resistance or intolerance to imatinib. To maximize efficacy of TKI therapy, close patient management, involving frequent monitoring of patient response, is essential. Given the importance of continuing TKI therapy, early recognition and management of adverse events are critical to optimizing outcomes in patients with CML. In addition to the safety profile and considerations of comorbidities, additional factors can affect therapeutic selection, including drug-drug and drug-food interactions. Research investigating new therapies, particularly for patients harboring the T315I mutation-which remains refractory to current TKIs-continues in the quest to improve outcomes in patients with CML.
Question: What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)? | [
"bcr-abl"
] | task469-f197bd934f2440278e59e3c1cbde08e8 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Ant & Dec are an English comedy TV presenting duo, consisting of Anthony McPartlin OBE and Declan Donnelly OBE , from Newcastle upon Tyne, England. Formed after their meeting as actors on CBBC's drama, Byker Grove, the duo have led successful careers as television presenters, with hosting credits including SMTV Live, CD:UK, Friends Like These, Pop Idol, Ant & Dec's Saturday Night Takeaway, I'm a Celebrity...Get Me Out of Here!, PokerFace, Push the Button, Britain's Got Talent, Red or Black?, and Text Santa. Due to a difference in height - Ant being the taller at 5ft 8in , and Dec being two inches shorter at 5ft 6in - the pair identify themselves in the media by adopting the use of the 180-degree rule, with the exception of some early publicity shots. In addition to presenting, the duo are accomplished actors - both had leading roles in the 2006 film Alien Autopsy - operate as television producers - they own their own production company, Mitre Television - have presented the annual Brit Awards in 2001, 2015 and 2016, and are former pop musicians who operated under the aliases of their characters from Byker Grove. In a 2004 poll for the BBC, Ant & Dec were named the eighteenth most influential people in British culture.
Question: Who is the "Ant" in "Ant & Dec"? | [
"anthony mcpartlin obe"
] | task469-4344d1e34551449490b4ff980559654d | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: You are on vacation at the beach. You take your flip-flops off so you can go swimming. The sand is so hot it hurts your feet. You have to run to the water. Now imagine if it were hot enough for the sand to melt. Some places inside Earth are so hot that rock melts. Melted rock inside the Earth is called magma. Magma can be hotter than 1,000C. When magma erupts onto Earths surface, it is known as lava, as Figure 3.17 shows. Minerals form when magma and lava cool. Most water on Earth, like the water in the oceans, contains elements. The elements are mixed evenly through the water. Water plus other substances makes a solution. The particles are so small that they will not come out when you filter the water. But the elements in water can form solid mineral deposits. Fresh water contains a small amount of dissolved elements. Salt water contains a lot more dissolved elements. Water can only hold a certain amount of dissolved substances. When the water evaporates, it leaves behind a solid layer of minerals, as Figure 3.18 shows. At this time, the particles come together to form minerals. These solids sink to the bottom. The amount of mineral formed is the same as the amount dissolved in the water. Seawater is salty enough for minerals to precipitate as solids. Some lakes, such as Mono Lake in California, or Utahs Great Salt Lake, can also precipitate salts. Salt easily precipitates out of water, as does calcite, as Figure 3.19 shows. The limestone towers in the figure are made mostly of the mineral calcite. The calcite was deposited in the salty and alkaline water of Mono Lake, in California. Calcium-rich spring water enters the bottom of the lake. The water bubbles up into the alkaline lake. The Underground water can be heated by magma. The hot water moves through cracks below Earths surface. Hot water can hold more dissolved particles than cold water. The hot, salty solution has chemical reactions with the rocks around it. The water picks up more dissolved particles. As it flows through open spaces in rocks, the water deposits solid minerals. When a mineral fills cracks in rocks, the deposits are called veins. Figure 3.20 shows a white quartz vein. When the minerals are deposited in open spaces, large crystals grow. These rocks are called geodes. Figure 3.20 shows a geode that was formed when amethyst crystals grew in an open space in a rock.
Question: Water in rocks underground can be heated by | [
"magma."
] | task469-e4324b8217724034b021b600d5b4c071 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: A Vampyre Story is a 2008 point-and-click adventure game developed by Autumn Moon Entertainment for Windows, published by Crimson Cow.
Question: Which company developed the videogame A Vampyre Story? | [
"autumn moon entertainment"
] | task469-a41738fcf9d6414ea0c25486ada7a233 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: How quickly is the human population growing? If we look at worldwide human population growth from 10,000 BCE through today, our growth looks like exponential growth. It increased very slowly at first, but later grew faster and faster as the population increased in size ( Figure 1.1). And recently, the human population has increased at a faster pace than ever before. It has taken only 12 years for the worlds population to increase from six billion to seven billion. Considering that in the year 1804, there were just one billion people, and in 1927, there were just two billion people (thats 123 years to increase from 1 to 2 billion), the recent increase in the human population growth rate is characteristic of exponential growth. Does this mean there are unlimited resources? Worldwide human population growth from 10,000 BCE through today. On the other hand, if you look at human population growth in specific countries, you may see a different pattern. On the level of a country, the history of human population growth can be divided into five stages, as described in Table 1.1. Some countries have very high birth rates, in some countries the growth rate has stabilized, and in some countries the growth rate is in decline. Stage 1 2 3 4 5 Description Birth and death rates are high and population growth is stable. This occurred in early human history. Significant drop in death rate, resulting in exponential growth. This occurred in 18th- and 19th-century Eu- rope. Population size continues to grow. Birth rates equal death rates and populations become stable. Total population size may level off. The United Nations and the U.S. Census Bureau predict that by 2050, the Earth will be populated by 9.4 billion people. Other estimates predict 10 to 11 billion. There are two different beliefs about what type of growth the human population will undergo in the future: 1. Neo-Malthusians believe that human population growth cannot continue without destroying the environment, and maybe humans themselves. 2. Cornucopians believe that the Earth can give humans a limitless amount of resources. They also believe that technology can solve problems caused by limited resources, such as lack of food. The Cornucopians believe that a larger population is good for technology and innovation. The 5-stage model above predicts that when all countries are industrialized, the human population will eventually level out. But many scientists and other Neo-Malthusians believe that humans have already gone over the Earths carrying capacity. That means, we may have already reached the maximum population size that can be supported, without destroying our resources and habitat. If this is true, then human overpopulation will lead to a lack of food and other resources. Overpopulation may also lead to increased disease, and/or war. These problems may cause the population of humans to crash. If these issues are not controlled, could the human population go extinct? Which of the above theories makes sense to you? Why?
Question: which is the first stage of human population growth? | [
"birth and death rates are high and population growth is stable."
] | task469-7a74826c82ce4f2aa628fbb543a6c7d6 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Selexipag is a novel, oral, selective prostacyclin (PGI2) receptor agonist in clinical development for the treatment of pulmonary arterial hypertension. Film-coated tablets with strength between 200 and 1,600 g were used. Bioequivalence between 8 x 200 g and a new 1,600 g tablet was evaluated at steady state in healthy male subjects. This was an open-label, 2-treatment, 2-period, crossover, up-titration, phase 1 study. The treatments were selexipag at 1,600 g b.i.d. for 4.5 days either as 8 x 200 g tablets (reference: A) or 1 x 1,600 g tablet (test: B), both preceded by an up-titration phase starting from 400 g b.i.d. doses, in 200-g steps every 4th day. Subjects were randomized 1 : 1 to the A-B or B-A sequence. The pharmacokinetics and tolerability of selexipag and its active metabolite, ACT-333679, were investigated. 80 subjects were enrolled in the study: 65 subjects completed the study according to protocol, and 15 subjects withdrew from the study. The most frequent adverse events (AEs) were headache (86%), myalgia (73%), and jaw pain (73%). There was no difference in nature and overall frequency of AEs between the two treatments. Steady state was attained within 3 days of the selexipag 1,600 g b.i.d. The 90% confidence intervals (CIs) of the geometric mean ratio (B/A) at steady state for AUC and Cmax,ss were within (0.80, 1.25) bioequivalence interval: (0.92, 1.06) and (0.95, 1.14), respectively, for selexipag and (0.95, 1.06) and (0.94, 1.07), respectively, for the active metabolite, ACT-333679. Bioequivalence was demonstrated between 8 x 200 g and 1 x 1,600 g selexipag at steady state.
Question: Selexipag is used for which disease? | [
"pulmonary arterial hypertension"
] | task469-03405d62dd3c4d65b6b533bdb7fbd338 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The new year has begun and some people may be looking to 2015 as the year they get a dog. A furry friend will bring a lot of fun and companionship to your family -- especially for urban residents who always feel lonely living in the fast-paced society. But looking after a pet does require some responsibility from the pet owner if you want your new friend to be healthy and happy in your family. The following is a checklist for people who are considering adopting an animal. Where to find a dog There are hundreds of pet shops in Shanghai, big and small, where you can find puppies at a cost ranging from a few hundred to tens of thousands of yuan. The pet shop will tell you some basic facts about dogs of a specific breed. But don't forget to ask about the vaccination status if you are buying a puppy, which needs three injections with an interval of three to four weeks between shots. Another option is to ask your friends if they know anyone with a dog that has recently had puppies. This option is more reliable than buying a puppy from someone you don't know, especially the street peddlers who might carry animals with diseases. Another highly recommended option is to adopt one from an NGO dedicated to providing shelter and protecting stray animals. This is quite practical if you don't care about the dog's breed. Vaccination As a pet owner, there are some things you must do otherwise you may get into big trouble, and one of these is getting your dog vaccinated. Dogs need regular shots to fight against canine parvovirus , rabies and other diseases or viruses. To ensure the vaccines are not substandard, we strongly recommend you get your furry friend a shot from a qualified _ , which may cost a few hundred yuan each year. Another advantage of using the vet as opposed to getting your dog vaccinated yourself, is that the vet will examine its condition to see whether it is suitable to get a shot now and take immediate action if it has an allergic reaction to the vaccine. Because you are advised not to give your animal a bath for one week following its vaccination, you should clean your animal one or two days before the shot if you don't want your dog to get too dirty. Parasite protection As a pet owner, you need to be prepared to get rid of fleas , heartworm , roundworm , intestinal worms and other parasites from your dog. Dogs need regular flea and tick control and parasite protection, even if it does not show symptoms of being affected by the parasite. An adult dog needs to be fed with a tablet every six months to make sure it does not have any parasite. You also need to take measures every three months to help expel fleas and ticks from your animal. You need to learn the signs of a flea bite: they may immediately cause a dog to feel extremely itchy. Within 30 minutes of a bite, they may develop a red bump. Secondary infections caused by scratching are also common. Dog training No dog is born with good manners. Pooping on the carpet, leaping enthusiastically onto guests, pulling so hard that it practically yanks your arm out of the socket when on walks -- that's all perfectly acceptable in the canine world. It's up to you to teach your dog to behave the way humans want it to. Despite the adage(;) about old dogs and new tricks, there are no age limits to teaching dogs. And whether you've got a brand-new puppy or an older dog, the first step is the same: learn how to be a good teacher. Every dog is different and will respond better to a slightly different training style, but these general guidelines apply: stay consistent and patient, and reward your dog for getting it right.
