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2401
[ "Arrested", "development", ":", "understanding", "v-abl", "." ]
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2402
[ "The", "protein", "tyrosine", "kinase", "activity", "of", "the", "v-abl", "oncogene", "has", "been", "demonstrated", "to", "subvert", "the", "normal", "second", "messenger", "systems", "used", "by", "lymphoid", "cells", "for", "growth", "and", "differentiation", "." ]
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2403
[ "Transformation", "of", "bone", "marrow", "with", "the", "Abelson", "murine", "leukemia", "virus", "results", "in", "the", "appearance", "of", "B", "cell", "lineage", "cells", "arrested", "at", "the", "pre-B", "cell", "stage", "." ]
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2404
[ "Recent", "reports", "have", "characterized", "these", "cells", "expressing", "high", "v-abl", "kinase", "activity", "as", "deficient", "in", "detectable", "NF-kappaB", "DNA", "binding", "activity", "and", "low", "level", "RAG", "gene", "expression", "." ]
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2405
[ "These", "observations", "suggest", "that", "v-abl", "may", "be", "inhibiting", "the", "differentiation", "of", "B", "cells", "by", "blocking", "these", "two", "crucial", "elements", "in", "the", "maturation", "pathway", "." ]
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2406
[ "Corticosteroid", "receptors", "in", "lymphocytes", ":", "a", "possible", "marker", "of", "brain", "involution", "?" ]
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2407
[ "A", "similarity", "has", "recently", "been", "found", "between", "the", "regulation", "of", "corticosteroid", "receptors", "in", "brain", "and", "in", "lymphoid", "tissue", "." ]
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2408
[ "We", "have", "studied", "the", "regulation", "of", "corticosteroid", "receptors", "in", "human", "mononuclear", "leukocytes", "as", "a", "possible", "marker", "of", "brain", "involution", "." ]
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2409
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2410
[ "In", "normal", "adults", "there", "is", "a", "direct", "significant", "correlation", "between", "plasma", "cortisol", "and", "Type", "I", "and", "between", "plasma", "cortisol", "and", "Type", "II", "receptors", "in", "mononuclear", "leukocytes", ",", "while", "in", "Cushing", "'s", "syndrome", "the", "correlation", "is", "inverse", "between", "plasma", "cortisol", "at", "8", "a.m.", "and", "Type", "II", "receptors", "." ]
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2411
[ "In", "an", "aged", "population", "the", "mean", "numbers", "of", "Type", "I", "and", "of", "Type", "II", "receptors", "are", "lower", "and", "plasma", "cortisol", "is", "higher", "than", "in", "adult", "controls", ",", "but", "the", "increase", "of", "plasma", "cortisol", "is", "not", "followed", "by", "a", "clinical", "picture", "of", "hypercorticism", "." ]
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2412
[ "Corticosteroid", "Type", "I", "and", "Type", "II", "receptors", "are", "inversely", "correlated", "with", "age", "." ]
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2413
[ "After", "dexamethasone", "suppression", "(", "1", "mg", "at", "11", "p.m.", ")", "Type", "I", "receptors", "always", "decrease", "in", "controls", "while", "the", "response", "of", "Type", "II", "is", "not", "homogeneous", "." ]
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2414
[ "In", "an", "aged", "group", "of", "patients", ",", "both", "receptors", "are", "reduced", "by", "dexamethasone", "." ]
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2415
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2416
[ "All-trans", "retinoic", "acid", "and", "1", "alpha", ",", "25-dihydroxyvitamin", "D3", "co-operate", "to", "promote", "differentiation", "of", "the", "human", "promyeloid", "leukemia", "cell", "line", "HL60", "to", "monocytes", "." ]
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2417
[ "A", "basis", "for", "differentiation", "therapy", "of", "leukemias", "is", "provided", "by", "knowledge", "of", "agents", "which", "induce", "specific", "lineage", "maturation", "." ]
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2418
[ "All-trans", "retinoic", "acid", "(", "RA", ")", "induces", "differentiation", "of", "HL60", "cells", "to", "neutrophils", "and", "is", "used", "to", "treat", "acute", "promyelocytic", "leukemia", "." ]
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2419
[ "We", "observed", "that", "RA", "did", "not", "induced", "neutrophil", "differentiation", "in", "serum-free", "grown", "HL60", "cells", "whereas", "50", "nM", "1", "alpha", ",", "25-dihydroxyvitamin", "D3", "(", "D3", ")", "induced", "maximal", "monocyte", "differentiation", "." ]
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2420
[ "Increasing", "RA", "concentrations", "reduced", "the", "D3", "concentration", "required", "for", "monocyte", "differentiation", "." ]
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2421
[ "Cells", "treated", "with", "5", "nM", "D3", "showed", "little", "response", ",", "but", "differentiated", "maximally", "with", "5", "nM", "D3", "and", "10", "nM", "RA", "." ]
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2422
[ "The", "D3", "analogs", "MC903", ",", "EB1089", "and", "KH1060", "were", "more", "potent", "inducers", "of", "monocyte", "differentiation", "." ]
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2423
[ "The", "extent", "to", "which", "analog", "activity", "was", "increased", "after", "cotreatment", "with", "RA", "was", "inversely", "related", "to", "potency", "." ]
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2424
[ "Twenty-four", "hour", "treatment", "with", "10", "nM", "RA", "primed", "cells", "for", "response", "to", "5", "nM", "D3", ";", "the", "reverse", "sequence", "being", "ineffective", "." ]
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2425
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2426
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2427
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2428
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2429
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2430
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2431
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2432
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2433
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2434
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2435
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2436
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2437
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2438
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2440
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2441
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2446
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2470
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2473
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2476
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2479
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2480
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2481
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2482
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2483
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2494
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2496
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