broad_id
string | depmap_id
string | ccle_name
string | screen_id
string | upper_limit
int64 | lower_limit
float64 | slope
float64 | r2
float64 | auc
float64 | ec50
float64 | ic50
float64 | name
string | moa
string | target
string | disease.area
string | indication
string | smiles
string | phase
string | passed_str_profiling
bool | row_name
string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BRD-K47832606-001-30-1 | ACH-000592 | TM31_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.204918 | 5.749631 | 0.723898 | 0.422942 | 0.008734 | 0.009573 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000592 |
BRD-K47832606-001-30-1 | ACH-000368 | SNU1105_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.04548 | 1.07715 | 0.76943 | 0.486676 | 0.053925 | 0.058917 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000368 |
BRD-K47832606-001-30-1 | ACH-000517 | SNU410_PANCREAS | HTS002 | 1 | 0.600649 | 3.307255 | 0.093178 | 0.837586 | 0.193202 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000517 |
BRD-K47832606-001-30-1 | ACH-000374 | HCC1143_BREAST | HTS002 | 1 | 0.378181 | 3.909151 | 0.519839 | 0.716126 | 0.119129 | 0.170961 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000374 |
BRD-K47832606-001-30-1 | ACH-000527 | OVISE_OVARY | HTS002 | 1 | 1.574697 | -6.347603 | 0.263887 | 1.226856 | 0.028131 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000527 |
BRD-K47832606-001-30-1 | ACH-000091 | OV56_OVARY | HTS002 | 1 | 0.110026 | 2.3579 | 0.724945 | 0.565415 | 0.087507 | 0.097234 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000091 |
BRD-K47832606-001-30-1 | ACH-000759 | MDAMB175VII_BREAST | HTS002 | 1 | 0.555084 | 10.387974 | 0.411952 | 0.773339 | 0.071281 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000759 |
BRD-K47832606-001-30-1 | ACH-000417 | PANC0813_PANCREAS | HTS002 | 1 | 0.35402 | 4.40984 | 0.654029 | 0.694943 | 0.102278 | 0.135216 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000417 |
BRD-K47832606-001-30-1 | ACH-000308 | EFO21_OVARY | HTS002 | 1 | 0.275524 | 3.138964 | 0.747395 | 0.680093 | 0.137733 | 0.177762 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000308 |
BRD-K47832606-001-30-1 | ACH-000991 | SNU81_LARGE_INTESTINE | HTS002 | 1 | 0.155078 | 2.158383 | 0.628351 | 0.408154 | 0.011156 | 0.01325 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000991 |
BRD-K47832606-001-30-1 | ACH-000948 | 2313287_STOMACH | HTS002 | 1 | 0.031302 | 7.267951 | 0.781909 | 0.436181 | 0.035241 | 0.035555 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000948 |
BRD-K47832606-001-30-1 | ACH-000481 | NCIH2170_LUNG | HTS002 | 1 | 0.133713 | 1.418205 | 0.804231 | 0.451814 | 0.021439 | 0.026699 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000481 |
BRD-K47832606-001-30-1 | ACH-000771 | BICR56_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.332189 | 2.776513 | 0.810202 | 0.530063 | 0.010821 | 0.016034 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000771 |
BRD-K47832606-001-30-1 | ACH-000159 | OSRC2_KIDNEY | HTS002 | 1 | 0.364305 | 0.865641 | 0.289425 | 0.643701 | 0.042633 | 0.19234 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000159 |
BRD-K47832606-001-30-1 | ACH-000929 | NCIH2110_LUNG | HTS002 | 1 | 0.106618 | 13.461645 | 0.784582 | 0.487677 | 0.038298 | 0.038986 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000929 |
BRD-K47832606-001-30-1 | ACH-000118 | HUPT3_PANCREAS | HTS002 | 1 | 0.196185 | 6.01448 | 0.742599 | 0.617108 | 0.098284 | 0.106772 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000118 |
BRD-K47832606-001-30-1 | ACH-000482 | RERFLCKJ_LUNG | HTS002 | 1 | 0.209081 | 0.961911 | 0.59392 | 0.554978 | 0.042013 | 0.073772 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000482 |
BRD-K47832606-001-30-1 | ACH-000352 | HCC1428_BREAST | HTS002 | 1 | 0.496686 | 4.68284 | 0.421858 | 0.77325 | 0.126282 | 0.36861 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000352 |