Question: According to the article, how many aspects should a pet owner pay attention to? | [
"four"
] | task469-105a1bcf20344cfdadb9022b681f3ec0 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The war had three phases. Initially it was a localized feud between supporters of Gebhard and those of the Catholic core of the Cathedral Chapter. With the election of Ernst of Bavaria as a competing archbishop, what had been a local conflict expanded in scale: Ernst's election guaranteed the military, diplomatic, and financial interest of the Wittelsbach family in the Electorate of Cologne's local affairs. After the deaths of Louis VI, Elector Palatine in 1583and William the Silent in 1584, the conflict shifted gears again, as the two evenly matched combatants sought outside assistance to break the stalemate. Finally, the intervention of Alexander Farnese, Duke of Parma, who had at his command the Spanish Army of Flanders, threw the balance of power in favor of the Catholic side. By 1588, Spanish forces had pushed Gebhard from the Electorate. In 1588 he took refuge in Strassburg, and the remaining Protestant strongholds of the Electorate fell to Parma's forces in 1589.
Question: After Louis VI, Elector Palatine, and Williant the Silent died, what set into motion the third phase of the war? | [
"the intervention of alexander farnese"
] | task469-134c12b0f02b458bbe66e626911eede3 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Krechek or krecek or sambal goreng krechek is a traditional Javanese cattle skin spicy stew dish from Yogyakarta and Central Java, Indonesia.
Question: The country of origin for Krechek is what? | [
"indonesia"
] | task469-73a720c6dd0a477db8e4216db4472fbd | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Perhaps you have heard a lot about the Internet, but what is it, do you know? The Internet is a network. It uses the telephone to join millions of computers together around the world. Maybe that doesn't sound very interesting. But when you're joined to the Internet, there are lots and lots of things you can do. You can send E-mails to your friends, and they can get them in a few seconds. You can also do with all kinds of information on the World Wide Web (www). There are many different kinds of computers now. They all can be joined to the Internet. Most of them are small machines sitting on people's desks at home, but there are still many others in schools, offices or large companies. These computers are owned by people and companies, but no one really owns the Internet itself. There are lots of places for you to go into the Internet. For example, your school may have the Internet. You can use it during lessons or free time. Libraries often have computers joined to the Internet. You are welcome to use it at any time. Thanks to the Internet, the world is becoming smaller and smaller. It is possible for you to work at home with a computer in front, getting and sending the information you need. You can buy or sell whatever you want on the Internet. But do you know 98% of the information on the Internet is in English? So what will English be like tomorrow?
Question: What is the passage mainly about? | [
"internet."
] | task469-6e8b773c8d5346a18e95dc5bf48af1fe | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Britons spend as much as nearly five hours a week keeping their homes clean, a survey found. Kitchens are cleaned most often, while doing the oven and windows are the least popular jobs. In total, they spend just over PS1 billion a year on products to keep the dirt at bay -- almost PS40 per household. Market analyst Mintel found a clear division of labour. While the average Briton spends 4 hours, 40 minutes cleaning their home each week, men spend just 3 hours, 53 minutes compared to 5 hours, 25 minutes for women. And while seven in ten women say they do most of the cleaning, this falls to four in ten for men. Confirming many parents' feelings, only one in five adult children and over living at their parents' home helps with cleaning chores, with children under 18 doing even less. Last year, the household cleaning market was worth PS1.06 billion, which equates to annual spending of PS39.89 per household. Those looking for the cleanest homes in the country should head to Scotland, where people spend an average of five fours, 6 minutes, which is closely followed by East and West Midlands at five hours, 1 minute. In comparison, the least number of hours spent in cleaning is spent in the southeast/East Anglia at four hours, 18 minutes. The southwest and Wales stand at four hours, 46 minutes, the northwest four hours, 44 minutes, and Yorkshire and the Humber four hours, 21 minutes. According to Richard Caines, Mintel's senior household care analyst, men still lag women in the household cleaning stakes and spend on average an hour and a half less time cleaning their home, suggesting an opportunity for a campaign to encourage more cleaning by men to helpredressthis imbalance. The number of households that need cleaning is continuing to grow, but pressure on time from increasingly busy lives limits the number of hours people are willing or able to spend cleaning their homes. This means the market will see an increasing focus on easy-to-use, but effective hard surface cleaners and cleaning equipment. Such products can help encourage more cleaning to be done in less time, but as well as focusing on more convenient products, cleaning brands can also inject an element of fun into campaigns through encouraging a more shared approach that involves the whole family. This will also help to address the gender imbalance and get older children to make more of a contribution to cleaning.
Question: In which area do people spend the most time cleaning their home each week? | [
"scotland."
] | task469-008318fd19144b2292525cac8162a0a1 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: In Hawaiian mythology, Namaka (or Na-maka-o-Kahai, the eyes of Kahai) appears as a sea goddess or a water spirit in the Pele cycle.
Question: Who is Namaka's sister? | [
"pele"
] | task469-4113b370b4be4ed39cf1d89d5b59c256 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: An electromagnetic wave is a wave that consists of vibrating electric and magnetic fields. A familiar example will help you understand the fields that make up an electromagnetic wave. Think about a common bar magnet. It exerts magnetic force in an area surrounding it, called the magnetic field. You can see the magnetic field of a bar magnet in Figure 21.1. Because of this force field, a magnet can exert force on objects without touching them. They just have to be in its magnetic field. An electric field is similar to a magnetic field (see Figure 21.1). An electric field is an area of electrical force surrounding a charged particle. Like a magnetic field, an electric field can exert force on objects over a distance without actually touching them. An electromagnetic wave begins when an electrically charged particle vibrates. This is illustrated in Figure 21.2. When a charged particle vibrates, it causes the electric field surrounding it to vibrate as well. A vibrating electric field, in turn, creates a vibrating magnetic field (you can learn how this happens in the chapter "Electromagnetism"). The two types of vibrating fields combine to create an electromagnetic wave. You can see an animation of an electromagnetic wave at this URL: (1:31). MEDIA Click image to the left or use the URL below. URL: As you can see in Figure 21.2, the electric and magnetic fields that make up an electromagnetic wave occur are at right angles to each other. Both fields are also at right angles to the direction that the wave travels. Therefore, an electromagnetic wave is a transverse wave. Unlike a mechanical transverse wave, which requires a medium, an electromagnetic transverse wave can travel through space without a medium. Waves traveling through a medium lose some energy to the medium. However, when an electromagnetic wave travels through space, no energy is lost, so the wave doesnt get weaker as it travels. However, the energy is "diluted" as it spreads out over an ever-larger area as it travels away from the source. This is similar to the way a sound wave spreads out and becomes less intense farther from the sound source. Electromagnetic waves can travel through matter as well as across space. When they strike matter, they interact with it in the same ways that mechanical waves interact with matter. They may reflect (bounce back), refract (bend when traveling through different materials), or diffract (bend around objects). They may also be converted to other forms of energy. Microwaves are a familiar example. They are a type of electromagnetic wave that you can read about later on in this chapter, in the lesson "The Electromagnetic Spectrum." When microwaves strike food in a microwave oven, they are converted to thermal energy, which heats the food. Electromagnetic radiation behaves like waves of energy most of the time, but sometimes it behaves like particles. As evidence accumulated for this dual nature of electromagnetic radiation, the famous physicist Albert Einstein developed a new theory about electromagnetic radiation, called the wave-particle theory. This theory explains how electromagnetic radiation can behave as both a wave and a particle. In brief, when an electron returns to a lower energy level, it is thought to give off a tiny "packet" of energy called a photon (see Figure 21.3). The amount of energy in a photon may vary. It depends on the frequency of electromagnetic radiation. The higher the frequency is, the more energy a photon has. The most important source of electromagnetic radiation on Earth is the sun. Electromagnetic waves travel from the sun to Earth across space and provide virtually all the energy that supports life on our planet. Many other sources of electromagnetic waves that people use depend on technology. Radio waves, microwaves, and X rays are examples. We use these electromagnetic waves for communications, cooking, medicine, and many other purposes. Youll learn about all these types of electromagnetic waves in this chapters lesson on "The Electromagnetic Spectrum."
