input
stringlengths 1
338k
| output
sequencelengths 1
927
| id
stringlengths 40
41
| task_category
stringclasses 2
values | domain
sequencelengths 1
6
| source
stringclasses 71
values | long_task
stringclasses 212
values | language
stringclasses 2
values |
|---|---|---|---|---|---|---|---|
Context: This study was aimed to explore the mutations of ribosomal protein (RP) genes in patients with Diamond Blackfan anemia (DBA). Twenty-one cases of DBA admitted in our hospital from Dec 2008 to Aug 2012 were screened by PCR for mutations in the nine known genes associated with DBA: RPS19, RPS24, RPS17, RPL5, RPL11, RPS7, RPL35a, RPS10 and RPS26. The results found that 8 patients (38.1%) with DBA had mutations in the genes coding for ribosomal protein, in which RPS19 mutation was identified in 3 patients, RPS24, RPS7, RPL5, RPL11 and RPL35A mutations were identified respectively in 1 of the patient. No mutations were detected in RPS17, RPS10 or RPS26 genes. Thumb anomalies were found in 2 patients with RPL11 or RPL5 mutation, and hypospadias was found in 1 patient with RPS19 mutation. It is concluded that the mutation frequency of the genes coding for ribosomal protein in the patients with DBA here is lower than that in western countries. The hypospadias can be observed in some patients with RPS19 mutation and some dactyl anomalies are associated with RPL11 and RPL5 mutations.
Question: In which syndrome is the RPS19 gene most frequently mutated? | [
"dba",
"diamond blackfan anemia",
"diamond-blackfan anemia"
] | task469-734118315861426083df6a23c09503cf | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Colonel Sir Malcolm Stoddart-Scott OBE MC TD (23 September 1901 -- 15 June 1973) was a Conservative Party politician in the United Kingdom.
Question: What political party is Malcolm Stoddart-Scott a memeber of? | [
"conservative party"
] | task469-8501b4d3c8d84f649048dc6ef3b6434e | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Meanwhile, in 1274, the former Dali Kingdom was officially reorganized as the Province of Yunnan, with Sayyid Ajjal Shams al-Din Omar as governor. In May 1275, the governor sent a report to the emperor stating that the embassy had not returned; that the Burmese evidently had no intention of submitting; and that war was the only way forward. But the emperor rejected an outright invasion. Just coming off a disastrous Japanese campaign, the emperor was unwilling to commit the central government troops to what he considered a low priority affair. He was now focused on delivering the final blow against the Song; the emperor ordered the Yunnan provincial army to secure the borderlands in order to block the escape path of the Song refugees. He also sanctioned a limited border war if Pagan contested the takeover. As planned, the Yunnan army proceeded to consolidate the borderlands in 1275-76. Elsewhere, the main Mongol armies had captured most of the Song territory by 1276. By 1277, at least one Burmese vassal state named "Gold Teeth" had submitted to the Mongols. Like in 1272, the Burmese government responded by sending an army to reclaim the rebellious state; but unlike in 1272, the Mongols had posted a sizable garrison there. Though it was ultimately under Mongol command, many of the officers and most of the soldiers of the garrison were Turkic-speaking peoples or people from the further west: Turks from Samarkand, Bukhara, Merv and Nishapur, but also captive soldiers from the Persian Khwarazmid empire, the Kipchaks, and even Bulgars from the lower Volga.
Question: Which happened first - the reorganization of the Province of Yunnan, or the capture of the Song territory? | [
"the province of yunnan"
] | task469-4847d900793149fc9a0887252720330a | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Kelly Dixon attended the University of Minnesota at Duluth, majoring in anthropology.
Question: What university did Kelly Dixon attend? | [
"university of minnesota"
] | task469-7fe17c4968444b149ccfec9c691eb152 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Many different cellular pathways have evolved to protect the genome from the deleterious effects of DNA damage that result from exposure to chemical and physical agents. Among these is a process called transcription-coupled repair (TCR) that catalyzes the removal of DNA lesions from the transcribed strand of expressed genes, often resulting in a preferential bias of damage clearance from this strand relative to its non-transcribed counterpart. Lesions subject to this type of repair include cyclobutane pyrimidine dimers that are normally repaired by nucleotide excision repair (NER) and thymine glycols (TGs) that are removed primarily by base excision repair (BER). While the mechanism underlying TCR is not completely clear, it is known that its facilitation requires proteins used by other repair pathways like NER. It is also believed that the signal for TCR is the stalled RNA polymerase that results when DNA damage prevents its translocation during transcription elongation. While there is a clear role for some NER proteins in TCR, the involvement of BER proteins is less clear. To explore this further, we studied the removal of 7-methylguanine (7MeG) and 3-methyladenine (3MeA) from the dihydrofolate reductase (dhfr) gene of murine cell lines that vary in their repair phenotypes. 7MeG and 3MeA constitute the two principal N-methylpurines formed in DNA following exposure to methylating agents. In mammalian cells, alkyladenine DNA alkyladenine glycosylase (Aag) is the major enzyme required for the repair of these lesions via BER, and their removal from the total genome is quite rapid. There is no observable TCR of these lesions in specific genes in DNA repair proficient cells; however, it is possible that the rapid repair of these adducts by BER masks any TCR. The repair of 3MeA and 7MeG was examined in cells lacking Aag, NER, or both Aag and NER to determine if rapid overall repair masks TCR. The results show that both 3MeA and 7MeG are removed without strand bias from the dhfr gene of BER deficient (Aag deficient) and NER deficient murine cell lines. Furthermore, repair of 3MeA in this region is highly dependent on Aag, but repair of 7MeG is equally efficient in the repair proficient, BER deficient, and NER deficient cell lines. Strikingly, in the absence of both BER and NER, neither 7MeG nor 3MeA is repaired. These results demonstrate that NER, but not TCR, contributes to the repair of 7MeG, and to a lesser extent 3MeA.
Question: Which gene strand is targeted by transcription-coupled repair (TCR)? | [
"the transcribed strand"
] | task469-bee326cafb5c4290b5bfde7630f8382d | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: New Zealand has long been mountain hike mad. Over the last 25 years an increasing number of dedicated cycle tracks and parks have sprung up in both town and country, many developed by bike clubs and other community groups. Recreational cycling was already on a roll, when in 2009 a 50 million New Zealand dollar government fund was established to create a continuous touring route running the length of the country, supported al a grass roots level by an additional 50 million New Zealand dollars offered up by councils and focal organizations. It soon became apparent, however, that building one continuous route across the two islands was not only too ambitious, hut it also would bypass many of the most remote and interesting corners of the country. Restoring and extending historic pathways made more sense, enabling cyclists to visit fascinating historic and cultural sites while seeing natural wonders along the way, and inspiring both locals and people from overseas to ride them. The first sod of the new trails was turned by Prime Minister John Key in late 2(X)9. Since then, armed will machetes, shovels and diggers, some of the world's hest single-track designers and builders have bush-bashed, benched. sidled and switch-hacked their way through a diverse range of terrain . By the encl of 2012, 10 0f the 20 trails were open to riders, with the remainder scheduled for completion by the end of 2,013.The 2,340 km network will be even further extended by already-established trails, such as the famous 71 km Queen Charlotte Track that goes through the Marlborough Sounds al the top of the South Island.
Question: Who first started the building work of the new trails? | [
"prime minister john key."
] | task469-01f75dffedb4458d9d007eb2ecc66fb3 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Steelers' ninth game was an AFC duel with the Patriots. The Steelers trailed early as QB Tom Brady made a 19-yard TD pass to TE Rob Gronkowski. This was followed by kicker Shayne Graham getting a 31-yard field goal. The Steelers responded in the second quarter with kicker Jeff Reed nailing a 22-yard field goal. The Steelers struggled further when Brady threw another TD pass to Gronkowski, this one from 9yards out. That was followed by Brady's scramble 3yards to the endzone for a touchdown (With a failed PAT as the kick went wide-right). The Steelers scored first in the 4th quarter when QB Ben Roethlisberger completed a 6-yard TD pass to WR Emmanuel Sanders. The Steelers looked to create another scoring drive, but it came to a halt when Roethlisberger's pass was intercepted by SS James Sanders and returned 32yards for a touchdown (With a failed 2-point conversion). The Steelers tried to cut the lead with a Roethlisberger 15-yard TD pass to WR Mike Wallace, but the Patriots replied with Brady getting a 25-yard TD pass to Gronkowski. Again the Steelers tried to get closer when Roethlisberger completed a 33-yard TD pass to Wallace, but the Patriots put the game away after Graham hit a 36-yard field goal.
Question: Who caught the first touchdown pass of the game? | [
"gronkowski"
] | task469-d9463618a050474f9d8a277d600372f4 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: In ninth grade, I thought Jennifer Fever, the dark-haired girl who sat behind me in classroom, was an alien . Our class organized an activity to raise money for the library, and in one month, Jennifer read 34 books. I couldn't believe it. Surely, she was from some faraway planet where creature lived and they didn't own television sets. How could a human being, a 13-year-old girl, read 34 books in one month? I had read three books. And by "read", I mean skimmed. I mean opened and placed them on my lap while watching cartoons. Who had time to read? In addition to my favorite cartoons, I had a basketball that required playing, a baseball that required throwing, and a volleyball that required volleying. And it wasn't as if my bike could ride itself. Besides, reading was boring. And if I wanted to be bored, it would be much easier just to pay attention during Mr. Kearly's social studies class. After senior high school, my education had become very narrow: computer engineering, mathematics, physics, and not much else. Years later, I realized something: I had not memory of ever reading a book for pleasure. But there was a world of knowledge outside science and engineering, and I was tired of being ignorant of it, so I decided I would become a reader. I dived into book after book. In short, the bookworm within me had awakened. Today, I carry a book(if not two or three) with me wherever I go. An hour-long waiting for the bus is not trouble; rather, it's a chance to enjoy a few chapters of Malcolm Gladwell's latest works. Sometimes, I wish my waiting was longer.
Question: What used to make the author bored? | [
"reading."
] | task469-e13ed76d976a4d0887fc33a4a7c3c8c9 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Sir Wilfred Robarts, a famed barrister, has just been released from the hospital in which he stayed for two months following a heart attack. Returning to his practise of law, he takes the case of Leonard Vole, an unemployed man who is accused of murdering his elderly friend, Mrs. Emily French. Vole claims he's innocent, although all evidence points to him as the killer, but his alibi witness, his cold German wife Christine, instead of entering the court as a witness for the defense, becomes the witness for the prosecution and defiantly testifies that her husband is guilty of the murder. Sir Wilfred believes there's something suspicious going on with the case, particularly with Mrs. Vole.
Question: What is the name of the Elderly Lady Friend? | [
"mrs. emily french"
] | task469-812f3c0bf68c47f0a5c49b668537429c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Two divers are photographing the wreck of the Orca, Quint's boat from the first film, and are suddenly attacked and killed by a large great white shark, but not before one of the divers' camera gets a photo of the shark's eye. The shark later prowls the coastal waters of Amity Island, killing a female water skier. The female driver of the speedboat tries to defend herself by first throwing a gasoline tank at the shark (accidentally spilling some on herself) and then igniting the fuel with a flare gun. The fire ignites the gas tank and the speedboat explodes, killing the driver and leaving the shark heavily scarred on the right side of his head.In addition to these incidents, a dead killer whale is beached at a nearby lighthouse with large wounds all over its body, which Police Chief Martin Brody (Roy Scheider) suggests were caused by a great white shark. Once again, Mayor Vaughn (Murray Hamilton) doesn't share Brody's belief that the town has another shark problem and warns him not to do something hasty. Later, Brody spots a section of a ruined speedboat bobbing in the surf just off the beach. When he goes to retrieve it, he encounters the burnt remains of the female speedboat driver.Brody angrily grounds his son Mike (Mark Gruner) because of his reluctance to find a summer job, preferring to go sailing every day, and gives him a job at the beach. The following day, while Brody is in an observation tower, he sees a large shadow produced by a school of bluefish, which he mistakes for a shark. In his haste, Brody orders everyone out of the water and fires his gun, causing a panic. Later that evening, he receives the photo of the shark's eye, taken by one of the attacked divers. Brody shows it to Vaughn and his Townsmen, but they refuse to accept the evidence put in front of them. Len Peterson (Joseph Mascolo) (who has built a new resort in Amity to attract people) and the town council fire Brody for the beach incident, with Mayor Vaughn being the only one to vote against dismissal, and promote Deputy Hendricks (Jeffrey Kramer) to Brody's position.The next morning, Mike sneaks out and goes sailing with his friends, but has to take his young brother Sean (Mark Gilpin) along to stop him telling his parents about Mike's trip. Later, they go past a group of divers led by Tom Andrews (Barry Coe). Tom encounters the shark minutes after entering the water to catch lobsters and escapes, but suffers an embolism due to rushing to the surface too fast. Tina (Ann Dusenberry) and Eddie (Gary Dubin) later encounter the shark when he smashes into their sailboat, devouring Eddie and leaving Tina terrified and alone.Brody and his wife Ellen (Lorraine Gary) find the panicked diver being put into an ambulance, and Brody suspects that something must have scared him to make him come up so fast. Hendricks informs Brody that Mike has gone out sailing to the lighthouse with his friends, so Brody insists on taking the police launch to rescue them, with Ellen and Hendricks both joining him. They find Tina's boat, with Tina hiding in the hull, who confirms Brody's suspicions about the shark in the area. Hendricks and Ellen take Tina ashore in a passing boat, while Brody continues to search for the teenagers using the police launch.All seems well with the other teenagers, until the shark appears, smashing into one of their sail boats, causing panic and their boats to collide with each other. Mike is knocked unconscious and is pulled out of the water just as the shark appears; two friends take him back to the shore for help. The rest of the teens remain floating on the wreckage of tangled boats, drifting out toward the open sea. A Harbor Patrol marine helicopter arrives and a line is rigged to tow the boats to shore, but before the pilot can tow them, the shark attacks the chopper causing it to crash into the water. Sean also falls into the water, but is quickly saved by Marge (Martha Swatek)
Question: Who was police chief? | [
"martin brody"
] | task469-a5e69875970f41a3ae32cee2206fa5f8 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Names in Marble (Estonian: Nimed marmortahvlil) is an Estonian 2002 film directed by Elmo Nuganen.