BRD-K47832606-001-30-1 | ACH-000235 | PANC0403_PANCREAS | HTS002 | 1 | 0.276355 | 0.991082 | 0.95224 | 0.637089 | 0.076973 | 0.173338 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000235 |
BRD-K47832606-001-30-1 | ACH-000900 | NCIH23_LUNG | HTS002 | 1 | 0.142428 | 1.881793 | 0.664751 | 0.569782 | 0.076868 | 0.09186 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000900 |
BRD-K47832606-001-30-1 | ACH-000479 | KNS81_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.302238 | 4.645642 | 0.559675 | 0.690271 | 0.134668 | 0.164428 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000479 |
BRD-K47832606-001-30-1 | ACH-000911 | NUGC3_STOMACH | HTS002 | 1 | 0.156934 | 6.042306 | 0.6101 | 0.599198 | 0.099179 | 0.105559 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000911 |
BRD-K47832606-001-30-1 | ACH-000401 | COLO800_SKIN | HTS002 | 1 | 0.247439 | 3.015661 | 0.710173 | 0.639461 | 0.095707 | 0.120032 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000401 |
BRD-K47832606-001-30-1 | ACH-000276 | HCC38_BREAST | HTS002 | 1 | 0.197809 | 4.403089 | 0.641381 | 0.424539 | 0.009478 | 0.010627 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000276 |
BRD-K47832606-001-30-1 | ACH-000724 | HT1376_URINARY_TRACT | HTS002 | 1 | 1.581356 | -6.764285 | 0.400425 | 1.245461 | 0.036728 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000724 |
BRD-K47832606-001-30-1 | ACH-000092 | NCIH2452_PLEURA | HTS002 | 1 | 0.179648 | 2.219766 | 0.775186 | 0.561693 | 0.056009 | 0.068448 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000092 |
BRD-K47832606-001-30-1 | ACH-000890 | SW1271_LUNG | HTS002 | 1 | 0.28275 | 2.508518 | 0.751874 | 0.611714 | 0.0523 | 0.072914 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000890 |
BRD-K47832606-001-30-1 | null | null | HTS002 | 1 | 0.151462 | 0.927242 | 0.841699 | 0.605564 | 0.110751 | 0.163442 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | false | ACH-000539_FAILED_STR |
BRD-K47832606-001-30-1 | ACH-000800 | NCIH446_LUNG | HTS002 | 1 | 0.212611 | 1.112965 | 0.654439 | 0.606946 | 0.078749 | 0.129519 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000800 |
BRD-K47832606-001-30-1 | ACH-000899 | WM88_SKIN | HTS002 | 1 | 0.406512 | 2.793613 | 0.264737 | 0.800271 | 0.381695 | 0.695644 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000899 |
BRD-K47832606-001-30-1 | ACH-000996 | HEC251_ENDOMETRIUM | HTS002 | 1 | 0.320904 | 7.023096 | 0.440961 | 0.708833 | 0.155969 | 0.180521 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000996 |
BRD-K47832606-001-30-1 | ACH-000622 | KNS42_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.494707 | 1.450434 | 0.395338 | 0.833919 | 0.414677 | 9.540067 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000622 |
BRD-K47832606-001-30-1 | ACH-000403 | NCIH747_LARGE_INTESTINE | HTS002 | 1 | 1.657332 | -1.016041 | 0.271147 | 1.322117 | 0.070825 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000403 |
BRD-K47832606-001-30-1 | ACH-000141 | SNU308_BILIARY_TRACT | HTS002 | 1 | 0.216497 | 3.151552 | 0.499031 | 0.673959 | 0.176295 | 0.211071 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000141 |
BRD-K47832606-001-30-1 | ACH-000988 | MFE319_ENDOMETRIUM | HTS002 | 1 | 0.120683 | 1.442114 | 0.746785 | 0.540134 | 0.062482 | 0.075673 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000988 |
BRD-K47832606-001-30-1 | ACH-000848 | JHH7_LIVER | HTS002 | 1 | 0.00883 | 0.467807 | 0.605265 | 0.392306 | 0.019924 | 0.020698 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000848 |
BRD-K47832606-001-30-1 | ACH-000785 | NCIH2126_LUNG | HTS002 | 1 | 0.212212 | 15.501565 | 0.68156 | 0.620645 | 0.093447 | 0.096837 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000785 |
BRD-K47832606-001-30-1 | ACH-000544 | OE21_OESOPHAGUS | HTS002 | 1 | 0.246681 | 2.047196 | 0.639905 | 0.627373 | 0.082291 | 0.114709 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000544 |
BRD-K47832606-001-30-1 | ACH-000982 | GP2D_LARGE_INTESTINE | HTS002 | 1 | 0.074166 | 2.839041 | 0.6487 | 0.311493 | 0.007341 | 0.007768 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000982 |
