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3401
[ "n-Acetyl-L-cysteine", "(", "NAC", ")", ",", "a", "potent", "antioxidant", ",", "blocked", "NF-kappa", "B", "activation", "caused", "by", "IL-4", "and", "by", "anti-CD40", "mAb", "." ]
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3402
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3403
[ "Second", ",", "we", "studied", "the", "effect", "of", "NAC", "on", "IgE", "synthesis", "in", "human", "normal", "B", "cells", "costimulated", "with", "IL-4", "and", "anti-CD40", "mAb", "." ]
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3404
[ "NAC", "was", "effective", "in", "inhibiting", "mature", "C", "epsilon", "transcription", "and", "IgE", "synthesis", "in", "the", "T", "cell-independent", "culture", "system", "." ]
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3405
[ "However", ",", "NAC", "did", "not", "significantly", "affect", "the", "spontaneous", "production", "of", "IgE", "by", "atopic", "B", "cells", "." ]
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3406
[ "These", "results", "indicate", "that", "NF-kappa", "B", "activity", "is", "commonly", "inducible", "in", "DND39", "cells", "by", "IL-4", "and", "anti-CD40", "mAb", "and", "suggest", "that", "NF-kappa", "B", "sensitive", "to", "NAC", "may", "play", "a", "role", "in", "regulating", "IgE", "synthesis", "in", "B", "cells", "." ]
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3407
[ "Prostaglandin", "E2", "induction", "of", "binding", "activity", "to", "CRE", "and", "AP-2", "elements", "in", "human", "T", "lymphocytes", "." ]
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3408
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3409
[ "Since", "it", "is", "known", "that", "PGE2", "is", "able", "to", "increase", "cAMP", "levels", ",", "we", "investigated", "whether", "it", "can", "affect", "gene", "expression", "through", "the", "activation", "of", "the", "transcription", "factors", "which", "bind", "enhancer", "elements", "in", "the", "promoter", "regions", "of", "cAMP-regulated", "genes", "." ]
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3410
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3411
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3412
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3413
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3414
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3415
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3416
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3417
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3418
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3419
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3420
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3421
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3422
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3423
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3424
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3425
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3426
[ "Potent", "gene", "regulatory", "and", "antiproliferative", "activities", "of", "20-methyl", "analogues", "of", "1", ",", "25", "dihydroxyvitamin", "D3", "." ]
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3427
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3428
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3429
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3430
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3431
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3432
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3433
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3434
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3435
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3436
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3437
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3438
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3439
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3440
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3441
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3442
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3443
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3444
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3445
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3446
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3447
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3448
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3449
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3450
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3453
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