Question: The film Names in Marble was directed by whom? | [
"elmo nüganen"
] | task469-aa79c8b9b4d545e7aea116fc19256252 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: A lonely old woman who longs for a child is given a seed by a good witch. When planted, the seed grows into a flower, and inside the blossom is a tiny girl the size of the old woman's thumb. The old woman names the girl Thumbelina and raises her as her own. Although Thumbelina loves her mother, she craves companionship from someone her own size. One night, Cornelius, the fairy prince, stumbles upon Thumbelina after hearing her beautiful singing. The two take a ride on Cornelius' bumblebee, and fall in love; during this ride Mrs. Toad and her son Grundel are enchanted by Thumbelina's singing. Cornelius promises to return the next day, but after he's gone, Mrs. Toad kidnaps Thumbelina from her bed and takes her away. Thumbelina awakens on Mrs. Toad's show boat. Mrs. Toad wants Thumbelina to join their troupe and marry Grundel, who is in love with her. They leave Thumbelina alone on a lily pad in order to fetch a priest, but a friendly swallow, Jacquimo (the narrator of the film), overhears Thumbelina's cries for help and frees her. Jacquimo's friends, the jitterbugs, promise to help Thumbelina get home safely while Jacquimo sets off to find Cornelius. Meanwhile, Cornelius learns of Thumbelina's kidnapping and ventures out to find her. While trying to get home, Thumbelina is ambushed by Berkeley Beetle, who scares the jitterbugs away. He is enamoured with her singing, and promises to show her the way home if she sings at his Beetle Ball first. Thumbelina agrees, but when she's received poorly at the Beetle Ball, Beetle kicks her out without helping her. Winter is approaching. Jacquimo accidentally impales his wing on a thorn and is knocked out by the cold, while Cornelius falls into a lake and is frozen in ice. Grundel, who is searching for Thumbelina, finds Beetle and discovers she is in love with Prince Cornelius and upon some convincing from Beetle, decides to find and kidnap Cornelius to lure Thumbelina to him. Grundel forces Beetle to help him as Grundel steals his wings and won't return them until Beetle has found and captured Cornelius. Thumbelina is taken in by Miss Fieldmouse, who tells her that Cornelius has died. The two visit Miss Fieldmouse's neighbor, Mr. Mole who tells them about a dead bird he found in his tunnel earlier that day. It turns out to be Jacquimo, who Thumbelina discovers to be only unconscious. Mr. Mole wishes to marry Thumbelina; heartbroken over Cornelius's death, Thumbelina accepts. Jacquimo awakens under Thumbelina's care and leaves to find Cornelius, refusing to believe that he is dead. Meanwhile, Beetle brings Cornelius's frozen body to Grundel and informs him that Thumbelina is going to marry the Mole. After the two leave to stop the wedding, the young jitterbugs thaw Cornelius's body out. At the wedding, Thumbelina realizes at the last moment that she can't marry someone she does not love and refuses to take the vows. Grundel and Beetle crash the wedding, but Thumbelina flees from them and Mr. Mole. Cornelius intercepts the crowd and confronts Grundel, the ensuing fight resulting in them both falling into an abyss. Once outside and free, Thumbelina is reunited with Jacquimo, who takes her to Cornelius' kingdom, the Vale of the Fairies. Cornelius appears, having survived the fall, the pair are reunited, and Thumbelina accepts his proposal of marriage. The two kiss, and Thumbelina is granted her own wings. With Thumbelina's mother and the fairy court in attendance, Thumbelina and Cornelius are married and depart on their honeymoon on Cornelius's bumblebee. Images shown during the credits reveal that Beetle resumed his singing career and had gotten his wings back, Ms. Fieldmouse married Mr. Mole, and Grundel also survived the fall with minor injuries and married a female toad (implying that he lost interest in Thumbelina).
Question: Who does Thumbelina marry? | [
"prince",
"prince cornelius",
"thumbelina and cornelius are married and depart on their honeymoon on cornelius's bumblebee"
] | task469-aa560e04d4b6479d818589499dc360bd | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The female reproductive organs include the vagina, uterus, fallopian tubes, and ovaries ( Figure 1.1). The breasts are not shown in this figure. They are not considered reproductive organs, even though they are involved in reproduction. They contain mammary glands that give milk to feed a baby. The milk leaves the breast through the nipple when the baby sucks on it. The vagina is a cylinder-shaped organ found inside of the female body. One end of the vagina opens at the outside of the body. The other end joins with the uterus. During sexual intercourse, sperm may be released into the vagina. If this occurs, the sperm will move through the vagina and into the uterus. During birth, a baby passes from the uterus to the vagina to leave the body. The uterus is a hollow organ with muscular walls. The part that connects the vagina with the uterus is called the cervix. The uterus is where a baby develops until birth. The walls of the uterus grow bigger as the baby grows. The muscular walls of the uterus push the baby out during birth. This drawing shows the organs of the female reproductive system. It shows the organs from the side. Find each organ in the drawing as you read about it in the text. The two ovaries are small, oval organs on either side of the uterus. Each ovary contains thousands of eggs, with about 1-2 million immature eggs present at birth and 40,000 immature eggs present at puberty, as most of the eggs die off. The eggs do not fully develop until a female has gone through puberty. About once a month, on average one egg completes development and is released by the ovary. The ovaries also secrete estrogen, the main female sex hormone. The two fallopian tubes are narrow tubes that open off from the uterus. Each tube reaches for one of the ovaries, but the tubes are not attached to the ovaries. The end of each fallopian tube by the ovary has fingers ( Figure 1.1). They sweep an egg into the fallopian tube. Then the egg passes through the fallopian tube to the uterus. If an egg is to be fertilized, this will occur in the fallopian tube. A fertilized egg then implants into the wall of the uterus, where it begins to develop. An unfertilized egg will flow through the uterus and be excreted from the body.
Question: what organ secretes estrogen? | [
"the ovary"
] | task469-6ede4ac153fa43fca4709ee2936e8e8c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: TAROM Flight 3107 was a charter flight operated by a Boeing 737-300 that, on 30 December 2007, during the takeoff procedure, hit a service car carrying out repair work on lighting equipment on the runway at Henri Coanda International Airport in Otopeni, Romania.
Question: When did TAROM Flight 3107 occur? | [
"30 december 2007"
] | task469-13ad3acaa4224ee0bbb61efbe649c08b | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The sperm and egg dont look anything like a human baby ( Figure 1.1). After they come together, they will develop into a human being. How does a single cell become a complex organism made up of billions of cells? Keep reading to find out. Sexual reproduction happens when a sperm and an egg cell combine together. This is called fertilization. Sperm are released into the vagina during sexual intercourse. They swim through the uterus and enter a fallopian tube. This is where fertilization normally takes place. A sperm that is about to enter an egg is pictured below ( Figure 1.1). If the sperm breaks through the eggs membrane, it will immediately cause changes in the egg that keep other sperm out. This ensures that only a single sperm can penetrate an egg. It will also cause the egg to go through meiosis. Recall that meiosis, cell division that creates the egg, begins long before an egg is released from an ovary. In fact, it begins prior to birth. The sperm and egg each have only half the number of chromosomes as other cells in the body. These cells are haploid, with a single set of chromosomes. This is because when they combine together, they form a cell with the full number of chromosomes. The cell they form is called a zygote. The zygote is diploid, with two sets of chromosomes, one from each parent. A human zygote has two sets of 23 chromosomes, for a total of 46 chromosomes (23 pairs). The zygote slowly travels down the fallopian tube to the uterus. As it travels, it divides by mitosis many times. It forms a hollow ball of cells. After the ball of cells reaches the uterus, it fixes itself to the side of the uterus. This is called implantation. It usually happens about a week after fertilization. Now the implanted ball of cells is ready to continue its development into a baby boy or girl.
Question: how do eggs develop? | [
"through meiosis"
] | task469-306f9200d21848d7854f7c3af86352c9 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Darma (Pierre Andre) is traumatised by the mysterious death of his fiancee, Rose (Intan Ladyana) who had killed herself. Unknown to him, Rose had been haunted by a malicious spirit which they had brought to her home after picking up a small jar found washed up at the beach. Apparently, the spirit had been imprisoned and was inadvertently released by the couple.At her home, after her death, before leaving Darma had taken the small jar with him, and with it, the malignant spirit.Not satisfied with why Rose had suddenly killed herself, Darma decides to investigate the case with the help of Rose's twin sister, Seri, (also played by Intan Ladyana). As they probe into the death, a series of strange occurrences start to unravel, leaving Darma in a disturbed state of mind that affects his life and career. When he is advised to take a week's break from work, he returns to his village to rest. Unknown to him, he is only getting closer to solving his fiancee's death and the truth behind the strange happenings.It was Darma's senile grandmother who could see the ghost and had unwittingly invited the spirit into the house. In Malay belief, certain spirits cannot enter the house unless invited in. This is similar to the vampire mythology in the West. The ghost in this movie is called Saka. Saka was a ghost that has been kept by the elder for some uncertified reason. Mostly, Saka starts to give problems when it's owner die and Saka needs to be feed. Mostly, Saka will haunt the next generation of the owner.
Question: Who is Rose's twin sister? | [
"seri"
] | task469-bc282551023c4f70ac98f2f6eec15254 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The week 3 matchup vs. the Texans proved to be a greater challenge for the Patriots than the Saints had been in week 2. The Patriots scored first on a 7-play drive ending with a Tom Brady 5-yard throw to Rob Gronkowski, who was playing with a groin injury that took him out of the previous week's game. The game would progress through seven lead changes, as Texans rookie quarterback DeShaun Watson would go drive-for-drive against Brady. Watson threw two touchdowns, one of which to his tight end Ryan Griffin, who attended college in New England at Connecticut. Two field goals late in the game would give the Texans their final lead at 33-28. With less than 2:25 remaining in the game, Brady led the Patriots on a frantic 8-play 71-yard drive that culminated in a 25-yard reception by Brandin Cooks to give the Patriots the 36-33 win.
Question: Which team did the patriots play in week 2? | [
"saints"
] | task469-6b75be3b6b094ccda2021b9d5798e573 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: How quickly is the human population growing? If we look at worldwide human population growth from 10,000 BCE through today, our growth looks like exponential growth. It increased very slowly at first, but later grew faster and faster as the population increased in size ( Figure 1.1). And recently, the human population has increased at a faster pace than ever before. It has taken only 12 years for the worlds population to increase from six billion to seven billion. Considering that in the year 1804, there were just one billion people, and in 1927, there were just two billion people (thats 123 years to increase from 1 to 2 billion), the recent increase in the human population growth rate is characteristic of exponential growth. Does this mean there are unlimited resources? Worldwide human population growth from 10,000 BCE through today. On the other hand, if you look at human population growth in specific countries, you may see a different pattern. On the level of a country, the history of human population growth can be divided into five stages, as described in Table 1.1. Some countries have very high birth rates, in some countries the growth rate has stabilized, and in some countries the growth rate is in decline. Stage 1 2 3 4 5 Description Birth and death rates are high and population growth is stable. This occurred in early human history. Significant drop in death rate, resulting in exponential growth. This occurred in 18th- and 19th-century Eu- rope. Population size continues to grow. Birth rates equal death rates and populations become stable. Total population size may level off. The United Nations and the U.S. Census Bureau predict that by 2050, the Earth will be populated by 9.4 billion people. Other estimates predict 10 to 11 billion. There are two different beliefs about what type of growth the human population will undergo in the future: 1. Neo-Malthusians believe that human population growth cannot continue without destroying the environment, and maybe humans themselves. 2. Cornucopians believe that the Earth can give humans a limitless amount of resources. They also believe that technology can solve problems caused by limited resources, such as lack of food. The Cornucopians believe that a larger population is good for technology and innovation. The 5-stage model above predicts that when all countries are industrialized, the human population will eventually level out. But many scientists and other Neo-Malthusians believe that humans have already gone over the Earths carrying capacity. That means, we may have already reached the maximum population size that can be supported, without destroying our resources and habitat. If this is true, then human overpopulation will lead to a lack of food and other resources. Overpopulation may also lead to increased disease, and/or war. These problems may cause the population of humans to crash. If these issues are not controlled, could the human population go extinct? Which of the above theories makes sense to you? Why?
Question: which is the last stage of human population growth? | [
"total population size may level off."
] | task469-ece1a5981a894aba858479f486d74f96 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Newspaper columnist John Klein (Richard Gere) and his wife Mary (Debra Messing) are involved in an accident when Mary swerves to avoid a black, flying figure. John survives the crash unscathed, but Mary is hospitalized. After Mary dies of an unrelated brain tumor, John discovers mysterious drawings of the creature that she had created prior to the night of the accident. Two years later, John becomes lost in West Virginia and inexplicably finds himself in Point Pleasant, hundreds of miles off his route. Driving in the middle of the night, his car breaks down; and he walks to a nearby house to get help. The owner, Gordon Smallwood (Will Patton), reacts violently to John's appearance and holds him at gunpoint. Local police officer Connie Mills (Laura Linney) defuses the situation while Gordon explains that this is the third consecutive night John has knocked on his door asking to use a phone, much to John's confusion. John stays at a local motel and considers how he ended up so far from his original destination. Officer Mills mentions to John that many strange things have been occurring in the past few weeks and that people report seeing a large winged creature like a giant moth with red eyes. She also tells John about a strange dream she had, in which the words "Wake up, Number 37" were spoken to her. While conversing with Gordon one day, it is revealed to John that he had heard voices from his sink telling him that, in Denver, "99 will die". While discussing the day's events at a local diner, John notices that the news is showing a story on an airplane crash in Denver that killed all 99 passengers aboard. The next night, Gordon frantically explains that he had met the voices in his head, a being named Indrid Cold Later that night, Gordon calls John and says that he is standing with a character named Indrid Cold. While John keeps Cold on the line, Officer Mills checks on Gordon. Cold answers John's questions, convincing him that he is a supernatural being. This episode starts a string of supernatural calls to John's motel room. One tells him that there will be a great tragedy on the Ohio River. Later, John receives a call from Gordon and rushes to his home to check on him. He finds Gordon outside, dead from exposure. John becomes obsessed with the being, dubbed Mothman. He meets an expert on the subject, Alexander Leek (Alan Bates), who explains its nature and discourages John from becoming further involved. However, when John learns the governor (Murphy Dunne) plans to tour a chemical plant located on the Ohio River the following day, he becomes convinced the tragedy will occur there. Officer Mills and the governor ignore his warnings, and nothing happens during the tour. Soon afterwards, John receives a mysterious message that instructs him to await a call from his deceased wife Mary back in Georgetown, and he returns home. On Christmas Eve, Officer Mills calls and convinces him to ignore the phone call from "Mary", return to Point Pleasant, and join her. Though anguished, John agrees. As John reaches the Silver Bridge, a malfunctioning traffic light causes traffic congestion. As John walks onto the bridge to investigate, the bolts and supports of the bridge strain. The bridge comes apart, and John realizes that the prophesied tragedy on the Ohio River was about the bridge. As the bridge collapses, Officer Mills's car falls into the water. John jumps in after her and pulls her from the river and up to safety. As the two sit on the back of an ambulance, they see that 36 people have been killed, making Connie the "number 37" from her dream. The epilogue displays a series of graphics that state the cause of the bridge collapse was never fully determined. It also states that, although the Mothman has been sighted in other parts of the world, it was never seen again in Point Pleasant.
