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We report 3 cases of HIV-1 infected patients who experienced symptomatic angiolipomas shortly after starting antiretroviral therapy including the protease inhibitor indinavir. | [
{
"ade": "angiolipomas",
"drug": "indinavir"
}
]
|
46-year-old woman developed painful ulcers over her lower abdomen in the form of reticulate erythema after injecting interferon beta-1b subcutaneously for multiple sclerosis. | [
{
"ade": "reticulate erythema",
"drug": "interferon beta-1b"
},
{
"ade": "painful ulcers",
"drug": "interferon beta-1b"
}
]
|
Acute leukaemia during tamoxifen therapy. | [
{
"ade": "Acute leukaemia",
"drug": "tamoxifen"
}
]
|
We describe the clinical and liver biopsy morphologic features for 4 patients with minocycline-induced autoimmune hepatitis (group 1). | [
{
"ade": "autoimmune hepatitis",
"drug": "minocycline"
}
]
|
Our findings reveal that even in patients without a history of seizures, pregabalin can cause a cortical negative myoclonus. | [
{
"ade": "cortical negative myoclonus",
"drug": "pregabalin"
}
]
|
RESULTS: All cases developed corneal endothelial deposits after previous use of rifabutin. | [
{
"ade": "corneal endothelial deposits",
"drug": "rifabutin"
}
]
|
Gastric tumor, endometrial carcinoma and cervical adenocarcinoma in situ were detected after treatment with tamoxifen for breast cancer. | [
{
"ade": "Gastric tumor",
"drug": "tamoxifen"
},
{
"ade": "endometrial carcinoma",
"drug": "tamoxifen"
},
{
"ade": "cervical adenocarcinoma",
"drug": "tamoxifen"
}
]
|
Docetaxel-induced Meibomian duct inflammation and blockage leading to chalazion formation. | [
{
"ade": "chalazion",
"drug": "Docetaxel"
},
{
"ade": "Meibomian duct inflammation and blockage",
"drug": "Docetaxel"
}
]
|
After treatment with cimetidine, there was a rapid deterioration with decreased oxygen saturation and arterial PO2 values. | [
{
"ade": "decreased oxygen saturation and arterial PO2",
"drug": "cimetidine"
}
]
|
The development of cutaneous ecchymosis associated with a sudden fall in hemoglobin after the administration of alteplase should strongly suggest the possibility of diffuse subfascial hematoma. | [
{
"ade": "diffuse subfascial hematoma",
"drug": "alteplase"
},
{
"ade": "cutaneous ecchymosis",
"drug": "alteplase"
},
{
"ade": "sudden fall in hemoglobin",
"drug": "alteplase"
}
]
|
Ophthalmologists should be aware of the ocular side effects of IFN therapy and carefully monitor patients for the possible occurrence of hypoalbuminemia and thrombocytopenia. | [
{
"ade": "thrombocytopenia",
"drug": "IFN"
},
{
"ade": "hypoalbuminemia",
"drug": "IFN"
},
{
"ade": "ocular side effects",
"drug": "IFN"
}
]
|
We report the case of a 51-year-old man in whom IFN-alpha treatment was followed by recurrence of Graves' disease 10 years after thyroidectomy was performed and the patient was declared cured. | [
{
"ade": "Graves' disease",
"drug": "IFN-alpha"
}
]
|
We report a case of acute hyperphosphatemia secondary to rectal administration of sodium phosphate and sodium biphosphate (Fleet enema). | [
{
"ade": "hyperphosphatemia",
"drug": "sodium phosphate"
},
{
"ade": "hyperphosphatemia",
"drug": "sodium biphosphate"
}
]
|
Adrenal suppression in a fetus due to administration of methylprednisolone has hitherto been rarely published. | [
{
"ade": "Adrenal suppression in a fetus",
"drug": "methylprednisolone"
}
]
|
We report here a case of TEN after administration of ciprofloxacin. | [
{
"ade": "TEN",
"drug": "ciprofloxacin"
}
]
|
A diagnosis of infliximab-induced lupus was made and the drug treatment was withdrawn. | [
{
"ade": "lupus",