Question: wave in which vibrations occur at right angles to the direction the wave travels | [
"transverse wave"
] | task469-9ae2cefde76a4cdd83f6b92915036146 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Acceleration is a measure of the change in velocity of a moving object. It measures the rate at which velocity changes. Velocity, in turn, is a measure of the speed and direction of motion, so a change in velocity may reflect a change in speed, a change in direction, or both. Both velocity and acceleration are vectors. A vector is any measurement that has both size and direction. People commonly think of acceleration as in increase in speed, but a decrease in speed is also acceleration. In this case, acceleration is negative and called deceleration. A change in direction without a change in speed is acceleration as well. Q: Can you think of an example of acceleration that doesnt involve a change in speed? A: Driving at a constant speed around a bend in a road is one example. Use your imagination to think of others. You can see several examples of acceleration in the pictures from the Figure 1.1. In each example, velocity is changing but in different ways. For example, direction may be changing but not speed, or vice versa. Figure out what is moving and how its moving in each of the photos. Q: Describe how velocity is changing in each of the motions you identified from the Figure 1.1. A: You should describe how both direction and speed are changing. For example, the boy on the carousel is moving up and down and around in a circle, so his direction is constantly changing, but his speed changes only at the beginning and end of the ride. The skydiver is falling straight down toward the ground so her direction isnt changing, but her speed keeps increasing as she falls until she opens her parachute. If you are accelerating, you may be able to feel the change in velocity. This is true whether the change is in speed, direction, or both. You often feel acceleration when you ride in a car. As the car speeds up, you feel as though you are being pressed against the seat. When the car slows down, you feel like you are being pushed forward, especially if the change in speed is sudden. If the car changes direction and turns right, you feel as though you are being pushed to the left. With a left turn, you feel a push to the right. The next time you ride in a car, notice how it feels as the car accelerates in each of these ways.
Question: acceleration always refers to a(n) | [
"change in velocity."
] | task469-48df586f0f0f4e329c663cc63f989b13 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Astrocytomas are the leading cause of brain cancer in humans. Because these tumours are highly infiltrative, current treatments that rely on targeting the tumour mass are often ineffective. A mouse model for astrocytoma would be a powerful tool for dissecting tumour progression and testing therapeutics. Mouse models of astrocytoma have been designed to express oncogenic proteins in astrocytes, but have had limited success due to low tumour penetrance or limited tumour progression. We present here a mouse model of astrocytomas involving mutation of two tumour-suppressor genes, Nf1 and Trp53. Humans with mutations in NF1 develop neurofibromatosis type I (NF1) and have increased risk of optic gliomas, astrocytomas and glioblastomas. The TP53 tumour suppressor is often mutated in a subset of astrocytomas that develop at a young age and progress slowly to glioblastoma (termed secondary glioblastomas, in contrast to primary glioblastomas that develop rapidly de novo). This mouse model shows a range of astrocytoma stages, from low-grade astrocytoma to glioblastoma multiforme, and may accurately model human secondary glioblastoma involving TP53 loss. This is the first reported mouse model of astrocytoma initiated by loss of tumour suppressors, rather than overexpression of transgenic oncogenes.
Question: Which is the gene mutated in type 1 neurofibromatosis? | [
"nf1"
] | task469-c44fbf370595406a8638c5b2ba6a53bf | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: When a new moon passes directly between the Earth and the Sun, it causes a solar eclipse (Figure 24.20). The Moon casts a shadow on the Earth and blocks our view of the Sun. This happens only all three are lined up and in the same plane. This plane is called the ecliptic. The ecliptic is the plane of Earths orbit around the Sun. The Moons shadow has two distinct parts. The umbra is the inner, cone-shaped part of the shadow. It is the part in which all of the light has been blocked. The penumbra is the outer part of Moons shadow. It is where the light is only partially blocked. When the Moons shadow completely blocks the Sun, it is a total solar eclipse (Figure 24.21). If only part of the Sun is out of view, it is a partial solar eclipse. Solar eclipses are rare events. They usually only last a few minutes. That is because the Moons shadow only covers a very small area on Earth and Earth is turning very rapidly. Solar eclipses are amazing to experience. It appears like night only strange. Birds may sing as they do at dusk. Stars become visible in the sky and it gets colder outside. Unlike at night, the Sun is out. So during a solar eclipse, its easy to see the Suns corona and solar prominences. This NASA page will inform you on when solar eclipses are expected: [Link] Sometimes a full moon moves through Earths shadow. This is a lunar eclipse (Figure 24.22). During a total lunar eclipse, the Moon travels completely in Earths umbra. During a partial lunar eclipse, only a portion of the Moon enters Earths umbra. When the Moon passes through Earths penumbra, it is a penumbral eclipse. Since Earths shadow is large, a lunar eclipse lasts for hours. Anyone with a view of the Moon can see a lunar eclipse. Partial lunar eclipses occur at least twice a year, but total lunar eclipses are less common. The Moon glows with a dull red coloring during a total lunar eclipse. The Moon does not produce any light of its own. It only reflects light from the Sun. As the Moon moves around the Earth, we see different parts of the Moon lit up by the Sun. This causes the phases of the Moon. As the Moon revolves around Earth, it changes from fully lit to completely dark and back again. A full moon occurs when the whole side facing Earth is lit. This happens when Earth is between the Moon and the Sun. About one week later, the Moon enters the quarter-moon phase. Only half of the Moons lit surface is visible from Earth, so it appears as a half circle. When the Moon moves between Earth and the Sun, the side facing Earth is completely dark. This is called the new moon phase. Sometimes you can just barely make out the outline of the new moon in the sky. This is because some sunlight reflects off the Earth and hits the Moon. Before and after the quarter-moon phases are the gibbous and crescent phases. During the crescent moon phase, the Moon is less than half lit. It is seen as only a sliver or crescent shape. During the gibbous moon phase, the Moon is more than half lit. It is not full. The Moon undergoes a complete cycle of phases about every 29.5 days.
Question: phase of the moon in which half of the side facing Earth is lit | [
"quarter moon",
"quarter-moon"
] | task469-d6b514300d0b4e75888b3fca7aa639af | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Conquest of Melilla occurred in September 1497, when a fleet sent by the Duke of Medina Sidonia seized the north African city of Melilla., as continuation of Reconquest of Mauritania Tingitana During the 15th century the mediterranean cities of the Sultanate of Fez fell in decadence in opposition to cities located in the Atlantic facade, which concentrated most of the economic activity. By the end of the 15th century, the port of Melilla, that had been often disputed between the rulers of Fez and Tlemcen, was nearly abandoned. Plans for the conquest occurred as soon as the Fall of Granada in 1492. Spanish captains Lezcano and Lorenzo Zafra visited the coast of Northern Africa to identify possible locations for the Spanish to overtake, and Melilla was identified as a prime candidate. Melilla was, however, in the Portuguese zone of influence under the terms of the 1479 Treaty of Alcacovaz. At Tordesillas in 1494, King John II of Portugal, the Portuguese ruler agreed to make an exception and permitted the Spanish to attempt the conquest of Melilla. The duke sent Pedro Estopinan who conquered the city virtually without a fight in 1497, as internal conflicts had depleted it of troops, and its defenses were weakened. The Wattasid ruler Muhammad al-Shaykh sent a detachment of cavalrymen to retake control of the city, but they were repulsed by the guns of the Spanish ships.
Question: Which event happened first, Treaty of Alcacovaz or Fall of Granada? | [
"fall of granada"
] | task469-59628bd8f6cb434d9ce8aff07b286fee | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Estadio Palma Travassos is owned by Comercial Futebol Clube (Ribeirao Preto).
Question: What team uses Estadio Palma Travassos? | [
"comercial futebol clube"
] | task469-0e402e99269c4f2eafad6b7d9538a085 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Carbon is a nonmetal in group 14 of the periodic table. Like other group 14 compounds, carbon has four valence electrons. Valence electrons are the electrons in the outer energy level of an atom that are involved in chemical bonds. The valence electrons of carbon are shown in Figure 9.1. Because it has four valence electrons, carbon needs four more electrons to fill its outer energy level. It can achieve this by forming four covalent bonds. Covalent bonds are chemical bonds that form between nonmetals. In a covalent bond, two atoms share a pair of electrons. By forming four covalent bonds, carbon shares four pairs of electrons, thus filling its outer energy level. A carbon atom can form bonds with other carbon atoms or with the atoms of other elements. Carbon often forms bonds with hydrogen. You can see an example in Figure 9.2. The compound represented in the figure is methane (CH4 ). The carbon atom in a methane molecule forms bonds with four hydrogen atoms. The diagram on the left shows all the shared electrons. The diagram on the right represents each pair of shared electrons with a dash (). This type of diagram is called a structural formula. Carbon can form single, double, or even triple bonds with other carbon atoms. In a single bond, two carbon atoms share one pair of electrons. In a double bond, they share two pairs of electrons, and in a triple bond they share three pairs of electrons. Examples of compounds with these types of bonds are shown in Figure 9.3. Because of carbons ability to form so many covalent bonds, it often forms polymers. A polymer is a large molecule that consists of many smaller molecules joined together by covalent bonds. The smaller molecules are called monomers. (The prefix mono means "one," and the prefix poly means "many.") Polymers may consist of just one type of monomer or of more than one type. Polymers are a little like the strings of beads in Figure 9.4. What do the individual beads represent? Many polymers occur naturally. You will read about natural polymers in this chapters "Hydrocarbons" and "Carbon and Living Things" lessons. Other polymers are synthetic. This means that they are produced in labs or factories. Synthetic polymers are created in synthesis reactions in which monomers bond together to form much larger compounds. Plastics are examples of synthetic polymers. The plastic items in Figure 9.5 are all made of polythene (also called polyethylene). It consists of repeating monomers of ethene (C2 H4 ). To learn more about polymers and how they form, go to this URL: (2:13). Exploratorium Staff Scientist Julie Yu changes and manipulates the physical and chemical properties of plastic bottles by exposing them to heat. This is how plastic bags and bottles can be recycled and used over and over again. For more information on properties of plastic, see [Link] MEDIA Click image to the left or use the URL below. URL: Pure carbon can exist in different forms, depending on how its atoms are arranged. The forms include diamond, graphite, and fullerenes. All three forms exist as crystals, but they have different structures. Their different structures, in turn, give them different properties. You can learn more about them in Table 9.1. atoms affect the properties of the substances formed? Structure Diamond crystal Description Diamond Diamond is a form of carbon in which each carbon atom is bonded to four other carbon atoms. This forms a strong, rigid, three- dimensional structure. Diamond is the hardest natural substance. It is used for cutting and grinding tools as well as for rings and other pieces of jewelry. Graphite Graphite is a form of carbon in which carbon atoms are arranged in layers. Bonds are strong between carbon atoms within each layer but relatively weak between atoms in different layers. The weak bonds between layers allow the layers to slide over one another. This makes graphite relatively soft and slippery. It is used as a lubricant. It also makes up the "lead" in pencils. Fullerene A fullerene (also called a bucky- ball) is a form of carbon in which carbon atoms are arranged in
Question: form of carbon in which carbon atoms are arranged in hollow spheres | [
"fullerene"
] | task469-00a74529b7d54bd8ab60e617399dcd93 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: They Met in Argentina is a 1941 American film, directed by Leslie Goodwins and Jack Hively for RKO Pictures, Hively had to come in and finish the picture after Goodwins was hospitalized for pneumonia.