Question: Who was driving the car that was in an accident? | [
"mary"
] | task469-470e2f8b87db4c2eb7336ab99e08dd25 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Seismic waves are measured on a seismograph. Seismographs contain a lot of information, and not just about earthquakes. A seismograph is a machine that records seismic waves. In the past, seismographs produced a seismogram. A seismogram is a paper record of the seismic waves the seismograph received. Seismographs have a weighted pen suspended from a stationary frame. A drum of paper is attached to the ground. As the ground shakes in an earthquake, the pen remains stationary but the drum moves beneath it. This creates the squiggly lines that make up a seismogram (Figure 7.33). Modern seismographs record ground motions using electronic motion detectors. The data are recorded digitally on a computer. Seismograms contain a lot of information about an earthquake: its strength, length and distance. Wave height used to determine the magnitude of the earthquake. The seismogram shows the different arrival times of the seismic waves (Figure 7.34). The first waves are P-waves since they are the fastest. S-waves come in next and are usually larger than P-waves. The surface waves arrive just after the S-waves. If the earthquake has a shallow focus, the surface waves are the largest ones recorded. A seismogram may record P-waves and surface waves, but not S-waves. This means that it was located more than halfway around the Earth from the earthquake. The reason is that Earths outer core is liquid. S-waves cannot travel One seismogram indicates the distance to the epicenter. This is determined by the P-and S-wave arrival times. If a quake is near the seismograph, the S-waves arrive shortly after the P-waves. If a quake is far from the seismograph, the P-waves arrive long before the S-waves. The longer the time is between the P-and S-wave arrivals, the further away the earthquake was from the seismograph. First, seismologists calculate the arrival time difference. Then they know the distance to the epicenter from that seismograph. Next, the seismologists try to determine the location of the earthquake epicenter. To do this they need the distances to the epicenter from at least three seismographs. Lets say that they know that an earthquakes epicenter is 50 kilometers from Kansas City. They draw a circle with a 50 km radius around that seismic station. They do this twice more around two different seismic stations. The three circles intersect at a single point. This is the earthquakes epicenter (Figure 7.35). The ways seismologists measure an earthquake have changed over the decades. Initially, they could only measure what people felt and saw, the intensity. Now they can measure the energy released during the quake, the magnitude. Early in the 20th century, earthquakes were described in terms of what people felt and the damage that was done to buildings. The Mercalli Intensity Scale describes earthquake intensity. There are many problems with the Mercalli scale. The damage from an earthquake is affected by many things. Different people experience an earthquake differently. Using this scale, comparisons between earthquakes were difficult to make. A new scale was needed. Charles Richter developed the Richter magnitude scale in 1935. The Richter scale measures the magnitude of an earthquakes largest jolt of energy. This is determined by using the height of the waves recorded on a seismograph. Richter scale magnitudes jump from one level to the next. The height of the largest wave increases 10 times with each level. So the height of the largest seismic wave of a magnitude 5 quake is 10 times that of a magnitude 4 quake. A magnitude 5 is 100 times that of a magnitude 3 quake. With each level, thirty times more energy is released. A difference of two levels on the Richter scale equals 900 times more released energy. The Richter scale has limitations. A single sharp jolt measures higher on the Richter scale than a very long intense earthquake. Yet this is misleading because the longer quake releases more energy. Earthquakes that release more energy are likely to do more damage. As a result, another scale was needed. The moment magnitude scale is the favored method of measuring earthquake magnitudes. It measures the total
Question: paper record of seismic waves produced by a seismograph | [
"seismogram"
] | task469-ef7f22ed7d024c87b4269bda299c3cf1 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: New England, the late 1950s. Todd Anderson (Ethan Hawke), a lonely and painfully shy teenager, who is under pressure by his stern parents because he must live up to his older brother's reputation to attend Yale and become a lawyer, arrives for the new semester at the Welton Academy for boys -- Todd's brother also attended Welton and was a popular and well-regarded student there. This semester begins during an orientation gathering with a speech given by the stern Headmaster Nolan (Norman Lloyd), who states the academy's four pillars: Tradition, Honor, Discipline, and Excellence. Todd meets Neil Perry (Robert Sean Leonard) an ambitious student whom becomes his dorm roommate.Later in his dorm, Neil is ordered by his grumpy and domineering father (Kurtwood Smith) to drop his involvement with the school annual in order to maintain good grades so the boy may become a doctor much as he has done. Neil is under pressure from his stern father's will. Also, Mr. Perry tells Neil that Mrs. Perry also wants him to become a doctor, which further worries the boy. A little later, Todd tells Neil that he is in a similar situation with his parents involving his older brother who also attended Welton a few years ago, graduated, and attended Yale Law School and became a lawyer and his parents want the exact same thing for him. But Todd does not have the courage to tell his parents that he instead wants to be a writer, not a lawyer.During the first day of classes Todd and Neil experience the various teaching methods which include speeches by the trig teacher, as well as the Latin teacher, and the math teacher who states that "all 20 questions at the end of the first chapter are due tomorrow". In stark contrast to these orthodox teaching methods, the guys see a different side of the school when they attend English class taught by the newly arrived (and liberal-minded) Mr. Keating (Robin Williams), whom they met briefly during the orientation -- Keating tells his class he was also a student at Welton ("Helton" as the students secretly refer to the institution) himself many years ago. Keating enters his class whistling the 1812 Overture, and he first takes the boys out in the hallway to the school's displays cases containing artifacts of the school's sports achievements. He tells them that they all have the potential to become powerful individuals, and they are responsible for what their futures will hold. These two actions show his difference from the other teachers because no other teacher would commit the actions he does. Also, he tells the boys they may call him "Oh Captain, my Captain", if they dare. These examples of Mr. Keating's teachings show the boys how to think for themselves. Mr. Keating then tells the boys "Carpe Diem", which is Latin for "seize the day".In addition to Todd and Neil, a small group of other students whom include the lovesick Knox Overstreet (Josh Charles), the flip Charlie Dalton (Gale Hansen), the pragmatic Richard Cameron (Dylan Kussman), liberal Steven Meeks (Allelon Ruggiero) and the moderate Gerard Pitts (James Waterston), also react to the first day's lesson with comments from "that was weird" to "neat". Cameron asks if anything Keating told them will be on a future test and the boys respond with mild scorn.The next day Keating starts the class with a traditional teaching approach by having Neil read out loud the introduction to their poetry textbook, which describes how to rate the quality of poetry according to mathematical plotting. Keating finds such mathematical criticism ridiculous and instructs his pupils to rip out the essay which is one of three ways that he demonstrates freedom of expression and non-conformity. When some students hesitate, he tells them "this is not the Bible. This is a battle, a war. You will have to learn to think for yourselves." He later has the students stand on his desk as a reminder to look at the world in a different way.A few days later, Knox Overstreet is asked to attend a dinner party at the Danburry
Question: Who restarts the club? | [
"neil",
"the boys"
] | task469-f85adeb9cd264cdeba1f0ef8ebd7aae7 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: McLeod syndrome and chorea-acanthocytosis are classified with the so-called neuroacanthocytosis group of syndromes. Both lead to progressive basal ganglia degeneration and were not easily distinguished in the past. With the discovery of their molecular bases, mutations of the X-linked gene XK and autosomal recessive mutations of the gene coding for chorein, respectively, the two phenotypes can now be differentiated and extend the diagnostic spectrum in patients presenting with chorea. The present review compares the two conditions and proposes a practical approach to diagnosis and treatment. Better-defined disease concepts should eventually replace the umbrella term of "neuroacanthocytosis." Animal models are needed to understand the underlying mechanisms. A final common pathway is likely for the pathogenesis of these conditions and is most probably shared with Huntington's disease.
Question: Mutation of which gene is associated with McLeod syndrome? | [
"xk"
] | task469-0b3f273bb3c2482fa1eef0fef4d7e1e2 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Many disorders of the reproductive system are not sexually transmitted infections. They are not caused by pathogens, so they dont spread from person to person. They develop for other reasons. The disorders are different between males and females. In both genders, the disorders could cause a little discomfort, or they could cause death. Most common disorders of the male reproductive system involve the testes. For example, injuries to the testes are very common. In teenagers, injuries to the testes most often occur while playing sports. An injury such as a strike or kick to the testes can be very painful. It may also cause bruising and swelling. Such injuries do not usually last very long. Another disorder of the testes is cancer. Cancer of the testes is most common in males aged 15 to 35. It occurs when cells in the testes grow out of control. The cells form a lump called a tumor. If found early, cancer of the testes usually can be easily cured with surgery. Disorders of the female reproductive system may affect the vagina, uterus, or ovaries. They may also affect the breasts. One of the most common disorders is vaginitis. This is redness and itching of the vagina. It may be due to irritation by soap or bubble bath. Another possible cause of vaginitis is a yeast infection. Yeast normally grow in the vagina. A yeast infection happens when the yeast multiply too fast and cause symptoms. A yeast infection can be treated with medication. Bubble baths may be fun, but for women and girls they can cause irritation to the vagina. A common disorder of the ovaries is an ovarian cyst. A cyst is a sac filled with fluid or other material. An ovarian cyst is usually harmless, but it may cause pain. Most cysts slowly disappear and do not need treatment. Very large or painful cysts can be removed with surgery. Many teen girls have painful menstrual periods. They typically have cramping in the lower abdomen. Generally, this is nothing to worry about. Taking a warm bath or using a heating pad often helps. Exercise can help as well. A pain reliever like ibuprofen may also work. If the pain is severe, a doctor can prescribe stronger medicine to relieve the pain. The most common type of cancer in females is breast cancer. The cancer causes the cells of the breast to grow out of control and form a tumor. Breast cancer is rare in teens. It becomes more common as women get older. If breast cancer is found early, it usually can be cured with surgery.
Question: this is one of the most common disorders in females. | [
"vaginitis"
] | task469-d0bccc60c44e4342a60ea7e6518c039a | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: [[Hrothgar]], king of Danelands, and a group of mounted and helmeted warriors chase a large and burly man, whom they consider a monstrous [[troll]], and his young son across a large open field until father and son find themselves on the edge of deep cliff overlooking a beach and a large sea. The father directs his young son, [[Grendel]], to climb down and hide from the attackers' view. The Danes shoot the father dead with their arrows and his dead body plunges down onto the beach far below. The Danish king walks towards the cliff edge and sees the young Grendel hanging but chooses to spare him.Later, Grendel is on the beach below and finds his father's body. After failing to move the large and heavy corpse, the boy takes a sword and cuts the head off to take it home.Many years later, the severed (and mummified) head is inside a cave where the boy Grendel has grown up to be as large and burly as his father. Grendel bloodies his own forehead with stones to express his vengeful anger towards the Danes and the beginning of his own murderous campaign of revenge.When Hrothgar finds twenty of his warriors killed inside his great hall, the Danish king falls into a depression. [[Beowulf (hero)|Beowulf]], with the permission of [[Hygelac]], king of [[Gotaland|Geatland]], sails to Daneland with thirteen Geats on a mission to slay Grendel for Hrothgar.The arrival of Beowulf and his warriors is welcomed by Hrothgar, but the king's village has fallen into a deep despair and many of the pagan villagers convert to Christianity at the urging of an [[Irish monk]]. While Grendel does go into Hrothgar's village during the night, he flees rather than fight.Beowulf learns more about Grendel from Selma the witch and seer, who tells Beowulf that Grendel will not fight him because Beowulf has committed no wrong against him. A villager, recently baptized and thus now unafraid of death, leads Beowulf and his men to the cliff above Grendel's cave, but without a rope they are afraid to die descending to the cave itself, and turn back without even seeing the cave. When that villager is found broken and dead, Beowulf and his men return with a rope and gain entry to Grendel's secret cave. Grendel being absent, one of Beowulf's vengeful men mutilates the mummified head and shrine of Grendel's slain father.That night, Grendel attacks Beowulf and his men while they sleep in Hrothgar's great hall, killing the Geat who desecrated his father's head and then, revenge satisfied, leaps out from the second story, but is caught in a trap by Beowulf, leaving Grendel hanging by his right arm. Grendel, refusing capture, escapes by hacking off his own arm. Grendel, bleeding severely, manages to reach the same beach where he had once found his father's slain corpse and wades into the water, where he dies, his body claimed by a mysterious webbed hand. Hrothgar admits to Beowulf that he had killed Grendel's father for stealing a fish but had spared the child-troll Grendel out of pity.There is great celebration in the hall of Hrothgar, and the king's mood has been livened up by the defeat of Grendel, whose severed arm is kept by the Danes as a trophy.In revealing more about Grendel's nature, Selma recounts how Grendel had once visited her hut and clumsily raped her and has protected her since that day, troubling Beowulf all the more. Yet that does not stop him from moving forward to kiss Selma, who deftly slaps him for tying her up earlier in the film, which he did in an attempt to get her to lead him to Grendel. Nevertheless, she then pulls his head forward and kisses him, quickly initiating and taking the lead in their lovemaking as she straddles him down on her bed.The Danes are later attacked by [[Grendel's mother]], the Sea Hag. Beowulf finds her lair, where she placed Grendel's dead body along with a pile of treasure, and slays Grendel's mother with
Question: Who did Beowulf bury with ceremony? | [
"grendel"
] | task469-423f8ce32f534eb0b70f32707ca3e2e8 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The film opens where the previous film ended, set a few years later, where Rafiki (Robert Guillaume) gathers the animals of the Pride Lands together for the presentation of Simba (Matthew Broderick) and Nalas (Moira Kelly) new daughter Kiara. Mufasa's spirit (James Earl Jones) watches over the ceremony. Later, Simba becomes very overprotective of an older Kiara (Michelle Horn), assigning Timon and Pumbaa (Nathan Lane and Ernie Sabella) to watch her. One day as Kiara was playing, she fell into a small pond as Timon and Pumbba got her back onto land. Kiara tells them only half of her is a princess. Pumbba asks, "Well, who's the other half?" While they wait for her to answer, they start having a snack. Then they started arguing about slimy and crunchy grubs. While they were arguing, Kiara sneaks into the "Outlands" where she meets a young cub named Kovu (Ryan O'Donohue). After escaping a river filled with nile crocodiles, the two become friendly, unaware they are being watched by Kovu's mother, Zira (Suzanne Pleshette). Simba arrives and confronts Zira, who reminds Simba that he exiled the Outsiders, and that if he wants to punish them, Kovu is Scar's hand-chosen successor. Unwilling to harm the cub, Simba orders them to leave. Later Simba scolds Kiara for endangering herself. In the Outlands, Zira's eldest son, Nuka (Andy Dick), complains to his younger sister Vitani (Lacey Chabert) about Kovu's status as "the Chosen One" the cub chosen by Scar to lead the pride after his death. ("I should've been the "Chosen One". I'm the strongest, I'm the smartest, I'm the oldest, etc.") At that moment, Zira returns and scolds both of her sons, but Kovu accidentally gives her the idea to use Kovu's new friendship with Kiara as a means of exacting her revenge on Simba for Scar's death. Now an adult, Kiara (Neve Campbell) heads out from home for her first solo hunt, however Simba again sends Timon and Pumbaa to follow and watch her progress after he promised to let Kiara hunt on her own. Furious to find out her father still insists on maintaining surveillance, Kiara goes further from home to hunt, though is still unsuccessful in her efforts. Meanwhile, Zira's plan to implant Kovu in Simba's pride has been set in motion; Nuka and Vitani (Jennifer Lien) set fire to the plains where Kiara is hunting, causing her to faint and giving Kovu (Jason Marsden) the chance to rescue her. Drawn by the smoke, Simba finds them together and reluctantly accepts Kovu's request to come to Pride Rock in return for saving Kiara's life, though he forces Kovu to sleep outside. That same night, Simba has a nightmare about his father's death, where Scar suddenly morphs into Kovu and Simba takes his father's place falling off the cliff. The next morning, he goes outside to a watering hole where Kovu contemplates attacking him, but Kiara interrupts and they go off together so Kovu can help her learn how to hunt. Kiara kept on failing. During the lesson, Kovu was setting an example for Kiara, thinking Timon was just an ordinary meerkat. They run into Timon and Pumbaa struggling with some birds, so the two lions help them chase the birds off. Together, they have fun playing, something Kovu notes he has never experienced before. That night, Kovu tells Kiara that he is not Scar's real son, but "was a part of him". Simba watches from above, seeking guidance from the "Great Kings" and Nala advises him to give Kovu a chance, because he is not his father. Kovu decides to leave after he almost confesses his real intentions to Kiara, but Rafiki stops him and invites the young lions to experience "Upendi" love. After a musical journey through the jungle, the two fall in love. In the morning, Simba invites Kovu for a walk and tells him the true story of