"drug": "infliximab"
}
]
|
Physicians using this "new" drug must be aware of the potential danger of sulfonamide-induced injury to the urinary tract. | [
{
"ade": "injury to the urinary tract",
"drug": "sulfonamide"
}
]
|
Well-differentiated endometrial adenocarcinoma of the secretory type (FIGO Grade 1) with minimal myometrial invasion occurred in a postmenopausal patient on tamoxifen therapy 5 years after mastectomy for breast carcinoma. | [
{
"ade": "endometrial adenocarcinoma of the secretory type",
"drug": "tamoxifen"
}
]
|
Retrospectively, bucillamine was believed to be the cause of the giant hypertrophy because of its structural similarity to D-penicillamine, which was the subject of an abundance of reports of mammary hyperplasia. | [
{
"ade": "mammary hyperplasia",
"drug": "D-penicillamine"
},
{
"ade": "giant hypertrophy",
"drug": "bucillamine"
}
]
|
OBJECTIVE: To report the late development of immune-mediated diabetes mellitus after completion of alfa-interferon therapy for hepatitis C in an Asian patient. | [
{
"ade": "immune-mediated diabetes mellitus",
"drug": "alfa-interferon"
}
]
|
Recurrent septicemia with lethal outcome during and after cyclosporine therapy in severe ulcerative colitis. | [
{
"ade": "lethal",
"drug": "cyclosporine"
},
{
"ade": "septicemia",
"drug": "cyclosporine"
}
]
|
Interstitial pneumonitis associated with sirolimus: a dilemma for lung transplantation. | [
{
"ade": "Interstitial pneumonitis",
"drug": "sirolimus"
}
]
|
A 35-year-old man with seropositive rheumatoid arthritis developed selective IgA deficiency during treatment with fenclofenac. | [
{
"ade": "IgA deficiency",
"drug": "fenclofenac"
}
]
|
Adverse effects of amiodarone including pulmonary toxicity, hepatotoxicity, aggravation of arrhythmia, and thyroid diseases are well understood. | [
{
"ade": "hepatotoxicity",
"drug": "amiodarone"
},
{
"ade": "aggravation of arrhythmia",
"drug": "amiodarone"
},
{
"ade": "pulmonary toxicity",
"drug": "amiodarone"
},
{
"ade": "thyroid diseases",
"drug": "amiodarone"
}
]
|
Morphea after bromocriptine therapy. | [
{
"ade": "Morphea",
"drug": "bromocriptine"
}
]
|
METHODS: A 68-year-old man developed intense conjunctival hyperemia and cystoid macula edema after switching from latanoprost to bimatoprost 9 months after cataract surgery in an eye at low-risk for this cystoid macular edema. | [
{
"ade": "intense conjunctival hyperemia",
"drug": "bimatoprost"
},
{
"ade": "cystoid macula edema",
"drug": "bimatoprost"
},
{
"ade": "cystoid macula edema",
"drug": "latanoprost"
},
{
"ade": "intense conjunctival hyperemia",
"drug": "latanoprost"
},
{
"ade": "cystoid macular edema",
"drug": "bimatoprost"
},
{
"ade": "cystoid macular edema",
"drug": "latanoprost"
}
]
|
CASE SUMMARY: A 25-year-old postpartum white woman developed multiple watery stools and abdominal cramping on day 6 of therapy with clindamycin vaginal cream for bacterial vaginosis. | [
{
"ade": "multiple watery stools",
"drug": "clindamycin"
},
{
"ade": "abdominal cramping",
"drug": "clindamycin"
}
]
|
Hydroxyurea-induced acute interstitial pneumonitis in a patient with essential thrombocythemia. | [
{
"ade": "acute interstitial pneumonitis",
"drug": "Hydroxyurea"
}
]
|
Hydroxyurea (HU) and sodium phenylbutyrate (SPB) have been shown to increase fetal hemoglobin (Hb F) levels in patients with thalassemia intermedia. | [
{
"ade": "increase fetal hemoglobin",
"drug": "sodium phenylbutyrate"
},
{
"ade": "increase fetal hemoglobin",
"drug": "Hydroxyurea"
}
]
|
CONCLUSION: Lipoid pneumonia as a result of mineral oil aspiration still occurs in the pediatric population. | [
{