Question: What was the name of the director for They Met in Argentina? | [
"leslie goodwins"
] | task469-cdae49d56c604812bcb92ba9a9d43266 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: We need natural resources for just about everything we do. We need them for food and clothing, for building materials and energy. We even need them to have fun. Table 20.1 gives examples of how we use natural resources. Can you think of other ways we use natural resources? Use Vehicles Resources Rubber for tires from rubber trees Steel frames and other metal parts from minerals such as iron Example iron ore Use Electronics Resources Plastic cases from petroleum prod- ucts Glass screens from minerals such as lead Example lead ore Homes Nails from minerals such as iron Timber from trees spruce timber Jewelry Gemstones such as diamonds Minerals such as silver silver ore Food Sunlight, water, and soil Minerals such as phosphorus corn seeds in soil Clothing Wool from sheep Cotton from cotton plants cotton plants Recreation Water for boating and swimming Forests for hiking and camping pine forest Some natural resources are renewable. Others are not. It depends in part on how we use them. Renewable resources can be renewed as they are used. An example is timber, which comes from trees. New trees can be planted to replace those that are cut down. Sunlight is a renewable resource. It seems we will never run out of that! Just because a resource is renewable, it doesnt mean we should use it carelessly. If we arent careful, we can pollute resources. Then they may no longer be fit for use. Water is one example. If we pollute a water source it may not be usable for drinking, bathing or any other type of use. We can also overuse resources that should be renewable. In this case the resources may not be able to recover. For example, fish are renewable resources. Thats because they can reproduce and make more fish. But water pollution and overfishing can cause them to die out if their population becomes too low. Figure 20.1 shows another example. Some resources cant be renewed. At least, they cant be renewed fast enough to keep up with use. Fossil fuels are examples. It takes millions of years for them to form. We are using them up much more quickly. Elements that are used to produce nuclear power are other examples. They include uranium. This element is already rare. Sooner or later, it will run out. Supplies of non-renewable resources are shrinking. This makes them harder to get. Oil is a good example. Oil reserves beneath land are running out. So oil companies have started to drill for oil far out in the ocean. This costs more money. Its also more dangerous. Figure 20.2 shows an oil rig that exploded in 2010. The explosion killed 11 people. Millions of barrels of oil spilled into the water. It took months to plug the leak. Rich nations use more natural resources than poor nations. In fact, the richest 20 percent of people use 85 percent of the worlds resources. What about the poorest 20 percent of people? They use only 1 percent of the worlds resources. You can see this unequal distribution of oil resources in Figure 20.3. Imagine a world in which everybody had equal access to resources. Some people would have fewer resources than they do now. But many people would have more. In the real world, the difference between rich and poor just keeps growing. Every 20 minutes, the human population adds 3,500 more people. More people need more resources. For example, we now use five times more fossil fuels than we did in 1970. The human population is expected to increase for at least 40 years. What will happen to resource use? How can we protect Earths natural resources? One answer is conservation. This means saving resources. We need to save resources so some will be left for the future. We also need to protect resources from pollution and overuse. When we conserve resources, we also cut down on the trash we produce. Americans throw out 340 million tons of trash each year. We throw out 2.5 million plastic bottles alone every hour! Most of what we throw out ends up in landfills. You can see a landfill in Figure 20.4. In a landfill, all those plastic bottles take hundreds of
Question: example of a renewable resource | [
"water"
] | task469-0c22a1221e16478da8d501a0e8977ef2 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Piacenza Calcio 1919 play their home matches at the 21,668 capacity, Stadio Leonardo Garilli, located in the city of Piacenza.
Question: What was the name of Piacenza Calcio 1919's home stadium? | [
"stadio leonardo garilli"
] | task469-0ef4c17a0d6a43f0b81ad6ff8d17eb1f | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The movie begins in the year 1967 with a pregnant woman being admitted to a hospital, bleeding from the neck. Paramedics think she was attacked by some type of animal. Doctors perform an emergency C-Section, and her baby (a boy) is born alive just as she dies.Thirty years later a young man named Dennis (Kenny Johnson) is riding in a car with an attractive redhead named Racquel (Traci Lords) heading to an underground nightclub (located, oddly, in a slaughterhouse) somewhere in Los Angeles. After addressing the doorman in Russian, Racquel brings the young man into the club. The man is confused and trying to understand the rules of the club. Some of the regulars indifferently push him aside. Saying he needs a drink, the sprinkler suddenly system activates, raining blood down on everyone inside. It is then that he (and the audience) realizes that everyone in the club is a vampire.Dennis desperately tries to get away and winds up at the feet of a menacing figure in a black-leather trenchcoat. The vampires look on this figure with awe, mumbling the words: "it's the Daywalker!" This is our first look at Blade (Wesley Snipes), the vampire killer.Blade pulls out a shotgun and opens fire on the vampires, who instantly burn to ashes when killed. When the gun is knocked out of his hands by Racquel, Blade uses a set of silver stakes to kill Racquel and more vampires, including the disk jockey. Soon all the vamps are either dead or have fled except for one; a heavyset vamp named Quinn (Donal Logue), whom Blade has apparently run into before. Blade pins Quinn to the wall, and then sets him on fire before confronting the last member in the club (the human man from the beginning). Finding no vampire bite marks on Dennis, Blade lets him live and makes his escape as the police arrive.Quinn is extinguished and taken to the local hospital. A morgue technician examines his blood and shows the results to Dr. Karen Jenson (N'Bushe Wright), who finds a number of irregularities, including abnormally developed jaw muscles. As they are discussing the test results, Quinn springs back to life and bites both doctors. Before he can finish Dr. Jenson, Blade shows up and saves her, cutting off one of Quinn's arms.Blade brings Karen to his hideout and asks for help from his mentor, an elderly man named named Whistler (Kris Kristofferson). Whistler injects Dr. Jenson with a solution of garlic essence and silver nitrate and remarks that she has a 50/50 chance of recovering.Meanwhile, a group of vampires are discussing Blade's latest attack on their members. Apparently this club (and to an extent, Quinn) is the property of a vampire named Deacon Frost (Stephen Dorff). Frost wants the vampires to outright rule the humans and use them as a food source while the others (particularly an older vampire named Dragonetti) prefer to maintain a peaceful co-existance. Dragonetti (Udo Kier) in particular does not like Frost because Frost is not a "pure-blood" (ie: was not born a vampire, merely became one through the bite of another). Frost is also arrogant and his & the actions of his followers draw unnecessary attention to the vampire underworld.The next morning, Jenson awakens and sees Whistler injecting Blade with some type of serum. She tries to run away but Whistler confronts her and tells her that he and Blade are hunting vampires. Karen of course is skeptical, but Whistler goes on to talk about what they use to hunt- explaining that vampires are severely allergic to silver & garlic while also being vulnerable to sunlight (ultraviolet rays in particular). Whistler fuels up Blade's car and gives him a new UV flashlight to use when hunting that night. Whistler also gives Karen a type of "vampire mace" (garlic & silver nitrate in a liquid form).Blade drops Karen off at her apartment and she tries to pack up and get out of town. A police officer, identifying himself as Officer Krieger (Kevin Patrick Walls), arrives and questions her about the events
Question: Who owned the rave club? | [
"rave club owned by the vampire deacon frost.",
"deacon frost"
] | task469-39f7b53abe744e0c88ba3ae07f93e869 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Five teens from Sarasota, Florida, are making music from garbage. The Garbage-Men band's instruments are made from recycled objects. The guitars are boxes. A horn is made from pipes. The keyboard is formed from old bottles. The band started about two years ago. Jack Berry decided to make a playable, homemade guitar. After some trial-and-error, he ended up building it from a cereal box, a yardstick and toothpicks. After Jack showed his creation to his friend Ollie Gray, Ollie had the idea to form a band using other homemade instruments as a way to promote recycling. "We want to show people there is more to recycling than throwing things away in the bin ," Jack, 16, said, "You can actually reuse materials." Ollie, 15, plays drums made from trash cans. Evan Tucker, 15 (bass guitar); Harrison Paparatto, 15 (horns and violin); and Austin Siegel, 15, (keyboard), round out the band. The Garbage-Men plays at local events around Sarasota, including festivals, farmer's markets and community fundraisers. Typically, the teens will set up on the street and perform popular songs from the 1960s, including classic Beatles tunes and people's favorite "Wipe Out," by The Surfaris. In between sets, they talk about recycling the offer tips for how to help the environment. while they perform, Jack's little brother Trent, 11, gives out flyers about recycling and helps sell the band's CD and other merchandise. The band donates the money from sales to charity. They have raised more than $2,500 for Heifer International. The organization gives farm animals, seeds and agricultural training to people in poor countries to help end poverty and hunger. The band--all tenth graders--tries to play a gig for America's Got Talent. The teens hope to eventually take their show on the road by touring in other states. "Music is a really good way to get a good message across to people because it's really accessible," Jack says. Their instruments may be garbage, but their message isn't.
