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First Samurai First Samurai is a thoroughbred race horse born February 2, 2003. He was a contender for the Triple Crown in 2006, but after a starting gate incident contributed to his defeat in the Toyota Blue Grass Stakes he was ruled unlikely to race in the Kentucky Derby. Two weeks after the race, First Samurai was diagnosed with two broken ribs following an ultrasound. He was not entered in the Kentucky Derby, with his injury cited as the reason. The Blue Grass ultimately proved to be his final race. Connections First Samurai is owned by Bruce Lunsford Tom Hansen, Tom Morris & Raymond Coudriet and is trained by Frank Brothers. He has been ridden by Pat Day and Jerry Bailey, both jockeys now retired, and the still racing Edgar Prado. First Samurai was bred in Kentucky by John D. Gunther. Races In his career, cut short by injury, he started 8 times, winning 5, placing in 1, showing in 1, with total earnings of $915,075 Stud career First Samurai stands at stud at the Hancock Family's Claiborne Farm near Paris, Kentucky. His starting fee in 2007 was $40,000 and stood alongside Claiborne's other stallions, which included Pulpit, Seeking the Gold, During, Eddington, and Strong Hope. First Samurai's descendants include: c = colt, f = filly Pedigree References First Samurai's pedigree National Thoroughbred Racing Association bio Category:2003 racehorse births Category:Racehorses trained in the United States Category:Racehorses bred in Kentucky Category:Thoroughbred family 13 | High | [
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Controversial preacher James Ng'ang'a of Neno Evangelism Ministries has claimed he is rich enough to buy vehicles at will. Ng'ang'a who was preaching to a congregation in his church said he was the best and most blessed preacher in the country with the ability to buy vehicles and exchange them like pairs of shoes. READ ALSO: Ex-Bomet governor Isaac Ruto says William Ruto doesn't owe Uhuru any loyalty Controversial preacher James Ng'ang'a has bragged he buys cars like shoes. Photo: Nation Source: Facebook READ ALSO: Francis Kimanzi ateuliwa rasmi kuwa kocha mkuu wa Harambee Stars In a video clip that surfaced on Tuesday, August 20, the boastful preacher dismissed claims he was using his position as a church leader to swindle the congregation and amass wealth. "I buy vehicles like shoes, I buy vehicles when I want and don't tell it is because of the church. If that is the case you can go and open yours too. Do all pastors buy vehicles that way? Those are blessings from God," he told his congregation READ ALSO: Cristiano Ronaldo leaves his 9-year-old son astonished after visiting his origin Ng'ang'a said the fact that he is the most talked about preacher in the country is testimony he is the best evangelist. He left his followers giggling after claiming he was also the most handsome man of God and people have openly expressed that to him. " They talk negative things about me and I am not bothered because it gives me publicity. Some meet me and say ooh this is the famous Ng'ang'a, he is such a handsome guy," he said amid cheers Controversial preacher James Ng'ang'a has bragged how he buys cars like shoes. Photo: Nation Source: Facebook READ ALSO: Pastor James Ng’ang’a arrested for threatening top journalist with unspecified consequences The preacher told his congregation God had risen him from a prisoner to a powerful preacher in the country with a huge following. " I was released from prison in 1992 and I was given a mkokoteni (hand cart) which I used to carry luggage for people as I preached. I was later gifted a bicycle which I used to move from one point to another preaching the gospel," recalled Ng'ang'a He also disclosed he used to sell newspapers to generate income for his upkeep and preaching activities. The Neno Evangelism preacher said he was gifted the first car by one of his church members who later took it back after he had just repaired and re-branded it. Ng'ang'a told the church he bought his own car later on by making a mere deposit of KSh 10, 000 out of the agreed price of KSh 380, 000. Since then, the preacher claimed God has been faithful to him and he can now afford to buy vehicles at will. He recently angered Kenyans after humiliating two women in his church over their perceived cheap dressing code. Ng'ang'a summoned one of the ladies on the pulpit and abused her after he discovered she had put on cheap rubber shoes and carried her stuff in a small bag. He was also on the spot for publicly telling off senior leaders in his church whom he refereed to as "rubbish" and "arrogant" for allegedly disrespecting his wife. One of the bishops quit in a huff following the public humiliation. Do you have a groundbreaking story you would like us to publish? Please reach us through [email protected] or WhatsApp: 0732482690. Contact Tuko.co.ke instantly. I am saved - Stivo Simple Boy I Tuko TV | Low | [
0.5059101654846331,
26.75,
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Driver detection of water quality trends in three large European river basins. This study analyses how indicators of water quality (thirteen physico-chemical variables) and drivers of change (i.e., monthly aggregated air temperature and streamflow, population density, and percentage of agricultural land use) coevolve in three large European river basins (i.e., Adige, Ebro, Sava) with different climatic, soil and water use conditions. Spearman rank correlation, Principal Component Analysis, and Mann-Kendall trend tests were applied to long-term time series of water quality data during the period 1990-2015 in order to investigate the relationships between water quality parameters and the main factors controlling them. Results show that air temperature, considered as a proxy of climatic change, has a significant impact, in particular in the Adige and Ebro: positive trends of water temperature and negative of dissolved oxygen are correlated with upward trends of air temperatures. The aquatic ecosystems of these rivers are, therefore, experiencing a reduction in oxygen, which may exacerbate in the future given the projected further increase in temperature. Furthermore, monthly streamflow has been shown to reduce in the Ebro, thereby reducing the beneficial effect of dilution, which appears evident from the observed upward patterns of chloride concentrations and electrical conductivity. Upward trends of chloride and biological oxygen demand in the Adige and Sava, and of phosphate in the Adige appears to be related to increasing human population density, whereas phosphates in the Sava and biological oxygen demand in the Ebro are highly correlated with agricultural land use, considered as a proxy of the impact of agricultural practises. The present study shows the complex relationships between drivers and observed changes in water quality parameters. Such analysis can represent, complementary to a deep knowledge of the investigated systems, a reliable tool for decision makers in river basin planning by providing an overview of the potential impacts on the aquatic ecosystem of the three basins. | Mid | [
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/** * JBZoo Application * * This file is part of the JBZoo CCK package. * For the full copyright and license information, please view the LICENSE * file that was distributed with this source code. * * @package Application * @license GPL-2.0 * @copyright Copyright (C) JBZoo.com, All rights reserved. * @link https://github.com/JBZoo/JBZoo */ ; (function ($, window, document, undefined) { jQuery(function ($) { var joomlaVersion = JBZoo.getVar('joomlaVersion', '3'); // Menu tabs hack $('li[data-href-replace]').each(function (n, obj) { var $obj = $(obj), replace = $(obj).data('href-replace'), $link = $obj.children('a'), href = $link.attr('href'); if (replace) { $link.attr('href', href.replace(replace, 'controller=item')); } }); // init Joomla CP Scripts $('#menu').JBZooAdminMenu(JBZoo.getVar('JBAdminItems', {'items': {}})); // fix for print version $('.jbzoo .uk-grid').closest('html').addClass('jbzoo-print'); // fix for modules $('#module-form').addClass('jbzoo'); // hack add parent class for admin panel $('body').addClass('jbzoo-joomla-' + joomlaVersion); if ($("#nav [data-jbzooversion].active").length) { $('<span class="version" />') .text("JBZoo " + $("#nav [data-jbzooversion].active").data("jbzooversion")) .appendTo("#nav div.bar"); } // some plugins $.fn.JBZooKeyValue(); $.fn.JBZooJKeyValue(); $.fn.JBZooItemOrder(); // wrapper for all select with chosen $('.jbzoo select').JBZooSelect(); }); })(jQuery, window, document); | Mid | [
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Yesterday, a story began circulating on social media about a cosplayer at San Diego Comic Con who was in the hospital after being discovered on the side of the road, bloody and unconscious. The story was reported on a few blogs, most notably Graphic Policy and The Beat, mainly citing a Tumblr post calling for information about the incident and quoting a plea for help from a parent of the girl in question. Here's the Tumblr post, with names removed because the girl is a minor and deserves (and is legally entitled to) her privacy: One of my dearest friends was found on the side of the road, unconscious and bloody. She was wearing this cosplay on the day it happened. She was last seen with friends when she ran off after a disagreement. Please, please, please, if you have ANY information or saw her anywhere, contact her mother. The full information is down below. This isn’t okay and it’s sickening to know that this happened at a place people truly can enjoy themselves. Please spread the word. ”I just received a call from the San Diego Police Department and my daughter REDACTED aka REDACTED was found on the side of the road covered in blood with no ID unconscious. They are unsure what happened to her. My husband is on his way to the police station and then the hospital. If you have any information on what happened to her please send me a facebook message or call me at REDACTED. Thank you in advance”. -REDACTED The coverage of this story was widespread, and yet scarce on details. Thanks to the contact information in that original message, repeated and linked to in blogs and tweets, anyone interested could easily read the cosplayer's Facebook page and the pages of both her parents, but very few details about what actually happened were available. Some of the blogs and tweets (many from some big names), while of course well-meaning, included pictures and the real name of this girl, though it should be noted that The Beat's article redacted all names and images from the start. Discussions included a lot of back and forth on whether this was "a hoax," with confused attempts to contact first the San Diego Police Department and then the San Diego Harbor Police, both of whom, at first, claimed no knowledge of the incident. I understand the desire to give this story a signal boost. Coming off the high of a very long weekend of celebrating comics and geek culture, to have a member of our community attacked in such a senseless, violent way is shocking. It makes you want to do something - anything - to help, and the angle of the story seemed to be "help the police find information on this attack." As i turns out, they already had a suspect in custody. The San Diego Harbor Police sent out a press release last night to the blogs inquiring about the incident: Harbor Police arrested a 29-year-old man early Sunday morning, July 27th in a hotel at 333 West Harbor Drive. He was booked into San Diego County Jail at 11:20 am on charges of sexual contact with a minor and contributing to the delinquency of minor. The victim, a juvenile female, was transported to a hospital for evaluation and treatment. The Harbor Police Investigations Unit is handling the incident. This investigation is ongoing. I can imagine how you feel right now, reading this. Furious. Depressed. Shocked. Confused. Disappointed. I wish I could offer you something to make that better in some way, but I can't. I feel the same way you do. None of that, however, can possibly compare to the way this girl and her family must feel. The all-too-personal narrative I read earlier while investigating are stuck in my mind. A young woman excited to be going to Comic Con, posting pictures of her costume. Proud parents directing friends and family to check out their daughter's public cosplay page. And then this. If we learn of a way that we can direct our readers to help without invading this family's privacy any further, we'll let you know. Until then, just be kind to your fellow geeks, and to all people. UPDATE: There has been an update on this story from the police. The injuries to the cosplayer are now suspected to be from a fall, though this does not affect the charges against the man. Read more about it here. Comment without an Outhouse Account using Facebook We get it. You don't feel like signing up for an Outhouse account, even though it's FREE and EASY! That's okay. You can comment with your Facebook account below and we'll take care of adding it to the stream above. But you really should consider getting a full Outhouse account, which will allow you to quote posts, choose an avatar and sig, and comment on our forums too. If that sounds good to you, sign up for an Outhouse account by clicking here. Note: while you are welcome to speak your mind freely on any topic, we do ask that you keep discussion civil between each other. Nasty personal attacks against other commenters is strongly discouraged. Thanks! Help spread the word, loyal readers! Share this story on social media: About the Author - Jude Terror Jude Terror is the Webmaster Supreme of The Outhouse and a sarcastic ace reporter dedicated to delivering irreverent comics and entertainment news to The Outhouse's dozens of loyal readers. Driven by a quest for vengeance, Jude Terror taught himself to program and joined The Outhouse. He instantly began working toward his goal of forcing the internet comics community to take itself less seriously and failing miserably. A certified trash eater ruining the pristine field of comics journalism with his sarcasm and goofiness, Jude Terror is secretly friendly and congenial, so if you've got a complaint, why not just bring it up to him instead of subtweeting like a jackass, jackass? You can find him on Twitter or try your luck with an email, but keep in mind that he is notoriously unreliable and may not get back to you right away. Unless you want to send him free stuff, in which case he'll get back to you immediately. | Mid | [
0.605316973415132,
37,
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Q: Switch on Array type Overview I would like to use switch statement by matching array type. I have the following classes. Class: class A {} class B : A {} Switch on single value works: let a : A = B() switch a { case let b as B: print("b = \(b)") default: print("unknown type") } Switch on array (Compilation Error): let aArray : [A] = [B(), B()] switch aArray { case let bArray as [B] : print("bArray = \(bArray)") default: print("unknown type") } Error: Downcast pattern value of type '[B]' cannot be used Note: Tested on Swift 4 Question: How can I achieve this ? A: In Swift 4.1, you get a better error message (thanks to #11441): Collection downcast in cast pattern is not implemented; use an explicit downcast to '[B]' instead In short, you're hitting a bit of the compiler that isn't fully implemented yet, the progress of which is tracked by the bug SR-5671. You can however workaround this limitation by coercing to Any before performing the cast: class A {} class B : A {} let aArray : [A] = [B(), B()] switch aArray /* or you could say 'as Any' here depending on the other cases */ { case let (bArray as [B]) as Any: print("bArray = \(bArray)") default: print("unknown type") } // bArray = [B, B] Why does this work? Well first, a bit of background. Arrays, dictionaries and sets are treated specially by Swift's casting mechanism – despite being generic types (which are invariant by default), Swift allows you to cast between collections of different element types (see this Q&A for more info). The functions that implement these conversions reside in the standard library (for example, Array's implementation is here). At compile time, Swift will try to identify collection downcasts (e.g [A] to [B] in your example) so it can directly call the aforementioned conversion functions, and avoid having to do a full dynamic cast through the Swift runtime. However the problem is that this specialised logic isn't implemented for collection downcasting patterns (such as in your example), so the compiler emits an error. By first coercing to Any, we force Swift to perform a fully dynamic cast, which dispatches through the runtime, which will eventually wind up calling the aforementioned conversion functions. Although why the compiler can't temporarily treat such casts as fully dynamic casts until the necessary specialised logic is in place, I'm not too sure. | Mid | [
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Illegal immigrants tell a local news reporter they came to the United States because they saw advertisements online, in newspapers and on TV talking about the loads of free handouts that await them in the United States. “They say if we come to the United States we can find work,” one man tells KGBT CBS4 reporter Sydney Hernandez, who recently witnessed close to 300 illegals cross the border in a single night. “Yes,” another illegal confirms, “we’ve been told that, we read it on our newspapers. That’s why we’re here.” Hernandez says every illegal immigrant she interviewed says they came to the US “because free American services and assistance are being advertised in their home countries.” Mirror 1 & 2: If you are wondering why so many people think they will get free shit when they cross the border, watch this video. If you are wondering who is buying all this advertising of free shit … #SOROS 🤡🌏 pic.twitter.com/fwyNJIGI9F — Rob Dew (@DewsNewz) July 15, 2019 Watch: “I am Antifa” Terrorist Hoped ICE Attack Would Trigger Bloody Civil War The Emergency Election Sale is now live! Get 30% to 60% off our most popular products today! | Low | [
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Complementary therapy use among HIV-infected patients. This study investigates factors associated with the self-reported use of complementary therapies, types of therapies used, and sources of complementary therapy information among HIV-positive patients attending a public, HIV outpatient clinic in New Orleans. A convenience sample of 287 clients (220 men and 67 women) was given a self-administered anonymous questionnaire. Overall, complementary therapy use was 31%. Patients who used complementary therapy were more likely to be white (O.R., 2.5), female (O.R. 3.3), a high school graduate (O.R. 2.9), and to know another complementary therapy user (O.R. 7.8). Age, sexual orientation, CD4 cell count, injection drug use, living with another HIV-infected person, having pain, and HIV support group membership were not associated. Men were more likely than women, and whites were more likely than nonwhites, to use vitamins/minerals, imagery/meditation, and dietary regimens. Nonwhites were more likely than whites, and women more likely than men, to use spiritual healing. Of those using complementary therapy, men were more likely than women, and whites more likely than nonwhites, to get information about complementary therapy from HIV organizations, friends, and homosexual-oriented media. Doctors and nurses were the most frequently cited source of complementary therapy information for women. Frequency, type of therapies used, and source of information about complementary therapy among HIV-infected persons vary by race and gender. Clinicians should be educated about complementary therapies so that they can provide information to their patients and be aware of self-treatment behavior. | Mid | [
0.6390804597701151,
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] |
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings. Myasthenia gravis: a clinical-immunological update. Binks S., Vincent A., Palace J. Myasthenia gravis (MG) is the archetypic disorder of both the neuromuscular junction and autoantibody-mediated disease. In most patients, IgG1-dominant antibodies to acetylcholine receptors cause fatigable weakness of skeletal muscles. In the rest, a variable proportion possesses antibodies to muscle-specific tyrosine kinase while the remainder of seronegative MG is being explained through cell-based assays using a receptor-clustering technique and, to a lesser extent, proposed new antigenic targets. The incidence and prevalence of MG are increasing, particularly in the elderly. New treatments are being developed, and results from the randomised controlled trial of thymectomy in non-thymomatous MG, due for release in early 2016, will be of particular clinical value. To help navigate an evidence base of varying quality, practising clinicians may consult new MG guidelines in the fields of pregnancy, ocular and generalised MG (GMG). This review focuses on updates in epidemiology, immunology, therapeutic and clinical aspects of GMG in adults. | Mid | [
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Fairfax, Va. - Today, Secretary of State John Kerry signed the United Nations Arms Trade Treaty on behalf of the Obama administration. The National Rifle Association strongly opposes this treaty, which is a clear violation of the Second Amendment to the U.S. Constitution. "The Obama administration is once again demonstrating its contempt for our fundamental, individual Right to Keep and Bear Arms," said Chris W. Cox, executive director of the NRA's Institute for Legislative Action. "This treaty threatens individual firearm ownership with an invasive registration scheme. The NRA will continue working with the United States Senate to oppose ratification of the ATT." A bipartisan majority of the U.S. Senate is already on record in opposition to ratification of the ATT. On March 23, the Senate adopted an amendment to its FY 2014 Budget Resolution, offered by Sen. James Inhofe (R-OK), that establishes a deficit-neutral fund for "the purpose of preventing the United States from entering into the United Nations Arms Trade Treaty." This amendment is in addition to the previous efforts of Sen. Jerry Moran (R-KS) and Rep. Mike Kelly (R-PA) to pass concurrent resolutions opposing the treaty in their respective chambers. Notably, the ATT includes "small arms and light weapons" within its scope, which covers firearms owned by law-abiding citizens. Further, the treaty urges recordkeeping of end users, directing importing countries to provide information to an exporting country regarding arms transfers, including "end use or end user documentation" for a "minimum of ten years." Each country is to "take measures, pursuant to its national laws, to regulate brokering taking place under its jurisdiction for conventional arms." Data kept on the end users of imported firearms is a de-facto registry of law-abiding firearms owners, which is a violation of federal law. Even worse, the ATT could be construed to require such a registry to be made available to foreign governments. "These are blatant attacks on the constitutional rights and liberties of every law-abiding American. The NRA will continue to fight this assault on our fundamental freedom," concluded Cox. -NRA- Established in 1871, the National Rifle Association is America's oldest civil rights and sportsmen's group. More than four million members strong, NRA continues to uphold the Second Amendment and advocates enforcement of existing laws against violent offenders to reduce crime. The Association remains the nation's leader in firearm education and training for law-abiding gun owners, law enforcement and the armed services. Be sure to follow the NRA on Facebook at www.facebook.com/NationalRifleAssociation and on Twitter @NRA. | Mid | [
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using NUnit.Framework;
using OpenWrap.Commands.Errors;
using OpenWrap.Commands.Remote;
using OpenWrap.Testing;
using Tests.Commands.contexts;
namespace Tests.Commands.remote{}
namespace Tests.Commands.remote.remove
{
public class removing_unknown : remote_command<RemoveRemoteCommand>
{
public removing_unknown()
{
when_executing_command("esgaroth");
}
[Test]
public void an_error_is_returned()
{
Results.ShouldHaveOne<UnknownRemoteName>()
.Name.ShouldBe("esgaroth");
}
}
} | Mid | [
0.580722891566265,
30.125,
21.75
] |
Jared Allen blasts NFL decision on Looney hit The NFL ruled on Tuesday that Joe Looney's hit on Vikings defensive tackle Kevin Williams was legal and that the San Francisco backup lineman won't be punished. Vikings defensive end Jared Allen became irate when informed of that news after practice. "That's absurd to me," he said. "That's absolutely absurd. He had a perfect opportunity to hit him in the chest. He could have taken that block up high. But he intentionally went to his knee. We want to talk about protecting player safety and all that stuff. If he hits Kevin in the chest and something happens, that's part of it. But when you intentionally duck and go to a guy's knee? You talk about player safety and wanting to protect us, how is Kevin not a defenseless player? So for me that's absolutely absurd. It's just not what you do." Allen believes the league has a double standard and that a defensive player would have been fined if the roles were reversed. "If a defensive player would have hit an offensive lineman in the knee like that on an interception, they're going to call it, right?" he said. "Just because he wasn't going back toward his own end zone they say it's not the peel-back rule. But the intent was to take his knee out. He could have hit him right in the chest and no one would have said anything. But when you intentionally duck and put your helmet or put your shoulder pad into a guy's knee, in my place there's no room for that." "I have a problem when we talk about player safety in this league and we have a clear case of a guy intentionally trying to hurt a guy and we do nothing about and we pat him on the back and say it's OK," Allen said. "It's bad enough we have to deal with an offensive lineman can engage us and an adjacent offensive lineman can chop our legs," Allen said. "It's bad enough that we have to deal with a motioning tight end coming in in a pass rush situation. We're focused on the tackle and they can take our ears out. I'm just saying, be consistent. How was [Williams] not a defensive player? You go back and look at that play and you tell me he's not a defenseless player. He has no idea that that guy is there and the dude could have taken him up high. He could have taken him in the chest and he chose to duck down and hit him in his knee. Yeah, you can say I'm a little upset about it." "If you get hurt in the course of a game and it's a block, it happens. But to intentionally take someone's knee out is just dirty." Allen was fined $21,000 last season after hitting Chicago's Lance Louis during an interception return. Allen's blindside hit resulted in Louis tearing his ACL. "They said I launched into him," Allen said. "I didn't go in their with the intent of taking his knee out. Imagine what the fine wouild have been if I would have knifed his knee. I got fined something hefty because they said I launched. They said he was a defenseless player. I took it. But I had no ill intent. My problem with this play is the intent. He ducked down to hit him in the knee. If the league can't see that, they can fine me for this. It's absurd." Matt Vensel is in his first year at the Star Tribune after covering the Ravens for the Baltimore Sun for six years. He is a Pittsburgh native and a Penn State grad. Follow him at @mattvensel. Mark Craig has covered the NFL for 23 years, and the Vikings since 2003 for the Star Tribune. He is one of 44 Pro Football Hall of Fame selectors. Follow him at @markcraignfl. Master Tesfatsion is the Star Tribune’s digital Vikings writer. He is a 2013 graduate of Arizona State and worked for mlb.com before arriving in Minneapolis. Follow him at @masterstrib. | Mid | [
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LEHIGH VALLEY INSITE Lehigh Valley InSite is a blog about things to do, see and experience in Eastern Pennsylvania’s Lehigh Valley. Whether you live here or are coming for a visit, this blog can be your official source for activities, attractions and events. The authors of Lehigh Valley InSite, who live and work in the region, are staff members of Discover Lehigh Valley, the official destination marketing organization for Lehigh and Northampton counties. The authors are not compensated or otherwise influenced by the businesses or events they write about. On occasion, freelance bloggers are invited to share their experiences from a different perspective. Discover Lehigh Valley is proud to partner with the Greater Lehigh Valley Music Association to sponsor the Discovered Artist Award. Each year, this award spotlights those who are either new to the scene or who had a breakout year in recognition. Don't let winter fade away without enjoying some seasonal activities! Lehigh Valley certainly looks stunning under a blanket of fresh, white snow - as seen in these #LiftYourSpiritsDLV photos on Instagram. Be sure to make time to explore before the spring thaw sets in! Categories: Tags: Bear Creek Mountain Resort is a Pennsylvania destination resort without the drive. The resort offers hotel packages and year-round activities of family fun for everyone. With winter in full swing, make your way to Bear Creek and be sure to check out these seasonal favorites. Categories: Tags: Sometimes, it's not about the journey or the destination but the company you keep on your adventures. However, a trip along the Lehigh Valley Covered Bridge Tour with that special someone could give you both! Categories: Tags: Create new memories with family and friends at Blue Mountain Resort this winter. Celebrating their 40th anniversary season, there are a variety of events and packages to help guests enjoy the winter weather, have some fun, and create memories that will last a lifetime. Categories: Tags: Grab your hot cocoa and scarves and check out these holiday favorites in Lehigh Valley. Whether you prefer to take in the spectacular light displays by foot or from the comfort of a heated vehicle, you're sure to be astounded by these displays. Who knows - you might even spot Santa for a photo opportunity! | Mid | [
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Asthma Asthma (from a Greek word which means “panting”) is a chronic airway disorder that is sometimes fatal and can cause significant impairment of daily life. It is characterized by variable and recurring symptoms which are mostly caused by reversible airflow obstruction and bronchospasm. The explanation for this is simple, the lungs are connected to the outside via bronchi, these are hollow pipelike organs so it isn’t difficult to imagine what will happen if these were to be blocked in any way.Asthma (from a Greek word which means “panting”) is a chronic airway disorder that is sometimes fatal and can cause significant impairment of daily life. It is characterized by variable and recurring symptoms which are mostly caused by reversible airflow obstruction and bronchospasm. The explanation for this is simple, the lungs are connected to the outside via bronchi, these are hollow pipelike organs so it isn’t difficult to imagine what will happen if these were to be blocked in any way.Asthma can be caused by several factors. These are usually a combination of complex and incompletely understood environmental and genetic interactions. These factors influence both its severity and its responsiveness to the treatment. It is believed that the recent increased rates of asthma are due to changing epigenetics (heritable factors other than those related to the DNA sequence) and a changing living environment. So one might argue that the causes of asthma are related to both nature and nurture.Asthma is clinically classified according to the frequency of symptoms, forced expiratory volume in one second (FEV), and peak expiratory rate. These last two are tests that could be carried out in hospitals by spirometry. Asthma may also be classified as atopic (extrinsic) or non-atopic (intrinsic), based on whether symptoms are precipitated by allergens (atopic) or not (non-atopic). While asthma is classified based on severity, at moment there is no clear method for classifying different subgroups of asthma beyond this system. Finding ways to identify subgroups that respond well to different types of treatments is a current critical goal of asthma research. Some of the signs and symptoms of Asthma are recurrent episodes of wheezing, shortness of breath, chest tightness and coughing. Sputum may be produced in the bronchioles during an asthma attack but is often hard to cough up. This sputum may appear pus-like due to high levels of white blood cells called eosinophils. Symptoms are usually worse at night and in early mornings or in the response to exercise or cold air. Some people with asthma rarely experience symptoms, usually in response to triggers, whereas others may have marked and persistent symptoms. Associated conditions include a number of other health conditions that occur more frequently in asthmatics. These include gastro-esophageal reflux disease (GERD) and obstructive sleep apnea. Psychological disorders are also common, with anxiety disorders occurring between 16-52% and mood disorders in 14-41%. However, it is not known if asthma causes psychological problems or if psychological problems lead to asthma. I personally find this statement very funny and I know you do too. Many environmental factors have been associated with asthma’s development and exacerbation. These include allergens (Any substance that can cause an allergy or a hypersensitivity reaction), air pollution, and other environmental chemicals. It has also been found that smoking during pregnancy and after delivery is associated with greater risk of asthma-like symptoms. Low air quality from factors such as traffic pollution or high ozone levels has been associated with both asthma development and asthma severity. Exposure to indoor volatile organic compounds may be a trigger for asthma; things like formaldehyde exposure, for example, has a positive association. Asthma is associated with exposure to indoor allergens. Common indoor allergens include: dust mites, cockroaches, animal dander, and mold. Efforts to decrease dust mites have been found to be ineffective so giving your room a good clean every once in a while can help decrease the frequency of attacks. Certain viral respiratory infections such as respiratory syncytial virus and rhinovirus (commonly called common cold, no pun intended) may increase the risk of developing asthma when acquired as young children. Certain other infections, however, may decrease the risk. Some individuals will have stable asthma for weeks or months and then suddenly develop an episode of acute asthma. Different individuals react to various factors in different ways. Most individuals can develop severe exacerbation from a number of triggering agents. Home factors that can lead to exacerbation of asthma include dust, animal dander (especially cat and dog hair), cockroach allergens and mold. Perfumes are a common cause of acute attacks in women and children. Both viral and bacterial infections of the upper respiratory tract can worsen the disease. Psychological stress may worsen symptoms-it is thought that stress alters the immune system and thus increases the airway inflammatory response to allergens and irritants.The hygiene hypothesis attempts to explain the increased rates of asthma worldwide as a direct and unintended result of reduced exposure, during childhood, to non-pathogenic bacteria and viruses. It has been proposed that the reduced exposure to bacteria endotoxin in early childhood may prevent the development of asthma, but exposure at an older age may provoke bronchoconstriction. Bronchoconstriction is when the airways become smaller and this makes the breathing more difficult. Evidence supporting the hygiene hypothesis includes lower rates of asthma on farms and in households with pets.Having a close relative with asthma is a significant risk factor, with many different genes being implicated. If one identical twin is affected, the probability of the other having the disease is approximately 25%. Some genetics variants may only cause asthma when they are combined with specific environmental exposures.There is a correlation between obesity and the risk of asthma with both having increased in recent years in our Gambian society. Several factors may be at play including decreased respiratory function due to a buildup of fat and the fact that the adipose tissue leads to a pro-inflammatory state. Beta blocker medications such as propranolol can trigger asthma in those who are susceptible. Cardio selective beta blockers, however, appear safe in those with mild or moderate disease. Other medications that can cause problems are NSAIDs (like aspirin, ibuprofen) and angiotensin-converting enzyme inhibitors like captopril.The evidence for the effectiveness of measures to prevent the development of asthma is weak. Some including: limiting smoke exposure both in utero and after delivery, and breastfeeding. While there is no cure for asthma, symptoms can typically be improved. A specific, customized plan for proactively monitoring and managing symptoms should be created. This plan should include the reduction of exposure to allergens, testing to assess the severity of symptoms, and the usage of medications. The treatment plan should be written down and advise adjustments to treatment according to changes in symptoms.Medications used to treat asthma are divided into two general classes: quick relief medications used to treat acute symptoms; and long-term control medications used to prevent further exacerbation. Fast-acting· Short-acting beta-adrenoceptor agonists (SABA), such as salbutamol(albuterol USAN) are the first line treatment for asthma treatment. They are recommended before exercise in those with exercise induced symptoms.· Anticholinergic medications, such as ipratropium bromide provide benefit when used in combination with SABA in those with moderate or severe symptoms.Long-term control· Corticosteroids are generally considered the most effective treatment available for long-term control.· Long-acting beta-adrenoceptor agonists (LABA) such as salmeterol and formoterol can improve asthma control, at least in adults, when given in combinations with inhaled corticosteroids.· Leukotriene antagonists may be used in addition to inhaled corticosteroids, typically also in conjunction with LABA· Mast cell stabilizers are another non-preferred alternative to corticosteroids. Consult your doctor or any heath personnel about a plan of action for acute asthma attacks. Act when your chest feels tight and your reliever inhaler doesn’t help quickly enough. Know when it’s time to grab your bagpack bag and head for hospital – if you wait too long it could cost you your life. | Mid | [
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Introduction {#s1} ============ Despite aggressive surgery, radiation, and chemotherapy, gliomas remain virtually incurable, with median overall survival of patients with glioblastoma, the most common type of malignant glioma in adults, still measured only in terms of months ([@B1]--[@B3]). The blood-brain barrier (BBB) imposes a major limitation on the delivery of anti-cancer drugs to treat glioma. Glioma cells disseminate from the primary site to form micro-tumor foci throughout the brain, which often "hide behind" the BBB, through which most chemotherapy agents cannot pass ([@B4]). The diffuse and highly infiltrative nature of glioma cells further impedes the success of treating gliomas, as no clear border exists between tumor and normal brain tissue, rendering surgical cures elusive. Human neural stem cell (NSC)-based therapies have emerged as promising strategies for the treatment of central nervous system (CNS) diseases and injury ([@B5]--[@B8]). Most current clinical trials aim to use NSCs for regenerative purposes: to replace damaged tissue, stimulate repair, or restore missing enzymes. Our NSC-based anti-cancer strategy, however, harnesses the intrinsic tumor-tropic properties of NSCs ([@B9]--[@B15]), which permit their use as delivery vehicles to selectively target therapeutic gene products to invasive brain tumor cells ([@B16]). By modifying NSCs to express a prodrug-converting enzyme, we can potentially produce higher concentrations of chemotherapy drugs directly at tumor sites while minimizing toxicity to normal regions of the brain ([@B17]--[@B21]). We demonstrated the safety of a first-generation NSC-mediated gene therapy that utilized a clonal human NSC line genetically modified to express cytosine deaminase (HB1.F3.CD21; CD-NSCs) in a first-in-human study for recurrent glioma patients ([@B19], [@B21]). Cytosine deaminase is an enzyme that converts the orally administered prodrug fluorocytosine (5-FC) to the chemotherapy agent 5-fluorouracil (5-FU). Results from our study included initial demonstration of safety, non-immunogenicity, and proof-of-concept for brain tumor-localized NSC-mediated 5-FU production ([@B21]). We also developed a second-generation NSC-mediated enzyme/prodrug gene therapy by adenovirally transducing CD-NSCs to transiently secrete a highly active modified form of human carboxylesterase (hCE1m6) ([@B22]). Carboxylesterase (CE) converts the chemotherapy drug irinotecan (IRN) to the 1,000× more potent topoisomerase-1 inhibitor SN-38. We demonstrated that the CE-secreting NSCs (CE-NSCs) are 70-fold more efficient at converting IRN to SN-38 compared to endogenous hCE1 (\<5% conversion in the liver and intestines) ([@B23]--[@B25]). Intravenously administered IRN has only modest anti-tumor activity in patients with high-grade gliomas ([@B26]--[@B28]), likely due to poor CNS penetration of its 1,000-fold more active form, SN-38. Our preclinical data in mice bearing orthotopic human glioma demonstrated that after intracerebral/tumoral (ICT) administration, CE-NSCs migrate to distant tumor sites in the contralateral brain ([@B4], [@B13]). *In vivo* pharmacology studies revealed CE-NSC mediated conversion of IRN to SN-38, resulting in concentrations of SN-38 at the tumor site that are 8--10 times higher than concentrations after treatment with IRN alone ([@B22]). Treatment with CE-NSCs and IRN significantly extended the survival of human glioma-bearing mice relative to treatment with IRN alone or no treatment ([@B17]). Based on these preclinical data, a phase 1 study (clinicaltrials.gov ID **NCT02192359**) is being conducted at City of Hope in patients with recurrent high-grade gliomas using ICT administration to determine the safety and feasibility of ICT administration of CE-NSCs via a Rickham reservoir/catheter system every 2 weeks, followed by intravenous IRN 2 days later. IVEN delivery offers five major advantages over ICT delivery: (1) the ability to dose escalate NSCs beyond volume restrictions for ICT administration; (2) improved NSC viability in cerebrospinal fluid (CSF) vs. the hostile environment of the resection cavity; (3) no intratumorally placed catheter tips around which gliosis and scar formation may occur to restrict NSC migration; (4) improved feasibility of performing multi-center studies due to general familiarity with placing Ommaya reservoirs IVEN and using them to administer chemotherapy intrathecally; and (5) potential for CE-NSC mediated gene therapy for treating leptomeningeal metastases from primary and metastatic brain tumors. In this report, we demonstrate that after **intracerebral/ventricular (IVEN)** administration, therapeutic CE-NSCs can migrate to tumors in the brains of mice in three different glioma models: (1) U251 glioma-bearing tumors, (2) patient-derived glioma xenografts (PDXs), and (3) mouse GL261 glioma model ([Figure 1](#F1){ref-type="fig"}). Our data demonstrates the distribution of the CE-NSCs to multiple orthotopic glioma sites in mice following **IVEN administration** ([Figure 1](#F1){ref-type="fig"}). {#F1} Materials and Methods {#s2} ===================== Cell Culture ------------ For all studies, we used the v-*myc*-immortalized, human clonal HB1.F3.CD21 NSC line, which is genetically and functionally stable, non-tumorigenic, and minimally immunogenic ([@B19], [@B29], [@B30]). Briefly, NSCs were thawed and cultured in Dulbecco\'s modified Eagle\'s medium (DMEM) supplemented with 10% heat-inactivated fetal bovine serum and 2 mM L-glutamine for 3 days (37°C, 6% CO~2~) in T-175 tissue culture flasks prior to adenoviral transduction, as previously described ([@B22]). NSCs were further engineered for high transient expression of a modified human CE (hCE1m6) by transduction with a replication-deficient adenoviral construct. *In vivo* Animal Studies ------------------------ All animal studies were conducted under a protocol approved by the City of Hope Institutional Animal Care and Use Committee (IACUC \#04011). Male and female CE-deficient/severe combined immunodeficiency (*Es1*^*e*^/SCID), athymic nude, or C57BL/6 mice (8--12 weeks old) were injected with 2 × 10^5^/2 μl U251T.eGFP.FFluc human glioma cells (U251T; *n* = 6); 2 × 10^5^/2 μl patient-derived PBT017.eGFP.FFluc glioma cells passaged in a mouse brain (PBT017; *n* = 6); or 5 × 10^3^/2 μl GL261 mouse glioma cells (*n* = 5) into the right (U251T and GL261) or both frontal lobes (PBT017). Tumor cells were injected at three different depths 2.25, 2.00, and 1.75 mm. At day 10, post U251 tumor implantation, 2 μl of bolus injection of 4 x10^5^ CE-NSC DiI labeled cells were injected into the left lateral ventricle (+9.0 mm left and −0.3 caudal from bregma) at a depth 2.5 mm. PBT017 (day 14) and GL261 (day 7) tumor bearing mice were given the bolus injection (IVEN) of CE-NSC Molday ion rhodamine B labeled cell at a concentration of 4 × 10^5^ per 2 μl (PBT017) and 2 × 10^5^ per 2 μl (GL261) using same coordinates. CE-NSCs (4 × 10^5^ cells/2 μl) labeled with Molday ION Rhodamine B were administered into the left lateral ventricle on day 10 post U251 implantation; day 14 post PBT017 implantation; or day 7 post GL261 implantation (each tumor latency and engraftment time was previously determined: Aboody et al., unpublished data). Mice were monitored daily for distress and discomfort in accordance with the recommendations of the Panel of Euthanasia of the American Veterinary Medical Association. Euthanasia was conducted on day 3 after CE-NSCs administration in a CO~2~ chamber that enabled visualization of the animals to minimize distress during euthanasia with a gradual increase in the flow of CO~2~. Histopathology and Staining --------------------------- Brains were fixed in 4% paraformaldehyde (PFA) for 72 h and transferred to 70% EtOH (or 30% sucrose) solution for dehydration for 3--5 days. Frozen brain sections were prepared (10 μm) and every 10th section was stained with hematoxylin eosin (HE) to detect the tumor and Prussian blue staining using an Accustain Iron Stain Kit (Sigma-Aldrich) to identify the presence of CE-NSCs. Tumors and CE-NSCs were visualized by bright field imaging. 3D Reconstruction ----------------- Three-dimensional reconstruction was performed using Reconstruct software (SynapseWeb, version 1.1). 9--15 images of serial 10 μm H&E and Prussian blue-stained brain sections were imported into Reconstruct and aligned manually. To produce a 3D image, structures of interest were segmented based on color (Prussian blue for NSCs) and cell density (HE to highlight tumor areas), as described previously ([@B13]). Analysis of CE-NSC Spatial Distribution --------------------------------------- CE-NSCs in the mouse brains were identified and quantified to elucidate the patterns of spatial distribution in the brain, especially around the tumors. CE-NSCs stained in Prussian blue were identified on each of the IHC stained slices using the open-source image processing software ImageJ ([@B31]). The centers of the clusters of CE-NSCs identified using "color thresholding" and "analyze particles" tools were tabulated. A tumor mask was generated by manually delineating the edges of the tumor using the "polygon selection" tool. The center of this mask was identified as the tumor center of mass and the distance and orientation of the CE-NSC clusters with respect to the tumor center was calculated. The results for all the IHC slices were combined to generate a polar histogram in MATLAB 2018a (Mathworks, Natick, MA) representing the spatial distribution of CE-NSCs with respect to the tumor center for each mouse brain. The size of the bars in the plots indicates the percentage of NSCs found along that radial direction, and the color of the bars indicates the distance from the tumor center. Because mice implanted with the PBT017 cell line were injected with dual tumors, CE-NSCs identified in the left hemisphere were associated with the tumor in the left hemisphere and CE-NSCs identified in the right hemisphere were associated with the tumor in the right hemisphere. Thus, 2 polar histograms were generated for each mouse. Results {#s3} ======= Migration and Localization of IVEN-Administered CE-NSCs to Brain Tumor Sites *in vivo* -------------------------------------------------------------------------------------- To initiate a xenograft model of glioma, adult *Es1*^*e*^/SCID immunodeficient mice were implanted with U251T.eGFP.FFluc cells into the right frontal lobe. On day 10, Molday-labeled CE-NSCs were administered into the left lateral ventricle. When injected IVEN into U251T glioma-bearing mice, CE-NSCs migrated to tumor xenografts established in the opposite hemisphere ([Figures 1](#F1){ref-type="fig"}, [2](#F2){ref-type="fig"}). These CE-NSCs were visualized in the vicinity of the tumor and were not detected in non-tumor brain parenchyma. {#F2} The distribution of Molday-labeled CE-NSCs to U251T tumors was also quantitated in athymic nude mice. CE-NSCs were visualized by Prussian blue staining ([Figures 2A--D](#F2){ref-type="fig"}) and migration was quantitated by polar histogram ([Figure 2E](#F2){ref-type="fig"}). The polar histogram shows the quantified spatial distribution of CE-NSCs around the tumor, including both the number of CE-NSCs in various directions and their distance from the tumor center. CE-NSCs demonstrated preferential localization around the tumor, with the CE-NSCs closest to the tumor along the superior-medial and inferior sides. CE-NSCs along the medial direction and far from the tumor represent those in the contralateral ventricle. Migration and Localization of CE-NSCs to Bilateral PDX Tumor Sites Following Injection Into the Left Ventricle -------------------------------------------------------------------------------------------------------------- To analyze migration of CE-NSCs to multiple tumor foci within brain parenchyma after IVEN administration, dual tumors were initiated in *Es1*^*e*^/SCID mice via bilateral administration of human patient-derived glioma cells PBT017. Fourteen days later, CE-NSCs were administered into the left ventricle, after which the CE-NSCs migrated to both left and right tumor sites ([Figure 3](#F3){ref-type="fig"}). Migration of the CE-NSCs was analyzed by 3D reconstruction ([Figure 3](#F3){ref-type="fig"}) and polar histogram analysis ([Figure 4](#F4){ref-type="fig"}). Since a tumor was inoculated in each hemisphere, a polar histogram was generated for each tumor with CE-NSCs identified in any given hemisphere attributed to the tumor present in that hemisphere. The histological sections show substantial CE-NSC presence around the tumors ([Figures 4A,D](#F4){ref-type="fig"}). This observation is reflected in the polar histograms ([Figures 4B,C,E,F](#F4){ref-type="fig"}) with nearly all the bars in blue indicating CE-NSCs in the proximity of the tumor. Strong signals indicate preferential localization of CE-NSCs along the superior-medial and inferior directions, indicating possible migration of CE-NSCs into the tumor along these directions. Notably, one mouse ([Figure 4A](#F4){ref-type="fig"}) was observed to contain equivalent distributions of CE-NSCs in both hemispheres, whereas another mouse ([Figure 4D](#F4){ref-type="fig"}) was observed to contain a significantly higher distribution of CE-NSCs in the tumor in the left (ipsilateral to CE-NSC injection site) hemisphere. {#F3} {#F4} Migration and Localization of CE-NSCs to Gl261 Murine Glioma Tumor in C57BL/6 Mice ---------------------------------------------------------------------------------- C57BL/6 mice were injected with GL261 cells (5 × 10^3^ cells/2 μl) into the right frontal lobe, as described above. On day 7 of the study, CE-NSCs were injected into left lateral ventricle. CE-NSCs demonstrated robust migration from the ventricles into the tumors. The histological section presented in [Figure 5B](#F5){ref-type="fig"} exhibits what appears to be active migration of CE-NSCs from the ventricles and partially from the subarachnoid space/tumor administration needle track. The invasion of the tumor by CE-NSCs from the superior end is also reflected by the blue bar in the polar histogram ([Figure 5C](#F5){ref-type="fig"}) toward the superior direction. CE-NSCs along the medial direction and far from the tumor represent those in the contralateral ventricle. Aggregation of CE-NSCs in the contralateral ventricle was observed. {#F5} Discussion {#s4} ========== Innately tumor-tropic NSCs are able to penetrate the BBB and migrate through brain parenchyma to efficiently localize to both the primary brain tumor site and invasive foci that often seed recurrent disease. These features provide an unprecedented opportunity to develop an effective, tumor-selective therapy for patients with malignant brain tumors. NSCs can produce increased concentrations of tumor-localized chemotherapy while minimizing toxicity to normal brain tissue. We have demonstrated the efficacy of ICT-administered CE-NSCs + IRN in preclinical studies; however, there are multiple drawbacks to ICT administration of NSCs to brain tumor patients, as described above. Our data demonstrate that IVEN administration of NSCs results in similar distribution and tumor coverage in orthotopic tumors that are both proximal and contralateral to the site of injection. By administering NSCs IVEN rather than ICT, we can optimize therapeutic dosing and potentially increase distribution to tumor sites throughout the brain. Specifically, the major advantages include: (1) the ability to dose escalate NSCs beyond volume restrictions for ICT administration; (2) improved NSC viability in CSF; (3) no intratumorally placed catheter tips; (4) improved feasibility of performing multi-center studies; and (5) potential for CE-NSC-mediated gene therapy for treating leptomeningeal metastases from primary and metastatic brain tumors. Beyond the current NSC-based enzyme/prodrug converting strategies to increase levels of cytotoxic chemotherapy in brain tumors, we envision using our tumor-tropic NSCs as a platform technology can be further modified for tumor-localized delivery of a variety of anti-tumor products, such as apoptotic agents, oncolytic viruses, and antibodies, which could potentially be administered serially or in combination to maximize therapeutic benefit ([@B32]). Therefore, the impact of optimizing the delivery of NSCs may be far-reaching. It should be noted that several challenges remain for therapeutic optimization. This includes determination of dosing and regimen that results in maximal tumor coverage, and more uniform distribution through each tumor mass. Multiple and complex factors can affect NSC tumor tropism including tumor-derived growth factors hepatoxcyte growth factor (HGF), endothelial growth factor (EGF), vascular endothelial growth factor (VEGF), urokinase plasminogen activator (uPA), extracellular matrices (ECM), stromal cell-derived factor 1 (SDF-1), hypoxia inducible factor (HIF-1α, and inflammatory cytokines (e.g., IL-6 and IL-8) ([@B15]). Thus, tumor size, location, and heterogeneity likely contribute to the non-uniformity of NSC distribution within a given tumor mass. Clinical correlative studies that include more refined and sophisticated imaging analysis, in addition to intracerebral microdialysis and histopathology, may shed more light on this subject. In our first-in-human study, we documented NSC migration to distant tumor foci in the human brain at the time of autopsy. Permission for brain autopsy was obtained from the families of two study participants. The autopsied brains were extensively sampled, including areas adjacent to and distant from the CD-NSC injection site and ipsilateral and contralateral areas of obvious tumor involvement, as well as deep nuclei, periventricular areas, long axonal tracts, cortical gray matter, and subcortical white matter. All of the samples areas were assessed for the presence of CD-NSCs by nested PCR for the v-*myc* gene. In both brains, v-*myc*-positive areas of single cells were detected distant from the primary injection sites (including the opposite hemisphere) in areas of tumor cells. We observed aggregation of CE-NSCs within the left ventricle (injection site) of a mouse bearing GL261 murine glioma cells ([Figure 5](#F5){ref-type="fig"}). Although the migration of CE-NSCs to the tumor site was evident, such aggregation of CE-NSCs at the injection site might result in a loss of therapeutic efficiency. We suspect that the aggregation was caused by rapid injection of the CE-NSCs. Thus, the rate and number of NSCs injected must be adjusted and properly monitored to achieve optimal therapeutic efficiency. However, human ventricles are much larger than mouse ventricles; therefore, we do not expect such clumping when CE-NSCs are used as therapeutics clinically. We observed that CE-NSCs localized along the superior-medial and inferior directions around the tumors established from U251 and PBT017 cell lines. The superior-medial localization of CE-NSCs can be attributed to invasion of CE-NSCs from the ventricle into the tumor. In mice bearing GL261 tumors, CE-NSCs localized along the superior direction around the tumors, indicating invasion from the subarachnoid space along the tumor cell injection track. We previously demonstrated migration of NSCs along white matter tracts ([@B33]). However, it was also documented that the NSCs migrated with CSF flow through the third and fourth ventricles and subarachnoid space and entered the tumor site through the tumor injection needle track, consistent with our observations. The utilization of such diverse migration routes to tumor sites strongly supports the use of IVEN-delivered CE-NSCs as delivery vehicles for a variety of anti-cancer therapeutics. A potential limitation is the immune mediated impact of delivery of NSCs via IVEN, this will need to be carefully assessed prior to translation to the clinic. Data Availability {#s5} ================= All datasets for this study are included in the manuscript files. The raw data supporting the conclusions of this manuscript will be made available by the authors to any qualified researcher. Author Contributions {#s6} ==================== LF, LT, RT, SA, MM, JG, and AA performed experiments. VA performed quantitative analysis and produced figures. RR and VA designed the quantitative analyses. AA, TS, and JP were involved in discussion and data analysis. MG, KA, and RR led the project, contributed to experimental design, analyses design, review and discussion. All authors reviewed the final manuscript. Conflict of Interest Statement ------------------------------ KA and AA are founders and shareholders of Therabiologics, Inc. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Research reported in this publication included work performed in the Small Animal, Pathology, and Small Animal Imaging Cores supported by the National Cancer Institute of the National Institutes of Health under award number P30CA033572. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. **Funding.** This work was supported by NIH NCI awards R03CA216142, P30CA033572, R01CA198076, the Arthur and Rosalinde Gilbert Foundation, and the Ben and Catherine Ivy Foundation. [^1]: Edited by: Shiv K. Gupta, Mayo Clinic, United States [^2]: Reviewed by: Karishma Rajani, Mayo Clinic, United States; Maria Graciela Castro, University of Michigan, United States [^3]: This article was submitted to Cancer Molecular Targets and Therapeutics, a section of the journal Frontiers in Oncology [^4]: †Co-first authors | High | [