"ade": "Lipoid pneumonia",
"drug": "mineral oil"
}
]
|
Prominent eye movements during NREM sleep and REM sleep behavior disorder associated with fluoxetine treatment of depression and obsessive-compulsive disorder. | [
{
"ade": "REM sleep behavior disorder",
"drug": "fluoxetine"
},
{
"ade": "Prominent eye movements during NREM sleep",
"drug": "fluoxetine"
}
]
|
Interaction between tacrolimus and nefazodone in a stable renal transplant recipient. | [
{
"ade": "Interaction",
"drug": "tacrolimus"
},
{
"ade": "Interaction",
"drug": "nefazodone"
}
]
|
Bone formation induced in an infant by systemic prostaglandin-E2 administration. | [
{
"ade": "Bone formation",
"drug": "prostaglandin-E2"
}
]
|
Insulin-induced lipoatrophy in type I diabetes. | [
{
"ade": "lipoatrophy",
"drug": "Insulin"
}
]
|
Acute myocardial infarction due to coronary spasm associated with L-thyroxine therapy. | [
{
"ade": "Acute myocardial infarction",
"drug": "L-thyroxine"
},
{
"ade": "coronary spasm",
"drug": "L-thyroxine"
}
]
|
We also describe a new, noninvasive method to assess magnesium-induced neuromuscular block when curariform muscle relaxant was given simultaneously. | [
{
"ade": "neuromuscular block",
"drug": "magnesium"
}
]
|
Four cases of oesophageal damage associated with ingestion of the urinary anti-spasmodic agent emepronium bromide are described. | [
{
"ade": "oesophageal damage",
"drug": "emepronium bromide"
}
]
|
CASES: Two postmenopausal women treated with tamoxifen and progestational agents for breast carcinoma developed uterine enlargement and intermittent spotting. | [
{
"ade": "uterine enlargement",
"drug": "tamoxifen"
},
{
"ade": "intermittent spotting",
"drug": "tamoxifen"
}
]
|
Three patients with niacin-induced visual symptoms had cystoid maculopathy without leakage on fluorescein angiography, and a fourth patient with no fundus abnormality experienced cessation of visual symptoms upon discontinuation of niacin. | [
{
"ade": "cystoid maculopathy",
"drug": "niacin"
},
{
"ade": "visual symptoms",
"drug": "niacin"
}
]
|
The second had acute cystitis and was treated by sulphonamide and the third developed myopia coincident with metronidazole treatment for trichomonas vaginalis. | [
{
"ade": "myopia",
"drug": "sulphonamide"
},
{
"ade": "myopia",
"drug": "metronidazole"
}
]
|
To our knowledge, this is the first case report that demonstrates the occurrence of fever with low-dose amifostine therapy without the manifestation of accompanying rash or hypotension. | [
{
"ade": "fever",
"drug": "amifostine"
}
]
|
Fixed drug eruption to rofecoxib. | [
{
"ade": "Fixed drug eruption",
"drug": "rofecoxib"
}
]
|
Rapamycin/sirolimus-induced pneumonitis has been described previously in renal transplant recipients, and this report describes a stable heart-lung transplant recipient who developed a pulmonary infiltrate that reversed after ceasing SR therapy. | [
{
"ade": "pulmonary infiltrate",
"drug": "Rapamycin"
},
{
"ade": "pulmonary infiltrate",
"drug": "SR"
},
{
"ade": "pulmonary infiltrate",
"drug": "sirolimus"
},
{
"ade": "pneumonitis",
"drug": "Rapamycin"
},
{
"ade": "pneumonitis",
"drug": "sirolimus"
}
]
|
A small initial dose of prazosin ranging from 0.5 to 1 mg has been recommended to avoid the first-dose phenomenon characterized by a sudden and severe drop in blood pressure after the administration of the first dose of prazosin. | [
{
"ade": "severe drop in blood pressure",
"drug": "prazosin"
}
]
|
Kaposi's sarcoma in a patient treated with imatinib mesylate for chronic myeloid leukemia. | [
{
"ade": "Kaposi's sarcoma",
"drug": "imatinib mesylate"
}
]
|
