broad_id
string | depmap_id
string | ccle_name
string | screen_id
string | upper_limit
int64 | lower_limit
float64 | slope
float64 | r2
float64 | auc
float64 | ec50
float64 | ic50
float64 | name
string | moa
string | target
string | disease.area
string | indication
string | smiles
string | phase
string | passed_str_profiling
bool | row_name
string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BRD-K47832606-001-30-1 | ACH-000663 | OVTOKO_OVARY | HTS002 | 1 | 0.219316 | 8.515367 | 0.612144 | 0.636947 | 0.109674 | 0.117368 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000663 |
BRD-K47832606-001-30-1 | ACH-000647 | TE1_OESOPHAGUS | HTS002 | 1 | 0.230715 | 1.747896 | 0.672697 | 0.607636 | 0.070871 | 0.100979 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000647 |
BRD-K47832606-001-30-1 | ACH-000243 | DANG_PANCREAS | HTS002 | 1 | 0.284159 | 4.281361 | 0.640799 | 0.612532 | 0.052339 | 0.063686 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000243 |
BRD-K47832606-001-30-1 | ACH-000255 | LMSU_STOMACH | HTS002 | 1 | 0.033488 | 11.078989 | 0.84709 | 0.54994 | 0.109027 | 0.109712 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000255 |
BRD-K47832606-001-30-1 | ACH-000335 | MSTO211H_PLEURA | HTS002 | 1 | 0.067022 | 10.860529 | 0.800652 | 0.451965 | 0.033452 | 0.033899 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000335 |
BRD-K47832606-001-30-1 | ACH-000147 | T47D_BREAST | HTS002 | 1 | 0.266885 | 2.834215 | 0.636041 | 0.576143 | 0.036592 | 0.047898 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000147 |
BRD-K47832606-001-30-1 | ACH-000090 | PC3_PROSTATE | HTS002 | 1 | 0.097811 | 0.844409 | 0.814521 | 0.483654 | 0.037759 | 0.048863 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000090 |
BRD-K47832606-001-30-1 | ACH-000171 | VMRCRCZ_KIDNEY | HTS002 | 1 | 0.67773 | 3.780734 | 0.021568 | 0.862028 | 0.156925 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000171 |
BRD-K47832606-001-30-1 | ACH-000614 | RVH421_SKIN | HTS002 | 1 | 0.300601 | 1.302141 | 0.658963 | 0.631791 | 0.060373 | 0.122306 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000614 |
BRD-K47832606-001-30-1 | ACH-000132 | JHOS2_OVARY | HTS002 | 1 | 0.254363 | 12.338974 | 0.686919 | 0.63132 | 0.082447 | 0.087336 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000132 |
BRD-K47832606-001-30-1 | ACH-000274 | HS852T_SKIN | HTS002 | 1 | 0.271823 | 1.238714 | 0.129492 | 0.729425 | 0.274079 | 0.516319 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000274 |
BRD-K47832606-001-30-1 | null | null | HTS002 | 1 | 0.179773 | 2.517844 | 0.760872 | 0.623013 | 0.11561 | 0.137991 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | false | ACH-000807_FAILED_STR |
BRD-K47832606-001-30-1 | ACH-000810 | SKMEL30_SKIN | HTS002 | 1 | 0.395335 | 4.163172 | 0.414604 | 0.729584 | 0.130389 | 0.189836 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000810 |
BRD-K47832606-001-30-1 | ACH-000343 | NCIH522_LUNG | HTS002 | 1 | 0.354323 | 3.674071 | 0.356496 | 0.703065 | 0.115308 | 0.161299 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000343 |
BRD-K47832606-001-30-1 | ACH-000022 | PATU8988S_PANCREAS | HTS002 | 1 | 0.668989 | 2.629579 | -0.058998 | 0.796441 | 0.025602 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000022 |