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package org.openapitools.client.model { import org.openapitools.common.ListWrapper; public class OrdSideList implements ListWrapper { // This declaration below of _OrdSide_obj_class is to force flash compiler to include this class private var _ordSide_obj_class: org.openapitools.client.model.OrdSide = null; [XmlElements(name="ordSide", type="org.openapitools.client.model.OrdSide")] public var ordSide: Array = new Array(); public function getList(): Array{ return ordSide; } } } | Low | [
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Q: Error using Logback Marker in FileAppender I have started exploring Logback option for our application. One of the requirement is to create a separate log file for log entries that have a specific "Marker". Below is the logback.xml file that i am using and the error I am getting. The examples on the logback website shows the usage of SMTPAppender but I would like to use FileAppender instead. Is this possible? If not, what other option do i have? <property name="USER_HOME" value="c:/temp" /> <appender name="AUDIT_FILE" class="ch.qos.logback.core.FileAppender"> <evaluator class="ch.qos.logback.classic.boolex.OnMarkerEvaluator"> <marker>APPEND_SYSLOG</marker> </evaluator> <file>${USER_HOME}/mw_syslog.log</file> <encoder> <pattern>%date %level [%thread] %logger{10} [%file:%line] %msg%n</pattern> </encoder> </appender> <root level="debug"> <appender-ref ref="AUDIT_FILE" /> </root> 12:07:01,515 |-INFO in ch.qos.logback.classic.LoggerContext[default] - Found resource [logback.xml] at [file:/C:/JavaProjects/LogbackWeb/target/LogbackWeb-1.0-SNAPSHOT/WEB-INF/classes/logback.xml] 12:07:02,013 |-INFO in ch.qos.logback.classic.joran.action.ConfigurationAction - debug attribute not set 12:07:02,134 |-INFO in ch.qos.logback.core.joran.action.AppenderAction - About to instantiate appender of type [ch.qos.logback.core.FileAppender] 12:07:02,176 |-INFO in ch.qos.logback.core.joran.action.AppenderAction - Naming appender as [AUDIT_FILE] 12:07:02,286 |-ERROR in ch.qos.logback.core.joran.spi.Interpreter@43:76 - no applicable action for [evaluator], current pattern is [[configuration][appender][evaluator]] 12:07:02,286 |-ERROR in ch.qos.logback.core.joran.spi.Interpreter@44:21 - no applicable action for [marker], current pattern is [[configuration][appender][evaluator][marker]] 12:07:02,310 |-INFO in ch.qos.logback.core.joran.action.NestedComplexPropertyIA - Assuming default type [ch.qos.logback.classic.encoder.PatternLayoutEncoder] for [encoder] property 12:07:02,828 |-INFO in ch.qos.logback.core.FileAppender[AUDIT_FILE] - File property is set to [c:/temp/mw_syslog.log] 12:07:02,836 |-INFO in ch.qos.logback.classic.joran.action.RootLoggerAction - Setting level of ROOT logger to DEBUG 12:07:02,836 |-INFO in ch.qos.logback.core.joran.action.AppenderRefAction - Attaching appender named [AUDIT_FILE] to Logger[ROOT] 12:07:02,842 |-INFO in ch.qos.logback.classic.joran.action.ConfigurationAction - End of configuration. 12:07:02,855 |-INFO in ch.qos.logback.classic.joran.JoranConfigurator@3ad1a015 - Registering current configuration as safe fallback point A: In SMTPAppender the evaluator is used for triggering. In FileAppender, you need to encapsulate the evaluator within a filter, an evaluator filter to be precise. Here is an example: <property name="USER_HOME" value="c:/temp" /> <appender name="AUDIT_FILE" class="ch.qos.logback.core.FileAppender"> <!-- the filter element --> <filter class="ch.qos.logback.core.filter.EvaluatorFilter"> <evaluator class="ch.qos.logback.classic.boolex.OnMarkerEvaluator"> <marker>APPEND_SYSLOG</marker> </evaluator> <onMismatch>DENY</onMismatch> <onMatch>NEUTRAL</onMatch> </filter> <file>${USER_HOME}/mw_syslog.log</file> <encoder> <pattern>%date %level [%thread] %logger{10} [%file:%line] %msg%n</pattern> </encoder> </appender> <root level="debug"> <appender-ref ref="AUDIT_FILE" /> </root> | Mid | [
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<!--<div class="w3-panel w3-pale-green w3-leftbar w3-border-green"> <h3> Check out our new project <a href="https://armor.labstack.com">Armor</a> </h3> <p> Uncomplicated, modern HTTP server, supports HTTP/2 and auto TLS </p> </div>--> | Low | [
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Monday, June 04, 2012 OK. I love that people ask me lots of questions about evolution, genomics, microbes, a mix of the two, etc. But I just cannot keep answering single one-off emails about these topics. So I am starting online office hours. If you have any general questions about phylogenetics, evolution, genomics, microbes, or any of the work done in my lab, please post your questions here. And I will try to answer them. 6 comments: I wonder what you think about SSU rRNA genes as measures of community profiles, which are now really common in all of environmental micro and microbial ecology. I also am curious your thoughts on the utility of measures of phylogenetic clustering (like David Ackerley's tool phylocom, but there are many) to infer evolutionary pressures on communities. At first I thought of these tools as breathing new life into SSU ribosomal RNA data, but maybe they distracting us from asking questions about what shapes microbial communities in better, or more sophisticated ways? 1. I think SSU rRNA analyses have been and will continue to be critically important for microbial ecology studies, despite being imperfect 2. With the increasing use of UNIFRAC and QIIME many researchers are in essence doing something equivalent to PHYLOCOM. PD (phylogenetic diversity) is being used extensively to both measure single communities and also to compare and contrast communities. 3. I am not sure these approaches have breathed new life into microbial ecology studies per se. PD and phylogenetic ecology measures are used in microbial studies mostly simply to calculate distance between communities (e.g., with UNIFRAC). There has been much less in the "phylogenetic ecology" area especially in comparison to plants and animals, although see papers like Kembel et al. 2011 (on which I am a coauthor) Hi Dr. Eisen--I'm the National Geographic researcher that's been trying to get in touch with you (Kelsey Nowakowski). I understand that you're getting an overwhelming amount of inquires and I would like to ask mine here, but I'm sure that would breach some type of confidentiality policy I've agreed to follow. That being said, is there anyway you could briefly talk on the phone with me? I just want to check the plausibility of a couple ideas. I assure you it won't take too long. I watched your talk from the Compass Summit. Perhaps this project could help get people interested in a Field Guide to Microbes. I'd buy that app. We have discovered a very unusual enzyme that is involved in the biosynthesis of an antibiotic, which attaches ribose-5-phosphate to the polyaromatic aglycone. We also have the crystal structure of the enzyme available, but that has not been published yet. The enzyme family is very poorly characterized and all of the homologous sequences (~755) deposited into databases are annotated as "pseudouridine glycosidases" that are involved in primary metabolism in degradation of RNA. My suspicion is that some of these sequences are not annotated correctly, but they might be doing something novel/more interesting. The problem we are facing is finding out which ones are the non-pseudouridine glycosidases. To my mind, we have a situation where have in a single phylogenetic tree many orthologous sequences with few (interesting) paralogous sequences. I have been trying to convince myself that the way to identify the paralogous sequences would be comparative phylogenetic analysis, where we construct another tree (from for instance 16S rDNA sequences) that conveys the evolutionary relationships of the various organisms. The "real" psudouridine glycosidases should follow this normal evolutionary distribution (unless there is horizontal gene transfer) and any outliers we may find would be the interesting ones. But it seems to be very annoying for me to do this so - is my logic flawed in some way? Is there a better way to do this? Well, the first thing I would do is build a tree of ALL the homologs and overlay onto that true known experimentally determined functions (rather than annotations). That way you can see if know functions group into any part of the tree. | Mid | [
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Q: How to get string of everything between these two em tag? I want to get string between em tag , including other html also. for example: <em>UNIVERSALPOSTAL UNION - International Bureau Circular<br /> By: K.J.S. McKeown</em> output should be as: UNIVERSALPOSTAL UNION - International Bureau Circular<br /> By: K.J.S. McKeown please help me. Thanks A: Use the regular expression function like this: REMatch("(?s)<em>.*?</em>", html) See also: http://livedocs.adobe.com/coldfusion/8/htmldocs/help.html?content=regexp_01.html The (?s) sets the mode to single line, so that the input text is interpreted as one line even if it contains line feeds. This is probably the default (I'm not sure) so it can be omitted. As Peter pointed out in a comment, this is not the default and therefore must be set. The .*? matches all characters inbetween <em> and </em>. The questionmark after the multiplier makes it "non-greedy", so that as few as possible characters are matched. This is needed in case the input html contains something like <em>foo</em><em>bar</em> where otherwise only the outermost <em></em> tags are considered. The returned array contains all matches found, i.e. all texts including html that was in <em> tags. Note that this could fail for circumstances where </em> also occurs as attribute text and is incorrectly not html-encoded, for example: <em><a title="Help for </em> tag">click</a></em> or in other rare circumstances (e.g. javascript script tags etc.). A regex cannot replace a full HTML/XML parser and if you need 100% accurateness, you should consider using one: http://livedocs.adobe.com/coldfusion/8/htmldocs/help.html?content=functions_t-z_23.html | Mid | [
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## # This module requires Metasploit: https://metasploit.com/download # Current source: https://github.com/rapid7/metasploit-framework ## class MetasploitModule < Msf::Auxiliary include Msf::Auxiliary::Report include Msf::Exploit::Remote::Udp include Msf::Auxiliary::UDPScanner include Msf::Auxiliary::NTP include Msf::Auxiliary::DRDoS def initialize super( 'Name' => 'NTP Mode 6 UNSETTRAP DRDoS Scanner', 'Description' => %q{ This module identifies NTP servers which permit mode 6 UNSETTRAP requests that can be used to conduct DRDoS attacks. In some configurations, NTP servers will respond to UNSETTRAP requests with multiple packets, allowing remote attackers to cause a distributed, reflected denial of service (aka, "DRDoS" or traffic amplification) via spoofed requests. }, 'Author' => 'Jon Hart <jon_hart[at]rapid7.com>', 'References' => [ ['CVE', '2013-5211'], # see also scanner/ntp/ntp_monlist.rb ['URL', 'https://github.com/rapid7/metasploit-framework/pull/3696'], ['URL', 'http://r-7.co/R7-2014-12'] ], 'DisclosureDate' => 'Aug 25 2014', 'License' => MSF_LICENSE ) end # Called for each response packet def scanner_process(data, shost, sport) @results[shost] ||= [] @results[shost] << Rex::Proto::NTP::NTPControl.new.read(data) end # Called before the scan block def scanner_prescan(batch) @results = {} @probe = Rex::Proto::NTP::NTPControl.new @probe.version = datastore['VERSION'] @probe.operation = 31 end # Called after the scan block def scanner_postscan(batch) @results.keys.each do |k| response_map = { @probe => @results[k] } # TODO: check to see if any of the responses are actually NTP before reporting report_service( :host => k, :proto => 'udp', :port => rport, :name => 'ntp' ) peer = "#{k}:#{rport}" vulnerable, proof = prove_amplification(response_map) what = 'R7-2014-12 NTP Mode 6 UNSETTRAP DRDoS' if vulnerable print_good("#{peer} - Vulnerable to #{what}: #{proof}") report_vuln({ :host => k, :port => rport, :proto => 'udp', :name => what, :refs => self.references }) else vprint_status("#{peer} - Not vulnerable to #{what}: #{proof}") end end end end | Mid | [
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Q: My page CSS is broken in IE8, why? Trying to figure out what I have done wrong One of my pages css seems to be a little broken in IE8. I thought if I added clear:both the problem would have been fixed but the elements are still...well please, see for yourself: A: "A little broken" is not a technical description. IE8 is not aware of HTML5 elements so you cannot style them like a modern browser. You need to add the HTML5 shiv which is javascript that will inform IE8 of those elements and allow you to style them. As it sits, any CSS styling you give things like article will be ignored. Just copy this into the head of your page to see what happens: <!--[if lt IE 9]> <script src='http://html5shiv.googlecode.com/svn/trunk/html5.js'></script> <![endif]--> | Mid | [
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Q: Text is not wrapping inside absolute positioned div I'm having an issue getting text to wrap inside an absolute positioned div. I think the problem is I have a the width set to 100% which I have to have because the div resizes with the page. How can I get the text to wrap. Here's my code: #content {
background: black;
min-height: 60px;
background: #0a0a0a;
position: relative;
padding: 0;
overflow: hidden;
}
#content .entry {
background: white;
position: absolute;
text-wrap: normal;
top: 0;
left: 200px;
padding: 10px;
width: 100%;
height: 100%;
min-height: 50px;
border-left: 1px solid #262626;
} <div id="content">
<div class="entry">
<-----text---->
</div>
</div> A: The problem is that you declare a width of 100% AND a left of 400px on the .entry elements. The total width will be 100% + 400px which will make the .entry element wider than its container. It does wrap its text, but you won't see the rightmost 400px of it. The problem is that you cannot define the width and the padding/margin/left/right/etc on the same element. You need a nested structure to get it done. So, add an extra div in the content > entry html structure and define the width on the first one and the padding on the second. | Low | [
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H&M Sail Summer Sleeveless Dress. Size 6. No sign of wear besides small bleed on the back/bottom of dress. Since it's on white I think it can be bleached out/Tide stick-ed. I never tried it. Really cute and fun to wear to the beach or just out. Tie waist. Cotton. | Low | [
0.399515738498789,
20.625,
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Skor responds to reports EPA may change policy on RINs, exports By Growth Energy | September 28, 2017 ADVERTISEMENT Growth Energy CEO Emily Skor issued the following statement in response to emerging media reports of an effort by oil refiner Valero to encourage the U.S. EPA to attach renewable identification numbers (RINs) to exported biofuel, primarily corn-based ethanol. This action would run counter to the Renewable Fuel Standard statute and comes on the heels of a misguided attempt by Valero, Carl Icahn, and other merchant refiners to shift the obligated party under the RFS. “While we cannot speculate on whether this rumor is being given any sort of official consideration, what is absolutely clear is that the idea runs contrary to the intent and plain language of the statute, which is specifically constructed to blend more renewable fuel into the U.S. transportation fuel supply in order to give consumers cleaner, more affordable fuel choices at the pump,” Skor said. “Between these media reports and yesterday’s proposed cuts to the 2018 renewable volume obligations (RVOs), we are concerned about the EPA’s and the administration’s commitment to supporting biofuels.” The Federal Register clearly noted that the EPA has ruled previously that, “if a gallon of ethanol is produced in the U.S. but consumed outside of the U.S., the RIN associated with that gallon is not valid for RFS compliance purposes since the RFS program is intended to require a specific volume of renewable fuel to be consumed in the U.S.”* | High | [
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3rd Study in Just 5 Months, Proves Once Again, Cannabis Annihilates Epilepsy in Children Spread the love The story of 13-year-old Cyndimae Meehan is a powerful study in the moral imperative of ending the drug war. Cyndimae suffered from Dravet syndrome since she was 10 months old, which caused daily and repeated seizures. After trying 23 different FDA-approved pharmaceuticals which did nothing but put Cyndimae in a wheelchair, her parents were forced to become criminals and seek out medical cannabis. They found a source in prohibitionist Connecticut, and the results were miraculous. Cannabidiol (CBD) oil—a non-psychoactive extract of cannabis—stopped Cyndimae’s seizures in its tracks, as seen in a video from March. The girl enjoyed a tremendously better quality of life because of this plant extract. “When I met Cyndimae three years ago, she was in a wheelchair, was unresponsive and had a blank stare on her face. She was a shell of a child,” said Brian Breton, who leads Maine Children for Cannabis Therapy. “Now she runs and laughs and colors and goes swimming. She’s an inspiration to all of us.” Sadly, after 2½ years of living in Maine with legal access to medical cannabis, Cyndimae passed away. Though CBD oil gave her an unprecedented quality of life, even it could not prevent the full severity of Dravet syndrome. Cyndimae and her parents had become strong voices in the fight to end the senseless prohibition of medical cannabis that still grips some states and the federal government. She was living testimony to the power of cannabidiol, a non-psychoactive extract of cannabis, to treat epileptic seizures where pharma drugs fail. The science is now undeniable. Studies are repeatedly confirming the extraordinary medical value of cannabidiol. In five months, three clinical trials have taken medical cannabis to the forefront of epilepsy treatment. The latest study may result in the first cannabis-derived drug to be approved by federal regulators for prescription use. Epidiolex, which is almost pure CBD, “significantly reduced seizures in severely epileptic children, according to a landmark study conducted in part at Lurie Children’s Hospital of Chicago.” “The study at Lurie was part of a nationwide clinical trial conducted by the drug’s maker, GW Pharmaceuticals. While a preliminary study also produced encouraging results, the company said this was the first trial of plant-based CBD involving a randomized, double-blind placebo control, known as the gold standard of disease research… The study involved about 120 patients, aged 2 to 18, who have Dravet syndrome and whose seizures were resistant to existing medications. Among patients who received the drug, convulsive seizures were reduced by an average of 39 percent, compared to 19 percent for the placebo, over 14 weeks last summer, according to results announced in March.” One patient with Dravet syndrome, 5-year-old Caleb Yunk, went 100 days without a seizure. He was able to move away from other pharma drugs that produced serious side effects. “His eyes sparkle more,” said his mother, Kelley Yunk. “He’s more engaged. I think he’s more cheerful. For our family, it was such a huge blessing.” The promising results of Epidiolex trials have granted it Fast Track status from the FDA. This study builds on prior research that was presented in December at the American Epileptic Society, which showed Epidiolex to have astounding results. “Of 261 patients given CBD treatment, 45% experienced a significant reduction in seizure frequency, and 9% were seizure-free at 3 months. Some children continued to experience benefits after the trial ended, even one year after. “In the subsequent periods, which are very encouraging, 9 percent of all patients and 13 percent of those with Dravet Syndrome epilepsy were seizure-free. Many have never been seizure-free before,” said lead author Dr. Orrin Devinsky.” These clinical trials build on the exponential growth of medical cannabis research that has taken place in the last couple of years, as state governments continue to decriminalize the plant and irrational fears about it dissipate. In March, we reported on another successful clinical trial conducted at the University of Alabama at Birmingham, where 90 percent of patients experienced “some improvement.” “Dr. Jerzy Szaflarski, head of the Division of Epilepsy at UAB and a principal investigator in the study, told AL.com: “We have noticed that at least 50 percent of the patients have more than 50 percent reduction in seizures, which is very nice. Some of these patients have multiple seizures per day. They report on CBD that they have days without seizures, which is great.” This was the largest study of its kind to date, and is being presented at the time of this writing to more than 10,000 neurologists at the American Academy of Neurology meeting. It will surely accelerate the growing interest in using CBD for treatment of various types of epilepsy. As Dr. Szaflarksi noted, “The majority of the seizure medications that are on the market have some negative effects of cognition. Here, we observe something to be different.” The weight of scientific evidence continues to make prohibition look ever more absurd. The only real criminal act taking place is government continuing to deny medical cannabis to people. Some politicians are taking a stand. Rep. Allen Peake, a Georgia lawmaker, defies unjust cannabis prohibition by bringing medical cannabis into Georgia from states where it is legal. This incredibly noble and brave practice is helping desperate parents bring relief to their suffering children. “I got a text this morning from the mother of a young child who I delivered product to,” said Peake. “And the heartfelt thanks from this mother, the difference in this child – the increase in cognitive ability, the reduction in seizures, has been worth every bit of risk that I’ve taken.” The case for medical cannabis is clear. The time for government to end its harmful crusade is now. Spread the love Sponsored Content: | Mid | [
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"Yes!" "It is possible!" "Man can fly." "No, no, no..." "this can't be happening!" "A chicken?" "How bizarre." "Even if a flightless bird could assend this far into the stratisfier the lack of oxygen would make breathing nearly impossible." "Also, he's wearing pajamas so this must be..." "A dream." "Precisely." "But we are still, however, going to crash and it will hurt." " The bank's being robbed!" " Quickly!" "Surround the building!" "You go that way!" "You go this way!" "There he is!" " Come on!" " After him, men!" "That way!" " He came this way." "I'm sure of it." " Come on!" "Come on, mates!" "Keep up!" "Sorry, sir." "Today is the day I will finally achieve what has been deemed impossible." "Man can break the 50-mile-per-hour speed barrier." "And you, you're lucky enough to be a part of it, Pierre." " It's Jean Michel, sir." " Yes." "We will make history." "Or we will die trying." " Die?" " This is very exciting." "That's it!" "I refuse to be catapulted, electrocuted, or have my internal organs disrupted any longer!" "I quit!" "He is a very sick man!" "The electrocution was not my fault!" "You refused to wear the rubber underpants!" "We're looking for a bank robber." "Is there no man brave enough to be my valet?" "Oh..." "Aah!" "I'm your new valet." "Uh..." "I must commend the valet service on their... impeccable foresight." "But they know I only accept French valets." "Yes." "Oh!" "Oui!" "Oui!" "I come from a long line of French valets." "On my father's side." "Very, very French." " But your accent..." " My father French." "Never speak." "My mother Chinese and never shuts up." "All the children pick up her accent." "Very well." "Uh..." "Will you be willing to risk your life to challenge the laws of physics as we know them?" " Yes." "Uh, and I can sing, too." " Excellent." "Pop this little hat on." " He's got to be in here." " He's this way!" "And the throttle in your right hand controls the speed." " How do I stop?" " Godspeed!" "Twenty-five miles per hour." "Yes, the pressure's stable-ish." "We need more speed, man." "Forty miles per hour." "Hang on in there, my good man." "Forty-seven." "Forty-eight." "Forty-nine." "Eureka!" "We've done it!" "Uh..." "I say, I say." "Uh, good morning." " I'm looking for a-a man with..." " Over here!" "Ah, there-there he is." "There's my valet." "Sorry!" "New valet." " Good morning." " Good morning." "You'll be able to let go any second." "The pack will run out of steam in exactly three, two, one..." "Now." "Look out!" "That was incredible!" "Well done!" "We've broken the human speed barrier." "Good-bye, sir." "It's been very nice valeting for you." "Let's... do it again soon." "Bye." "Hey, wait." "Please, wait, wait!" "Well, with you as my... brave valet, I can test all my inventions." "No!" "Spread out!" " Cover that..." " Yes, yes, yes." " I take the job." " Splendid!" "I can't wait to present my results to the Royal Academy." "Too kind." "Too kind." "Thank you." "And with this grant to develop new applications for copper wire," "Dr. Ramsey invented this." "Needless to say, the Royal Academy of Science declared this crackpot mentally incompetent, and he was duly dispatched to a lunatic asylum." "Sir." "I have an urgent announcement for you." "Here." "Well, don't just stand there, man." "Read it." "What?" "Oh." "Um..." ""It is with great distress that Scotland Yard announces that the Bank of England..." "has been robbed."" "My stolen jade Buddha stolen?" "You blighter!" "You gave me every assurance that the Bank of England was impenetrable!" "Sir, sir, I said "impregnable"." "It's the same thing, you idiot!" "Please, please, not the quills!" "Lord Salisbury!" "Please contact general Fang and inform her, no Buddha, no deal." "To forgo your obligation would be dishonorable, Lord Kelvin." "A woman in the Royal Academy?" "The jade Buddha was successfully delivered by us to the Bank of England." " What happens while it's in British hands..." " ..." "Is absolutely your concern." "Colonel Kitchner, chief of Scotland Yard, please inform general Fang what other items were stolen from the Bank of England." "Nothing else." "Exactly." "It seems your little land dispute has spilled over onto our noble shore." "Until the jade Buddha is back in my possession, you and your cause will receive no British military assistance whatsoever." "Kitchner!" "My agents will retrieve the jade Buddha once again, Lord Kelvin." "This time, do not let it slip through your fingers." "A female general." "What sort of pathetic man takes orders from a woman?" "Cor!" " Come away from here." " Oh, dad." "Can't we stay?" "My wind-powered pulley system circulates the house with fresh air." "Kitchen items are to be placed on the white boat, and the blue is for laundry." "But most importantly, this supplies the house with a running current of electricity." "Electricity." "This is my comprehensive data schedule and list of regulations." "It's quite simple." "You're never to divert one iota from my plans." "I must live my life with total efficiency, to maximize my inventing capacity, thus enabling me to do the most I can for mankind." "Uh, Mr. Fogg, you are a noble, precise gentleman." "Thank you." "Uh..." "Sorry." "What was your name?" "Ahem." "Uh?" "Passport." "Too." "Passepartout." "Bottled light." "A miracle." "Hardly." "Just undiscovered science from an American named Thomas Edison." "It turns on with a whistle." "Please, don't do that." "Ah, see, your eye is drawn to what I hope will one day be my crowning achievement." "A giant moth?" " It's a flying machine." " It can fly?" "Yes." "No." "But it will... one day." "When I've worked out the problem with the steering cables and that damned chicken." "One day it will transport people through the air." "Perhaps over entire oceans." "Uh-oh." "I think I'm going to have to make a rule for this." ""Dear father:" "I will find the fastest way back to China... to make our village safe once again."" "Passepartout?" "Departure for the Royal Academy of Science in two minutes." "Prepare my urban transport device." "It's the shoes with little wheels on them." "Clear the way." "Clear the way." "Mr. Fogg coming through." "Watch out!" "Watch out!" "Excuse me." "Out of way." " Gangway, gangway." " Fogg's arrived." " Gangway." "Ooh!" " Hey!" "That makes it exactly ten minutes before noon." "That will be all." "Gentlemen." "Today I have proved that man can break the 50-mile-per-hour speed barrier without disrupting his internal organs." "Where is your Royal Academy of Science authorization?" "What am I thinking?" "What a fool." "That would mean that you were a real scientist!" "By your definition, Kelvin, a real scientist's objective would be to prevent man from progress." "We live in a golden age, Fogg." "Everything worth discovering has been discovered." "Yet, ridiculous dreamers like you insist on a past filled with..." "dinosaurs... and evolution." "And on a future filled with motorized vehicles, radio waves, and flying machines!" "Confound it!" "The bloody Bank of England is a madhouse!" "Rumor has it the bloke's a foreigner." "An Asian chap." "Rumor has it the bloke's a foreigner." "Nothing." "Yes, I heard it was a Chinese fellow, and he acted alone." "Uh, no." "Actually, they say he was Norwegian." "In fact, though, it was a gang of elderly Norwegians." "Yes, I heard it from a very reliable source that it was a gang of redheaded elderly Norwegians with very tiny feet." "Well, if you ask me, it's about time someone robbed that bank." "Like this very institution, the Bank of England is outdated." "As usual, Fogg, your contempt for tradition is appalling." "You rest on your... traditions, if you prefer, but, as with this bank robber, progress waits for no one." "Oh, so now you're an expert on the bank thief as well." "Give us the benefit of your ineffable wisdom, Fogg." "Twenty-six minutes ago, a ship left Dover for Paris." "From there, the thief takes the Orient Express, where he transfers to a steamer, from Istanbul to India." "In little over a month, that man could be in China." "If we're to believe Fogg's calculations, he will have circled the globe and returned to England in a fortnight." "Actually, by my calculations, it would be closer to, uh, exactly 80 days." "Outstanding idea." "Well, then, Fogg, let's see you circumnavigate the world in 80 days." "I..." "That would be a fruitless use of my time." "I'm on the verge of..." "numerous... countless..." "scientific breakthroughs." "You coward." "Admit it." "It cannot be done." "It can!" "I could do it." "A wager." "10,000 pounds." "Unlike you and your colleagues, money does not inspire me." "I believe every man has his price." "Even you, oh, noble Phileas Fogg." "There must be something I could offer you that would be worthy of your time." "There is." "Your position as head of the Royal Academy." "With the queen's heir, I could..." "lead Britain and the rest of the world into a new age of progress and discovery." " Fair enough." " What?" "I, Lord Kelvin, hereby vow to surrender my position as minister of science to Phileas Fogg..." " No!" " No!" "No!" "...if he can circumnavigate the globe... in no more than 80 days." "But if he cannot, he must never set foot in this academy again, he must tear down that abhorrent eyesore he calls a laboratory, and he must swear never to invent again." "Just as I always suspected, Fogg." "You promise so much, yet you deliver... oh, nothing." " I'll-I'll take your wager." " What did you say?" "I'll take your wager!" "He did it." "Then it's done." "A man who has never set foot out of England circling the globe." "This is going to be rather amusing." "History won't remember your amusement, Lord Kelvin, but it will be hard-pressed to forget the moment I'm standing on the very top step of the Royal Academy of Science." "By the strike of noon, after I, Phileas Fogg, have travelled around the world in 80 days!" "Oh, dear." "Mr. Fogg, we all pack and ready to go." "Mr. Fogg, are you in here?" "Phileas!" "Phileas!" "Phileas!" " Uh..." " Mr. Fogg, are you well, sir?" "Huh?" "Uh, Passepartout." "Would you..." "sit with me a moment?" "Yes, sir." "I risked everything, my entire life's work." "For something you believe in." "Nothing could make more sense than that, sir." "You are an honourable man, Passepartout." "But I'm afraid this was a calamitous lapse of judgement." " Mr-Mr." "Fogg?" " Yes?" " Maybe we should let your family..." " There really is... no one left to tell." "This house and... my inventions are all I have." "And a brave new French valet that will help you make it around the world in 80 days." " You really believe we can succeed?" " Yes." "Yes." "Yes." "Yes!" "You're mad." "We'll be sliced to pieces before we reach India." "We're with you, sir!" "Good luck!" "Halt!" " Quite a contraption you got here, Mr. Fogg." " I thank you, inspector." "But I'm afraid I'm gonna have to detain you and your valet until further notice." "You see, this here doohickey is in violation of the city's new vehicle code." "Vehicle code?" "Code 431." "All vehicles must be powered by horses." "Or other indigenous quadruped creatures of the like, excluding giraffes and..." "My good man, you're driveling." "Now stand aside." "I'm about to embark upon a journey around the world." "Not in this monstrosity, you're not." "No!" " Mm-mm." " That's hot." "It's..." "Ow!" "Time to go." "We have a boat to catch." "Stealing a police vehicle is not an acceptable way to begin our journey." " Not stealing." "Borrowing." " Ah." "Excuse us." "We're just borrowing this vehicle to catch our ship to Paris, if someone could inform the appropriate authorities." "Bloody hell!" "Me brain's leakin'!" "Ahh!" "Damn that nincompoop Fix." "What's the point of hiring a corrupt police officer if he can't even abuse the law properly?" " Kitchner." " Sir!" "Tell inspector Fix to pack his bags." " He's going on a little trip." " Right away, sir." "Retrieve the jade Buddha in Paris." "As for Lau Xing..." "Kill him!" "Hmm." "Smart man." "Passepartout, will you tell this impudent fellow that we must leave within six and a half hours, or we miss our connection in Constantinople." "Yes, sir." "Please." "We are in a great hurry." " Passepartout?" " Yes?" "In French." "Sacre bleu, la champignon, chateau, bien, françois, voila, ooh-la-la, foie de gras." "T'as I'air malade, toi." " What did he say?" " Uh..." "He say..." " What?" " He says not to worry." "The next train will leave in five hours." "Good time for sightseeing." "Passepartout, this is a scientific expedition, not a holiday!" "I will not miss this train." "Ah!" " Very amazing." " What?" "What does it say?" "This week only Eddie Thomason will be showing his new inventions." "Thomas Edison?" "Here in Paris?" "What a chance for you to meet another great inventor." "Ah..." "I would quite like to... tell him about my whistle modification." "Good idea." "See?" "Exposition." "Science." "I assure you these are not the works of Thomas Edison." "Uh, I think he is somewhere around here." "Wait a moment." "This isn't science." "This is art." " Yeah." " Hmm." "That painting is highly inaccurate." "It's not supposed to be accurate." "The artist views reality through imagination rather than simply recording it." "It is called... "impressionism"." "Well, um, I'm not impressed." "Trees are not violet, grass is not charcoal, and a man cannot... fly." "You feel something." "You dream of flying." "Or of naked men." " Sometimes." " Ah." "The flying." "N- n-not the men." "I'm glad you like my painting." "Monique La Roche." "Phileas Fogg." "Well, I must say, it's a lot better than these... amateurs." "What did he say?" " Oh, no." " Oh, no, not again." " Who's responsible for this vandalism?" " It's mine, sir, does it please you?" "Please me?" "No." "You want to hang something?" "Go hang people's coats as you were hired to do!" " But sir..." " In fact, don't!" "You're fired!" "Leave art to the artists." "Goodness." "What was all that about?" "Well, a wealthy gentleman bought my painting for a lot of money." "Champagne for everyone!" "I'm still looking for Mr. Eddie." "Nice painting." "Have you ever considered a career in schematic drawing?" "No." "It would be far too limiting." "At least your work shows genuine promise." "Thank you." "Those I painted many months ago." "I was..." "lacking inspiration." "I found some men to help me find Mr. "Edimon"." " This way." " Thank you." "Thank you." "He's very eager." "Get him!" "Oh, no, no, no, no." "Oh, it's terrible, no?" "No, no, it's... clever." " Oh." "Hmm." "Yes." " He's a clown." " Mm-hmm." "And yet... he's incredibly angry." "Oh, the... the irony is, uh, terrifying." " Is that good?" " Is it?" "Ah, this is interesting." "Of course, you do realize that, without opposable thumbs, a dog could never play poker." "Yes, they can." "And where have you ever seen a dog playing poker?" "Right there." "Yes, perhaps I'm not the best judge." "Bandits!" "They come to take away all the paintings!" "Look out." "My paintings!" " Quickly!" "Come this way!" " Passepartout!" "Go, go, go!" "Thank you, Miss La Roche." "You may just have saved our trip." " There you are." " I would, uh..." " I would like to repay you." " Then take me with you." " What?" " I'm stifled here." "Pigeonholed." "They think of me only as a... a coat-check girl!" " Why?" " Because I am the coat-check girl." " Ah." " Look." "The leading art critic in Paris." "Look what he wrote about one of my paintings." " I can't read this." "I think it's French." " I wish I couldn't." "Why do you carry it around?" "When I do succeed, I can throw it in his face, but for now," "I need a world journey to inspire me." "I'm inspired to get us back on schedule." "Let's see." "Wind velocity approximately twelve knots, factoring in air density..." "Outstanding!" "Passepartout, onward!" "Ah." "Hey, there we go." "Passepartout, tell him to keep the change." "Uh... pathe, fromage, por favor." "We are going around the world in 80 days!" "My God!" "They are Mad!" "Please, Miss La Roche, the balloon cannot support all this weight!" "Your hot air should compensate, no?" "Get off!" " What are they doing?" " Well, they're being disorderly." "Hey!" "Let go!" "Let go!" "Hey!" "Passepartout!" "My valise!" "It has all my money in it." "Hey, lady, lady, lady!" "It's my bag." "No, that is my bag." "No, that's not your bag." "It's my bag!" " No!" " You crazy." "Yes." "That tickles!" "You took my bag." "Mr. Fogg!" "Good catch!" " Thank you." "Ooh!" "Those are the gallery bandits." "Ho, ho, ho!" "Oh, yes!" "He stole my purse!" "This devil stole my purse!" "My bag!" "He took my..." "Ah!" " We've stolen that old lady's purse." " Huh." "Here." "We must help Passepartout." "How do I make this go lower?" "What are you doing?" "You decrease the overall weight then..." "That's not going to work." " Yes, it is." "Physics, no?" "Yes." "Ahhh..." "Bonjour." "Bonjour." " Eh?" " Bye-bye!" "Wake up, lady!" "Wake up!" "Wake up, lady!" "Wake up!" "Lady, wake up!" " Bye, mama." " Merci." "Bye, baby." "Ohh..." "Very impressive." "I'd have let go by now." "The statue's grabbing his trousers." "I don't think it's doing it on purpose." "Oh, dear." "Help!" "Well done, Passepartout." "We're still on schedule despite those dogged thieves." "Yes, yes." "Thank you." "Those art thieves seemed to recognize you." " I look like someone they know." " Some other Frenchman, perhaps?" " So, where can we drop you off?" " We're not stopping." "Once we land in Munich to board the Orient Express, you are free to go." "Thank you so much." " For what?" " For saying I'm free to go with you." "No, no." "I did not say you were free to come." " I said you were free to go." " Where?" " Anywhere." " Yes, thank you." "I will go with you." " No, you will not, Miss La Roche." " Monique." "Miss..." "Monique!" "There!" "Now we are getting along." "Comme c'est beau." "C'est magnifique." "Toutes ces couleurs." "Look at the sunrise." "There is only one word for it." " "Magical."" " Miss La Roche!" "I refuse to allow you to continue travelling with us." "I'm not travelling with you." "I'm making my own way." "Maybe you shouldn't travel with me." "This is what happens when you leave your home." "You meet... people!" "Why are you keeping up this... ruse?" "Perhaps I should inform Mr. Fogg, and together he and I can speculate." "A very sacred object was stolen from my village." "I have taken it back." "Incroyable." "For many centuries, the jade Buddha has protected my people." "It has never left our village... until now." "And those art thieves." "Who are they?" "The Black Scorpions." "They work for an evil warlord." "Fang." "She wants the Buddha so she can take over my village." "I must return the jade Buddha to protect Lanzhou." "Mr. Fogg is the fastest way." "Perhaps, then, we can help one another." "I will keep your secret, and you, you convince Mr. Fogg to allow me to travel the world with you." "Keep this Dummkopf in his seat, or we throw him off!" "Merely pointing out that, uh, if they coordinated their coal-shoveling technique, they could maximize our speed." "When we reach Constantinople, I suggest you board a train we are not on." " Uh, Mr. Fogg, she must come with us." " And why is that?" "Uh, we just discovered that we are related from the same family." "I'm her father's second cousin's sister on my mother's side." "French." "Monsieur Fogg." "If I make the train go faster, I can come with you, oui?" "Yes." "I bid you farewell, Miss La Roche." "If there's anything else you would like, just let us know, Miss La Roche." "Ah!" "Voila." "Champagne with your first-class seats, Mademoiselle La Roche." "Merci." " Champagne?" " No, thank you." " Merci." " Monsieur." "A tea?" "Okay." ""How to make English tea."" "Precisely 96 degrees." "Excuse me, sir." "Fogg's valet!" " A jade Buddha!" " This is not a jade Buddha." " Oh, yes, it is!" " You're right." "But..." "I'm not a valet." "Oh." "Really?" "Me bloody... bloody nose!" "Let me in!" "You're gonna pay for scorching' me willy!" "Heh-heh-heh-heh." "Now I gotcha." "Ow!" "Oh!" "Ow!" "Ahhh!" "You're under arrest!" "Ah!" "Ooh!" "Ow!" "Sorry!" "Why the devil are we stopping?" "Prince Hapi would be honored to have Phileas Fogg and his travelling companions at his banquet." "How very flattering." "But please inform prince "Happy" that we are on a very tight schedule." "Prince Hapi demands it." "Then prince Hapi will have to get accustomed to not getting everything he wants." "It is magnificent." "Mr. Fogg, his house is even bigger than yours." "His collection, his taste..." "It is exquisite." "Yes, it is." "Not good." "Very old." "Look." "Broken." "And where is His Highness?" "Oh." "The prince is also a talented musician." "Sorry if I did nothing but, uh, lounge about the palace all day," "I'd learn to pluck a few notes." "Well, let's make this brief." "I'll pose for a few photographs, perhaps wearing a turban, holding an atlas..." "Mademoiselle." "How magical that our paths should cross." "Do you believe in fate?" "Is that what you call it when one stops a moving train and kidnaps its passengers?" "Phileas Fogg." "Please forgive me, but I feel like Aphrodite herself descended to Earth." "Now, what is a ravishing woman like you..." " I never think when I'm naked." " I do." "In the bath." " Yes." "Well, I mean..." " No!" "Don't touch it!" " That is my most treasured possession." " I was only pointing." "I was just..." "Don't even point." "Rodin." "Yes." "A Rodin." "Oh." "I have never seen a more beautiful..." "muscular form." "Well, I can assure you, I'm in much better shape now." "Incroyable." "It is a sculpture of you!" "Yes." ""Hapi Birthday." "Your pal, Rodin."" " Come, my dear." "Let us dine." " Yes." "Ah, Mr. Fogg, please join us." "No, sorry." "We are on a tight schedule." "We will join you, actually." "But just one drink." "After the duke and the duchess sat down in the bath," "I realized I forgot to put on my bathing suit." "I'm such a fool." "Always embarrassing myself in front of visiting dignitaries." "But you know how that can be, right, Phil?" "Uh, yes." "Uh, it's Phileas, actually." "So, Foggy, tell me." "I heard you're an inventor." "Well, I try to apply myself to thinking of new ways to help better mankind, if that's what you mean." "Well, I'm not an inventor, but I did develop a new way of irrigating dry land so that no one in my kingdom ever has to be hungry." "Oh." "Mr. Fogg invented wheelie shoes." "Not now, Passepartout." "Oh." "Mmm." " Miss La Roche." " Hmm?" "It is mesmerizing, the way your face illuminates." "Oh..." "You know, her discoloration could easily be interpreted as an allergic reaction or a mild form of hives." "Although in actuality I've noticed a certain... luminescent glow about her complexion when she's drawing." "And... sometimes, when she's..." "concentrating on her latest work, her ears will actually flutter." " It's rather fetching." " Well, guess who else was in this bath." "U.S. President Rutherford B. Hayes." "Shouldn't we be going now?" "We have a schedule to keep." "Thank you for your hospitality, prince Hapi." "It's been absolutely fascinating, but I'm... afraid we must push on." "Yes." "Very well." "The gentlemen are free to go." "But Miss La Roche..." "stays here with me." " To be my wife." " Hmm?" "Yes." "Wife number seven." " You have seven wives?" " One for each day of the week." " This is absolutely ridiculous!" " No more talk!" "Prince Hapi has spoken!" "Well, we did say one drink." "Passepartout, we're leaving." "I can tell when we're not wanted." "Monsieur Fogg!" "Do Tuesdays work for you?" " Good-bye." " Thank you!" "No!" "Halt!" "Or Hapi gets smashed!" "Please!" "Anything but my statue of me!" "Miss La Roche, please join us, if you will." " All of you, drop your weapons." " Do as he says!" " Get in the tent." " Everybody!" " Now!" " Let's go." "Come on." "Now, take off your clothes and throw them..." "Uh..." "I assure you the statue is not armed... harmed in any way." "Fact is it's... it's completely..." "Get them!" "His arm!" "Thank you, Phileas." "That was very heroic." "Yes, a-a-and needlessly time-consuming." "This is exactly why I should never have let you come along." "Kill them!" "I want my arm!" "No!" "Sir!" "I've received a telegram from inspector Fix." " A-ha!" " According to him, the bank thief and Fogg's valet are the same man." "That numb-skull Fogg doesn't even realize he's transporting the bank thief!" " Or does he?" " He did leave town in quite a hurry." "Wouldn't you say, Lord Rhodes?" "Indeed, Lord Salisbury." "Eh, evading arrest, stealing a police vehicle, sounds rather incriminating to me." "One can almost deduce this entire bet was merely a ruse to facilitate his escape." " Don't you agree, Lord Kelvin?" " Yes." "Brilliant, Lord Salisbury." "I shall name a beef-related entrée after you in your honor!" "Kitchner!" " Sir!" " Inform your men at Scotland Yard that Phileas Fogg is without a doubt the man who robbed the Bank of England!" " Where are they now?" " Uh, they're taking a train across India, from Bombay to Calcutta." "Thank God we own India!" "I want their faces posted in every police station, army barracks, post office, railway station and outhouse in India!" "We're going to stop Fogg and get my jade Buddha back by any means necessary!" "Agra is where we will capture them!" "Intercept them at Agra!" "Carry on, Cutter!" "Move it!" "Move it!" "Fall in!" "And they were the greatest kung fu boxers." "Ten Tigers of Canton." "Brothers in arms." "They fought to keep order and justice in China." "The most famous of Ten Tigers is Wong Fei Hung." "Armed with only bamboo sticks..." "It's salivating on... please." "Is this your goat?" "Did they really fight like tigers?" "Each Tiger have their own animal fighting style." "Like tiger." "Snake." "Snake head, snake tail, snake mouth, snake tongue!" "Where are my impression calculations?" "Monkey!" "The goat!" "Passepartout, I'm being attacked by a ferocious animal!" " It has... small horns." " Sorry, Mr. Fogg." "Please keep that inconsiderate beast away from me." "And refrain from your ridiculous anecdotes." "Why do you not like his story, Mr. Frog?" "It's Fogg." "Phileas Fogg." "How could a man learn to defend himself by watching animals behave like..." " animals?" " It is famous legend." " A ridiculous legend." " Most legends are born from truth." "Yes." "But all truths are born from facts." "Solid, tangible facts that can be... calculated and... written down on paper." "And then eaten by a goat." "Mr. Feelsillious, when I tell the story of the man who circled the entire world in 80 days, would that not be a legend?" "Only if the man's name was..." "Feelsillious Frog." " What the blazes is it now?" " Come this way!" "Come on!" "Look sharp, now." "Get 'em!" "Find these men!" "Uh-oh." "Time to go." "They seem to think we robbed the Bank of England." "It's preposterous." "This is a desperate attempt by Lord Kelvin to impede my journey." "I am a British citizen." "I have nothing to fear." "Except bullets." "Listen up!" "Have you seen these men?" "Come on!" "Any word on the bank thieves, sir?" "They were spotted on the train." "Keep your rifles at the ready." "They won't get past us, sir!" "Ladies, have you seen these two men?" "Look closely." "They're very dangerous." "They're everywhere!" "This is not going to work!" " Stay calm." "Just act like ladies." " Not a problem." "Hello." "Hello!" "Ah." " I feel faint." " Phileas, women are not that weak!" "No, but I am." "Hello, darlin'." "What can I do for you, eh?" "What nice hand, nice eye, nice hair..." "Hang about!" "Mr. Fogg, what are you doing?" "This is no time to sleep." "Stop, stop, stop, stop." "Go, go, go!" "Get us out of Agra quickly." "Passepartout, we did it." "Hey, wrong way." "Ah!" "Phileas?" "No!" "No!" "Aah!" "Run!" "Run, Passepartout!" "Ah!" "Ah!" "Ahhh!" "Fogg's valet!" "Heh!" " What are you doing?" " Now I gotcha!" "Hand over the jade Buddha!" "Oh!" "You're under arrest!" "Whoa!" "Watch me plums!" "Ooh!" "See?" "Now you get him very mad!" "Let's go." "Stop, or I'll arrest you as well!" "Run!" " Which way?" " Down!" "Again!" "Down!" "Jump!" " Go, go, go, go, go, go!" " What's upsetting him?" " He also wants the jade Buddha!" " Then give it to him!" " Phileas, wake up!" " Please, please." "You must go." "My husband will be home soon." " Phileas!" "Phileas, help!" "Leave her alone!" "I'll protect you!" "Ah!" "I'm here, my dear." "Uh, that, uh, stumble was simply to buy me time." "This cane is not as it appears." "If I depress this button here, it would deploy a weapon far more deadly than yours." "This... is... a... strange knife." "Isn't it a sextant?" "Yes." "Huh." " Are you all right, my dear?" " Phileas, that was so unlike you." "Ah!" "You men, come with me!" "You'd better put this on." "Perhaps I should, uh, wear women's clothing more often." "We should run." " What, now?" " Mm-hmm." "Yes, we should run." " Break down the door!" " Okay." "No, no, no, not me brains!" " Give me the jade Bu-ddhay!" " Okay, okay." "What's "Bu-ddhay"?" "Get ready to jump!" "Now!" "It is him, the Englishman who robbed the Bank of England!" "He's escaping in that palkee-garry!" "Hey, there he is!" "They'll check all trains heading east." "If we could make it to the coast, we can't sail into Singapore or Hong Kong." " They're both British colonies." " Does England own everything in Asia?" "Not China." "Not yet." "Passepartout?" " You look troubled." " I cannot keep lying to Mr. Fogg." "You did what you had to." "The fate of your village is of far greater importance than any bet Phileas has made." "If he loses, all it will cost him is some money and pride." "No, Mr. Fogg will lose much more than that." "What do you mean?" "My village!" " Your village?" " Uh..." "I mean, my, what a village!" "Oh, it's beautiful!" "We do need to stop and resupply, but we must be off by morning." " Lau Xing, Lau Xing." " Lau Xing, Lau Xing." "Lau Xing." " Lau Xing." " Lau Xing." "Goodness, that's quite a welcome." "Do these people know him?" "It must be their custom, the way they welcome all strangers." " Lau Xing." " Lau Xing." "Kids, say hello to my friends as well." "Whoo!" "Lau Xing." "My son, you're home!" "Lau Xing." "Lau Xing." "Who is that man?" "Ah." "Uh..." "He's my valet." "I am so proud of you." "My son has a valet." "How happy I am!" "We must celebrate that Lau Xing returned." "His valet will cook a big feast for us!" "Oh." "It's beautiful." "You are very talented." "Thank you." "You need more blue." "Fascinating." "Absolutely fascinating." "Sorry?" "Vile." "Absolutely vile." "Welcome home, Lau Xing." "Your brothers will be proud." "The whole notion of a lighter-than-air craft cannot work, of course, unless you can harness the power of... helium... or hydrogen, which is far better..." "Yes, well, couldn't have put it better myself." "As for this Englishman, do you think such an association is wise?" "I promise you, he is the most disciplined man I have ever met." "The crane!" "The monkey." "Very frightening." "Snake." "And, of course, the eagle." "Phileas?" "Phileas, I made this for you." "Oh, yes." "Oh, that's very, very good." "Yes." "What does this say?" "Stupid." "You have returned our sacred Buddha." "It has brought hope back to our village." "Drink!" "Thanks to your courageous efforts..." "Drink!" "I've had quite enough." "I just..." "I..." "Thanks to your courageous efforts... we will live in peace and..." "Drink!" "Thanks to your courageous efforts... we will live in peace and harmony... and for that we are eternally grateful!" "Drink!" "I'm going to be abominably ill." "Drink!" "I..." "I want to die." "Please kill me." ""Dear father:" "I will find the fastest way to China."" "It's strong." "Mr. Fogg, I was going to tell you." " This is your family." " My name is not Passepartout." "It is Lau Xing." " I robbed the Bank of England." " You robbed the Bank of England?" "Not for gold or money, but for the jade Buddha." "It was stolen from our village." "Phileas, he had no other