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This report suggests that anemia can occur due to MMF, in particular when it is given with prednisone, a side effect well documented in the transplantation literature when the triple combination of MMF, cyclosporine and prednisone is used.
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Human immunodeficiency virus (HIV) protease inhibitors are associated with several metabolic abnormalities including hypercholesterolemia and hypertriglyceridemia.
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Succinylcholine-induced hyperkalemia in a patient with mucositis secondary to chemotherapy.
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BACKGROUND: Serotonin syndrome (SS) and neuroleptic malignant syndrome (NMS) are medical emergencies associated with psychotropic administration.
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Gastro-intestinal side-effects, however, have not been reported in clinical studies dealing with treatment of vasospasm following subarachnoid haemorrhage.
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Computed brain tomography was normal.
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A patient with chronic myelomonocytic leukemia developed drug-induced pulmonary toxicity after using low dose oral etoposide.
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Acute vision loss after intravitreal injection of bevacizumab (avastin) associated with ocular ischemic syndrome.
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Energy-dispersive X-ray microanalysis showed the presence of several metals not seen in normal bone.
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During surgery the left internal jugular vein was found to be thrombosed and, therefore, ligated and resected.
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Dramatic clinical improvement followed prednisone therapy.
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After therapy for diabetic coma with insulin (containing the preservative cresol) and electrolyte solutions was started, the patient complained of increasing myalgia, developed a high fever and respiratory and metabolic acidosis and lost consciousness.
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The patient tolerated amoxicillin and cefazolin, suggesting that the sensitizing portion was not the beta-lactam ring.
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A 32-year-old woman with lazy bladder was treated with cisapride (10 mg q.i.d.) for three weeks, obtaining a progressive improvement of the symptomatology and urodynamic parameters, and the return to pretreatment conditions after drug withdrawal.
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Recombinant human granulocyte colony-stimulating factor in combination with continuous infusion of cytosine arabinoside for the treatment of refractory acute myelogenous leukemia.
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BACKGROUND: Superficial basal cell carcinoma can be successfully managed by means other than surgical excision.
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Later, confirmatory urine testing of both patients using high-performance liquid chromatography was negative for tricyclic antidepressants.
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Development of essential thrombocythemia in a patient treated with interferon alfa and pentostatin for hairy cell leukemia.
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Patients with cancer are especially vulnerable to the development of hyper- and hypocalcemia.
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A 7-year-old boy with asthma was receiving the leukotriene receptor antagonist pranlukast (Ultair; SmithKline Beecham; Pittsburgh) as part of an open-label clinical trial.
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CONCLUSIONS: The need for prophylactic anticonvulsant therapy especially utilizing phenytoin in patients undergoing cranial radiation therapy should be assessed on a case by case basis.
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Another patient had a brief relapse two years after the first episode, after a single therapeutic dose of another clioquinol preparation.
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Her course, history and outcome are presented and the pharmacokinetics, the mechanism of action, signs and symptoms and treatment of strychnine poisoning are reviewed.
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However, the left ventricular ejection fraction was severely decreased (26%), and new regional wall motion abnormalities typical of broken heart syndrome were noted.
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We observed an unexpectedly rapid rise in platelet counts with complete haematological recovery after a BEAM regimen, in a patient who could not be rescued by autologous transplant but who received filgrastim, epoetin alfa, and ancestim.
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On postburn day 31, he developed a temperature of 108.4 degrees F (42.4 degrees C).
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Preventive medications reduce migraine frequency and severity, and improve migraine-specific quality of life.
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CONCLUSION: This case identifies another potential etiological factor in the development of TMA after renal transplantation.
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CONCLUSION: Hypersensitivity reaction should be considered in patients who develop recurrent eosinophilia and deterioration of pulmonary function following the use of tobramycin by inhalation or by intravenous administration.
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When patients are prescribed tolterodine and warfarin concurrently, clinicians should monitor INR carefully, and a reduction in warfarin dosage may be required.
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The cumulative severity of thrombocytopenia observed over successive cycles was accompanied by an increasing TPO response which tended to grow overproportionally in relation to the degree of peripheral thrombocytopenia.
