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Cultures demonstrated Aspergillus fumigatus sensitive to voriconazole.
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Based on a Naranjo score of 7, this episode was probably related to an interaction between acenocoumarol and econazole.
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Although a single case, this report questions the safety of using an intraoperative application of mitomycin C for preventing a recurrence of pterygium.
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OBJECTIVE: To report the use of oral terbutaline for chronotropic support in a patient who had undergone heart transplantation.
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The remaining 12 received three or more courses of treatment, and three of these patients achieved a complete response.
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It may represent a uveitic immune phenomenon.
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Syndrome of inappropriate antidiuretic hormone associated with vinorelbine therapy.
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CASE REPORTS: We report 3 patients with chronic schizophrenia who had previously stopped clozapine due to hematologic side effects.
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Clinicians should be aware of this potential life-threatening adverse reaction and monitor kidney function while patients are using linezolid.
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Daptomycin for eradication of a systemic infection with a methicillin-resistant-Staphylococcus aureus in a biventricular assist device recipient.
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A possible mechanism for this alarming outcome is discussed, and it is suggested that resuscitation facilities should be quickly available during such trials.
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Hyperkalaemia with renal tubular dysfunction by sulfamethoxazole-trimethoprim for Pneumocystis carinii pneumonia in patients with lymphoid malignancy.
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Plasmapheresis was discontinued, and intravenous ganciclovir was initiated.
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Ezetimibe-induced acute pancreatitis.
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The authors describe a case of the catatonia syndrome associated with disulfiram therapy.
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The patient recovered and the vagina mucosa healed within two weeks.
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A case report and review of the literature.
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Three of the patients had received no prior alkylating agents.
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Prednimustine is an ester of chlorambucil and prednisone.
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Severe leukopenia associated with mild hepatotoxicity in an HIV carrier treated with nevirapine.
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Recently, a number of prospective, randomized, double-blind trials have shown their success in the management of rheumatoid arthritis, with dapsone being superior to placebo and comparable to chloroquine and hydroxychloroquine.
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The acronym SILENT (Syndrome of Irreversible Lithium-Effectuated Neurotoxicity) has been coined recently to denote these sequelae.
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This case suggests the importance of careful observation for extramedullary relapse in patients who are treated with ATRA.
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DATA SYNTHESIS: Genetic deficiencies in DPD, the rate-limiting enzyme responsible for 5-FU catabolism, may occur in 3% or more of patients with cancer putting them at increased risk for unusually severe adverse reactions (e.g., diarrhea, stomatitis, mucositis, myelosuppression, neurotoxicity) to standard doses of 5-FU.
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Despite aggressive intensive care management, the patient died 17 days from the onset of symptoms due to multiple organ failure.
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The tympanic membrane perforation would be treated with antibiotic/steroid drops.
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We hypothesize that early glutamine supplemented tube feedings in children receiving intensive chemotherapy alone or in combination with bone marrow transplantation will result in improved nutrition with fewer infections and lower cost than TPN-supplemented patients.
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The Naranjo probability scale indicated a probable relationship between apnea and exposure to lamotrigine through breast-feeding in this infant.
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On colonoscopy, inflammatory lesions highly compatible with CD were found endoscopically and histologically in all patients.
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Eight to eleven months after starting treatment, TSHRAb positivity and intense scintigraphic uptake confirmed the appearance of Graves' disease.
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Ritonavir acted as a CYP3A4 inhibitor, diminishing carbamazepine metabolism and provoking an increase in serum levels and clinical toxicity.
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We report a series of three patients with HCC and platelet count < 60,000/mm(3) who were successfully treated with sorafenib with no complications.
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These HRCT findings were atypical compared with those of former bronchiolitis obliterans (BO) after bone marrow transplant (BMT).
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All were over 45 years of age, and premorbid kidney abnormalities may have enhanced susceptibility to toxic effects of the drug.
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In the present paper the authors describe 2 female patients who developed incontinence secondary to the selective serotonin reuptake inhibitors paroxetine and sertraline, as well as a third who developed this side effect on venlafaxine.