Question: What's the purpose of the garbage-Men band? | [
"to promote recycling."
] | task469-bdc0989290324290acd6f448367d6fa6 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: People all over the world today are beginning to hear and learn more and more about the problem of pollution.Pollution is caused either by man's release of completely new artificial substances into the environment,or by releasing greatly increased amounts of a natural substance,such as oil from oil tankers into the sea. The whole industrial process which makes many of the goods and machines we need and use in our daily lives,is bound to create a number of waste products which upset the environmental balance,or the ecological balance as is also known.Many of these waste products can be prevented or disposed of.But while more and more new and complex goods are produced,there will be new,dangerous waste to be disposed of,for example,the waste products from nuclear power stations.Many people,therefore,see pollution as only part of a larger and more complex problem,that is,the whole process of industrial production and consumption of goods.Others again see the problem mainly in connection with agriculture,where new methods are helping farmers grow more and more on their land to feed our ever-increasing population.However,the land itself is gradually becoming worn out as it is being used,in some cases,too heavily,and artificial fertilizers can not restore the balance. Whatever its underlying reasons are,there is no doubt that much of the pollution caused could be controlled if only companies,individuals and governments would make more efforts.In the home there is an obvious need to control litter and waste.Food comes wrapped up three or four times in packages that all have to be disposed of;drinks are increasingly sold in bottles or tins which can not be reused.This not only causes a litter problem,but also is a great waste of resources,in terms of glass,metals and paper.Advertising has helped this process by persuading many of us not only to buy things we neither want nor need,but also to throw away much of what we do buy.Pollution and waste combine to be a problem everyone can help to solve by cutting out unnecessary buying,excessive consumption and careless disposal of the products we use in our daily lives.
Question: Many people see pollution as only part of . | [
"the whole process of industrial production and consumption of goods"
] | task469-1eda9a0cbb564e1f811c287299e479e1 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Saturday, October 8, 120 miles northeast of Blainsworth, Nebraska; 1:16 p.m.Bob Irisin, a metrologist for the Kansas City weather bureau, is riding in his Bronco truck when he stops and radios to his friend Stan in Kansas City, that he is witnessing a sudden change in weather patterns in the area. Then a tornado suddenly touches down near a farm where Bob sees a family of a man, woman and their little girl standing in front of the house, unaware of the tornado approaching behind them. Bob drives as near as he can go and manages to yell out a warning to the family seconds before they see the twister coming. The family runs into their storm shelter just in time before the twister destroys their house. Bob drives away from harms way just in time.Meanwhile, in Blainsworth, there is the annual fall Bike-a-thon race for the high school kids. 13-year-old Dan Hatch gets a flat tire and doesnt come in at all. Dans stern father, Jack, is arguing with a banker who's asking to foreclose on his hardware shop since a new mall has opened in the nearby town. Jack refuses to sell the shop at any price. Dan walks his bike into the town square where his best friend, Arthur, talks with him about getting "crashed and burned" during the race. Jack walks over and becomes hard on Dan for not finishing the race like a man should. Dan yells at his father for being so demanding and that he can't expect anything from anyone. Dan's mother, Laura, with her new baby Ryan and her friend Jenny, walk by and never less tell him he did okay anyway. Just then, Dan is called to the square podium for he is has been chosen by a lottery to be the winner of a new Schwinn Voyager bicycle, much to his father and mother's delight.75 miles northeast of Blainsworth; 3:37 p.m. Bob sits in his Bronco truck and radios in of rogue weather patterns, while observing another tornado rip through a nearby trailer park. Bob tells Stan that the front is moving south instead of north and the atmospheric activity is the most bizarre he has ever seen. Bob decides to travel to Blainsworth to see if anything will happen.Outside of Blainsworth, Dan and Arthur sit in the woods looking up at the clear sky. Dan tell Arthur about his fathers demanding which is a driving force that he cant stand. Then Arthur's two younger sisters, Stacey and Ronnie Vae, appear and want Arthur to come home since their parents are out of town for the weekend. Arthur and Dan watch as clouds begin to roll in and they decide to get indoors. At Arthurs house, the boys play a game of pool, in which Dan forgets he's suppose to take his grandmother's dog for a walk.Six miles northeast of Blainsworth 4:30 p.m.; Dan arrives at his grandmother Goldie's house where his father is already there taking her dog to the vet, for it has a bad leg. Jack yells at Dan for not being responsible for anything, and Dan rides on his new bike home.Arthur arrives at the Hatch house, were Laura is getting ready to leave for work for the evening. Jenny arrives at the house to pick Laura up, were they talk about Jack being so domineering on Dan for he doesn't want Dan to end up a loser like him.Nightfall. Arthur and Dan play with musical instruments, while checking every few minutes if baby Ryan in the next room is all right. Jack then arrives and tells Dan and Arthur to bring their bicycles in for its raining. Going out, they find that its raining hard and the winds are picking up speed. Arthur tells Dan that since hes originally from Los Angeles, he enjoys the rain, while Dan sees little amusement in it, for he tells Arthur that rain and hailstorms can get bad.At the local diner in town, Laura is waitressing when Bob walks in asking for some coffee. Bob overhears a farmer named Gus talk about the storm and of tornados reported in the area. Bob tells Gus that most people killed by tornados
Question: Where does Bob decide to go? | [
"blainsworth"
] | task469-e9736406c88a4ef19b76878780e27377 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Friction is a force that opposes motion between two surfaces that are touching. Friction can work for or against us. For example, putting sand on an icy sidewalk increases friction so you are less likely to slip. On the other hand, too much friction between moving parts in a car engine can cause the parts to wear out. Other examples of friction are illustrated in Figure 13.7. You can see an animation showing how friction opposes motion at this URL: [Link] Friction occurs because no surface is perfectly smooth. Even surfaces that look smooth to the unaided eye appear rough or bumpy when viewed under a microscope. Look at the metal surfaces in Figure 13.8. The metal foil is so smooth that it is shiny. However, when highly magnified, the surface of metal appears to be very bumpy. All those mountains and valleys catch and grab the mountains and valleys of any other surface that contacts the metal. This creates friction. Rougher surfaces have more friction between them than smoother surfaces. Thats why we put sand on icy sidewalks and roads. The blades of skates are much smoother than the soles of shoes. Thats why you cant slide as far across ice with shoes as you can with skates (see Figure 13.9). The rougher surface of shoes causes more friction and slows you down. Heavier objects also have more friction because they press together with greater force. Did you ever try to push boxes or furniture across the floor? Its harder to overcome friction between heavier objects and the floor than it is between lighter objects and the floor. You know that friction produces heat. Thats why rubbing your hands together makes them warmer. But do you know why the rubbing produces heat? Friction causes the molecules on rubbing surfaces to move faster, so they have more heat energy. Heat from friction can be useful. It not only warms your hands. It also lets you light a match (see Figure 13.10). On the other hand, heat from friction can be a problem inside a car engine. It can cause the car to overheat. To reduce friction, oil is added to the engine. Oil coats the surfaces of moving parts and makes them slippery so there is less friction. There are different ways you could move heavy boxes. You could pick them up and carry them. You could slide them across the floor. Or you could put them on a dolly like the one in Figure 13.11 and roll them across the floor. This example illustrates three types of friction: static friction, sliding friction, and rolling friction. Another type of friction is fluid friction. All four types of friction are described below. In each type, friction works opposite the direction of the force applied to a move an object. You can see a video demonstration of the different types of friction at this URL: (1:07). Static friction acts on objects when they are resting on a surface. For example, if you are walking on a sidewalk, there is static friction between your shoes and the concrete each time you put down your foot (see Figure 13.12). Without this static friction, your feet would slip out from under you, making it difficult to walk. Static friction also allows you to sit in a chair without sliding to the floor. Can you think of other examples of static friction? Sliding friction is friction that acts on objects when they are sliding over a surface. Sliding friction is weaker than static friction. Thats why its easier to slide a piece of furniture over the floor after you start it moving than it is to get it moving in the first place. Sliding friction can be useful. For example, you use sliding friction when you write with a pencil and when you put on your bikes brakes. Rolling friction is friction that acts on objects when they are rolling over a surface. Rolling friction is much weaker than sliding friction or static friction. This explains why it is much easier to move boxes on a wheeled dolly than by carrying or sliding them. It also explains why most forms of ground transportation use wheels, including cars, 4-wheelers, bicycles, roller
Question: type of friction between an object and a gas or liquid | [
"fluid friction"
] | task469-4a059cd5e1d3439e89f6f8866909977c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Le tombeau de Couperin is a suite for solo piano by Maurice Ravel, composed between 1914 and 1917, in six movements based on those of a traditional Baroque suite.