choice." "This was his only way to get home." " You knew about this?" " Well..." "I have nothing but respect for you, Mr. Fogg." "Then respect my deductive reasoning." "You have both used me." "You to escape to China, and you to travel the world to further your impressionistic humbug!" "Your overtures of..." "comradeship, of friendship, of..." "All that was just a means to ensure I would take you along." "My entire life, I got along splendidly by myself." "You've been nothing more than pebbles in my shoe, slowing me down, endangering my life, risking everything, all I've ever lived for." "And you!" "You knew that." "Don't let him go." "He'll be lost by midnight." "Go!" "More of your relatives, I suppose." "You can just forget about a reference." "I beg a thousand pardons, Mr. Fogg." "What's he screaming about?" "He's saying "Please, let me go." "I'm bored."" "Why is he in prison?" "Urinating in public." "Charming." "At least he had the decency to be forthcoming about it." "Is there anything you've told me that's even remotely true?" "I really can sing." "Look!" "Oh, good." "Here comes Mr. Grumpy and the Leatherettes." " Where is the jade Buddha?" " You are better off killing me." "You have nerve." "Are your comrades so brave?" "Your threats don't frighten me." "Nor does your silly bracelet." "All right." "It's not silly." "I spit on you!" "France spits on you!" "Vive L'Anjou!" " Your turn will come soon enough." " Coward!" "Leave them alone." "Fight me." "Yes, fight him." "Let's see how ferocious you really are." "Hey, that's cheating!" " Look out!" " Huh?" "Left!" "Behind you!" "No!" " Hit them!" " Silence!" "You savages!" "Phileas, help him!" " Watch out on the right." " Huh?" "No, no, my right." "Stop helping me!" "Sorry." "What's happening?" "Where is Passepartout?" "How is he getting on?" "I wouldn't say he's winning, but, uh, I think he's doing all right." "Go home to mama." " What took you so long?" " I had to finish my lunch." "Wong Fei Hung!" "Surely you're not foolish enough to take on all of my men by yourself?" "Ten Tigers?" "Kill them!" "Execute the prisoners!" "I want their heads on pikes!" "What's happening?" "Phileas!" "Passepartout..." "Knife!" " Merci." " Oh, you're welcome." "You promise me that Black Scorpions will never come back to Lanzhou." "These are my brothers and sister." "The Ten Tigers." " But there are only nine." " Including me." "They're real." "The legend was true." " Mr. Fogg..." " Passepartout, or whatever your name is, save your apologies." "Phileas, he risked his life for what he believes in." "If anyone understands that, you do." "Please ensure Miss La Roche finds safe passage home." "This should be adequate." "Oh." "I, uh, believe this is your veil." "I will never dress like a woman again." "Ever." "Mr. Fogg." "Please let me help you win your bet." "I have secured the services of a more reliable gentleman." "Give me a minute." "You never learn!" "Yes." "Well, perhaps I'll just, uh, travel alone." "Fifi La Belle!" "She sings!" "She dances!" "She does the dance of the..." "You, sir, come right in." "See Miss Fifi La Belle in all her..." "Ah, the most modern city in the world." "Finally, civilization." "Excuse me." "Pardon me." "Eh, can anyone direct me to the Pacific Railroad Station?" "Oh, I'm so sorry, sir." "I'm such a... rutabaga sometimes." "No, no, no." "Please, it's... my fault entirely." " Let me, uh..." " Oh..." "Ah!" "Oh." "Oh, Lord, I think I sprained my knee." "Uh!" "Ooh." "I should, uh, find you a physician." "There's a kind old doctor who has an office just around the corner." "Excellent." "Well, uh, I-I'll get him for you." "Thank you." "There should be more people like you in this world." "Whoo, doggy!" "Jackpot!" "Whoo!" "Three days later." "Mon Dieu." "Can you imagine Phileas alone in a place like this?" "I'm sure he's fine." "Alms." "Alms." "Alms for the poor?" "Arms?" "You already got arms." "It's money you need." "I can't even scrounge proficiently." "Hey." "Cheer up, pal." "You just gotta figure out what'll work for you." "Now, what makes you different from them?" "I'm hungry and miserable." "No." "You stink." "Now, your stink is your most powerful weapon in your begging arsenal." "Watch this." "Hey." " Gimme some money, please." " Yeah, sure, pal." "Just don't touch me." "You stink." " That guy smells like a dead horse!" " I'm not proud of it." "Simple... yet effective." " Yeah, I see." " You try." "Come on, give it a shot." "I got faith in you." "Excuse me." "Now, uh, you..." "I'm not gonna lie to you." "That's gonna happen about half the time." "It's a volume business." " Hunk o' cheese?" " Oh, yes, I would rather..." "Maybe later." "What are them drawings?" "You some kind of devil worshipper?" "Don't you be putting a hex on me." "I'll cut you." " I'm an inventor." " That's nice." "Or, rather, I was." "One day I will build a machine that will allow man to fly." "Flying men?" "Where?" " Nowhere." " Where are the flying men?" " Where are the flying men?" " They're over there." "The bird men are coming!" "I knew it!" "The bird men are coming!" "The bird men are coming!" "The birds!" "The bird men!" "Bird men!" "Birds!" ""I travelled the world for inspiration and found it in a man..." "who lives what he dreams."" " Phileas?" " No." "Passepartout!" "Monique!" "Mr. Fogg." "You crossed the Pacific Ocean." "For me?" " We will help you win your bet." " Mr. Fogg, I would never let you down." " But why would you do this?" " Because you are our friend, and perhaps... more." "More with her." "You and me?" "We just stick with friends." "Lord Kelvin, I can offer you something much more precious than a single jade Buddha." "Beneath Lanzhou are a series of untapped jade reserves." "If the town were to be overrun, those reserves would be ours." "I see." "However, should Phileas Fogg win this race," "I will have neither the power nor the means to hand over any arsenal." "Then I will see to it personally that Mr. Fogg's journey is cut... short." "Very well." "Let us consider our deal to be..." "Still, i-it's a first-rate idea, sir." "What's this thing here blocking my jade reserves?" "That will certainly have to be demolished." "But that is the Great Wall of China, sir." "It's not that great." "Passepartout went to get help hours ago." "What if he's lost, or..." "Don't fret, my dear." "No doubt he'll return with help, and we will board our train in Reno with time to spare." "Agua." "Perhaps I'm being a little optimistic." "Help!" " Help us!" " Help!" "Ah!" "A rattlesnake!" "Help!" "I don't want to die!" "Ah." "Good morning." " Howdy." " Hey." "Crazy English cowboy wannabe man." "How's about going and be crazy someplace else?" "You're blocking the damn path." "Wilbur, it's him." "I'll be damned." "Mr. Fogg, my name is Orville Wright." "This is my brother, Wilbur." " We're big fans of yours." " Well, fan's a strong word." "Better way to say it's we got a lot of money riding on you to win your bet." "And when you win it, we're gonna use our winnings to build this." "Orville, maybe now is not the time." "Let me explain it to Mr. Fogg." "Mr. Fogg, just one second." "You gotta forgive my brother." "He's got his head up in the clouds." "He's one of these sad old dreamers who..." "thinks man's gonna go swooshing around on the planet like a little hummingbird flying through the air." "Yeah, we're all gonna fly, bro." "He thinks so, too." "It's really kind of sad." "I'm sorry." "He's kind of a moron." "He's mastered the cable steering system." "I knew it." "The-the-the drag-and-lift ratio." " This is brilliant." " Thank you." "That's what I've been saying, but Orville doesn't listen to me." "All that stuff you said about mastering..." "That's-that's exactly what I say." "You gotta have faith in me, no matter how crazy big brother's dreams sound." " But you told me..." " You gotta have confidence." "Shh." " I said you gotta speak up and support me." " Excuse me, gentlemen." "Have you come across our friend on your way here?" "Now, wait, wait." "Who are we looking for?" "I notice everything." "Passepartout." "You mean the crazy, half-naked Chinese guy we saw running around, where he was like..." " Singing "Frere Jacques"?" " Yeah, and a cow skull on his head?" " Possibly." " Yes." " He's in the back of the wagon." " Passepartout." " You're alive!" " Is that you, grandma?" " Bye-bye." " Good luck." "Go win the bet." " No pressure, but you gotta win it." " Bye." "Now, you see, to get the real classy dames, you gotta invent stuff." "I did." ""I did"?" "What's with the "I did"?" "We're the Wright Brothers." "We did." "Now go." "Hyah!" "They're not going to make it!" "They're not going to make it!" "Ah-ha-ha!" "New York, New York!" "So much to see!" "So little time!" "Our steamer for London leaves in ten minutes!" "Go, go, go!" "Go, go, go!" " We're never going to make it." " Phileas Fogg?" "Would you autograph this for me, please?" "It's for the wife." "Certainly." "Uh, this business about me..." "robbing the Bank of England..." "Ah, I'm from Ireland." "Nice goin'." "The boat." "Right." "Come on, follow me." "I know a shortcut." "Make a lane!" "Make a lane!" "Where are we?" " Ah!" " Whoa!" " That's a big man." " It is a lady." "A French lady." "She looks like an evil Chinese warlord to me." "Your journey has caused quite a stir, Mr. Fogg, but I'm afraid it ends here." "Leave them alone, Fang." "This has nothing to do with them." "On the contrary, Lau Xing," "Lord Kelvin and I have made new arrangements to conquer Lanzhou." "Unfortunately for Mr. Fogg, they entail his..." "permanent detour." "I knew Kelvin was duplicitous, but to align himself with such a little scoundrel!" "All right, you're not a scoundrel, but you are quite small!" "As in... petite, but most definitely lethal and, you know, generally very scary." "One, two..." " Go!" " Three!" " Go up there." " Stop them." "Passepartout, my cane!" "Uh, there." "Passepartout!" "Help!" "We are trapped!" "Help!" "Passepartout!" "Help!" "There you are!" "You have a knife in your right buttock." "It's the evil Chinese warlord!" " Ooh!" " Huh?" "She's coming!" "The boat!" "Up there!" "Hurry!" "Go, go, go!" "Go, Mr. Fogg." "There's not much time." "Ah, wait, wait!" "What am I thinking?" "Passepartout can't defeat them all by himself." "He's... nine Tigers short." "Phileas, I do believe you are becoming the man of my dreams." "Well, when this is over, let's hope that, uh, the arms and legs of the man of your dreams are still attached to the torso... of the man of your dreams." " You have failed to stop him." " Then your death will have to suffice." "Let go of me!" "The book!" "It's going to fall!" "How can we save..." " Phileas?" " I will save him..." "Wah!" "Mr. Fogg!" "No!" "Passepartout?" "Passepartout!" " Huh?" " You're alive!" "Are you injured?" "Yes, well, uh..." "Rules are made to be broken." "Or, uh, stabbed by a... spiky shoe." "Mr. Fogg, you missed the ship." "You'll lose your bet." "Oh." "At least I didn't lose a friend." "You must be the eleventh Tiger." "Meow!" " Let's go." "We must catch the next ship." " It would never reach London in time." "No." "No!" "No!" "We are not giving up!" "I almost died!" "You almost died!" "We take the next ship and win that bet!" "Very well." " Let's go." " Yes!" "Thank you." "Yes." "Yes!" "Yes!" "Oh, it's hopeless." "By those calculations, I'm still behind by one day." " Phileas, there must be some way!" " Phileas Fogg on my boat?" "What an honor, sir!" "I've quite a penny wagered on you." "The wife's none too happy about it." "Then again, she hasn't cracked a smile since the day that shark almost devoured me." "Got 'em both in one bite." "Ah, it's inspector Fix!" "My goodness!" "He made it around the world before Fogg!" "I came back from India the short way, you ninny!" "I take it you don't have Phileas Fogg in that valise." "A little jade Buddha, perhaps?" "That's the last of the coal, captain." "Mr. Fogg." "I'm sorry to say, we've burnt the last of the coal." "But I've had a word with the crew, and all of them... have agreed to burn their shoes." "The effort is appreciated, captain." "Unfortunately, we're not even close." "We've gained a mere six hours." " Even shoes cannot help us now." " Must be something we can do." "That's it." "I've got it." "Birds." "Excellent idea!" "We'll burn birds!" "No, we'll fly to London." "We simply follow the laws of physics mastered by the birds millennia ago and combine it with the Wright Brothers' ingenious cable steering system." "Most people would laugh at you." "But not us." "We care about you." "Captain, I'm afraid I have to ask permission to dismantle your ship to build this flying machine." "Dismantle "Carmen"?" "But she's me livelihood, me most loyal companion." "Never, never, ever!" "What if I could direct you to an impeccable physician who could replace both your nipples, at my expense, and I will give you enough money to buy a brand-new ship?" "You had me at the nipples." " Cornelius, fetch me me tools!" "Now!" " Aye, aye, captain!" "One, two!" "One, two!" "Timber!" "I'll go sharpen the propeller." "Wrong way." "Not looking." "Just one more." "That's it!" "Right, lads, tie it off!" "The Greenwich time zone." "The last time I shall set my watch ahead." "Well..." " Shall we... fly?" " Let's." "Mr. Fogg." "Hurrah!" "Inspiring words." " Very well." "Prepare for take-off!" " Yes, sir!" " Mr. Fogg, are you sure?" " No!" "Whoa!" "How the hell are we getting back?" "Whoa!" " Now!" " Ohhh!" "You did it, Phileas!" "We are flying!" "My God!" "It's... magical!" " Better than your dreams?" " Better than my dreams." "Hey!" "Don't forget to steer!" "It's a... a... telegram from... general Fang, sir." "We're going to make it!" " This all right?" " Oh, dear." " This is exactly like a dream I had." " You dream of winning the race?" " No, of crashing to my death." " Don't worry." "I'm gonna get it." " Look up there!" " Great Scott!" "Look, look!" "It's a flying machine!" " Don't step on the wing!" " It's Phileas Fogg!" "Sir, rumor has it a flying machine is heading for the Royal Academy, our bank thief at the pedals." "Some people will believe anything." "A flying machine is heading for the Royal Academy!" " The bank thief is pedaling!" " See what I mean?" "Help!" "Well done, Passepartout!" "The wing ropes!" "Just a minor setback." "Another minor setback." "All right, this is a major setback." "A flying machine is headed for the Royal Academy of Science, and witnesses swear that it's..." "Phileas Fogg." "Faster, Passepartout!" "Faster!" " We're losing altitude!" " Landing gear?" "That would have been an excellent idea!" "The bird men are here!" "No." "I will not lose this wager!" "He is not to reach the top step." "Get the police." "Here." "Now!" "I want Phileas Fogg arrested the moment his feet touch British soil!" "Oh!" " I'm sorry..." " Right in my ear!" "Passepartout, get back in your seat." "We're going to return to the ground!" "Stop!" "Kitchner!" "Hold your ground!" "Why are they all fleeing?" "Cowards!" "Hold on!" "We're to make it to the top step!" " Ah." "New Zealand." "We didn't go there." " Top step." "Arrest them!" "They robbed the Bank of England!" "No, no!" "Nonsense!" "Where is your proof?" "This is the Royal Academy of Science!" "We don't need to prove anything!" "Besides which, by the time you get out of jail, you'll have lost the wager." "Noon." "We did our best." "Out of me way!" "Move it!" "I used to be somebody important!" "Should have thrown him through a higher window." " Get off!" " Get rid of this buffoon!" " Buffoon, eh?" "That's the thanks I get for going halfway around the world to stop Fogg for you, yay?" "He also sent a Chinese warlord to kill Phileas Fogg!" "That's right." "He did!" "Lies!" "All of it!" " Kitchner!" " Yes?" " Tell them!" " Oh, well, yes, uh..." " Well, the thing of it..." " You mumbling moron!" "Salisbury, please translate Kitchner's incoherent blather." "I..." "Me..." "I..." "Yes." "Yes!" " Rhodes!" " The-the thing of it is," "I don't want to make a fuss." "You spineless cretins!" "That man stuck me with quills!" "Bunches of them!" "Yes!" "Lord Kelvin's a bully!" "It's true!" "I hate to admit it, but I'm a battered lord." " No!" " Oh, boo-hoo!" "So what if I did try to kill Phileas Fogg?" "What are you... gutless peons going to do about it?" "I hold all the power!" "I run everything!" "So, which of you half-wits is going to stop me?" "You?" "You?" "You?" " The queen!" " The queen?" "Oh, the queen!" "That inbred, antiquated old cow!" "The only way she could stop me is if she sat on me!" "With her big, fat royal bottom!" "She's behind me, isn't she?" "Oh, Your Majesty." "I have just apprehended the culprits who robbed the Bank of England." " No, Majesty!" " Rubbish!" "Quiet!" "I love being able to do that." "So, Lord Kelvin, unsportsmanlike conduct, attempted murder, trading my arsenal for Buddhas." "How do you know about that?" "I never said..." "Admit it." "You've been a naughty boy, haven't you?" "Your Majesty, I assure you, there is an explanation for all of this." "What it was, was, was..." "I was..." "I..." "I was simply... simply..." "Why do they always run?" "Arrest him." "Get out of my way, you fools!" "Unhand me!" "Don't you know who I am?" "I'll kill you!" "I'll have you for this, Fogg!" "So, is this Phileas Fogg's miraculous flying invention?" "Your Majesty, we all invented it." "I'm very impressed, and that doesn't happen often." "Thank you." "But still, we failed to help Phileas win his bet." " I'm sorry, Phileas." " Don't be, ma chérie." "I saw the world." "I learnt of new cultures." "I flew across an ocean." "I wore women's clothing." "Oh?" "Made a friend." "Fell in love." " Who cares if I lost a wager?" " I do." "I've got 20 quid riding on you." "But, Your Majesty, it is gone 12 noon." "Correct." "Which gives you 24 hours remaining." " Could we have miscounted?" " No." "I moved Mr. Fogg's watch ahead one hour as we passed each time zone." "The international date line." "We set our watches forward at 20 more time zones, so... here it's still... day 79." " So, we've..." " We've won!" "We won, we won..." "Thank God." "Ah!" "Your Majesty, I..." "I apologize." "Do forgive me." "I, uh..." " I quite forgot myself." " Go and win your bet, Mr. Fogg." "I shall need a new minister of science." "Uh, yes, of course, Your Majesty." " Shall we?" " Yeah." "Go!" " We won, Phileas!" "We won!" " Yes!" "We won!" "Oh, well done!" | Mid | [
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[Multimodal evoked potentials and central mechanisms of afferentation in trigeminal neuralgia]. Multimodal evoked potentials in patients with trigeminal neuralgia are analyzed in the paper. The comprehensive studies of cortical trigeminal somatosensory evoked potentials, visual evoked potentials, and brainstem auditory evoked potentials have revealed their changes that are indicative of the impaired central mechanisms of afferentation in patients with trigeminal abnormality. The findings are discussed in the light of the theory of generator mechanisms of neuropathological pain syndromes. | High | [
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<!-- ~ Copyright (c) 2016-2020 VMware, Inc. ~ All Rights ReserveThis software is released under MIT license. ~ The full license information can be found in LICENSE in the root directory of this project. --> <div class="main-container"> <div class="content-container"> <div class="content-area"> <h1>Checkbox demo</h1> <form clrForm (ngSubmit)="onSubmit(form.value)" #form="ngForm"> <clr-checkbox-container [clrInline]="inline"> <label>Basic Checkbox</label> <clr-checkbox-wrapper> <input type="checkbox" clrCheckbox name="model" [(ngModel)]="option1" [required]="required" [disabled]="disabled" /> <label>Option 1</label> </clr-checkbox-wrapper> <clr-checkbox-wrapper> <input type="checkbox" clrCheckbox name="model" [(ngModel)]="option2" [disabled]="disabled" /> <label>Option 2</label> </clr-checkbox-wrapper> <clr-control-helper *ngIf="helper">Helper text.</clr-control-helper> <clr-control-error *ngIf="error">There is an error.</clr-control-error> </clr-checkbox-container> <section> <button class="btn btn-success">Submit</button> </section> </form> </div> </div> </div> | Low | [
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Q: Intertwining 3 arrays in matlab / octave to get correct pattern I know I can intertwine 2 arrays by C = [A(:),B(:)].'; %' D = C(:) But how can I intertwine 3 arrays with a (pendulum type of pattern going back and forth) See image below with arrows showing the intertwining path pattern I'm trying to get (each column is an array). Also the number pattern I'm trying to get is also next to it, in one large column. Please note the numerical values are just examples to make it easier to read. the numerical values could be decimals also I tried the code below but the pattern is incorrect. A=[1,2,3,4,5] B=[10,20,30,40,50,60,70,80,90] C=[100,200,300,400,500] D = [A(:),B(:),C(:)].'; %' E = D(:) I get an error in the D array due to the fact that the B array is a larger size than A and C but the number pattern is also not following the pattern I'm trying to get. 1 10 100 2 20 200 3 30 300 4 40 400 5 50 500 error: horizontal dimensions mismatch (5x1 vs 9x1) The pattern from the 3 arrays I'm trying to get is below. Please note the numerical values are just examples to make it easier to read. the numerical values could be decimals also 1 10 100 20 2 30 200 40 3 50 300 60 4 70 400 80 5 90 500 PS: I'm using Octave 3.8.1 which is like matlab A: Have you tried the following? D = zeros(4 * size(A, 2) - 1, 1); % initialization D(1 : 4 : end) = A; D(2 : 2 : end) = B; D(3 : 4 : end) = C; | Mid | [
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Ricky Meggison and Angel Sanfilippo don't seem like a power couple. But what comes out of their kitchen and into their clean, humbly decorated dining room at Dominion and Academy says otherwise. They're the owners — and, currently, sole employees — of Rock City Café, both veterans of venerated downtown diner King's Chef. Their restaurant has a short but busy history, so here's a quick recap: Local radio personality Aaron "Goose" Seller started Rock City Sliders and Coneys as a love letter to Detroit in a shopping center at Union and Boulder at the end of 2014. In fall of 2015, he sold the spot to Meggison and Sanfilippo, who kept the sliders and coneys but introduced a full breakfast and lunch menu, changing the name to Rock City Café. The next year, in September, they closed the 15-seat café, and the shopping center was demolished to make way for a Starbucks. On April 11, Meggison and Sanfilippo reopened Rock City Café in its current spot, expanding to 35 seats. And in terms of quality, they haven't missed a beat. Let's talk french fries. Theirs are cut fresh in-house, seasoned with salt and pepper. There's no grease taste or mouthfeel — diners can still tell that the fries came from a potato. The texture's perfect, a little chew, a little tender, and an occasional crunch. And they're cooked uniformly, too. Fingerling potatoes dream of becoming fries like this when they grow up. Fresh continues throughout most of what we sample from the menu. The Rock City peppers, a signature from the always-available breakfast menu, consist of a halved bell pepper stuffed with cubed potatoes, scrambled eggs, cheese and choice of ham, bacon or sausage, smothered in house-made green chile. What should be a paralytic gut bomb isn't — the pepper's just cooked through, the potatoes come fresh as the fries and again, it's not at all greasy. That chile adds a pleasant level of spice and tomato brightness, too, and the heat doesn't build up, so it's accessible. For a more East Coast option, the corned beef hash sees fresh potatoes and peppers mixed with bits of lunchmeat-thin corned beef, under two eggs. Either satisfies with a cup of diner-done-right coffee from Elevation Coffee Traders. Per the menu, all burgers come cooked through, but my beach bum burger has enough fat that it's at least not dry. Avocado, bacon, Swiss cheese and ranch play well with the half-pound patty. Staggeringly, it's pretty light for the sheer amount of meat and fat in play — such a dish would usually have me thinking naptime, but not so here. Hot dogs also satisfy. We go for the Reuben dog, topped with Swiss, kraut and Thousand Island dressing. The sausage lacks snap, but the almost-creamy texture satisfies in its own way. But for old-incarnation holdovers, it's all about the sliders, meaty and delicious with black pepper, grilled onions and nothing else. Cheese is genuinely optional. There's cheaper in town — most plates here land around $10, though it's easy to fill up on dogs or sliders for less — but most of it isn't this good. And it's hard to find diner food that goes down this lightly. If Meggison and Sanfilippo take any shortcuts, they're hard to find. For those who still wonder why big-name chefs enjoy simple meals made with fresh ingredients, prepared with precision, drop by. You'll understand. | Mid | [
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The visionary urban planner chosen by Mayor Lori Lightfoot to lead the Chicago Department of Transportation on Tuesday embraced the red-light camera program that motorists love to hate, saying Chicago has turned the page from a $2 million bribery scandal. Suburban red-light cameras are caught up in a still-unfolding federal corruption scandal. Illinois Comptroller Susana Mendoza declared this week she would stop helping suburbs collect those revenues. But Gia Biagi told aldermen at her confirmation hearing that Chicago’s 300 red-light cameras have served their purpose in improving driver safety and must remain in place. “Both red-light and speed zone indicators — through a study we did with Northwestern, I think, in 2017 — we know that they are a deterrent. Speeds do reduce [by] anywhere from 10% to 11%, particularly in areas around parks and schools,” Biagi told the City Council’s Transportation Committee. “On the corruption side, we feel like we’ve reformed our program and think it’s pretty tight. But we’ll take a look at it and make sure that everything’s kosher.” So, Biagi sees no need to revisit the entire program built on a $2 million bribery scandal that paid a convicted city bureaucrat $2,000 for every additional intersection? “We definitely looked at it recently. Of course, we’ll take this opportunity to look again. But, we think we’re in pretty good shape,” the $174,588-a-year commissioner said. Mayor Lori Lightfoot campaigned on a promise to audit the city’s network of red-light cameras and “sunset those cameras that are only being used for revenue — not safety.” Biagi reconciled her defense of red-light cameras with Lightfoot’s campaign promise by pointing to that $311,778 study by Northwestern University’s Traffic Center that charted a path forward for the widely-despised program. Northwestern recommended — and the city agreed — to triple the “grace period” to three-tenths of a second for Chicago motorists caught on camera blowing through red lights. The city did that even though the longer grace period could mean a 29% drop in the number of $100 tickets issued. The city also agreed to begin relocating cameras from six existing intersections to five others where the study showed red-light cameras would have a greater impact on safety. Going forward, the study recommended a “tool to evaluate” red-light camera intersections “with a grade from A-to-D” based on a series of factors, including the trend of violations and traffic crashes. The 105-page study also recommended that the widely-despised program continue because of “significant safety benefits” that include: a 19% reduction in “serious side-angle and turning crashes”; a 10% reduction in “injury-producing” crashes and a “measurable spillover effect” that improved safety, even at intersections without red-light cameras. “It wasn’t us saying this. It was Northwestern looking at the program and saying, `Yes, they’re a deterrent,’ “ Biagi said. “But ... it’s complicated. We need to be working closely locally with folks about where they ought to go and paying attention to what the mayor is saying about making sure that we’re not putting cameras that are unduly a burden on residents.” Biagi takes the reins at CDOT one day after Chicago started implementing a $40 million congestion fee that tripled the tax on ride-hailing passengers traveling solo to and from downtown and slapped a 74% increase on ride-hailing trips in Chicago neighborhoods that go nowhere near downtown. The initial steps will tide the city over pending a long-term study on how a more complicated and broader London-style congestion fee might work in Chicago. The new commissioner was asked what the next generation of Chicago’s congestion fee should look like. “A lot of cities are looking at this. You look at, on one end, what Paris is doing. They’re looking at delivery trucks. You have other models in Stockholm and Singapore,” Biagi said. “We want to make sure what we do is right for Chicago — not just cut-and-paste from somewhere else. That’s why we do need to study it and decide, are other vehicles part of this? Is there a different way to think about it? What’s the right geography?” Yet another focus for Biagi will be reversing the precipitous decline in CTA bus ridership — triggered, in part, by population losses — by increasing speedier bus options beyond LoopLink and Jeffrey Jump so buses become what she called the “first, best option.” “Looking at where we can put in these bus priority zones. Making it as efficient as possible. It’s absolutely critical — especially for places that aren’t as close to a major transportation node, like a train station,” she said. “It’s definitely an important pillar of this administration. To make sure that we have the best bus system in the world. And part of that is having bus priority zones that make it quicker and reliable. That’s what will enable people to want to use it.” | Mid | [
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Bringing you a roundup of WAX news updates over the last few weeks! WAX Newsletter Firstly, WAX is starting a newsletter to keep the community updated on all things WAX. If you’ve previously received emails from WAX, you’re already on the list. Otherwise, you can sign up at https://wax.io/ There, you’ll have an opportunity to tell us what you want to learn about our project in our newsletters so that we can tailor content to best fit the community’s interests. Sign up for the WAX newsletter at wax.io WAX at the Davos World Economic Forum WAX CEO William Quigley presented at a cryptocurrency event adjacent to the World Economic Forum in Davos, Switzerland in January. William Quigley, CEO of WAX, presenting at a crypto event adjacent to the WEF in Davos WAX Partners with Robot Cache In our latest news update, WAX announced a strategic alliance with Robot Cache! This relationship is intended to benefit game publishers and developers, as well as gamers. Previously, gamers were limited to reselling physical copies of a video game. However they can now resell digital games purchased on the Robot Cache platform, using the blockchain, and retain 25% of the proceeds, with developers and publishers earning 70%. Selling digital games earns IRON, Robot Cache’s cryptocurrency, which can be mined or used towards the purchase of another platform game. “Once publishers and gamers realize the benefit of reduced costs and ease of use to acquire games using WAX on Robot Cache, the industry will never be the same,” says WAX President Malcolm CasSelle. On the Robot Cache team is Brian Fargo — Founder of Interplay Entertainment & inXile Entertainment — who is also an advisor to WAX. There will also be an airdrop of IRON to holders of WAX. Details to follow, stay tuned! WAX Sponsors and Presents at TNABC WAX was a gold sponsor at The North American Bitcoin Conference in Miami, FL in January, where President Malcolm CasSelle presented the scope of the in-game digital items trading market and WAX’s use case to thousands of attendees. View the presentation here: WAX also had a booth where the team met many of our supporters (thanks guys!), educated attendees, and gave away lots of WAX swag (which you can now purchase here!) Arielle Brechisci, Special Projects Manager for WAX, talking WAX with attendees at TNABC Miami Also coming out of TNABC, an interview with CryptoCanucks: https://www.youtube.com/watch?v=zMOhVL_Cq6o&feature=youtu.be WAX at the Kyber Network Developer Competition in Seoul WAX was invited to participate a developer competition sponsored by our partners at Kyber Networks in Seoul, South Korea. Brent Cohen, WAX’s Head of Product, joined Kyber’s Loi Luu (CEO), TN Lee (Head of Business Development) and others from their management team at this event. Also sponsoring the event was Simon Kim (CEO) and his team at #Hashed. #Hashed has been active supporters of both WAX and Kyber. Meet-ups like this draw crypto enthusiasts by the hundreds across South Korea and this event was no exception. Five teams from local colleges had been selected to present business ideas that incorporate the Kyber Network. The grand prize winner took home $30,000! After a few days of meetings in Seoul, it was clear that Koreans are extremely interested in and supportive of blockchain projects like WAX and Kyber. This has led to a “Kimchi premium” (Koreans pay more for crypto there than in other countries) which has the government worried that there is overheated interest (e.g., speculation) in this unregulated space. Simon from #Hashed is a frequent commentator on blockchain and crypto issues. He believes that his country’s government wants to be a global leader in the efforts to regulate crypto. First step, announced after Brent left Korea, is to require Korean exchanges to use real name registrations for their customers. There is also a great deal of discussion from the crypto industry about their need to sit down regularly with lawmakers and regulators to discuss shared concerns. Industry leaders are now openly calling for “some” regulation to weed out bad actors and to help the crypto sector grow in Korea. The WAX team left Seoul with a better understanding of the blockchain ecosystem in Korea. We will be back soon! Brent Cohen, Head of Product for WAX, at the Kyber Network Developers Conference in Seoul WAX Partners with Cointopia WAX has partnered with Cointopia, a community-driven token sale marketplace that facilitates secure and successful token sales by connecting ICO companies with the right investors and service providers, to leverage products and services on the WAX platform. Read the press release here. WAX Partners with GIFTO WAX announced a partnership with GIFTO to allow virtual gifts to be tradable on the WAX platform. Read the press release here. WAXing Lyrical CryptoCoin.News interviews WAX President Malcolm CasSelle about WAX and its expected impact on the gaming industry. Read the full interview here. WAX Partners with SALT Lending WAX announced a partnership with SALT Lending, where users will soon be able to use WAX Tokens as collateral for cash loans. WAX holders will be able to keep their cryptocurrency assets, such as gaming skins and crypto collectibles, while accessing cash loans on the SALT platform. Read the press release here. OPSkins in the News A marketplace record was set this week on OPSkins, where a digital gun sold for a whopping $61,052.63 — the highest officially-recorded skin sale ever. Polygon covers the sale, including what made this item nearly as valuable as a 2018 BMW M3, here. An item sold on OPSkins this week for more than $60,000 USD As you know, OPSkins is a sister company to WAX and is the world’s largest marketplace for trading in-game items such as that one. WAX is specifically designed to make it faster, cheaper, and easier to trade these items for all parties involved — including buyers, sellers, marketplaces, affiliates, appraisers, listing sites, etc. By decentralizing this market and lifting the existing barriers to entry off this $50 billion industry, we anticipate WAX will help the in-game virtual trading market reach it’s full potential and grow to nearly double it’s current size. | Mid | [
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SMH: Direct RF Sampling with High Performance ADC Previously analog-to-digital converters (ADC) at high input frequencies were limited in usefulness due to distortion and noise performance. Today, however, ADCs can provide nearly 9.5 bits of effective number of bits (ENOB) at radio frequencies (RF) of 1 GHz with signal bandwidths greater than 200MHz. Such performance at high frequencies eliminates a mixer stage, simplifying receiver design to improve overall system performance. Until now, the only way to capture up to ~200MHz of bandwidth and achieve ENOB values greater than nine bits was to use a receive architecture that down-converted the RF to an IF (intermediate frequency) of less than 750MHz. While this is a fairly high frequency for an ADC, it is not high enough to eliminate a mixing stage in some applications. The elimination of an IF mixing stage helps in many ways. Mixing stages have an adverse affect by adding power consumption, heat, board space, cost, noise and distortion. Figure 1 offers a glimpse of ENOB versus input frequency for today’s best converters capable of capturing at least 200MHz (values estimated from device datasheets). Challenges of VSWRIn a receiver, RF components must carefully match impedances to maintain acceptable voltage standing wave ratio (VSWR) values that do not cause the loss of too much signal due to transmission line reflections. This is true whether driving a mixing stage or an ADC. If the impedances of the driving circuit and load circuit cannot be sufficiently matched at high frequency, the driving circuit may not be able to drive the load and still maintain an acceptable signal level at the load. Ideally, the VSWR should be a ratio of 1:1. That is, all of the power transmitted to the load is absorbed by the load, with no reflection of energy. In reality, this never happens. Most RF designers hope to obtain VSWR values <1.5:1 in actual board design. The higher the ratio, the more power the driver will need in order to maintain the same effective signal level at the load. Distortion out of the amplifier usually increases with an increase in signal level, so compensating for bad VSWR with high drive levels from the driving amplifier could corrupt the signal chain. Typically at high frequency, an ADC’s inputs are driven ac-coupled through a transformer or balun after the signal has passed through a band-pass filter (to eliminate signal aliasing from unwanted Nyquist-bands). To perform a computer simulation of the load impedance presented by the ADC, include the balun, band-pass filter, the source impedance of the driving amplifier, and board parasitics in the simulation. The computer simulation is a good start to understanding the impedance of the total load at the frequency of interest. Input circuits should be high impedance so that the parallel impedance interaction between the external circuitry and the internal circuitry will not create impedance so low it cannot be driven efficiently. High input impedance provides maximum flexibility to the circuitry outside the ADC. If the ADC does not have an integrated high-impedance input buffer, it becomes nearly impossible to drive it at high frequencies while maintaining reasonable distortion from the driver amplifier. Without the integrated input buffer, the ADC input impedance at high frequency is often so low it becomes unacceptable and the amplifier cannot keep up without insufficient performance or extremely high power. The ADC input impedance will be low without an integrated buffer amplifier because the driving circuit most likely will see the sampling-capacitor of the ADC, which has low impedance at high frequencies. For this reason, it is common for an ADC to have an integrated input buffer when designed for use at these frequencies. Even with the buffer, the task is still not trivial. At high frequencies, the parasitic capacitance of the ADC’s package can become a significant component in the overall input impedance. Take a look at Figure 2, the equivalent input circuit of an example ADC with a wide input bandwidth. The measured –3dB full power bandwidth (FPBW) of the ADC is ~2.3GHz (the frequency at which the input signal is attenuated by 3dB before being digitized). Notice that before the input signal gets to the die, it passes through parasitic capacitance and inductance in the package, bond wire, and bond pad. The ADC track-and-hold and sampling capacitor are located passed the buffer inside the ADC. The frequency characteristics of the sampling circuits affect FPBW, but are isolated from affecting the VSWR of the analog inputs because of the presence of the buffer. This is important to point out, as it is not sufficient to use the ADC’s FPBW specification as a final answer to the question of whether or not the ADC can be driven at the frequency of interest.Challenges of Clock JitterOne requirement that is not eliminated by removing a mixing stage is the high-quality oscillator. Instead of driving a mixer with an oscillator, you drive the ADC clock input. The ADC is essentially providing the mixing by means of the clock and sampling circuit. The higher the analog input frequency, the tighter the requirement for total combined jitter between the clock and ADC. To give you an order of magnitude: if an ADC has internal aperture jitter of ~150fs, the RMS jitter at the ADC clock input pins must be <50fs to achieve 60dBc signal-to-noise ratio (SNR) at 1200MHz analog input frequency. The clock jitter requirement is a function of the analog input frequency, not the clock frequency. A high-quality oscillator and likely a bandpass filter are required in the clock path to achieve such low RMS jitter. A discussion on how to determine the required jitter is detailed in “High-IF sampling A/D converters beyond baseband frequencies,” written by Chuck Sanna [1] as well as the ADS54RF63 datasheet [2]. Distortion, Noise, and EVMENOB is a function of both noise and distortion and is an excellent way to summarize the overall quality of a converter. Sometimes one or the other is dominant in the ENOB calculation. Depending on the bandwidth of the signal of interest, some systems can achieve the desired ADC noise floor through the processing gain of decimation. Distortion can lead to noise in the data link, so it is important to look at the achievable spurious-free dynamic range (SFDR) at the frequency of interest. The SFDR is a measure of the worst spur, usually a distortion component and cannot be easily improved without adding the complexity of dithering circuits or digital linearization techniques, which are limited in effectiveness. A wideband modulated signal will also modulate onto the ADC’s distortion. Often this will fall across the signal of interest in the frequency domain (due to aliasing), adding to the in-band noise. If the distortion is good, the modulated version of it will be low in magnitude and cause added in-band noise. If the ADC is receiving a wideband modulated signal and the distortion is not adequate, the error vector magnitude (EVM) will be degraded and the constellation points harder to detect, ultimately leading to a higher bit error rate for the data link. As technology and design know-how continue to improve, the performance at high IF and clock rates should continue to increase. 2. To download datasheets, order samples or evaluation modules, visit:www.ti.com/ads5474[3]. About the Author Philip M. Pratt is a Systems Engineer for High-Speed ADCs at Texas Instruments. Philip received a BSEE from the University of Tennessee, Knoxville and a MSEE from Florida Institute of Technology, Melbourne. Previously analog-to-digital converters (ADC) at high input frequencies were limited in usefulness due to distortion and noise performance. Today, however, ADCs can provide nearly 9.5 bits of effective number of bits (ENOB) at radio frequencies (RF) of 1 GHz with signal bandwidths greater than 200MHz. Such performance at high frequencies eliminates a mixer stage, simplifying receiver design to improve overall system performance. | High | [
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1. Introduction {#sec1} =============== Natural enzymes have high catalytic efficiency and excellent specificity.^[@ref1]^ These properties lead to their wide application in detection,^[@ref2]^ drug delivery,^[@ref3]^ and the degradation of organic pollutants.^[@ref4]^ As for the detection, natural horseradish peroxidase (HRP) has been used in the catalytic oxidation of colorless 3,3,5,5-tetramethylbenzidine (TMB) into blue oxidized TMB (oxTMB) in the bio-related detection, and oxTMB has a high molar absorption coefficient.^[@ref5]^ However, natural enzymes are relatively expensive and easy to be inactivated by the surrounding environment. It is important to seek mimic enzymes to overcome the shortage and maintain the merit of natural enzymes. Gao and co-workers first reported that magnetic Fe~3~O~4~ nanoparticles (NPs) possessed peroxidase-like activity.^[@ref6]^ Besides, many other nanomaterials have been demonstrated to exhibit good peroxidase-like properties, such as Co~3~O~4~,^[@ref7]^ Co~4~N nanowires,^[@ref8]^ Prussian blue,^[@ref9]^ graphene oxide,^[@ref10]^ and noble metal nanoparticle.^[@ref11]^ These nanomaterials have more flexible structures and higher chemical stability compared with HRP. They are capable of catalyzing the oxidation of TMB into blue oxTMB, which have been further used to detect glucose concentration. For example, core--shell gold nanorods were used for the colorimetric determination of glucose in the range of 2.5--200 μM;^[@ref12]^ TiO~2~-encapsulated Au (Au\@TiO~2~) yolk--shell had a linear range in 5--100 μM and a detection limit of 4.0 μM.^[@ref13]^ However, many nanomaterials lack high stability in solution, which restrains their catalytic efficiency. Platinum element is widely used in chemical industries. Several platinum NPs (Pt NPs) possess mimetic activities.^[@ref14]−[@ref17]^ The improvement of the catalytic activity of Pt NPs still has received increasing attention.^[@ref18]−[@ref20]^ Smaller NPs often have larger specific surface areas. However, they are likely to form aggregation in aqueous solution because of their larger surface energy, which would restrict their catalytic efficiency. In fact, the catalytic efficiency of Pt NPs is dependent on the number of available active sites on the surface of NPs. Stable Pt NPs in aqueous solution tend to have more accessible active sites. Thus, many substances have been employed to stabilize the metal NPs, and a substantial fraction of the surface of the metal NPs participates in catalytic reactions.^[@ref21],[@ref22]^ These substances include bovine serum albumin,^[@ref23]^ yeast extract,^[@ref24]^ sodium polyacrylate,^[@ref25]^ polyvinylpyrrolidone (PVP),^[@ref26]^ and dendrimers.^[@ref27]^ Platinum NPs using bovine serum albumin have salt-resistant property.^[@ref23]^ Small Pt nanoclusters were prepared using yeast extract as the reductant and stabilizer.^[@ref24]^ Sodium polyacrylate-stabilized Pt NPs had 3.25 times higher hydrogen generation activity than that of Pt NPs without stabilization under the same conditions.^[@ref25]^ Pt nanocubes were capped by PVP,^[@ref28]^ and Pt NPs were prepared using dendrimers terminated with alkyl chains as the template.^[@ref29]^ However, polyvinylpyrrolidone may cause cancers, and dendrimers are too expensive to be scaled up. In contrast, polyethyleneimine (PEI) has an affordable price and the highest cationic density among water-soluble polymers, providing its potential to stabilize metal NPs in large scale. In addition, the linear PEI molecule should keep most of the catalytic center of Pt NPs available. The higher amount of catalytic center could lead to the higher catalytic oxidation of TMB and obvious change. Pt NPs (12.9--70.7 nm) have been successfully prepared by PEI molecules with molecular weights from 300, 1200, and 10,000.^[@ref30]^ However, the sizes of aforementioned Pt NPs are relatively big, and the stability of prepared NPs is not investigated. Thus, it is still necessary to obtain smaller Pt NPs with high stability in solution. In this work, a facile method to prepare PEI (*M*~w~ 70,000)-stabilized platinum NPs (Pt~*n*~-PEI NPs) was developed. The monodispersed Pt~*n*~-PEI NPs were highly stable. Pt~*n*~-PEI NPs efficiently catalyzed TMB with H~2~O~2~ to produce blue oxTMB. More importantly, the blue color of this system was dependent on the concentration of glucose. Thus, a colorimetric method based on Pt~*n*~-PEI NPs to sensitively detect glucose concentration was established for the first time. The glucose concentration of saliva was measured, suggesting the great potential of Pt~*n*~-PEI NPs for bio-related detection. 2. Results and Discussion {#sec2} ========================= 2.1. Characterization of Pt~*n*~-PEI NPs {#sec2.1} ---------------------------------------- The Pt~*n*~-PEI NPs were prepared by mixing PEI solution (pH = 4.0, 1 mg/mL) and K~2~PtCl~4~ (2 mM) aqueous solution in PE tubes, where PEI was used as the template and NaBH~4~ was used as the reducing agent. All the tubes were located in a constant temperature metal mixer at 20 °C for 20 min. PtCl~4~^2--^ and nitrogen atom of the PEI formed a complex. The concentration of PtCl~4~^2--^ around nitrogen atoms of the PEI was much higher than that of bulk solution. Then, PtCl~4~^2--^ was very quickly reduced to zero-valent Pt atoms by the addition of strong reducing agent NaBH~4~. These Pt atoms gathered together to Pt NPs which stabilized by PEI. This reduction process was monitored by UV--vis spectra. [Figure [1](#fig1){ref-type="fig"}](#fig1){ref-type="fig"}a showed that the K~2~PtCl~4~ had an obvious characteristic absorption peak at 320 and 383 nm corresponding to d--d transitions.^[@ref31]^ Two peaks were weakened after incubation of K~2~PtCl~4~ with PEI. After the addition of NaBH~4~, a broad and continuous absorption appeared. In addition, as shown in [Figure [1](#fig1){ref-type="fig"}](#fig1){ref-type="fig"}b, when the molar ratio of K~2~PtCl~4~ to PEI increased from 50 to 150, the absorbance of Pt~*n*~-PEI NPs gradually increased. The Pt~*n*~-PEI NPs were well dissolved in aqueous solution. PAMAM dendrimer-encapsulated Pt NPs also had similar results.^[@ref29]^ Taken together, the results indicated the successful preparation of Pt~*n*~-PEI NPs. {#fig1} As shown in [Figure [2](#fig2){ref-type="fig"}](#fig2){ref-type="fig"}, PEI had several peaks from 2.45 to 2.74 ppm, which were assigned to the proton of −C***[H]{.ul}***~2~--C***[H]{.ul}***~2~-- from the PEI skeleton. After the stabilization of Pt NPs by PEI, the ^1^H NMR spectrum of Pt~50~-PEI had a wider range from 2.45 to 3.28 ppm than that of PEI. The difference should be due to the encapsulation some proton peaks of −C***[H]{.ul}***~2~--C***[H]{.ul}***~2~-- from the PEI skeleton by Pt NPs. {#fig2} The size of metal NPs has a great impact on their catalytic efficiency. As shown in [Figure [3](#fig3){ref-type="fig"}](#fig3){ref-type="fig"}, the sizes of prepared Pt NPs stabilized by PEI were examined by transmission electron microscopy (TEM). The sizes of Pt NPs for Pt~50~-PEI, Pt~100~-PEI, and Pt~150~-PEI were 3.21 ± 0.87, 3.38 ± 0.74, and 3.7 ± 0.75 nm, respectively. It should be noted that as the molar ratio of K~2~PtCl~4~ to PEI increased, the sizes of Pt NPs increased. Thus, Pt NPs had very small sizes with a narrow size distribution. They also had high dispersity without aggregation and high specific surface areas. However, the Pt NPs without stabilization by PEI showed obvious aggregation and big size ([Figure S1](http://pubs.acs.org/doi/suppl/10.1021/acsomega.0c00147/suppl_file/ao0c00147_si_001.pdf)). Thus, PEI with proper molecular weight was important for the high stability and size control of Pt NPs. One of the most common methods selected to synthesize Pt NPs involves the use of sodium polyacrylate^[@ref25]^ and polyvinylpyrrolidone.^[@ref26]^ The size of Pt NPs with sodium polyacrylate was about 50 nm with certain aggregation.^[@ref25]^ PVP is a nonionic polymer, while PEI is a cationic polymer. Spherical Pt NPs are prepared within the size from 16 to 23 nm using *Punica garanatum* peel extract.^[@ref32]^ The Pt NPs (10--50 nm) are synthesized using Prunus × yedoensis tree gum.^[@ref33]^ In short, a facile method of preparation of Pt~*n*~-PEI was established, where PEI (70,000) was used to control the size of Pt NPs and enhance the stability of Pt~*n*~-PEI. {#fig3} X-ray photoelectron spectroscopy (XPS) is commonly used to study the surface element composition and valence state of metal composite materials.^[@ref34]^ Herein, as shown in [Figure [4](#fig4){ref-type="fig"}](#fig4){ref-type="fig"}a, the peaks at 284.6 and 398.9 eV were assigned to C 1s and N 1s, respectively. They were from PEI. The peak at 529.3 eV was attributed to O 1s indicating the presence of H~2~O, which was because of the strong binding water ability of PEI. [Figure [4](#fig4){ref-type="fig"}](#fig4){ref-type="fig"}b further showed that the binding energy of the Pt 4f had two characteristic peaks at 72.6 and 75.8 eV, which belonged to the Pt 4f~7/2~ and Pt 4f~5/2~ orbits, respectively. Pt NPs with zero valence prepared by Natarajan Prabu had 72.21 and 75.81 eV. Thus, Pt(II) has been reduced by NaBH~4~ to generate Pt (0). The slight difference should be due to the different size of Pt NPs and surface properties.^[@ref35]^ In short, XPS results demonstrated the successful preparation of Pt (0) stabilized by PEI. {#fig4} Furthermore, the hydration status and stability of Pt~50~-PEI NPs were measured using DLS technology. The changes of the hydrodynamic size of Pt~50~-PEI NPs under different pH from 4 to 9 were used to evaluate their stability. As shown in [Figure [5](#fig5){ref-type="fig"}](#fig5){ref-type="fig"}a, the hydrodynamic size of Pt~50~-PEI NPs was about 25 nm within one week, indicating their high stability for a long time. In contrast, the Pt NPs without the stabilization of PEI gradually precipitated. The hydrodynamic size of Pt~50~-PEI NPs included the PEI molecule, which was bigger than the size of Pt NPs measured by using TEM. Furthermore, [Figure [5](#fig5){ref-type="fig"}](#fig5){ref-type="fig"}b showed that the zeta potential of Pt~50~-PEI NPs changed from 9.4 ± 2.7 mV at pH 1 to 4.9 ± 2.6 mV at pH 10. The stability of NPs was dependent on the zeta potential and polymer template. High zeta potential of NPs (\>30 mV) means their good stability.^[@ref36],[@ref37]^ In addition, the polymer template inhibits agglomeration of NPs by steric effects.^[@ref38],[@ref39]^ As for Pt~50~-PEI NPs, electrostatic repulsion and steric hindrance between Pt~50~-PEI NP result in their high stability which was beneficial to catalytic oxidation of TMB for a long time.^[@ref40]^ In short, Pt~50~-PEI NPs had high stability with a hydrodynamic size of ∼25 nm and slightly positive charge. {#fig5} 2.2. Peroxidase-like Activity Assays {#sec2.2} ------------------------------------ Many substrates such as TMB and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) can be effectively catalyzed by HRP. Herein, TMB was catalyzed by Pt~50~-PEI NPs in the presence of H~2~O~2~ at pH 4. [Figure [6](#fig6){ref-type="fig"}](#fig6){ref-type="fig"} showed that Pt~50~-PEI catalyzed the oxidation of TMB with H~2~O~2~ to generate a characteristic absorption peak at 652 nm (*A* = 0.488) which corresponded to blue oxTMB solution.^[@ref41]^ However, other groups were still colorless and the absorbance (*A* = 0.046) was lower than 0.488, indicating the absence of oxTMB. These results demonstrated that the Pt~50~-PEI NPs catalyzed the oxidation of TMB in the presence of H~2~O~2~, indicating their peroxidase-like activity. In addition, the bottom of the bottle was clear, suggesting the high stability of Pt~50~-PEI NPs in the catalytic process. Stable Pt~50~-PEI NPs in aqueous solution tend to have more available active sites. TMB molecules and H~2~O~2~ molecules were absorbed on the active sites of Pt NPs. The free electron was transferred from TMB to H~2~O~2~ on the active sites of Pt NPs. Platinum NPs decorated on nickel- and nitrogen-doped graphene nanotubes also have peroxidase-like activity; the corresponding groups have obvious absorbance at 652 nm.^[@ref42]^ In short, Pt~50~-PEI NPs had significant peroxidase-like activity. ![(a) Spectra of different solutions: \[TMB + H~2~O~2~\], \[TMB + Pt~50~-PEI\], \[H~2~O~2~ + Pt~50~-PEI\], and \[TMB + Pt~50~-PEI + H~2~O~2~\] and (b) corresponding solution. Pt~50~-PEI NPs had peroxidase-like activity.](ao0c00147_0006){#fig6} 2.3. Catalytic Activity {#sec2.3} ----------------------- Generally, the catalytic activity of natural enzymes is dependent on their structure and conformation, which were influenced by the surrounding conditions (pH and temperature). Herein, the effects of pH values (from 2 to 12) and the temperature (from 10 to 60 °C) on the catalytic activities of Pt~50~-PEI were carefully investigated, respectively. As shown in [Figure [7](#fig7){ref-type="fig"}](#fig7){ref-type="fig"}a, the maximum relative activity of Pt~50~-PEI was pH 4.0. Thus, pH 4.0 was optimal pH values for the TMB oxidation reaction, which was similar to those of other NPs.^[@ref43],[@ref44]^ In addition, as shown in [Figure [7](#fig7){ref-type="fig"}](#fig7){ref-type="fig"}b, when the temperature was from 10 to 60 °C, the catalytic reaction reached the highest relative activity at 30 °C. In short, pH 4.0 and temperature 30 °C were the optimal conditions and were chosen for subsequent experiments.