BRD-K47832606-001-30-1 | ACH-000021 | NCIH1693_LUNG | HTS002 | 1 | 0.252604 | 5.954565 | 0.713687 | 0.640453 | 0.093881 | 0.105657 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000021 |
BRD-K47832606-001-30-1 | ACH-000823 | KYSE140_OESOPHAGUS | HTS002 | 1 | 0.564972 | 8.366932 | 0.525436 | 0.784242 | 0.081245 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000823 |
BRD-K47832606-001-30-1 | ACH-000915 | IPC298_SKIN | HTS002 | 1 | 0.148635 | 2.444932 | 0.817013 | 0.547743 | 0.057708 | 0.066666 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000915 |
BRD-K47832606-001-30-1 | ACH-000984 | HEC6_ENDOMETRIUM | HTS002 | 1 | 0.411003 | 5.377584 | 0.486013 | 0.734041 | 0.125024 | 0.172341 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000984 |
BRD-K47832606-001-30-1 | ACH-000579 | UACC257_SKIN | HTS002 | 1 | 0.196997 | 4.327446 | 0.621179 | 0.627008 | 0.11026 | 0.123789 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000579 |
BRD-K47832606-001-30-1 | ACH-001306 | 8305C_THYROID | HTS002 | 1 | 0.233736 | 3.401729 | 0.669215 | 0.612001 | 0.073455 | 0.088403 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-001306 |
BRD-K47832606-001-30-1 | ACH-000318 | TE10_OESOPHAGUS | HTS002 | 1 | 0.510956 | 3.451241 | 0.453499 | 0.772035 | 0.108511 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000318 |
BRD-K47832606-001-30-1 | ACH-000840 | HCC366_LUNG | HTS002 | 1 | 0.197047 | 4.538247 | 0.776965 | 0.638962 | 0.12736 | 0.142227 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000840 |
BRD-K47832606-001-30-1 | ACH-000503 | BICR16_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.239478 | 0.960805 | 0.086885 | 0.570963 | 0.041402 | 0.0816 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000503 |
BRD-K47832606-001-30-1 | ACH-000726 | TE14_OESOPHAGUS | HTS002 | 1 | 0.0597 | 11.72214 | 0.718487 | 0.462359 | 0.038931 | 0.039355 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000726 |
BRD-K47832606-001-30-1 | ACH-000919 | IM95_STOMACH | HTS002 | 1 | 0.155158 | 3.437801 | 0.806267 | 0.501274 | 0.032519 | 0.036231 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000919 |
BRD-K47832606-001-30-1 | ACH-000188 | SCC25_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.239745 | 1.335901 | 0.657056 | 0.640996 | 0.102388 | 0.166924 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000188 |
BRD-K47832606-001-30-1 | ACH-000618 | SNU1041_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.314298 | 1.203351 | 0.808546 | 0.642545 | 0.063459 | 0.14453 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000618 |
BRD-K47832606-001-30-1 | ACH-000822 | SKMEL24_SKIN | HTS002 | 1 | 0.252512 | 4.548161 | 0.694863 | 0.56596 | 0.035713 | 0.041685 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000822 |
BRD-K47832606-001-30-1 | ACH-000292 | NCIH841_LUNG | HTS002 | 1 | 0.280117 | 1.466905 | 0.714638 | 0.649086 | 0.088251 | 0.154503 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000292 |
BRD-K47832606-001-30-1 | ACH-000827 | WM793_SKIN | HTS002 | 1 | 0.230942 | 3.108553 | 0.714148 | 0.594581 | 0.060022 | 0.073263 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000827 |
BRD-K47832606-001-30-1 | ACH-000411 | 769P_KIDNEY | HTS002 | 1 | 0.235906 | 1.754204 | 0.748517 | 0.618787 | 0.078957 | 0.11361 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000411 |
BRD-K47832606-001-30-1 | ACH-000139 | PANC0327_PANCREAS | HTS002 | 1 | 0.082286 | 4.95867 | 0.402811 | 0.469965 | 0.036805 | 0.038165 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000139 |
BRD-K47832606-001-30-1 | ACH-000569 | ISTMES1_PLEURA | HTS002 | 1 | 0.195015 | 3.859518 | 0.626384 | 0.535731 | 0.037099 | 0.042168 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000569 |
BRD-K47832606-001-30-1 | ACH-000741 | UBLC1_URINARY_TRACT | HTS002 | 1 | 0.224551 | 1.083615 | 0.748752 | 0.567493 | 0.044329 | 0.076849 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000741 |