Halothane hepatitis and prompt resolution with methionine therapy: case report. | [
{
"ade": "hepatitis",
"drug": "Halothane"
}
]
|
An insulin-dependent diabetic patient with nephropathy developed severe acidosis after treatment with acetazolamide for glaucoma. | [
{
"ade": "severe acidosis",
"drug": "acetazolamide"
}
]
|
Diagnosis of hypothyroidism during treatment can be difficult because of the common side effects of alpha interferon. | [
{
"ade": "hypothyroidism",
"drug": "alpha interferon"
}
]
|
The reported cases of in utero exposure to cyclosposphamide shared the following manifestations with our patient: growth deficiency, developmental delay, craniosynostosis, blepharophimosis, flat nasal bridge, abnormal ears, and distal limb defects including hypoplastic thumbs and oligodactyly. | [
{
"ade": "flat nasal bridge",
"drug": "cyclosposphamide"
},
{
"ade": "distal limb defects",
"drug": "cyclosposphamide"
},
{
"ade": "hypoplastic thumbs",
"drug": "cyclosposphamide"
},
{
"ade": "craniosynostosis",
"drug": "cyclosposphamide"
},
{
"ade": "developmental delay",
"drug": "cyclosposphamide"
},
{
"ade": "blepharophimosis",
"drug": "cyclosposphamide"
},
{
"ade": "oligodactyly",
"drug": "cyclosposphamide"
}
]
|
In conclusion, this case strongly suggests that gliclazide can induce acute icteric liver necro-inflammation which may be misdiagnosed clinically as acute viral hepatitis. | [
{
"ade": "acute icteric liver necro-inflammation",
"drug": "gliclazide"
}
]
|
However, peripheral neuropathy and bone marrow depression led to linezolid withdrawal in seven patients, and neuropathy may not be fully reversible in all patients. | [
{
"ade": "neuropathy",
"drug": "linezolid"
},
{
"ade": "peripheral neuropathy",
"drug": "linezolid"
},
{
"ade": "bone marrow depression",
"drug": "linezolid"
}
]
|
Does the use of insulin in a patient with liver dysfunction increase water retention in the body, i.e. cause insulin oedema? | [
{
"ade": "oedema",
"drug": "insulin"
}
]
|
A 16-year-old white male with acute biphenotypic leukemia developed evidence of the eosinophilia myalgia syndrome associated with total parenteral nutritional support with solutions containing tryptophan, which were given during his initial induction chemotherapy and also after autologous marrow transplantation. | [
{
"ade": "eosinophilia myalgia syndrome",
"drug": "tryptophan"
}
]
|
We describe a relatively healthy, 9-year-old boy who developed a CA-MRSA skin and soft tissue infection and was treated with TMP-SMX. | [
{
"ade": "soft tissue infection",
"drug": "TMP-SMX"
}
]
|
Colchicine-induced rhabdomyolysis. | [
{
"ade": "rhabdomyolysis",
"drug": "Colchicine"
}
]
|
FK506, which began to be administered 12 days earlier, rose to a level of 44 ng/mL (normal range, 10-20 ng/mL) 1 day before neurologic abnormalities began. | [
{
"ade": "neurologic abnormalities",
"drug": "FK506"
}
]
|
In these patients, long-acting octreotide may trigger serious hypoglycemia. | [
{
"ade": "serious hypoglycemia",
"drug": "octreotide"
}
]
|
The first patient was a 61-year-old man with a 30-year history of fistulizing CD in whom B-cell non-Hodgkin's lymphoma was diagnosed 9 months after treatment with infliximab. | [
{
"ade": "B-cell non-Hodgkin's lymphoma",
"drug": "infliximab"
}
]
|
Upper gastrointestinal haemorrhage is a serious complication of aspirin and clopidogrel (dual) anti-platelet therapy with a high morbidity and mortality. | [
{
"ade": "Upper gastrointestinal haemorrhage",
"drug": "aspirin"
},
{
"ade": "Upper gastrointestinal haemorrhage",
"drug": "clopidogrel"
}
]
|
Occasionally, despite good therapeutic response, clozapine must be stopped due to dangerous side effects such as agranulocytosis. | [