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CONCLUSIONS: Our analysis of the published case reports suggests a causal association between green tea and liver damage.
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Though proteinuria and nephrotic syndrome is a rare adverse effect of IFN-beta-1b therapy, physicians treating MS patients with this agent should pay careful attention to new clinical symptoms and laboratory findings.
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The AUC was between 0 and 6 X 10 ng X min/ml, and AUC normalized to 1 mg/m2 of 6MP was between 0 and 815 ng X min/ml.
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BACKGROUND: Interferon (IFN)-associated retinopathy is typically characterized by retinal hemorrhages and cotton wool spots at the posterior fundus, but visual function is usually maintained.
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Does acyclovir increase serum lithium levels?
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CONCLUSION: Our case shows a fatal side effect of erlotinib.
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Tumor necrosis factor alpha (TNF-alpha) inhibitors, such as infliximab, decrease the body's inflammatory response and thus the body's reaction to infection.
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BACKGROUND: Bacterial contamination of platelet (PLT) components is an important cause of transfusion reactions.
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She underwent a general ophthalmological investigation, perimetry and electroretinographic examination with multifocal (m-ERG) and flash-electroretinogram (flash-ERG).
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Adenomyosis in the broad ligament and tamoxifen: report of a case.
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We propose that, in addition to hyperperfusion, captopril alters renal function by an additional intrarenal hemodynamic effect.
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After therapy for diabetic coma with insulin (containing the preservative cresol) and electrolyte solutions was started, the patient complained of increasing myalgia, developed a high fever and respiratory and metabolic acidosis and lost consciousness.
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Agranulocytosis resolved 4 days following withdrawal of teicoplanin.
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This case illustrates the broad clinical spectrum of angioimmunoblastic lymphadenopathy with dysproteinemia and suggests that aggressive treatment is necessary in selected patients.
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Simultaneously, systemic dexamethasone and calcium folinic acid were given.
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CONCLUSIONS: Topiramate may be associated with ciliochoroidal effusion with forward displacement of the lens-iris diaphragm and anterior chamber shallowing, resulting in acute myopia and angle-closure glaucoma.
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Suspected inappropriate secretion of antidiuretic hormone in a male with mental retardation.
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We present two cases of nitrofurantoin-induced pulmonary toxicity in which the initial HRCT showed a widespread reticular pattern and associated distortion of the lung parenchyma, thought to represent established fibrosis.
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Quetiapine (Seroquel) is an atypical antipsychotic drug belonging to a new chemical class, the benzothiazepine derivatives.
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The fetal valproate syndrome (FVS) is characterized by distinctive facial appearance, major and minor malformations, and developmental delay.
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She received 3.8 mg cumulative dose of vincristin before development of ptosis.
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BACKGROUND: Reproductive endocrine disorders characterized by menstrual disorders, polycystic ovaries, and hyperandrogenism seem to be common among women treated with sodium valproate for epilepsy.
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The patient is currently under treatment with prednisone 20 mg/day for systemic lupus erythematosus and with oral mesalazine 2.4 mg/day for Crohn's disease.
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Pheripheral edema was observed in five female patients after taking proton pump inhibitors omeprazole, lansoprazole, or pantoprazole for 7-15 days for peptic acid diseases in recommended standard doses.
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PURPOSE: To describe bilateral optic neuritis that occurred as an adverse effect of recombinant and natural interferon alpha administration.
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We indicate that initial and early treatment of the patients with DM and PnM with CsA enabled rapid tapering of the dose of glucocorticoid and improved the disease.
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Successful use of Shakuyaku-kanzo-to, a traditional herbal medicine, for intractable symptoms of thoracic outlet syndrome: a case report.
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A small dose of protamine sulphate was then administered, which promptly restored hemostasis.
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Nocardia exalbida brain abscess in a patient with follicular lymphoma.
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The patient was advised to stop administration of the mineral oil and was treated empirically with antibiotics during a 3-month period.
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One week after the initial-dose of adalimumab (160 mg), which was initiated due to an acute exacerbation of Crohn's disease, the patient developed a fulminant cardiomyopathy.
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In this case, it was suspected that a combination of cigarette smoking, pulmonary fibrosis, and low-dose methotrexate therapy might have promoted the development of lung cancer.