Question: Who attacks Simba? | [
"zira, her son and daughter and her pride.",
"zira"
] | task469-4939244c7d094a7c9a0a177fff8abcbe | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Jack Elgin is the European editor of The Economist, which is based in London, England. Jack has a wife named Maria and three kids named Joanne, Julia, and Andrew. Jack subtly changes the family vacation from a lazy week of Mediterranean fun and sun in Corfu, Greece, to a tour of India, because of a story he has to cover. Maria is not as impressed by this as the kids are. Jack himself envisioned a chance to simultaneously work an easy reporting assignment and spend a little quality time with his family. But on the way to India, the airplane, a 747 owned by AM Air, an American airline, makes an unscheduled stopover in Limassol Cyprus, because of a mechanical problem. After a while of waiting inside the Limassol airport, everyone gets back on the plane -- which is then hijacked by a group of terrorists known as the August 15th Movement, led by a Serbian man named Ivanic Loyvek and his right-hand man Karadan Maldic. The terrorists take a silver briefcase from an diplomatic courier, an older man, and it appears to be an important object of their hijack. And they are demanding $50,000,000 from the US State Department in one hour, or everyone on the airplane will die.The demand is met, and Loyvek and Maldic start releasing the women and children, with the men to go last. But as soon as a front passenger door is opened, the local police begins shooting. Inside the plane, the owner of the briefcase retrieves it, only to be killed the terrorists, who take it again.The flight attendants frantically open the rest of the airplane's doors and start getting passengers out, but the terrorists start killing passengers, leading to an explosion. Maria, Joanne, and Julia get out of the airplane, and then Jack, holding Andrew, gets out -- only to watch Maria, Joanne, and Julia get shot by the terrorists. Jack tries to hide Andrew's face so he can't see. Maria and Joanne are killed, but Julia burns to death while crying for help.Jack and Andrew survive. 15 passengers die, and Loyvek and Maldic, the surviving terrorists, escape, knowing that they now have the $50,000,000. Back in London, a devastated Jack is told that the terrorists were captured, but they were released and deported secretly, with no charges and no arrest, the result of some awfully compromised politics. Jack is understandably enraged that Loyvek and Maldic got off scot-free. While helping Andrew cope, Jack tries all the legal ways to ensure justice for his family, but to no avail.Jack even pays a visit to Henry Davidson, a CIA agent who works at the American Embassy in London. Davidson tells Jack that there's little that can be done. The American and British governments are completely impotent when it comes to going after Loyvek and Maldic. Jack decides he has no choice in the matter but to seek revenge. With the help of his ex-intelligence operative friend Kate Stockton, who is well-schooled in the finer points of international intelligence, Jack becomes a one-man anti-terrorist squadron, searching for Loyvek and Maldich. He finds a warehouse they apparently are using as a headquarters. Breaking in, he finds some papers which he takes, and some weapons. The terrorists return, find a flashlight Jack was using, and begin searching the warehouse. Jack returns upstairs, retrieves a machine pistol and loads it with a magazine. He kills three terrorists before escaping.He later breaks into the home of a friend at MI6 and steals a Walther PPK pistol from his home. He shows up at a theatre and makes a scene at the bar, to be sure he is noticed by the bartender. He then follows one of the terrorists in his taxicab, killing him with that weapon. He returns to the theatre and makes a point of apologizing to the bartender. The next day he goes pheasant hunting with his MI6 contact in case he is tested for gunpowder residue.Dogging Jack's trail is FBI agent Jules Bernard, who's cooperating with Scotland Yard on anti-terrorist activities, and who suspects
Question: Who does Jack visit? | [
"henry davidson"
] | task469-1bd30f9ff15948b194cd57a6004cbb12 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Call Northside 777 is a 1948 documentary-style film noir directed by Henry Hathaway and starring James Stewart.
Question: What year was Call Northside 777 made? | [
"1948"
] | task469-951578b7cd9347669b63701e2e10ad35 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Disturbance of intracellular trafficking plays a major role in several neurodegenerative disorders including Alzheimer or Parkinson's disease. The Chediak-Higashi syndrome (CHS), a life-threatening autosomal recessive disease with frequent mutations in the LYST gene, and its animal model, the beige mouse, are both characterized by lysosomal defects with accumulation of giant lysosomes. Clinically they manifest as hypopigmentation, abnormal bleeding and increased susceptibility to infection with various degrees of involvement of the nervous system. In the course of a recessive N-ethyl-N-nitrosurea (ENU) mutagenesis screen, we identified the first murine missense mutation in the lysosomal trafficking regulator gene (Lyst(Ing3618)) located at a highly conserved position in the WD40 protein domain. Nearly all described human Lyst alleles lead to protein truncation and fatal childhood CHS. Only four different missense mutations have been reported in patients with adolescent or adult forms of CHS involving the nervous system. Interestingly, the Lyst(Ing3618) model presents with a predominant neurodegenerative phenotype with progressive degeneration and loss of Purkinje cells and lacks severe impairment of the immune system. Therefore, the Lyst(Ing3618 )allele could represent a new model for adult CHS with neurological impairment. It could also provide an important tool to elucidate the role of neuronal lysosomal trafficking in the pathophysiology of neurodegeneration.
Question: Which syndrome is associated with mutations in the LYST gene? | [
"chediak-higashi syndrome"
] | task469-1f22467beb9e42fa98428b78fa3b8d4b | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Seahawks began their 2008 campaign on the road against the Buffalo Bills. In the first quarter, Seattle trailed early as Bills RB Marshawn Lynch got a 21-yard TD run. In the second quarter, the Seahawks continued to struggle as WR/PR Roscoe Parrish returned a punt 63 yards for a touchdown. Seattle responded with QB Matt Hasselbeck completing a 20-yard TD pass to WR Nate Burleson. Buffalo closed out the half with kicker Rian Lindell getting a 35-yard and a 38-yard field goal. In the third quarter, the Seahawks replied with kicker Olindo Mare nailing a 45-yard field goal. However, the Bills pulled a trick play on Seattle. Appearing to go for a 32-yard field goal, Buffalo's holder (punter Brian Moorman) instead threw a 19-yard TD pass to DE Ryan Denney. The Bills pulled away with QB Trent Edwards completing a 30-yard TD pass to TE Robert Royal.
Question: Which player scored the longest play of the game? | [
"roscoe parrish"
] | task469-c762bb5e2c714ef6a873a539a2083b6e | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: In 2006, eighteen-year-old Jamal Malik (Dev Patel) from the Juhu slum, is a contestant on the Indian version of Who Wants to Be a Millionaire? (see Kaun Banega Crorepati), and is one question away from the grand prize. However, before the 20 million (US$300,000) question, he is detained and tortured by the police, who suspect him of cheating because of the impossibility of a simple "slumdog" with very little education knowing all the answers. Jamal recounts, through flashbacks, the incidents in his life which provided him with each answer. Jamal's flashbacks begin with his managing, at age five, to obtain the autograph of Bollywood star Amitabh Bachchan, which his brother Salim then sells, followed immediately by the death of his mother during the Bombay Riots. As they flee the riot, they meet Latika, a girl from their slum. Salim is reluctant to take her in, but Jamal suggests that she could be the third musketeer, a character from the Alexandre Dumas novel (which they had been studying albeit not very diligently in school), whose name they do not know. The three are found by Mamana gangster who tricks and then trains street children into becoming beggars. When Salim discovers Maman is blinding the children in order to make them more effective beggars, he flees with Jamal and Latika to a departing train. Latika fails to board the train as Salim purposefully lets go of her hand, thus resulting in her being recaptured by Maman. Over the next few years, Salim and Jamal make a living travelling on top of trains, selling goods, picking pockets, working as dish washers, and pretending to be tour guides at the Taj Mahal, where they steal people's shoes. At Jamal's insistence, they return to Mumbai to find Latika, discovering that she is being raised by Maman to be a prostitute, to fetch him soon a high price and as a virgin. The brothers rescue her, and while escaping Maman they shoot him to death. Salim then manages to get a job with Javed Maman's rival crime lord. Back at their room, Salim orders Jamal to leave him and Latika alone. When Jamal refuses, Salim draws a gun on him, whereas Latika persuades Jamal to obey his brother and go away. Years later, now a tea-boy in an Indian call centre, Jamal searches the centre's database for Salim and Latika. He fails in finding Latika but succeeds in finding Salim, who is now a high-ranking lieutenant in Javed's crime organisation. Jamal reproaches Salim, who then pleads for forgiveness, and offers him to stay in his luxurious apartment. Jamal later bluffs his way into Javed's residence to reunite with Latika but as he professes his love for her, Latika asks him to forget about her. Jamal nevertheless promises to wait for her every day at five o'clock at the VT station. Latika attempts to meet him there, but is recaptured by Javed's men, led by Salim, and once Javed moves to another house, outside Mumbai, the two again lose contact. Jamal becomes a contestant on Who Wants to Be a Millionaire?, knowing that she watches the show regularly. Much to the consternation of Prem Kumar, the show's host, Jamal becomes a wonder across India. He uses the 50/50 lifeline on the penultimate question and during the following break, whilst in the men's room, Kumar tries to fail Jamal, feeding him with a wrong answer, yet Jamal chose the other one, which turned out to be the correct answer. Assuming Jamal is cheating, the police are involved. After an initial beating up, the police inspector listens to Jamal's explanation of how he reached each answer. Finding all of them "bizarrely plausible", he allows him back to the show. At Javed's safehouse, Latika sees Jamal on the news and Salim, in an effort to make amends for his past behaviour, gives Latika his mobile phone and car keys, and asks her to forgive him and to go to Jamal. Latika is reluctant out of fear of Javed, but agrees and escapes.
Question: What is the name of the show Jamal was on? | [
"who wants to be a millionaire"
] | task469-5e46e34cc95a4adbb0b19c8c75176b9f | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: To describe your location wherever you are on Earths surface, you could use a coordinate system. For example, you could say that you are at 1234 Main Street, Springfield, Ohio. Or you could use a point of reference. If you want to meet up with a friend, you could tell him the distance and direction you are from the reference point. An example is, I am at the corner of Maple Street and Main Street, about two blocks north of your apartment. When studying Earths surface, scientists must be able to pinpoint a feature they are interested in. Scientists and others have a system to describe the location of any feature. Usually they use latitude and longitude as a coordinate system. Lines of latitude and longitude form a grid. The grid is centered on a reference point. You will learn about this type of grid when we discuss maps later in this chapter. When an object is moving, it is not enough to describe its location. We also need to know direction. Direction is important for describing moving objects. For example, a wind blows a storm over your school. Where is that storm coming from? Where is it going? The most common way to describe direction is by using a compass. A compass is a device with a floating needle (Figure 2.1). The needle is a small magnet that aligns itself with the Earths magnetic field. The compass needle always points to magnetic north. If you have a compass and you find north, you can then know any other direction. See the directions, such as east, south, west, etc., on a compass rose. A compass needle lines up with Earths magnetic north pole. This is different from Earths geographic north pole, or true north. The geographic north pole is the top of the imaginary axis around which Earth rotates. The geographic north pole is much like the spindle of a spinning top. The location of the geographic north pole does not change. However, the magnetic north pole shifts in location over time. Depending on where you live, you can correct for the difference between the two poles when you use a map and a compass (Figure 2.2). Some maps have a double compass rose. This allows users to make the corrections between magnetic north and true north. An example is a nautical chart that boaters use to chart their positions at sea (Figure 2.3). As you know, the surface of Earth is not flat. Some places are high and some places are low. For example, mountain ranges like the Sierra Nevada in California or the Andes in South America are high above the surrounding areas. We can describe the topography of a region by measuring the height or depth of that feature relative to sea level (Figure mountains, while others are more like small hills! Relief, or terrain, includes all the landforms of a region. A topographic map shows the height, or elevation, of features in an area. This includes mountains, craters, valleys, and rivers. For example, Figure 2.5 shows the San Francisco Peaks in northern Arizona. Features on the map include mountains, hills and lava flows. You can recognize these features from the differences in elevation. We will talk about some different landforms in the next section. If you take away the water in the oceans (Figure 2.6), Earth looks really different. You see that the surface has two main features: continents and ocean basins. Continents are large land areas. Ocean basins extend from the edges of continents to the ocean floor and into deep trenches. Continents are much older than ocean basins. Some rocks on the continents are billions of years old. Ocean basins are only millions of years old at their oldest. Because the continents are so old, a lot has happened to them! As we view the land around us we see landforms. Landforms are physical features on Earths surface. Landforms are introduced in this section but will be discussed more in later chapters. Constructive forces cause landforms to grow. Lava flowing into the ocean can build land outward. A volcano can be a constructive force. Destructive forces may blow landforms
Question: The terrain of an area, or the difference between high and low points in an area, is known as | [
"relief"
] | task469-7bc4d3f16d324c4db0f6ac3fd6bb9a4d | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: After winning in a close game at home, the Steelers traveled to Cincinnati for Game 2 against the Bengals. The Bengals scored first in the first quarter when Randy Bullock kicked a 35-yard field goal to make it 3-0. They would then make it 10-0 when Andy Dalton found A.J. Green on an 8-yard pass. In the second quarter, Dalton and Green connected again on a 15-yard pass to make it 17-0. The Steelers managed to get on the board before halftime when Chris Boswell put a 30-yard field goal through to make the score 17-3. In the third quarter, the Steelers drew closer when Ben Roethlisberger found Le'Veon Bell on a 35-yard touchdown to make it 17-10. The Bengals moved back ahead by double digits when Randy Bullock kicked a 31-yard field goal to make it 20-10. In the fourth quarter, it was all Steelers when Boswell put up a 37-yard field goal to make it 20-13. Roethlisberger then found Antonio Brown on a 6-yard pass to tie the game up at 20-20. Finally, Boswell was able to seal the victory with a 38-yard field goal to make the final score 23-20. With their sixth straight win over the Bengals, the Steelers improved to 10-2. The victory marks the third time that the Steelers have recorded two different 7+ win streaks within consecutive and separate regular seasons (1975-76, 1994-95). The team also won their 8th straight game against a divisional opponent. With the win, the Steelers began 4-0 in their division for the first time since 2008. The 17-point comeback was the Steelers' largest since they came back from down 17 on December 20, 2015 against the Denver Broncos, and their largest on the road since their 21-point comeback on October 5, 1997 against the Baltimore Ravens.