BRD-K47832606-001-30-1 | ACH-000192 | MFE280_ENDOMETRIUM | HTS002 | 1 | 0.192636 | 2.189467 | 0.595645 | 0.589738 | 0.072184 | 0.090148 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000192 |
BRD-K47832606-001-30-1 | null | null | HTS002 | 1 | 0.228342 | 3.112621 | 0.721031 | 0.569541 | 0.04457 | 0.05422 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | false | ACH-000409_FAILED_STR |
BRD-K47832606-001-30-1 | ACH-000959 | SNUC4_LARGE_INTESTINE | HTS002 | 1 | 0.128105 | 3.962022 | 0.802776 | 0.358158 | 0.007899 | 0.008512 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000959 |
BRD-K47832606-001-30-1 | null | null | HTS002 | 1 | 0.322935 | 2.704883 | 0.915784 | 0.602132 | 0.033377 | 0.048991 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | false | ACH-000028_FAILED_STR |
BRD-K47832606-001-30-1 | ACH-000637 | KYSE520_OESOPHAGUS | HTS002 | 1 | 0.228877 | 1.215429 | 0.702417 | 0.65952 | 0.138242 | 0.228734 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000637 |
BRD-K47832606-001-30-1 | ACH-000968 | COLO792_SKIN | HTS002 | 1 | 0.342563 | 4.328023 | 0.380967 | 0.715473 | 0.149994 | 0.195898 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000968 |
BRD-K47832606-001-30-1 | ACH-000155 | SW1990_PANCREAS | HTS002 | 1 | 0.214757 | 1.930037 | 0.842483 | 0.591478 | 0.064185 | 0.085848 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000155 |
BRD-K47832606-001-30-1 | ACH-000133 | HS729_SOFT_TISSUE | HTS002 | 1 | 0.123818 | 2.503209 | 0.673605 | 0.519727 | 0.048965 | 0.05486 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000133 |
BRD-K47832606-001-30-1 | ACH-000605 | TE6_OESOPHAGUS | HTS002 | 1 | 0.247221 | 2.059205 | 0.754324 | 0.558556 | 0.03377 | 0.047031 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000605 |
BRD-K47832606-001-30-1 | ACH-000775 | NCIH727_LUNG | HTS002 | 1 | 1.340129 | -6.886617 | 0.305596 | 1.168191 | 0.074058 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000775 |
BRD-K47832606-001-30-1 | ACH-000042 | PANC0203_PANCREAS | HTS002 | 1 | 0.292173 | 2.262436 | 0.565339 | 0.588604 | 0.035523 | 0.052364 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000042 |
BRD-K47832606-001-30-1 | ACH-000860 | NCIH358_LUNG | HTS002 | 1 | 0.375951 | 5.522596 | 0.760798 | 0.706897 | 0.104851 | 0.134956 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000860 |
BRD-K47832606-001-30-1 | ACH-000994 | HEC59_ENDOMETRIUM | HTS002 | 1 | 0.107773 | 0.807705 | 0.68558 | 0.651699 | 0.237732 | 0.321086 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000994 |
BRD-K47832606-001-30-1 | ACH-000277 | HCC1419_BREAST | HTS002 | 1 | 0.402657 | 5.472122 | 0.539262 | 0.726524 | 0.117639 | 0.158643 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000277 |
BRD-K47832606-001-30-1 | ACH-000496 | NCIH1792_LUNG | HTS002 | 1 | 0.170276 | 2.522395 | 0.415104 | 0.586879 | 0.079732 | 0.094041 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000496 |
BRD-K47832606-001-30-1 | ACH-000866 | NCIH1048_LUNG | HTS002 | 1 | 0.057024 | 1.36146 | 0.811312 | 0.385988 | 0.017893 | 0.019557 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000866 |
BRD-K47832606-001-30-1 | ACH-000869 | NCIH1568_LUNG | HTS002 | 1 | 0.168328 | 3.38637 | 0.66567 | 0.516826 | 0.035609 | 0.040197 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000869 |