^[@ref45]−[@ref47]^ {#fig7} 2.4. Kinetic and Mechanism Study {#sec2.4} -------------------------------- Furthermore, the peroxidase-like catalytic performance of Pt~50~-PEI with H~2~O~2~ or TMB as substrates was measured using the steady-state kinetics. The enzymatic kinetic parameters were measured under conditions with altering concentrations of H~2~O~2~ or TMB while fixing the other one invariable. The initial reaction rate was calculated on the basis of the production of oxTMB over time. The molar absorption coefficient of oxTMB was 39,000 M^--1^·cm^--1^. As shown in [Figure [8](#fig8){ref-type="fig"}](#fig8){ref-type="fig"}a and [Figure [8](#fig8){ref-type="fig"}](#fig8){ref-type="fig"}b, the initial reaction rate (*v*) of Pt~50~-PEI was dependent on the substrate (TMB or H~2~O~2~) concentration. Both curves confirmed that the catalytic reaction of Pt~50~-PEI followed a typical Michaelis--Menten equation. MoS~2~--Pt~74~Ag~26~, Fe-doped CeO~2~ nanorods, and PVP-functionalized ultra-small MoS~2~ NPs also exhibit typical Michaelis--Menten kinetics.^[@ref48]−[@ref50]^ As shown in [Figure [8](#fig8){ref-type="fig"}](#fig8){ref-type="fig"}c,d, the 1/*v* was proportional to 1/H~2~O~2~ concentration and 1/TMB concentration, respectively. The Michaelis constant (*V*~max~ and *K*~m~) was shown in [Table [1](#tbl1){ref-type="other"}](#tbl1){ref-type="other"}. The *V*~max~ values toward TMB of Pt~50~-PEI NPs were much bigger than that of HRP, indicating that Pt~50~-PEI NPs had higher catalytic activity than HRP. The high catalytic activity should be due to free access to the active sites of NPs for the substrates. Water-soluble PEI enhanced the stability of small Pt NPs, while PEI should not occupy the active sites of Pt NPs. It has been reported that PVP was strongly adsorbed onto the surface of NPs, and surface-adsorbed PVP blocked reactant molecules to access the active sites of NPs.^[@ref51]^ Chen and co-worker found that the peroxidase-like activity of graphene oxide--Fe~3~O~4~ magnetic nanocomposites follows a ping-pong mechanism.^[@ref52]^ The peroxidase-like activity of Pt~50~-PEI NPs should also follow a ping-pong mechanism. In short, Pt~50~-PEI NPs had typical Michaelis--Menten equation for the catalytic oxidation of TMB. {#fig8} ###### Kinetic Parameters of Pt~50~-PEI NPs and HRP catalyst substrate *K*~m~ (mM) *V*~max~ (10^--8^ Ms^--1^) reference ------------ ----------- ------------- ---------------------------- ------------ Pt~50~-PEI TMB 2.02 115 this work Pt~50~-PEI H~2~O~2~ 43.6 8.50 this work HRP TMB 0.434 10.00 ([@ref6]) HRP H~2~O~2~ 3.70 8.71 ([@ref6]) PtNPs/GO TMB 0.1864 10.20 ([@ref53]) PtNPs/GO H~2~O~2~ 221.4 12.45 ([@ref53]) 2.5. Glucose Detection {#sec2.5} ---------------------- The Pt~50~-PEI-catalyzed TMB to generate blue oxTMB which had an obvious absorbance peak at 652 nm in the UV--vis spectra. Thus, the concentration of oxTMB can be calculated based on its absorbance at 652 nm. The concentration of oxTMB was proportional to H~2~O~2~ concentration. It has been reported that the H~2~O~2~ concentration was dependent on the glucose concentration in the glucose oxidase (GOD)-catalyzed reaction in the presence of glucose and oxygen. Thus, combining two catalytic reactions using Pt~50~-PEI and GOD, the concentration of oxTMB should be dependent on the glucose concentration. [Figure [9](#fig9){ref-type="fig"}](#fig9){ref-type="fig"}a showed that the absorbance of oxTMB at 652 nm was positively correlated with the glucose concentration which was from 10--5000 μM. The standard response equation of glucose concentration was *A* = 0.0485C~glucose~ + 0.191. The detection limit was 4.2 μM, which was relatively small when it was compared with other reported NPs ([Table [2](#tbl2){ref-type="other"}](#tbl2){ref-type="other"}). Cysteine-modified MoS~2~ nanoflakes (Cys--MoS~2~ NFs) were used for the colorimetric detection of glucose with a detection limit for 33.51 μM and the linear range from 0.05--1 mM.^[@ref54]^ The high stability of Pt~50~-PEI NPs was good for the quick color change of TMB. Saliva was used as the real sample to test the glucose concentration. The glucose concentration was 0.15 mM, which was within a normal glucose concentration of human saliva (0.008--0.21 mM).^[@ref55]^ This confirmed the validity of this method. Thus, a sensitive colorimetric method for glucose detection was established based on the peroxidase-like activity of Pt~50~-PEI NPs. {#fig9} ###### Linear Range and Detection Limit of Mimetic Enzyme mimetic enzyme linear range (μM) detection limit (μM) method reference ------------------------------------ ------------------- ---------------------- ------------------ ------------ Pt~50~-PEI 10--5000 4.2 colorimetry yhis work Pt~200~-JP NCs 10--1000 5.47 colorimetry ([@ref57]) Pt NPs 1--50 1 colorimetry ([@ref58]) GNRs-CQDs 10--2000 3.0 colorimetry ([@ref59]) NiFe-LDHNS 50--2000 23 colorimetry ([@ref60]) MoS~2~ NPs 15--135 7 colorimetry ([@ref61]) Por-ZnFe~2~O~4~ HSs 6--90 5.5 colorimetry ([@ref62]) Ag\@Fabric 100--2000 80 colorimetry ([@ref63]) Cys-MoS~2~ NFs 50--1000 33.51 colorimetry ([@ref54]) PtPd/PHNG-2 100--4000 1.82 electrochemistry ([@ref64]) Pt--Pd nanoflakes 0--16,000 20.6 electrochemistry ([@ref65]) Pt--Pb bimetallic nanostructure/Au 0--12,000 8.4 electrochemistry ([@ref66]) Furthermore, selectivity of glucose detection was evaluated by using maltose, fructose, and lactose as control groups. The concentrations of glucose and other sugars were 5 and 10 mM, respectively. As shown in [Figure [9](#fig9){ref-type="fig"}](#fig9){ref-type="fig"}b, the absorbance of control groups was much lower than that of glucose when the concentration of glucose was half of that of other sugars. Thus, this detection method had high selectivity toward glucose, which was because of the specificity of GOD toward the catalytic oxidation of β-*d*-glucose to gluconic acid using molecular oxygen.^[@ref56]^ In addition, the developed method showed acceptable reproducibility. In short, a selective method using Pt~*n*~-PEI NPs was demonstrated. Compared with the electrochemical method, a colorimetric method using Pt~*n*~-PEI NPs has many merits such as convenience, low cost, simplicity, and practicality. 3. Conclusions {#sec3} ============== In summary, PEI (70,000) was used as a template to construct water-soluble, stable, and monodispersed Pt~*n*~-PEI NPs. Based on the peroxidase-like activity of Pt~50~-PEI NPs, a highly sensitive method for the detection of glucose concentration was established. The size of Pt NPs inside Pt~*n*~-PEI NPs ranged from 3.21 to 3.70 nm. Pt~50~-PEI NPs had a hydrodynamic size of ∼25 nm and slightly positive charge. Furthermore, Pt~50~-PEI NPs showed peroxidase-like reaction, which was used to detect the glucose concentration. This detective method had a linear glucose concentration range from 10 to 5000 μM, low detection limit, and high selectivity. The concentration of glucose in saliva was tested to be 0.15 mM. The suitable molecular-weight PEI was used to keep high stability of Pt NPs (3.21 nm) inside of Pt~50~-PEI NPs in solution. Pt~50~-PEI NPs could be prepared in large scale because of affordable price. This high stability of Pt~50~-PEI NPs was beneficial to the sensitive detection of glucose concentration in the solution system. Our future work will focus on the relationship between surface groups of soluble macromolecules and the catalytic ability of metal NPs. This established method has great potential to be used for glucose detection in the future. 4. Methods {#sec4} ========== 4.1. Synthesis of Pt~*n*~-PEI NPs {#sec4.1} --------------------------------- The synthesis of Pt~*n*~-PEI NPs was as follows: as for Pt~50~-PEI NPs, 357 μL of K~2~PtCl~4~ (2 mM) aqueous solution and 1000 μL of PEI solution (pH = 4.0, 1 mg/mL) were mixed and added in a PE tube. As for Pt~100~-PEI NPs, 357 μL of K~2~PtCl~4~ (2 mM) aqueous solution and 500 μL of PEI solution (pH = 4.0, 1 mg/mL) were mixed and added in a PE tube. As for Pt~150~-PEI NPs, 535.5 μL of K~2~PtCl~4~ (2 mM) aqueous solution and 500 μL of PEI solution (pH = 4.0, 1 mg/mL) were mixed and added in a PE tube. The molar ratio of K~2~PtCl~4~ to PEI was 50:1, 100:1, and 150:1, respectively. All the tubes were located in a constant temperature metal mixer at 20 °C for 20 min. Then, NaBH~4~ (1 mg/mL) solution was dissolved in 0.3 M NaOH and added into each tube. The amount of NaBH~4~ was 135 μL for Pt~50~-PEI NPs, 135 μL for Pt~100~-PEI NPs, and 203 μL for Pt~150~-PEI NPs. After 10 min, the solution was tuned to a pH of 7 with 1 M HCl. The solution was shaken at 500 rpm for another 3 h. Each group solution was collected and dialyzed against ultrapure water to obtain Pt~*n*~-PEI NPs (*n* = 50, 100, 150). 4.2. Catalytic Activity {#sec4.2} ----------------------- The catalytic activity of Pt~50~-PEI NPs under different pH (2.0--12.0) was evaluated as follows: 200 μL of Pt~50~-PEI (6 μM) and 800 μL of HAc-NaAc buffer (pH 2.0--12.0, 0.2 M) were incubated for 10 min; 200 μL of TMB (0.6 mM) was mixed for 10 min; Then, 200 μL of H~2~O~2~ (0.3 M) was added for 10 min. The absorbance was recorded at 652 nm. The catalytic activity of Pt~50~-PEI NPs under different temperatures (10--60 °C) was carried out with the same procedure at pH 4.0. 4.3. Michaelis--Menten Kinetic Analysis {#sec4.3} --------------------------------------- The effect of the H~2~O~2~ concentration (0.039--0.177 mM) and TMB concentration (0.018--0.357 mM) on the catalytic activity of Pt~50~-PEI was studied at 30 °C, respectively. Briefly, the kinetic assays of Pt~50~-PEI with H~2~O~2~ as the substrate were performed by adding 25 μL of Pt~50~-PEI (2 μM), 1400 μL of TMB (0.8 mM), and different amounts of H~2~O~2~ (3 M). The kinetic assays of Pt~50~-PEI with TMB as the substrate were performed by adding 100 μL of Pt~50~-PEI (6 μM), 300 μL of H~2~O~2~ (0.3 M), and different amounts of TMB solution (0.2 M HAc-NaAc, pH 4.0). Catalytic parameters were determined based on Michaelis--Menten [eq [1](#eq1){ref-type="disp-formula"}](#eq1){ref-type="disp-formula"}. 4.4. Glucose Detection {#sec4.4} ---------------------- \(a\) GOD (100 μL, 5 mg/mL) and glucose (200 μL) solutions with different concentrations were incubated at 37 °C for 30 min, the glucose was dissolved in HAc-NaAc buffer (pH = 5.2, 0.2 M); (b) 800 μL of TMB (0.6 mM) and 100 μL of the Pt~50~-PEI solution (6 μM) were mixed at 30 °C for 5 min. This (b) solution was added into 300 μL of (a) solution, the mixed solution was incubated at 30 °C for 30 min, and the absorbance was recorded at 652 nm. Glucose (5 mM) and other sugars (10 mM) were also measured to compare the selectivity of this method. The glucose concentration of saliva was measured using our method. The Supporting Information is available free of charge at [https://pubs.acs.org/doi/10.1021/acsomega.0c00147](https://pubs.acs.org/doi/10.1021/acsomega.0c00147?goto=supporting-info).Materials, characterization, peroxidase-like activity assays, and TEM images of Pt NPs without PEI ([PDF](http://pubs.acs.org/doi/suppl/10.1021/acsomega.0c00147/suppl_file/ao0c00147_si_001.pdf)) Supplementary Material ====================== ###### ao0c00147_si_001.pdf The manuscript was written through contributions of all the authors. All the authors have given approval to the final version of the manuscript. The authors declare no competing financial interest. The authors appreciate financial support Natural Science Foundation of Hebei Province (B2017203229) and China Postdoctoral Science Foundation (2016M601284). | Mid | [
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Japan’s new cabinet line-up to promote remilitarisation By Peter Symonds 6 August 2016 In the wake of the ruling Liberal Democratic Party’s (LDP) gains in last month’s upper house election, Japanese Prime Minister Shinzo Abe reshuffled his cabinet on Wednesday in a move that presages further steps towards remilitarisation and pro-market restructuring. The most significant promotion was that of Tomomi Inada to the post of defence minister. Inada, a protégé of Abe, is well known for her extreme right-wing nationalist views. Although in parliament for just 11 years, she has already been mentioned as a possible future prime minister. Inada, a lawyer by training, is an outspoken advocate of revising the country’s constitution to remove or modify Article 9, which renounces war and affirms that land, sea or air forces will never be maintained. Successive governments have already eviscerated Article 9 by allowing for the establishment and expansion of the military as “self defence forces.” Last year, the Abe government took a further major step by enacting legislation allowing for “collective self defence”—that is, for Japan to more directly participate in US-led wars. Abe, however, is keen to press ahead with a full-blown constitutional revision, having obtained the necessary two-thirds majority in the upper and lower houses of parliament. The LDP has long sought to not only revise Article 9, but also restore the emperor to his pre-war role as linchpin of the state apparatus and make inroads into democratic rights presently guaranteed in the constitution. In pressing ahead with this agenda, Inada is a key political ally. She is a member of Nippon Kaigi or Japan Conference, the parliamentary group that promotes the lie that Japan went to war in the 1930s to liberate Asia from Western imperialism. It calls for the revision of school textbooks to promote “patriotic values” and remove all references to war crimes such as the Rape of Nanking. In 2014, a photo surfaced in the media taken in 2011 of a smiling Inada alongside Kazunari Yamada, leader of the fascist National Socialist Japanese Labor Party and open admirer of Adolf Hitler. Inada claimed that she did not know who Yamada was or the politics he expoused. Inada has a long history of defending the crimes of the Japanese military during the 1930s and 1940s. She has supported figures such as Takashi Kawamura, who, as Nagoya mayor, suggested that the 1937 Nanking massacre, in which the Japanese army murdered up to 300,000 captured Chinese soldiers and civilians, did not happen. She is also a visitor to the Yasukuni Shrine to the country’s war dead, a notorious symbol of Japanese militarism. As the newly appointed defence minister, Inada will play a prominent role in the expansion of the Japanese armed forces and their integration into the US “pivot to Asia” and its preparations for war against China. Her denial of past war crimes and support for constitutional revision are in line with Japanese imperialism more aggressively prosecuting its economic and strategic interests, including by force. Inada is the second woman to become defence minister. Yuriko Koike quit her post in June to run for the powerful position of Tokyo governor, which she won last month after defeating the LDP’s endorsed candidate. Koike is a prominent member of Nippon Kaigi, visitor to the Yasukuni Shrine and supporter of constitutional change. Senior LDP figures, including Abe, maintained neutrality during the election campaign, thus tacitly supporting Koike. The other new ministers in the Abe cabinet were selected with the aim of reinforcing so-called "Abenomics," which has faced criticism as the Japanese economy has continued to stagnate. A survey of economists by the Japan Centre for Economic Research suggested that annualised growth has slumped to just 0.1 percent in the second quarter, down from 1.9 percent in the first quarter. Abe installed one of his close economic advisers, Kozo Yamamoto, as minister in charge of regional revitalisation. Yamamoto has been an outspoken advocate of Japan’s version of quantitative easing—that is, pumping huge amounts of ultra-cheap credit into the financial system. In a 2015 interview, he declared that he was worried that Bank of Japan (BoJ) Governor Haruhiko Kuroda might be facing a “den of conspirators” opposed to his policies of monetary stimulus. Yuji Shimanaka, chief economist at Mitsubishi UFJ Morgan Stanley, told Bloomberg.com: “Yamamoto is a mastermind of Abenomics and coming into the cabinet makes him a closer adviser. Monetary policy and the BoJ are his lifework and his beliefs won’t waver at all.” However, Japan’s version of quantitative easing has been no more successful than in other countries in reviving productive activity. Rather, it encouraged speculative activities that have benefited a thin layer of the upper-middle class and wealthy at the expense of the majority of the population, which confront worsening job opportunities and declining living standards. On Tuesday, the Abe government announced another huge stimulus package that included 7.5 trillion yen ($US73 billion) in new spending in a desperate effort to revive the economy. While making cash handouts of 15,000 yen, or about $147, to 22 million low-income people, the main thrust of the package is to provide assistance to business via new infrastructure projects. In an extraordinary parliamentary session beginning in September, the government is seeking to pass a second supplementary budget and also to ratify the Trans-Pacific Partnership (TPP), a far-reaching US-led economic pact aimed at shoring up American domination in Asia and undermining China. Yamamoto is also in charge of pushing through the necessary legislative changes to implement the TPP, which will impact heavily on highly-protected sectors of the Japanese economy such as agriculture. The LDP has relied heavily on its base of support in rural areas, which have had strong electoral weight as a result of a gerrymander against urban electorates. Another Abe adviser, Hisoshige Seko, will also promote the TPP as the newly-installed minister for economy, trade and industry. Abe, however, is determined to exploit the TPP as the means of ramming through major pro-market structural changes that will hit not only farmers and other small businesses, but sections of the working class. Successive governments over the past two decades have already substantially dismantled the post-war life-long employment system, with 38 percent of the workforce now in low-paid casual and part-time jobs. | Low | [
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import React from 'react'; import styled from 'styled-components'; import { Link } from 'react-router-dom'; import palette from '../../lib/styles/palette'; import Button from '../common/Button'; /** * 회원가입 또는 로그인 폼을 보여줍니다. */ const AuthFormBlock = styled.div` h3 { margin: 0; color: ${palette.gray[8]}; margin-bottom: 1rem; } `; /** * 스타일링된 input */ const StyledInput = styled.input` font-size: 1rem; border: none; border-bottom: 1px solid ${palette.gray[5]}; padding-bottom: 0.5rem; outline: none; width: 100%; &:focus { color: $oc-teal-7; border-bottom: 1px solid ${palette.gray[7]}; } & + & { margin-top: 1rem; } `; /** * 폼 하단에 로그인 혹은 회원가입 링크를 보여줌 */ const Footer = styled.div` margin-top: 2rem; text-align: right; a { color: ${palette.gray[6]}; text-decoration: underline; &:hover { color: ${palette.gray[9]}; } } `; const ButtonWithMarginTop = styled(Button)` margin-top: 1rem; `; const textMap = { login: '로그인', register: '회원가입' }; /** * 에러를 보여줍니다 */ const ErrorMessage = styled.div` color: red; text-align: center; font-size: 0.875rem; margin-top: 1rem; `; const AuthForm = ({ type, form, onChange, onSubmit, error }) => { const text = textMap[type]; return ( <AuthFormBlock> <h3>{text}</h3> <form onSubmit={onSubmit}> <StyledInput autoComplete="username" name="username" placeholder="아이디" onChange={onChange} value={form.username} /> <StyledInput autoComplete="new-password" name="password" placeholder="비밀번호" type="password" onChange={onChange} value={form.password} /> {type === 'register' && ( <StyledInput autoComplete="new-password" name="passwordConfirm" placeholder="비밀번호 확인" type="password" onChange={onChange} value={form.passwordConfirm} /> )} {error && <ErrorMessage>{error}</ErrorMessage>} <ButtonWithMarginTop cyan fullWidth style={{ marginTop: '1rem' }}> {text} </ButtonWithMarginTop> </form> <Footer> {type === 'login' ? ( <Link to="/register">회원가입</Link> ) : ( <Link to="/login">로그인</Link> )} </Footer> </AuthFormBlock> ); }; export default AuthForm; | Low | [
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Categories Pages UK Parliament is suspended amid scenes of chaos Opposition members of the House of Commons were furious at the five-week prorogation of Parliament, which critics say is an attempt by UK Prime Minister Boris Johnson to silence debate on Brexit and allow the country to slide towards a no-deal split from the European Union. The government insists prorogation — or suspension — is constitutional and entirely normal for a new administration. But that has not satisfied members of Parliament who have dealt Johnson six defeats in six days, blocking a no-deal Brexit and then rejecting a government motion for snap elections on Monday night, in what was the final vote of the parliamentary session. The debates had already been raucous, but chaos really set in when Black Rod, a senior official in the upper chamber, the House of Lords, entered the House of Commons to request the presence of MPs for the prorogation ceremony. The arrival of Black Rod — Sarah Clarke, the first woman to hold the post — was met with a wall of noise from lawmakers opposed to prorogation. A group of opposition MPs then advanced towards the Speaker’s chair and a small scuffle broke out. MPs crowded around Speaker John Bercow, who had announced his resignation earlier on Monday, holding signs reading “Silenced.” Bercow then added to the drama with an extraordinary show of dissent, briefly refusing to heed Black Rod’s order to leave the Commons. ‘Flying flamingo’ He proceeded to denounce Johnson’s decision to prorogue Parliament. “This is not a standard or normal prorogation,” he said. “It’s one of the longest for decades and it represents an act of executive fiat.” Bercow eventually rose from his seat, and was joined by Conservative MPs as they made the walk to the House of Lords. They were followed by chants of “Shame on you.” In the House of Lords, the arcane ceremony got underway. This included the Clerk of the Crown reading out the titles of acts that had been passed in the parliamentary session. As each was announced, the Clerk of the Parliaments turned to face lawmakers and declared “la Reyne le veult” — Norman French for “the Queen wishes it.” In the House of Commons, meanwhile, some lawmakers proceeded to sing songs including the hymn “Jerusalem”, “Scots, wha hae”, ” The Red Flag” and “Bread of Heaven” — in Welsh, and including harmonies. Bercow returned to Commons to confirm the prorogation. It all ended around 2 a.m. (9 p.m. ET) when opposition lawmakers lined up to shake the Speaker’s hand, capping off an acrimonious day in Parliament. Lawmakers will return to Parliament for a Queen’s Speech in mid-October — little more than two weeks before the Brexit deadline is to expire. | Mid | [
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Spread the love When you tell someone that their police department has bayonets, their immediate reaction is denial or ridicule. “Why would cops need bayonets?” they ask. Exactly, why would cops need bayonets? Why do they need grenade launchers, .50 caliber rifles, Apache attack helicopters, camouflage uniforms, or tracked tank-like vehicles for that matter? While there are multiple reasons public servants attempt to justify their need for weapons of war, the fact remains that they do have them and denying it, doesn’t change that fact. Over the past decade, police departments have been using the 1033 program to acquire these weapons of war. The feds provided surplus military hardware to local police to fight a seeming war against its own citizens. These actions went unchecked and very little government, or public oversight existed. Then when the events that took place in Ferguson beamed across the globe, the militarized U.S. police state revealed it’s ugly face to the world. The images of the militarized police in Ferguson made clear that the days of Andy Griffith and Mayberry are a distant memory. They have been replaced by something that looks as if it belongs on a war-torn battlefield in Afghanistan or Iraq. These revelations caused many to question why small police departments across the country were procuring mine-resistant armored personnel carriers, grenade launchers, and other weapons of war. Because of backlash from the citizens, the federal government was forced to act. In January of this year, Obama signed Executive Order 13688. However, this EO appeared to have very little effect on the departments, and largely went ignored, until now. On Thursday, however, police departments across the country were sent a memorandum that sets a deadline for them to return prohibited military equipment. The memo references Recommendation 1.1 to EP 13688 which prohibits the following items in police departments: Tracked Armored Vehicles: Vehicles that provide ballistic protection to their occupants and utilize a tracked system instead of wheels for forward motion. Vehicles that provide ballistic protection to their occupants and utilize a tracked system instead of wheels for forward motion. Weaponized Aircraft, Vessels, and Vehicles of Any Kind: These items will be prohibited from purchase or transfer with weapons installed. These items will be prohibited from purchase or transfer with weapons installed. Firearms of .50‐Caliber or Higher Ammunition of .50‐Caliber or Higher Grenade Launchers: Firearm or firearm accessory designed to launch small explosive projectiles. Firearm or firearm accessory designed to launch small explosive projectiles. Bayonets: Large knives designed to be attached to the muzzle of a rifle/shotgun/long gun for the purposes of hand‐to‐hand combat. Large knives designed to be attached to the muzzle of a rifle/shotgun/long gun for the purposes of hand‐to‐hand combat. Camouflage Uniforms: Does not include woodland or desert patterns or solid color uniforms. The memo states: State and Local LEA’s are directed to return the following equipment to DLA (Defense Logistics Agency) Disposition Services. Tracked Armored Vehicles M-79 Grenade Launchers Bayonets The above items, according to the memo, are to be returned no later than April 1, 2016. Missing from this memo, however, are .50 caliber firearms, camouflage, and weaponized aircraft. The entire process of issuing these weapons only to later recall them speaks to the sheer inefficient manner of the state. As if there would ever be a scenario in which police would need to affix bayonets to protect the public at large; yet departments across the country have acquired thousands of them. While this memo is a start, it does nothing to address the unaccountable and brutal nature of police in America. A police officer does not need a grenade launcher nor a bayonet to violently assault an innocent mother in front of her children. If the federal government were genuinely concerned with addressing the policing problem in the US, they would end the war on drugs. They would stop enforcing victimless crimes altogether. However, it appears that law enforcement is nowhere near ready to give up their ability to throw morally innocent people in cages or extort money from them as this is what justifies their entire existence. Spread the love Sponsored Content: | Mid | [
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<< Previous Game More Zombie Games Next Game >> 10 newly added games ReBird Wheely 8: Aliens Stars from the Sky Lee Lee's Quest 2 Zombies vs Penguins 4 Amigo Pancho: The Death Star Basketball Fury Stacko Level Pack Disaster Will Strike 7 Tiny Diggers Zombies vs Penguins Play as Zombies or Penguins, your call. Whatever you choose, there will be a lot of action in this game. Post a comment Myspace surveys | Mid | [
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We'll be crossing off names from the Washington Redskins roster below as we learn who made the final cut ahead of Saturday's 4 p.m. deadline, at which point all NFL teams must have trimmed their rosters to 53 players. Below the roster, you'll find my own attempt to sort out who will still be with the Redskins come Sunday morning. Crossed out are recent cuts. Confirmed making the team: Via Zac Boyer, Jose Gumbs is in (Dejon Gomes was cut). Pat White made the team too. (you can follow the Redskins beat writers here for breaking news) Note: The four-game suspensions of Jarvis Jenkins and Rob Jackson open up two roster spots that will presumably go back to them once they both return. Quarterback (3): Robert Griffin III and Kirk Cousins are locks to make the squad, and Rex Grossman is a virtual certainty as well. Pat White probably played well enough this preseason to earn a roster spot somewhere, but not on this team. He'll have to continue his NFL comeback in another city. Running back (5): Alfred Morris is locked in as Mike Shanahan's bellcow, Roy Helu Jr. is firmly entrenched as Alf's change-of-pace backup, and Darrel Young is safe as the team's only true fullback. I think the third-most likely of the halfbacks to make the team is actually Chris Thompson, who has way too much upside as a big-play threat to a) give up on and b) risk losing from the practice squad, especially after his 69-yard punt return Thursday night. That being said, I don't think Thompson makes it as the third running back behind Morris and Helu (he'll be the punt returner, though). That distinction, I believe, will go to Evan Royster, who's simply been too steady when called upon in the regular season to cut loose. Keiland Williams made the most of his preseason opportunities, but he gets lost in the numbers crunch. Wide receiver (5): Pierre Garcon, Josh Morgan, Santana Moss, Leonard Hankerson and Aldrick Robinson are all locks. A lot of people are speculating that the Redskins go with six wide receivers, but I don't see it. It's relatively easy to stash receivers on the practice squad that can fill in and give replacement-level value as a 4th-or-5th wideout in the event of injury. Plus, if Chris Cooley could once split out wide in this offense, then Jordan Reed and Niles Paul sure as heck can, too. Dezmon Briscoe is not eligible for the practice squad (and will likely get picked up by another team), but Nick Williams, Lance Lewis and Skye Dawson are. Tight end (4): No drama here. We've known for some time that the Redskins would be keeping four tight ends, and that they'd be Fred Davis, Logan Paulsen, Jordan Reed and Niles Paul, who will double as Young's backup. Emmanuel Ogbuehi never really had a shot. Offensive line (8): The five starters -- Trent Williams, Kory Lichtensteiger, Will Montgomery, Chris Chester and Tyler Polumbus -- are obviously safe, and I think Tom Compton, Adam Gettis and Josh LeRibeus (merely by virtue of his past draft status) are locked in as backups, as well. I think the Redskins will opt to start the season with eight offensive lineman, but find a way via injury or otherwise to open up a spot later on once Maurice Hurt, who can backup both guard and tackle, comes off the PUP list. Xavier Nixon has real potential, so I think the team stashes him on the practice squad, and gives Tony Pashos, Kevin Matthews and Tevita Stevens their walking papers. Defensive line (6): Again, we know starters Barry Cofield and Stephen Bowen are locks. Kedric Golston is safe as the do-it-all backup and temporary stand-in for Jenkins, who will begin the season serving a four-game suspension. I think Chris Baker and Chris Neild have also secured spots as backup nose tackles, and Philip Merling showed enough in the preseason to stick around until Jenkins returns from his suspension. You can go ahead and say goodbye to Dominique Hamilton, Chigbo Anunoby and Ron Brace. Linebackers (8): This group seems pretty settled. Brian Orakpo, Ryan Kerrigan, London Fletcher and Perry Riley are entrenched as the starters, and Darryl Tapp, Brandon Jenkins, Bryan Kehl and Nick Barnett are set as their backups. Jackson will add a ninth member to this group when he returns from a four-game suspension to begin the season. Will Compton, Marvin Burdette and Vic So'oto don't make the cut. Cornerbacks (6): Once again, little intrigue. DeAngelo Hall and Josh Wilson are your starters, although I wouldn't be surprised if David Amerson starts pushing Wilson for the No. 2 corner job in the very near future. Chase Minnifield and E.J. Biggers are locks to make the team as the No. 4 and 5 corners, and together with Amerson give the Redskins a pretty good, young trio of corners for the future. Note: I originally only had the Redskins carrying five corners, but ended up with an extra roster spot when I got to the end. I think that spot will eventually go to Jackson when he returns from suspension, but for now I'll give it to a sixth corner, since I think it's easier to stash receivers on the practice squad as injury replacements (particularly in this offense) than it is with corners. So congratulations Jerome Murphy, you get to stick around a few more weeks (and even longer if another of the corners gets hurt). Safeties (5): Healthy or not, Brandon Meriweather is making this team, as is Bacarri Rambo and the immortal Reed Doughty, despite the wishes of many (asinine) fans who forget that every winning team has about a half-dozen Doughtys on its roster. Aside from that trio, another couple safeties figure to make the roster, if only because the Redskins need to carry that many. Forced to choose from DeJon Gomes, Jordan Pugh and Jose Gumbs, I'll pinch my nose, go with Gomes and Pugh, and wave bye-bye to Gumbs. I also doubt many teams would come knocking at the door for Pugh's services were he to get cut, so he might be a prime candidate for the chopping block should the team need to make room for Hurt down the line. If the Redskins lose a safety to injury, Pugh will most likely be waiting at home for their call. Specialists (3): No mysteries here. Kai Forbath is your kicker, Sav Rocca is the punter, and Nick Sundberg will handle long-snapping duties. | Low | [
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1. Field of the Invention This invention relates to a method and apparatus for controlling velocity and fuel/air ratio in premixed gas fired burners. 2. Description of the Prior Art Premixed gas fired combustion is known to be a superior combustion mode for minimizing pollutant emissions, in particular, nitrogen oxides (NO.sub.x). However, known methods of premixing fuel and combustion air employ mixing far upstream of the burner nozzle, thereby creating a substantial risk of flame flashback, particularly, at low load operations, due to the nozzle velocity which decreases almost proportionally with load reduction. Another known method of premixing fuel and air, known as nozzle mixing, involves mixing fuel and air within the nozzle. However, such methods cannot achieve perfect mixing due to the poor aerodynamic design and fixed cross-sectional area of the mixing channel in the nozzle. In addition, good mixing of the fuel and air at low load operation is not possible. Finally, known nozzle mixing methods do not permit the ratio of fuel and air to be adjusted within the nozzle to meet the requirements for turndown operation. U.S. Pat. No. 1,702,298 teaches a burner for furnaces having a tubular casing with separate air and combustible gas inlets, the end of the burner casing facing the furnace being open, while the rear end of the casing is in enclosed by a cover having a tubular inward projection to which a threaded extension is attached. Disposed at the outlet end of the tubular projection having an opening through which the combustible gas flows is a tubular sliding piston which is moveable within the burner casing to control the flow of air and gas through the open end of the burner. Similarly, U.S. Pat. No. 4,755,136 teaches a burner for gaseous fuels in which two concentric tubular pistons control the introduction of gaseous fuel and air into a mixing chamber, the gaseous fuel being introduced through openings from the center of the inner piston into the mixing chamber and the air being introduced through openings in the surface of the outer piston into the mixing chamber. A moveable insert for controlling the mixture of fuel and air within the nozzle of a burner is taught by U.S. Pat. No. 1,490,008 which discloses a burner for liquid fuel with a centrally inserted regulating piece having a conical end surrounded by an annular mixing chamber. U.S. Pat. No. 1,289,042 teaches a blow torch having a centrally positioned tube provided with a central passage connected to a gaseous fuel supply source, the tube having a plurality of discharge openings. Slidably mounted on the central gaseous fuel supply tube is a cylindrical valve, the movement of which regulates the amount of air flowing from an annular chamber around the centrally positioned tube as well as the amount of gaseous fuel from the centrally positioned tube through the discharge nozzle of the blow torch. Use of a moveable insert or plug in a mixing chamber area for regulating the flow of fluids therethrough is also taught by U.S. Pat. No. 3,721,387 which teaches an ejector having a variable primary nozzle area and mixing chamber area in which the plug in the mixing area varies not only the area of the primary nozzle but also changes the size of the length of the mixing chamber. See also U.S. Pat. Nos. 1,434,238; 1,127,815; 1,667,365; 2,316,881; and 3,190,283, all of which relate to the combustion of oil, as opposed to a gaseous fuel, having means for adjusting the flow of air to control atomization of the oil and the firing rate of the burners. A premixed gaseous fuel fired burner with velocity and fuel/air ratio control is not taught by the known prior art. | High | [
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Q: Path for the transpiler in WebStorm I'm new to scss and trying to set this whole thing up... I've installed ruby and now have the command line for it (I'm on Windows). Also ran the gem install sass command. Now I need to specify a path under program for the transpiler, to get the watcher to work and translate the scss files to css. The guidelines on the JetBrains website say - "Specify a path variable for the folder where the Ruby executable file and the gem.bat file are stored. This lets you launch Ruby and Gem Manager from any folder and ensures that Ruby is successfully launched during transpilation" I don't understand where and what are the Ruby exectuable file and the supposedly gem.bat that I need to input in that field. A: It must be <Ruby installation dir>/bin/scss.bat, like C:\Ruby193\bin\scss.bat | Mid | [
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Q: OpenCV python: solvePnP ValueError: too many values to unpack import numpy as np import cv2 # Focal length, sensor size (mm and px) f = 33.0 # mm pix_width = 4928.0 # sensor size has 4928px in width pix_height = 3624.0 # sensor size has 4928px in width sensor_width = 23.7 # mm sensor_height = 15.7 # mm # set center pixel u0 = int(pix_width / 2.0) v0 = int(pix_height / 2.0) # determine values of camera-matrix mu = pix_width / sensor_width # px/mm alpha_u = f * mu # px mv = pix_height / sensor_height # px/mm alpha_v = f * mv # px # Distortion coefs D = np.array([[0.0, 0.0, 0.0, 0.0]]) # Camera matrix K = np.array([[alpha_u, 0.0, u0], [0.0, alpha_v, v0], [0.0, 0.0, 1.0]]) import numpy as np import cv2 # Focal length, sensor size (mm and px) f = 33.0 # mm pix_width = 4928.0 # sensor size has 4928px in width pix_height = 3624.0 import numpy as np import cv2 # Focal length, sensor size (mm and px) f = 33.0 # mm pix_width = 4928.0 # sensor size has 4928px in width pix_height = 3624.0 # sensor size has 4928px in width sensor_width = 23.7 # mm sensor_height = 15.7 # mm # set center pixel u0 = int(pix_width / 2.0) v0 = int(pix_height / 2.0) # determine values of camera-matrix mu = pix_width / sensor_width # px/mm alpha_u = f * mu # px mv = pix_height / sensor_height # px/mm alpha_v = f * mv # px # Distortion coefs D = np.array([[0.0, 0.0, 0.0, 0.0]]) # Camera matrix K = np.array([[alpha_u, 0.0, u0], [0.0, alpha_v, v0], [0.0, 0.0, 1.0]]) # Set UV (image) and XYZ (real life) UV_cp = np.array([[1300, 2544], # left down [1607, 1000], # left up [3681, 2516], # right down [3320, 983]],np.float32 ) # right up # Z is on 0 plane, so Z=0.0 XYZ_gcp = np.array([[0, 400, 0], [0, 0, 0], [300, 400, 0], [300, 0, 0]],np.float32) rvec, tvec = cv2.solvePnP(XYZ_gcp, UV_cp, K, D) rotM_cam = cv2.Rodrigues(rvec)[0] # sensor size has 4928px in width sensor_width = 23.7 # mm sensor_height = 15.7 # mm # set center pixel u0 = int(pix_width / 2.0) v0 = int(pix_height / 2.0) # determine values of camera-matrix mu = pix_width / sensor_width # px/mm alpha_u = f * mu # px mv = pix_height / sensor_height # px/mm alpha_v = f * mv # px # Distortion coefs D = np.array([[0.0, 0.0, 0.0, 0.0]]) # Camera matrix K = np.array([[alpha_u, 0.0, u0], [0.0, alpha_v, v0], [0.0, 0.0, 1.0]]) # Set UV (image) and XYZ (real life) UV_cp = np.array([[1300, 2544], # left down [1607, 1000], # left up [3681, 2516], # right down [3320, 983]],np.float32 ) # right up # Z is on 0 plane, so Z=0.0 XYZ_gcp = np.array([[0, 400, 0], [0, 0, 0], [300, 400, 0], [300, 0, 0]],np.float32) rvec, tvec = cv2.solvePnP(XYZ_gcp, UV_cp, K, D) rotM_cam = cv2.Rodrigues(rvec)[0] # Set UV (image) and XYZ (real life) UV_cp = np.array([[1300, 2544], # left down [1607, 1000], # left up [3681, 2516], # right down [3rvec, tvec = cv2.solvePnP(XYZ_gcp, UV_cp, K, D) rotM_cam = cv2.Rodrigues(rvec)[0] # Set UV (image) and XYZ (real life) UV_cp = np.array([[1300, 2544], # left down [1607, 1000], # left up [3681, 2516], # right down [3320, 983]],np.float32 ) # right up # Z is on 0 plane, so Z=0.0 XYZ_gcp = np.array([[0, 400,(rvec)[0] 0], [0, 0, 0], [300, 400, 0], [300, 0, 0]],np.float32) rvec, tvec = cv2.solvePnP(XYZ_gcp, UV_cp, K, D) rotM_cam = cv2.Rodrigues(rvec)[0]320, 983]],np.float32 ) # right up # Z is on 0 plane, so Z=0.0 XYZ_gcp = np.array([[0, 400,(rvec)[0] 0], [0, 0, 0], [300, 400, 0], [300, 0, 0]],np.float32) rvec, tvec = cv2.solvePnP(XYZ_gcp, UV_cp, K, D) rotM_cam = cv2.Rodrigues(rvec)[0] I got this code from OpenCV: use solvePnP to determine homography But I am getting error as : File "solv.py", line 50, in <module> rvec, tvec = cv2.solvePnP(XYZ_gcp, UV_cp, K, D) ValueError: too many values to unpack And how will we find world coordinates xyz . Please help me.........!!!!! A: If you get a ValueError: too many values to unpack it means that there is a mismatch between the number of variables on the left hand side and the number of values returned by the right hand side. In your case: rvec, tvec = cv2.solvePnP(XYZ_gcp, UV_cp, K, D) The method cv2.solvePnP() is most probably returning more than two values in its return tuple. To check this quickly, do: print len(cv2.solvePnP(XYZ_gcp, UV_cp, K, D)) or better yet, see the actual return tuple: print cv2.solvePnP(XYZ_gcp, UV_cp, K, D) and make sure you match the left hand side with this. egs. (untested): rtval, rvec, tvec = cv2.solvePnP(XYZ_gcp, UV_cp, K, D) Check this post for more insight ValueError: too many values to unpack (Python 2.7) | Mid | [
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Tag Archives: Manchester Football League Premier Division Manchester Central will be looking to secure their second win in two weeks over Bolton County when they travel to the side’s Radcliffe Road ground on Saturday in the Manchester Football League Premier Division (KO 14:00). Central already claimed a 5-2 victory over their opponents at home in the Gilgryst Cup at the end of October, […] Manchester Central look to extend an eight game unbeaten run in all competitions when they face Beechfield United in the Manchester Football League Premier Division on Saturday (KO 15:00). Opponents Beechfield go into the match at the Salford Sports Village bottom of the Premier Division, with just one win in their opening nine matches, while […] Manchester Central extended their run to seven games unbeaten with an impressive 5-2 win over Heyside in the Manchester Football League Premier Division on Saturday. Heyside initially took the lead in the match before Marcello Ahrin scored a brilliant chipped shot to equalise the scores. Cory Knight scored a deflected effort to give Central the […] Manchester Central are looking to extend their six game unbeaten run in the Manchester Football League Premier Division when they face Heyside at The Manchester College on Saturday (KO 15:00). Central lost their opening two matches of the season, but since then manager Paul McGuire’s men have earned three wins and three draws – though […] Manchester Central look to build on their first win of the season last time out when they welcome Hindsford to The Manchester College on Saturday (KO 15:00). Central come into the match having earned their first league victory of the Manchester Football League Premier Division season when they beat fellow newly-promoted side Beechfield United 4-0 […] Manchester Central face a familiar opposition when they take on Beechfield United in the Manchester Football League Premier Division on Thursday at the The Manchester College (KO 20:05). Central played against Beechfield three times last season, when both teams were in Division One, with manager Paul McGuire’s side winning two of the three. Central’s last […] Manchester Central face a tough match away against Walshaw Sports this Friday in the Manchester Football League Premier Division, as they look to build on their positive result last time out (KO 18:45). Central earned their first point of the league season last Saturday when they drew 1-1 with Bolton County. After two disappointing opening […] Manchester Central look to register their first points of the league campaign when they face Bolton County at The Manchester College on Saturday (KO 15:00). After winning promotion last season, Central manager Paul McGuire’s side have found it tough going in their opening two fixtures of the Manchester Football League Premier Division season. Central have […] The team was formed in 1928 by Manchester City Director, John Ayrton and the owner of Belle Vue, John Iles. The club was re-formed in 2015 under its original name Manchester Central. It plays competitive football at the Manchester Regional Arena and Ten Acres Lane and has subsequently joined the non-league pyramid. | Mid | [
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Pyridoxine effect on the antidepressant action of imipramine in albino mice. To evaluate the behavioral effect of pyridoxine on the antidepressant action of imipramine. Male Wistar albino mice of weights 25-35gms were used. Two experiments were carried out; the first on the acute effect of pyridoxine on the duration of immobility, and the second on the sub-chronic effects of pyridoxine alone and in combination with imipramine. In the first experiment, 4 groups of animals received saline, 65, 125, and 250mg/kg pyridoxine. Forced swimming test (FST) was performed 30 minutes after drug administration. In the second experiment, 6 groups of mice were used. The first group received saline, the second group received imipramine 10 mg/kg, the third group received pyridoxine 65mg/kg, the fourth group received pyridoxine 250mg/kg, the fifth group received combined treatment of imipramine and pyridoxine 65 mg/kg, while the sixth group received a combined treatment of imipramine and pyridoxine 250 mg/kg. Administration of drugs was at 24, 5, and one hour before the test. This work was carried out in the Biotechnology Research Center, Twisha, Libya, in June 2007. Acute administration of pyridoxine did not change the duration of immobility compared to the control group. Sub-chronic administration showed that pyridoxine (65mg/kg) did not change the immobility time, while a higher dose of pyridoxine (250mg/kg) decreased the immobility time. Imipramine at 10mg/kg reduces the immobility time significantly. Pyridoxine did not change imipramine action. Pyridoxine alone may produce an antidepressant effect. Pyridoxine in combination with imipramine did not change the imipramine action. | High | [
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A quick glance at London Business School: LBS currently ties for first place as the best international business school in the world (alongside Chicago Booth in the U.S.), according to Bloomberg Businessweek (2012) and fourth place in the world by The Financial Times (2013). London Business School’s Class of 2013 This year’s graduating class had… You’ll find the answer to that question in our newest special report, MBA In Sight: Focus on Finance. If you’re aiming for a future in finance, then you’ll want to attend the schools that will support your finance goal. MBA In Sight: Focus on Finance will introduce you to top programs that put a heavy… A quick glance at University of Chicago’s Booth School of Business: Booth currently ranks in sixth place as one of the best business schools, according to US News & World Report (March 2013). It was ranked #2 for finance. Chicago Booth Class of 2013 and Finance 4031 people applied to Chicago Booth in 2012; 23% were… A quick glance at Michigan Ross currently ranks in 13th place as one of the best business schools, according to US News & World Report (March 2012). It is ranked in 11th place for finance. Ross’s Class of 2014 This year’s incoming class had 502 people in it. The average GMAT score was 703… A quick glance at UCLA Anderson currently ranks in 15th place as one of the best business schools, according to US News & World Report (March 2012). It is ranked in 9th place for finance. Anderson’s Class of 2014 Profile & Finance 3335 people applied to UCLA Anderson in 2012; the target class size was… A quick glance at NYU Stern currently ranks in 11th place as one of the best business schools, according to US News & World Report (March 2012). It is ranked in third place for finance. Stern’s Class of 2014 and Finance 3907 people applied to NYU Stern in 2012; the entering class size was 389…. A quick glance at Stanford Graduate School of Business: It currently ties in first place (with Harvard Business School) as the best business school, according to US News & World Report (March 2012). It is ranked #6 for finance). Stanford GSB Class of 2014 Class Profile: Finance 6716 people applied to Stanford GSB in 2012;… A quick glance at Harvard Business School: HBS currently ranks in first place (tied with Stanford) as the best business school, according to US News & World Report (March 2012). It was ranked as seventh for finance. Harvard Business School Class of 2014 Profile 8,963 people applied to Harvard Business School in 2012; 13% were admitted… A quick glance at Columbia Business School: Columbia currently ranks in eighth place as one of the best business schools, according to US News & World Report (March 2012). It was ranked #4 for finance. Columbia’s Class of 2013 and Finance 6669 people applied to Columbia Business School; 1062 applicants were accepted (16% acceptance rate). The… A quick glance at Wharton: Wharton currently ranks in third place as one of the best business schools, according to US News & World Report (March 2012). For finance, Wharton was ranked as number one. Incoming Wharton Students and Financial Services The class of 2013 has an average of four years of work experience and a… This post about MIT’s Sloan School of Management, focusing on financial services, is part of a series of interviews about top MBA programs called “MBA Career Goals and the B-Schools that Support Them.” Please subscribe to our blog to ensure that you receive all the posts exploring the elements at each school that will help… This post about Dartmouth’s Tuck School of Business, focusing on financial services, is part of a series of interviews about top MBA programs called “MBA Career Goals and the B-Schools that Support Them.” Please subscribe to our blog to ensure that you receive all the posts exploring the elements at each school that will help… | Mid | [
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Q: How to add a sub menu in css template for blog? I want to add a sub menu when hover on it . sub menu should displayed on on right side of it . How to add it ? HTML code: <li><a href='#' style='padding-right: 0px;'>Design  <i class='fa' style='font-size:12px; padding-right: 20px;'></i> </a> <ul class='menus'> <li><a href='http://ravitejasps.blogspot.in/2016/10/serif-and-sans-serif-fonts-what-is.html'>Serif and Sans serif fonts</a></li> <li><a href='http://ravitejasps.blogspot.in/2016/10/spacing.html'>Spacing</a></li> <li><a href='http://ravitejasps.blogspot.in/2016/11/capitalization_3.html'>Capitalization</a></li> <li><a href='http://ravitejasps.blogspot.in/2016/11/legibility.html'>Legibility</a></li> <li><a href='http://ravitejasps.blogspot.in/2016/10/hierarchy-what-is-hierarchy-hierarchy.html'>Hierarchy</a></li> <li><a href='http://ravitejasps.blogspot.in/2016/11/proximity-what-is-proximity-proximity.html'>Proximity</a></li> <li><a href='http://ravitejasps.blogspot.in/2016/11/less-is-more_4.html'>Less is more</a></li> <li><a href='http://ravitejasps.blogspot.in/2016/11/minimalism.html'>Minimalism</a></li> <li><a href='http://ravitejasps.blogspot.in/2016/11/timeless-design.html'>Timeless design</a></li> <li><a href='http://ravitejasps.blogspot.in/2016/11/red-dot-design-awards.html'>Red Dot Design Awards</a></li> <li><a href='http://ravitejasps.blogspot.in/2016/11/golden-ratio.html'>Golden Ratio</a></li> <li><a href='http://ravitejasps.blogspot.in/2016/11/grid-design.html'>Grid design</a></li> <li><a href='http://ravitejasps.blogspot.in/2016/11/grid-design-chandigarh-architecture_87.html'>Grid design: Chandigarh architecture</a></li> <li><a class='ai' href='#'>Alignment</a> <ul class='#menu'> <li><a href='http://ravitejasps.blogspot.in/2016/10/text-alignment.html'>Text alignment</a></li> <li><a href='http://ravitejasps.blogspot.in/2016/11/number-aligment.html'>Number alignment</a></li> </ul> </li> </ul> </li>` Here is my css code /* CSS Main Menu */ #menu-wrapper{background:rgba(46,54,65,0.9);height:50px;width:100%;position:relative;} #menu{color:#fff;height:50px;max-width:1300px;margin:0 auto;} #menu ul,#menu li{margin:0;padding:0;list-style:none;} #menu ul{height:50px} #menu li{float:left;display:inline;position:relative;font-family:arial;font-size:14px;font-weight:400;} #menu li a{color:#fff;} #menu a{display:inline;line-height:50px;padding:17px 20px;text-decoration:none;color:#fff;transition:all 0.2s ease-in-out;}/*margin:0 0 5px 5px*/ #menu li:hover > a{background:#07ACEC;color:#fff;} #menu li a:hover{background:#07ACEC;color:#fff;} #menu input{display:none;margin:0;padding:0;width:80px;height:50px;opacity:0;cursor:pointer} #menu label{font-family:'Open Sans';font-size:30px;font-weight:400;display:none;width:35px;height:51px;line-height:51px;text-align:center} #menu label span{font-size:13px;position:absolute;left:35px} #menu ul.menus{height:auto;overflow:hidden;width:180px;background:#fff;position:absolute;z-index:99;display:none;color:#dadce0;}/*box-shadow:0 0 10px 0 rgba(0,0,0,0.2);*/ #menu ul.menus a{background:#424953;color:#fff;display:block;line-height:20px; padding:10px 20px;}/* padding:10px; border-bottom:1px solid #eee;*/ #menu ul.menus a:hover{color:#53606f;box-shadow:none;} #menu ul.menus li{display:block;width:100%;font-family:'Open Sans';font-size:13px;font-weight:400;text-transform:none;transition:all 0.1s ease-in-out;} #menu ul ul ul { left: 100%; top: 0;} #menu ul:before,ul:after {content: ""; /* 1 */ display: table; /* 2 */} #menu ul:after { clear: both; } #menu ul.menus li:hover{width:100%;} #menu ul.menus li:first-child a{border-top:none;} #menu ul.menus li:last-child a{border-bottom:none;} #menu ul.menus li:hover a {background:#07acec; color:#fff;} #menu li:hover ul.menus{display:block;} #menu .homers a{background:#424953;color:#fff;} #menu .homers a:hover{background:#07acec;color:#fff;} So how would i have to add submenu dropdown on hover ? A: Try by add following css code in your css file and let me know if not work: #menu ul.menus { overflow:visible;} #menu ul ul { display:none; position:absolute; top:0; left:100%; height:auto; width:180px;} #menu ul ul li { float:none;} #menu ul li:hover > ul { display:block;} | Low | [
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www.solaflyklubb.no • User Control Panel • Privacy policy contain a user identifier hereinafter user id and an anonymous session identifier hereinafter session id automatically assigned to you by the phpBB software A third cookie will be created once you have browsed topics within www solaflyklubb no and is used to store which topics have been read thereby improving your user experience We may also create cookies external to the phpBB software whilst browsing www solaflyklubb no though these are outside the scope of this document which is intended to only cover the pages created by the phpBB software The second way in which we collect your information is by what you submit to us This can be and is not limited to posting as an anonymous user hereinafter anonymous posts registering on www solaflyklubb no hereinafter your account and posts submitted by you after registration and whilst logged in hereinafter your posts Your account will at a bare minimum contain a uniquely identifiable name hereinafter your user name a personal password used for logging into your account hereinafter your password and a personal valid e mail address hereinafter your e mail Your information for your account at www solaflyklubb no is protected by data protection laws applicable in the country that hosts us Any information beyond your user name your password and your e mail address required by www solaflyklubb no during the registration process is either mandatory or optional at the discretion of www solaflyklubb no In all cases you have the option of what information in your account is publicly displayed Furthermore within your account you have the option to opt in or opt out of automatically generated e mails from the phpBB software Your password is ciphered a one way hash so that it is secure However it is recommended that you do not reuse | Mid | [