Question: Who made more field goals, Bullock or Boswell? | [
"boswell"
] | task469-aabc9b40c993468eae9bc287872c1ab8 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Marigold Lexton (Ali Larter), a self-centered and temperamental young American actress, arrives in India expecting to be treated like a star, despite the fact that she has been making nothing but B movie sequels for some time. She is stranded in Goa after the film she was to star in is canceled, and a sympathetic crew member offers her a ride, which brings her to the set of another movie, a Bollywood musical. She actually tells her boyfriend Barry that she was hoping she wouldn't have to marry him if this trip was successful, and soon finds herself the center of attraction on the set, where she quickly lands a minor role and a date with the spoiled young lead actor. But after she rebuffs his crude proposal that night she winds up talking with Prem (Salman Khan), the film's choreographer. He knows she lied about being able to dance, and takes her in hand, while showing her the nearby towns and countryside in their spare time. As they grow closer Prem talks to her about the importance of family, and she not only learns that he is estranged from his father, but that he is also a prince. He had not seen his family in three years, but the day before he received a call from his sister, asking him to come home for her wedding. He asks Marigold to go home with him to Jodhpur, Rajasthan, for the wedding, since shooting on the movie had been shut down for a week. She is entranced by the generosity and opulence of his family leading up to the wedding, but afterwards is shocked to discover that he has been betrothed to another since childhood. He has fallen totally in love with Marigold, but has neglected to mention the long arranged marriage, and his father has not encouraged him to follow his heart. She feels betrayed and storms out, followed by Prem's fiance, who offers to buy her a drink. She confesses to Marigold that although she loves Prem she doesn't believe he has ever really loved her. Meanwhile, Prem, a teetotaler, heads to a bar to drown his sorrows, where he finds a drunken American who commiserates with his romantic problems. He explains he has come looking for his estranged girlfiend, called Marigold, and Prem invites him to stay the night at his parents' house. Barry accepts and then passes out. In the morning, Marigold decides to return with Barry to the United States, since Prem, the only son of Jaipur's Ruler, feels duty bound to marry the woman his father has chosen. The ceremony takes place that day, and as he follows his bride, whose face is totally hidden behind a long veil, seven times around the Holy fire, Prem believes he is marrying the woman he has been engaged to since childhood. With the marriage complete, Prem lifts his wife's veil, and he and most of the guests are astonished to find Marigold standing before himand it appears that Barry has married Prem's former fiance as well. The movie's director and their friends from the crew appear in the crowd, cheering, then Prem sings and dances with Marigold and a full chorus, just like a happy ending in a Bollywood musical.
Question: Marigold arrives in London with no what? | [
"she doesn't"
] | task469-e249a149f5824f7c84a4b4517384d76c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Ravenea rivularis is an endangered species of flowering plant in the Arecaceae family.
Question: What is the iucn conservation status of Ravenea rivularis? | [
"endangered species"
] | task469-155024a280744d6fb15b448615d1376b | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The British Museum Description: The British Museum is a museum in London, which is one of the world's greatest museums of human history and culture. Its collections, which number more than 13 million objects, are amongst the largest and most comprehensive in the world and originate from all continents, illustrating and documenting the story of human culture from its beginning to the present. The British Museum was established in 1753, largely based on the collections of the physician and scientist Sir Hans Sloane. The museum first opened to the public on 15 January 1759 in Montagu House in Bloomsbury, on the site of the current museum building. Its expansion over the following two and a half centuries was largely a result of an expanding British colonial footprint and has resulted in the creation of several branch institutions. Until 1997, when the British Library (previously centered on the Round Reading Room)moved to a new site, the British Museum housed both a national museum of antiquities and a national library in the same building. The museum is a non-departmental public body sponsored by the Department for Culture, Media and Sport. Since 2002 the director of the museum has been Neil MacGregor. Admission and opening hours: The museum is open every day from 10am to 6pm (Fridays 10am to 5:30pm)and it charges no admission fee, except for loan exhibitions. How to get there: By train: 7:00-18:30 every day. By Underground: 8:00-18:30 every day. By bus: 7:30-18:30 every day. By coach: 7:00--19:30 every day. Nearest underground stations: Tottenham Court Road (500m) Holborn (500m) Russell Square (800m)
Question: You are at the Museum at seven in the evening and you want to go back to Oxford. Which means of transportation will you choose? | [
"by coach."
] | task469-6d1252d5ffe944ef8adefa54d25df3bd | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: We have recently heard a great deal about the effects of computers on our social and economic organizations. In industry, computers mean automation , and automation means unemployment. Computers in the prefix = st1 /United Stateshave already begun to take the place of workers whose tasks are simple. The variety of jobs, done only by humans in the past, which the machine can perform more rapidly, accurately and economically, increases with each new generation of computers. If we follow this trend, we will be faced with mass unemployment for all but a handful of highly trained professionals who will be more powerful and overworked than they are now. What can we do about it? It is foolish to dream of making history backwards. We cannot pass laws forbidding the advancement of science and technology. The computing machines are here, and they will grow because engineers want to build them, and politicians want their help in the process of government. In short they will develop and become popular because they enable us to complete tasks that could never before have been done, no matter how many unskilled laborers we might have set to work. Computers will continue to increase our intelligence for just the same reason that engines continue to strengthen our muscles. The question we must ask is not whether we shall have computers or not have computers, but rather, since we are going to have them, how we make the most humane and intelligent use of them.
Question: Which kind of the following persons will be the first to be employed if computers continue to develop? | [
"highly trained professionals."
] | task469-d3da5b0c8d374642851feac49e0abc94 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The site of the battle is located near U.S. Highway 56, about three miles east of Baldwin City, and is partially within Robert Hall Pearson Memorial Park, designated by the state of Kansas in honor of one of Brown and Shore's fighters who gave a handwritten account of the battle. Signs placed throughout the battle site point out where the battle began and ended. Efforts are underway to preserve both the Pearson Memorial Park and the Ivan Boyd Prairie Preserve across the road. In 1970, to commemorate the 100th anniversary of the founding of Baldwin City, Baker University professor and playwright Don Mueller and Phyllis E. Braun, Business Manager, produced a musical play entitled The Ballad Of Black Jack to tell the story of the events that led up to the battle. The Ballad Of Black Jack played as part of the city's Maple Leaf Festival from 1970-83 and again from 2001-05. It also played in nearby Lawrence in 1986 and in 2006 and 2007 as a part of Lawrence's Civil War On The Western Frontier program. In 2012 the National Park Service designated the battlefield a National Historic Landmark.
Question: Which occurred first, the 100th anniversary of the founding of Baldwin City or the National Park Service designated the battlefield a National Historic Landmark? | [
"the 100th anniversary"
] | task469-0e2a0f1aa4d44269b28a4d268faeceeb | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Si Renfa's son Si Jifa escaped and continued independent action in another corner of southwest Yunnan. He sent his younger brother Zhaosai to seek pardon from Ming while at the same time he attacked Ming troops in early 1443. However they were defeated and he was forced to flee to Mong Yang. Zhaosai was kept as a hostage and the Ming retreated from Mong Mao. Seeing that Mong Mao was no longer occupied, Si Jifa returned to his father's base of power and began attacking neighboring tribes once again. The third punitive expedition was led by Wang Ji and launched in March 1443. Although the mission was to capture Si Jifa, negotiations on the return of Si Renfa had fallen ill. Ava demanded Ming territory for itself and Hsenwi in return of Si Renfa. Furthermore Ava had made peace with Si Jifa. Therefore, although the Ming army quickly defeated Si Jifa's base of power and captured his family, Si Jifa managed to escape to Mong Yang, and the Ming army decided not to pursue out of consideration of a combined Ava-Hsenwi attack on Ming forces. A compromise was finally reached between Ava and Ming in April 1445. Ava agreed to hand over Si Renfa in return for Ming support in annexing part of Hsenwi's territory. Si Renfa came into Ming custody in August 1445 and was executed in January 1446.
Question: Where did Si Renfa have a base of power? | [
"mong mao"
] | task469-49171e1e3e0f423ea8856abd8524c701 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Andromeda I was discovered by Sidney van den Bergh in 1970 with the Mount Palomar Observatory 48-inch telescope.
Question: When was Andromeda I found or made? | [
"1970"
] | task469-c91a793747134ada9f8edaf019eb2cab | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Interstitial deletions of chromosome band Xq26.3 are rare. We report on a 2-year-old boy in whom array comparative genomic hybridization analysis revealed an interstitial 314 kb deletion in Xq26.3 affecting SLC9A6 and FHL1. Mutations in SLC9A6 are associated with Christianson syndrome (OMIM 300243), a syndromic form of X-linked mental retardation (XLMR) characterized by microcephaly, severe global developmental delay, ataxia and seizures. FHL1 mutations cause Emery-Dreifuss muscular dystrophy (OMIM 310300), X-linked myopathy with postural muscle atrophy (XMPMA, OMIM 300696), scapuloperoneal myopathy (OMIM 300695), or reducing body myopathy (OMIM 300717, 300718). The clinical problems of the patient reported here comprised severe intellectual disability, absent speech, ataxia, epilepsy, and gastroesophageal reflux, and could mostly be attributed to SLC9A6 insufficiency. In contrast to the majority of reported Christianson syndrome patients who were microcephalic, this patient was normocephalic, but his head circumference had decelerated from the 50th centile at birth to the 25th centile at the age of 2 / years. Muscle problems due to the FHL1 deletion are not to be expected before late childhood, which is the earliest age of onset for FHL1 associated Emery-Dreifuss muscular dystrophy. This patient broadens the spectrum of SLC9A6 mutations and contributes to the clinical delineation of Christianson syndrome. This is also the first patient with a deletion affecting both SLC9A6 and the complete FHL1 gene.
Question: Mutation of which gene is implicated in the Christianson syndrome? | [
"slc9a6"
] | task469-8edef0afb41c4d1fb3bb18b0b364f406 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The military aspect of the war began with the Armistice of Mudros. The military operations of the Greco-Turkish war can be roughly divided into three main phases: the first phase, spanning the period from May 1919 to October 1920, encompassed the Greek Landings in Asia Minor and their consolidation along the Aegean Coast. The second phase lasted from October 1920 to August 1921, and was characterised by Greek offensive operations. The third and final phase lasted until August 1922, when the strategic initiative was held by the Turkish Army.