{
"ade": "agranulocytosis",
"drug": "clozapine"
}
]
|
This concerns 2 male patients who experienced incontinence while taking venlafaxine. | [
{
"ade": "incontinence",
"drug": "venlafaxine"
}
]
|
Following the institution of intravenous therapy with acyclovir, the patient developed fever, hemoptysis, and a pleural friction rub. | [
{
"ade": "pleural friction rub",
"drug": "acyclovir"
},
{
"ade": "fever",
"drug": "acyclovir"
},
{
"ade": "hemoptysis",
"drug": "acyclovir"
}
]
|
Although a lot of amiodarone-induced torsades de pointe have been published, a review of all these cases and the underlying risk-factors has never been made. | [
{
"ade": "torsades de pointe",
"drug": "amiodarone"
}
]
|
Four Chinese female patients who suffered from manic-depressive disorder and underlying autoimmune thyroiditis developed transient episodes of thyrotoxicosis during maintenance lithium therapy. | [
{
"ade": "thyrotoxicosis",
"drug": "lithium"
}
]
|
Gynaecomastia is a rarely reported adverse drug reaction due to isoniazid therapy. | [
{
"ade": "Gynaecomastia",
"drug": "isoniazid"
}
]
|
An obese patient, not diabetic, treated with metformin for some weeks, was referred to us with severe inferior digestive hemorrhage, diagnosed with Meckel's diverticulum. | [
{
"ade": "severe inferior digestive hemorrhage",
"drug": "metformin"
}
]
|
A case report of the hypersensitivity syndrome occurring in a patient being treated with dapsone for a brown recluse spider bite is presented. | [
{
"ade": "hypersensitivity syndrome",
"drug": "dapsone"
}
]
|
Central nervous system manifestations of an ibuprofen overdose reversed by naloxone. | [
{
"ade": "Central nervous system manifestations",
"drug": "ibuprofen"
}
]
|
Three of these patients had convulsions attributed to imipenem/cilastatin; 3.6% of the patients had seizure, or 2% of imipenem/cilastatin administrations was followed by a seizure attack. | [
{
"ade": "seizure",
"drug": "imipenem"
},
{
"ade": "convulsions",
"drug": "cilastatin"
},
{
"ade": "seizure",
"drug": "cilastatin"
},
{
"ade": "convulsions",
"drug": "imipenem"
}
]
|
A 59-year-old woman with myasthenia gravis who received a large dose of pyridostigmine bromide developed postoperative psychosis and was diagnosed as having bromide intoxication. | [
{
"ade": "bromide intoxication",
"drug": "pyridostigmine bromide"
},
{
"ade": "postoperative psychosis",
"drug": "pyridostigmine bromide"
}
]
|
Although there is one case report of cholesterol crystal embolization following t-PA therapy with only extrarenal manifestations (N Engl J Med 321:1270, 1989), this is the first reported case of atheroembolic acute renal failure following t-PA therapy. | [
{
"ade": "cholesterol crystal embolization",
"drug": "t-PA"
},
{
"ade": "atheroembolic acute renal failure",
"drug": "t-PA"
},
{
"ade": "extrarenal manifestations",
"drug": "t-PA"
}
]
|
One patient who received clindamycin had liver biopsy findings of marked cholestasis, portal inflammation, bile duct injury and bile duct paucity (ductopenia). | [
{
"ade": "marked cholestasis",
"drug": "clindamycin"
},
{
"ade": "bile duct paucity",
"drug": "clindamycin"
},
{
"ade": "bile duct injury",
"drug": "clindamycin"
},
{
"ade": "portal inflammation",
"drug": "clindamycin"
},
{
"ade": "ductopenia",
"drug": "clindamycin"
}
]
|
A patient with acute changes suggesting acute hepatitis after parenteral amiodarone administration is described. | [
{
"ade": "acute hepatitis",
"drug": "amiodarone"
}
]
|
Fatal interstitial lung disease after erlotinib administration in a patient with radiation fibrosis. | [
{