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Q: solving second order linear differential equation Can somebody please show me how to solve the following differential equation: $$ a\ddot{x} + b\dot{x} = c $$ given these initial conditions $x(0) = 2$, $\dot{x}(0) = 0.5$ and $a = 4, b = 1.5$ First I tried to find the homogeneous solution: $$ a\ddot{x} + b\dot{x} = 0 $$ $$ a\ddot{x} = -b\dot{x} $$ then take the integral on both sides: $$ a\frac{dx}{dt} = -bx - C1 $$ $$ \frac{a}{bx+C1}dx = dt $$ integrate again $$ \int\frac{a}{bx+C1}dx = \int dt $$ which should equal to this: $$ \frac{a}{b}log(C1+bx) + C2 = t $$ which results to something like this $$ (C1 + bx)^{\frac{a}{b}} = 10^{t-C2} $$ But I don't know how to proceed in order to solve for x. Using the Laplacetransform I got this far: $$ a(s^2X(s)-sx(0)-\dot{x}(0)) + b(sX(s)-x(0)) = C(s) = 0 $$ $$ as^2X(s)-asx(0)-a\dot{x}(0) + bsX(s)-bx(0) = C(s) = 0 $$ $$ 4s^2X(s)-s8-2 + 1.5sX(s)-3 = C(s) = 0 $$ $$ X(s)(s^2a+sb) = s8+5 $$ $$ X(s) = \frac{s8+5}{s^2a+sb} = \frac{s8}{s^2a+sb}+ \frac{5}{s^2a+sb} $$ But I couldn't find a suitable backtransformation in my formulary. And I am already struggling with the homogenous solution... Can you please give me a hint on how to proceed and which approach to choose? I need to find the time response of x(t). A: You are making this harder than it needs to be, since working with the velocity gives a tracable equation right away. Let $v = \frac{dx}{dt}$, then $$\frac{dv}{dt} = \frac{c - bv}{a} \\ dt = \frac{a}{c - bv} dv\\ t+k = -\frac{a}{b} \ln (c - bv)\\ v=\frac{c-\kappa e^{-\frac{tb}{a}}}{b} $$ Now with $v(0) = \frac12$ we have $$ c-\kappa = \frac{b}{2} \\ \kappa = c-\frac{b}{2} $$ Final step is solving $$\frac{dx}{dt} = \frac{c-\kappa e^{-\frac{tb}{a}}}{b} $$ $$ x = \frac{\kappa}{a} e^{-\frac{tb}{a}} $$ | Mid | [
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Q: ASP.NET MVC4 - Adding to ViewBag in more than one method? Let's say I have a controller with a method that returns a PartialView. If I want to add data to the ViewBag, must it all go inside the one method? For example: public PartialViewResult GetPage() { ViewBag.Example = "Here is some text."; AddMoreToViewBag(); return PartialView(); } private void AddMoreToViewBag() { ViewBag.Example2 = "More text"; } In the above example, will both Example1 and Example2 be available to the PartialView that is returned? A: In the above example, will both Example1 and Example2 be available to the PartialView that is returned? Yes, it is available. | Mid | [
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--- pageid: platform-web title: Web Development layout: docs permalink: /docs/platforms/web/ --- The development of modern websites makes use of both server-side and client-side web technologies. Nuclide makes web developers more productive in this process. * TOC {:toc} ## Server-side Development [Hack](/docs/languages/hack) has first-class support in Nuclide. In conjunction with [HHVM](http://docs.hhvm.com), Hack offers quick development and testing with the comfort of [type safety](https://docs.hhvm.com/hack/typechecker/introduction). Nuclide enhances this by utilizing Hack's information to deliver developer productivity features such as [Autocomplete](/docs/languages/hack/#features__autocomplete) and [inline error checking](/docs/languages/hack/#features__code-diagnostics). If you are a [PHP](http://php.net) developer, Nuclide has [support](/docs/languages/other/#php) for that as well. ## Client-side Development [Flow](/docs/languages/flow) has first-class support in Nuclide. Flow gives you [type safety](http://flowtype.org) as you develop, and Nuclide uses the information provided by Flow to enhance developer productivity. This includes [Jump to Definition](/docs/languages/flow/#jump-to-definition) and [Type Hinting](/docs/languages/flow/#type-hinting). If you are a [JavaScript](https://developer.mozilla.org/en-US/docs/Web/JavaScript) developer, Nuclide has [support](/docs/languages/other/#javascript) for that as well. ## Scripting Nuclide supports many languages to help you write your scripts quicker and error-free. With first-class support for [Hack](/docs/languages/hack) and [Flow](/docs/languages/flow), along with support for [C++](/docs/languages/cpp), Nuclide make you more productive in your script writing. | High | [
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LCS Fat YardTrainer The new LCS Fat YardTrainer Check Cord was designed by our LCS Pro-Staff Trainers who wanted a check rope that was soft on their hands for yard training all day, yet had the thickness so it would not tangle around the dog's legs and be easy to grab. It's 15 feet long and 3/4 inch thick and features a big 1'' Italian bronze snap. Note: These bronze snaps are expensive but outlast brass snaps 3 to 1 and you'll find them on all our Better LCS checkcords and tie-outs. | Mid | [
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Analysis of responses to bradykinin: effects of Hoe-140 in the hindquarters vascular bed of the cat. The mechanisms and receptor subtype mediating vasodilator responses to bradykinin were investigated in the hindquarters vascular bed of the cat under constant flow conditions. Intraarterial injections of bradykinin in doses of 10-1,000 ng into the hindquarters vascular bed caused dose-related decreases in perfusion pressure that were inhibited by Hoe-140, a bradykinin B2-receptor antagonist. Injections of des-Arg9-bradykinin (in doses 10-fold higher than for bradykinin) caused smaller dose-related decreases in hindquarters perfusion pressure that were not blocked by Hoe-140. Administration of atropine, glibenclamide, or cyclooxygenase inhibitors did not alter vasodilator responses to bradykinin, suggesting that activation of muscarinic receptors, ATP-sensitive K+ channels, or prostaglandin release is not involved in the response to the peptide. Administration of N omega-nitro-L-arginine and its methyl ester reduced vasodilator responses to bradykinin, acetylcholine, and substance P, whereas responses to endothelium-independent vasodilator agents were not attenuated. Decreases in systemic arterial pressure and in hindquarters perfusion pressure in response to bradykinin were enhanced by the angiotensin-converting enzyme inhibitors captopril and enalaprilat. These results suggest that hindquarters vasodilator responses to bradykinin are mediated by activation of kinin B2 receptors and in part by the release of nitric oxide. These data also suggest the presence of bradykinin B1 receptors, mediating vasodilation in the hindquarters vascular bed. These results indicate that bradykinin is rapidly inactivated by angiotensin-converting enzyme in the lung and in the hindquarters vascular bed of the cat. | High | [
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665 P.2d 1320 (1983) E.A. STROUT WESTERN REALTY AGENCY, INC., Roosevelt Agency, Plaintiff and Appellant, v. W.C. FOY & SONS, INC., a Utah corporation; W.C. Foy & Sons, a partnership; William W. Foy, Leo B. Foy and John H. Foy, partners, dba W.C. Foy & Sons, Inc., Defendants and Respondents. No. 17784. Supreme Court of Utah. June 16, 1983. *1321 George E. Mangan, Roosevelt, for plaintiff and appellant. Anthony B. Quinn, Merlin O. Baker, Salt Lake City, for defendants and respondents. HALL, Chief Justice: Plaintiff brought this action to recover a real estate commission alleged due by reason of the sale of certain ranch property under a listing agreement. The jury returned a special verdict, finding that plaintiff was not entitled to a commission, not having procured the purchaser under the terms of the agreement. Judgment was entered accordingly and plaintiff appeals, seeking reversal and entry of judgment in its favor as a matter of law, or in the alternative, a new trial. In May, 1974, defendants offered to sell their 8,200-acre ranch in Duchesne County, Utah, to the Ute Indian Tribe, a contiguous landowner. Various representatives and advisors of the Tribe and of the Bureau of Indian Affairs met with the defendants, visited the ranch and indicated an interest in acquiring the property. However, no agreement of sale was reached. In April, 1975, Dean Frandsen, an agent of plaintiff, contacted defendants seeking a listing of the ranch. Frandsen represented that he had a California buyer interested in the property. Subsequently, on April 7, 1975, defendants entered into an open, nonexclusive listing agreement with plaintiff. The agreement provided that if plaintiff were "to procure a purchaser" at the listed price of $646,770, it would be entitled to a selling commission of ten percent of the purchase price. The agreement also reserved the right to defendants to "sell the property to a buyer procured by [themselves] or through another agent and in such case no commission or other charge shall be due" plaintiff. Three days after the agreement was entered into, Frandsen made a sales presentation to the Tribe in the form of a letter. There was a sharp conflict in the evidence presented at trial as to how and why plaintiff became involved in negotiations with the Tribe. Defendant Wendell Foy testified that at the time the listing agreement was entered into, he told Frandsen that the defendants had been negotiating with the Tribe and that they were interested in acquiring the ranch. In his testimony, Frandsen denied that he had been so advised or that he was otherwise aware of the Tribe's interest. Defendant Wendell Foy further testified that the defendants sanctioned Frandsen's involvement in the negotiations with the Tribe only after he represented to them that one Dennis Mower, the Director of Resources of the Tribe, had told him that defendants' negotiations with the Tribe were "dead," but that with his "connections through Mower" he could convince the Tribe to buy the ranch. Subsequently, defendants learned that their negotiations with the Tribe had never been "dead," but in fact had been ongoing since 1974. This was confirmed by the undisputed trial testimony of Dennis Mower, Director of Resources of the Tribe; Adelyn Logan, Realty Officer, Bureau of Indian Affairs; and Ray Smith, Land Operations Officer, Bureau of Indian Affairs. Thereupon, Frandsen was confronted with his alleged misrepresentation, and was thereafter deprived of further *1322 involvement in the ensuing negotiations with the Tribe. Ultimately, the defendants sold the ranch to the Tribe. At the close of all of the evidence, both sides moved for a directed verdict. The motions were denied, and following the jury verdict plaintiff moved for judgment notwithstanding the verdict or, in the alternative, for a new trial. The motions were denied and this appeal followed. Plaintiff designated five points of error on appeal. However, each point bears upon one or the other of two basic contentions that 1) plaintiff was entitled to judgment as a matter of law, and 2) the court's instructions and special verdict failed to adequately present plaintiff's theory of the case to the jury. Plaintiff's contention that the trial court erred in refusing to direct a verdict necessarily fails in light of the sharp conflicts in the evidence. The issue of whether plaintiff was entitled to a sales commission clearly emerged as one of fact, rather than one of law.[1] It is the prerogative of the jury to resolve issues of fact, and the accepted rules of appellate review preclude this Court from substituting its judgment for that of the jury on issues of fact.[2] On appeal, we view the evidence in the light most supportive of the verdict,[3] and assume that the jury believed those aspects of the evidence which sustain its findings and judgment.[4] We will upset a jury verdict only upon a showing that the evidence so clearly preponderates in favor of the appellant that reasonable people would not differ on the outcome of the case.[5] Although in conflict, there is substantial, credible evidence in the record which supports the jury's determination that plaintiff did not procure the Tribe as a purchaser, and thus did not earn a sales commission. As was its prerogative to do, the jury chose to believe the testimony of defendant Wendell Foy and discredit that of Frandsen on the crucial issues as to whether Frandsen was aware of defendants' prior negotiations with the Tribe; whether the Tribe had an ongoing interest in acquiring the ranch; and whether Frandsen represented to defendants that the deal with the Tribe was "dead" and could only be resurrected through his influence with Mower. However, in so doing, as was also its prerogative, the jury saw fit to absolve Frandsen of any false representation. Turning now to plaintiff's remaining contention that the jury was not properly instructed on its theory of the case, defendants' rejoinder is that plaintiff failed to preserve any exceptions to the court's instructions submitted to the jury and, in any event, the instructions were proper and not prejudicial. A party may not assign as error the giving or the failure to give an instruction unless he objects thereto,[6] and the objection must be sufficiently specific to give the trial court notice of the claimed error.[7] While this Court may in its discretion and in the interests of justice review the giving or failure to give an instruction,[8] it is incumbent upon the aggrieved party to present a persuasive reason to invoke the discretion of this Court.[9] In the instant case, plaintiff contends that it was justified in not lodging proper exceptions to the court's instructions to the jury because it was led to believe *1323 that should the jury resolve the issue of "bad faith and conduct" in its favor, the court would then direct a verdict. However, the following portion of the record cited by plaintiff does not bear out its contention. At the time the court was formulating its instructions, plaintiff requested permission to submit a proposed instruction bearing upon the fiduciary duty of a seller to a listing agent, and in granting permission to do so, the following colloquy ensued between the court and counsel: THE COURT: I think those concepts are within the facts and within the disposition of the case based on the answers to the questions that were put. The extent to which that law would have any reflection upon the fact findings that are made by the jury, the Court can apply to the law that is applicable. [Emphasis added.] I think we can get the phrased questions to resolve the conduct whether or not there has been any bad faith conduct, and that's all I am concerned about. MR. MANGAN: Will the Court be instructing the jury, though, on the duty of Mr. Frandsen as the realtor to Mr. Foy? THE COURT: I'm not sure whether I will. I think the instructions that counsel has prepared, as you have seen, there is a fair statement of the fiduciary duty. [Emphasis added.] MR. MANGAN: Is that the one that I submitted? THE COURT: No, the one that Mr. Baker submitted. I'm not sure I remember yours. I guess I read Mr. Baker's last. MR. BAKER: That was taken out of a specific Utah case, your Honor. THE COURT: It appears to me that I had seen that kind of verbage [sic] before surrounding that concept. MR. MANGAN: But it puts it strictly in the sense of a real estate agent. And I think the cases speak themselves to both. I have those cases here, and I'll show them to you. THE COURT: Well, you get what kind of instruction you want me to look at, Mr. Mangan, and then I'll make a decision. Remember, this isn't going to the jury on a general verdict. It's going to be specific interrogatories. MR. MANGAN: I understand that, your Honor. [Emphasis added.] * * * * * * All that is to be gained from the foregoing excerpts from the trial transcript is that the court intended to fulfill its obligation to apply the law to the findings of the jury as they might be expressed in their responses to the interrogatories contained in the special verdict, and to afford counsel for plaintiff the opportunity of submitting proposed jury instructions for approval. It would be wholly unreasonable and improper to interpret those comments so broadly as to relieve counsel of the obligation to take whatever exceptions he may have had to the court's instructions, or to impose an obligation on the court to rule in favor of plaintiff as a matter of law in the face of the jury verdict that plaintiff did not procure the sale. In any event, it appears that the court's instructions presented to the jury are legally sufficient and without prejudice to plaintiff. In its instructions, the court advised the jury that plaintiff's entitlement to a commission hinged upon a showing that it had procured a purchaser.[10] The court then advised the jury of the means to be followed in determining whether plaintiff procured the Tribe as a buyer,[11] and also defined *1324 what is meant by the term "procure."[12] Said instructions comport with the prior pronouncements of this Court as to when a sales commission is due.[13] Plaintiff's theory of the case was of course that it was entitled to recover a sales commission because it had procured the Tribe as a buyer. That theory was clearly and plainly presented to the jury in ordinary, concise and understandable language[14] as is evidenced by the court's instructions Nos. 5, 6 and 7.[15] In regard to the interrogatories submitted to the jury, plaintiff did take exception to Nos. 3 and 7 thereof, contending that since each addressed the issue of procurement, undue emphasis was placed on that issue, which tended to accentuate defendants' theory of the case, and would confuse the jury. While it is true that both interrogatories complained of were directed toward the ultimate fact the jury was called upon to determine, i.e., whether plaintiff procured the sale to the Tribe, it is not to be said that they favored one side or the other. The jury was left free to resolve that issue in favor of either side as their deliberations should dictate. Nor does it appear that the interrogatories in any way tended to confuse. It lies within the broad discretion of the trial court to determine whether special interrogatories are to be used and, if so, the content thereof.[16] In the absence of a showing of an abuse of discretion, the court's actions will not be disturbed.[17] No such abuse of discretion is evident in this case. The record before us reveals that the factual issues and contentions of the parties at trial, together with the applicable law, were set forth in a clear and understandable manner in the court's instructions and interrogatories that were presented to the jury, and that the parties were afforded a fair trial.[18] The judgment is affirmed. Costs to defendants. STEWART, OAKS and DURHAM, JJ., concur. HOWE, J., concurs in the result. NOTES [1] Mel Trimble Real Estate v. Fitzgerald, Utah, 626 P.2d 453 (1981). [2] Watters v. Querry, Utah, 626 P.2d 455 (1981). [3] Cintron v. Milkovich, Utah, 611 P.2d 730 (1980). [4] Gossner v. Dairymen Associates, Inc., Utah, 611 P.2d 713 (1980). [5] Ute-Cal Land Development Corp. v. Sather, Utah, 605 P.2d 1240 (1980). [6] Rule 51, Utah R.Civ.P. [7] Redevelopment Agency of Salt Lake City v. Barrutia, Utah, 526 P.2d 47 (1974). [8] Rule 51, Utah R.Civ.P. [9] Wagner v. Olsen, 25 Utah 2d 366, 482 P.2d 702 (1971). [10] The court's instruction No. 5 reads as follows: Under the terms of the Listing Agreement, the plaintiff to be entitled to a commission had the responsibility to procure a purchaser ready, willing and able to buy the property at the listed price and terms or a price and terms acceptable to the defendants, or that plaintiff was the procuring cause of the sale that was ultimately concluded to the Tribe. The plaintiff has the "Burden of Proof" as in these instructions defined, on the issue of procuring a buyer or the sale as above-set [sic] forth. [11] The court's instruction No. 6 reads as follows: In determining whether the plaintiff did "procure" the Ute Indian Tribe as a buyer of defendants' property, or a sale at a price and terms agreeable to the defendants, you may consider the source, the course of conduct between the plaintiff and the defendants and the Ute Indian Tribe, from and after the listing agreement was signed on April 7, 1975. Such conduct would include correspondence, meetings, and other actions or activities of the parties. [12] The court's instruction No. 7 reads as follows: In this case, under the terms of the listing agreement and the law, the plaintiff, in order to recover any commission, must be the procuring cause of a buyer who was able and willing to buy the property in accordance with the price and terms of the listing agreement, or at a price and terms acceptable to defendants. The plaintiff has the burden to persuade you by the evidence that Dean Frandsen was the procuring cause of the sale of the defendant's property to the Ute Tribe. While it is not essential that the broker's efforts be the sole cause of the sale or transaction, it is essential that they be the predominant and effective cause and not merely an indirect, incidental or contributing cause in one of the links in the chain of causes. [Emphasis added.] [13] Frederick May & Company v. Dunn, 13 Utah 2d 40, 368 P.2d 266 (1962). [14] Gilhespie v. DeJong, Utah, 520 P.2d 878 (1974). [15] Supra nn. 10, 11 & 12. [16] Rule 49, Utah R.Civ.P.; Page v. Utah Home Fire Insurance Company, 15 Utah 2d 257, 391 P.2d 290 (1964). [17] Id. [18] Wagner v. Olsen, supra n. 9. | Low | [
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Q: How to add noise (Gaussian/salt and pepper etc) to image in Python with OpenCV I am wondering if there exists some functions in Python with OpenCV or any other python image processing library that adds Gaussian or salt and pepper noise to an image? For example, in MATLAB there exists straight-forward functions that do the same job. Or, how to add noise to an image using Python with OpenCV? A: The Function adds gaussian , salt-pepper , poisson and speckle noise in an image Parameters ---------- image : ndarray Input image data. Will be converted to float. mode : str One of the following strings, selecting the type of noise to add: 'gauss' Gaussian-distributed additive noise. 'poisson' Poisson-distributed noise generated from the data. 's&p' Replaces random pixels with 0 or 1. 'speckle' Multiplicative noise using out = image + n*image,where n is uniform noise with specified mean & variance. import numpy as np import os import cv2 def noisy(noise_typ,image): if noise_typ == "gauss": row,col,ch= image.shape mean = 0 var = 0.1 sigma = var**0.5 gauss = np.random.normal(mean,sigma,(row,col,ch)) gauss = gauss.reshape(row,col,ch) noisy = image + gauss return noisy elif noise_typ == "s&p": row,col,ch = image.shape s_vs_p = 0.5 amount = 0.004 out = np.copy(image) # Salt mode num_salt = np.ceil(amount * image.size * s_vs_p) coords = [np.random.randint(0, i - 1, int(num_salt)) for i in image.shape] out[coords] = 1 # Pepper mode num_pepper = np.ceil(amount* image.size * (1. - s_vs_p)) coords = [np.random.randint(0, i - 1, int(num_pepper)) for i in image.shape] out[coords] = 0 return out elif noise_typ == "poisson": vals = len(np.unique(image)) vals = 2 ** np.ceil(np.log2(vals)) noisy = np.random.poisson(image * vals) / float(vals) return noisy elif noise_typ =="speckle": row,col,ch = image.shape gauss = np.random.randn(row,col,ch) gauss = gauss.reshape(row,col,ch) noisy = image + image * gauss return noisy A: I don't know is there any method in Python API.But you can use this simple code to add Salt-and-Pepper noise to an image. import numpy as np import random import cv2 def sp_noise(image,prob): ''' Add salt and pepper noise to image prob: Probability of the noise ''' output = np.zeros(image.shape,np.uint8) thres = 1 - prob for i in range(image.shape[0]): for j in range(image.shape[1]): rdn = random.random() if rdn < prob: output[i][j] = 0 elif rdn > thres: output[i][j] = 255 else: output[i][j] = image[i][j] return output image = cv2.imread('image.jpg',0) # Only for grayscale image noise_img = sp_noise(image,0.05) cv2.imwrite('sp_noise.jpg', noise_img) A: just look at cv2.randu() or cv.randn(), it's all pretty similar to matlab already, i guess. let's play a bit ;) : import cv2 import numpy as np >>> im = np.empty((5,5), np.uint8) # needs preallocated input image >>> im array([[248, 168, 58, 2, 1], # uninitialized memory counts as random, too ? fun ;) [ 0, 100, 2, 0, 101], [ 0, 0, 106, 2, 0], [131, 2, 0, 90, 3], [ 0, 100, 1, 0, 83]], dtype=uint8) >>> im = np.zeros((5,5), np.uint8) # seriously now. >>> im array([[0, 0, 0, 0, 0], [0, 0, 0, 0, 0], [0, 0, 0, 0, 0], [0, 0, 0, 0, 0], [0, 0, 0, 0, 0]], dtype=uint8) >>> cv2.randn(im,(0),(99)) # normal array([[ 0, 76, 0, 129, 0], [ 0, 0, 0, 188, 27], [ 0, 152, 0, 0, 0], [ 0, 0, 134, 79, 0], [ 0, 181, 36, 128, 0]], dtype=uint8) >>> cv2.randu(im,(0),(99)) # uniform array([[19, 53, 2, 86, 82], [86, 73, 40, 64, 78], [34, 20, 62, 80, 7], [24, 92, 37, 60, 72], [40, 12, 27, 33, 18]], dtype=uint8) to apply it to an existing image, just generate noise in the desired range, and add it: img = ... noise = ... image = img + noise | Mid | [
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<?xml version="1.0" encoding="UTF-8"?> <!-- Copyright 2015 herd contributors Licensed under the Apache License, Version 2.0 (the "License"); you may not use this file except in compliance with the License. You may obtain a copy of the License at http://www.apache.org/licenses/LICENSE-2.0 Unless required by applicable law or agreed to in writing, software distributed under the License is distributed on an "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. See the License for the specific language governing permissions and limitations under the License. --> <project xmlns="http://maven.apache.org/POM/4.0.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://maven.apache.org/POM/4.0.0 http://maven.apache.org/xsd/maven-4.0.0.xsd"> <modelVersion>4.0.0</modelVersion> <parent> <groupId>org.finra.herd</groupId> <artifactId>herd-tools</artifactId> <version>${revision}</version> </parent> <name>herd pandas python library</name> <!-- groupId and version are inherited from the parent and can be overridden where if needed. --> <artifactId>herd-pandas</artifactId> <build> <plugins> <plugin> <artifactId>maven-resources-plugin</artifactId> <version>3.1.0</version> <executions> <execution> <id>copy-resources</id> <phase>validate</phase> <goals> <goal>copy-resources</goal> </goals> <configuration> <outputDirectory>${project.build.directory}/resources</outputDirectory> <resources> <resource> <directory>${project.basedir}</directory> <filtering>false</filtering> </resource> </resources> </configuration> </execution> </executions> </plugin> <plugin> <groupId>com.google.code.maven-replacer-plugin</groupId> <artifactId>replacer</artifactId> <version>1.5.2</version> <executions> <execution> <phase>process-sources</phase> <goals> <goal>replace</goal> </goals> </execution> </executions> <configuration> <file>${project.build.directory}/resources/setup.py</file> <token>@@Version@@</token> <value>"${herd.python.version}"</value> </configuration> </plugin> <plugin> <groupId>org.codehaus.mojo</groupId> <artifactId>exec-maven-plugin</artifactId> <version>1.6.0</version> <executions> <execution> <id>generate-package</id> <phase>compile</phase> <goals> <goal>exec</goal> </goals> <configuration> <executable>python</executable> <workingDirectory>${project.build.directory}/resources</workingDirectory> <arguments> <argument>setup.py</argument> <argument>sdist</argument> </arguments> </configuration> </execution> </executions> </plugin> </plugins> </build> </project> | Low | [
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List of Houston Rockets statistics and records The Houston Rockets are an American professional basketball franchise based in Houston, Texas. The team plays in the Southwest Division of the Western Conference in the National Basketball Association (NBA). The team was established in 1967, and played in San Diego, California for four years, before relocating to Houston. They have made the playoffs in 25 of their 42 seasons, and won their division and conference four times each; they also won back-to-back NBA championships in 1994 and 1995. They won 22 straight games during the season, the third-longest streak in NBA history. Hakeem Olajuwon, the NBA Finals Most Valuable Player in both of the Rockets' championship seasons, played for the Rockets for 17 years, and is the career leader for the franchise in 9 categories. He also holds the NBA records for blocks in a playoff game, and most points and blocks in a 4-game playoff series. Moses Malone, who played 6 of 19 seasons for the Rockets, had the most points, rebounds, and free throws made in a season for the Rockets, and he also holds the NBA records for most offensive rebounds in a regular season and playoff game. The individual player records section lists the Rockets career leaders in major statistical categories, as well as franchise records for single seasons and games. The team section lists the Rockets' teams that have recorded the highest and lowest totals in a category in a single season and game, and any NBA records that the Rockets have set as a team. Individual records Franchise leaders Bold denotes still active with team. Italic denotes still active but not with team. Points scored (regular season) (as of the end of the 2017–18 season) 1. Hakeem Olajuwon (26,511) 2. Calvin Murphy (17,949) 3. Rudy Tomjanovich (13,383) 4. James Harden (13,014) 5. Elvin Hayes (11,762) 6. Moses Malone (11,119) 7. Yao Ming (9,247) 8. Robert Reid (8,823) 9. Mike Newlin (8,480) 10. Otis Thorpe (8,177) 11. Cuttino Mobley (7,448) 12. Steve Francis (7,281) 13. Tracy McGrady (6,888) 14. Allen Leavell (6,684) 15. Vernon Maxwell (6,002) 16. Ralph Sampson (5,995) 17. Kenny Smith (5,910) 18. Luis Scola (5,597) 19. Rodney McCray (5,059) 20. Sleepy Floyd (5,030) 21. Stu Lantz (4,947) 22. Trevor Ariza (4,863) 23. Lewis Lloyd (4,384) 24. Clyde Drexler (4,155) 25. Buck Johnson (4,139) 26. John Block (4,138) 27. Don Kojis (4,037) 28. John Lucas II (3,756) 29. Kevin Kunnert (3,550) 30. Aaron Brooks (3,465) Other statistics (regular season) (as of July 28, 2018) Individual honors NBA Most Valuable Player Award Moses Malone – 1979, 1982 Hakeem Olajuwon – 1994 James Harden – 2018 NBA Finals MVP Hakeem Olajuwon – 1994, 1995 NBA Scoring Champions Elvin Hayes – 1969 James Harden – 2018, 2019 NBA Defensive Player of the Year Hakeem Olajuwon – 1993, 1994 NBA Rookie of the Year Ralph Sampson – 1984 Steve Francis – 2000 NBA Sixth Man of the Year Eric Gordon – 2017 NBA Most Improved Player Aaron Brooks – 2010 NBA Coach of the Year Tom Nissalke – 1977 Don Chaney – 1991 Mike D'Antoni – 2017 NBA Executive of the Year Ray Patterson – 1977 Daryl Morey – 2018 J. Walter Kennedy Citizenship Award Calvin Murphy – 1979 Dikembe Mutombo – 2009 NBA All-Defensive First Team Hakeem Olajuwon – 1987, 1988, 1990, 1993, 1994 Rodney McCray – 1988 Scottie Pippen – 1999 Patrick Beverley – 2017 NBA All-Defensive Second Team Moses Malone – 1979 Hakeem Olajuwon – 1985, 1991, 1996, 1997 Rodney McCray – 1987 Shane Battier – 2008, 2009 Ron Artest – 2009 Patrick Beverley – 2014 NBA All-Rookie First Team Elvin Hayes – 1969 Calvin Murphy – 1971 Joe Meriweather – 1976 John Lucas – 1977 Ralph Sampson – 1984 Hakeem Olajuwon – 1985 Steve Francis – 2000 Yao Ming – 2003 Luis Scola – 2008 NBA All-Rookie Second Team Robert Horry – 1993 Matt Maloney – 1997 Cuttino Mobley – 1999 Michael Dickerson – 1999 Eddie Griffin – 2002 Luther Head – 2006 Carl Landry – 2008 Chandler Parsons – 2012 All-NBA First Team Moses Malone – 1979, 1982 Hakeem Olajuwon – 1987, 1988, 1989, 1993, 1994, 1997 James Harden – 2014, 2015, 2017, 2018 All-NBA Second Team Moses Malone – 1980, 1981 Ralph Sampson – 1985 Hakeem Olajuwon – 1986, 1990, 1996 Yao Ming – 2007, 2009 Tracy McGrady – 2007 Dwight Howard – 2014 All-NBA Third Team Hakeem Olajuwon – 1991, 1995, 1999 Clyde Drexler – 1995 Yao Ming – 2004, 2006, 2008 Tracy McGrady – 2005, 2008 James Harden – 2013 All-Star Don Kojis – 1968, 1969 Elvin Hayes – 1969–1972 Jack Marin – 1973 Rudy Tomjanovich – 1974–1977, 1979 Moses Malone – 1978–1982 Calvin Murphy – 1979 Ralph Sampson – 1984–1987 Hakeem Olajuwon – 1985–1990, 1992–1997 Otis Thorpe – 1992 Charles Barkley – 1997 Clyde Drexler – 1996, 1997 Steve Francis – 2002–2004 Tracy McGrady – 2005–2007 Yao Ming – 2003–2009, 2011 James Harden – 2013–2018 Dwight Howard – 2014 All-Star head coach Rudy Tomjanovich – 1997 Mike D'Antoni – 2018 All-Star Game MVP Ralph Sampson – 1985 Notes Shooting percentages in basketball are calculated by taking the number of field goals, three-pointers, or free throws attempted, and dividing it by the corresponding number of shots taken. A regulation NBA game is 48 minutes long. Both games went to triple overtime. The record only applies for a player that had 10 or more field goal attempts in a game. The record only applies for a player that had 5 or more three-point field goals made in a game. This means that the Rockets made 61 fields goals out of 89 attempted. Drexler shares this record with 10 other players. Olajuwon shares this record with Mark Eaton. This record was achieved in one other game, between the New Jersey Nets and the Portland Trail Blazers. The Rockets share this record with the Washington Wizards. The Rockets share this record with the Orlando Magic (January 19, 2009) The Rockets share this record with the Denver Nuggets (February 13, 2017). References General Specific External links Rockets.com Houston Rockets official site Houston Rockets Statistics at Basketball-Reference.com Category:Houston Rockets lists Category:National Basketball Association accomplishments and records by team | Mid | [
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Tuesday, November 04, 2008 " ... Masquerading as opposition and dissident opinion, we have racist 'trufing' perhaps of the John Birch variey morphed via the leftist elite into the UNHOLY ALLIANCE of true stupidity. ... "Right still wooing left: Mark Weber, director of the notorious, Holocaust-denying Institute for Historical Review, addressed a peace conference in August, and was reportedly "well-received." This report is from the IHR web site: Weber Addresses Peace Conference in Baltimore Mark Weber addressed a conference to promote peace and cross-cultural understanding on August 16 in suburban Baltimore. In a crisply delivered and well-received address, the IHR director spoke about the motives behind the US invasion of Iraq, the harmful consequences of America’s "blank check" support for Israel, the Jewish-Zionist grip on US foreign policy, the danger of new wars, and the prospects for an effective peace movement. The event was organized by an Islamic association, Jamaat Al-Muslimeen. Among the other speakers were: Ramsey Clark, former US Attorney General; Charles E. Carlson, director of "We Hold These Truths," a Christian organization for peace and justice; and, Dr. Kaukab Siddique, MC and publisher of New Trend Magazine. Critics of a speaker widely viewed as one of the nation’s most prominent deniers of the Holocaust say they will counter his talk in Eugene on Friday with a competing event and a later symposium. Mark Weber, director of the Institute for Historical Review (out of Willis Carto and the 'Liberty Lobby'), will speak on “The Israel Lobby.” His visit comes at the invitation of the Pacifica Forum, a local discussion group founded by retired University of Oregon professor Orval Etter (Orval Etter, associate professor emeritus. B.S., 1937, J.D., 1939, Oregon. (1939)). Calling the Kennedy School of Govt at Harvard, we have a message for Herr Doktor Smears and Gruppenfuhrer Waltheimer. Advertisements for the event feature the image of a snake in the shape of a Star of David with the legend "The Israel Lobby: How Powerful Is It?" Weber, a historian who grew up in Portland, describes himself as a Holocaust revisionist. But detractors point to Weber’s own writings in labeling him a white supremacist, racist and anti-Semite. “People may think I’m wrong or I’m right, but they should have a chance to hear what I have to say,” Weber said in a telephone interview from his institute’s office in Newport Beach, Calif. Can you imagine? Any view is due equal consideration? Is this the adulterated thinking of university symposiums? | Low | [
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Q: What is the definition of this statistic? For a data set that is Gaussian distributed, $\sigma$ defines the standard-deviation of the distribution. My question is, what is the correct indention or terminology for the following: $$\frac{\sigma}{\sqrt{2N-2}} \text{.}$$ My interpretation is that it is the "error" in the standard deviation, $\sigma$. Is this a correct way to view this? A: It's important to distinguish between the true population value of a parameter of a statistical distribution and the estimate of that value obtained from a sample of size $N$. The symbol $\sigma$ is conventionally used to represent the population standard deviation, the square root of the population variance $\sigma^2$. A sample estimate of the variance is conventionally represented as $s^2$ and a sample estimate of the standard deviation as $s$. This question shows the formula for the standard error of estimates of the variance, $s^2$, when sampling from a normal distribution. The answer to that question shows a way to convert such standard error estimates of $s^2$ to standard error estimates of $s$ that holds in the limit of large sample sizes for sampling from any of a large class of distributions. A bit of math shows that if you replace $\sigma$ in your formula with $s$ you have the corresponding formula for the standard error of the sample standard deviation in the case of a normal distribution. | Mid | [
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Sherpa team aims for record Everest winter ascent A team of four Sherpas is setting off on Monday to attempt a record winter ascent of Mount Everest in just five days, which would also be the first winter climb of the peak in more than quarter of a century. The last successful winter ascent was in 1993 by a Japanese team. "A winter speed climbing expedition has not happened yet and so we are attempting a new record," team leader Tashi Lakpa Sherpa, who has summited Everest eight times, told reporters. Sherpa, 34, will not be using supplemental oxygen. Only one climber has previously ascended the peak in winter without supplemental oxygen: a Nepali mountaineer in December 1987. Sherpa will be joined by three other climbers -- Pasang Nurbu Sherpa, Ming Temba Sherpa and Halung Dorchi Sherpa -- who all have at least two Everest summits under their belt. "I know the mountain ... We are fully prepared and we have acclimatised. The biggest preparation to minimise risk on the mountain is acclimatisation," Sherpa said. The Nepali climbers will be joining two other teams at Everest Base Camp who have been waiting for the right weather conditions. Spanish alpinist Alex Txikon and his team and German climber Jost Kobusch are also hoping to break the spell of unsuccessful winter expeditions on Everest. Temperatures near the summit of Everest in winter regularly plunge below minus 40 degrees Celsius (minus 40 degrees Fahrenheit), while strong winds make it even riskier. In those conditions exposed skin freezes in less than five minutes, putting climbers in serious danger of frostbite. Hundreds of climbers flock to Everest each year but most attempt the climb during a narrow window of calm weather between late April and May. Last year's traffic-clogged spring climbing season saw a record 885 people summit Everest, 644 of them from the south and 241 from the northern flank in Tibet. The season ended with 11 deaths on the mountain, with at least four blamed on overcrowding. Autumn summits last year were thwarted by a serac -- a block of glacial ice -- hanging dangerously above the already treacherous Khumbu icefall that climbers have to cross to reach Camp 1. Nepal is home to eight of the world's 14 highest peaks and foreign climbers who flock to its mountains are a major source of revenue for the country. | Mid | [
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Bedford, Wyoming Bedford is a census-designated place (CDP) in Lincoln County, Wyoming, United States. The population was 201 at the 2010 census. History The first settlement at Bedford was made in 1890. A post office called Bedford was established in 1898, and remained in operation until 1966. The community was named after Bedford, in Virginia. Geography Bedford is located at (42.897527, −110.936463). It located in Star Valley, a grassland valley surrounded by forested mountains. According to the United States Census Bureau, the CDP has a total area of 1.3 square miles (3.4 km2), all of it land. Demographics As of the census of 2000, there were 169 people, 63 households, and 49 families residing in the CDP. The population density was 75.5 people per square mile (29.1/km2). There were 73 housing units at an average density of 32.6/sq mi (12.6/km2). The racial makeup of the CDP was 97.04% White, 1.18% Native American, 0.59% from other races, and 1.18% from two or more races. Hispanic or Latino of any race were 1.18% of the population. There were 63 households, out of which 23.8% had children under the age of 18 living with them, 69.8% were married couples living together, 6.3% had a female householder with no husband present, and 22.2% were non-families. 15.9% of all households were made up of individuals, and 12.7% had someone living alone who was 65 years of age or older. The average household size was 2.68, and the average family size was 3.04. In the CDP, the population was spread out, with 28.4% under the age of 18, 3.6% from 18 to 24, 20.1% from 25 to 44, 26.6% from 45 to 64, and 21.3% who were 65 years of age or older. The median age was 42 years. For every 100 females, there were 89.9 males. For every 100 females age 18 and over, there were 101.7 males. The median income for a household in the CDP was $40,469, and the median income for a family was $40,625. Males had a median income of $36,176 versus $20,625 for females. The per capita income for the CDP was $29,976. None of the population or families were below the poverty line. Education Public education in the community of Bedford is provided by Lincoln County School District #2. References Category:Census-designated places in Lincoln County, Wyoming Category:Census-designated places in Wyoming | Mid | [
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Q: width of vertical margin which is not set I have a question about settings of margin in this case: http://jsfiddle.net/s38Ar/6/ As you see there is vertical margin between two columns. I would like to know its width and why it looks like this, because I want to set it myself precisely. Setting float:left to .column is not acceptable because theme2 should align down to theme4 (as you can see) CSS body{background-color:#0d5697;} .selborder{border:#d7e51c;} p{font-size:1em;color:white;} #header{height: 50px;background-color: #666;margin-bottom: 10px;} h1{font-size:1.5em;color:#dae645;} @media screen and (max-width: 800px) and (min-width: 448px) { #galeria{width:100%;height: 100%;margin:0 auto;} #gutter{background-color:white;display:inline-block;width:3%;height:100%;margin-bottom:10px;float:left;display: inline-block;} .column2{height:100%;width:94%;float:left;} .column{width:49%;background-color:red;vertical-align:bottom;display:inline-block;} .work{vertical-align:bottom;} .komorka{width:100%;height:100%;} .cl2{clear:both;} } HTML <body> <div id="header"></div> <div id="galeria"> <div id="gutter"></div> <div class="column2" id="m_col"> <div class="column" id="col1"><div class="work" id="work1"> <h1 class="komorka"> theme1 more more more more more more more more more more more theme</h1><img id="paint" class="komorka" src="projekty/asd.png"></img><p class="komorka">1But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual teachings of the great explorer of the truth, the master-builder of human happiness.</p> </div></div> <div class="column" id="col2"><div class="work" id="work2"> <h1 class="komorka">theme 2</h1><img class="komorka" id="paint" src="projekty/asd.png"></img><p class="komorka">1But pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual teachings of the great explorer of the truth, the master-builder of human happiness.</p> </div></div> <div class="column cl2" id="col3"><div class="work" id="work3"> <h1 class="komorka">theme 3</h1><img class="komorka" id="paint" src="projekty/asd.png"></img><p class="komorka">1But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual teachings of the great explorer of the truth, the master-builder of human happiness.</p> </div></div> <div class="column" id="col4"><div class="work" id="work4"> <h1 class="komorka">theme 4</h1><img class="komorka" id="paint" src="projekty/asd.png"></img><p class="komorka">1But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual teachings of the great explorer of the truth, the master-builder of human happiness.</p> </div></div> <div class="column" id="col5"><div class="work" id="work5"> <h1 class="komorka">theme 5</h1><img class="komorka" id="paint" src="projekty/asd.png"></img><p class="komorka">1But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual teachings of the great explorer of the truth, the master-builder of human happiness.</p> </div></div> </div> </div> <div id="footer"></div> </body> A: That is due to the inline-block display, it turns both columns into inline elements (like a span or an a). The solution in your case is to manually "remove" the right margin for the left column, like this (just an example for the first two columns): #col1 { margin-right: -4px; } Another solution (less practical, but works), is to remove the space between divs in the HTML code, this makes the columns fit nicelly, but with dynamic code that might be complicated to get. I made this example for the first two columns: http://jsfiddle.net/jackJoe/s38Ar/7/ | Low | [
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Effect of lipolytic activity of Candida adriatica, Candida diddensiae and Yamadazyma terventina on the acidity of extra-virgin olive oil with a different polyphenol and water content. Previous microbiological research demonstrated the presence of a rich micro-flora composed mainly of yeasts in the suspended fraction of freshly produced olive oil. Some of the yeasts are considered harmful as they can damage the quality of the olive oil through the hydrolysis of the triacylglycerols. Present research has demonstrated that the lipolytic activity of some lipase-producer strains belonging to a yeast species called Candida adriatica, Candida diddensiae and Yamadazyma terventina can be modulated by the water and the polyphenol content of olive oil. Laboratory tests highlighted a substantial increase in free fatty acid in the inoculated olive oil characterized by high water content and low polyphenol concentration. The acidity of the olive oil samples containing 0.06% and 0.31% of water increased significantly by 33% in the lipase-producer yeast strains tested during a period of 2 weeks of incubation at 30 °C. All other yeasts showed strong lipolytic activity in the presence of 1.31% of water - the only exception to this was the C. adriatica 1985 strain. The phenolic compounds typical of olive oil represent another important factor able to condition the viability and the lipolytic activity of the lipase-producer yeasts. From the tests performed on the olive oil characterized by an increasing content of total polyphenols equal to 84, 150 and 510 mg per kg of oil, the percentage of the lipase-producer yeasts able to hydrolyse the triacylglycerols was respectively 100%, 67% and 11%. | Mid | [
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--- abstract: 'Axons are linear structures of nerve cells that can range from a few tens of micrometers up to meters in length. In addition to external cues, the length of an axon is also regulated by unknown internal mechanisms. Molecular motors have been suggested to generate oscillations with an axon-length dependent frequency that could be used to measure an axon’s extension. Here, we present a mechanism for determining the axon length that couples the mechanical properties of an axon to the spectral decomposition of the oscillatory signal.' author: - Frederic Folz - Lukas Wettmann - Giovanna Morigi - Karsten Kruse title: 'The sound of an axon’s growth' --- \[key\] In order to assure proper function, the size of a biological system typically needs to be regulated. There is currently no general understanding of the underlying mechanisms. Best studied are processes based on gradients for setting the extension of linear structures. Prominent examples are provided by the length of cytoskeletal filaments [@Varga:2006er; @Varga:2009jy; @Johann:2012kk; @Melbinger:2012hp; @Erlenkamper:2013cy; @Mohapatra:2015cc; @Mohapatra:2016kq; @Fritzsche:2016fx] and the extension of antiparallel microtubule overlaps [@Channels:2008io; @Johann:2015da; @Braun:2017hx]. In addition, length-dependent mechanical forces can play a role as has been suggested for setting the size of stereocilia [@Prost2007]. Finally, oscillations are involved in positioning the division plane of some bacteria [@Loose:2011dd; @Wettmann:2018bp] and thereby determine the size of the daughter cells. They may be viewed as a specific case of cavity resonances of chemical waves that have been proposed to provide a general mechanism for size determination of biological structures [@Laughlin:2015hm]. Axons are linear structures along which electrical signals emanating from the body (soma) of a nerve cell are transported to other cells. The length of an axon can vary from a few micrometers up to meters. It is set in part by extrinsic mechanisms, for example, stretch growth: axons that have connected to other cells are experiencing mechanical tension as the organism is growing, which induces axonal extension [@Athamneh:2015ba]. Prior to making contact with other cells and driven by a structure called the growth cone, axons extend at their tip. Growth cones are guided in part by external physical [@Koser:2016ks] and chemical cues [@Erskine:2007dw]. In addition, there are intrinsic mechanisms to set the axon length that are notably used in early stages of organismal development [@Albus:2013es].  Illustration of axon length regulation. Motors transport signals $I$ and $O$ along microtubules at velocity $v$, respectively, from the soma to the growth cone and *vice versa*. Activation of $O$-transport in the growth cone by $I$ and suppression of $I$ at the soma by $O$ generate oscillations with a frequency depending on the axon length $L$. The total influx of $I$ comprises both a constant $J_0$ corresponding to the maximal influx of motors and the inhibitory effect of $O$. Furthermore, the signal $I$ also stimulates actin polymerization leading to growth cone extension, as well as inhibition of the response $R$. In turn, $R$ induces actin network contraction leading to growth cone retraction. The extending and contracting actin networks are drawn separately for clarity, but can be colocalized. Lines with arrow heads indicate activation/stimulation, lines with blunt ends inhibition.](FolzetalFig1.pdf){width="45.00000%"} It has been shown that transport by molecular motors – with kinesins moving from the soma to the axon tip and cytoplasmic dynein in the opposite direction – is essential for intrinsic axonal length regulation [@Myers:2007ig; @Rishal:2012jg; @Perry:2016he]. However, the precise role of the motors in this process is currently unknown. Similar to motor-dependent length-regulation of filaments [@Varga:2006er; @Varga:2009jy; @Johann:2012kk; @Melbinger:2012hp; @Mohapatra:2015cc], one possibility is that they generate a gradient along the axon. Yet, a gradient-based mechanism is unlikely to operate over more than a few micrometers in cells, whereas in developing embryos, axons up to a few hundred micrometers can emerge [@Albus:2013es]. Furthermore, decreased motor concentrations would imply shortened axons. However, the opposite is observed [@Myers:2007ig; @Rishal:2012jg]. These considerations have led to the proposal that interactions between motors moving in opposite directions along the axon generate an oscillating signal with a length-dependent frequency [@Rishal:2012jg]. Indeed, if kinesins transported some signaling molecule to the tip, where it initiated dynein-mediated transport of another signalling molecule that in turn stopped the original chemical signal at the soma, then the concentrations of these factors at the growth cone and at the soma can oscillate [@Karamched:2015ha], see Fig. \[fig:schema\]. For motors with a constant velocity the associated period would increase proportional to the axon length. However, it is not clear how this frequency-dependence could be used for length regulation. One proposition is that there is a network generating a frequency-dependent average of some signaling molecule coupled to a switch turning off further axonal growth as a certain concentration threshold and therefore length is reached [@Bressloff:2015gg]. The actual growth dynamics of an axon regulated by length-dependent oscillations has not yet been studied. Here, we propose a mechanism for this regulation that couples the oscillations to the axon’s mechanical properties. Axons are known to be under mechanical tension: on one hand, the growth cone pulls on the axon [@Bray:1979tg], on the other hand, the axon itself generates contractile mechanical stress by the actin cytoskeleton [@Ahmad:2000wv; @Bernal:2007gx]. The regulation of cytoskeletal stresses has been suggested to generate bouts of elongation and retraction [@Baas:2001kk]. The oscillations can be analyzed through differential equations with delayed feedback [@Karamched:2015ha]. We start from these equations and explicitly include the axon growth dynamics, obtaining a set of equations with a state-dependent delay. We show that our mechanism, rather than reading out the oscillation frequency, exploits the information contained in the signal’s spectral composition for regulating axon growth and length. Notably, we find regions in parameter space where a reduction of the motor concentration leads to an increase in the final axon length, consistent with experimental findings [@Myers:2007ig; @Rishal:2012jg]. Let us begin our discussion by noting that, typically, the cellular response to a chemical signal shows a sigmoidal dose-response curve [@Alon06:nn]. It is often given in terms of a Hill function $$\begin{aligned} f_\kappa\left(c\right)&=\frac{c^n}{\kappa^n+c^n} \end{aligned}$$ with Hill coefficient $n$ and half-concentration $\kappa$. For an oscillating chemical signal, the average response is independent of the signal’s period $T$: Let $c_I$ denote the concentration of an incoming signaling molecule with $c_I(t+T)=c_I(t)$. The response $c_R$ is then given by $$\begin{aligned} \label{eq:cRdot} \dot{c}_R &= J_R(1-f_\kappa\left(c_I\right)) - \gamma_R c_R , \end{aligned}$$ where $J_R$ is the coupling constant between $c_I$ and $c_R$ and $\gamma_R$ is the response’s decay rate. In the following we will scale the concentrations by $\kappa$ and denote them by the same symbols as before. The average response is then $\langle c_R\rangle \equiv \frac{1}{T}\int_0^T c_R(t)\;\mathrm{d}t=\bar{J}_R(1-\langle f_1\left(c_I\right)\rangle)$, which is scaled by the dimensionless parameter $\bar{J}_R\equiv J_R/(\gamma_R\kappa)$. It holds that $\frac{1}{T}\int_0^{T} f_1\left(c_I( t)\right) \;\mathrm{d}t=\frac{\beta}{T}\int_0^{T/\beta} f_1\left(c_I(\beta t)\right) \;\mathrm{d}t$ for any $\beta>0$ showing that $\langle c_R\rangle$ is independent of the oscillation period. This general result can be illustrated in the limit $n\to\infty$, when the Hill function turns into a Heaviside function, and one can determine the time dependence of $c_R$ explicitly. Let the input signal be some oscillatory function with exactly one minimum and one maximum per period $T$ and let $t=0$ and $t=t_\times$ be the times, when the input signal equals the threshold, such that $c_I(t)>1$ for $0\le t< t_\times$ and $c_I(t)<1$ for $t_\times\le t<T$. Then the average is given by $$\begin{aligned} \label{eq:cR:ave} \langle c_R\rangle &=\bar{J}_R\left(1-\frac{t_\times}{T}\right)\,. \end{aligned}$$ Apart from the coupling constant $\bar{J}_R$, $\langle c_R\rangle$ only depends on the fraction of the period during which the incoming signal $c_I$ is larger than $1$, but is independent of the period. Whereas $\langle c_R\rangle$ does not depend on the frequency of $c_I$, the form, i.e., the spectrum of $c_R$ does. In turn, $\langle c_R\rangle$ typically depends on the spectrum of $c_I$. This is easily seen if $f_\kappa$ is a Heaviside function as in the previous paragraph: As long as $\min c_I<\kappa<\max c_I$, a change in the spectrum of $c_I$ typically changes the fraction of time $c_I>\kappa$ and hence $\langle c_R\rangle$. Consequently, by first transforming the frequency variation of a signal $O$ into a variation of the shape of the incoming signal $I$ via a process similar to Eq. (\[eq:cRdot\]) and then reading out its shape via Eq. (\[eq:cRdot\]), variations in frequency can be ultimately turned into a variation of the average value of the response $R$.  