Question: Which happened first, the Armistice of Mudros, or the Greek offensive operations? | [
"armistice of mudros"
] | task469-0d8a0cae5da641e290e761ebfaebe22c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Salt Flat Utah, 1873. Stubby Preston (Fabio Testi) a card-shard and gambling trickster, arrives in the small Wild West town to practice his art at the local casino. However, the town sheriff (Donald O'Brien) recognizes him climbing out of the stagecoach and within minutes, he is in a jail cell for the night and his marked cards are burned. Stubby's cell-mates are Emmanuelle 'Bunny' O'Neill (Lynne Frederick) a young prostitute; Bud (Harry Baird), a mentally disturbed black man who is obsessed with the dead; and Clem (Michael J. Pollard), the town drunkard. During the night, a masked posse of men wreck havoc throughout the settlement. Fearing for their safety as the massacre progresses, the prisoners demand to be realeased, but the sheriff refuses. The following morning, the sheriff, amused by Stubby's ways, allows them to leave town, pointing them to an abandoned wagon as their means of transportation. The sheriff also tells them that the massacre was all his idea to reclaim the town from lawlessness.The four released convicts decide to travel together, and Stubby takes a liking to Bunny. As they travel, aiming to his the next big town over 200 miles away, a friendship develops between the four reprobates. During their first stop for the night, Bunny reveals that she's eight months pregnant, having gotten knocked up by a client in Salt Flat and has been hiding it with oversized dresses. The following day, the four have an encounter with a group of Christian missionaries from Switzerland where Stubby has Bunny pose as his wife, who's happy about the charade.Afterwards, the four's idyll is interrupted by appearance of a Mexican sharpshooter called Chaco (Tomas Milian). Despite initial suspicious, he is welcomed into the group. Chaco displays his shooting skills by shooting rabbits and ducks for their meal for the night. But he shows a sinister side when the group is attacked by three posse members from Salt Flat, and Chaco gleefully shoots all three of them, and sadistically tortures the one surviving posse member. That evening, Chaco persuades the group to take peyote with him. Stubby, secretly spits out the hallucinogenic cactus, suspicious alerted, but the rest of the party accepts. Chaco then amuses himself with Clem, humiliating the drug-addled alcoholic by ordering that he crawl and bark like a dog for some liquor. When Stubby attempts to make a run for it, Chaco subdues him and ties up the four travelers at gunpoint. As day breaks, Chaco rapes Bunny despite seeing her condition. Stubby swears to kill Chaco one day if he survives. The evil bandit then rides off on the wagon with all their gear, leaving them tied up in the desert, except for Clem who he shoots in the leg. Clem frees the others and they continue their trek on foot. As Clems wound worsens, Stubby is forced to remove the bullet and he and Bud carry him on a makeshift stretcher. Later, the group comes upon the aftermath of another attack by Chaco and two henchmen. The Christian wagoners, children and all, have all been slaughtered.The group's journey continues. Eventually the four friends see buildings ahead. The arrive in a small town in the pouring rain, but discover that it's a ghost town. The following morning is bright and sunny. Bud is ecastic when he discovers a graveyard full of friends to talk to. That evening, Clem gets more sicker from the infection of his wound. But he makes dying request that Stubby and Bunny to get married. The couple profess their love for one another and they kiss for the first time. The next morning, the couple decide to leave the ghost town. Bud elects to stay behind having learned to hunt animals for food. But Stubby and Bunny discover Clems mutilated dead body and learn that Bud has taken a liking to cannibalism as well. Stubby and Bunny leave Bud and his 'city of the dead' and head on out.A little later, the couple run into another one of Stubby's old acquaintances, the pseudo-Reverend Sullivan (Adolfo Lastretti). Stopping for
Question: Who is operated on and dies from his wounds? | [
"clem"
] | task469-c8ba9a821e13462786fe72cc9ba5633f | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Topographic maps represent the locations of geographical features, such as hills and valleys. Topographic maps use contour lines to show different elevations. A contour line is a line of equal elevation. If you walk along a contour line you will not go uphill or downhill. Topographic maps are also called contour maps. The rules of topographic maps are: Each line connects all points of a specific elevation. Contour lines never cross since a single point can only have one elevation. Every fifth contour line is bolded and labeled. Adjacent contour lines are separated by a constant difference in elevation (such as 20 ft or 100 ft). The difference in elevation is the contour interval, which is indicated in the map legend. Scales indicate horizontal distance and are also found on the map legend. Old Faithful erupting, Yellowstone Na- tional Park. While the Figure 1.1 isnt exactly the same view as the map at the top of this concept, it is easy to see the main features. Hills, forests, development, and trees are all seen around Old Faithful. A bathymetric map is like a topographic map with the contour lines representing depth below sea level, rather than height above. Numbers are low near sea level and become higher with depth. Kilauea is the youngest volcano found above sea level in Hawaii. On the flank of Kilauea is an even younger volcano called Loihi. The bathymetric map pictured in the Figure 1.2 shows the form of Loihi. Loihi volcano growing on the flank of Kilauea volcano in Hawaii. Black lines in the inset show the land surface above sea level and blue lines show the topography below sea level. A geologic map of the region around Old Faithful, Yellowstone National Park. A geologic map shows the geological features of a region (see Figure 1.3 for an example). Rock units are color- coded and identified in a key. Faults and folds are also shown on geologic maps. The geology is superimposed on a topographic map to give a more complete view of the geology of the region. Click image to the left or use the URL below. URL:
Question: this type of map shows rock units and features like faults and folds. | [
"geologic map"
] | task469-bcb179b805064c8fba40556a68baa012 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The spin-off movie focuses on Matt Stifler (Tad Hilgenbrinck), the younger brother of Steve Stifler from the previous American Pie films. Matt is eager to enter the family business of making porno films, so he can prove to his older brother that he is "up to the standards of the Stifmeister." Stifler and his friends play a prank on the band students during the seniors' graduation ceremony by spraying pepper spray on the mouthpieces of the band's instruments. Matt narrowly escapes getting caught and stows the can of pepper spray in his front pocket, which subsequently leaks onto his genitals. The band members begin to play "Pomp and Circumstance", only to become too irritated by the pepper spray to continue. During the commotion, one of the students trips and pulls down the back curtain, which reveals Matt, who is washing his pepper-spray-soaked genitals in a drinking fountain, in front of the whole school.The band leader Elyse Houston (Arielle Kebbel) demands that Stifler be punished for ruining their performance, stating that he always gets away with his pranks because he is the school's star football player. The school's guidance counselor Chuck Sherman ("The Sherminator") (played by Chris Owen from the original American Pie films) decides that a worthwhile punishment would be for Stifler to attend band camp, in the hopes that he would make friends with the "bandies" and not follow in the footsteps of his much-hated brother.When first arriving, Matt is very disrespectful to the rules and also everyone at Tall Oaks and gets his band group in trouble. He is sent to the office of Noah Levenstein (Jim's father) (Eugene Levy), who works as the camp MACRO (Morale and Conflict Resolution Officer; he's filling in for Michelle as she is now pregnant), recommends that he try to fit in and earn the band's trust, which is the last thing that Matt wants to do. However, a phone call from a friend, who says that earning their trust will get him better footage for his video, inspires Matt to be much more respectful and humble towards the band.Matt finds out that his dorky roommate Ernie Kapolwitz (Jason Earles) has an extensive knowledge of spy cameras and technology, so Matt agrees to let him help with the filming, making his first friend at Tall Oaks. As Matt "is earning the band's trust" he gets into a big confrontation with their rival band leader, Brandon Van der Camp (Matt Barr), and even goes as far as to accept a duel challenge made by him, having no idea what a "duel" is.It turns out that a duel is the two performers showing off their music skills, with Brandon playing the snare drum, and Matt playing the triangle. Throughout the majority of the competition it seems that Brandon is the heavy favourite; during Brandon's second round of performing, Matt walks away humiliated. As Brandon is about to be declared the official winner, Matt comes back playing the bagpipes to the tune of 'Play That Funky Music' showing that he is actually a decent player, surprising everyone, including Elyse, who is pleasantly surprised by Matt's performance.As Matt is still recording the various happenings at the camp, he gradually becomes friends with some of the band members from his school. He gains some respect from Ernie after Matt sets him up on a date with tattooed bandmate Chloe (Crystle Lightning). Matt starts falling for Elyse, who is revealed to have been a friend of Matt's in 8th grade but had a falling out after Matt started hanging around with Steve and his friends and acting like The Stifmeister. Matt is eventually caught with his movies, and his once-friends want nothing more to do with him.After another talk with Jim's Dad, Matt comes to realize that his brother is not as great or cool as he once thought and that following in his footsteps is not a good idea, so he deletes all the videos he recorded at band camp. He even enlists the help of the band to help Elyse get the band scholarship that Stifler
Question: Who lost a chance at a scholarship? | [
"elyse"
] | task469-d68fd07468064739afd02003f7480bf9 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Damien Ryan (born 20 September 1979) is an Australian professional basketball player.
Question: Which sport does Damien Ryan practice? | [
"basketball"
] | task469-48aa6a70de444b0ca3f3a169545954c0 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Viaweb was also unusual for being partially written in the Lisp programming language.
Question: What is the programming language for Viaweb? | [
"lisp"
] | task469-e1a1597cde07464f8303fbc624555be5 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Shirley Temple Black, who lifted America's spirit as a bright-eyed child movie star during the Great Depression, peacefully passed away at her California home on Monday evening at 85, surrounded by her family and caregivers. Temple, born on April 23, 1928, started her entertainment career in the early 1930s and was famous by age 6. Temple was 3 when her mother put her in dance school, where a talent scout spotted her and got her in Baby Burlesks, a series of short movies with child actors playing in adult movies. Movie studio directors took notice of her and in 1934 she appeared in the film Stand Up and Cheer! and her song and dance caught people's attention. Movies such as Little Miss Marker and Bright Eyes featured her signature song. In 1935, she received a special Oscar for her "outstanding contribution to screen entertainment" in the movie Stand Up and Cheer! She made some 40 feature movies, including The Little Colonel, Poor Little Rich Girl, Heidi and Rebecca of Sunnybrook Farm, in 10 years, starring with big-name actors like Randolph Scott, Lionel Barrymore and Jimmy Durante. Temple was a superstar before the term was invented. She said she was about 8 when crowds shouting their love for her made her realize she was famous. "I wondered why," she recalled. "I asked my mother and she said, 'Because your films make them happy.' " Her child career came to an end at 12. She tried a few roles as a teenager--including opposite future president Ronald Reagan in That Hagen Girl - but retired from the screen in 1949 at 21. Temple was only 17 when she married for the first time to John Agar, who would eventually appear with her in two movies. Their five-year marriage produced a daughter. In 1950 she wed Charles Black in a marriage that lasted until his death in 2005. She and Black had two children. Temple's interest in politics was sparked in the early 1950s when her husband was called back into the Navy to work in Washington.
Question: For which movie did Shirley Temple win the Oscar? | [
"stand up and cheer"
] | task469-c5e66dfbdbe34a6fa35a4b233e63f0d5 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Look at the circle graph in the Figure 1.1. It shows that oil is the single most commonly used energy resource in the U.S., followed by natural gas, and then by coal. All of these energy resources are nonrenewable. Nonrenewable resources are resources that are limited in supply and cannot be replaced as quickly as they are used up. Renewable resources, in contrast, provide only 8 percent of all energy used in the U.S. Renewable resources are natural resources that can be replaced in a relatively short period of time or are virtually limitless in supply. They include solar energy from sunlight, geothermal energy from under Earths surface, wind, biomass (from once-living things or their wastes), and hydropower (from running water). People in the U.S. use far more energyespecially energy from oilthan people in any other nation. The bar graph in the Figure 1.2 compares the amount of oil used by the top ten oil-using nations. The U.S. uses more oil than several other top-ten countries combined. If you also consider the population size in these countries, the differences are even more stunning. The average person in the U.S. uses a whopping 23 barrels of oil a year! In comparison, the average person in India or China uses just 1 or 2 barrels of oil a year. Q: How does the use of oil and other fossil fuels relate to pollution? A: Greater use of oil and other fossil fuels causes more pollution.
Question: the most commonly used energy resource in the u.s. is | [
"oil."
] | task469-ce95f58fcb6647058ff52b4eeaa9680a | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The film starts on June 16, 1994 with Jesse meeting Celine on a train from Budapest and striking up a conversation with her. Jesse is going to Vienna to catch a flight back to the United States, whereas Celine is returning to university in Paris after visiting her grandmother. When they reach Vienna, Jesse convinces Celine to disembark with him, saying that 10 or 20 years down the road, she might not be happy with her marriage and might wonder how her life would have been different if she had picked another guy, and this is a chance to realize that he himself is not that different from the rest; in his words, he is "the same boring, unmotivated guy." Jesse has to catch a flight early in the morning and does not have enough money to rent a room for the night, so they decide to roam around in Vienna. After visiting a few landmarks in Vienna, they share a kiss at the top of the Wiener Riesenrad at sunset and start to feel a romantic connection. As they continue to roam around the city, they begin to talk more openly with each other, with conversations ranging from topics about love, life, religion, and their observations of the city. Celine tells Jesse that her last boyfriend broke up with her six months ago, claiming that she "loved him too much". When questioned, Jesse reveals he had initially come to Europe to spend time with his girlfriend who was studying in Madrid, but they had broken up when she was avoiding him while he was there. He decided to take a cheap flight home, via Vienna, but it did not leave for two weeks so he bought a Eurail pass and traveled around Europe. When they are walking alongside the Donaukanal (Danube canal) they are approached by a man who, instead of begging, offers to write them a poem with a word of their choice in it. Jesse and Celine decide on the word "milkshake", and are soon presented with the poem Delusion Angel (written for the film by the poet David Jewell). In a traditional Viennese cafe, Jesse and Celine stage fake phone conversations with each other, playing each other's friends they pretend to call. Celine reveals that she was ready to get off the train with Jesse before he convinced her. Jesse reveals that after he broke up with his girlfriend, he bought a flight that really was not much cheaper, and all he really wanted was an escape from his life. They admit their attraction to each other and how the night has made them feel, though they understand that they probably will not see each other again when they leave. They simply decide to make the best of what time they have left, ending the night with the implication of a sexual encounter between them. At that point, Jesse explains that if given the choice, he would marry her instead of never seeing her again. The film ends the next day at the train station, where, just as Celine's train is about to leave, the couple decides not to exchange any contact information but instead to meet at the same place in six months.
Question: Where is the train traveling to? | [
"vienna"
] | task469-cd64907ee1814ee4a2cbf7951e168a64 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Browns were making their first trip to San Diego since 2006. The game was back and forth, with neither team leading by more than one possession. The Chargers led 7-3 after the 1st quarter. On the Browns' first drive of the second quarter, QB Josh McCown threw a 34-yard touchdown pass to RB Duke Johnson to put the Browns up 10-7. The teams traded field goals, making it a 13-13 game at halftime. The Browns scored a field goal at the start of the 3rd quarter to go up 16-13. On the Chargers' next drive, QB Philip Rivers led the Chargers to a touchdown, going up 20-16 heading into the 4th quarter. After K Travis Coons kicked a field goal to cut the deficit to 20-19, Rivers led another touchdown drive to put the Chargers up 27-19. On the Browns' next drive, they reached the end zone, assisted by an incredible catch by TE Gary Barnidge on the Chargers' 1 yard line. They converted on the two point conversion to tie the game at 27-27 with just over 2 minutes remaining. The Chargers reached the Browns' 24 yard line with under 50 seconds to play. The Browns began to use timeouts until the Chargers faced 4th down with 2 seconds to play. After the Chargers called timeout, their kicker had an opportunity to win the game with a 39-yard field goal. The 39 yard game winning attempt was off to the right, and the game appeared to be on its way to overtime.. However, CB Tramon Williams was flagged for being offside during the play, giving the Chargers another attempt, this time from 34 yards. The field goal was converted, and the Chargers won 30-27. The Browns committed 12 penalties in the game, including this critical offside penalty.
Question: A field goal from an unknown distance was made by who? | [
"travis coons"
] | task469-1062d306035f4a37859845722760034f | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: After two close losses the Rams hoped to bounce back at the Edward Jones Dome for their first win of the season. On the first possession the Rams drove down the field and capped off their drive with a 41-yard touchdown run by Steven Jackson. On the ensuing Redskins drive, Donovan McNabb drove into Rams territory before Na'il Diggs forced a fumble on Santana Moss. James Butler, who was playing for an injured Craig Dahl picked up the fumbled and returned it 49yards before being forced out of bounds. Bradford threw a three-yard touchdown pass to Daniel Fells to make the score 14-0. The Redskins tried to start their offense again, but after being stopped on third down had to punt. Graham Gano's punt was blocked however by Rams rookie wide receiver Dominique Curry, and the Rams took over in striking distance for another touchdown. Sam Bradford threw his first interception of the day, and the Redskins were able to take over again, and were able to score a field goal. On the kickoff after the Redskins field goal, Mardy Gilyard, the Rams rookie kick returner/wide receiver fumbled the ball, and the Redskins took over on the 21yard line. Donovan McNabb hit Santana Moss for a touchdown the next play. Steven Jackson was injured on the next drive for the Rams, and the Rams were unable to score. The next drive the Redskins kicked another field goal to make the score 13-14. The Rams marched down the field one last time, but were stalled in the redzone. With 31seconds left Josh Brown attempted a field goal, but the Redskins blocked the kick and at the half the Rams led 14-13. At the start of the second half, McNabb hit Moss for a 56-yard pass. The Rams kept the Redskins out of the endzone, and Washington settled for the go ahead field goal to make the score 16-14. The next drive St. Louis marched down the field, and Kenneth Darby, playing for an injured Steven Jackson scored his first TD of the year from 12yards out to make the score 21-16. Redskins were unable to score during the fourth quarter however, and McNabb was picked off by Bradly Fletcher as he attempted a comeback. Josh Brown kicked three field goals in the final quarter to seal the Rams first victory of the year with a score of 30-16, snapping a 13-game home losing skid. This win also marked their highest scoring performance in a regular season game since their 34-14 victory over the Dallas Cowboys on October 19, 2008.
Question: Which team turned the ball over first? | [
"redskins"
] | task469-2929d366905a4fb0af29e5baf28965d4 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The film was nominated for the Academy Award for Best Picture, as well as Art Direction (Carroll Clark and Van Nest Polglase), Original Song (Irving Berlin for ''Cheek to Cheek''), and Dance Direction (Hermes Pan for ''Piccolino'' and ''Top Hat'').
