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A possible association between arterial dissection and ergotamine abuse is discussed.
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This phenomenon appears to be related to bilateral simultaneous retinal ischemia delaying regeneration of visual pigments in the pigment epithelial layer.
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This report describes a case of bilateral ptosis induced by chloroquine.
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Dealing with drug-induced thrombocytopenia.
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We report the first case of fulminant adult respiratory distress syndrome (ARDS) associated with pegylated interferon alpha-2a (pegIFNalpha-2a) and ribavirin use for hepatitis C, complicated by subsequent and ultimately fatal sepsis and multiorgan failure.
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Various incidences of hemorrhagic complications have been cited in patients given anticoagulants after stroke or transient cerebral ischemia.
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In this paper, we report a patient with primary anti-phospholipid syndrome treated by corticosteroid, who developed disseminated nocardiosis.
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Pemphigus vulgaris (PV) is a rare but potentially fatal autoimmune bullous disorder which frequently affects the oral mucosa.
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The incidence of primary osteogenic sarcomas of the skull is about 1 to 2% of all skull tumors.
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Environmental interventions are preferred for mild symptoms; medications are the treatment of choice for severe manifestations.
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Laboratory results indicated hypomagnesemia, hypocalcemia, hypokalemia, and hypophosphatemia.
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A 10-year-old boy with osteosarcoma and normal renal function manifested laboratory evidence of impending renal toxicity and extreme elevation of aspartate aminotrasferase and alanine aminotransferase within 2 hours after the completion of a 4-hour infusion of high-dose methotrexate (MTX) (12 g/m2), and went on to develop acute renal failure with life-threatening hyperkalemia 29 hours later.
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Four months after cessation of treatment, a severe acne with comedones, papules, pustules, and small cystic elements broke out.
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Isoniazid was stopped and patient was continued on R & E till completion of the treatment up to nine months.
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The left eye healed with central corneal scarring.
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INTERVENTION: Escalating dose of tissue plasminogen activator infusion.
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Niacin causes a reversible toxic cystoid maculopathy that occurs in approximately 0.67% of patients taking high doses of the drug.
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However, endocrine and clinical responses to chronic treatment have been less consistent.
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Neurological examination revealed atrophy of small hand muscles, especially in the left dorsal interossei.
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The patient whose case is reviewed had migraine headaches and received methysergide maleate for 13 years.
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This has most commonly been a bone complication with little if any soft tissue involvement.
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Here we report on a patient with severe aplastic anemia who developed PRCA after HLA-identical but major ABO-mismatched peripheral blood stem cell transplantation.
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The drug was used topically, by installation and irrigation, in this case and administered orally in doses of up to 1 200 mg daily, for 6 months.
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Four perfusions were performed on patients in stage III, that is those with distant metastases.
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CONCLUSION: A high level of suspicion, prompt antituberculosis treatment and close follow-up are essential in management of post-transplant tuberculosis.
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This report describes a patient who developed spasticity following a traumatic spinal cord injury.
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The patient is alive and free of disease 4 years after the treatment of this second malignant neoplasm (SMN).
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Embolism into the right leg made an embolectomy with a Fogarty catheter necessary.
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Tamoxifen is suggested to be carcinogenic both through direct genotoxic and epigenetic mechanisms.
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Treatment of carbimazole-induced agranulocytosis and sepsis with granulocyte colony stimulating factor.
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However, continued low-dose MTX led, in spite of normal liver tests, 8 years after the last biopsy to liver failure and death in 1 of our patients.
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(3) In 7 of the patients who were treated with EPO before PTX, anemia was improved after PTX despite discontinuation of EPO therapy in 2, a reduced dose of EPO in 3 and the same dose of EPO in 2.
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CONCLUSION: Administration of high-dose intravenous immunoglobulins can be associated with hyperviscosity syndrome manifested by central retinal vein occlusion.
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Affected patients may demonstrate a pattern of self-escalation of dopaminergic medication dosing which may lead to a state of dependency.
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After a second dose of metoclopramide, these symptoms recurred and were associated with confusion, agitation, fever, diaphoresis, tachypnea, tachycardia, and hypertension.