Two-step transformation of a periodic signal into a frequency-dependent average response, Eqs. (\[eq:cRdot\]) and (\[eq:cGdot\]). a) Dynamics of the response $c_R$ as a function of time and corresponding mean value $\langle c_R\rangle$ for two different frequencies of a sinusoidal oscillatory signal $O$, $c_{O}(t) = \bar J_R(1+\sin(2 \pi t/T))/2$. b) Response average value $\langle c_R\rangle$ as a function of the oscillatory signal frequency for two different Hill coefficients. Full line represents the analytic expression Eq. (\[eq:cR:ave\]) with $t_\times$ replaced by $t_>$. Parameter values are $J_R = J_I = 55 \times 10^{-5} \,\upmu$m$^{-1}$s$^{-1}$, $\kappa = 2 \times 10^{-2} \,\upmu$m$^{-1}$, $\gamma = 10^{-2}\,$s$^{-1}$ as well as $n=4$ (a) and $n=4$ (dotted line with circles) and $n=50$ (full line with circles) in panel (b).](FolzetalFig2.pdf){width="47.00000%"} To give a specific illustration of this mechanism, consider an oscillatory signal $O$, which feeds into $I$ through $$\begin{aligned} \label{eq:cGdot} \dot c_I &= J_I \left(1-f_\kappa(c_O)\right)-\gamma_Ic_I, \end{aligned}$$ where $J_I$ is the coupling constant between $O$ and $I$ and $\gamma_I$ is the decay rate of the incoming signal. Furthermore, we used the same sigmoidal function $f_\kappa$ in Eqs. (\[eq:cRdot\]) and (\[eq:cGdot\]), but our general results do not rely on these specific choices. We will also choose $J_I=J_R$ and $\gamma_I=\gamma_R\equiv\gamma$ to not blur the general mechanisms by a multitude of parameters. As above we will scale the densities by $\kappa$. As anticipated, the incoming signal $I$ responds to frequency changes in $O$ by variations of its shape, see Fig. \[fig:averageAsFunctionOfFrequency\]a. Furthermore, the average value of the eventual response $R$ varies with the frequency of $O$, see Fig. \[fig:averageAsFunctionOfFrequency\]b. In case $f_\kappa$ is a Heaviside function, the average of $c_R$ as a function of the period $T$ of $c_O$ takes the same form as Eq. with the replacement $t_\times\to t_{>}$. Here, $t_{>}$ is the length of the time interval during which $c_I>1$, where $t_{>}>0$ requires $\bar{J}_I>1$. The value of $t_>$ is determined by a transcendent equation, which we omit here. The average response increases with $T$ and $\langle c_R\rangle\to \bar{J}_R (1 - t_>/T)$ for $n\to\infty$. Having established a mechanism for reading out the frequency of the incoming signal, we now return to axon length regulation. As mentioned in the introduction, motors moving in opposite directions and carrying motor-transport activating or inhibiting signals can generate axon-length dependent oscillations. Specifically, let $I$ denote a signal released from the soma and transported into the growth cone. Its concentration at the growth cone is denoted by $c_I(t)$. In addition to eliciting the response $R$, it also triggers transport of an outgoing signal $O$ from the growth cone to the soma. There, $O$ suppresses further transport of $I$. The concentration of $O$ at the soma is denoted by $c_O(t)$. This dynamics can be captured as in Ref. [@Karamched:2015ha] by the following delay-differential equations $$\begin{aligned} \label{eq:cIdot} \dot c_I(t) & = J_0 - J_I f_\kappa\left(c_O(t-\tau)\right) - \gamma_I c_I(t) \\ \label{eq:cOdot} \dot c_O(t) & = J_O f_\kappa\left(c_I(t-\tau)\right)-\gamma_O c_O(t) . \end{aligned}$$ The delay $\tau=L/v$ accounts for the time motors need to transport cargo along an axon of length $L$ at a velocity $v$, which we assume for simplicity to be the same for both kinds of motors. Note that for $\tau=0$, Eq. (\[eq:cIdot\]) is the same as Eq. (\[eq:cGdot\]) if $J_0=J_I$. The incoming signal decays at rate $\gamma_I$ at the growth cone and the outgoing signal at rate $\gamma_O$ at the soma. $J_0$ is the maximal incoming flux of signal $I$ and $J_I\le J_0$ as well as $J_O$ denote the respective coupling constants between $O$ and $I$. To avoid unnecessary complications, we consider again the same sigmoidal function $f_\kappa$ as in Eqs. (\[eq:cRdot\]) and (\[eq:cGdot\]) and focus on the case $\gamma_I=\gamma_O\equiv\gamma$ and $J_0=J_I=J_O\equiv J$. For fixed length $L$, a linear stability analysis of the stationary state $c_{I,0}$ and $c_{O,0}$ of Eqs. (\[eq:cIdot\]) and (\[eq:cOdot\]) shows that the system undergoes a Hopf-bifurcation when the parameters fulfil $$\begin{aligned} \label{Lmin} \bar{J}\sin\left(\gamma\tau\sqrt{\bar{J}^2-1}\right)&=1, \end{aligned}$$ where $\bar J=\sqrt{\alpha} J/(\kappa\gamma)$ and $\alpha=\langle f_1'(c_O)\rangle\langle f_1'(c_I)\rangle$ [@Karamched:2015ha]. In particular, $f_1'(x)=df_1(x)/dx$ and the mean values are taken at the instability point $c_I=c_I^*$, $c_O=c_O^*$, cf. Supplementary Material (S.M.). This equation can only be fulfilled if $\bar{J}>1$. The linear stability analysis also shows that there is a minimal axon length $L_\mathrm{min}=v\tau_\mathrm{min}$, below which the system does not oscillate, which is in agreement with numerical solutions of Eqs. (\[eq:cIdot\]) and (\[eq:cOdot\]), see Fig. \[fig:motorOscillations\]a. The frequency $\omega_\mathrm{min}$ at this critical axon length is finite and fulfils $$\begin{aligned} \cot\left(\omega_\mathrm{min}\tau_\mathrm{min}\right)&=\frac{\omega_\mathrm{min}}{\gamma}\,. \end{aligned}$$ Remarkably, this relation between the axon length and the oscillation frequency also determines the frequency of the full nonlinear oscillations, see Fig. \[fig:motorOscillations\]b. As a function of the axon length $L$ it is approximately given by $$\begin{aligned} \label{eq:omegaAsFunctionOfL} \omega\sim\frac{1}{\sqrt{\frac{L}{v}\left(\frac{L}{3v}+\gamma^{-1}\right)}}. \end{aligned}$$ For $L\gamma\gg v$, we have $\omega \approx \sqrt{3}v/L$, which is the solution of a wave equation with a rescaled sound velocity. In the opposite limit, the frequency scales as $\omega\approx \sqrt{v\gamma/L}$.  Motor-induced oscillations for fixed axon length. a) Oscillation of the incoming and outgoing signals $I$ and $O$, respectively, obtained by solving Eqs. (\[eq:cIdot\]) and (\[eq:cOdot\]). b) Frequency of the oscillations generated by Eqs. (\[eq:cIdot\]) and (\[eq:cOdot\]). The full line is obtained from Eq. (\[eq:omegaAsFunctionOfL\]). Parameter values as in Fig. \[fig:averageAsFunctionOfFrequency\] and $J_0 = J_O = J_I$, $\gamma_O = \gamma_I = \gamma$ as well as $n = 4$ (a) and $n=4$ (squares) and $n=50$ (circles) in panel (b).](FolzetalFig3.png){width="50.00000%"} Whereas the previous analysis was for a fixed axon length, we will now consider $L$ to be a dynamic variable. The axon length is regulated by two processes: an extension of the growth cone and a shortening of the axon due to contractile stresses [@Ahmad:2000wv; @Bernal:2007gx]. The growth cone moves forward by a process similar to mesenchymal cell migration on a flat substrate: Extension of the leading edge is driven by the polymerization of actin, which is anchored to a large actin network and thus able to exert protruding forces on the membrane. The protrusion velocity is regulated by various processes. We assume here that chemical regulation through signal $I$ dominates and write for the protrusion velocity $v_gc_I$. We notably neglect an effect of membrane tension on the protrusion velocity [@Mueller:2017br]. The contractile stresses that are generated by molecular motors in the axon and the growth cone can be captured phenomenologically by a term $\zeta\Delta\mu$ [@Kruse:2004il]. Here, $\Delta\mu\equiv\mu_\mathrm{ATP}-\mu_\mathrm{ADP}-\mu_\mathrm{P}$, where $\mu_\mathrm{ATP}$ is the chemical potential of Adenosine-triphosphate, $\mu_\mathrm{ADP}$ that of Adenosine-diphosphate, and $\mu_\mathrm{P}$ that of inorganic phosphate, such that $\Delta\mu$ is the chemical energy liberated during an event of ATP-hydrolysis. The phenomenological coefficient $\zeta$ describes the coupling of the liberated chemical energy to the mechanical stress generated. For contractile stresses $\zeta<0$. The phenomenological coefficient $\zeta$ depends on regulatory signals [@Bois:2011kx]. In particular, we assume $\zeta\equiv\zeta(c_R)$. Contractile stresses tend to reduce the distance between the cell body and the growth cone. We assume the cell body to be anchored to the substrate, such that contractile stresses are balanced by dissipative forces as the growth cone retracts. The latter can be written as $\xi \dot{x}_\mathrm{gc}=\zeta\Delta\mu$, where $x_\mathrm{gc}$ denotes the position of the growth cone and which we identify with the axon length $L$. Assuming a linear dependence of $\zeta$ on $c_R$, $\zeta=\zeta_1c_R$, and adding the growth cone protrusion velocity to the velocity due to contraction, we arrive at $$\begin{aligned} \label{eq:Ldot} \dot{L}&=v_gc_I-v_sc_R, \end{aligned}$$ where $v_s=-\zeta_1\Delta\mu/\xi>0$. The response $R$ still depends on $I$ through Eq. (\[eq:cRdot\]). We will scale the length by $L_\mathrm{min}$ and concentrations by $\kappa$, while keeping the same notation for the axon length as well as for the growth and shrinkage velocities. Furthermore, we take $\gamma_R=\gamma$. In Figure \[fig:exampleLengthRegulation\]a, we present an example of the solution to the dynamic equations (\[eq:cRdot\]), (\[eq:cIdot\]), (\[eq:cOdot\]), and (\[eq:Ldot\]). Starting from length zero, the length increases and eventually oscillates with an amplitude that is less than $1\%$ of the average length. The final average length decreases with an increasing coupling parameter $J_R$, Fig. \[fig:exampleLengthRegulation\]b. This is because an increase of the coupling between the incoming signal and actomyosin contractility will increase the latter, which opposes the extension of the axon. A similar effect is observed when reducing the actomyosin activity, which is generally achieved by decreasing $\zeta_1\Delta\mu$ . Importantly, in Fig. \[fig:exampleLengthRegulation\]c it is visible that for sufficiently small values of $J_0$ the stationary length increases with decreasing $J_0$, that is with decreasing kinesin motor concentration. This is consistent with experimental findings [@Myers:2007ig; @Rishal:2012jg]. Only beyond a certain critical value of $J_0$ the average final length increases with an increasing motor concentration [^1]. An increase of the axon lengths has been also observed when the dynein concentration is reduced [@Rishal:2012jg]. Accordingly, our model shows an increase in the stationary length, when the parameter $J_O$ is reduced, see S.M.  Axon length dynamics. a) Solution to the dynamic equations (\[eq:cRdot\]), (\[eq:cIdot\]), (\[eq:cOdot\]), and (\[eq:Ldot\]). Parameter values are $J_R = 26 \times 10^{-5} \,\upmu$m$^{-1}$s$^{-1}$, $J = 55 \times 10^{-5}\,\upmu$m$^{-1}$s$^{-1}$, $\kappa = 2 \times 10^{-2} \,\upmu$m$^{-1}$, $\kappa_R = 5 \times 10^{-3} \,\upmu$m$^{-1}$, $\gamma = 10^{-2}\,$s$^{-1}$, $v_g = 0.1 \,\,\upmu$m$^2$s$^{-1}$, $v_s = 0.5 \,\upmu$m$^2$s$^{-1}$ and $n = 4$. b) Dependence of the mean length on $J_R$ for different values of the Hill coefficient $n$. c) Dependence of the mean length on $J_0$ for different values of the coupling constant $J_R$ and $J_I = J_0$. The other parameters are as in (a), $L_{\text{min}}$ is calculated from Eq. with $J_I = 55 \times 10^{-5} \,\upmu$m$^{-1}$s$^{-1}$.](FolzetalFig4.pdf){width="47.00000%"} We have checked that the solutions are stable against fluctuations of the delay time up to 10%, see S.M. We also found that lossy transport of the signals along the axon does not qualitatively change the system’s behavior, as we show in the S.M. From a more general point of view, our system achieves length regulation through an adaptive delay, which is determined by the axon length. Adaptive delays have also been proposed as a mechanism to retrieve information from chaotic neural networks [@Crook:2003ci]. It is also interesting to compare our mechanism to Laughlin’s proposal of regulating lengths by resonant chemical waves [@Laughlin:2015hm], where he exploits a formal analogy of excitable systems with an effective amplifying and saturable medium, like in lasers or electronic circuits. Even though a mapping from the present model to reaction-diffusion equations is not evident, let us exploit the similarity of the term of length growth and shrinkage in Eq. (\[eq:Ldot\]) with gain and loss terms of a laser. As the system tunes its length, it eventually reaches a state in which the gains on average equal the losses. This goes hand in hand with the selection of a specific frequency and phase-locking of the different oscillating signals, which is akin to a resonance in an amplifying medium. For the parameters chosen in Fig. \[fig:exampleLengthRegulation\]a, the average axon length would be 125 $\upmu$m and the oscillation amplitude below 1 $\upmu$m. Such small oscillations would likely be masked by fluctuations in a real axon. It would now be interesting to link in molecular detail the regulation of growth cone extension and axon contraction. In particular, the regulation of axon contractility most likely requires a description that explicitly accounts for the spatial degree of freedom along the axon. L.W. and K.K. acknowledge support by DFG through SFB 1027. [99]{} natexlab\#1[\#1]{}bibnamefont \#1[\#1]{}bibfnamefont \#1[\#1]{}citenamefont \#1[\#1]{}url \#1[`#1`]{}urlprefix\[2\][\#2]{} \[2\]\[\][[\#2](#2)]{} , , , , , , ****, (). , , , , , ****, (). , , , ****, (). , , , ****, (). , ****, (). , , , ****, (). , , , , , ****, (). , , , , , ****, (). , , , , ****, (). , , , ****, (). , , , , , , , , , ****, (). , , , ****, (). , , , ****, (). , ****, (). , ****, (). , ****, (). , , , , , , , , , , , ****, (). , ****, (). , , , ****, (). , , , , , , , ****, (). , , , , , , , , , , , ****, (). , ****, (). , ****, (). , **** (). , ****, (). , , , , , , ****, (). , , , ****, (). , ****, (). , ** (). , , , , , , , , , , , ****, (). , , , , , ****, (). , , , ****, (). , , , ****, (). [^1]: These results also hold if the value of $J_I$ is fixed while changing $J_0$. | Mid | [
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Abstract Background: The present study aimed to evaluate the operators’ mental workload (MW) of cement, city traffic control and power plant control centers using subjective and objective measures during system vital parameters monitoring. Methods: This cross-sectional study was conducted from June 2014 to February 2015 at the cement, city traffic control and power plant control centers. Electrocardiography and electroencephalography data were recorded from forty males during performing their daily working in resting, low mental workload (LMW), high mental workload (HMW) and recovery conditions (each block 5 minutes). The NASA-Task Load Index (TLX) was used to evaluate the subjective workload of the operators. Conclusion: The results suggested that when operators’ mental demands especially in traffic control and power plant tasks increased, their mental fatigue and stress level increased and their mental health deteriorated. Therefore, it may be necessary to implement an ergonomic program or administrative control to manage mental probably health in these control centers.Furthermore, by evaluating MW, the control center director can organize the human resources for each MW condition to sustain the appropriate performance as well as improve system functions. | Mid | [
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public class Main { public static void main(Main[] args) { if(args != null && args.length > 0) { assert(args[0] == null); // allowed to fail } } } | Low | [
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If this is your first visit, be sure to check out the FAQ by clicking the link above. You may have to register before you can post: click the register link above to proceed. To start viewing messages, select the forum that you want to visit from the selection below. OpenSource wont be 100% OpenSource anymore! Opinion Red Hat and Mandrake are cutting support for older versions of their Linux distributions... The results will be a security nightmare for the Internet, says Jon Lasser. Open source opponents have for years warned, "You get what you pay for." Now some Linux distributors are planning to make good on that threat. Red Hat and Mandrake's recently-announced revised support policies might spell the end of the free ride for many companies using Linux. The policies are straightforward: Red Hat will support their regular distributions for twelve months from initial release. Red Hat's venerable version 6.2 will be retired on March 31st along with version 7.0. Versions 7.1 through 8.0 will expire on December 31st. After the expiration date, security patches will be provided at Red Hat's discretion only. Mandrake's new policy is similar, though a little more confusing: Mandrake will support "desktop components" of any new distribution for twelve months, and they'll support "base" components, including the kernel and Apache, for eighteen months. Which category the other packages fall into remains to be seen. Mandrake 7.2 and 8.0's desktop components are immediately unsupported, while their base components will be supported until March 31st. Mandrake will drop support for 8.1, both desktop and base packages, as of March 31st as well. Version 9.0's end-of-life dates are September 30th and March 31st of next year. How you interpret these announcements depends on what hats you wear: I didn't know whether I should, laugh, cry, or cheer. As a systems administrator, my first reaction was definitely to cry. Vendor-provided security patches are, unfortunately, the lifeblood of distribution support. Without well-integrated and well-tested patches, maintaining a Unix server takes a lot more work: you have to track every installed package on your system and rebuild necessary subsystems whenever a patch is released. Though users of commercial Unix distributions have been doing this for years, users attracted to Linux's relative ease of use and maintenance frequently don't have the technical skills to keep up while not falling behind on other important tasks. Without these vendor-provided patches, most Linux users -- and even many professional system administrators -- will have trouble keeping their systems safe. Twelve or eighteen months is nothing in the life of a production server. In many shops it can take more than six months to certify an application for use. In such an environment the install-test-release cycle would be constant. Furthermore, servers are often hard to update: permissible downtimes may be rare, and co-located servers are even more difficult to handle. Two Weeks Notice On the bright side, at least Red Hat and Mandrake have policies that will allow me to plan, or to make other arrangements. I still have a bad taste in my mouth from the Debian 2.1 support debacle. On September 14th, 2000, the Debian project announced that, as of September 30th, support for Debian 2.1 would be dropped entirely. Two weeks notice is simply not enough time to do even minimal testing before updating a production server doing anything more complicated than serving static Web pages. Furthermore, Debian 2.2 had been released on August 14th -- only one month earlier. I know that Red Hat and Mandrake have important reasons to limit support for older operating systems: first, open-source software has an unfortunate tendency to live forever -- many users are still relying on versions of Red Hat even older than 6.2, and supporting these primordial distributions is expensive. The QA and build machines need to be supported, and developers must be diverted from more forward-looking tasks. Given that Linux distributors make little money supporting these older releases, dropping patches must seem like a no-brainer from their point of view. And to their credit, both companies have different rules for "server-class" products: Red Hat will support their Advanced Server for five years, and Mandrake's policy states that server software will be supported for "no less than twenty-four months." Red Hat and Mandrake are clearly banking on support contracts and installations of their advanced server products to generate revenue. It's not unreasonable to expect people who want commercial quality support to pay for it. But as an advocate for better computer security, I'm nearly panic-stricken over this move. In the short term, at least, this will be a big negative for practical security on the Internet. Old software doesn't go away just because it's no longer supported, and with network operating systems the consequences could be drastic. Those systems will be sitting ducks for vulnerability scanners, and the size of distributed denial-of-service networks may grow exponentially as a result. Silver Lining? After all, many users have come to rely on the auto-update mechanisms provided by vendors, such as Red Hat's up2date tool. When Red Hat's support for 7.3 goes away, tens of thousands of users will have no automated way to apply third-party security patches to the base OS. As an open-source advocate, I must say this problem is also an opportunity. We have a large base of commonly used open source applications, and we now have to develop support mechanisms that do not rely on a single commercial vendor. Although up2date is closely tied to Red Hat's proprietary Red Hat Network support offering, an up2date server clone is under development. Its feature set is rather limited at present, but Red Hat's new support policy will undoubtedly drive many users to run their own patch servers. Another tool that could be used is Connectiva's port of Debian's apt package management front-end to Red Hat's RPM format. Running an apt repository is not difficult and provides an excellent mechanism for continued security updates. All that is necessary is continued community support for the orphaned distributions, in the form of well-managed projects that follow security updates for core OS components, and then build and extensively test new packages on the target platform. If you think that this sounds like an opportunity for third-party support vendors, you're right about that, too. I suspect that Tummy.com's KRUD distribution which provides monthly updates to a Red Hat-based system, will gain quite a number of customers. I know of at least one other vendor who is considering a Red Hat support offering including packages for older Red Hat versions. Open source proponents have long claimed that our community can provide better support than any commercial vendor can. Now we'll have to prove it. it was bound to happen, to major Linux distributors like RedHat and Mandrake I'm pretty sure the community will pick up where the companies leave off. I've found that often the community is more helpful, because they don't worry about feasibity of supporting somthing, they just do what needs to be done. I've found very little support for winmodems from actual companies, most of the drivers I've found were written by groups or individuals. But your right, we will definately see how far the community can go as far as support and such will go. If a particular distribution is not supporting a certian distro anymore just means they are evolving. While I agree the support life of a distro is shorter than an MS or other OS, I have to disagree this means it not "open source" anymore. Just because a company does not support a distro, does not change the licensing terms in which the software can be used and implimented has changed. As the article said, it just means more work for administrators and users to go and find patches for packages, kernel upgrades, etc. However, there are programs out there to check for updates and the like if you are really gung-ho in keeping your current distro and not going to the lastest and "greatest" thing. Take Red Hat 8.0. A lot of people do not like Red Hat 8.0 and prefer 7.3. it does not mean it cannot be upgraded It just means Red Hat themselves will want nothing to do with it to support newer versions. Further, like Syini666 said, there is a huge community base and if you need help and support for unsupported distro, there is plenty of people willing to help. I'm going with Syini666 on this one, I find that redhat.com's web site is worthless compared to doing a google on a command or come here. Also the MAN pages help out a lot. Heck you don't really need to even use the destributor for help. :-\ To be God is to be Root, if someone is erking you just type: rm -d /home/heathen I have to agree with Wickdgin this doesn't change the Open Source agreement. Truly the Linux community will be a better source of support than the companies. Time will shed better light upon this subject and know how will better serve the community as a whole. I would prefer to write my own kernel anyway to test out my ideas | Mid | [
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803 F.2d 1181Unpublished Disposition NOTICE: Fourth Circuit I.O.P. 36.6 states that citation of unpublished dispositions is disfavored except for establishing res judicata, estoppel, or the law of the case and requires service of copies of cited unpublished dispositions of the Fourth Circuit.UNITED STATES of America, Appellee,v.James Preston SCIPIO, Appellant.UNITED STATES of America, Appellee,v.James Preston SCIPIO, Appellant. Nos. 85-5225(L), 85-5226. United States Court of Appeals, Fourth Circuit. Submitted Sept. 26, 1986.Decided Oct. 24, 1986. James Preston Scipio, appellant pro se. Catherine C. Blake, United States Attorney, Peter D. Ward, Assistant United States Attorney, for appellee. D.Md. AFFIRMED. Before RUSSELL, SPROUSE and CHAPMAN, Circuit Judges. PER CURIAM: 1 James Preston Scipio appeals his conviction on two indictments charging a total of two counts of mail fraud and five counts of wire fraud. Scipio pleaded not guilty on all counts of the two indictments and was tried by juries in separate trials with different co-defendants. Scipio was found guilty on all counts, and a sentence of six years was imposed in each case; the two sentences are to run concurrently, with concurrent five year probation terms following release. This appeal followed. 2 By order of 1 April 1986 this Court denied Scipio's motions for leave to proceed in forma pauperis and appointment of new counsel; we granted Scipio's trial counsel's motion to withdraw appearance at the same time. Scipio has failed to provide this Court with a transcript; he has therefore waived any claim concerning the sufficiency of the evidence at trial. United States v. Tedder, 787 F.2d 540, 541 n. 2 (10th Cir.1986). Though we have examined the exhibits and motions included in the record, it is impossible to review either the sufficiency of the evidence or the adequacy of its presentation without a transcript. 3 Scipio seeks to raise an issue of ineffective assistance of counsel in this direct appeal. This claim would more appropriately be directed to the district court in 28 U.S.C. Sec. 2255 proceedings. United States v. Grandison, 783 F.2d 1152, 1156 (4th Cir.1986). 4 Scipio also claims that "there exists a vast disparity in sentencing" because he received a more harsh sentence than his co-defendants in either trial. Extensive proportionality analysis of sentence is required only in a case involving a life sentence without parole. United States v. Rhodes, 779 F.2d 1019, 1028 (4th Cir.1985), cert. denied, --- U.S. ---, 54 U.S.L.W. 3823 (June 16, 1986). Reviewing courts "should grant substantial deference to the broad authority that legislatures necessarily possess in determining the types and limits of punishments for crimes, as well as to the discretion that trial courts possess in sentencing convicted criminals." Id. (quoting United States v. Solem, 463 U.S. 277, 290 (1983)). We therefore uphold Scipio's sentences as within the discretion of the district court and as appropriate within the limits set by Congress. 5 The judgments of conviction and sentences imposed on each count are affirmed. We dispense with oral argument because the dispositive issues recently have been decided authoritatively. 6 AFFIRMED. | Low | [
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PITTSBURGH (KDKA) — Surveillance video of a confrontation at the North Versailles Walmart has been released, showing a woman pulling a gun and opening fire. The incident happened on July 5 inside the store. The suspect, 22-year-old Rojanai Alston, was in court Thursday where a charge of attempted homicide was dropped. However, she is still facing aggravated assault charges in the case. RELATED STORIES: The video shows Alston and a group of other people get into a brawl. Alston’s attorney says his client was shopping when she was approached by two women who wanted to attack her. “I think the evidence will show she is not guilty of anything,” attorney Kenneth Haber said. “She had a gun and had to use it, but it was not criminal.” The video was shown at the hearing. WATCH THE VIDEO HERE: Harber said there was a verbal exchange, and Alston walked away. “As the video shows, she was attacked from behind by both women,” Harber said. “She was cold-cocked. My client was punched repeatedly by both, and they attempted to drag her to the ground. She did have a firearm, she had it in her purse. She purchased it legally and had a license to carry it.” The alleged attackers did not appear at the preliminary hearing, and the Commonwealth brought one detective as a witness. Alston is out on bond and will be arraigned Sept. 4. | Low | [
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The Weekly Burst Report is a report published every Sunday meant to centralize and outline the important Burst information of the week. Development Core development statistics since last week: – Files modified: 24 – New insertions (+): 983 – New deletions (-): 606 When the PoC Consortium released the BRS 2.0.0 core version last week, it was made clear right away that there could be a few remaining bugs due to the magnitude of the code refactoring. The developers worked hard this week to eliminate most reported issues – “we would like to thank all the early adopters who supported development by testing 2.0.0”, states PoC Consortium member rico666. The BRS 2.0.1 core version is now out, and it offers better performance, stability and security compared to any release so far. This version is thought for a broader audience, but still not as backend for pools – pool operators should wait for the next version before updating. The PoC Consortium confirmed that Qbundle v2.0 is going to be released this Monday. It will be based on BRS 2.0.1 and it will allow the majority of users to upgrade to the latest version with one click. We can also expect a BRS 2.0.2 core version before the first fork. A small bonus: the PoC Consortium released a Discord bot that automatically reports forged blocks. The bigger picture – a PoC Consortium developer’s interesting insight on the future Burst Dymaxion use cases: Websites BurstJack is still making progress on the Automated Transactions listing website. All smart contracts are now imported from the Burst blockchain and searchable. As you may already know, our Burst wikipedia article is about the be delisted. One of the main concerns there is that burst doesn’t have enough 3rd party websites writing about it. Hence, please read this post & comments if you would like to help with marketing in a meaningful way. And speaking of marketing, here is another easy trick to promote Burst. Other LinusTechTips mentioned Burst once again in one of their videos. And it seems like they are going to release a dedicated video on Burst mining soon. Want to see an inspiring display of community engagement? Reddit user u/pskrzyni81 decided to represent Burst at the Blockchain & Cryptocurrency – BNFT Panel in Long Beach Convention CA last weekend. He handed out Burst flyers, and even ended up joining a booth! This is of course a great example to follow – we would love to see Burst being represented by community members more often in this kind of events. Have you ever wished you could have a truly unique and memorable Burst Address? With adrownedcoast’s Burst Vanity Address Generator written in Python, you can generate custom Burst addresses using the 4 leading characters of the address after “BURST”. Check it out on GitHub. MinerGate published a great article on Burst’s consensus protocol: Why Proof-of-Capacity could be the future of cryptocurrency. There will be a new community meme competition starting from April 1st. Get ready! The first episode of the Harvey Harddrive community comic series is out: the origin of it all. Conclusion With the release of BRS 2.0.1 (and soon Qbundle 2.0), the refactored wallet is effectively going to be the foundation of the future Burst – we will need the community to upgrade in a timely manner in order for the transition to BRS 2.2.0 (the first fork) to be as smooth as possible. As always, stay informed and proactive. Thank you and see you next week. Tom Créance (@Gadrah) Want your Burst-related project to appear in the Weekly Burst Report? Contact me and I can mention it next week. Also published on Medium. | Mid | [
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This image was removed due to legal reasons. Ruben Zamora got the tattoos when he was 16. There’s the headdress on his back. His mom's last name stretching across his shoulders. The laughing and smiling faces inked into his bicep. At the time, he was hanging around with a new group of guys; he was just trying to be cool. He liked how they looked, and thought, why not. But now, Zamora’s tattoos have torn his family apart. Even though he’s lived in New York since he was eight, is married to a U.S. citizen, and has two young children born here, he hasn’t been allowed to return home from Mexico for more than a year. Getting tattoos “was one of my biggest mistakes in my life,” he told me in a phone call from a suburb of Mexico City, where he’s been living since he was separated from his family in July 2014 while trying to get legal status. The State Department claims the tattoos are evidence that he’s a member of a criminal organization—and he’s not the only immigrant to be denied a visa for his ink. But Zamora, 29, says that he's never been a gangster and the tattoos alone shouldn’t be enough to bar him from the country where he’s lived most of his life. “My only crime was to get these tattoos,” he said. Last year, hoping to get a job with benefits and give his family a better life, Zamora decided to pursue acquiring legal status. The fact that he was married to a citizen and had lived and worked in the U.S. for decades made him a prime candidate, and he was told he just had to go back to Mexico for two weeks while he submitted his application. Things took a turn when Zamora went in for the medical exam at the American consulate in Juarez and a nurse told him to take his clothes off. “She saw my tattoos and she started writing,” Zamora said. In the interview, Zamora thought he’d be asked about his family, his job, where he lived. But it seemed like all the officials were interested in were the tattoos. And then he got the denial letter, letting him know that he wouldn’t be going back to New York. Last week, the State Department supported the consulate’s decision in an email to Zamora’s lawyers. “It is a probability, supported by the facts, that the alien is a member of an organized criminal entity,” the email read. “I just thought it was going to be coming here, doing the interview and going back home,” he said. “If I ever thought that I would have been having problems with my tattoos, I would never have risked coming back here.” This image was removed due to legal reasons. The separation is taking a toll on his family. In an interview in her fifth-floor walk-up apartment in the Bronx, Zamora’s wife Vanessa Ruiz said she had put off medical bills and almost lost her housing after her husband, the breadwinner, went away. "They broke my heart" when Zamora was denied a visa, Ruiz said. Their two sons, Ryan, 10, and Aiden, 3, are struggling without their dad. "They ask me every day, when is papa going to come home, and I don't know how to explain it to them," she said. In February, they went and visited Zamora in Mexico. They stayed in the state of Puebla, going out every night to a festival, and the boys’ faces would light up. “It felt like we were a family again,” Ruiz said. It was hard for Zamora, especially to see how much he had missed, especially with his three-year-old. “You have that image of your kid when you left him and you expect to see him the same way,” Zamora said. “He’s grown fast.” Now, they communicate over FaceTime. "Te quiero mucho," Ruiz told him, sobbing, as she hung up a call on Wednesday night. Living in Mexico with his aunt, Zamora said the tattoos even make it hard to get a job there. He’s working part-time at a bakery, making a few dollars a day. A State Department spokesperson said that they could not comment on individual cases, but said that “a consular officer considers all available evidence regarding potential gang affiliation during the visa process.” This image was removed due to legal reasons. The tattoo that looks the most suspicious is the two faces on his left arm, one laughing and one crying. It’s associated with the Sureños, a Mexican-American gang. Zamora says the guys he was hanging around with as a teenager suggested it, and he stopped seeing them soon after. Barely a year after he got the tattoos, he started a job as a busboy at a bustling Jamaican restaurant in the West Village and met Vanessa. He held the same job for 11 years. “How would he even have time to be in a gang?” Ruiz asked. He would work double shifts, and spend his weekends with his family. One of his co-workers, Gabriel Zapata, said the idea of Zamora being in a gang was ridiculous. "He was always calm, always a good person," Zapata said. He thinks the denial has to do with prejudice against Latin American men with tattoos. "I'm standing here, not a problem for anyone," Zapata said. He pulled up his pant leg, showing a colorful design snaking up his ankle. "And now I'm a danger to society." Zamora isn’t the first person to get denied a visa because of his tattoos. Several other Mexican men have had the same problem. One Colorado man, Hector Villalobos, sued the State Department in 2012 over what he said was an unjust decision. Attorney Patrick Taurel, who represented Villalobos, said the lawsuit was thrown out in court, and the State Department's internal appeal was a dead end. “In our case, they were so sloppy they didn’t even get my client’s name right in their decision,” he told me. Villalobos has been living in Mexico ever since. A Supreme Court decision handed down last year seemed to close the courthouse door on any chance of judicial review, backing up the notion of “consular non-reviewability,” that as long as State Department has some bona fide reason for denying a visa, a denial can’t be appealed to courts. The idea is that if even a fraction of the millions of people who apply for a U.S. visa each year decided to appeal a denial, the courts could be overwhelmed. The only option, it seems, is for Zamora and his family to convince the State Department to reconsider by giving them as much evidence as possible that he’s not a gang member. Audrey Carr, his lawyer, said an expert in Mexican gangs has written an affidavit saying Zamora is not a gang member. They’re also hoping to put public pressure on the agency. “You can’t deny someone a visa solely because of his tattoos,” Congressman José Serrano, who represents Ruiz, said in a statement. “I believe the process needs to be examined to ensure it is fair and that applicants’ rights are protected, especially in cases like Mr. Zamora’s where you have someone with deep roots and family ties in the United States.” Of course, Zamora is also thinking about having the tattoos removed. He’s made plans, he said, to get rid of at least the one associated with the Sureños. But he knows that even if he can take the ink out of his skin, the State Department still has the photos on record. All he can do is hope for a change of heart. “They shouldn’t just judge me because of the appearance of my tattoos,” he said. “I just want to see my family again.” Casey Tolan is a National News Reporter for Fusion based in New York City. | Low | [
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/* * Copyright (c) 2018, APT Group, School of Computer Science, * The University of Manchester. All rights reserved. * DO NOT ALTER OR REMOVE COPYRIGHT NOTICES OR THIS FILE HEADER. * * This code is free software; you can redistribute it and/or modify it * under the terms of the GNU General Public License version 2 only, as * published by the Free Software Foundation. * * This code is distributed in the hope that it will be useful, but WITHOUT * ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or * FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License * version 2 for more details (a copy is included in the LICENSE file that * accompanied this code). * * You should have received a copy of the GNU General Public License version * 2 along with this work; if not, write to the Free Software Foundation, * Inc., 51 Franklin St, Fifth Floor, Boston, MA 02110-1301 USA. */ #include <stdio.h> #include <stdlib.h> #include <unistd.h> /* * Writes the contents of the codebuffer to stdout in binary format. * The output can be disassembled using e.g. objdump. */ static void print_code_buffer(); static void c_entry(); int main (int c, char **v) { c_entry(); /* initialise code array */ print_code_buffer(); /* print code array in binary */ exit(0); } #include "./codebuffer.c" } void print_code_buffer() { int i; fprintf(stderr, "Bytes: %lu\n", sizeof(code)/sizeof(char)); for (i = 0; i < (sizeof(code)/sizeof(char)); i+=4) { write(fileno(stdout), &code[i], 4); } } | Mid | [
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In theory, Ocellus could´ve just shape-shifted to make it look like she was wearing her uniform. Also, I love how Yona was basically just there to get ponies to stomp, and to support the pony pyramid. She isn´t the most agile, so it was the perfect job for her. Most other coaches would´ve probably kicked her out because she sent the rest of the squad to hospital. Anyway, how come Ocellus has a light blue exo-skeleton while Smolder doesn´t have scales? Not that I´m complaining, it´s just, well, it kinda bugs me. No pun intended (or is it?). | Mid | [
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Cam Ellis-Yolmen’s outstanding SANFL season has been rewarded with a place in the League’s 2016 Team of the Year. Ellis-Yolmen, who was Adelaide’s leading vote-getter at the SANFL’s Magarey Medal count, secured a place on the interchange in this year’s team. It’s deserved recognition for the hard-nosed midfielder. He finished the home and away season as the No.1 player in the SANFL for contested possessions (235), was third in clearances (110) and sixth for total disposals (459). Ellis-Yolmen was the only Crow to feature in the side. Teammates Harrison Wigg, Jonathon Beech and Reilly O’Brien were named in the initial squad but were overlooked in the final 21-man team. Minor premiers Woodville-West Torrens dominated selection with six players in the side, including four in the backline alone. Sturt was the next-best represented team with five players featured. First-year Double Blues coach Marty Mattner was named coach of the year. Finalists Central District and South Adelaide both had three players included, while Norwood, Glenelg and Adelaide all had one player each. The team does not feature any player from bottom-two clubs West Adelaide and North Adelaide. Magarey Medallist Zane Kirkwood was named captain with former Crow Luke Thompson vice-captain. The selection committee comprises of the SANFL’s Adam Kelly, Tom Hurley and Zac Milbank, Channel 7’s Mark Soderstrom and Advertiser Chief SANFL Writer Warren Partland. SANFL Team of the Year – Club by club Adelaide Cam Ellis-Yolmen Central District Travis Schiller Justin Hoskin Chris Jansen Glenelg Josh Scott Norwood Sam Baulderstone Port Adelaide Kane Mitchell South Adelaide Brett Eddy Tom Fields Brede Seccull Sturt Mark Evans Kory Beard Zane Kirkwood Fraser Evans James Battersby Woodville-West Torrens Nick O’Brien Jarred Allmond Matthew Goldsworthy Patrick Giuffreda Luke Thompson Jared Petrenko Coach Martin Mattner (Sturt) | High | [
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Q: Reducing the similar like queries I have these four similar like queries: $products=Product::orderBy('views','desc')->with('category')->get(); //----1 $mostviews=Product::orderBy('views','desc')->limit(10)->get(); //----2 $show=Product::orderBy('views','desc')->with('category') ->with('user') ->with('productbrand.brand') ->first(); //----3 $shows=Product::orderBy('views','desc')->limit(20) ->with('category') ->with('user') ->with('productbrand.brand') ->get(); //----4 but for different purposes. to get all products with categories. to get 10 products to get one product with categories, users, and brand to get 20 products with categories, users, and brand How can the queries be reduced? A: You don't need to create all those variables. Just do this: $products = Product::orderBy('views','desc') ->with('category', 'user', 'productbrand.brand') ->get(); After you got the data, use this variable. But I would also recommend you to not use take() method if you have product descriptions and/or specifications in DB. Because if you'll do this, it can easily take all memory. The thing is each take() will create new collection. You can use $products without creating new collections or variables: // Show: {{ $products->first()->id }} // Most views: @foreach ($products as $product) @if ($loop->iteration > 10) @break @endif {{ $product->something }} @endforeach // Shows: @foreach ($products as $product) @if ($loop->iteration > 20) @break @endif {{ $product->something }} @endforeach | Mid | [
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#ifndef RELU_H #define RELU_H #include "util/gnn_macros.h" #include "nn/factor.h" #include "nn/variable.h" #include <memory> namespace gnn { template<typename Dtype> void ReLUAct(DTensor<CPU, Dtype>& in, DTensor<CPU, Dtype>& out); template<typename Dtype> void ReLUAct(DTensor<GPU, Dtype>& in, DTensor<GPU, Dtype>& out); template<typename Dtype> void ReLUDeriv(DTensor<CPU, Dtype>& dst, DTensor<CPU, Dtype>& cur_output, DTensor<CPU, Dtype>& cur_grad); template<typename Dtype> void ReLUDeriv(DTensor<GPU, Dtype>& dst, DTensor<GPU, Dtype>& cur_output, DTensor<GPU, Dtype>& cur_grad); /** * @brief the rectifer linear unit operator * * @tparam mode { CPU/GPU } * @tparam Dtype { float/double } */ template<typename mode, typename Dtype> class ReLU : public Factor { public: static std::string StrType() { return "ReLU"; } using OutType = std::shared_ptr< DTensorVar<mode, Dtype> >; /** * @brief Creates an out variable. * * @return return a tensor with same shape/type as input tensor */ OutType CreateOutVar() { auto out_name = this->name + ":out_0"; return std::make_shared< DTensorVar<mode, Dtype> >(out_name); } /** * @brief constructor * * @param[in] _name The name * @param[in] _properr whether propagate error */ ReLU(std::string _name, PropErr _properr = PropErr::T); virtual void Forward(std::vector< std::shared_ptr<Variable> >& operands, std::vector< std::shared_ptr<Variable> >& outputs, Phase phase) override; virtual void Backward(std::vector< std::shared_ptr<Variable> >& operands, std::vector< bool >& isConst, std::vector< std::shared_ptr<Variable> >& outputs) override; }; } #endif | Mid | [
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Okay, I know I haven’t been posting in a while! YIKES! But I got a couple of big ones coming up here! So here it comes… The first event I went to I did not wear my sash or crown, why? I did not want to shine out and have all the attention on me, when it wasn’t my event, and it was for a sad but reasonable cause! The event was made to fund-raise money for medications in Ukraine. A young lady named Halyna was hosting and organizing the event, she planned to buy medicine and fly to Ukraine to give it to those in need. The minimum you could put in to join the event (which included a coupon to the restaurant where it was being held, for a free appetizer if you buy a main course! YUM!) was $20 I know there is a lot of people in need of help there, and people who are close to me that have families there which are struggling, so why not put in $50, right? Anyway, I went with my boyfriend and we decided not to put those coupons to waste and have dinner there! The restaurant is called Ganzi, it is Italian… And the whole menu is IN ITALIAN! So we both had to ask the waiter what every single item on the menu was… That was not so exciting. But the food, oh my goodness the food was heaven sent! The portions were not so big, but the way it was prepared, served, and how it tasted was perfection! I have never been to Italy (although I REALLY REALLY want to!) but I’m quite sure that that is what the food there would taste like! Ganzi is not sponsoring me, and I am not doing this “promotion” because I have made a deal, I am saying this straight from my heart! All in all that was a great night! Many people came out to support Ukraine, and give money for a good cause, plus the food was definitely worth the 1 and a half hour long drive. | Mid | [
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This week’s Switch eShop charts are as follows: Software 1. Minecraft: Nintendo Switch Edition 2. Ultra Street Fighter II 3. Shovel Knight: Treasure Trove 4. Thumper 5. Mario Kart 8 Deluxe 6. NBA Playgrounds 7. Has-Been Heroes 8. Disgaea 5 Complete 9. Zelda: Breath of the Wild 10. Snipperclips 11. Puyo Puyo Tetris 12. Kamiko 13. Wonder Boy: The Dragon’s Trap 14. The Jackbox Party 3 15. The Binding of Isaac: Afterbirth+ 16. 1-2-Switch 17. I Am Setsuna 18. Blaster Master Zero 19. ACA NeoGeo Metal Slug 20. FAST RMX Share this: Twitter Facebook Reddit Tumblr Pinterest More Email Print LinkedIn Google Pocket | Mid | [
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Heterologous expression of the cytochrome P450cam hydroxylase operon and the repressor gene of Pseudomonas putida in Escherichia coli. The cytochrome P450cam hydroxylase operon (camDCAB) of Pseudomonas putida is negatively regulated by a repressor, CamR, which also represses its own gene. The expression in P. putida of both camR and camDCAB is derepressed in the presence of D-camphor. We examined the expression in Escherichia coli of camR and camDCAB by monitoring the enzyme activity of the camD gene product. In the presence or absence of D-camphor in the cell culture, the expression in E. coli of camD was significant and constitutive, suggesting no expression of camR. This lack of expression was confirmed by monitoring the beta-galactosidase activity of camR-lacZ translational fusions. However, S1 nuclease mapping revealed that synthesis of camR mRNA in E. coli was significant and constitutive, as observed in the case of camDCAB mRNA. Thus, it is likely that the expression of camR in E. coli is limited at the translational level. | Mid | [
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Abstract The existence of street children in our social structure is still underestimated and being ignored by some people, it has happened since years ago, and it seems not getting better until right now. One of the reasons is because of the differences between their culture and normative culture that normally prevails in our community. The street children, with their limited, threaten, suffering and despair condition, are trying to survive from economic condition exploitations that usually happen in the street everyday. Conceptually, The Streets Children can be categorized as a child worker but practically; they are actually a special group that have different character with the other child workers. Since their life tough and challenging, they end up to making their own community with own type of family's normative, own way of life and own way of communication. The impact then is formed such a gap between them and common community and finally formed what we call " Social Discrimination". The most important thing to consider in studying about their limitation is that need more specific approach that directly involve the investigator into their real life. The best approach that can be used is " the sociological legal approach " with interpretative understanding method. In Indonesia, it seems that not every policy in legal protection toward the street children that applied now a days based on deep problem understanding. Legal protection policies on street children that have implemented tend not to be building permanently if we cannot say contradiction. This is because the law who must protect the children's basic rights precisely wrestle with their own problem. The World Convention on the Right of the Child. 1989, that have been ratified with Keopres Nomor 36 Tahun 1990, in the implementation's found some problems and troubles too in adopting into social, economic and cultural condition of Indonesian Law. This condition become worst because of the lack of information and knowledge about children's rights that most parents have, and also because there aren't any good institutions that concern in protecting children optimally which usually can't attempt very hard with some reasons. The other thing is we also have very little professional and skill people which are capable to give' some solutions that use actually need badly to overcome the complex problem, and also because we have less cooperation with cross-sect oral and international link. The government has not been able to catch the sign that law enforcement matter as a social process is actually opened and involve the environment, where accepting any limitation on the process. More over when law is faced to phenomenon of poverty in the middle of economic development in urban area only, which emphasise more about the growth, without considering the aspect of even distribution and mass empowering, including the street children. In other word, law is not the only one activator of development process. There are many other factors that determine the success of development it self, such as economic, politic, social, cultural and religion. Keberadaan anak—anak dalam tatanan masyarakat sampai dengan saat ini oleh sebagian orang masih dianggap remeh dan tersisihkan. Hal ini sudah berlaku sejak bertahun-tahun yang lalu dan nampaknya tidak berangsur baik hingga kini. Salah satu sebabnya adalah perbed.aan antara budaya mereka dengan budaya normatif yang lazim dikomunitas lcita. Anak jalanan dengan kondisi mereka yang terbata.s, terancam, menderita dan putus asa berusaha untuk bertahan dari kondisi ekonomi yang mengeksploitasi yang bisanya terjadi di jalanan setiap hari. Secara konseptual anak jalanan adalah salah satu kategori pekerja anak, tetapi secara praktis anak jalanan dapat dianggap sebagai suatu kelompok- khusus yang berbeda karakter dengan pekerja anak lainnya. Karena kehidupan mereka yang keras dan menantang, pada akhirnya mereka membentuk komunitas mereka sendiri, dengan tipe norma keluarga sendiri, cara hidup sendiri, cara berkomunikasi sendiri. Akibatnya kemudian terbentuk semacam jurang antara mereka dengan komunitas masyarakat pada umunmya dan akhimya membentuk apa yang disebut "Diskriminasi Sosial". Hal terpenting yang hams diperhatikan untuk mengkaji mengenai keterbatasan mereka memerlukan pendekatan yang lebih spesifik yang melibatkan secara langsung peneliti ke dalam kehidupan nyata mereka. Pendekatan terbaik yang dapat dipergunakan adalah pendekatan sosiologis hukum dengan metode pengertian pemahaman secara mendalam. Di Indonesia, sepertinya tidak setiap kebijakan perlindungan hukum terhadap anak jalanan yang diterapkan selama ini didasari oleh pemahaman masalah secara mendalam. Kebijakan perlindungan hukum terhadap anak jalanan yang diterapkan selama ini cenderung bersifat tambal sulam saja, kalau tidak ingin dikatakan kontradiksi. Hal ini dikarenakan hokum yang seharusnya melindungi hak-hak dasar anak jalanan justru bergelut dengan masalahnya sendiri. Konvensi arlizk--Hak Anak Dunia 1989 yang telah diratifikasi dengan Keppres Nomor 36 Tahun 1990 dalam pengejawantahannya sedikit-banyak mengalami kendala dalam hal keserasiannya dengan kondisi sosial, ekonomi, budaya masyarakat hukum Indonesia Hal di atas diperparah dengan kurangnya pengetahuan masyarakat terutama orang tua terhadap hak-hak anak serta beim adanya lembaga perlindungan anak yang secara optimal menangani masalah anak jalanan. Kurangnya tenaga terdidik dan profesional dalam menangani masalah anak jalanan. Kurangnya tenaga terdidik dan profesional dalam menangani masalah anak jalanan serta kerja sama lintas sektoral dan internasional kurang terjalin dengan balk. Pemerintah belum bisa mencermati bahwasanya masalah penegakkan hukum sebagai suatu proses sosial adalah bersifat terbuka dan melibatkan lingkungannya, di mana menerima batasan-batasan dalam bekerjanya Apalagi bila hukum dihadapkan pada fenomena timbulnya kemiskinan di tengah pembanguan ekonomi perkotaan yang hanya menekankan pada tingkat pertumbuhan semata tanpa mempertimbangkan aspek-aspek pemerataan dan pemberdayaan rakyat kecil termasuk di dalamnya anak jalanan. Dengan lain perkataan, hukum bukanlah merupakan satu-satunya penggerak proses pembangunan. Masih banyak factor-faldor lain yang menentukan suksesnya pembangunan itu sendiri seperti ekonomi, politik, sosial, budaya dan agama. | Mid | [