BRD-K47832606-001-30-1 | ACH-000278 | COV362_OVARY | HTS002 | 1 | 0.250786 | 4.007816 | 0.850159 | 0.661543 | 0.124777 | 0.148452 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000278 |
BRD-K47832606-001-30-1 | ACH-000425 | UACC62_SKIN | HTS002 | 1 | 0.133571 | 2.716541 | 0.835834 | 0.519147 | 0.045821 | 0.051375 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000425 |
BRD-K47832606-001-30-1 | ACH-000013 | ONCODG1_OVARY | HTS002 | 1 | 0.079654 | 1.747293 | 0.816235 | 0.399542 | 0.017771 | 0.019627 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000013 |
BRD-K47832606-001-30-1 | ACH-000231 | KALS1_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.134096 | 4.395951 | 0.703685 | 0.602401 | 0.116106 | 0.124653 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000231 |
BRD-K47832606-001-30-1 | ACH-000730 | SKMEL5_SKIN | HTS002 | 1 | 0.133707 | 6.427289 | 0.668434 | 0.543506 | 0.060146 | 0.063129 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000730 |
BRD-K47832606-001-30-1 | ACH-000500 | SNU46_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.186123 | 5.86869 | 0.638694 | 0.626209 | 0.115992 | 0.12557 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000500 |
BRD-K47832606-001-30-1 | ACH-000222 | ASPC1_PANCREAS | HTS002 | 1 | 0.348398 | 3.049314 | 0.774362 | 0.621901 | 0.035853 | 0.053026 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000222 |
BRD-K47832606-001-30-1 | ACH-000477 | MALME3M_SKIN | HTS002 | 1 | 0.563401 | 3.449363 | 0.354648 | 0.750789 | 0.039301 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000477 |
BRD-K47832606-001-30-1 | ACH-000223 | HCC1937_BREAST | HTS002 | 1 | 0.666326 | 9.033428 | 0.088142 | 0.926881 | 1.192547 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000223 |
BRD-K47832606-001-30-1 | ACH-000495 | TUHR4TKB_KIDNEY | HTS002 | 1 | 0.30924 | 4.012946 | 0.584115 | 0.680665 | 0.11264 | 0.143211 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000495 |
BRD-K47832606-001-30-1 | ACH-000434 | NCIH1915_LUNG | HTS002 | 1 | 0.31085 | 1.512025 | 0.67046 | 0.776415 | 0.431661 | 0.821008 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000434 |
BRD-K47832606-001-30-1 | ACH-000744 | NCIH1623_LUNG | HTS002 | 1 | 0.177229 | 2.009605 | 0.860734 | 0.384637 | 0.007021 | 0.008729 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000744 |
BRD-K47832606-001-30-1 | ACH-000107 | CAPAN2_PANCREAS | HTS002 | 1 | 0.545662 | 2.485072 | 0.112966 | 0.804139 | 0.152475 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000107 |
BRD-K47832606-001-30-1 | ACH-000516 | CAL78_BONE | HTS002 | 1 | 0.097075 | 1.838411 | 0.712268 | 0.473611 | 0.034909 | 0.039258 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000516 |
BRD-K47832606-001-30-1 | ACH-000182 | SNU869_BILIARY_TRACT | HTS002 | 1 | 0.265129 | 4.666619 | 0.718244 | 0.577596 | 0.037805 | 0.044449 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000182 |
BRD-K47832606-001-30-1 | ACH-000898 | SNU719_STOMACH | HTS002 | 1 | 0.47826 | 2.007647 | 0.710815 | 0.682808 | 0.027399 | 0.130616 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000898 |
BRD-K47832606-001-30-1 | ACH-000040 | U118MG_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.137908 | 1.560254 | 0.578689 | 0.659567 | 0.216986 | 0.266844 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000040 |
BRD-K47832606-001-30-1 | ACH-000808 | HUH28_BILIARY_TRACT | HTS002 | 1 | 0.273508 | 1.462329 | 0.452368 | 0.767595 | 0.451824 | 0.776523 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000808 |
BRD-K47832606-001-30-1 | ACH-000447 | NCIH2228_LUNG | HTS002 | 1 | 0.141632 | 2.675443 | 0.885198 | 0.581294 | 0.087949 | 0.099608 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000447 |
BRD-K47832606-001-30-1 | ACH-000715 | SNU1214_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.307571 | 1.267058 | 0.484476 | 0.658294 | 0.083242 | 0.176862 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000715 |