Question: What musical instrument was Le tombeau de Couperin created for? | [
"piano"
] | task469-40b433a343fb483fb1727d9f11a70967 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: No doubt you already have a good idea of what temperature is. You might define it as how hot or cold something feels. In physics, temperature is defined as the average kinetic energy of the particles in an object. When particles move more quickly, temperature is higher and an object feels warmer. When particles move more slowly, temperature is lower and an object feels cooler. If two objects have the same mass, the object with the higher temperature has greater thermal energy. Temperature affects thermal energy, but temperature isnt the same thing as thermal energy. Thats because an objects mass also affects its thermal energy. The examples in Figure 18.1 make this clear. In the figure, the particles of cocoa are moving faster than the particles of bathwater. Therefore, the cocoa has a higher temperature. However, the bath water has more thermal energy because there is so much more of it. It has many more moving particles. Bill Nye the Science Guy cleverly discusses these concepts at this URL: MEDIA Click image to the left or use the URL below. URL: If youre still not clear about the relationship between temperature and thermal energy, watch the animation "Tem- perature" at this URL: . Temperature is measured with a thermometer. A thermometer shows how hot or cold something is relative to two reference temperatures, usually the freezing and boiling points of water. Scientists often use the Celsius scale for temperature. On this scale, the freezing point of water is 0C and the boiling point is 100C. To learn more about measuring temperature, watch the animation Measuring Temperature at this URL: Did you ever wonder how a thermometer works? Look at the thermometer in Figure 18.2. Particles of the red liquid have greater energy when they are warmer, so they move more and spread apart. This causes the liquid to expand and rise higher in the glass tube. Like the liquid in a thermometer, most types of matter expand to some degree when they get warmer. Gases usually expand the most when heated, followed by liquids. Solids generally expand the least. (Water is an exception; it takes up more space as a solid than as a liquid.) Something that has a high temperature is said to be hot. Does temperature measure heat? Is heat just another word for thermal energy? The answer to both questions is no. Heat is the transfer of thermal energy between objects that have different temperatures. Thermal energy always moves from an object with a higher temperature to an object with a lower temperature. When thermal energy is transferred in this way, the warm object becomes cooler and the cool object becomes warmer. Sooner or later, both objects will have the same temperature. Only then does the transfer of thermal energy end. For a visual explanation of these concepts, watch the animation "Temperature vs. Heat" at this URL: . Figure 18.3 illustrates an example of thermal energy transfer. Before the spoon was put into the steaming hot coffee, it was cool to the touch. Once in the coffee, the spoon heated up quickly. The fast-moving particles of the coffee transferred some of their energy to the slower-moving particles of the spoon. The spoon particles started moving faster and became warmer, causing the temperature of the spoon to rise. Because the coffee particles lost some of their kinetic energy to the spoon particles, the coffee particles started to move more slowly. This caused the temperature of the coffee to fall. Before long, the coffee and spoon had the same temperature. The girls in Figure 18.4 are having fun at the beach. Its a warm, sunny day, and the sand feels hot under their bare hands and feet. The water, in contrast, feels much cooler. Why does the sand get so hot while the water does not? The answer has to do with specific heat. Specific heat is the amount of energy (in joules) needed to raise the temperature of 1 gram of a substance by 1C. Specific heat is a property that is specific to a given type of matter. Table 18.1 lists the specific heat of four different substances. Metals such
Question: transfer of thermal energy between objects with different temperatures | [
"heat"
] | task469-7dfae98c8af141998ce66306d89d21f7 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Sweet Weaponry is the first studio album by the pop punk band Cruiserweight.
Question: Who sang or played Sweet Weaponry? | [
"cruiserweight"
] | task469-5312aecfdaa84b3a96f48ebb3e9fc5a7 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Direct oral anticoagulants (DOACs) offer noninferior efficacy and improved safety compared to vitamin K antagonists (VKAs) for the prevention and treatment of venous thromboembolism and for the prevention of stroke and systemic embolism in nonvalvular atrial fibrillation. Unlike VKAs, DOACs do not require routine laboratory monitoring of anticoagulant effect and dose adjustment. In certain situations, however, laboratory assessment of anticoagulant effect may be desirable. Here we review the utility of currently available assays for assessment of DOAC effect and recommend an optimal assessment strategy for each drug, including calibrated dilute thrombin time or ecarin-based assays for dabigatran and calibrated anti-Xa activity assays for the factor Xa inhibitors. We also discuss reversal strategies, both specific and nonspecific, for each drug, including the preferential use of idarucizumab for the reversal of dabigatran and two agents, andexanet and ciraparantag, currently under development for the reversal of rivaroxaban, apixaban, and edoxaban.
Question: Which drug can be reversed with idarucizumab? | [
"dabigatran"
] | task469-f394d57232e441179a930322cf4f0fc7 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Coming off their home win over the Lions, the 49ers flew to the Louisiana Superdome for a Week 4 duel with the New Orleans Saints. In the first quarter, the Niners struck first as kicker Joe Nedney got a 47-yard field goal. In the second quarter, the Saints took the lead with QB Drew Brees completing a 5-yard and a 33-yard TD pass to WR Lance Moore. San Francisco would answer with Nedney's 49-yard field goal, yet New Orleans replied with Brees' 47-yard TD pass to WR Robert Meachem. In the third quarter, the 49ers tried to rally as Nedney kicked a 38-yard field goal. However, in the fourth quarter, the Saints continued to pull away as RB Deuce McAllister got a 1-yard TD run. The Niners tried to rally as QB J.T. O'Sullivan completed a 5-yard TD pass to WR Isaac Bruce, yet New Orleans sealed the win with kicker Martin Gramatica nailing a 31-yard field goal.
Question: How many yards was the longest field goal of the first half? | [
"49-yard"
] | task469-99d587d89e8c48a3b71dc2f5ebc49ec1 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: As of the census of 2000, there were 445,342 people, 169,162 households, and 114,015 families residing in the county. The population density was 615 people per square mile (238/km). There were 178,913 housing units at an average density of 247 per square mile (95/km). The racial makeup of the county was 82.19% Race (United States Census), 1.15% Race (United States Census) or Race (United States Census), 0.65% Race (United States Census), 6.68% Race (United States Census), 0.30% Race (United States Census), 5.86% from Race (United States Census), and 3.17% from two or more races. 11.17% of the population were Race (United States Census) or Race (United States Census) of any race. 17.2% were of German American, 9.9% English American, 8.2% Irish American, and 6.7% Americans ancestry. 81.7% spoke only English at home, while 9.6% spoke Spanish and 1.2% Vietnamese.
Question: Which group from the census in the county is larger: German American or Irish American? | [
"german american"
] | task469-d0290054a3624a839be1ebc1c5c243ab | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Parkinson's disease is the most common neurodegenerative movement disorder. -Synuclein is a small synaptic protein that has been linked to familial Parkinson's disease (PD) and is also the primary component of Lewy bodies, the hallmark neuropathology found in the brain of sporadic and familial PD patients. The function of -synuclein is currently unknown, although it has been implicated in the regulation of synaptic vesicle localization or fusion. Recently, overexpression of -synuclein was shown to cause cytoplasmic vesicle accumulation in a yeast model of -synuclein toxicity, but the exact role -synuclein played in mediating this vesicle aggregation is unclear. Here, we show that -synuclein induces aggregation of many yeast Rab GTPase proteins, that -synuclein aggregation is enhanced in yeast mutants that produce high levels of acidic phospholipids, and that -synuclein colocalizes with yeast membranes that are enriched for phosphatidic acid. Significantly, we demonstrate that -synuclein expression induces vulnerability to perturbations of Ypt6 and other proteins involved in retrograde endosome-Golgi transport, linking a specific trafficking defect to -synuclein phospholipid binding. These data suggest new pathogenic mechanisms for -synuclein neurotoxicity.
Question: Which is the primary protein component of Lewy bodies? | [
"αsyn",
"α-synuclein",
"alpha-synuclein"
] | task469-c896035d38ba45239e279bf6f246aaf8 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Conquest of Melilla occurred in September 1497, when a fleet sent by the Duke of Medina Sidonia seized the north African city of Melilla., as continuation of Reconquest of Mauritania Tingitana During the 15th century the mediterranean cities of the Sultanate of Fez fell in decadence in opposition to cities located in the Atlantic facade, which concentrated most of the economic activity. By the end of the 15th century, the port of Melilla, that had been often disputed between the rulers of Fez and Tlemcen, was nearly abandoned. Plans for the conquest occurred as soon as the Fall of Granada in 1492. Spanish captains Lezcano and Lorenzo Zafra visited the coast of Northern Africa to identify possible locations for the Spanish to overtake, and Melilla was identified as a prime candidate. Melilla was, however, in the Portuguese zone of influence under the terms of the 1479 Treaty of Alcacovaz. At Tordesillas in 1494, King John II of Portugal, the Portuguese ruler agreed to make an exception and permitted the Spanish to attempt the conquest of Melilla. The duke sent Pedro Estopinan who conquered the city virtually without a fight in 1497, as internal conflicts had depleted it of troops, and its defenses were weakened. The Wattasid ruler Muhammad al-Shaykh sent a detachment of cavalrymen to retake control of the city, but they were repulsed by the guns of the Spanish ships.
Question: Which happened first, the fleet being sent by the Duke of Medina, or the Conquest of Melilla? | [
"fleet sent by the duke"
] | task469-3dd754d75fe34379a80413a39a63d524 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Restriction endonucleases play a very important role in genetic engineering and DNA mapping. Among hundreds of restriction endonucleases, the Eco R1 enzyme is the most useful and widely investigated enzyme. After sonication and ultracentrifugation, crude extracts of E. coli RY 13 were purified by employing the polyethyleneimine precipitate, ammonium sulfate precipitate and heparin Sepharose-4B affinity column chromatography. The Eco R1 enzyme were purified at about 42 folds and the specific activity was about 100,000 U/mg of protein. The whole purification procedure was finished within two days. The recovery was about 42%. The enzyme was sufficiently concentrated for direct specific DNA hydrolysis.