Question: What award was Top Hat nominated for? | [
"academy award for best picture"
] | task469-d2e02402fc6f449faaa491019161bded | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: A volcanic eruption in Iceland has sent ash across northern Europe. Airlines have stopped or changed the flights across the Atlantic Ocean, leaving hundreds of passengers stuck in airports. Grimsvotn is one of the largest and most active volcanoes in Europe. What makes Grimsvotn different is that it lies under a huge glacier of ice up to 12 metres thick. The hot volcano heats up the ice above it, which then forms a layer of water between glacier and the volcano, keeping it stable. As the water flows out from under the glacier, the pressure lifts. The lava from the volcano then comes up to the surface. This is exactly what is happening today. Now airlines have to make changes to their flights so as not to fly through the clouds of volcanic ash. According to KLM, one of Europe's biggest airlines, airplanes cannot go under the cloud or over it. Going through the cloud can result in ash getting stuck in the airplane's engines, causing damage to the plane. The eruption has also caused problems for animals in Iceland. The volcano left ash and sharp, glass-like rocks all over the countryside. Farmers are keeping their animals inside to stop them eating ash-covered grass or the sharp objects.
Question: how many passengers were forced to stay in the airport? | [
"hundreds of passengers"
] | task469-c8edac5608f4429abd5261b43a9cd821 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The human endoplasmic reticulum aminopeptidase (ERAP) 1 and 2 proteins were initially identified as homologues of human placental leucine aminopeptidase/insulin-regulated aminopeptidase. They are categorized as a unique class of proteases based on their subcellular localization on the luminal side of the endoplasmic reticulum. ERAPs play an important role in the N-terminal processing of the antigenic precursors that are presented on the major histocompatibility complex (MHC) class I molecules. ERAPs are also implicated in the regulation of a wide variety of physiological phenomena and pathogenic conditions. In this review, the current knowledge on ERAPs is summarized.
Question: Which is the subcellular localization of ERAP2? | [
"luminal side of the endoplasmic reticulum"
] | task469-524f68dc4d86401f88872a9a7282bb92 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: A specialized nucleotide excision repair pathway known as transcription-coupled repair (TCR) counteracts the toxic effects of DNA damage in transcriptionally active genes. The clustering of active genes into gene-rich chromosomal domains predicts that the sites of TCR are unevenly distributed through the genome. To elucidate the genomic organization and chromosomal localization of TCR, we isolated DNA fragments encompassing TCR-mediated repair sites from UV-C irradiated xeroderma pigmentosum group C cells, which can only repair the transcribed strand of active genes. This DNA was used as a molecular probe to visualize TCR in normal metaphase spreads by reverse fluorescence in situ hybridization. Whereas DNA repair sites in normal human cells are evenly distributed through the genome, TCR is highly localized at specific chromosomal domains. Particularly, clusters of TCR sites were identified at early-replicating gene-rich bands and telomeric regions of several chromosomes. High gene-density chromosomes such as chromosome 19 and the GC-rich domains of several chromosomes (T bands) are preferential locations of TCR. Our results demonstrate that the intragenomic localization of TCR resembles the uneven distribution of the human transcriptome, CpG islands, and hyperacetylated histones, enforcing the basic link between DNA repair, transcription, and nuclear organization in a complex genome.
Question: Which gene strand is targeted by transcription-coupled repair (TCR)? | [
"the transcribed strand"
] | task469-ff77d2a48c394597b0568df8b5ed2293 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Coming off their home win over the Rams, the Bengals flew to Bill Walsh Field at Monster Park for a Saturday night interconference duel with the San Francisco 49ers. After a scoreless first quarter, Cincinnati trailed early in the second quarter as 49ers QB Shaun Hill got a 3-yard TD run. Afterwards, the Bengals would take the lead as kicker Shayne Graham managed to get a 24-yard field goal, while QB Carson Palmer completed a 52-yard TD pass to WR Chris Henry. San Francisco would end the half with Hill completing a 17-yard TD pass to TE Vernon Davis. In the third quarter, the 49ers increased their lead with kicker Joe Nedney getting a 29-yard and a 38-yard field goal. In the fourth quarter, Cincinnati tried to respond as Graham kicked a 35-yard field goal. However, the 49ers' defense held on for the win. With the loss, the Bengals fell to 5-9, securing Head Coach Marvin Lewis' first losing season with Cincinnati.
Question: Who is the Bengals quarterback? | [
"carson palmer"
] | task469-069de9a56aaf4018ac88c7bf0e71c355 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: New England, the late 1950s. Todd Anderson (Ethan Hawke), a lonely and painfully shy teenager, who is under pressure by his stern parents because he must live up to his older brother's reputation to attend Yale and become a lawyer, arrives for the new semester at the Welton Academy for boys -- Todd's brother also attended Welton and was a popular and well-regarded student there. This semester begins during an orientation gathering with a speech given by the stern Headmaster Nolan (Norman Lloyd), who states the academy's four pillars: Tradition, Honor, Discipline, and Excellence. Todd meets Neil Perry (Robert Sean Leonard) an ambitious student whom becomes his dorm roommate.Later in his dorm, Neil is ordered by his grumpy and domineering father (Kurtwood Smith) to drop his involvement with the school annual in order to maintain good grades so the boy may become a doctor much as he has done. Neil is under pressure from his stern father's will. Also, Mr. Perry tells Neil that Mrs. Perry also wants him to become a doctor, which further worries the boy. A little later, Todd tells Neil that he is in a similar situation with his parents involving his older brother who also attended Welton a few years ago, graduated, and attended Yale Law School and became a lawyer and his parents want the exact same thing for him. But Todd does not have the courage to tell his parents that he instead wants to be a writer, not a lawyer.During the first day of classes Todd and Neil experience the various teaching methods which include speeches by the trig teacher, as well as the Latin teacher, and the math teacher who states that "all 20 questions at the end of the first chapter are due tomorrow". In stark contrast to these orthodox teaching methods, the guys see a different side of the school when they attend English class taught by the newly arrived (and liberal-minded) Mr. Keating (Robin Williams), whom they met briefly during the orientation -- Keating tells his class he was also a student at Welton ("Helton" as the students secretly refer to the institution) himself many years ago. Keating enters his class whistling the 1812 Overture, and he first takes the boys out in the hallway to the school's displays cases containing artifacts of the school's sports achievements. He tells them that they all have the potential to become powerful individuals, and they are responsible for what their futures will hold. These two actions show his difference from the other teachers because no other teacher would commit the actions he does. Also, he tells the boys they may call him "Oh Captain, my Captain", if they dare. These examples of Mr. Keating's teachings show the boys how to think for themselves. Mr. Keating then tells the boys "Carpe Diem", which is Latin for "seize the day".In addition to Todd and Neil, a small group of other students whom include the lovesick Knox Overstreet (Josh Charles), the flip Charlie Dalton (Gale Hansen), the pragmatic Richard Cameron (Dylan Kussman), liberal Steven Meeks (Allelon Ruggiero) and the moderate Gerard Pitts (James Waterston), also react to the first day's lesson with comments from "that was weird" to "neat". Cameron asks if anything Keating told them will be on a future test and the boys respond with mild scorn.The next day Keating starts the class with a traditional teaching approach by having Neil read out loud the introduction to their poetry textbook, which describes how to rate the quality of poetry according to mathematical plotting. Keating finds such mathematical criticism ridiculous and instructs his pupils to rip out the essay which is one of three ways that he demonstrates freedom of expression and non-conformity. When some students hesitate, he tells them "this is not the Bible. This is a battle, a war. You will have to learn to think for yourselves." He later has the students stand on his desk as a reminder to look at the world in a different way.A few days later, Knox Overstreet is asked to attend a dinner party at the Danburry
Question: Who was attracted by the new english teacher's methods? | [
"the students",
"todd and neil, and a small group of other students"
] | task469-4e1f07c1106d4d55aba46cf1c23856ac | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Percy Dobell (29 April 1864 -- 5 January 1903) was an English cricketer active from 1886 to 1887 who played for Lancashire.
Question: When is the date of birth of Percy Dobell? | [
"29 april 1864"
] | task469-03cf4001c8794fbeb801bb987958b93d | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The following are selected contributors' notes for an essay collection. KATY BUTLER, a 2004 finalist for a National Magazine Award, has written for The New Yorker, the New York Times, Mother Jones, Salon, Tricycle, and other magazines. She was born in South Africa and raised in England, and came to the United States with her family at the age of eight. "Everything Is Holy," her essay about nature worship, Buddhism , and ecology, was selected for Best Buddhist Writing 2006. In 2009 she won a literary award from the Elizabeth George Foundation. "What Broke My Father's Heart" was named a "notable narrative" by the Nieman Foundation for Journalism at Harvard, won a first-place award from the Association of Health Care Journalists, and was named one of the 100 Best Magazine Articles of All Time. Butler has taught narrative nonfiction at Nieman Foundation conferences and memoir writing at Esalen Institute. Her current book project is Knocking on Heaven's Door: A Journey Through Old Age and New Medicine to be published in 2013. VICTOR LAVALLE is the author of a collection of stories, Slapboxing with Jesus, and two novels, The Ecstatic and Big Machine, for which he won the Shirley Jackson Award, the American Book Award, and the Ernest J. Gaines Award for Literary Excellence. He is a 2010 Guggenheim Award winner and an assistant professor at Columbia University's School of the Arts. About "Long Distance" he says: "This essay actually came about when I was asked to write about my life after having lost a great deal of weight. And yet, when I sat down to work, all I could do was return to that time when I was much heavier and deeply unhappy. Why? I sure didn't miss those days. And yet, I felt I couldn't write about my present without touching on that past. But, of course, I never reach the true present in the essay. Maybe I still don't know how to talk about a life with greater happiness. " BRIDGET POTTER was born in Brompton-on-Swale, Yorkshire, and came to the United States as a teenager in 1958. She spent the first forty years of her career in television, beginning as a secretary, then as a producer and an executive, including fifteen years as senior vice president of original programming at HBO. In 2007 she earned a BA in cultural anthropology from Columbia University. This year she will complete an MFA in nonfiction, also from Columbia, where she has been an instructor in the University Writing Program. She is currently working on her first book, a memoir / social history of the 1960s, from which her essay "Lucky Girl" is adapted. PATRICIA SMITH is the author of five books of poetry, including Blood Dazzler, chronicling the tragedy of Hurricane Katrina, which was a finalist for the 2008 National Book Award, and Teahouse of the Almighty, a National Poetry Series selection. Her work has appeared in Poetry, The Paris Review, TriQuarterly, and The Best American Poetry 2011. She is a Pushcart Prize winner and a four-time individual champion of the National Poetry Slam, the most successful poet in the competition's history. RESHMA MEMON YAQUB wouldn't even be fit to write a grocery list were it not for her guardian editors. Her stories owe many glorious plot twists to Zain, eleven, and Zach, seven. Ditto their dad (Amer) and grandparents (Ali, Razia, Muhammad, Nasreen). Costars: Sophie, Sana, Yousef, and Maryam. Miss Yaqub lives in Bethesda, Maryland. Her next project is an investigation into the whereabouts of two missing people: Mr. Right and Ms. Memoir Literary Agent.
Question: Who is the most successful poet in the competition's history? | [
"patricia smith."
] | task469-9c38984739a54beba4d9df2f336f088c | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Nuclear fission is the splitting of the nucleus of an atom into two smaller nuclei. This type of reaction releases a great deal of energy from a very small amount of matter. For example, nuclear fission of a tiny pellet of uranium-235, like the one pictured in Figure 11.11, can release as much energy as burning 1,000 kilograms of coal! Nuclear fission of uranium-235 can be represented by this equation: 235 92 U + 1 141 Neutron !92 36 Kr + 56 Ba + 3 Neutrons + Energy As shown in Figure 11.12, the reaction begins when a nucleus of uranium-235 absorbs a neutron. This can happen naturally or when a neutron is deliberately crashed into a uranium nucleus in a nuclear power plant. In either case, the nucleus of uranium becomes very unstable and splits in two. In this example, it forms krypton-92 and barium-141. The reaction also releases three neutrons and a great deal of energy. The neutrons released in this nuclear fission reaction may be captured by other uranium nuclei and cause them to fission as well. This can start a nuclear chain reaction (see Figure 11.13). In a chain reaction, one fission reaction leads to others, which lead to others, and so on. A nuclear chain reaction is similar to a pile of wood burning. If you start one piece of wood burning, enough heat is produced by the burning wood to start the rest of the pile burning without any further help from you. You can see another example of a chain reaction at this URL: If a nuclear chain reaction is uncontrolled, it produces a lot of energy all at once. This is what happens in an atomic bomb. If a nuclear chain reaction is controlled, it produces energy more slowly. This is what occurs in a nuclear power plant. The reaction may be controlled by inserting rods of material that do not undergo fission into the core of fissioning material (see Figure 11.14). The radiation from the controlled fission is used to heat water and turn it to steam. The steam is under pressure and causes a turbine to spin. The spinning turbine runs a generator, which produces electricity. In the U.S., the majority of electricity is produced by burning coal or other fossil fuels. This causes air pollution, acid rain, and global warming. Fossil fuels are also limited and may eventually run out. Like fossil fuels, radioactive elements are limited. In fact, they are relatively rare, so they could run out sooner rather than later. On the other hand, nuclear fission does not release air pollution or cause the other environmental problems associated with burning fossil fuels. This is the major advantage of using nuclear fission as a source of energy. The main concern over the use of nuclear fission is the risk of radiation. Accidents at nuclear power plants can release harmful radiation that endangers people and other living things. Even without accidents, the used fuel that is left after nuclear fission reactions is still radioactive and very dangerous. It takes thousands of years for it to decay until it no longer releases harmful radiation. Therefore, used fuel must be stored securely to people and other living things. You can learn more about the problem of radioactive waste at this URL: Nuclear fusion is the opposite of nuclear fission. In fusion, two or more small nuclei combine to form a single, larger nucleus. An example is shown in Figure 11.15. In this example, two hydrogen nuclei fuse to form a helium nucleus. A neutron and a great deal of energy are also released. In fact, fusion releases even more energy than fission does. Nuclear fusion of hydrogen to form helium occurs naturally in the sun and other stars. It takes place only at extremely high temperatures. Thats because a great deal of energy is needed to overcome the force of repulsion between positively charged nuclei. The suns energy comes from fusion in its core, where temperatures reach millions of Kelvin (see Figure 11.16). Scientists are searching for ways to create controlled nuclear fusion reactions on Earth. Their goal is develop nuclear fusion power plants, where the energy from fusion of hydrogen nuclei can be converted to electricity. How this might work
Question: process in which one nuclear reaction leads to others | [
"nuclear chain reaction"
] | task469-cda2e6394add463597fa937fc2694860 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Avid Free DV is a non-linear editing video editing software application which was made by Avid Technology.