"ade": "Fatal interstitial lung disease",
"drug": "erlotinib"
}
]
|
He became hyperkalemic on rechallenge with timolol and normokalemic following its withdrawal. | [
{
"ade": "hyperkalemic",
"drug": "timolol"
}
]
|
Although they had only a few nodules at diagnosis, the nodules increased in number and size 3 to 4 months after the start of methotrexate therapy in both patients. | [
{
"ade": "nodules",
"drug": "methotrexate"
}
]
|
CASE SUMMARY: An 80-year-old white female, followed up at the Memory Clinic for mild cognitive impairment, had been taking propafenone 900 mg/d for >10 years for paroxysmal atrial fibrillation without adverse effects. | [
{
"ade": "mild cognitive impairment",
"drug": "propafenone"
}
]
|
CONCLUSIONS: The piloerection observed after the replacement of fluvoxamine with milnacipran in this patient appears to have been due to an increase in the alpha(1)-adrenoceptor occupancy by endogenous norepinephrine induced by milnacipran. | [
{
"ade": "piloerection",
"drug": "fluvoxamine"
},
{
"ade": "piloerection",
"drug": "milnacipran"
}
]
|
Recently, her serum theophylline levels had increased to the toxic range (133.2 micromol/L [24 microg/mL]) shortly after the addition of zafirlukast (Accolate, Zeneca Pharmaceuticals, Wilmington, Del) to her regimen. | [
{
"ade": "theophylline levels had increased to the toxic range",
"drug": "theophylline"
},
{
"ade": "theophylline levels had increased to the toxic range",
"drug": "Accolate"
},
{
"ade": "theophylline levels had increased to the toxic range",
"drug": "zafirlukast"
}
]
|
Three cases of acute renal toxicity in patients receiving long-term therapy with mitomycin C and 5-fluorouracil are reported. | [
{
"ade": "acute renal toxicity",
"drug": "5-fluorouracil"
},
{
"ade": "acute renal toxicity",
"drug": "mitomycin C"
}
]
|
Lichenoid drug eruption to salsalate. | [
{
"ade": "Lichenoid drug eruption",
"drug": "salsalate"
}
]
|
CONCLUSION: A 37-year-old African- American man with G6PD deficiency developed hemolytic anemia, hepatitis, orthostatic hypotension, and aseptic meningitis simultaneously after using trimethoprim-sulfamethoxazole. | [
{
"ade": "hemolytic anemia",
"drug": "sulfamethoxazole"
},
{
"ade": "orthostatic hypotension",
"drug": "trimethoprim"
},
{
"ade": "hepatitis",
"drug": "sulfamethoxazole"
},
{
"ade": "aseptic meningitis",
"drug": "sulfamethoxazole"
},
{
"ade": "hepatitis",
"drug": "trimethoprim"
},
{
"ade": "orthostatic hypotension",
"drug": "sulfamethoxazole"
},
{
"ade": "hemolytic anemia",
"drug": "trimethoprim"
},
{
"ade": "aseptic meningitis",
"drug": "trimethoprim"
}
]
|
We present three cases from the Provincial Toxicology Center of British Columbia, Canada in which suicidal overdose deaths were associated with quetiapine. | [
{
"ade": "suicidal overdose deaths",
"drug": "quetiapine"
}
]
|
A 14-year-old female developed systemic lupus erythematosus (SLE)-like symptoms, rash, fever, leukopenia and positive anti-nuclear antibody (ANA) two weeks after administration of carbamazepine (CBZ; Tegretol) used against benign Rolandic epilepsy. | [
{
"ade": "systemic lupus erythematosus (SLE)-like symptoms",
"drug": "Tegretol"
},
{
"ade": "leukopenia",
"drug": "Tegretol"
},
{
"ade": "systemic lupus erythematosus (SLE)-like symptoms",
"drug": "carbamazepine"
},
{
"ade": "fever",
"drug": "CBZ"
},
{
"ade": "leukopenia",
"drug": "carbamazepine"
},
{
"ade": "rash",
"drug": "CBZ"
},
{
"ade": "positive anti-nuclear antibody",
"drug": "CBZ"
},
{
"ade": "leukopenia",
"drug": "CBZ"
},
{
"ade": "systemic lupus erythematosus (SLE)-like symptoms",
"drug": "CBZ"
},
{
"ade": "fever",
"drug": "Tegretol"
},
{
"ade": "rash",