Question: Which bacteria was EcoRI, restriction endonuclease isolated from? | [
"e coli"
] | task469-5af3684548094b4d9d78f92a8643e403 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: A dash of style with loads of attitude and a hunger to reach the stars, Lafangey Parindey is about a group of youngsters living in the backstreets of Mumbai. It is an unusual love story of Nandu (Neil Nitin Mukesh) and Pinky (Deepika Padukone) whose path to love is paved by friendship, grit and hope.He is wild. He is born to fight. He is One-Shot Nandu. For the raw, champion street fighter, one-shot is literally what it takes. Absolutely wild, fierce, and hungry to win, this fighter takes boxing to a new level by knocking down his opponents BLINDFOLDED. Needless to say, One-Shot lives life on his own terms and is a local hero amongst his friends. But all that soon changes, when he meets Pinky Palkar.She is blind. She is born to fly. She is Pinky Palkar. A unique girl, a powerhouse of talent! On one hand she works at a regular, boring 9-to-5 job at a mall but on the other hand, she is a kickass dancer on skates! Strong headed, talented and fiercely ambitious these traits make up Pinky Palkar's deadly personality. Her life's ambition is only one to rise above all the 'losers' living in her locality and carve a niche for herself. She will use her talent to show the others that she can win in life. There is only one, tiny, obstacle She is blind.Lafangey Parindey. Two different personalities. Two different lives. Destined to meet.Set in the grungy streets of Mumbai, Lafangey Parindey is an unusual, edgy love story about the never say die spirit even when your last chip is down. It is an intriguing journey of a blindfolded street fighter and a blind dancer who, along with four friends, set out to achieve the impossible.Born wild, will one-shot Nandu ever learn to love? Born to fly, will Pinky Palkar ever learn to see?
Question: Who is Pinky Palkar's partner in the competition? | [
"neil nitin mukesh"
] | task469-bf1f892f1b4e427e91233fc568995375 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Charles McNeill Gray (March 7, 1807 in Sherburne, New York - October 17, 1885; buried in Graceland Cemetery) served as Mayor of Chicago, Illinois (1853--1854) for the Democratic Party.
Question: Where was Charles McNeill Gray burried? | [
"graceland cemetery"
] | task469-3df0d784ec3b4f47a43267be257a97c6 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The 2010 United States Census reported that Marin County had a population of 252,409. The racial makeup of Marin County was 201,963 (80.0%) White (U.S. Census), 6,987 (2.8%) African American (U.S. Census), 1,523 (0.6%) Native American (U.S. Census), 13,761 (5.5%) Asian (U.S. Census), 509 (0.2%) Pacific Islander (U.S. Census), 16,973 (6.7%) from Race (United States Census), and 10,693 (4.2%) from two or more races. Hispanic (U.S. Census) or Latino (U.S. Census) of any race were 39,069 persons (15.5%).
Question: Which group from the census is smaller: Asian or two or more races? | [
"two or more races"
] | task469-8f31567bdaee45fdbbdf4d145bef847c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Tamas Lukacs (born 29 March 1950) is a Hungarian jurist and politician, former Member of Parliament from 1990 to 1994 and from 2006 to 2014.
Question: The date of birth for Tamas Lukacs is what? | [
"29 march 1950"
] | task469-ddc74cd6b7194bdeb5fd53d47a65182b | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: A pulley is a simple machine that consists of a rope and grooved wheel. The rope fits into the groove in the wheel, and pulling on the rope turns the wheel. Pulleys are generally used to lift objects, especially heavy objects. The object lifted by a pulley is called the load. The force applied to the pulley is called the effort. Q: Can you guess what the pulley pictured above is used for? A: The pulley is used to lift heavy buckets full of water out of the well. Some pulleys are attached to a beam or other secure surface and remain fixed in place. They are called fixed pulleys. Other pulleys are attached to the object being moved and are moveable themselves. They are called moveable pulleys. Sometimes, fixed and moveable pulleys are used together. They make up a compound pulley. The three types of pulleys are compared in the Table 1.1. Q: Which type of pulley is the old pulley in the opening image? A: The old pulley is a single fixed pulley. It is securely attached to the beam above it. Type of Pulley How It Works Example Single fixed pul- ley Flagpole pulley No. of Rope Segments Pulling Up 1 Ideal Mechani- cal Advantage 1 Change Direction Force? yes Single moveable pulley Zip-line pulley 2 2 no Compound pulley (fixed & moveable pulleys) Crane pulley 2 2 varies in of The mechanical advantage of a simple machine such as a pulley is the factor by which the machine changes the force applied to it. The ideal mechanical advantage of a machine is its mechanical advantage in the absence of friction. All machines must overcome friction, so the ideal mechanical advantage is always somewhat greater than the actual mechanical advantage of the machine as it is used in the real world. In a pulley, the ideal mechanical advantage is equal to the number of rope segments pulling up on the object. The more rope segments that are helping to do the lifting work, the less force that is needed for the job. Look at the table of types of pulleys. It gives the ideal mechanical advantage of each type. In the single fixed pulley, only one rope segment pulls up on the load, so the ideal mechanical advantage is 1. In other words, this type of pulley doesnt increase the force that is applied to it. However, it does change the direction of the force. This allows you to use your weight to pull on one end of the rope and more easily raise the load attached to the other end. In the single moveable pulley, two rope segments pull up on the load, so the ideal mechanical advantage is 2. This type of pulley doesnt change the direction of the force applied to it, but it increases the force by a factor of 2. In a compound pulley, two or more rope segments pull up on the load, so the ideal mechanical advantage is 2 or greater than 2. This type of pulley may or may not change the direction of the force applied to itit depends on the number and arrangement of pulleysbut the increase in force may be great. Q: If a compound pulley has four rope segments pulling up on the load, by what factor does it multiply the force applied to the pulley? A: With four rope segments, the ideal mechanical advantage is 4. This means that the compound pulley multiplies the force applied to it by a factor of 4. For example if 400 Newtons of force were applied to the pulley, the pulley would apply 1600 Newtons of force to the load.
Question: which type(s) of pulley can have a mechanical advantage greater than 2? | [
"compound pulley"
] | task469-fc80671d140c4d2fa85633a4b1d96c1c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: We compared the safety and efficacy of siltuximab (S), an anti-interleukin-6 chimeric monoclonal antibody, plus bortezomib (B) with placebo (plc) + B in patients with relapsed/refractory multiple myeloma in a randomized phase 2 study. Siltuximab was given by 6 mg/kg IV every 2 weeks. On progression, B was discontinued and high-dose dexamethasone could be added to S/plc. Response and progression-free survival (PFS) were analyzed pre-dexamethasone by European Group for Blood and Marrow Transplantation (EBMT) criteria. For the 281 randomized patients, median PFS for S + B and plc + B was 8.0 and 7.6 months (HR 0.869, P = 0.345), overall response rate was 55 versus 47% (P = 0.213), complete response rate was 11 versus 7%, and median overall survival (OS) was 30.8 versus 36.8 months (HR 1.353, P = 0.103). Sustained suppression of C-reactive protein, a marker reflective of inhibition of interleukin-6 activity, was seen with S + B. Siltuximab did not affect B pharmacokinetics. Siltuximab/placebo discontinuation (75 versus 66%), grade 3 neutropenia (49 versus 29%), thrombocytopenia (48 versus 34%), and all-grade infections (62 versus 49%) occurred more frequently with S + B. The addition of siltuximab to bortezomib did not appear to improve PFS or OS despite a numerical increase in response rate in patients with relapsed or refractory multiple myeloma.
Question: Which interleukin is blocked by Siltuximab? | [
"interleukin-6"
] | task469-276c8983d68f4e1aa10af93a8d064453 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Weathering changes solid rock into sediments. Sediments are different sizes of rock particles. Boulders are sedi- ments; so is gravel. At the other end, silt and clay are also sediments. Weathering causes rocks at the Earths surface to change form. The new minerals that form are stable at the Earths surface. It takes a long time for a rock or mountain to weather. But a road can do so much more quickly. If you live in a part of the world that has cold winters, you may only have to wait one year to see a new road start to weather (Figure Mechanical weathering breaks rock into smaller pieces. These smaller pieces are just like the bigger rock; they are just smaller! The rock has broken without changing its composition. The smaller pieces have the same minerals in the same proportions. You could use the expression a chip off the old block to describe mechanical weathering! The main agents of mechanical weathering are water, ice, and wind. Rocks can break apart into smaller pieces in many ways. Ice wedging is common where water goes above and below its freezing point (Figure 9.2). This can happen in winter in the mid-latitudes or in colder climates in summer. Ice wedging is common in mountainous regions. This is how ice wedging works. When liquid water changes into solid ice, it increases in volume. You see this when you fill an ice cube tray with water and put it in the freezer. The ice cubes go to a higher level in the tray than the water. You also may have seen this if you put a can of soda into the freezer so that it cools down quickly. If you leave the can in the freezer too long, the liquid expands so much that it bends or pops the can. (For the record, water is very unusual. Most substances get smaller when they change from a liquid to a solid.) Abrasion is another type of mechanical weathering. With abrasion, one rock bumps against another rock. Gravity causes abrasion as a rock tumbles down a slope. Moving water causes abrasion it moves rocks so that they bump against one another (Figure 9.3). Strong winds cause abrasion by blasting sand against rock surfaces. Finally, the ice in glaciers cause abrasion. Pieces of rock embedded in ice at the bottom of a glacier scrape against the rock below. If you have ever collected beach glass or pebbles from a stream, you have witnessed the work of abrasion. Sometimes biological elements cause mechanical weathering. This can happen slowly. A plants roots grow into a crack in rock. As the roots grow larger, they wedge open the crack. Burrowing animals can also cause weathering. By digging for food or creating a hole to live in the animal may break apart rock. Today, human beings do a lot of mechanical weathering whenever we dig or blast into rock. This is common when we build homes, roads, and subways, or quarry stone for construction or other uses. Mechanical weathering increases the rate of chemical weathering. As rock breaks into smaller pieces, the surface area of the pieces increases. With more surfaces exposed, there are more places for chemical weathering to occur. Lets say you wanted to make some hot chocolate on a cold day. It would be hard to get a big chunk of chocolate to dissolve in your milk or hot water. Maybe you could make hot chocolate from some smaller pieces like chocolate chips, but it is much easier to add a powder to your milk. This is because the smaller the pieces are, the more surface area they have. Smaller pieces dissolve more easily. Chemical weathering is different than mechanical weathering. The minerals in the rock change. The rock changes composition and becomes a different type of rock. Most minerals form at high pressure or high temperatures deep within Earth. But at Earths surface, temperatures and pressures are much lower. Minerals that were stable deeper in the crust are not stable at the surface. Thats why chemical weathering happens. Minerals that formed at higher temperature and pressure change into minerals that are stable at the surface. Chemical weathering is important. It