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He was later skin tested to confirm allergy to MTX.
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Baclofen withdrawal: a cause of prolonged fever in the intensive care unit.
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The authors report two cases of acute dystonic reactions (ADRs) as a side effect of lamivudine.
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RESULTS: One case of recurrent primary peritoneal carcinoma previously treated with a carboplatin-based regimen, developed a platinum hypersensitivity.
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Recently, a controversy has arisen as to whether air or saline should be recommended for the correct localization of the epidural space with the loss of resistance technique.
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This is a rare complication of bypass surgery and may be a cause of recurrent angina postoperatively due to coronary artery steal.
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In all except two patients, serum Na+ returned to normal values within 3 to 12 months of continued lorcainide therapy.
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The symptomatology of 18 other paediatric cases of naphthylimidazoline exposure reported to the Belgian National Poison Centre, is also discussed.
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The lesions were morphologically distinct and differed in their anatomical distribution during each episode.
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Use of perospirone for obesity and diabetes mellitus in patients with schizophrenia: three case reports.
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Both experts would obtain an audiogram after the acute problems are treated.
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Livedo reticularis associated with interferon alpha therapy in two melanoma patients.
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A case is reported in which severe hypocalcemia, with a low plasma parathyroid hormone (PTH) concentration, resulted from the therapeutic use of magnesium sulfate for toxemia of pregnancy.
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Ayurveda is an East Indian tradition involving the treatment of medical ailments through the use of herbal medications.
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We investigated the patient's serum for all frequent polymorphisms in cytochrome P450 2D6, assuming him to be a poor neuroleptic metabolizer.
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He had complex partial seizures refractory to several antiepileptic drugs since 4 years of age.
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The addition of certain substrates such as glutamine, arginine and omega-3 fatty acids may improve the body's immune response as well.
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Goiter and hypothyroidism during re-treatment with amiodarone in a patient who previously experienced amiodarone-induced thyrotoxicosis.
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These findings are significant not only in monitoring amiodarone effects during chronic prophylactic drug therapy but also in providing further insight into the complex interrelation between the action of the drug and the thyroid hormones on cardiac muscle.
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Persistent loss of tyrosine hydroxylase immunoreactivity in the substantia nigra after neuroleptic withdrawal.
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However, medications containing PPA still can be found in many homes of those unaware of the voluntary recall.
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Neither veno-occlusive disease nor thrombotic microangiopathy was documented.
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The current study investigated the visual fields and visual electrophysiology of eight patients with known vigabatrin-attributed visual field loss, three of whom were reported previously.
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For both the second and third patients, symptomatology failed to resolve until the intraperitoneal cisplatin solution was withdrawn.
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Patient responded dramatically to Stellate ganglion block and returned to work within two weeks time.
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Thus, the possible in vivo effects of insulin on adipocytes were clearly observed in this case of insulin-induced lipohypertrophy.
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Clinicians should be aware that an erythematous and exfoliative rash may be induced by temozolomide, and be familiar with the pharmacologic and supportive measures necessary for its treatment.
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We describe 2 patients with severe erosive rheumatoid arthritis and rheumatoid vasculitis, respectively, in whom infliximab therapy was associated with peripheral neuropathy due to necrotizing vasculitis in one patient and to progression of preexisting mononeuritis multiplex in the other.
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Benign pneumatosis intestinalis in a child with cavopulmonary shunt and immune thrombocytopenic purpura.
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Disseminated varicella infection in a child receiving short-term steroids for asthma.
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After prolonged recovery periods, only mild neurological deficits persisted in both patients.
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The mainstay of therapy has been potassium replacement, however, recent evidence suggests propranolol is a more effective therapy.
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As expected, we identified few successful cases of switches from clozapine in our search of the literature.
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We suggest, however, that the case against the drugs alone has yet to be proved.
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There was a prompt response to the ritodrine hydrochloride.
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INTERPRETATION: When high doses of fluticasone propionate are used, growth may be retarded and adrenal suppression may occur.
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Other reports are needed to establish whether such placental findings are common lesions after such therapy and to determine their impact on pregnancy outcome.
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