BRD-K47832606-001-30-1 | ACH-000117 | EFM192A_BREAST | HTS002 | 1 | 0.467316 | 1.752502 | 0.269928 | 0.769721 | 0.150749 | 0.714856 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000117 |
BRD-K47832606-001-30-1 | ACH-000678 | MKN7_STOMACH | HTS002 | 1 | 0.344349 | 2.341931 | 0.572858 | 0.634767 | 0.044909 | 0.073917 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000678 |
BRD-K47832606-001-30-1 | ACH-000493 | SNU423_LIVER | HTS002 | 1 | 0.102317 | 1.12875 | 0.714851 | 0.480335 | 0.036068 | 0.044179 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000493 |
BRD-K47832606-001-30-1 | ACH-000468 | PK45H_PANCREAS | HTS002 | 1 | 0.509025 | 1.601809 | 0.417446 | 0.793847 | 0.170132 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000468 |
BRD-K47832606-001-30-1 | ACH-000097 | ZR751_BREAST | HTS002 | 1 | 0.156175 | 1.389226 | 0.685561 | 0.695568 | 0.303319 | 0.397161 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000097 |
BRD-K47832606-001-30-1 | ACH-000313 | KMRC3_KIDNEY | HTS002 | 1 | 0.2122 | 1.311834 | 0.760344 | 0.593288 | 0.066682 | 0.101594 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000313 |
BRD-K47832606-001-30-1 | ACH-000169 | RD_SOFT_TISSUE | HTS002 | 1 | 0.043979 | 0.976793 | 0.569177 | 0.538843 | 0.092982 | 0.102172 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000169 |
BRD-K47832606-001-30-1 | null | null | HTS002 | 1 | 0.153958 | 4.204517 | 0.76929 | 0.496968 | 0.031205 | 0.03406 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | false | ACH-000010_FAILED_STR |
BRD-K47832606-001-30-1 | ACH-000895 | CL34_LARGE_INTESTINE | HTS002 | 1 | 0.180361 | 6.295257 | 0.355604 | 0.554725 | 0.051343 | 0.055125 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000895 |
BRD-K47832606-001-30-1 | ACH-000841 | NCIH2087_LUNG | HTS002 | 1 | 0.176174 | 2.567031 | 0.692966 | 0.588456 | 0.078464 | 0.092932 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000841 |
BRD-K47832606-001-30-1 | ACH-000414 | NCIH1944_LUNG | HTS002 | 1 | 0.049855 | 9.144912 | 0.788346 | 0.464332 | 0.042074 | 0.04256 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000414 |
BRD-K47832606-001-30-1 | ACH-000026 | 253JBV_URINARY_TRACT | HTS002 | 1 | 0.179625 | 1.388001 | 0.649139 | 0.707212 | 0.315066 | 0.434186 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000026 |
BRD-K47832606-001-30-1 | ACH-000649 | 786O_KIDNEY | HTS002 | 1 | 0.211157 | 11.675057 | 0.748381 | 0.605516 | 0.078065 | 0.081821 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000649 |
BRD-K47832606-001-30-1 | ACH-000966 | IGROV1_OVARY | HTS002 | 1 | 0.17933 | 2.42986 | 0.824199 | 0.604089 | 0.092653 | 0.111238 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000966 |
BRD-K47832606-001-30-1 | ACH-000950 | LOVO_LARGE_INTESTINE | HTS002 | 1 | 0.153047 | 3.645718 | 0.7834 | 0.497731 | 0.031675 | 0.035014 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000950 |
BRD-K47832606-001-30-1 | ACH-000750 | LOXIMVI_SKIN | HTS002 | 1 | 0.333666 | 8.296873 | 0.51667 | 0.678583 | 0.092706 | 0.105856 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000750 |
BRD-K47832606-001-30-1 | ACH-000958 | SW48_LARGE_INTESTINE | HTS002 | 1 | 0.266774 | 0.503806 | -0.093518 | 0.537133 | 0.01677 | 0.076195 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000958 |