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This case is reported to remind clinicians of the frequent presence of psychiatric symptoms in Sydenham's chorea.
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Complete recovery occurred in all but two patients typically within 1-8 weeks of discontinuation of phenytoin.
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Since the bronchospasm was relieved with discontinuation of propranolol and supportive bronchodilator therapy, the bronchospasm was believed to be caused by propranolol.
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Cranial magnetic resonance imaging showed widespread, abnormally high signal intensity in the deep white matter in both patients, though one patient had normal cranial computed tomographic scan.
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Celiac disease onset after pegylated interferon and ribavirin treatment of chronic hepatitis C.
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Evans syndrome in a patient with chromosome 22q11.2 deletion syndrome: a case report.
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Three patients had a complete remission, five had a partial remission, and four showed no improvements.
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Misdiagnosis in all three patients led to inappropriate topical corticosteroid use.
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A 70-year-old man was admitted to our hospital because of dyspnea after taking an antihistaminic agent (homochlorcyclizine hydrochloride) for itching.
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These symptoms were reproduced after a second administration of brimonidine.
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Opioid use in HIV patients with neurological changes.
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Both the temporal association and pathologic findings suggest that the hyperbaric treatment is likely to have been responsible for the resulting complications.
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RESULTS: A total of 861 patients with ischemic stroke were admitted to Calgary hospitals during the study period.
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A literature review of the relationship between bulimia and affective disorder showed that the evidence from empirical research and case report studies suggests that a sizeable subgroup of bulimics suffer from bipolar disorder as well as bulimia and may benefit from antimanic medications such as lithium.
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CONCLUSION: Physicians should recognise CS-treated patients as a population likely to be immune-suppressed.
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Anterior uveitis and secondary glaucoma resulting from intraocular ointment has not been reported.
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Repeat neuropsychological testing 7 weeks after discontinuation of the drug revealed dramatic improvement in IQ, memory, naming, and other tasks commensurate with clinical recovery in his intellectual capacity.
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It was concluded that ANCA is closely related to the pathogenesis of crescentic glomerulonephritis and that treatment with PTU appeared to induce ANCA.
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Adjustments in his drug regimen led to the discovery of pseudoparkinsonism and other extrapyramidal symptoms.
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Toxoplasmosis retinochoroiditis after photodynamic therapy and intravitreal triamcinolone for a supposed choroidal neovascularization: a case report.
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Rifampin-associated thrombocytopenia secondary to poor compliance.
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Epstein-Barr virus-associated lymphoma in a child undergoing an autologous stem cell rescue.
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This is the first time that the combination of PTX and vit-E has had a significant antifibrotic effect by completely reversing deep RIF as shown by CT scan normalization.
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A 60-year old woman with medullary breast cancer stage IIIB underwent neoadjuvant chemotherapy with TAC (doxetaxele 100 mg/m2, doxorubicin 50 mg/m2 and cyclophosphamide 600 mg/m2).
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His PSA nadir was <0.2 ng/mL and rose slowly over several months to 4.2 ng/mL, resolved, and then rose 2.3 ng/mL before again slowly resolving.
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We present 2 patients with demonstrated IgE-mediated allergy to cloxacillin and tolerance to amoxicillin and cefuroxime.
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In addition, dermal intravascular thrombi resolved.
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Spontaneous compartment syndrome in a patient with diabetes insipidus.
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Alleged medical abandonment in chronic opioid analgesic therapy: case report.
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Herpes simplex following intra-articular sacroiliac corticosteroid injection.
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Patients with lymphoblastic lymphoma who had treatment with L-asparaginase and steroid are predisposed to the development of cortical venous thrombosis and may have this syndrome in addition to a dural puncture headache.
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Dexamethasone elevated markedly the levels of an immunoreactive mouse protein(s) which exhibited a Mr (53 kDa) and inducibility consistent with the major Cyp3a product.
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PURPOSE: To describe the treatment of cytomegalovirus (CMV) retinitis with intravitreal sustain-release ganciclovir devices in a 16-year-old patient in third remission of acute lymphoblastic leukemia after stem cell transplantation.
