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14021
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2991
[ "APL", "blasts", ",", "available", "only", "from", "patients", "F.R.", "and", "P.G.", ",", "were", "not", "lysed", "by", "C3/5", "and", "were", "unable", "to", "present", "peptide", "BCR1/25", "." ]
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7202
[ "Conversely", ",", "inhibition", "of", "NF-kappaB", "confers", "a", "tenfold", "increase", "in", "glucocorticoid", "mediated", "apoptosis", ",", "establishing", "that", "NF-kappaB", "also", "functions", "as", "an", "antiapoptotic", "factor", "." ]
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7669
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10200
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15687
[ "Direct", "assays", "of", "PKC", "activity", "were", "conducted", "." ]
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16483
[ "Human", "erythroid", "5-aminolevulinate", "synthase", ":", "promoter", "analysis", "and", "identification", "of", "an", "iron-responsive", "element", "in", "the", "mRNA", "." ]
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10918
[ "Finally", ",", "in", "JAK-1-deficient", "HeLa", "cells", ",", "STAT6", "activation", "by", "IL-4", "is", "completely", "abolished", "." ]
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16416
[ "We", "have", "generated", "a", "monoclonal", "antibody", ",", "BZ1", ",", "to", "BZLF1", "which", "reacts", "in", "immunohistology", ",", "immunoblotting", ",", "and", "immunoprecipitation", "and", "which", "recognizes", "both", "the", "active", ",", "dimeric", "form", "and", "the", "inactive", ",", "monomeric", "form", "of", "the", "protein", "." ]
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7348
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8727
[ "Therefore", "we", "investigated", "CTCF", "expression", "and", "phosphorylation", "during", "induced", "differentiation", "of", "human", "myeloid", "leukemia", "cells", "." ]
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2089
[ "Regulation", "of", "interleukin-2", "receptor", "alpha", "chain", "expression", "and", "nuclear", "factor.kappa", "B", "activation", "by", "protein", "kinase", "C", "in", "T", "lymphocytes", "." ]
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17893
[ "OBJECTIVE", ":", "To", "investigate", "the", "long-term", "effects", "of", "treatment", "with", "low", "doses", "of", "flutamide", "on", "clinical", "and", "hormonal", "parameters", ",", "as", "well", "as", "on", "the", "androgen", "receptor", "status", ",", "in", "hirsute", "women", "." ]
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15724
[ "X-linked", "spinal", "and", "bulbar", "muscular", "atrophy", "(", "SBMA", ")", ",", "an", "adult-onset", "form", "of", "motor", "neuron", "disease", ",", "was", "recently", "reported", "to", "be", "caused", "by", "amplification", "of", "the", "CAG", "repeats", "in", "the", "androgen", "receptor", "gene", "." ]
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16399
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10377
[ "Abnormal", "T", "lymphocyte", "development", "induced", "by", "targeted", "overexpression", "of", "IkappaB", "alpha", "." ]
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16998
[ "High", "affinity", "aldosterone", "binding", "sites", "have", "not", "only", "been", "described", "in", "the", "classic", "target", "tissues", "such", "as", "the", "renal", "tubules", ",", "but", "also", "in", "non-classic", "target", "tissues", "such", "as", "the", "hippocampus", ",", "mammary", "gland", ",", "endothelial", "cells", "and", ",", "recently", ",", "human", "mononuclear", "leukocytes", "." ]
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7590
[ "Suppressive", "effects", "of", "anti-inflammatory", "agents", "on", "human", "endothelial", "cell", "activation", "and", "induction", "of", "heat", "shock", "proteins", "." ]
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1746
[ "Not", "only", "do", "these", "positional", "effects", "of", "Nef", "reconcile", "diverse", "phenotypes", "of", "Nef", "and", "suggest", "a", "role", "for", "its", "N-terminal", "myristylation", ",", "but", "they", "also", "explain", "effects", "of", "Nef", "in", "HIV", "infection", "and", "progression", "to", "AIDS", "." ]
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9832
[ "Because", "of", "their", "role", "in", "cell", "adhesion", ",", "PTPase", "may", "provide", "a", "novel", "target", "of", "drug", "development", "for", "treatment", "of", "inflammation", ",", "atherogenesis", ",", "and", "tumor", "metastasis", "." ]
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2031
[ "However", ",", "all", "these", "cell", "types", "still", "gave", "strong", "Ca2+", "and", "tyrosine", "phosphorylation", "responses", "to", "H2O2", "." ]
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2895
[ "Activation", "of", "nuclear", "factor-kappaB", "via", "T", "cell", "receptor", "requires", "a", "Raf", "kinase", "and", "Ca2+", "influx", "." ]
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2896
[ "Functional", "synergy", "between", "Raf", "and", "calcineurin", "." ]
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17057
[ "TPA", "treatment", "of", "HL-60", "cells", "in", "the", "presence", "of", "cycloheximide", "was", "associated", "with", "superinduction", "of", "c-jun", "transcripts", "." ]
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12947