BRD-K47832606-001-30-1 | ACH-000270 | HPAC_PANCREAS | HTS002 | 1 | 0.329027 | 2.058033 | 0.463504 | 0.613063 | 0.037117 | 0.062521 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000270 |
BRD-K47832606-001-30-1 | ACH-000535 | BXPC3_PANCREAS | HTS002 | 1 | 1.263033 | -0.680512 | 0.021593 | 1.069793 | 0.006128 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000535 |
BRD-K47832606-001-30-1 | ACH-000480 | HUH7_LIVER | HTS002 | 1 | 1.381123 | -0.059533 | 0.000364 | 1.230998 | 114.292282 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000480 |
BRD-K47832606-001-30-1 | ACH-000281 | KP2_PANCREAS | HTS002 | 1 | 1.386105 | -5.223036 | 0.289613 | 1.176107 | 0.05103 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000281 |
BRD-K47832606-001-30-1 | ACH-000897 | FTC238_THYROID | HTS002 | 1 | 0.152916 | 6.311568 | 0.442876 | 0.608675 | 0.112999 | 0.119727 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000897 |
BRD-K47832606-001-30-1 | ACH-000389 | H4_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.374167 | 1.898738 | 0.39534 | 0.639504 | 0.03735 | 0.077243 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000389 |
BRD-K47832606-001-30-1 | ACH-000862 | KMBC2_URINARY_TRACT | HTS002 | 1 | 0.159287 | 5.304975 | 0.913682 | 0.508549 | 0.034387 | 0.036965 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000862 |
BRD-K47832606-001-30-1 | ACH-000776 | ONS76_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.250975 | 1.436514 | 0.79145 | 0.575295 | 0.040716 | 0.066146 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000776 |
BRD-K47832606-001-30-1 | ACH-000023 | PATU8988T_PANCREAS | HTS002 | 1 | 0.157098 | 2.568904 | 0.958449 | 0.553352 | 0.058452 | 0.067696 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000023 |
BRD-K47832606-001-30-1 | ACH-000011 | 253J_URINARY_TRACT | HTS002 | 1 | 0.192388 | 2.218039 | 0.829035 | 0.591061 | 0.073451 | 0.091435 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000011 |
BRD-K47832606-001-30-1 | ACH-000973 | 639V_URINARY_TRACT | HTS002 | 1 | 0.053086 | 4.674771 | 0.926368 | 0.299903 | 0.007657 | 0.007843 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000973 |
BRD-K47832606-001-30-1 | ACH-001024 | CHL1_SKIN | HTS002 | 1 | 0.195194 | 1.992654 | 0.667592 | 0.590995 | 0.072146 | 0.092487 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-001024 |
BRD-K47832606-001-30-1 | ACH-000971 | HCT116_LARGE_INTESTINE | HTS002 | 1 | 0.20295 | 1.861161 | 0.850531 | 0.610653 | 0.087363 | 0.115566 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000971 |
BRD-K47832606-001-30-1 | ACH-000486 | KU1919_URINARY_TRACT | HTS002 | 1 | 0.108403 | 2.444954 | 0.866664 | 0.449017 | 0.024864 | 0.027478 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000486 |
BRD-K47832606-001-30-1 | ACH-000997 | HCT15_LARGE_INTESTINE | HTS002 | 1 | 0.083699 | 3.920667 | 0.704994 | 0.492596 | 0.046371 | 0.048589 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000997 |
BRD-K47832606-001-30-1 | ACH-000552 | HT29_LARGE_INTESTINE | HTS002 | 1 | 0.157672 | 2.410343 | 0.720447 | 0.465697 | 0.021217 | 0.024828 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000552 |
BRD-K47832606-001-30-1 | ACH-000796 | MCAS_OVARY | HTS002 | 1 | 0.225379 | 2.652252 | 0.825676 | 0.615566 | 0.080991 | 0.101521 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000796 |