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This blog contains a series of movie segments to be used to brainstorm, warm up, follow up, and activate schemata, preparing the students for the topic that will be discussed in class. Here you will find the segments, the lesson plans, and varied topics to foster conversation. You may use the activities for a full two-hour class or they can be used separately to brainstorm or wrap up the topic, focusing on conversation, vocabulary and listening comprehension. Friday, August 29, 2014 We have been having a lot of news about Wikileaks on TV and it is hard to understand what they do, especially if you are not much into this kind of topic. However, it is an interesting and important issue, which can generate a great deal of conversation. It is a very current topic. I recommend it for adults only. I. Read the text about Wikileaks below. Then retell it to a friend, using your own words. WikiLeaks is an international non-profit online organisation which publishes secret information and classified media from anonymous sourcesThe group has released a number of significant documents which have become front-page news items. According to the WikiLeaks website, its goal is to bring important news and information to the public.Another of the organisation's goals is to ensure that journalists are not jailed for emailing sensitive or classified documents. The online "drop box" is described by the WikiLeaks website as "an innovative, secure and anonymous way for sources to leak information to WikiLeaks journalists". Because of the sensitive nature of most of the information available on Wikileaks, authenticity is not just assumed. The Wikileaks community carefully vets all submissions, making absolutely sure that the innocent are protected and that the information is both secure and authentic. Why is Wikileaks so important?Wikileaks aims at being a safe place for airing documentation of corporate or governmental misdeeds. It is a safe haven for anyone, anywhere in the world, to submit sensitive information that can then beread by the public, with the ultimate aims being transparency and justice through public communication. II. Divide the class into three groups. Group 1 reads THE GOOD, Group 2 reads THE BAD, and Group 3 reads THE UGLY. THE GOOD: Complete transparency will not work in the industrial world but there is something to say for it in government. When government is dealing with its citizens, complete transparency ought to be the rule. Indeed, too much secrecy goes on in government regarding its dealings with citizens; otherwise, why would we need a Freedom of Information Act and be required to use it all the time in order to squeeze a little information out of the government? Unfortunately, this is not the secrecy that WikiLeaks exposed. THE BAD: When you are dealing with opponents, it is certainly not in your interest to expose your strategies, your tactics or your private thoughts. Private industry understands this completely and its secrecy works to great advantage all the time. Take Apple as an example. Its product development secrecy makes for huge product launch successes. And if they didn’t do that? Their success would be diminished. In government, the same is true of opponents. Face it, the world is not made up of angels. There are evil people and even just plain people who want to protect their self-interest. To win against evil people or evil governments requires not sharing your strategies or tactics. When WikiLeaks shares all the inner thoughts, strategies and tactics with the world, the US negotiating position is severely weakened. The other parties have their secrets, but we have lost ours. THE UGLY: If transparency were the rule in, say, State Department interactions, then people would have interacted differently. But State Department people felt that they could rely on secrecy to transmit their private thoughts and suggestions to their superiors and underlings. To have this trust broken is indeed ugly. With new technologies, people have to work around possible exposure. Emails are far from secure yet some people treated them as private conversations, much to their dismay when a court proceedings revealed everything. So people began using phone conversations hoping they were not tapped. Real security might only be found in one-on-one conversations in an open field. But most people using the “secure” system trusted that their conversations were private. The State Department is one area, but the Defense Department is even more extreme. One cannot win wars without secrecy. The Chinese understood that 1000’s of years ago. And having WikiLeaks expose only one side’s secrets is only a way to assure defeat for that side. Because of the intention to do just that, the efforts of Assange and his organization are indeed treason. He must be prosecuted to the maximum extent and not just on rape charges. Wednesday, August 20, 2014 This is a fascinating animated movie. The story is gripping and their assumptions witty. I hope you like it. A stereotype is “...a fixed, over generalized belief about a particular group or class of people.” (Cardwell, 1996). The use of stereotypes is a major way in which we simplify our social world; since they reduce the amount of thinking we have to do when we meet a new person. By stereotyping we infer that a person has a whole range of characteristics and abilities that we assume all members of that group have. Stereotypes lead to social categorization, which is one of the reasons for prejudice attitudes. Most stereotypes probably tend to convey a negative impression. Positive examples would include judges (the phrase “sober as a judge” would suggest this is a stereotype with a very respectable set of characteristics), overweight people (who are often seen as “jolly”) and television newsreaders (usually seen as highly dependable, respectable and impartial). Negative stereotypes seem far more common, however. I. Discuss the questions with a friend. 1. Based on the description above, how would you describe the stereotypes of the following groups of people? Americans Brazilians Muslims Baianos (for Brazilians only) Japanese Doctors Artists Models 2. If you were a person from another planet and you had to describe your stereotyped vision of human beings to the people from your planet, how would you describe us? 3. We also have a stereotyped vision of ETs. What is the image/characteristics of ETs? 4. Watch the movie segment and make a description of how humans are seen by the eyes of extra-terrestrials. Then decide which characteristics are true (or partially true) and why they have that point of view about us. MY OTHER BLOG Movie Segments to Assess Grammar Goals About Me I'm a teacher at Casa Thomas Jefferson, Brasilia, Brazil. I'm a Branch Coordinator and Teacher Trainer as well. I really like movies and seeing them with "different" eyes, trying to see how I can use them in my classroom. Recently, I have dedicated my ideas to grammar activities with movie segments because, apparently, teachers use movies for many purposes, but grammar. Working with movie segments fosters students' production and interest. I truly believe that grammar exercises should be attractive. I have just developed a new blog for movie segments to enhance topic based classes, focusing on conversation, listening comprehension and vocabulary acquisition. If you have suggestions for the blogs and the activities, just say it! Casa Thomas Jefferson O Inglês Como Deve Ser Welcome The main purpose of this blog is to share activities to enhance the teacher's lesson plan. They will not replace the course book, but they will make the lessons more attractive and richer. Share your warm-up activity with movie segments too. You may email it to me at [email protected] and the activity will be credited to you with a link to your own site if it's the case. Give me suggestions for topics and segments too, please. Isn't sharing just fantastic? | Mid | [
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Economics and business books Main menu Post navigation Google, books and public value Already much has been written about the American court’s ruling in favour of Google being able to digitize millions of books without express permission from the copyright holder. The EFF warmly welcomed the ruling, other commentators have some reservations, and the Authors Guild has said it will appeal. Judge Denny Chin was absolutely clear, writing: “In my view, Google Books provides significant public benefits,” the ruling reads. “It advances the progress of the arts and sciences, while maintaining respectful consideration for the rights of authors and other creative individuals, and without adversely impacting the rights of copyright holders.” The judgement suggests Google Books will act like a store allowing people to browse before they go ahead and buy the book – that it will be an unusual example, in other words, of a monopoly in the public interest. Hmm. There is obvious potential for researchers and readers to benefit from increased access to books. It is possible that authors will benefit if searchability increases rather than decreases their sales – this is plausible but it is an empirical issue, so we will see. However, the ruling (on a quick read) ignores other potential side-effects. Google is a commercial company, not a public library, and the architecture it uses to present search results will not be based on the same kind of criteria. It may well divert people away from libraries, which are important social and cultural institutions. It may have a market impact in bookselling depending on the links given alongside search results – can retailers buy those slots? I don’t know. The e-book link is a solo link in the examples I looked at, taking you to pay in Google Play with Google Wallet. There will be other unintended consequences I’ve not thought of yet. If there is an appeal, it isn’t quite the end of the saga, but I think it is clear the game is probably over for the Authors Guild. However, the remaining delay gives Google time to reflect on how it implements Google Books – what are the principles, and what role does public service play in this initiative? Coincidentally, I spent this morning at a fascinating conference on public value organised by Channel 4 (talking about how the BBC Trust thinks about public value – here is a link to our publication on it, Public value in Practice). I believe commercial organisations can have a public purpose, that this has a large overlap with the profit motive, rather than conflicting with it. But it behoves Google as a massive commercial entity providing one of the most important public goods – knowledge – to tell us more about the principles by which it will run Google Books. By continuing to use the site, you agree to the use of cookies. more information The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this. | Mid | [
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Friday, 4 November 2011 Emotional or Managing it? In a classroom setting, a child gets reprimanded by his teachers for throwing a fit. At home, a child either gets a pep talk or disciplinary action from the parents. The child goes to bed and when he wakes up the next day, it is a whole new day. He goes back to school and the incident is put behind until it happens again. In the office, forgiveness either doesn’t come by easy or doesn’t come at all. The lapse in control of emotions or impulses can cause grave damage to one’s reputation, future and career. David Goleman, psychologist and award-winning author of Emotional Intelligence, defined Emotional Intelligence (EQ) as a set of skills, including control of one’s impulses, self-motivation, empathy and social competence in interpersonal relationships The workplace is a fast paced environment constantly consisting of stress and pressure. Everyone is fighting to keep afloat in the endless pile of work and the mounting pressure and now keeping a lookout of the emotions of others is in the equation? Not only does one have to maintain a high monitor on his emotions, impulses and reactions he has to manage, be in tuned and react accordingly to everyone that he is working with. That is EQ in a nutshell. It is really not that difficult. Some of it has been inculcated since young. If a child sees another crying child, he passes his own toy in bid to cheer him up. If a child senses his mother’s bad mood, he keeps his silence lest to aggravate it. But of course as a child, when angered, he lashes out without a second thought of the consequence. Adults, on the other hand, are better equipped with the ability to control and rein. It is simply that amidst the harsh money oriented world with so much more distraction, responsibilities and pressure, adults have grown to be less empathising and less inclined to care or be in tuned to emotions of others. In an organization, there is seldom a one man show. It takes more than just two hands to clap. There is an old saying that goes “Nothing runs better than a well-oiled machine”. If an organization that consists of different parts of a machine is well oiled and meshes together, productivity can only increase. EQ is a constant conscientious conscious effort on one’s part. It also has to be imparted and shared as knowledge to the rest. It is the making of a great leader. No comments: Post a Comment About me CBS is the leading training company specialising in next generation courses in the field of behavioral science, psychology, forensic and security courses. CBS serves as an important platform for the transfer and exchange of leading-edge knowledge and ideas which contributes to the transformation of lives of individuals, organizations and the society at large. | Mid | [
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How important is hepatitis C virus (HCV)-infection in persons with acute leukemia? Hepatitis C virus (HCV)-infection is common in persons with leukemia. Blood transfusions are the typical source and HCV-related chronic hepatitis a common outcome. Development of HCV-infection and -related hepatitis raises important questions about subsequent leukemia treatment including the natural history of the infection and need for treatment modification. Although the natural history of HCV-infection and -related hepatitis in this setting is unknown, data from normal persons with HCV-infection suggest that short-term survival is not likely to be decreased in persons with leukemia and these complications. In contrast, long-term survival may decrease because of a high rate of chronic hepatitis, cirrhosis, and possibly hepatocellular carcinoma. There are no convincing data that HCV-infection or -related hepatitis or alterations in anti-leukemia drug dose or schedule prompted by abnormal liver function tests, alter leukemia outcome. Consequently, it is uncertain whether drug doses and/or schedule should be modified in persons with leukemia and HCV-infection or -related hepatitis. Short-term outcome of blood cell and bone marrow transplants is also unaffected by HCV-infection or -related hepatitis. | Mid | [
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package org.specs2 package mock import specification._ import matcher._ import junit.framework.AssertionFailedError import org.specs2.fp.Monad class MockitoSpec extends script.Spec with Mockito with ResultMatchers with Groups { def is = s2""" Contexts ======== The Mockito trait is reusable in other contexts + in JUnit Issues ====== The following mockito issues are fixed + #584 NPE when setting expectations twice on a mockito mock + #603 classcast exception with smart return values + #679 any[T] matcher must work like org.mockito.ArgumentMatchers.any """ "callbacks" - new group { eg := { val s = new Mockito with JUnitExpectations { val list = mock[java.util.List[String]] def test = { list.add("one") there was one(list).add("two") 1 must_== 1 // to check if the previous expectation really fails } } s.test must throwAn[AssertionFailedError] } } "issues" - new group { eg := { trait Mockable { def method(list: List[String]): String } lazy val m = mock[Mockable] m.method(===(List[String]())).returns("Hello1") m.method(===(List[String]("2"))).returns("Hello2") m.method(List()) === "Hello1" m.method(List("2")) === "Hello2" } eg := { class MyDAO[M[_] : Monad] { def test: M[Int] = Monad[M].pure(0) } val m: MyDAO[Option] = mock[MyDAO[Option]].smart m.test returns Option(1) m.test must beSome(1) } eg := { class Test { def fn1(a: Int, b: Option[Int] = None): Int = a + b.getOrElse(0) } val test = mock[Test] test.fn1(anyInt, any[Option[Int]]).returns(3) test.fn1(100) ==== 3 } } } | Mid | [
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Recovery from severe hematopoietic suppression using recombinant human granulocyte-macrophage colony-stimulating factor. The ability of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) to enhance recovery of a radiation-suppressed hematopoietic system was evaluated in a nonuniform radiation exposure model using the rhesus monkey. Recombinant human GM-CSF treatment for 7 days after a lethal, nonuniform radiation exposure of 800 cGy was sufficient to enhance hematopoietic reconstitution, leading to an earlier recovery. Monkeys were treated with 72,000 U/kg/day of rhGM-CSF delivered continuously through an Alzet miniosmotic pump implanted subcutaneously on day 3. Treated monkeys demonstrated effective granulocyte and platelet levels in the peripheral blood, 4 and 7 days earlier, respectively, than control monkeys. Granulocyte-macrophage colony-forming unit (CFU-GM) activity in the bone marrow was monitored to evaluate the effect of rhGM-CSF on marrow recovery. Treatment with rhGM-CSF led to an early recovery of CFU-GM activity suggesting that rhGM-CSF acted on an earlier stem cell population to generate CFU-GM. Thus, the effect of rhGM-CSF on hematopoietic regeneration, granulocyte recovery, and platelet recovery are evaluated in this paper. | High | [
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World’s first Alpine high-speed rail Oct 12 What strikes me most about China’s stunning progress is its Speed and Scale. The country always thinks BIG and whatever it does, it employs enormous speed.The new high-speed train on high altitude is another instance of Chinese engineering skill. The new high-speed train will soon connect top cities in the high-altitude northeast region. This is the only high-speed railway in the world designed for a frozen, high-altitude region. On October 8, the test train left Harbin West station located in the capital of Heilongjiang province for Dalian, a port city of Liaoning province. And it reached its destination in just over three hours. The 921-km railway line connects 10 major cities in northeast China, such as Changchun, Tieling and Shenyang and cuts travel by nine hours. China has been running high speed trains to many destinations, including Beijing and Shanghai covering 1300 km in about four-and-a-half hours. But this is the first time it introduced the same in high-altitude sector. I travelled from Hangzhou to Beijing in a high-speed train in April this year. The train was running at 312km an hour and it was a mind-blowing experience. Talking about the high-speed train on the high altitude, Gao Baijiang, director, High-Speed Railway TECH Application Centre, said: “We used new cold-resistant materials and heat-tracing materials. They are energy efficient and keep the temperature in the train consistent and comfortable. We have used necessary engineering skills to prevent snow from disrupting the train’s operational system. And to achieve that, new snow-melting facilities have been installed in the equipment bay.” Th train can also withstand temperature as low as minus 40 degrees Celsius and summer temperature as high as 40 degrees Celsius. The train can carry over 550 people with 8 carriages. No fire can be used on the train. Food gets heated with microwaves. Special facilities will be there for the disabled. Their restrooms are two times the size of those for ordinary passengers. Zhao Wenguo, a top official from Shenyang Railway Bureau, said: “The opening of Harbin-Dalian high-speed railway means we have a more complete railway network in northeast China. The railway routes connect major cities in the region. It makes it more convenient for people to travel, and will help to revitalise the old industrial base in the region.” The train service is expected to be operational by the end of this year. | Mid | [
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Love this club Blackburn Rovers are believed to be in pursuit of Roberto Di Matteo to fill their managerial vacancy. The Championship club sacked Henning Berg on Tuesday night and Goal.com has already suggested that they are after former Chelsea boss Di Matteo to step into the role. The Italian, who has already been linked with the Nottingham Forest job, was sacked by the Blues last month despite leading the club to the Champions League/FA Cup double whilst caretaker at Stamford Bridge last season. Di Matteo has already coached in the second tier - with West Bromwich Albion in 2010 - but reports suggest he is unlikely to again drop down following his success in Europe's top competition. | Mid | [
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Trying To Puzzle Out Which Medical Health Insurance To Get Is Practically As Tough As Performing Your Own Taxes. You ... September 18, 2018 Teenagers usually by pass receiving health insurance since they truly feel they’re as well younger to obtain really ill. Nonetheless, there are actually top reasons to seek out medical care that don’t require illnesses - traumas and crashes can occur to anybody at all ages. You will find strategies particularly for more youthful people who can include these sorts of circumstances, generally by using a higher insurance deductible and minimize price than typical health care insurance. When traveling out of the status or out of your country, seek advice from your state of health insurance firm first to actually are covered for sickness or damage. Particularly if count on Medicare insurance for health insurance, you might not need to vacation significantly being outside your insurance plan company’s system. Prior to fill casino online being covered by your overall health insurance, check to see if there’s a a lot less-costly common software. Numerous huge local pharmacy stores and discounted retailers with pharmacy offer you low-cost generics of frequent prescription drugs. Dependant upon your insurance, it might actually be less costly to make use of that discounted rather than to submit your medication claim to your insurance plan. Ask your doctor to recommend you generic prescription drugs if someone is offered. Your co-shell out will usually be less for a generic drug than to get a name brand. The effects are exactly the same, you merely won’t pay an added surcharge for your labeled medicine. Save yourself the amount of money when possible. live casino terpercaya may possibly noise a little out of your package, but some people visit an insurance coverage dealer to get the best health insurance service provider. Numerous brokers have a very sizeable group at their hands, and they can attempt their very best to help you the ideal offers and discover you someone who suits all or most of your specs. Prior to re-registering along with your recent medical insurance organization, determine if their insurance policies are transforming. Some businesses are raising their costs, and when your own property is, you are going to truly feel it if you re-join. Examine around with some other insurance companies to successfully are still obtaining the best offer readily available. Prior to deciding to change your medical insurance prepare, determine in case your personal or family doctor is within the coverage. Some insurance firms is only going to include you if you use their medical doctors, so you may want to steer obvious in case your household medical doctor will not be an authorized one out of their system. Don’t wait until you need it to start out trying to find health care insurance. Not only can more companies decline you, but those who do agree to you will sometimes ask you for higher amounts. If you have a pre-current situation it may be quite challenging, or else difficult, to get affordable coverage to get a reasonable selling price. Tend not to rest about nearly anything when getting any adverse health insurance coverage. mukacasino.com will be attractive to omit specific particulars. Avoid the urge and become entirely sincere. A little bright white lie can certainly make your entire insurance policy worthless. You may not wish to discover youself to be stuck with the monthly bill if you get hospitalized and found in a rest. You need to ensure which you have totally investigated as numerous health care insurance ideas when you achievable can. An insurance coverage brokerage may be required in the event you don’t have the time or the want to undergo the big quantities of info. Also you can have a look at web sites focusing on looking at and picking insurance coverage that suit the customer’s demands. It is usually possible to pull away cash from your IRA and employ it to pay for your state of health insurance fees whenever you get rid of your work. You ought to contact an accountant to be certain you’re permitted to do this where you live, and to learn if you can find any penalties later on for doing the work. Your sole method to understanding health insurance and how for top level insurance coverage for the money is thru education. With any luck ,, this article has assisted you to gain greater insight and understanding of your choices, as they relate with the coverage of the well being and you are willing to understand your way to your excellent sound medical strategy. | Mid | [
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Unfortunately, the information our research department originally obtained from 3M regarding when Post-it notes were first sold was incomplete. As a result of new information we have received from 3M, we feel it is only fair to give our contestants, Gabe and Brittany, another shot to play 'Million Dollar Money Drop' even though this question was not the deciding question in their game. We would like to extend our sincere thanks to the viewers who brought this to our attention, and we're thrilled to give Gabe and Brittany the opportunity to return to play the game. | Low | [
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374 F.3d 529 Marietta TAYLOR, Plaintiff-Appellant,v.FEDERAL NATIONAL MORTGAGE ASSOCIATION, Waterfield Mortgage Company, and Burke, Costanza & Cuppy, Llp, Defendants-Appellees. No. 03-3320. United States Court of Appeals, Seventh Circuit. Argued February 12, 2004. Decided July 2, 2004. As Amended on Denial of Rehearing and Suggestion for Rehearing En Banc August 3, 2004. COPYRIGHT MATERIAL OMITTED Zena D. Crenshaw (argued), Gary, IN, for Plaintiff-Appellant. Thomas A. Herr, Michael H. Michmerhuizen (argued), Barrett & McNagny, Fort Wayne, IN, Kathryn D. Schmidt (argued), Burke, Costanza & Cuppy, Merrillville, IN, for Defendants-Appellees. Before CUDAHY, COFFEY and ROVNER, Circuit Judges. CUDAHY, Circuit Judge. 1 Plaintiff-Appellant Marietta Taylor lost her home in a foreclosure action brought in the Superior Court of Lake County, Indiana by the Federal National Mortgage Association (Fannie Mae) and Waterfield Mortgage Company (Waterfield) through the law firm of Burke, Costanza & Cuppy, LLP (BCC) (collectively, the Defendants). Rather than directly appealing this judgment, Taylor filed a suit in state court alleging that the Defendants had committed extrinsic fraud and a fraud upon the court by instituting a wrongful foreclosure action against her in violation of two federal statutes. After the Defendants removed the case to federal court, the district court dismissed Taylor's suit with prejudice for lack of subject matter jurisdiction because it implicated the Rooker-Feldman doctrine. Taylor now appeals, but for the following reasons, we affirm. I. 2 When Taylor's husband died, her Social Security disability payments were temporarily suspended, though they were guaranteed by the Social Security Administration. Having no other income, she was unable to make timely payments on her mortgage and consequently fell behind on her account. In November 1998, Taylor received an offer of assistance with her monthly mortgage payment from the Calumet Township Trustee (the Trustee). But although the Trustee tendered payments for February 1999 and April-November 1999, these payments were refused because the loan had entered foreclosure, and Taylor needed to pay attorney's fees of $1,235 in order to cure the foreclosure action before her account (which was approximately $2,000 in arrears as of December 30, 1999) could be brought up to date. Fannie Mae and Waterfield ultimately obtained a judgment of foreclosure from the Lake County Superior Court. 3 Instead of appealing this judgment, on August 21, 2002, Taylor filed a "Complaint to Vacate Judgment and for Compensatory As Well As Punitive Damages Based On Fraud Upon the Court" (Complaint) in Lake County Superior Court, claiming that the Defendants had committed a fraud upon the court by instituting a wrongful foreclosure action against her, which itself was alleged to have been in violation of the Equal Credit Opportunity Act (ECOA), 15 U.S.C. § 1691 et seq., and 42 U.S.C. § 1985. The Defendants removed the case to federal court and then moved to dismiss pursuant to Rule 9(b) of the Federal Rules of Civil Procedure for failure to plead her fraud claim with specificity. 4 Upon the district court's review of the Defendants' motion to dismiss, a jurisdictional question arose: whether the Rooker-Feldman doctrine barred subject matter jurisdiction over the case. After the parties briefed the issue, the district court found that Taylor had requested the federal court to set aside the state court's judgment of foreclosure and that the Rooker-Feldman doctrine thus barred her suit. Moreover, the district court found that even if Taylor "recast the complaint another way, we would still be constrained to find that the action is inextricably intertwined with the state court judgment." (Appellant's Appx. at 27.) The district court found that the injury of which Taylor complained was caused by the state court's judgment of foreclosure, not by the acts of the Defendants. Since Taylor was found to have had a reasonable opportunity to raise her claims and to challenge the foreclosure in state court, the district court dismissed Taylor's suit with prejudice for lack of subject matter jurisdiction pursuant to the Rooker-Feldman doctrine and remanded it to the state court from whence it came. II. 5 We review de novo a district court's determination that it lacks subject matter jurisdiction based on the Rooker-Feldman doctrine. Brokaw v. Weaver, 305 F.3d 660, 664 (7th Cir.2002). The Rooker-Feldman doctrine derives its name from two decisions of the United States Supreme Court, Rooker v. Fidelity Trust Co., 263 U.S. 413, 44 S.Ct. 149, 68 L.Ed. 362 (1923), and District of Columbia Court of Appeals v. Feldman, 460 U.S. 462, 103 S.Ct. 1303, 75 L.Ed.2d 206 (1983). Simply put, the Rooker-Feldman doctrine "precludes lower federal court jurisdiction over claims seeking review of state court judgments ... [because] no matter how erroneous or unconstitutional the state court judgment may be, the Supreme Court of the United States is the only federal court that could have jurisdiction to review a state court judgment." Brokaw, 305 F.3d at 664. Therefore, if a claim is barred by the Rooker-Feldman doctrine, the federal court lacks subject matter jurisdiction over the case. Id. 6 In applying the Rooker-Feldman doctrine, the immediate inquiry is whether the "federal plaintiff seeks to set aside a state court judgment or whether he is, in fact, presenting an independent claim." Kamilewicz v. Bank of Boston Corp., 92 F.3d 506, 510 (7th Cir.1996). Claims that directly seek to set aside a state court judgment are de facto appeals and are barred without additional inquiry. However, federal claims presented to the district court that were not raised in state court or that do not on their face require review of a state court's decision may still be subject to Rooker-Feldman if those claims are "inextricably intertwined" with a state court judgment.1 See Brokaw, 305 F.3d at 664. While "inextricably intertwined" is a somewhat metaphysical concept, the "crucial point is whether `the district court is in essence being called upon to review the state-court decision.'" Ritter v. Ross, 992 F.2d 750, 754 (7th Cir.1993) (quoting Feldman, 460 U.S. at 483-84 n. 16, 103 S.Ct. 1303). The determination hinges on whether the federal claim alleges that the injury was caused by the state court judgment, or, alternatively, whether the federal claim alleges an independent prior injury that the state court failed to remedy. See Long v. Shorebank Development Corp., 182 F.3d 548, 555 (7th Cir.1999). 7 Once we have determined that a claim is inextricably intertwined, i.e., that it indirectly seeks to set aside a state court judgment, we must then determine whether "the plaintiff did not have a reasonable opportunity to raise the issue in state court proceedings." Brokaw, 305 F.3d at 668 (citing Long, 182 F.3d at 558). Here, if the plaintiff could have raised the issue in state court proceedings, the claim is barred under the Rooker-Feldman doctrine. If not, the suit is free to proceed in federal court (subject to any claim preclusion defenses). To establish that they did not have a reasonable opportunity to raise an issue in state court, federal litigants must 8 point[] to some factor independent of the actions of the opposing party that precluded the litigants from raising their federal claims during the state court proceedings. Typically, either some action taken by the state court or state court procedures in place have formed the barriers that the litigants are incapable of overcoming in order to present certain claims to the state court. 9 Long, 182 F.3d at 558. 10 A. Are Taylor's claims independent? 11 Taylor's first claim is that a fraud was perpetrated on the state court that granted the judgment of foreclosure. Although the relief Taylor prays for in her complaint with respect to all three of her claims is "to recover her home, or equal monetary value plus interest of 10% per annum, plus punitive damages," (Appellant's Appx. at 12, 13), the relief granted when a claim of fraud on the court succeeds is that the party claiming fraud is relieved from the judgment, i.e., the judgment is set aside. See Ind. Trial Rule 60(B)(3) ("On motion and upon such terms as are just the court may relieve a party or his legal representative from an entry of default, final order, or final judgment, including a judgment by default, for ... fraud (whether heretofore denominated intrinsic or extrinsic), misrepresentation, or other misconduct of an adverse party."). The district court correctly determined that requesting the recovery of her home is tantamount to a request to vacate the state court's judgment of foreclosure, the form in which Taylor's complaint in state court was in fact styled, and that the Rooker-Feldman doctrine barred granting that relief. See Facio v. Jones, 929 F.2d 541, 543 (10th Cir.1991) (holding that a plaintiff's federal action seeking to "vacate" a state court judgment was a de facto appeal and thus barred under the Rooker-Feldman doctrine). 12 Both of Taylor's claimed federal statutory violations, on the other hand, allow for money damages. See 15 U.S.C. § 1691e(a)-(b) (allowing civil actions under the ECOA for actual and punitive damages); 42 U.S.C. § 1985(3) (a party claiming a conspiracy to deprive her of civil rights "may have an action for the recovery of damages, occasioned by such injury or deprivation"). While recovery of her home is not available through these claims for the same reason her fraud claim is barred, the monetary damages Taylor claims are compensatory damages in the amount of the value of her home plus 10% interest per annum and punitive damages. The fact that Taylor is claiming compensatory damages in the amount of the value of her home (plus interest) demonstrates that her asserted injury is the loss of her home due to the Defendants' conspiracy to deprive her of her home, not an independent injury arising from acts of the Defendants.2 This bars her § 1985 claim. See Brokaw, 305 F.3d at 667 (noting, in discussing Long, 182 F.3d at 557, that since "absent the eviction order, Long would not have suffered the injuries for which she now seeks to be compensated," her due process claims appeared to be barred under Rooker-Feldman); Long v. Shorebank Dev. Corp., 182 F.3d 548, 557 (7th Cir.1999) ("[A] litigant may not attempt to circumvent the effect of Rooker-Feldman and seek a reversal of a state court judgment simply by casting the complaint in the form of a civil rights action."); Wright v. Tackett, 39 F.3d 155, 157 (7th Cir.1994) (finding in factually similar case that constitutional claims wre inextricably intertwined with state court's denial of plaintiff's request to intervene in foreclosure action). 13 As for Taylor's ECOA claim, it is distinguishable from the situation in which we have allowed plaintiffs to proceed with federal claims because the asserted violations were "independent of and complete prior to the entry" of the challenged state order. Long v. Shorebank Dev. Corp., 182 F.3d 548, 556 (7th Cir.1999). Here, Taylor characterizes her case as "[f]undamentally... an action for extrinsic fraud and fraud on a court" (Taylor's Br. at 6) and her claimed ECOA violation as an element of her fraud claim (i.e., as a defense to the foreclosure).3 Her injuries arose not from an independent violation of her rights but from the extrinsic fraud upon the state court and intentional deprivation of her property that she claims occurred due to that violation. Moreover, as an element of her claim of fraud upon the state court, her ECOA violation is inextricably intertwined with the determination of her fraud claim and is likewise barred by Rooker-Feldman. B. Reasonable opportunity 14 We have held that "[w]hile the Rooker-Feldman doctrine bars federal subject matter jurisdiction over issues raised in state court, and those inextricably intertwined with such issues, `an issue cannot be inextricably intertwined with a state court judgment if the plaintiff did not have a reasonable opportunity to raise the issue in state court proceedings.'" Brokaw, 305 F.3d at 668 (quoting Long, 182 F.3d at 558). The "reasonable opportunity" inquiry focuses not on ripeness, but on difficulties caused by "factor[s] independent of the actions of the opposing part[ies] that precluded" a plaintiff from bringing federal claims in state court, such as state court rules or procedures. Long, 182 F.3d at 558. 15 Frankly, both the parties and the district court seem a bit confused about what the "reasonable opportunity" was, or is, in this case. This is not surprising, since we are faced with somewhat unusual circumstances with respect to this portion of our analysis. Usually, Rooker-Feldman is raised by defendants when a disappointed state court litigant brings suit in federal court to overturn the state court decision, or by plaintiffs when a defendant seeks removal of a state suit to federal court. Here, Taylor did sue in state court, but her suit was removed by the Defendants to federal court (apparently without any objection from Taylor) under asserted federal question jurisdiction. Once the district court raised the Rooker-Feldman doctrine as a potential bar to its subject matter jurisdiction, the Defendants admitted that Rooker-Feldman applied to bar federal jurisdiction, while Taylor had latched onto the federal venue and argued that her suit should remain in federal court. Taylor appealed the district court's dismissal of her suit because she is concerned that her claims might be issue-precluded on remand, leaving her case "unduly postured for a state-court dismissal." (Appellant's Br. at 12.) Taylor's concern is apparently the product of the district court's determination that she had had a reasonable opportunity to bring her claims in the state court foreclosure proceedings and to challenge the foreclosure. 16 Although we agree with the district court that Taylor has shown no barriers preventing her from bringing her claims in state court, and we therefore find that the district court's decision to remand for lack of subject matter jurisdiction was correct, we must attempt to allay Taylor's concern that her suit will be precluded on remand. Taylor's fear (and her desire to remain in federal court) seems to stem from confusion about the relationship of the Rooker-Feldman doctrine to the doctrine of res judicata, which, as we have previously noted, "are not coextensive." GASH Assoc. v. Rosemont, 995 F.2d 726, 728 (7th Cir.1993). We have held that "[w]here Rooker-Feldman applies, lower federal courts have no power to address other affirmative defenses, including res judicata.... [W]e ... recognize[] that the Rooker-Feldman doctrine should not be confused with res judicata (which we sometimes term `preclusion') and that where Rooker-Feldman applies, the res judicata claim must not be reached." Garry v. Geils, 82 F.3d 1362, 1365 (7th Cir.1996). Our belief that no barriers exist to preclude Taylor from bringing her claims in state court is based on her failure to make us aware of any state laws, state court procedures or other impediments that would stand in the way of her bringing her claims in state court proceedings. Cf. Brokaw, 305 F.3d at 662-63 (finding that since minor plaintiff was not appointed a guardian at litem and was not allowed to appear at state court hearing where child abuse allegations determined, she did not have reasonable opportunity to bring constitutional claims in state court child neglect proceedings); Long, 182 F.3d at 559-60 (finding that the plaintiff did not have a reasonable opportunity to raise her federal claims in the state court eviction proceeding because Illinois law precluded her from doing so). We have not determined that Taylor is barred by res judicata because she could have or should have brought her claims as part of the foreclosure proceedings; the res judicata issue (if there is one) is for the state court to determine on remand.4 Conclusion 17 Because Taylor's claims are all either de facto appeals of, or are inextricably intertwined with, the state court's judgment of foreclosure, and because she has failed to demonstrate any barriers preventing the consideration of her claims by the state court, the district court was correct that the Rooker-Feldman doctrine deprived it of subject matter jurisdiction over her suit. The dismissal with prejudice of Taylor's suit was thus appropriate, and the district court's order remanding her case to state court, where she will have the opportunity to bring her claims, is AFFIRMED. Notes: 1 Even though theRooker-Feldman doctrine does not apply to claims that are neither de facto appeals nor are inextricably intertwined with a state court judgment, these claims may still be barred as claim-precluded under res judicata if the plaintiff litigated them (or could have litigated them) in state court proceedings. See Rizzo v. Sheahan, 266 F.3d 705, 713-14 (7th Cir.2001) (If "the injury alleged is distinct from that judgment, i.e., the party maintains an injury apart from the loss in state court and not `inextricably intertwined' with the state judgment ... res judicata may apply, but Rooker-Feldman does not.... Also known as claim preclusion, res judicata is an affirmative defense designed to prevent the relitigation of claims that were or could have been asserted in an earlier proceeding.") (internal quotations and citations omitted). 2 If, as a hypothetical example, attorney's fees were wrongfully added to the balance Taylor owed on her mortgage in violation of the ECOA, and if, when her home was sold at foreclosure, the attorney's fees were withheld from any balance owed to her, then she might have an independent claim for money damages in the amount of the wrongfully imposed attorney's fees. But she does not claim any such wrongful action or other independent injury 3 See, e.g., Taylor's Br. at 4-5 (ECOA and § 1985 violations constituted the "fraud, accident or mistake which prevented the defendant in the judgment from obtaining the benefit of his defense"; Taylor's Reply Br. at 6 ("Taylor contends that the operative `fraud' constitutes a violation of [ECOA] and 42 U.S.C. § 1985."); Taylor's Short Appx. at 12 ("[D]efendant's (sic) ... knew they were intentionally, as part of a conspiracy, combination and agreement[,] acting to deprive the plaintiff of her property, violating the Equal Credit Opportunity act."). 4 Although we may not consider the issue of res judicata because we lack the subject matter jurisdiction to do so, we note that Indiana allows independent actions for fraud on the court to be brought at any time after judgment has been enteredSee Stonger v. Sorrell, 776 N.E.2d 353, 357 (Ind.2002) (adopting federal authority in analyzing claims of fraud on the court under Indiana Trial Rule 60(B), which holds that there is no time limit on bringing independent actions for fraud on the court, though claims may be barred by laches). The fact that the Defendants erroneously attempted to remove Taylor's suit to federal court should not have any bearing on the state court's analysis. | Mid | [
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from os.path import dirname import operator from decimal import * import csv import os.path import os from datetime import datetime from dbfpy import dbf from optparse import make_option from django.core.management.base import BaseCommand, CommandError from treemap.models import Resource class Command(BaseCommand): args = '<input_file_name, column_name>' option_list = BaseCommand.option_list + ( make_option('--verbose', action='store_true', dest='verbose', default=False, help='Show verbose debug text'), ) def write_headers_if_needed(self): if not self.wrote_headers: self.err_writer.writerow(self.headers) self.wrote_headers = True def get_dbf_rows(self, in_file): reader = dbf.Dbf(in_file) print 'Opening input file: %s ' % in_file self.headers = reader.fieldNames print 'Converting input file to dictionary' rows = [] for dbf_row in reader: d = {} for name in self.headers: d[name] = dbf_row[name] rows.append(d) return rows def get_csv_rows(self, in_file): reader = csv.DictReader(open(in_file, 'r' ), restval=123) print 'Opening input file: %s ' % in_file rows = list(reader) self.headers = reader.fieldnames return rows def name2column(self, name): match_dict = { "AQ_NOx_avoided.csv": "aq_nox_avoided_dbh", "AQ_PM10_avoided.csv": "aq_pm10_avoided_dbh", "AQ_SOx_dep.csv": "aq_sox_dep_dbh", "CO2_avoided.csv": "co2_avoided_dbh", "Electricity.csv": "electricity_dbh", "AQ_NOx_dep.csv": "aq_nox_dep_dbh", "AQ_PM10_dep.csv": "aq_pm10_dep_dbh", "AQ_VOC_avoided.csv": "aq_voc_avoided_dbh", "CO2_sequestered.csv": "co2_sequestered_dbh", "Hydro_Interception.csv": "hydro_interception_dbh", "AQ_Ozone_dep.csv": "aq_ozone_dep_dbh", "AQ_SOx_avoided.csv": "aq_sox_avoided_dbh", "BVOC.csv": "bvoc_dbh", "CO2_storage.csv": "co2_storage_dbh", "Natural_Gas.csv": "natural_gas_dbh" } if name in match_dict: return match_dict[name] else: raise Exception("You must either provide a standard " "itree name (see below) or provide the " "database column to write to. \n\n" "Possible csv names: %s\n" % match_dict.keys() + "Possible columns: %s\n" % match_dict.values()) def handle(self, *args, **options): try: self.verbose = options.get('verbose') self.file_name = args[0] if os.path.isdir(self.file_name): self.process_dir(self.file_name) else: if len(args) == 1: self.column_name = self.name2column(os.path.split(self.file_name)[1]) else: self.column_name = args[1] self.process_file(self.file_name) except Exception, e: raise print "Arguments: Input_File_Name.[dbf|csv], column name" print "Options: --verbose" def process_dir(self, adir): for f in os.listdir(adir): try: if f.endswith(".csv"): f = adir + f self.column_name = self.name2column(os.path.split(f)[1]) self.file_name = f print "Processing %s (%s)" % (f, self.column_name) self.process_file(f) except Exception, e: raise pass def process_file(self, in_file): self.wrote_headers = False in_file = self.file_name err_file = in_file + ".err" self.err_writer = csv.writer(open(err_file, 'wb')) if self.file_name.endswith('.csv'): rows = self.get_csv_rows(in_file) if self.file_name.endswith('.dbf'): rows = self.get_dbf_rows(in_file) print 'Importing %d species' % len(rows) for i, row in enumerate(rows): self.handle_row(row) j = i + 1 if j % 50 == 0: print 'Loaded %d...' % j self.log_verbose("item %d" % i) print "Finished data load. " def log_verbose(self, msg): if self.verbose: print msg def log_error(self, msg, row): print "ERROR: %s" % msg columns = [row[s] for s in self.headers] self.write_headers_if_needed(self) self.err_writer.writerow(columns) def check_resource(self, row): # locate the species and instanciate the tree instance if not row["code"]: self.log_verbose(" No code column found") return (False, None) code = row['code'] self.log_verbose(" Looking for species code: %s" % code) found = Resource.objects.filter(meta_species__iexact=code) if found: #species match found self.log_verbose(" Found species code %r" % found[0]) return (True, found[0]) #species data but no match, add it self.log_verbose(" Adding unknown species code %s " % code) resource = Resource(meta_species=code, region="NorthernCalifornia") return (True, resource) def handle_row(self, row): self.log_verbose(row) # check the species (if any) ok, resource = self.check_resource(row) if not ok: return dbh_list = [3.81,11.43,22.86,38.10,53.34,68.58,83.82,99.06,114.3] if len(row)-1 > 10: dbh_list = [2.54,5.08,7.62,10.16,12.7,15.24,17.78,20.32,22.86,25.4,27.94,30.48,33.02,35.56,38.1,40.64,43.18,45.72,48.26,50.8,53.34,55.88,58.42,60.96,63.5,66.04,68.58,71.12,73.66,76.2,78.74,81.28,83.82,86.36,88.9,91.44,93.98,96.52,99.06,101.6,104.14,106.68,109.22,111.76,114.3] data = [] for dbh in dbh_list: for value in row: if value == 'code': continue test = float(value) if dbh == test: data.append(float(row[value])) self.log_verbose(" Final data %s" % data) setattr(resource, self.column_name, data.__str__()) resource.save() | Low | [
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Donald Trump has surveyed the wreckage of decades of failed Israeli-Palestinian diplomacy, considered the world full of challenges his administration faces, and somehow concluded that . . . he’s going to be the president who brokers a comprehensive Mideast deal. “It might be a bigger and better deal than people in this room even understand,” he proclaimed last week at a news conference with Israeli Prime Minister Benjamin Netanyahu. What is it about the Holy Land that inspires such messianism? Perhaps the question answers itself. In any case, Trump’s outsize diplomatic ambition is hardly unique. In fact, it bears a striking resemblance to that of John Kerry and Barack Obama. For American leaders, the shining allure of the Israeli-Palestinian peace prize appears to induce blindness to the conditions on the ground; deafness to expert advisers who point out that a grand initiative will be doomed to failure; and an irrational conviction that a new American strategy for peace can suddenly make success possible. By the time Obama took office in 2009, the prospects for a deal on a Palestinian state were already moribund, thanks in large part to the leaders of the two sides: Netanyahu and Palestinian President Mahmoud Abbas, who in addition to despising each other were unwilling and politically unable to make the necessary concessions. Eight years later, both are still in place, only weaker and even more intransigent than before. Not to worry, concluded Obama: He could succeed where others had failed by exercising a bit of U.S. tough love with Israel, starting with a demand for a total freeze on settlement construction in the West Bank. That, combined with his outreach to the Muslim world, would allow a peace deal to be struck within two years. Obama’s plan soon flopped, for the very reason his expert advisers warned him it would: U.S. pressure would never induce Israel to entirely freeze settlement construction. That gave Abbas the excuse he was looking for to refuse negotiations. (Sarah Parnass/The Washington Post) Then came Kerry, whose theory was that both sides would bow to what Washington sees as the inevitable terms of a settlement. They just needed someone, such as him, with the political skills and tireless dedication to make them do it. An exhausting year later, the experts were proved right again: Neither Netanyahu nor Abbas accept the U.S. outline, even as a vague basis for further negotiations. Now it’s Trump, who like Obama seems to think that the United States should pare back its global commitments and stop trying to nation-build — except when it comes to the Israelis and Palestinians. Once again the seasoned experts are sounding their warnings: “Today, unfortunately, the conditions are not set for a peace agreement, given an unprecedented gulf between the two sides,” report Mideast veterans David Makovsky and Dennis Ross. “Neither Israelis nor Palestinians at this moment believe that peace is either possible or desirable,” writes another, Martin Indyk. Never mind, says Trump: He has a new concept! Actually, it’s an old one rewarmed by Netanyahu, who last year proposed that Israel build on its common interests with Sunni states such as Egypt, Jordan and Saudi Arabia, which also are focused on containing Iranian expansionism and destroying Islamic jihadists. Along the way, they might agree on a peace deal in which Muslim regimes finally recognize Israel in exchange for concessions to the Palestinians. “It is something that is very different, hasn’t been discussed before” was Trump’s naive account. “And it’s actually a much bigger deal, a much more important deal, in a sense. It would take in many, many countries and it would cover a very large territory.” In reality, the idea dates to 2002, when a proposal by Saudi Arabia for relations with Israel in exchange for its withdrawal from occupied territories was adopted by the Arab League. That it has gone nowhere since then is telling: Arab governments are not prepared to negotiate on behalf of the Palestinians, much less endorse terms for a settlement that Abbas would reject. The process would work only if Israel and the Palestinians simultaneously reached agreement — which, for now, they can’t and won’t. Makovsky and Ross have a sensible suggestion: Instead of aiming for a Mideast home run, perhaps this administration should try for a few solid singles. One could be persuading Netanyahu to limit settlement construction to areas inside the security barrier Israel has built near its border with the West Bank; another would be getting Palestinians to stop paying subsidies to the families of militants who carry out violent attacks against Israelis. A few such steps might gradually create a better diplomatic climate and at least preserve the option of Palestinian statehood for the future. Of course, Trump would gain no peace prizes or boasting rights — but he would avoid becoming another Middle East loser. Read more from Jackson Diehl’s archive, follow him on Twitter or subscribe to his updates on Facebook. | Low | [