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This case report emphasizes the importance of routine vitamin D supplementation in all patients on long term cholestyramine therapy, and indicates that even in patients with small intestinal disease or resection, oral preparations of vitamin D or its metabolities and analogues may be effective.
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This case demonstrates the association of selective IgA deficiency with remission in rheumatoid arthritis induced by fenclofenac as well as aurothiomalate and sulphasalazine.
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Pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) and granulocyte colony-stimulating factor (G-CSF) promote haematopoietic progenitor cell maturation.
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Clofibrate-induced myopathy in patients with diabetes insipidus.
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A 4 year old boy with acute lymphoblastic leukaemia developed a pure red cell aplasia 13 months after entering remission and while on maintenance chemotherapy.
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The successful treatment of autoimmune hepatitis with 6-mercaptopurine after failure with azathioprine.
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The optimal treatment of IVC thrombosis has not been established to date.
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Development of bilateral herpes zoster following thoracoscopic splanchnicectomy.
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The cases are important in documenting that drug-induced dystonias do occur in patients with dementia, that risperidone appears to have contributed to dystonia among elderly patients, and that the categorization of dystonic reactions needs further clarification.
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Seizures and transient blindness following intravenous pulse methylprednisolone in children with primary glomerulonephritis.
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BACKGROUND: Electroporation is a process that causes a transient increase in the permeability of cell membranes.
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Deaths occurring during clinical studies of topical minoxidil.
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Methimazole-induced aplastic anemia in third exposure: successful treatment with recombinant human granulocyte colony-stimulating factor.
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The neurological symptoms and signs were headaches, right quadrant hemianopia, dyslexia without agraphia, motor aphasia, numbness in and weakness of the right upper extremity, papilloedema and coma.
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A 14-year-old female developed systemic lupus erythematosus (SLE)-like symptoms, rash, fever, leukopenia and positive anti-nuclear antibody (ANA) two weeks after administration of carbamazepine (CBZ; Tegretol) used against benign Rolandic epilepsy.
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Interferon-alpha-induced hyperthyroidism: a three-stage evolution from silent thyroiditis towards Graves' disease.
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Systemic and local factors influence growth of Candida in the stomach.
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Two days after the drug was discontinued, the duration of the QRS complex was normalized.
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BACKGROUND: Intravenous alteplase for acute ischemic stroke is least efficacious for patients with proximal large-artery occlusions and clinically severe strokes.
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Histologic evaluation was also performed before treatment and in selected patients during treatment.
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A case report revealing two previously unreported adverse side effects of meprobamate and tridihexethyl chloride (Milpath) drug therapy for a spastic colon is presented.
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Delusional disorder, somatic type treated with aripiprazole--mirtazapine combination.
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Several cases have been described in the United Kingdom and recently in the United States.
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Alternating sinus rhythm and intermittent sinoatrial block induced by propranolol.
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The disorders were characterized by hyperandrogenism and polycystic ovaries in all cases, and were associated with weight gain and menstrual disorders in 2 of the 3 women.
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Growth and adrenal suppression in asthmatic children treated with high-dose fluticasone propionate.
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Several hypotheses are advanced to explain the failure of bone erosions to heal.
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A patient with a large hydatid cyst of the left lobe of the liver developed metabolic acidosis following rather liberal use of cetrimide-chlorhexidine solution as a scolicidal agent.
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Hepatotoxicity associated with choline magnesium trisalicylate: case report and review of salicylate-induced hepatotoxicity.
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The authors suggest that in patients with corneal ulcers refractory to conventional treatment who are receiving colchicine, cessation of colchicine therapy should be considered.
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Cardiac arrest after esmolol administration: a review of acute beta-blocker toxicity.
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According to the Naranjo et al. adverse-reaction probability scale, enoxaparin was the probable cause of hepatotoxicity in this patient.
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The patient then developed profound bradycardia that progressed to ventricular fibrillation and asystole.