[ "Hormone-induced", "Tax", "activation", "induces", "a", "long-lasting", "activation", "of", "NF-kappaB", ",", "which", "is", "a", "major", "target", "of", "reactive", "oxygen", "intermediates", "." ]
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6505
[ "Here", "we", "investigate", "the", "hypothesis", "that", "low", "shear-induced", "activation", "of", "NF-kappaB", "is", "responsible", "for", "enhanced", "expression", "of", "vascular", "cell", "adhesion", "molecule", "(", "VCAM-1", ")", "resulting", "in", "augmented", "endothelial", "cell-monocyte", "(", "EC-Mn", ")", "adhesion", "and", "that", "this", "activation", "is", "dependent", "on", "intracellular", "oxidant", "activity", "." ]
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15223
[ "In", "the", "case", "of", "HIV-1", ",", "the", "transcription", "factor", "NF-kappa", "B", "is", "sufficient", "for", "inducible", "transcriptional", "activation", "." ]
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5828
[ "In", "this", "report", ",", "we", "use", "the", "PIN*POINT", "assay", "to", "study", "the", "role", "of", "the", "promoter", "on", "the", "recruitment", "of", "EKLF", "to", "5'HS2", "and", "5'HS3", "of", "the", "LCR", "." ]
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15856
[ "Deletion", "mapping", "and", "hybrid", "promoter", "constructs", "demonstrate", "that", "the", "newly", "identified", "Tat-responsive", "element", "corresponds", "to", "a", "sequence", "within", "the", "viral", "long", "terminal", "repeat", "(", "LTR", ")", "previously", "identified", "as", "the", "HIV-1", "enhancer", ",", "or", "NF-kappa", "B", "domain", "." ]
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12908
[ "Transgenic", "mice", "with", "human", "CD3epsilon", "gene", "have", "been", "shown", "to", "exhibit", "early", "arrest", "of", "T", "cell", "development", "in", "the", "thymus", "." ]
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12133
[ "Ciprofibrate", ",", "an", "hypolipidaemic", "peroxisome", "proliferator", ",", "induced", "differentiation", "of", "HL-60", "cells", "." ]
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5208
[ "By", "using", "a", "SOX9", "coding", "sequence", "polymorphism", ",", "expression", "of", "both", "SOX9", "alleles", "has", "been", "demonstrated", "by", "the", "reverse", "transcriptase", "polymerase", "chain", "reaction", "in", "lymphoblastoid", "cells", "from", "one", "of", "the", "translocation", "cases", "." ]
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12359
[ "In", "contrast", ",", "Staurosporine", "prevented", "secretion", "of", "IL-1beta", "by", "unknown", "mechanisms" ]
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14308
[ "To", "examine", "the", "effect", "of", "Trx", "in", "intact", "cells", ",", "we", "performed", "transient", "assay", "with", "a", "chloramphenicol", "acetyltransferase-expressing", "plasmid", "under", "the", "control", "of", "human", "immunodeficiency", "virus", "(", "HIV", ")", "long", "terminal", "repeat", "and", "an", "effector", "plasmid", "expressing", "human", "Trx", "." ]
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6879
[ "Here", "we", "document", "that", "overexpression", "of", "Id3", ",", "in", "progenitors", "that", "have", "initiated", "TCR", "gene", "rearrangements", "(", "pre-T", "cells", ")", ",", "inhibits", "development", "into", "TCRalpha", "beta", "but", "not", "into", "TCRgamma", "delta", "T", "cells", "." ]
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17353
[ "However", ",", "the", "activation", "of", "other", "mitogen-inducible", "transcription", "factors", ",", "such", "as", "Fos", "and", "Jun", ",", "was", "unaffected", "." ]
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15555
[ "The", "use", "of", "interferon-gamma-treated", "U937", "cells", "in", "chemiluminescence", "assays", "to", "detect", "red", "cell", ",", "platelet", "and", "granulocyte", "antibodies", "of", "potential", "clinical", "significance", "." ]
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10068
[ "The", "activation", "of", "the", "JAK2", "/STAT5", "pathway", "is", "commonly", "involved", "in", "signaling", "through", "the", "human", "IL-5", "receptor", "." ]
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13515
[ "However", ",", "Rta", "has", "recently", "been", "reported", "to", "disrupt", "latency", "in", "an", "epithelial", "specific", "manner", "(", "S.", "Zalani", ",", "E.", "Holley-Guthrie", ",", "and", "S.", "Kenney", ",", "Proc.", "Natl.", "Acad.", "Sci.", "USA", "93", ":", "9194-9199", ",", "1996", ")", "." ]
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6714
[ "Of", "even", "more", "interest", ",", "IkappaBalpha", "overexpression", "inhibited", "the", "production", "of", "matrix", "metalloproteinases", "1", "and", "3", "while", "not", "affecting", "their", "tissue", "inhibitor", "." ]
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12329
[ "In", "this", "model", ",", "cells", "cultured", "on", "a", "Silastic", "membrane", "were", "elongated", "up", "to", "7", "%", "of", "their", "initial", "diameter", ",", "corresponding", "to", "a", "12", "%", "increase", "in", "cell", "surface", "." ]
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242
[ "Furthermore", ",", "we", "show", "that", "the", "ICK-1", "binding", "site", "does", "not", "confer", "negative", "regulation", "in", "U937", "cells", "." ]
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