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<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd"> <html xmlns="http://www.w3.org/1999/xhtml"> <head> <meta http-equiv="Content-Type" content="text/xhtml;charset=UTF-8"/> <meta http-equiv="X-UA-Compatible" content="IE=9"/> <meta name="generator" content="Doxygen 1.8.13"/> <meta name="viewport" content="width=device-width, initial-scale=1"/> <title>fastText: Class Members</title> <link href="tabs.css" rel="stylesheet" type="text/css"/> <script type="text/javascript" src="jquery.js"></script> <script type="text/javascript" src="dynsections.js"></script> <link href="navtree.css" rel="stylesheet" type="text/css"/> <script type="text/javascript" src="resize.js"></script> <script type="text/javascript" src="navtreedata.js"></script> <script type="text/javascript" src="navtree.js"></script> <script type="text/javascript"> $(document).ready(initResizable); </script> <link href="search/search.css" rel="stylesheet" type="text/css"/> <script type="text/javascript" src="search/searchdata.js"></script> <script type="text/javascript" src="search/search.js"></script> <link href="doxygen.css" rel="stylesheet" type="text/css" /> </head> <body> <div id="top"><!-- do not remove this div, it is closed by doxygen! --> <div id="titlearea"> <table cellspacing="0" cellpadding="0"> <tbody> <tr style="height: 56px;"> <td id="projectlogo"><img alt="Logo" src="favicon.png"/></td> <td id="projectalign" style="padding-left: 0.5em;"> <div id="projectname">fastText  <span id="projectnumber">d00d36476b15</span> </div> <div id="projectbrief">Fast text processing tool/library</div> </td> </tr> </tbody> </table> </div> <!-- end header part --> <!-- Generated by Doxygen 1.8.13 --> <script type="text/javascript"> var searchBox = new SearchBox("searchBox", "search",false,'Search'); </script> <script type="text/javascript" src="menudata.js"></script> <script type="text/javascript" src="menu.js"></script> <script type="text/javascript"> $(function() { initMenu('',true,false,'search.php','Search'); $(document).ready(function() { init_search(); }); }); </script> <div id="main-nav"></div> </div><!-- top --> <div id="side-nav" class="ui-resizable side-nav-resizable"> <div id="nav-tree"> <div id="nav-tree-contents"> <div id="nav-sync" class="sync"></div> </div> </div> <div id="splitbar" style="-moz-user-select:none;" class="ui-resizable-handle"> </div> </div> <script type="text/javascript"> $(document).ready(function(){initNavTree('functions_r.html','');}); </script> <div id="doc-content"> <!-- window showing the filter options --> <div id="MSearchSelectWindow" onmouseover="return searchBox.OnSearchSelectShow()" onmouseout="return searchBox.OnSearchSelectHide()" onkeydown="return searchBox.OnSearchSelectKey(event)"> </div> <!-- iframe showing the search results (closed by default) --> <div id="MSearchResultsWindow"> <iframe src="javascript:void(0)" frameborder="0" name="MSearchResults" id="MSearchResults"> </iframe> </div> <div class="contents"> <div class="textblock">Here is a list of all class members with links to the classes they belong to:</div> <h3><a id="index_r"></a>- r -</h3><ul> <li>readFromFile() : <a class="el" href="classfasttext_1_1Dictionary.html#ae6471357f52b274416fb0544fb3ed136">fasttext::Dictionary</a> </li> <li>readWord() : <a class="el" href="classfasttext_1_1Dictionary.html#a1b79df8326dd9d7288a148db0948447d">fasttext::Dictionary</a> </li> <li>retrain : <a class="el" href="classfasttext_1_1Args.html#a3bfb953b0cfe153207ad75c757af292b">fasttext::Args</a> </li> <li>right : <a class="el" href="structfasttext_1_1Node.html#a8a02d78386d6837a20858269bf9c6366">fasttext::Node</a> </li> <li>rng : <a class="el" href="classfasttext_1_1Model.html#a7e27d2fd2800dcee09ea8101fea49676">fasttext::Model</a> , <a class="el" href="classfasttext_1_1ProductQuantizer.html#af5755b1c5ed3128430f1c1de2c03ac26">fasttext::ProductQuantizer</a> </li> </ul> </div><!-- contents --> </div><!-- doc-content --> <!-- start footer part --> <div id="nav-path" class="navpath"><!-- id is needed for treeview function! --> <ul> <li class="footer">Generated by <a href="http://www.doxygen.org/index.html"> <img class="footer" src="doxygen.png" alt="doxygen"/></a> 1.8.13 </li> </ul> </div> </body> </html> | Low | [
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My (new) scenic ride to work 1 Just over a year ago, I moved to Canterbury. Ironically, just as NSW mergers of local government areas brought into being an officially designated “Inner West,” after over 30 years (leaving aside my Perth sojourn) I am no longer living there. That was a bit of a blow to my geographical self-respect (self-regard some may say). It also means that I am one big hill further away from the city. As age takes its toll, that has proved an obstacle to a bicycle commute. Maybe one day I will surmount that. Meanwhile, when time and weather permit, I can ride to Sydenham and take a fast and more frequent train from there. This is my new scenic ride (half way) to work. It takes me mostly along a stretch of the Cooks River cycleway. That’s the detention pond near the mouth of Cup and Saucer Creek, not long after I join the path on the south side of the river. When I took this picture it was full of unsightly green algae. It has since cleared up. This is a distant view of the old sugar mill, now converted to flats: I usually cross the river at this point: There is a small harbour which must have been used for the sugar mill: An area is fenced off to protect birds basking in the sun from pesky people. I suppose I got too close for comfort. It was difficult to catch a good photo of this, but you can detect the main stream of the river from the plastic water bottles and other flotsam floating up and down along it with the tide. Here at least some street rubbish has been captured at the end of a stormwater drain: though as we know it is but a drop in the ocean. The path continues past sometimes flood-prone land and (I’m being botanically imprecise here) pleasing stands of paperbarks which I guess find that congenial. After passing playing fields and some decommissioned tennis courts, the path crosses the Cooks River again on a bridge which is definitely in need of renewal. This brings the path back to the southern side of the Cooks River. There is a mosque. The path crosses Wardell Road and there are more playing fields and a tennis court which is often being played on until quite late at night. A new bridge crosses over again just near the Marrickville Golf Course clubhouse: I ride past the club house and out of the golf course, cross the bottom of Illawara Road and come to Steel Park. Even if I’m not really thirsty, I always pause for a drink of water here on principle. Because it’s free. Like this: LikeLoading... Related This entry was posted on June 11, 2017 at 11:55 am and is filed under Australia. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site. 2 Responses to “My (new) scenic ride to work 1” Ken, I too am wondering as I contemplate that extra hill. I see them about more and more and people who ride them tell me they still actually do a bit of pedalling themselves – it’s probably a matter of self-discipline. I would imagine with an e-bike one could do a longer trip than my present semi-commute but with the same relatively mildly pulse-raising and endorphin-inducing effect. More importantly and especially for Sydney, if you live in a hilly neighbourhood (as I suspect you do) the e-assistance could make riding viable. | Mid | [
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Tuning Photophysical and Electrochemical Properties of Phosphorescent Heteroleptic Iridium Complex Salts-as Chemosensors. Photophysical and electrochemical studies of cyclometalated cationic heteroleptic iridium(III) complex salts have been carried out. For these complex salts the intense absorption bands appeared around 263 nm and are assigned to spin-allowed π-π* transitions of phenanthroline ligands. Moderately intense and weak absorption bands observed around 341 and 440 nm, respectively. These bands are assigned to spin-allowed metal to ligand charge transfer (1)MLCT and (3)MLCT transitions, respectively. The influence of anions and proton on the photophysical and electrochemical studies were also carried out. The emission wavelength was red shifted and emission color changed from yellow to red by the addition of CF3CO2H. The solution color changed from green to brown and the emission was quenched by the addition anions such as of F(-), CH3COO(-) and H2PO4(-). | Mid | [
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Giants send Cox into retirement with Game 5 win ATLANTA (AP) — The San Francisco Giants couldn’t wait to get to the champagne, to pop the cork on a celebration eight years in the making. But first, they had to pay their respects to the guy in the other dugout. Bobby Cox’s career ended when the Atlanta Braves lost to the Giants 3-2 in the deciding game of the NL division series Monday night, giving San Francisco its first playoff victory since a run to the World Series in 2002. The chants of “Bobby! Bobby! Bobby!” from the crowd at Turner Field were to be expected for a retiring manager who’s sure to wind up in Cooperstown. The more touching gesture was provided by the Giants, who quit jumping around long enough to clap for Cox and tip their caps in his direction. Story continues below advertisement. “He’s a legend in this sport,” second baseman Freddy Sanchez said. “He’s been a great mentor to so many people in the sport. We had to show our respect. First things first. Then we could go celebrate.” They certainly had reason. Twenty-one-year-old rookie Madison Bumgarner pitched six strong innings. Late-season pickup Cody Ross homered and drove in the go-ahead run with a two-out single in the seventh. Finally, the San Francisco bullpen closed out a series that was tight and tense to the very end. The Braves coaxed two walks out of San Francisco closer Brian Wilson in the bottom of the ninth, but they couldn’t get the hit that might’ve extended Cox’s career for at least one more game. Omar Infante struck out on a checked swing, and Melky Cabrera hit a routine grounder to third. Just like that, it was over. The Giants were moving on to face two-time NL champion Philadelphia in the league championship series. Cox was hanging up that familiar No. 6 uniform for the final time. “It doesn’t feel like the last time I’m putting it on, but it certainly is,” he said, his voice cracking. “I won’t put it on again.” Every game was decided by one run, but the Giants won three of them to take the best-of-five series and earn a shot at knocking off the mighty Phillies. Game 1 is Saturday at Philadelphia and features a marquee matchup of Cy Young winners: Tim Lincecum vs. Roy Halladay. Lincecum beat the Braves with a two-hit, 14-strikeout shutout in Game 1. Halladay pitched a no-hitter against Cincinnati in his postseason debut, getting the Phillies started on a sweep of the Reds. “They have unbelievable pitching,” Ross said. “It’s going to be pretty much like this series.” In the next round, the Giants will be facing a much more potent lineup than anything the Braves could muster. They didn’t have the strongest lineup to begin with and came into the playoffs without two of the their best hitters, Chipper Jones and Martin Prado, both out with season-ending injuries. Atlanta hit .175 as a team and scored only nine runs in the four games. “Our pitching, I can’t say enough about,” Ross said. “We scored only a handful of runs and ended up winning the series in four games. It just goes to show how valuable they are.” Bumgarner did his part, allowing only six hits and two runs. He wound up getting the win as the Giants scored twice in the top half of the seventh, again aided by some shaky Atlanta defense. This time, it wasn’t Brooks Conrad — the guy who made three errors in Game 3 didn’t start. Instead, shortstop Alex Gonzalez made two errors, the second of them a high throw that just barely pulled Infante off the bag on an attempted force at second. That miscue allowed Ross to get to the plate, and he came through with a single to left just out of Gonzalez’s reach to bring home the go-ahead run. Pat Burrell also attempted to score, but he was thrown out at the plate to end the inning. Not to worry. A 3-2 lead was good enough for the Giants bullpen. Santiago Casilla worked 1 2-3 innings, Javier Lopez struck out Jason Heyward to end the eighth and Wilson earned his second save in as many nights. “This series had everything,” Giants manager Bruce Bochy said. “Just the intensity and excitement of the series, it had to be thrilling for the fans. There was never an easy moment for Bobby or myself, because these games could have gone either way.” Atlanta starter Derek Lowe pitched no-hit ball into the sixth inning, and still it wasn’t enough. The Braves have yet to win at Turner Field with a series on the line, losing for the eighth straight time in that situation since the Ted opened to baseball in 1997. Cox won’t get a chance to end that streak, calling it a career at age 69. He heads for the rocking chair as the fourth-winningest manager in baseball history (2,504 regular-season victories) but one major shortcoming on a record that will surely be good enough for the Hall of Fame. In 16 trips to the playoffs — one with Toronto, 15 with the Braves — Cox’s teams captured only one World Series title, way back in 1995. A Braves fan held up a sign pleading for the team to “Win It For Bobby,” but Ross and the Giants were in no mood for sentimentality. They were ready to party. “I really didn’t know what to expect,” Lincecum said. “Guys tell you, but you don’t know until it happens. A lot of swearing, a lot of screaming, a lot of alcohol.” Ross, who was acquired on waivers from Florida in late August, has already paid big dividends in October. With one out in the sixth, he struck for San Francisco’s first hit of the game — a liner that barely cleared the left-field wall. Then, after Brian McCann put the Braves back in front with a homer of his own, Ross came through with the go-ahead hit. Lowe — rocking back and forth, muttering to himself and sweating profusely on an unseasonably warm night — did all he could on three days’ rest. It wasn’t enough to extend Cox’s career. “I’m proud of this team,” the now-retired manager said, his eyes watering. “They played their hearts out and I’ll miss them.” | Mid | [
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When purchasing tickets to, or registering for this event, we provide the information entered to the event organiser so they can manage the event. If you do not want the event organiser to have this information, please do not proceed with your purchase or registration. Please review our Privacy Policy for more information. Event Details Chocolate Making really is the simplest of tasks, we invite everyone to have a go at creating their own beautiful chocolates while having a chocolate treat or a coffee in our Cocoa House. Be inspired by our chocolatiers and have a go creating your own chocolate treat to show off, share or just enjoy. Choose from a selection of toppings to create your own chocolate lollipop exactly how you want it to be. You will work with professionally tempered milk chocolate with 35% cocoa solid to create your chocolate lollipop. You will need to allow it to set before wrapping it up to take it home. Please join us any time between 10am and 4pm daily. Please note that you can drop in at any time and make your chocolate treat while enjoying a drink in our Cocoa House cafe, on some occasions there may be a short wait for a table if the cafe is busy. Our Chocolate Lollipop activity is available to purchase as a gift certificate, if you would like to make this purchase as a gift please select a date from those available and specify when booking that this is a "gift purchase". We will request further information during the booking process to be able to send a gift certificate, valid for 12 months, to the recipient. Group bookings: We are able to cater for large groups of chocolate makers by arrangement, please contact us on 01904 675787 if you have a group of 8 or more participants who would like to create something special. Please be aware that this is short chocolate making treat, for a special workshop ideal for your group please contact us so we can discuss what we can offer you. Special Dietary Requirements: At York Cocoa House we work with the initial ingredients to ensure that the only things that go in our products are things that really need to be in there. Chocolate doesn't have to be sweet or creamy or contain any wheat, gluten or nuts if we don't want it to. We're determined to help chocolate lovers find the perfect chocolate for them, be it sugar free, dairy free, high cocoa content, nut free, gluten free or however you love it, please just ask. For further information please see our guidance for Special Dietary Requirements. York Cocoa House 3 Blake St YO1 8QJ York United Kingdom Tuesday, 27 December 2016 from 10:00 to 17:00 (GMT) Organiser York Cocoa House At York Cocoa House, we love all things chocolate - eating, making, cooking and most importantly sharing. Join us to discover the wonderful world of chocolate in the heart of York, the chocolate city. We have a whole range of exciting chocolate activities that you can join us to indulge in and learn a bit more about chocolate, the food of the gods. Visit our Cocoa House Chocolate Cafe and try our Afternoon Chocolate Tea or just drop in at our cocoa house for our own specially made York Cocoa House hot chocolate and explore chocolate's history in York. We are often making chocolates in the shop. Feel welcome to come and watch or ask us if you can test what we're making. | Mid | [
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mitakuye oyasin I Stand with Standing Rock: Water is Life WE DO HAVE POWER “We have power… Our power isn’t in a political system, or a religious system, or in an economic system, or in a military system; those are authoritarian systems… they have power, but it’s not reality. The power of our intelligence, individually or collectively, is the power. This is the power that any industrial ruling class truly fears: Clear coherent human beings.” -John Trudell 2016 anthology happy visits A case before a federal appeals court last week could upend an historic adoption law meant to combat centuries of brutal discrimination against American Indians and keep their children with families and tribal communities. For the first time, a few states have sued to overturn the federal Indian Child Welfare Act, which Congress enacted in 1978 as an antidote to entrenched policies of uprooting Native children and assimilating them into mainstream white culture. Now, in a country roiled by debates over race and racial identity, there’s a chance the 41-year-old law could be overturned by the U.S. 5th Circuit Court of Appeals, considered the country’s most conservative court. (The law applies to federally recognized tribes.) “This is about attacking Indian law and Indian sovereignty,” said Chrissi Nimmo, deputy attorney general for the Cherokee Nation. “This is just the first step.” The Cherokee, Navajo, Oneida and Quinault Indian Nations, as well as the Morongo Band of Mission Indians, asked to be included as defendants in the lawsuit. We didn’t cross the border, the border crossed us.” That’s the message from communities who live with the troubled legacy of colonialism today—the descendants of Native peoples who have survived in defiance of the national divides that strafe their lands and run counter to their cultural inheritance. Such a move, (THE WALL) according to the resolution, would threaten territorial rights, “further divide historic tribal lands and communities,” “militarize the lands on the southern boundary,” and “disturb or destroy tribal archeological, sacred sites, and human remains.” For her 16th birthday, Maddy Fernands asked her parents for an unusual gift: to switch the family to wind power. She didn’t want an iPhone, new clothes or — banish the thought — a car. Cars and trucks account for about a fifth of greenhouse gas emissions, and a significant amount of Fernands’s climate anxiety. “Sometimes we’ll be stuck in traffic and I’ll look outside and watch the exhaust coming out of the car in front of me and I’ll freak out,” she told me. “I feel so powerless to stop it.” Fernands has been struggling with that sense of helplessness since she first became keyed into the accelerating timetable of climate change in seventh grade. “It seemed like the end of the world,” she said. “But the apocalyptic message wasn’t being broadcast. Nobody was taking correct action to put us on a path away from climate catastrophe.” Because her parents and teachers didn’t seem to share her urgency, Fernands decided that she herself would have to sound the alarm over climate. Climate change is causing mental anguish in people of all ages, according to Lise Van Susteren, a psychiatrist and member of the Climate Psychiatry Alliance. “When you’re hearing day in and day out that we’ve got 12 years, we’ve got 11 years, the oceans are collapsing, fires are burning, air quality is terrible, wear a mask, the anxiety is inescapable,” said Van Susteren. book review: Truly prolific writer poet community organizer J Glenn’s visionary fiction novel Wayfarers – Where No One Is an Outcast is about an interesting mix of homeless people who want to help other homeless people. Do we need it? Timely? Absolutely. Right to the end of his fiction novel, suspense abounds. In real life: There are always two groups of people: the Have’s and the Have Not’s. Can there be a Happy Ending? The brilliant idea from Wayfarers story leads the author to buy land in Oklahoma for this very purpose: a farm where the homeless can resettle in 2019. I interviewed the author in Jan. 2015. J Glenn is an elder, a man of vision and great wisdom. He is a good friend and a true inspiration. He has shared his ideas on this blog HERE HERE FORK IN THE ROAD WEWOKA, OKLAHOMA — He arrived at this latest fork in the road pretty late. Glenn Evans is 88 now but excited about what he calls his last hurrah, an idea he would like to try out on this plot of land. A visitor asks, “Why in the world would you want to leave Washington State, one of the gardens spots of the U.S. to here?” Evans makes a circle with his finger beside his head and chuckles, “I’m a little nuts.” He grew up on a farm near Wewoka where most of his family’s food needs were met with a big garden. Glenn’s family moved to town though. On a walk through tall weeds on his new land, his guest asks, “Are we bushwhacking your trail?” Evans says, “No we’re just starting one. We’re pioneers!” He went off to school and chased success as a stock broker. He left that and turned to a career in writing. Several books in he wrote a novel called ‘Wayfarers‘ about a group of homeless people who want to help other homeless people. His thoughts while writing, “I want to do something for people. Create a place where they can live together as a family.” Evans started walking around and thinking what worked in fiction might work in real life. “I wanted to make my first place right here in Oklahoma,” he says. So here’s his new idea. Invite people, maybe homeless, he’s not sure, to open up this acreage to folks who want to grow their own food, who want to live off their gardens like his family did. “Food and shelter, and you’re part of a family,” he suggests. They use no till farming methods, plant some fruit trees, and live in underground houses to stay cool in the summer, warm in winter, and safe in the spring. Of living underground, Evans says, “It’s good for tornadoes.” It took him a couple of hours to walk through the brush and get a good gauge on the property. The only road on it leads to a pump jack, but J. Glenn sees a successful future here. “Is the land good,” asks his visitor? “Oh. I think it’s good and rich,” he responds. Look at the soil. It’s had years of composting.” Call him a visionary, or call him a crazy old man. Glenn Evans just needs a few more crazy people like him to unplug and dig in, to make this fork in the road a little bit wider. From Seattle and the Pacific Northwest, this picaresque novel takes on the issues of homelessness, big city corruption, and corporate greed. An engaging, rollicking tale of those who are mostly down on their luck and chafe under the rules and regulations imposed by those in authority. They were small in numbers, inexperienced, and some of them uneducated but they made up for it in a passionate belief in themselves. Wayfarers is an adventure story about a homeless half Cherokee who sets out to do something for the homeless with the help of such characters as a prostitute, a disbarred lawyer, a cuckolded preacher turned prospector, ex-CIA man, a veteran turned warrior for the good and a small Indian tribe. The two main protagonists, RB (Chief) and Warrior, each has his own way to bring justice into the world: one that allows the Native American culture to nourish and restore health to the planet. The other protagonist, Warrior, has a strong sense of justice laced with a mission to punish the evil-doers. Against this backdrop are the greedy power-brokers hell-bent on imposing their views on society. What will be the final outcome and whose philosophy will be the winner? A regenerative culture vs the competitive materialistic one? The wayfarers seek to provide alternatives to living on the street or to incarceration. There is a wisdom of indigenous peoples that we can use to help put our post-industrial society on a more ecological basis. Laced with the honesty of Steinbeck – both religious and profane, dangerous and divine – this pot boiler keeps rolling to the finish line. This exquisite little book is actually two books in one – both thoughtful compilations of original poems, prose snapshots, memes, photos and “creative nonfiction,” all beautifully laid out on the page. Mental Midgets contains a moving tribute to Native American musician, poet, philosopher and activities John Trudell, who died in 2015. General themes covered in both books are colonization, the survival and resistance of indigenous people and the attitude of hopeful resistance all of us need to survive the barbarity and insanity of advanced industrial capitalism. Part of the reason for why McCarthy’s scandal got little or no attention is because there isn’t an unspooled Democratic leader firing off out horrendously racist “Pocahontas” and Trail of Tears tweets as Trump keeps doing about Warren. (The troll-in-chief has to troll.) Consequently, the television news media doesn’t pay any attention to the McCarthy story, which means voters don’t pay attention either. And when reporters notice that voters don’t care, the conventional wisdom calcifies. The circle of crapola goes the other way, too: Trump says “Pocahontas” is a fraud; the news media picks up the tweets and runs them without debunking them; voter outrage grows; the Beltway reporters note the outrage and then tell Chuck Todd on “Meet the Press” that it’s a disqualifying scandal for Warren because voters are pissed. But why are they pissed, if they actually are? Because the press told them to be. See? And Trump wonders why Democrats are so angry. As if that weren’t objectionable enough, there’s never any effort to put the Native American story in the proper context. How does Warren’s thing stack up to other scandals? Is this as bad or worse than Kevin McCarthy’s brother-in-law receiving millions in taxpayer funds because he claimed membership in a disputed tribe? Should we care about this as much as, say, the fact that literally every major organization linked to the Trump family is under state and federal investigation for rampant fraud? Context be damned in the face of publishing more screamer headlines about — say it with me — Democrats in disarray. “The alarming number of missing and murdered indigenous women and girls continues to grow,” the senator says Warren spoke at the National Indian Women’s “Supporting Each Other” lunch, where she introduced Cheryl Andrews-Maltais, the chairwoman of the Wampanoag Tribe of Gay Head Aquinnah in Massachusetts, HuffPost first reported. The luncheon took place during an annual meeting of the National Congress of American Indians. In her speech, Warren praised Native American women, specifically Reps. Deb Haaland (D-N.M.) and Sharice Davids (D-Kan.) — the first two Native women elected to Congress. The progressive lawmaker, who reportedly received a standing ovation from tribal leaders and other Native attendees as she approached the stage, detailed several legislative priorities related to the Native American community. “The alarming number of missing and murdered indigenous women and girls (#MMIWG) continues to grow,” she said, according to The Daily Beast. “But Congress failed to pass legislation to address this epidemic.” “Every day, there’s a racist tweet, a hateful tweet – something really dark and ugly,” Warren said of Trump. “And what are we, as candidates, as activists, the press, going to do about it? Are we going to let him use those to divide us?” The curators are a group of young, energetic curators from distinct backgrounds and points of views. The artistic director Neville Wakefield is an art star known for his work in performance, site installations, and partnerships with fashion brands such as Supreme, Nike, and Calvin Klein. The biennial’s executive director, Jenny Gil, who is from Spain, formerly worked for Faena. The curator Amanda Hunt recently worked at the Studio Museum before joining MOCA. The LA-based writer and curator Matthew Schum was informed by his doctoral research on site-specific happenings, including the Istanbul Biennial. They have selected a broad group of artists of diverse nationalities, ages, and practices, supporting the conception, construction, and installation of each of the works. A budget of $25,000 or (much) more per work was offered by donors such as the Coachella Music Festival (which donated over $100,000) and electric car company Evelozcity. On 55 miles spread between the Wildland Park in the northwest and the Salton Sea in the southeast, the installations take the visitor on a road trip on a circuitous path of highways, windmill farms, gas stations, hot spring spas, residential compounds, and Modernist homes. The works will be up until April 21 and are accessible free of charge, alongside a series of performances and events. Land Art is no longer a romantic and heroic gesture in the vastness of nature. It is by essence a political act. History’s largest Native American art fraud case will come through the courts this year after multiple family businesses manufactured, imported, and falsely distributed Native American-style jewelry as genuine between 2010 and 2015. The trade value reached nearly $12 million across 300 shipments in five years — now, five men and two businesses are charged with violating the Indian Arts and Crafts Act, importation by false or fraudulent practice, and failure to mark goods with their country of origin as required by customs law. Congress passed the Indian Arts and Crafts Act (IACA) of 1990, to include the importation of knock-offs which undercut Native American economies and cultural heritage. A poetic short by Detroit-based director Keenan Wetzel, “Yellowtail” tells the story of a young Native American cowboy (Stephen Yellowtail) searching for purpose amidst a chaotic lifestyle. (previously featured here). Shot in Wyoming and the Crow Reservation in Montana, “Yellowtail” tells the story of a young Native American cowboy (Stephen Yellowtail) searching for purpose as his chaotic lifestyle begins In the News The Navajo Nation and Utah Governor signed an inter-governmental agreement Monday, Feb. 4, 2019, to strengthen and further protect the Indian Child Welfare Act for the benefit of Navajo children in the State of Utah. Nation President Jonathan Nez and Vice President Myron Lizer met with Governor Gary Herbert to make it official at the Utah State Capitol during the annual American Indian Caucus Day. Let’s take a quick look at the erratic history of federal Indian policy. In the early republic, the federal government made treaties of friendship with Indian tribes east of the Mississippi. In the 1830s, it stopped feeling friendly and removed the eastern Indians to the West. It set up reservations for eastern and western tribes and solemnly promised in treaties that the land would be theirs forever. In 1871, Congress decided there would be no more treaties, because Indian nations were no longer sovereigns; the courts soon confirmed that Congress could void any treaty without the consent of the tribes that had signed it. Next, from the 1880s until the 1930s, came the “allotment era.” The government decided to break up the reservations and “allot” much of the land to individuals, who could sell them. By the 1930s tribes had lost 60 percent of their previous land base. The New Deal was a brief respite: Allotment ended and tribes were allowed to re-form their governments. Then in 1953 came the “termination era,” when Congress decided that the federal government would no longer provide services to tribes, or deal with their governments. It sold off some tribes’ reservation lands and proclaimed that those tribes no longer existed. University College London researchers estimate that settlers killed 56 million indigenous people, causing farmland to be reforested. That increase in vegetation resulted in a massive decrease in carbon dioxide in the atmosphere. But they conceal another side of Columbus: the exploitation and repression of Native Americans, said the Rev. John Jenkins, president of Notre Dame. It is a “darker side of this story, a side we must acknowledge,” Jenkins said in a letter Sunday. In December 2018, the Trump administration plotted to gut SNAP, the food assistance program more than 40 million Americans rely on to feed themselves. (I have friends and relatives on SNAP, what used to be food stamps). This attack on the poor would impose oppressive work requirements that will have a devastating impact on our nation’s most vulnerable and the “food insecure.” This rule will drive 755,000 poor folks deeper into poverty across the country over the next three years. It’s a cruel and cynical attempt to chip away at our social safety net by defining who is and who isn’t suffering in our nation. Read about the Poor People’s Campaign. Food insecurity is very real and a war on the poor. And when the climate fails and disaster hits, what new countries start a new land grab? Will they hit Third World Countries? Indian Country? Will they take children to accomplish this again? History repeats itself over and over until we get it right…and so we are entering a dangerous new age of food insecurity… and climate change. If I were in charge, I’d have two priorities: ending poverty and improving the existing infrastructure. “I called the album Blue Indians because there is a kind of spiritual and cultural genocide perpetrated on everyone that is poor in this country,” Trudell said. “The advance of technology has put all of us on a kind of reservation. These are the people who can’t educate their children, or afford health care. They’ve been robbed of life, which is what happened to Native people, so in that context, we’re all Indians.” Guðrún Emilsdóttir, adopted shortly after birth, was 28 before she tracked down her birth mother. Her birth mother gave Emilsdottir her birth certificate, which named her father, Henry Linwood Jackson. “My nephew started looking for Henry,” she said. Eventually, he contacted Native American genealogist Karen Vigneault, a member of the Iipay Nation of Santa Ysabel in California who was profiled in an earlier VOA story. On Vigneault’s advice, Emilsdottir took a DNA blood test; they uploaded the results onto an online database and waited. (PHOTO: Iceland covered the story too) (Karen Vigneault, an enrolled tribal member of the Iipay Nation of Santa Ysabel and college and tribal librarian, has a face tattoo.) Emilsdottir has returned to Iceland but is planning to return to Oklahoma in July 2019 for the “Encampment,” a pow wow the Otoe-Missouria tribe has held annually for more than 130 years. It’s an occasion for the tribe to sing, drum, dance and remember their history and traditions. And celebrate family, lost and found. The reunion happened because of the tireless methodical work of librarian and tribal genealogist Karen Vigneault; she and I have worked together since 2013. I learned yesterday that Karen has passed away in San Diego at her home. She made miracles and reunions for adoptees, like these sisters. It is impossible to put into words the impact she had on me and the lives of many adoptees she helped. She worked to find adoption records, tribal histories, family genealogy and find relatives that adoptees could contact and meet. This loss is personal and devastating. Not just to me but to readers of this blog who are still searching and hoping and waiting and wanting to find their families. Karen traveled to Iceland late last year to meet Guðrún and the Iceland media covered it. Her wish was to reunite Guðrún with her tribe and relatives. She succeeded. Just half of Wolf Point’s Native students graduate from high school, compared with about three-quarters of their white peers. In June 2017, the Tribal Executive Board of Fort Peck filed a civil rights complaint with the U.S. Department of Education’s Office for Civil Rights requesting a federal investigation into its contention that the Wolf Point school system discriminates against Native students. In her essay “Alone in Company,” Chelsea Bayouth reflects on the role of an artist at the end of 2018: “For me, it is to fear that every word or image is a window into public, political, and social tumult. It means you have to be more vulnerable than you or anyone in times previous has ever been…. Social capital is the currency, and if you have none you are poor. ” **** Royal statues from the Palaces of Abomey in Benin, displayed at the Quai Branly Museum in Paris; they are among the works slated to be returned to Benin as soon as possible (photo by Jean-Pierre Dalbéra via Flickr) The Ivory Coast is demanding that France return 148 works once looted from the country. The Ivory Coast’s culture minister, Maurice Bandaman, confirmed that a list of works were sent to France and are set to be returned in 2019. Bandaman also told Agence-France Presse, “At least 50 museums around the world have Ivorian works, and this does not include private collection,” indicating that France is not the only country with looted works. [Agence France-Presse] A new work by Banksy has appeared at the back of a car garage in Port Talbot, Wales last week. Since then, crowds have gathered at the scene, with local authorities having to manage and organize the groups of people. Banksy claimed responsibility for the work on his website and Instagram. The garage is owned by Ivan Lewis, a local steelworker. “I’ve never experienced anything like this,” said Lewis. “My phone is ringing, on my house phone there’s 1,000 messages on it.” [Art Daily] ** Shan Goshorn, “a Cherokee artist and activist known for her contemporary approach to traditional basket-weaving,” died of cancer at the age of 61. [Tulsa World] * Under a cloud of scandal… the toxic Interior Secretary Ryan Zinke is gone (fired) (top photo) Can we call it a year now? 2017 and 2018 wore me out. Cancer didn’t help but I feel woke enough. Indigenous people and supporters gathered despite sub-zero wind chills for the 49th National Day of Mourning at Plymouth, Mass. The undaunted crowd included Indigenous peoples whom the pilgrims menaced and murdered — Nipmuc; Mashpee, Aquinnah and other bands of the Wampanoag; Narragansett; Massachusett; Pequot and other Indigenous nations… The commemoration known as Plymouth 400 will feature events throughout 2020, including a maritime salute in Plymouth Harbor in June, an embarkation festival in September, and a week of ceremonies around Thanksgiving. We are not supposed to know (continued) After the residents of Malaga were pushed out, the state bought the land for $471, according to Maine Coast Heritage Trust, and ordered the rest of the residents to leave by July 1. In 1913, the state sold the land to Everard A. Wilson, a friend of the doctor who had been the chair of a committee Plaisted had established to investigate the allegedly appalling conditions on Malaga. Malaga was for many years in private hands, but remained undeveloped. The hotel that had been planned for Bear Island, which Hamilton said was a key incentive for pushing the Malaga residents off the island, was never built. A subsequent Associated Press article in The Los Angeles Times revealed that Ms. Thompson was not of European descent — as had been commonly assumed — but “a full-blooded Cherokee Indian” from Oklahoma. That detail, Ms. Meister said, raises the compelling question of whether “Migrant Mother” would have resonated so widely if viewers knew the subjects were Native American. (another one of those “shake your head” stories, right? **** ☀️ I write something every. single. day.☀️ By LT Is time speeding up? I am still trying to figure out to talk about the twin books: Mental Midgets | Musqonocihte and why one book became two and how they happened so fast. (I have to thank my friend MariJo for telling me what I felt about urgency was to be trusted.) It’s a short book – 91 pages – but it feels MUCH longer. I do think of this year 02018 as The Year I Had Cancer – this changed me mentally. Was it five years ago when I started the Midgets book. I used to joke and say it might get done this century. Why? My goofy utter distrust, of course. Many of you are experiencing what I call wavy brain too. We don’t think about the future as much as before… and why is that? Read about the Long Now Foundation from earlier this year. Trump and electronics are both a BIGLY reason! Back then I kept the book title under wraps. Mental Midgets, what does it mean? It’s absurd. It’s maybe kinda funny. It’s not about small people. But it is about our minds, the constant chaos, the news, Trump, cell phones, social media, and how it seems to me, at least, our brain capacity shrinks when memories go small. And then there is (hi)story to consider. Here is a one sentence (short) book description: This TWIN book is a collection of factoids, philosophy, quips, questions, code, quotes, photos, thought bombs, creative non-fiction, Native American history and prose. And it’s short. Musqonichte translates Blue Sky. Sending you all a big thanks for reading this news roundup and Happy Turkey “Big Food” Day tomorrow… Lara/Trace An Exhibition Critically Explores the History of Missionaries in Hawai’i WILLIAMSTOWN, Mass. — In August 1806, five students on the campus of Williams College took refuge from a sudden thunderstorm beside a haystack and vowed to commit themselves to spreading the Gospel around the world. This is Ground Zero of the American overseas missionary movement. For many people, this moment marked the start of an outpouring of generosity and benevolence that saved souls and brought distant lands into the modern world. Only recently has another narrative been recognized — one of shameless spiritual imperialism that trampled native cultures and eventually devolved into explicit political and economic oppression. This slideshow requires JavaScript. The unexpectedly deep connection between the college in Williamstown and the Pacific islands, 5,000 miles away, is outlined with an extensive timeline along a wall, which highlights what was happening in each place. It mentions figures such as Sanford B. Dole, the son of missionaries who came to Williams in the 1860s, where he and other missionary descendants called themselves “the Cannibals,” and were active in the Lyceum. Dole and two others from that group would help draft the “Bayonet Constitution” of 1887, which accelerated the process of undermining native Hawaiian leadership. When the monarchy was overthrown in 1893, Dole would serve as the Republic’s first president, until completing the handover to American power a few years later. How can that be? In 1832, President Andrew Jackson pushed through the policy of “removal” of Indian nations from the eastern U.S., which destroyed the historic land base of the “civilized tribes.” He promised the tribes new land in the West to be theirs “as long as the grass grows or the water runs, in peace and plenty.” After the Trail of Tears, the U.S. signed a treaty that “solemnly guarantied” the new reservation lands in what is now Oklahoma. Many tribes elsewhere have found to their regret that Congress is permitted to decide that the grass ain’t growing any more. It can abrogate some or all treaty obligations—and even “terminate” a tribe altogether. But case law says there is a “clear statement” rule: If Congress wants to end a reservation, it has to say so. U.S. Senator Lisa Murkowski (R-AK) highlighted the report in a press event in Washington, DC, this week where she talked about the importance of addressing the MMIWG epidemic. Murkowski was joined by U.S. senators Heidi Heitkamp (D-ND), Patty Murray (D-WA), Maria Cantwell (D-WA), Jon Tester (D-MT), Representative Gwen Moore (D-WI 4th District), and Juana Majel-Dixon (Pauma Band of Mission Indians), Executive Board Member and Recording Secretary of the National Congress of American Indians (NCAI). The UIHI report identified the state of Alaska as the fourth-leading state for number of cases of MMIWG. Also, in the top ten states are New Mexico, Washington, Arizona, Montana, California, Nebraska, Utah, Minnesota and Oklahoma. Hospice of Failed Utopias… Uruguayan Torture Series (1983–1984) is a direct reference to military authoritarianism in Latin America. Hospice of Failed Utopias Madrid – At the Museo Reina Sofía, the artist Luis Camnitzer has piled up a grid of 80 blocks, approximately 12 by 12 inches each, and wrapped them in brown gauze. Imprinted with the word “LEFTOVER,” followed by a Roman number, each block appears to have been shot, dripping fake, plastic blood on the museum’s floor. The piece, “Leftovers” (1970), is an homage to those of Camnitzer’s generation who died in the hands of the Uruguayan repressive state. As an essayist, art critic, curator, teacher, lecturer and a creator of objects, actions and musical compositions, Luis Camnitzer’s multi-faceted work spans nearly 60 years… The work Failed Utopias gives the exhibition its name, at the express wish of the artist. Chiming with his usual irony, Camnitzer alludes to the ‘dark’ history of the Sabatini Building as a hospital and as a place for ‘lunatics, or the insane’. The retrospective also constitutes a time frame of Camnitzer’s utopia, which he defines as “a process through which one seeks perfection, where perfection, like a mirage, constantly grows distant at the same speed one believes oneself to be nearing it. Something similar to the revolution in the revolution”. Born in Lübeck (Germany) and raised in Uruguay, Luis Camnitzer moved to New York in the 1960s, where he focused on his art, essays and teaching work. He is currently professor emeritus at the State University of New York. Camnitzer regards himself as a Latin American artist exiled in the contemporary art capital, and is unquestionably a key figure in the development of twentieth-century Conceptualism. Hospice of Failed Utopias, the title of Camnitzer’s retrospective at the Reina Sofía, features 100 of his works produced since the 1960s. Camnitzer’s newest piece, “About War” (2016–2018), considers the influence of military strategy in contemporary mappings of the world. “About War” juxtaposes quotes from Carl von Clausewitz’s military strategy treaty On War with Google maps locations of US military bases in Latin America. Zaya cites from Camnitzer’s emails: “We are now returning to the most reactionary kind of nationalist fragmentation, […] all of this within the context of a kind of neo-feudalism, where the weapon industry is provoking new military clashes.” “And Our Mothers Cried” vividly brings to life the Indian boarding school era of the late 19th and early 20th centuries. For several generations of Native American children, including some Chickasaws, attending boarding school meant separation from their families and indoctrination into a culture that wasn’t their own. The schools, which were guided by the infamous slogan, “Kill the Indian. Save the Man,” prohibited most students from speaking their own language and emphasized labor-intensive trades that would assimilate them into white culture through military-type institutions. The documentary presents a stark contrast between these schools and schools established and operated by the Chickasaw Nation, which were designed to prepare Chickasaw children to compete in a rapidly changing world. “And Our Mothers Cried” presents compelling stories from some of the Chickasaw elders who lived through the boarding school era. Their experiences weave a complex story of sorrow and survival, but also one of hope and resilience from a time when tribal governments and culture were under attack. On June 15, 2017, at its Mid‐Year Conference in Connecticut, the National Congress of American Indians (NCAI) adopted a resolution, sponsored by the Chickasaw Nation, encouraging American Indian and Alaska Native Tribal Nations, families, and descendants to provide information on children who never returned home from Indian Boarding Schools. The information will be used for a submission to the United Nations (UN) Working Group on Enforced and Involuntary Disappearances (UNWGEID). This UN submission will be jointly filed by the National Native American Boarding School Healing Coalition (NABS), the International Indian Treaty Council (IITC), and the Native American Rights Fund (NARF). The submission will call on the United States to provide a full accounting of the children taken into government custody under the U.S. Indian Boarding School Policy whose fate and whereabouts remain unknown. NCAI represents 250 American Indian and Alaska Native Tribes. The Unassigned Lands In the 1860s and 1870s, white settlers from the areas around Indian Territory — like Kansas and Texas — started to realize that there was vast piece of land in the middle of the United States that wasn’t claimed by anyone (ah, what?). They started agitating to to be allowed to seize this land for free. These white settlers even began a series of illegal raids into the territory, sneaking into Indian Territory at night to get to that little center portion of the Unassigned Lands. Couch and his men had brought surveying equipment — and they quickly began laying out streets and lots as they had planned them in the months leading up to the Land Run. In the days following Oklahoma City’s rapid settlement, town leaders would have to reckon with all the cheating that had happened during the Land Run. Who cheated and who didn’t? Who deserve to keep their land and who didn’t? When I heard the drum at this powwow in Wisconsin, when I was 12, the sky opened up and my heart fell in. I was adopted out to strangers but I would find my family, no matter what. (My memoir is now retired. I will be rewriting soon.) BY LT What? Back so soon with breaking news? Yep. First, I want to thank my friend and blogger KC for asking me to think about and share my thoughts on what it means to have Indigenous ancestry and the recent headlines about Elizabeth Warren. Next, I defend Sen. Warren’s right to claim her ancestry. It’s hers! Heck, many Americans do have some American Indian ancestry, too. But what you do with it is what truly matters. We are all mixed, one way or the other. American, so heavily colonized, is very populated with mixed people. We have (hi)storians to blame for not explaining much about this stark truth and reality. For me personally I was not raised in a tribal community setting, though I had many Native people around me when I was growing up. Being adopted out, I struggled until my 30s with identity and isolation, but no longer. I met my birth father and did a paternity DNA test with him when I was 38. The history he shared with me, that was what I needed, at that time. But words and blood tests DO NOT make me who I am or the direction of my life’s work. My Oglala Lakota relatives made sure of that. They were in my life years prior to my finding my father who is mixed Shawnee-Cherokee-Delaware-Euro). What is required of us: Once you attend ceremony, once you pray in your language, once you show humility to elders, and once you work for them, and when you learn it’s not “me” but “we” – it is then you are made a relative and accepted as family. Then you are in tribal community (which is American Indian tradition on Turtle Island). It may take many years, because it should. As the following story by Nick Estes says, “Half a century ago, the Standing Rock Dakota scholar Vine Deloria Jr. wrote, “Whites claiming Indian blood tend to reinforce mythical beliefs about Indians.” Falsely claiming Native American identity is a white American tradition, with a deeply racist past. – Nick Estes Warren is not living her life as a member of any tribal community, yet like so many, she seems to romanticize the idea of her blood being Indian. She was raised with her family in Oklahoma, with her history, but she was not enrolled with the Cherokee Nation, who determines their citizenship based on Dawes Rolls, not DNA. If the Cherokee tribe wishes to change that, and enroll her, it’s completely up to them. (She’ll have years of unlearning and good history lessons ahead.) To my knowledge, what Warren did with her “ancestry” all these years, was she helped herself. To my knowledge, she did not assist any tribal nation or community, and in fact, she has not even helped the tribes struggling right here in Massachusetts! What we are fighting for in this century, like Standing Rock, federal recognition, sovereignty, treaty rights, water rights, protecting Bear’s Ears, ending destruction by mining, pipelines, poverty, all of that – where is she? This is a new hashtag campaign: #NativeTruth #WeAreStillHere If Elizabeth was in her community, she’d know this: Blood quantum is an invention of the governments to widdle us down to “not enough Indian.” (Wiping us out on paper. Gone, erased.) I actually know many lost Native adoptees who use the DNA test to get their family name, and slowly worked their way back to their tribal families. Some are back on the rez, while others join their urban Indian communities. (I do not recommend or trust the DNA testings or the data they collect and sell. Those TV ads are false and misleading. Very few Indians will submit to giving DNA though some scientists took it without their consent.) When is a DNA test useful? My adoptee friend Rhonda did a DNA test with an uncle (her birth father’s brother) to determine if she was a family member, and she was – then she was enrolled in her tribal nation. DNA can connect you with a living tribal member, if you were adopted out, or fostered. That is very very helpful. So, Sen. Warren, it’s not the amount of blood. DNA doesn’t make you Indian. If you belong to a community (urban or reservation), that makes you a member of that tribal community. Native Americans are almost completely erased from pop culture, news and K-12 education. This invisibility–more than any other factor–undermines public support for Native American rights. Join our #WeAreStillHere tweet storm. Reclaiming #NativeTruth: https://t.co/vzL4SuF4P6 If you do have Indigenous blood, if it is loud, it won’t leave you alone. If this speaks to you, then find and join an urban or reservation community and work for them and work with them, and think a new way: “we” not me. And ask them what you can do and please do what they ask respectfully. The exhibition Community and Continuity: Native American Art of New York is culled from the New York State Museum’s collection of contemporary Native American art. NYSM is known for its historical and archeological Indigenous objects, which number in the millions and range in date from 13,000 years ago to the early 20th century. But in 1996, the museum began acquiring works by living Algonquin and Haudenosaunee (Iroquois) artists to celebrate the continuing vibrancy of these communities. This is the story of the courageous all-female Apache 8 firefighting unit which has protected their reservation and responded to wildfires around the nation for 30 years. This group, which recently became co-ed, earned the reputation of being fierce, loyal and dependable–and tougher than their male colleagues.Despite facing gender stereotypes and the problems that come with life on the impoverished reservation, the women became known as some of the country’s most elite firefighters. The film focuses on four women from different generations of Apache 8 crewmembers who speak tenderly and often humorously of hardship, loss, family, community and pride in being a firefighter.Official Selection at the American Indian Film Festival. Thousands of Canada’s indigenous children died in church-run boarding schools Armed with everything from school attendance records to drones, researchers across Canada are racing to shed light on a bleak part of the country’s history: How many indigenous children died at residential schools, and where are their unmarked graves? From 1883 to 1998, nearly 150,000 indigenous children were forcibly separated from their families and sent to the government-funded, church-run boarding schools in an attempt to assimilate them. Once there, they were frequently neglected and abused. What happened at the schools was akin to “cultural genocide,” concluded a 2015 report from Canada’s Truth and Reconciliation Commission. It also found that at least 3,200 students died at residential schools over those 115 years — a much higher rate than for students elsewhere in Canada — though the commission contended that the number was probably much higher and merited further investigation. The religious organizations that operated the schools — the Anglican Church of Canada, Presbyterian Church in Canada, United Church of Canada, Jesuits of English Canada and some Catholic groups — in 2015 expressed regret for the “well-documented” abuses. The Catholic Church has never offered an official apology, something that Trudeau and others have repeatedly called for. Most journalists also said we didn’t bother to cover Indigenous peoples because there was no journalistic payoff. We, reporters, preferred to do stories to improve situations and conditions, by pointing out things that didn’t work properly. We looked for bad guys, stories about corruption or inept business owners, government administrators, politicians, cops, for example. Yet similar stories about Indigenous communities never went anywhere. Things never changed. Also, by telling these stories, we faced accusations of concentrating on the negative. (See comment above about racism.) | Mid | [
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