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Response to rhEPO was not significantly related to age, gender, type of MDS, time since diagnosis, time since initiation of transfusion therapy, or baseline serum EPO.
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Somatostatin analogues are safe and generally well tolerated.
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The reactivity of these antibodies, the regulation of the rodent antigens and the identity of the human autoantigen have been investigated.
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DISCUSSION: The main adverse effects of leflunomide consist of diarrhea, nausea, liver enzyme elevation, hypertension, alopecia, and allergic skin reactions.
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Ritonavir acted as a CYP3A4 inhibitor, diminishing carbamazepine metabolism and provoking an increase in serum levels and clinical toxicity.
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CONCLUSION: A scleral abscess should be suspected in a patient with endophthalmitis or microbial keratitis or both after a scleral-tunnel incision for cataract surgery.
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Accordingly, careful monitoring of liver function parameters should be performed both during and after treatment when onychomycosis requires prolonged itraconazole administration, even in asymptomatic patients lacking apparent risk factors of hepatic injury.
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This species is susceptible to many antibiotics in vitro and clinically.
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However, one patient exhibited no effect of PSL and died from acute oliguric renal failure in spite of aggressive measures including hemodialysis.
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Candida shunt infection appears to occur by either contamination at the time of shunt placement or by hematogenous dissemination.
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There is not enough evidence to prove the involvement of either olanzapine or hydrochlorothiazide or the interaction between them in this patient's myelodysplasia.
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Treatment modalities have been unsuccessful and the majority of patients reported have died.
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We propose that drug-induced ocular pemphigoid represents a spectrum of diseases ranging from a self-limiting, toxic form to a progressive, immunologic form.
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None of the patients has clinical or radiologic findings suggestive of central pontine myelinolysis or akinetic mutism.
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Renal biopsy demonstrated changes classic for acute allergic tubulointerstitial nephritis (ATIN), with mixed interstitial inflammatory infiltrate including eosinophils.
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Thirty days after the 2nd booster dose, several pruritic, polygonal, purple, papules appeared on the volar aspect of the patient's wrists.
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After left salpingo-oophorectomy had been performed, the patient chose to terminate the pregnancy before the initiation of combination chemotherapy with bleomycin, etoposide, and cisplatin.
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The contribution of aging, hypothyroidism and stroke to the etiology of this woman's disorder is discussed.
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We describe this syndrome, which occurred in one of our patients and was successfully treated by the administration of dexamethasone.
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The electrocardiogram (ECG), which was read as normal prior to ritodrine infusion, demonstrated a type I second-degree AV block which disappeared upon discontinuation of ritodrine therapy.
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With the increasing use of immunosuppressive agents, including TNF alpha inhibitors, it is likely that there will be an increase in the number of mycobacterial infections complicating arthroplasties.
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We describe a patient who experienced a lichenoid eruption after the initiation of salsalate for relief of arthritic pain.
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Three other patients with clinically determined ULD showed a variable response and some notable side effects during treatment with NAC.
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This report encourages the institution of HAART once the liver graft regains normal function.
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We believe that this represents an unusual case of moderate-dose MTX-induced neurotoxicity in a patient with gastric cancer, which has not previously been reported.
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Only 2 of them developed P. aeruginosa septicemia and the prognosis was relatively good (7.5% mortality rate).
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The patient rejected surgical procedures.
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Even in typical cases PPG is often misdiagnosed and therefore wrongly treated; the unknown aetiology makes treatment difficult.
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Indirect immunofluorescence demonstrated dermal binding IgA antibodies, and Western blotting of serum showed reactivity with a 250 kDa dermal antigen corresponding to collagen VII of anchoring fibrils.
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One patient died suddenly during an exchange with FFP; the cause of death appeared related to microemboli of unknown nature found in the lungs at autopsy.
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Diffuse, reversible arterial irregularities consistent with vasospasm were present on MRA during the acute illness.
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Akathisia should be considered in all cases of apparent nonresponse to atypical antipsychotics.
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