"drug": "carbamazepine"
},
{
"ade": "rash",
"drug": "Tegretol"
},
{
"ade": "fever",
"drug": "carbamazepine"
},
{
"ade": "positive anti-nuclear antibody",
"drug": "carbamazepine"
},
{
"ade": "positive anti-nuclear antibody",
"drug": "Tegretol"
}
]
|
The hyperpigmentation was diffuse scattered, flagellate like and linear streaking which was thought to be mainly related to the skin toxicity of bleomycin. | [
{
"ade": "skin toxicity",
"drug": "bleomycin"
}
]
|
This case highlights the possible development of acute coronary syndrome as a side effect of Capecitabine therapy. | [
{
"ade": "acute coronary syndrome",
"drug": "Capecitabine"
}
]
|
Pulmonary toxicity secondary to procarbazine. | [
{
"ade": "Pulmonary toxicity",
"drug": "procarbazine"
}
]
|
Therefore, parenteral amiodarone was implicated as the cause of acute hepatitis in this patient. | [
{
"ade": "acute hepatitis",
"drug": "amiodarone"
}
]
|
Renal failure associated with the use of dextran-40. | [
{
"ade": "Renal failure",
"drug": "dextran-40"
}
]
|
Myasthenia gravis during low-dose IFN-alpha therapy for chronic hepatitis C. | [
{
"ade": "Myasthenia gravis",
"drug": "IFN-alpha"
}
]
|
Potential causes of methamphetamine-related keratitis can be divided into four categories resulting from (a) direct pharmacologic and physical effects of methamphetamine; (b) the toxic effects of diluting or "cutting" agents such as lidocaine and quinine; (c) effects related to the route of drug administration (intravenous, inhalation, smoking); and (d) manufacture-related effects of exposure to unintentional caustic contaminants in the final product. | [
{
"ade": "keratitis",
"drug": "methamphetamine"
},
{
"ade": "toxic effects",
"drug": "methamphetamine"
},
{
"ade": "toxic effects",
"drug": "lidocaine"
},
{
"ade": "keratitis",
"drug": "lidocaine"
},
{
"ade": "keratitis",
"drug": "quinine"
},
{
"ade": "toxic effects",
"drug": "quinine"
}
]
|
Danazol induced thrombocytopenia. | [
{
"ade": "thrombocytopenia",
"drug": "Danazol"
}
]
|
A case of metoclopramide-induced oculogyric crisis in a 16-year-old girl with cystic fibrosis. | [
{
"ade": "oculogyric crisis",
"drug": "metoclopramide"
}
]
|
We report for the first time the development of symptomatic methemoglobinemia after an acute ingestion of divalproex sodium (Depakote), resulting in serum concentrations 10 times greater than the therapeutic range. | [
{
"ade": "symptomatic methemoglobinemia",
"drug": "divalproex sodium"
},
{
"ade": "symptomatic methemoglobinemia",
"drug": "Depakote"
}
]
|
Statin-associated myasthenia gravis: report of 4 cases and review of the literature. | [
{
"ade": "myasthenia gravis",
"drug": "Statin"
}
]
|
An 11-day-old infant became lethargic and apneic after a single drop of brimonidine. | [
{
"ade": "apneic",
"drug": "brimonidine"
},
{
"ade": "lethargic",
"drug": "brimonidine"
}
]
|
Our case is the second one in which hemorrhage from a meningioma may have been induced by aspirin prophylaxis. | [
{
"ade": "hemorrhage",
"drug": "aspirin"
}
]
|
Hypokalemia after normal doses of neubulized albuterol (salbutamol). | [
{
"ade": "Hypokalemia",
"drug": "salbutamol"
},
{
"ade": "Hypokalemia",
"drug": "albuterol"
}
]
|
Adriamycin-induced cardiomyopathy aggravated by cis-platinum nephrotoxicity requiring dialysis. | [
{
"ade": "cardiomyopathy",
"drug": "Adriamycin"
},
{
"ade": "nephrotoxicity",
"drug": "cis-platinum"
}
]
|
We describe a patient with metastatic prostate cancer who developed nonoliguric renal failure during treatment with suramin. | [
{
"ade": "nonoliguric renal failure",
"drug": "suramin"
}
]
|
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