Question: type of weathering that breaks rock into smaller pieces | [
"mechanical weathering"
] | task469-1423c51c900f41d599580a9d37c68d13 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The fourteenth week of the season featured a game between 5-7 teams as the Washington Redskins visited Soldier Field. In 48 games, the Redskins led the series 24-23-1 and had won the last five meetings. The Chicago offense took on a Washington defense that excelled against passers, being ranked tenth in the category; Dashon Goldson led all defensive backs in tackles with 95, while Bashaud Breeland led the team in passes defended with 13. The Redskins defensive rush, which had 20 sacks in 2015, was led by Ryan Kerrigan, who has 6.5. Despite such performances, the Redskins rush defense was ranked 29th in yards per carry with 4.64 and 25th in average rushing yards at 124.2. Jeff Joniak writes that the Bears could exploit this with the three-man rushing attack of Matt Forte, Jeremy Langford, and Ka'Deem Carey. On defense, the Bears faced a Kirk Cousins-led offense that focuses on quick passes; Cousins completed a league-high 68.6 percent of his passes, with 7.1 yards per pass. One of Cousins' main targets was tight end Jordan Reed, who scored six touchdowns and led the Redskins in yards after the catch. Rankings-wise, the pass attack was ranked 17th in the league in passing yards per game and 16th for yards per play. Joniak states that the Bears had to force turnovers, and an area was on third down, as five of Cousins' interceptions had been on third down. The Bears won the coin toss and elected to defer. Washington recorded a 15-play, 80-yard drive en route to scoring on Alfred Morris' one-yard touchdown run. After the Bears punted, the Redskins scored again with Cousins' fake read option leading to a three-yard touchdown run in the second quarter. Chicago's woes continued when the offense began the next drive on their own seven-yard line, and despite reaching the Washington 49, Jay Cutler was strip-sacked by Trent Murphy, who recovered the fumble. The Redskins failed to capitalize on the turnover and punted; the following two drives also ended with punts. With 52 seconds left in the first half, the Bears took over at their own 42, and managed to score with 18 seconds left when Cutler threw a 20-yard touchdown pass to Alshon Jeffery. Cousins kneeled once to end the half. After the Bears punted on the first drive of the second half, Cousins threw a five-yard touchdown pass to Reed. The Bears responded with Cutler's nine-yard touchdown pass to Zach Miller, who managed to escape DeAngelo Hall and made contact with Goldson as he reached the endzone. The score was the Bears' first third quarter touchdown of 2015. Afterwards, Cousins' pass for Pierre Garcon was intercepted by Kyle Fuller, and the Bears took advantage with Forte's seven-yard touchdown run to tie the score. Dustin Hopkins gave the Redskins the 24-21 lead on the first drive of the final quarter with a 47-yard field goal. Five drives later, the Bears attempted a 50-yard field goal with 1:40 left in the game. However, Robbie Gould's kick sailed wide left, and the Redskins ran the ball three times to end the game.
Question: Who caught the first touchdown pass of the second half? | [
"reed"
] | task469-d0a8d3041f8f4d11854262375c7ddbc3 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Dolphins' eighth game was an AFC duel with the Ravens. The Dolphins trailed early after QB Joe Flacco completed a 32-yard TD pass to RB Willis McGahee. They replied with RB Ronnie Brown getting a 12-yard TD run. The Ravens got the lead back after kicker Billy Cundiff made a 26 and a 39-yard field goal. The Dolphins narrowed the lead with kicker Dan Carpenter nailing a 19-yard field goal. The Dolphins fell further behind after Flacco found WR Derrick Mason on a 12-yard TD pass. This was followed in the 4th quarter by Cundiff hitting a 20 and a 24-yard field goal.
Question: Which kickers had at least three field goals? | [
"billy cundiff"
] | task469-9b6f8541a1064f52a742b92932c60836 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Neutrophil elastase gene (ELANE) mutations are responsible for the majority of cases of severe congenital neutropenia (CN) and cyclic neutropenia (CyN). We screened CN (n=395) or CyN (n=92) patients for ELANE mutations and investigated the impact of mutations on mRNA expression, protein expression, and activity. We found 116 different mutations in 162 (41%) CN patients and 26 in 51 (55%) CyN patients, 69 of them were novel. CyN-associated mutations were predicted to be more benign than CN-associated mutations, but the mutation severity largely overlapped. The frequency of acquired CSF3R mutations, malignant transformation, and the need for hematopoietic stem cell transplantation was significantly higher in CN patients with ELANE mutation than in ELANE mutation negative patients. Cellular elastase activity was reduced in neutrophils from CN/CyN patients, irrespective of the mutation status. In CN, enzymatic activity was significantly lower in patients with ELANE mutations compared with those with wild-type ELANE. Despite differences in the spectrum of mutations in CN or CyN, type or localization of mutation only partially determine the clinical phenotype. Specific ELANE mutations have limited predictive value for leukemogenesis; the risk for leukemia was correlated with disease severity rather than with occurrence of an ELANE mutation.
Question: Which gene is most commonly associated with severe congenital and cyclic neutropenia? | [
"the neutrophil elastase gene (elane)"
] | task469-f536b44fe7584d308eb7841b98ae6cd0 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: In 2009 Fukushimas industries directly employed 18,678 workers and shipped 671 billion worth of goods. This was led by information-related industries with 50.5% of total output. Other industries in Fukushima include those dealing with food at 7.6% of total output, metals at 7.5%, chemistry at 5.3%, ceramics at 4.9%, electricity at 4.5%, printed goods at 2.8%, steel at 2.5%, plastics at 2.5%, and electronics at 2.2%. Other various industries make up the final 9.8%.
Question: Which group of industries in Fukushima is larger: metals or chemistry? | [
"metals"
] | task469-1d067134e63f41a8a7fcfce8aa4ad574 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Nicholas Barre, O.M. (21 October 1621 -- 31 May 1686), was a French Minim friar and Catholic priest, who founded the Sisters of the Infant Jesus.
Question: What group was Nicholas Barre a member of? | [
"minim"
] | task469-f24d1c15ea9e4417b2fc303bd355acf1 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Earthquake magnitude affects how much damage is done in an earthquake. A larger earthquake damages more buildings and kills more people than a smaller earthquake. But thats not the only factor that determines earthquake damage. The location of an earthquake relative to a large city is important. More damage is done if the ground shakes for a long time. The amount of damage also depends on the geology of the region. Strong, solid bedrock shakes less than soft or wet soils. Wet soils liquefy during an earthquake and become like quicksand. Soil on a hillside that is shaken loose can become a landslide. Hazard maps help city planners choose the best locations for buildings (Figure 7.38). For example, when faced with two possible locations for a new hospital, planners must build on bedrock rather than silt and clay. The 1985 Mexico City earthquake measured magnitude 8.1. The earthquake killed at least 9,000 people, injured 30,000 more, and left 100,000 people homeless. It destroyed 416 buildings, and seriously damaged 3,000 other buildings. The intense destruction was due to the soft ground the city is built on. Silt and clay fill a basin made of solid rock. In an earthquake, seismic waves bounce back-and-forth off the sides and bottom of the rock basin. This amplifies the shaking. The wet clay converts to quicksand (Figure 7.39). Many buildings were not anchored to bedrock. They settled into the muck. This caused enormous damage. Water, sewer, and electrical systems were destroyed, resulting in fires. Acapulco was much closer to the epicenter, but since the city is built on bedrock it suffered little damage. The amount of damage depends on the amount of development in the region. The 1964 Great Alaska Earthquake, near Anchorage, was the largest earthquake ever recorded in North America. The gigantic quake had a magnitude of 9.2. The earthquake lasted for several minutes and the ground slipped up to 11.5 meters (38 feet). An area of 100,000 square miles (250,000 square km) was affected. The ground liquefied, causing landslides (Figure 7.40). The earthquake occurred at a subduction zone, and large tsunami up to 70 meters (20 feet) high were created. Despite the intensity of the earthquake, only 131 people died. Most deaths were due to the tsunami. Property damage was just over $300 million ($1.8 billion in 2007 U.S. dollars). The reason there was such a small amount of damage is that very few people lived in the area (Alaska had only been a state for five years!). A similar earthquake today would affect many more people. Buildings must be specially built to withstand earthquakes. Skyscrapers and other large structures built on soft ground must be anchored to bedrock. Sometimes that bedrock is hundreds of meters below the ground surface! Building materials need to be both strong and flexible. Small structures, like houses, should bend and sway. Wood and steel bend. Brick, stone, and adobe are brittle and will break. Larger buildings must sway, but not so much that they touch nearby buildings. Counterweights and diagonal steel beams can hold down sway. Buildings need strong, flexible connections where the walls meet the foundation. Earthquake-safe buildings are well connected (Figure Steel or wood can be added to older buildings to reinforce a buildings structure and its connections (Figure 7.42). Elevated freeways and bridges can also be reinforced so that they do not collapse. Important structures must be designed to survive intact. One of the biggest problems caused by earthquakes is fire. Fires start because earthquakes rupture gas and electrical lines. Water mains may break. This makes it difficult to fight the fires. The shapes of pipes can make a big difference. Straight pipes will break in a quake. Zigzag pipes bend and flex when the ground shakes. In San Francisco, water and gas pipelines are separated by valves. Areas can be isolated if one segment breaks. Strong, sturdy structures are expensive to build. Communities must decide how safe to make their buildings. They must weigh how great the hazard is, what different building strategies will cost, and how much risk they are
Question: material that forms when wet soil shakes and liquefies in an earthquake | [
"quicksand"
] | task469-269441983bc248a0871b4bd47788e122 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
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