BRD-K47832606-001-30-1 | ACH-000652 | SUIT2_PANCREAS | HTS002 | 1 | 0.314497 | 1.637776 | 0.696319 | 0.646922 | 0.067492 | 0.123646 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000652 |
BRD-K47832606-001-30-1 | ACH-000452 | TE8_OESOPHAGUS | HTS002 | 1 | 0.27276 | 1.583684 | 0.47985 | 0.695791 | 0.172776 | 0.284278 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000452 |
BRD-K47832606-001-30-1 | ACH-000458 | CJM_SKIN | HTS002 | 1 | 0.198383 | 3.569139 | 0.692556 | 0.647301 | 0.139867 | 0.161145 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000458 |
BRD-K47832606-001-30-1 | ACH-000221 | SNU398_LIVER | HTS002 | 1 | 0.199893 | 2.031854 | 0.524884 | 0.6045 | 0.08256 | 0.106141 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000221 |
BRD-K47832606-001-30-1 | ACH-000970 | SNUC5_LARGE_INTESTINE | HTS002 | 1 | 2.317933 | -0.147893 | -0.000009 | 1.426791 | 0.000439 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000970 |
BRD-K47832606-001-30-1 | ACH-000893 | NCIH1651_LUNG | HTS002 | 1 | 0.395692 | 3.594602 | 0.652423 | 0.637095 | 0.029452 | 0.045547 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000893 |
BRD-K47832606-001-30-1 | ACH-000562 | HCC78_LUNG | HTS002 | 1 | 0.174816 | 3.372536 | 0.763555 | 0.512746 | 0.032469 | 0.036887 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000562 |
BRD-K47832606-001-30-1 | ACH-000769 | LK2_LUNG | HTS002 | 1 | 0.288916 | 2.933945 | 0.56491 | 0.636669 | 0.070246 | 0.094247 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000769 |
BRD-K47832606-001-30-1 | ACH-000384 | SW780_URINARY_TRACT | HTS002 | 1 | 0.572179 | 4.187353 | 0.325864 | 0.821473 | 0.17432 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000384 |
BRD-K47832606-001-30-1 | ACH-000505 | RKN_SOFT_TISSUE | HTS002 | 1 | 0.251319 | 4.896341 | 0.671053 | 0.656345 | 0.116284 | 0.134113 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000505 |
BRD-K47832606-001-30-1 | ACH-000765 | WM983B_SKIN | HTS002 | 1 | 0.137913 | 2.154205 | 0.670406 | 0.680375 | 0.273879 | 0.318142 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000765 |
BRD-K47832606-001-30-1 | ACH-000858 | KNS62_LUNG | HTS002 | 1 | 0.442374 | 2.195706 | 0.216692 | 0.64032 | 0.019121 | 0.051152 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000858 |
BRD-K47832606-001-30-1 | ACH-000595 | LN229_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.157089 | 1.237356 | 0.421205 | 0.734458 | 0.478981 | 0.649663 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000595 |
BRD-K47832606-001-30-1 | ACH-000052 | A673_BONE | HTS002 | 1 | 0.337332 | 1.986601 | 0.495528 | 0.615691 | 0.035959 | 0.063283 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000052 |
BRD-K47832606-001-30-1 | ACH-000979 | DU145_PROSTATE | HTS002 | 1 | 0.203092 | 3.749667 | 0.890413 | 0.612026 | 0.088758 | 0.101994 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000979 |
BRD-K47832606-001-30-1 | ACH-000571 | T98G_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.081647 | 1.476765 | 0.952634 | 0.406567 | 0.01883 | 0.021246 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000571 |
BRD-K47832606-001-30-1 | ACH-000812 | COLO783_SKIN | HTS002 | 1 | 0.223115 | 5.205187 | 0.814967 | 0.633784 | 0.103124 | 0.115523 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000812 |