BRD-K47832606-001-30-1 | ACH-000186 | NCIH2444_LUNG | HTS002 | 1 | 0.121192 | 1.422415 | 0.500482 | 0.518594 | 0.049082 | 0.059659 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000186 |
BRD-K47832606-001-30-1 | ACH-000542 | HEYA8_OVARY | HTS002 | 1 | 0.423218 | 4.779226 | 0.345201 | 0.64039 | 0.023572 | 0.034887 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000542 |
BRD-K47832606-001-30-1 | ACH-000943 | RKO_LARGE_INTESTINE | HTS002 | 1 | 0.090835 | 1.67177 | 0.592832 | 0.432664 | 0.023418 | 0.026401 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000943 |
BRD-K47832606-001-30-1 | ACH-000174 | CAL62_THYROID | HTS002 | 1 | 0.291317 | 1.401878 | 0.61475 | 0.604845 | 0.044614 | 0.083209 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000174 |
BRD-K47832606-001-30-1 | ACH-000393 | HLF_LIVER | HTS002 | 1 | 0.149017 | 5.530415 | 0.373698 | 0.634911 | 0.15557 | 0.16585 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000393 |
BRD-K47832606-001-30-1 | ACH-000018 | T24_URINARY_TRACT | HTS002 | 1 | 0.279445 | 8.222911 | 0.718671 | 0.684679 | 0.14313 | 0.15811 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000018 |
BRD-K47832606-001-30-1 | ACH-000906 | ES2_OVARY | HTS002 | 1 | 0.134151 | 1.685652 | 0.821614 | 0.494021 | 0.03443 | 0.04144 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000906 |
BRD-K47832606-001-30-1 | ACH-000784 | KYSE70_OESOPHAGUS | HTS002 | 1 | 0.699416 | 0.3392 | 0.116018 | 0.845376 | 0.063532 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000784 |
BRD-K47832606-001-30-1 | ACH-000265 | KP4_PANCREAS | HTS002 | 1 | 0.182245 | 1.911268 | 0.788031 | 0.601898 | 0.088782 | 0.112548 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000265 |
BRD-K47832606-001-30-1 | ACH-000880 | AGS_STOMACH | HTS002 | 1 | 0.324143 | 3.690438 | 0.87331 | 0.587894 | 0.02693 | 0.035744 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000880 |
BRD-K47832606-001-30-1 | ACH-000961 | ISHIKAWAHERAKLIO02ER_ENDOMETRIUM | HTS002 | 1 | 0.3914 | 4.192349 | 0.822527 | 0.629954 | 0.027385 | 0.039417 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000961 |
BRD-K47832606-001-30-1 | ACH-000847 | HGC27_STOMACH | HTS002 | 1 | 0.048421 | 3.607178 | 0.613417 | 0.490412 | 0.055348 | 0.056933 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000847 |
BRD-K47832606-001-30-1 | ACH-000896 | 647V_URINARY_TRACT | HTS002 | 1 | 0.12779 | 3.156777 | 0.756101 | 0.501675 | 0.039097 | 0.042929 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000896 |
BRD-K47832606-001-30-1 | ACH-000685 | L33_PANCREAS | HTS002 | 1 | 0.14621 | 2.53518 | 0.604751 | 0.466061 | 0.023141 | 0.026524 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000685 |
BRD-K47832606-001-30-1 | ACH-000376 | SF295_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.2079 | 2.718428 | 0.780866 | 0.538881 | 0.035203 | 0.042899 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000376 |
BRD-K47832606-001-30-1 | ACH-000428 | UO31_KIDNEY | HTS002 | 1 | 0.572987 | 1.171904 | 0.410863 | 0.740398 | 0.027158 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000428 |
BRD-K47832606-001-30-1 | ACH-000749 | DMS273_LUNG | HTS002 | 1 | 0.16178 | 3.917149 | 0.728341 | 0.528303 | 0.0425 | 0.04696 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000749 |
BRD-K47832606-001-30-1 | ACH-000572 | G361_SKIN | HTS002 | 1 | -0.088868 | 0.743712 | 0.311312 | 0.710989 | 0.717745 | 0.576021 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000572 |
BRD-K47832606-001-30-1 | ACH-000704 | OAW42_OVARY | HTS002 | 1 | 0.18698 | 0.985248 | 0.546846 | 0.606506 | 0.091496 | 0.147179 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000704 |
BRD-K47832606-001-30-1 | ACH-000457 | CAL54_KIDNEY | HTS002 | 1 | 0.370278 | 1.131461 | 0.350642 | 0.7406 | 0.185159 | 0.610128 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000457 |
BRD-K47832606-001-30-1 | ACH-000601 | MIAPACA2_PANCREAS | HTS002 | 1 | 0.195466 | 3.054522 | 0.862145 | 0.560103 | 0.049621 | 0.058367 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000601 |
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