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Hypoxia is a predisposing factor for premature ductal closure and often occurs after maternal indomethacin therapy.
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CONCLUSIONS: Intravenous followed by intra-arterial therapy is a promising approach to the treatment of severe acute ischemic stroke.
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This case is the eleventh to report this condition.
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One case of ameobic abscess of the liver and one case of amoebic dysentery are described in two patients who were prescribed corticosteroids as part of the intreatment for tuberculous pleural effusion.
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The knowledge concerning VGB-associated visual dysfunction in pediatric patients, particularly in those who have been exposed to VGB in utero is limited.
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A case is described, believed to be the first reported, of a newborn in whom severe hyperreninemic hypertension developed after pyeloplasty of a hydronephrotic kidney.
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Aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension in a patient treated with trimethoprim-sulfamethoxazole.
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Two patients with ovarian cancer who had received multiple courses of cisplatin without complications experienced hypersensitivity reactions to cisplatin: one, involving intrahepatic artery infusion, manifested general erythema, dyspnea, and hypotension; the other, involving intravenous infusion, manifested abdominal pain, general erythema, and fever.
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Specimens of thyroid tissue from two cases with Hashimoto's thyroiditis were immunohistochemically examined for expression of SSTR2A.
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The imaging studies have shown that both hydrocephalus and leukoencephalopathy have improved significantly after ventriculoperitoneal shunt insertion.
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Salicylate-induced hepatotoxicity is reviewed.
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The development of methods to prevent or decrease peritoneal sclerosis will allow for greater application of this innovative therapeutic approach.
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Following 7 days of tigecycline she developed severe abdominal pain and elevated pancreatic enzymes suggesting acute pancreatitis.
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Here we describe a patient with Crohn's disease who developed a severe infliximab infusion reaction (IIR), complicated 1 day later by severe swelling of the forearm and hand ipsilateral to the site of infliximab infusion.
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There was no relation between functional improvement and increased sexuality.
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Three years later, treatment with ampicillin caused another episode of cholestatic hepatitis with cholestasis and duct paucity on rebiopsy.
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CASE: We report a case of a woman with severe human insulin-induced lipoatrophy who has been treated exclusively with recombinant DNA human insulin since the onset of IDDM.
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Two weeks before angioedema, the patient had started a new topical treatment with a gel containing 10% BP for acne.
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A common thread is that they all make some pathophysiologic sense.
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We report a case of generalized cutaneous sclerosis associated with muscle and oesophageal involvement in a patient exposed to herbicides containing bromocil, diuron and aminotriazole.
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The methemoglobinemia was readily reversed with the administration of methylene blue.
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Diagnosis was established by microscopic examination (Gram and Kinyoun) and culture of centrifuged dialysis fluid and the patient was treated with Trimethoprim-Sulfamethoxazole by intraperitoneal route.
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Liver histology showed marked portal inflammation with lymphocytes, monocytes and eosinophils, associated with lobular inflammation (indicative of a histological pattern consistent with drug-induced hepatitis).
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Corneal endothelial deposits associated with rifabutin use.
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A 14-year-old female developed systemic lupus erythematosus (SLE)-like symptoms, rash, fever, leukopenia and positive anti-nuclear antibody (ANA) two weeks after administration of carbamazepine (CBZ; Tegretol) used against benign Rolandic epilepsy.
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Paclitaxel is a chemotherapeutic agent with activity directed against several malignancies.
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A single site of oozing was injected with epinephrine.
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The regimen was based on conditioning experiments with animals who had lupuslike autoimmune disease.
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Hemolytic uremic syndrome (HUS) is a rare complication following solid organ transplantation.
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Therefore, angiotensin-converting enzyme (ACE) inhibitors would appear to be appropriate therapy for hypertension in such patients.
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Cyproterone acetate (CPA) is a widely used drug in the treatment of advanced prostatic carcinoma.
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By searching for the key words AHS, alopecia areata (AA, punctuate absence of terminal scalp hair), AA totalis (complete absence of terminal scalp hair), and AA universalis (total loss of terminal scalp and body hair) using PubMed, only 2 cases, to date, developed alopecia in the convalescent status of phenobarbital-induced AHS.
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