BRD-K47832606-001-30-1 | ACH-000891 | HCC1438_LUNG | HTS002 | 1 | 0.176344 | 12.458439 | 0.824526 | 0.588064 | 0.078025 | 0.080797 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000891 |
BRD-K47832606-001-30-1 | ACH-000667 | HCC44_LUNG | HTS002 | 1 | 0.162717 | 1.904424 | 0.810016 | 0.535015 | 0.045652 | 0.056136 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000667 |
BRD-K47832606-001-30-1 | ACH-000734 | JHH5_LIVER | HTS002 | 1 | 0.13956 | 2.102674 | 0.540175 | 0.361914 | 0.007475 | 0.008734 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000734 |
BRD-K47832606-001-30-1 | ACH-000416 | NCIH838_LUNG | HTS002 | 1 | 0.133998 | 2.289273 | 0.960654 | 0.528932 | 0.050995 | 0.05844 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000416 |
BRD-K47832606-001-30-1 | ACH-000802 | BFTC905_URINARY_TRACT | HTS002 | 1 | 0.251739 | 2.541329 | 0.498422 | 0.631981 | 0.084568 | 0.111392 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000802 |
BRD-K47832606-001-30-1 | ACH-000946 | HEC265_ENDOMETRIUM | HTS002 | 1 | 0.187408 | 6.38216 | 0.420263 | 0.617082 | 0.103284 | 0.111172 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000946 |
BRD-K47832606-001-30-1 | ACH-000472 | HSC2_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.145892 | 1.928602 | 0.812578 | 0.573906 | 0.078981 | 0.094453 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000472 |
BRD-K47832606-001-30-1 | ACH-000962 | OC314_OVARY | HTS002 | 1 | 0.044863 | 9.357182 | 0.908821 | 0.46248 | 0.042487 | 0.042916 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000962 |
BRD-K47832606-001-30-1 | ACH-000383 | OE33_OESOPHAGUS | HTS002 | 1 | 0.239397 | 6.647969 | 0.925557 | 0.451535 | 0.009141 | 0.010083 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000383 |
BRD-K47832606-001-30-1 | ACH-000824 | KYSE510_OESOPHAGUS | HTS002 | 1 | 0.049243 | 1.548062 | 0.88339 | 0.508714 | 0.066404 | 0.071004 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000824 |
BRD-K47832606-001-30-1 | ACH-001307 | 8505C_THYROID | HTS002 | 1 | 0.312311 | 1.91373 | 0.392441 | 0.839594 | 1.047055 | 1.747136 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-001307 |
BRD-K47832606-001-30-1 | ACH-000756 | GI1_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.104418 | 1.424862 | 0.729992 | 0.591842 | 0.120139 | 0.141606 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000756 |
BRD-K47832606-001-30-1 | ACH-000681 | A549_LUNG | HTS002 | 1 | 0.266427 | 4.954124 | 0.727182 | 0.651074 | 0.098945 | 0.115376 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000681 |
BRD-K47832606-001-30-1 | ACH-000444 | LU99_LUNG | HTS002 | 1 | 0.155466 | 3.694117 | 0.758193 | 0.614903 | 0.119749 | 0.13245 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000444 |
BRD-K47832606-001-30-1 | ACH-000142 | CAL29_URINARY_TRACT | HTS002 | 1 | 0.11322 | 3.792568 | 0.727764 | 0.485813 | 0.036001 | 0.038523 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000142 |
BRD-K47832606-001-30-1 | ACH-000905 | 5637_URINARY_TRACT | HTS002 | 1 | 0.101737 | 3.329597 | 0.761006 | 0.335009 | 0.007586 | 0.008122 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000905 |
BRD-K47832606-001-30-1 | ACH-000680 | SW948_LARGE_INTESTINE | HTS002 | 1 | 0.120941 | 1.737752 | 0.702665 | 0.462996 | 0.026615 | 0.031213 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000680 |
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