Question: Who is originally behind the development of Avid Free DV? | [
"avid technology"
] | task469-138f449ccf9d421bbce614768f91b1d1 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Every immigrant leads a double life. Every immigrant has a double identity and a double vision, being suspended between an old and a new home, an old and new self. The very notion of a new home, of course, is in a sense as impossible as the notion of new parents. Parents are who they are; home is what it is. Yet home, like parentage, must be legitimized through love; otherwise, it is only a fact of geography or biology. Most immigrants to America found their love of their old homes betrayed: they did not really abandon their countries; their countries abandoned them. In America, they found the possibility of a new love, the chance to nurture new selves. Not uniformly, not without exceptions. Every generation has its Know-Nothing movement. Its understandable fear and hatred of alien invasion is as true today as it always was, but in spite of all this, the American attitude remains unique. Throughout history, exile has been a disaster; America turned it into a triumph and placed its immigrants in the center of a national epic. The epic is possible because America is an idea as much as it is a country. America has nothing to do with loyalty to a dynasty and very little to do with loyalty to particular place, but everything to do with loyalty to a set of principles. To immigrants, those principles are especially real because so often they were absent or violated in their native lands. It was no accident in the '60 and '70s, when alienation was in flower, that it often seemed to be "native" Americans who felt alienated, while aliens or the children of aliens upheld the native values. The immigrant's double vision results in a special, somewhat skewed perspective on America that can mislead but that can also find revelation in the things that to native Americans are obvious. Psychiatrist Robert Coles speaks of those "who straddle worlds and make of that very experience a new world." "Home is where you are happy." Sentimental, perhaps, and certainly not conventionally patriotic, but is appropriate for a country that wrote the pursuit of happiness into its founding document. That continues for the immigrant in America, and it never stops, but it comes to rest at a certain moment. The moment is hard to pin down, but it occurs perhaps when the immigrant's double life and double vision joint together toward a single state of mind. When the old life, the old home fade into a certain unreality: places one merely visits, in fact or in the mind, practicing the tourism of memory. It occurs when the immigrant learns his ultimate lesson: above all countries, America, if loved, returns love.
Question: What can be the best title of the passage? | [
"home is where you are happy"
] | task469-ba5b267120c642cb9c59b0084abbd973 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Baghdad, in 2004, three soldiers of an Army bomb-disposal unit are investigating a report of an improvised explosive device (IED). They use a sophisticated robot drone to examine the device, which consists of several undetonated artillery shells wired together and hidden under plastic/fabric sheets. The unit, led by Sgt. Thompson, decides that they can detonate the IED using plastic explosives that they'll activate from a safe distance. Thompson also says that the explosion won't cause very much property damage and should result in no loss of life.A small cart is affixed to the back of the robot, which is then sent back into the blast zone. Before it can reach the IED, the trailer loses a wheel. Thompson dresses in a bulky bomb suit and walks down to the trailer. He picks it up and carries it to the IED, rigging it properly. As he walks back, his partners, Sgt. Sanborn and Specialist Eldridge, scan the immediate area for anyone they consider suspicious or who may be in the blast zone. When Thompson is about 25 meters from the bomb, but still in the kill zone, Eldridge notices a man running a butcher shop who is using a cellular phone. Eldridge yells to Sanborn and the specialist begins to run toward the man, ordering him to drop his phone. Sanborn tells Eldridge to shoot the man, who presses a sequence of numbers on the phone. The bomb detonates with Thompson still in the kill zone. The overpressure from the bomb kills Thompson despite the bomb suit; a large splash of blood hits the inside of the clear visor on his helmet.Thompson's body is packed into a coffin for shipment home, Sanborn supervises the procedure. He looks over Thompson's possessions for a few moments before the coffin is sealed. Back at the base, Eldridge is sitting in the rec room when the base psychologist, Lt. Col. Cambridge walks in and asks Eldridge how he's feeling (in the wake of Thompson's death). Eldridge is still clearly upset over the incident; he dry fires his rifle several times, suggesting that if he'd shot the man with the cell phone, Thompson might still be alive.A new leader for the team, Sgt. William James, arrives at the base. Sanborn meets him at his housing unit, where James is taking the plywood covers off his windows. When Sanborn suggests that James keep them on because of mortar shrapnel, James tells him that they won't be any good anyway if a mortar shell crashes in through the unit's roof.The next day the team responds to a report of another IED on a narrow street in the city. After the initial investigation, where they link up with the Army platoon that reported the bomb, James is dressed up in a suit similar to the one Thompson wore previously. As James approaches the bomb site, he tosses a smoke grenade, which agitates Sanborn, who can't see James to instruct him further. James also is uncommunicative with his team members, another factor that Sanborn does not appreciate. James finds an artillery shell buried under a small pile of trash. He disarms it easily, and then notices a secondary wire leading away from it. He uncovers the cable and finds it connects to a junction of six more cables. When James pulls on the junction connector, six more shells are uncovered. Another cable leads to a nearby building. James disarms the six new shells; as he does, he notices a man quickly leaving the building, presumably the bomber. James flashes one of the small detonators from one of the shells and smiles at the man, who vanishes from sight. Back at their Humvee, Sanborn tells James that he needs to communicate more during operations and not treat his duty as if it's a solo act. James brushes his teammate off. James does the same later when he and Sanborn talk while grooming themselves for another day's work in the latrine.The team is again called out for another bomb threat. This time, the bomb is in a car parked in front of a United Nations building. When the building is evacuated, James dons
Question: Who wants to return home and have a son? | [
"sanborn wants to return home and have a son.",
"sanborn"
] | task469-21e866db659b42cdb04cc335e7ba614e | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: If you want to stay young,sit down and have a good think. This is the research finding of a team of Japanese doctors, who say that most of our brains are not getting enough exercise, and as a result,we are ageing unnecessarily soon. Professor Taijiu Matsuzawa wanted to find out why otherwise healthy farmers in northern prefix = st1 /Japanappeared to be losing their ability to think and reason at a ly early age, and how the process of ageing could be slowed down. With a team of partners at Tokyo National University,he set about studying the brain volumes of a thousand people of different ages and various jobs. Computer technology enabled the researchers to get exact measurement of the volume of the front and side sections of the brain,which relate to intellect and feelings,and determine the human character. The back section of the brain,which controls functions like eating or breathing,does not connect with age. One can continue living without intellectual or feeling abilities. Contraction of front and side parts - as cells die off - was observed in some subjects in their thirties, but it was still not obvious in some sixty and seventy year olds. Matsuzawa concluded from his tests that there is a simple cure for the contraction normally connected with age using the brain. The findings show in general conditions that contraction of the brain begins soon among people in the country than in the town. Those are at least at risk,says Matsuzawa,who are lawyers,followed by university professors and doctors. White collar workers doing regular work in government offices are, however,as likely to have shrink as the farm workers,bus drivers and shop assistants. Matsuzawa's findings show that thinking can prevent the brain from shrinking. Blood must flow through a circle properly in the head to supply the fresh oxygen the brain cells need. "The best way to keep good blood movement is through using the brain,"he says. " Think hard and engage in conversation. Don't depend on pocket calculators. "
Question: According to the passage,which people seem to age slower than the others? | [
"lawyers."
] | task469-95c70725d3ab44aa9e5d71c1a4050430 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited cerebrovascular disease due to mutations involving loss or gain of a cysteine residue in the NOTCH3 gene. A cluster of mutations around exons 3 and 4 was originally reported. Identification of pathogenic mutation is important for diagnostic confirmation of the disease, however genetic counselling and testing of relatives at risk is critical in mutation carriers. Mutation analysis of the NOTCH3 gene was performed through direct sequencing in 140 patients with clinical suspicion of CADASIL. Patients underwent genetic counselling pre and post testing. The 2-23 exons containing all EGF-like domains were screened. 14 familial forms of the disease have been identified with 14 different causative mutations in exons 2, 3, 4, 5, 7, 10, 14, 19, 20 and 22 of the NOTCH3 gene; no pathogenetic mutations have been identified in exons 6 and 8; several genetic variations both in coding as well as in intronic regions were identified too. Our data confirm the importance of screening the whole EGF-like domains region of NOTCH3 gene for the molecular diagnosis of CADASIL among the Italian population too. Moreover genetic variants different from loss or gain of a cysteine residue are identified and presented.
Question: Which amino acid residue appears mutated in most of the cases reported with cadasil syndrome? | [
"cysteine"
] | task469-6df9bde04b18495c927ba4509ff6fd4b | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Hoping to increase their winning streak the Patriots flew to Cleveland Browns Stadium for an AFC duel with the Browns. The Browns took the opening kickoff 42 yards, scoring on a 38-yard field goal by Phil Dawson. Sammy Morris fumbled the ensuing kickoff and ex-Patriot Ray Ventrone recovered at the Patriots 19. Two plays later, Peyton Hillis scored on a 2-yard Peyton Hillis touchdown run. After a Patriots three-and-out, the drove to the Patriots 49, but Hillis was stripped by Mayo and Meriweather recovered at the Patriots 36. The Patriots couldn't move the ball though and punted. Early in the fourth quarter, the Patriots marched 79-yards in 11 plays, scoring on Brady's two-yard touchdown pass to Hernandez off of a deflection, trimming the deficit to 10-7. However, Cleveland countered with a 9 play, 60-yard drive, scoring on an 11-yard touchdown run by Chansi Stuckey on an end-around, extending the lead to 17-7. The Patriots drove to the Browns 9, but after catching a 6-yard pass, Gronkowski was stripped at the 3-yard line with Abram Elam recovering at the 2. The Browns took a knee and led 17-7 at halftime. Following a Patriots punt, the Browns marched 72 yards in 10 plays, scoring on a 16-yard touchdown run by Colt McCoy, increasing the Browns lead to a stunning 24-7. The Patriots reached the Browns 49 on their next drive, but a holding penalty on Gronkowski killed the drive as their offensive struggles continued. The Browns marched all the way to the Patriots 20 on their next drive, and Dawson was good on a 38-yard field goal, putting the Browns up 27-7 early in the fourth quarter. The Patriots raced 69 yards in 14 plays on their next drive, scoring when Brady found Hernandez on another 1-yard touchdown pass, trimming the deficit to a manageable 27-14. The Browns reached the 39 in five plays, then Hillis burst through and took off for a 33-yard touchdown run, giving the Browns a 34-14 lead and sealing their shocking win. Hoyer stepped in for Brady on their next drive and was intercepted by Eric Wright on the second play at the Browns 40. After the Browns punted, Hoyer took a knee to end the game.
Question: The Browns took how many yards on the opening kickoff? | [
"42 yards"
] | task469-a4acd7c0ae07471897d27014a9af1eee | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: L-DOPA-induced dyskinesia is a common side effect developed after chronic treatment with 3,4-dihydroxyphenyl-l-alanine (l-DOPA) in Parkinson's disease. The biological mechanisms behind this side effect are not fully comprehended although involvement of dopaminergic, serotonergic, and glutamatergic systems has been suggested. The present study utilizes in vivo amperometry to investigate the impact from unilateral 6-hydroxydopamine lesions and l-DOPA (4 mg/kg, including benserazide 15 mg/kg) -induced dyskinetic behavior on striatal basal extracellular glutamate concentration and potassium-evoked glutamate release in urethane-anesthetized rats. Recordings were performed before and after local L-DOPA application in the striatum. In addition, effects from the 5-HT(1A) receptor agonist (2R)-(+)-8-hydroxy-2-(di-n-propylamino)tetralin hydrobromide (8-OHDPAT; 1 mg/kg) was assessed on glutamate release and on dyskinetic behavior. The results revealed a bilateral 30% reduction of basal extracellular glutamate concentration and attenuated potassium-evoked glutamate release after a unilateral dopamine-depletion in L-DOPA naive animals. In dyskinetic subjects, basal glutamate concentration was comparable to normal controls, although potassium-evoked glutamate release was reduced to similar levels as in drug naive dopamine-lesioned animals. Furthermore, acute striatal L-DOPA administration attenuated glutamate release in all groups, except in the dopamine-lesioned striatum of dyskinetic animals. Co-administration of 8-OHDPAT and L-DOPA decreased dyskinesia in dopamine-lesioned animals, but did not affect potassium-evoked glutamate release, which was seen in normal animals. These findings indicate altered glutamate transmission upon dopamine-depletion and dyskinesia.
Question: Which drug is benserazide usually co-administered with? | [
"l-dopa"
] | task469-7b6bbead9c19478f99ebf7aea1662bbe | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: FC Ekibastuzets are a Kazakhstani football club based at the Shakhtyor Stadium in Ekibastuz.
Question: What location hosts FC Ekibastuzets's home games? | [
"shakhtyor stadium"
] | task469-cda13794a6ea4c999b0d07cc5cdd58bc | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Chronic lymphocytic leukemia (CLL) cells depend on microenvironmental factors for proliferation and survival. In particular, the B-cell receptor (BCR) and nuclear factor- B (NF-B) pathways are activated in the lymph node (LN) microenvironment. Thus, model systems mimicking tumor-host interactions are important tools to study CLL biology and pathogenesis. We investigated whether the recently established NOD/scid/c(null) (NSG) mouse xenograft model can recapitulate the effects of the human microenvironment. We assessed, therefore, tumor characteristics previously defined in LN-resident CLL cells, including proliferation, and activation of the BCR and NF-B pathways. We found that the murine spleen (SP) microenvironment supported CLL cell proliferation and activation to a similar degree than the human LN, including induction of BCR and NF-B signaling in the xenografted cells. Next, we used this model to study ibrutinib, a Bruton's tyrosine kinase inhibitor in clinical development. Ibrutinib inhibited BCR and NF-B signaling induced by the microenvironment, decreased proliferation, induced apoptosis and reduced the tumor burden in vivo. Thus, our data demonstrate that the SP of xenografted NSG mice can, in part, recapitulate the role of the human LN for CLL cells. In addition, we show that ibrutinib effectively disrupts tumor-host interactions essential for CLL cell proliferation and survival in vivo.
Question: What is the name of Bruton's tyrosine kinase inhibitor that can be used for treatment of chronic lymphocytic leukemia? | [
"ibrutinib"
] | task469-c4ef64f7deed42bcb9d105a0c3ea483f | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Nusinersen is a 2'-O-methoxyethyl phosphorothioate-modified antisense drug being developed to treat spinal muscular atrophy. Nusinersen is specifically designed to alter splicing of SMN2 pre-mRNA and thus increase the amount of functional survival motor neuron (SMN) protein that is deficient in patients with spinal muscular atrophy. This open-label, phase 2, escalating dose clinical study assessed the safety and tolerability, pharmacokinetics, and clinical efficacy of multiple intrathecal doses of nusinersen (6 mg and 12 mg dose equivalents) in patients with infantile-onset spinal muscular atrophy. Eligible participants were of either gender aged between 3 weeks and 7 months old with onset of spinal muscular atrophy symptoms between 3 weeks and 6 months, who had SMN1 homozygous gene deletion or mutation. Safety assessments included adverse events, physical and neurological examinations, vital signs, clinical laboratory tests, cerebrospinal fluid laboratory tests, and electrocardiographs. Clinical efficacy assessments included event free survival, and change from baseline of two assessments of motor function: the motor milestones portion of the Hammersmith Infant Neurological Exam-Part 2 (HINE-2) and the Children's Hospital of Philadelphia Infant Test of Neuromuscular Disorders (CHOP-INTEND) motor function test, and compound motor action potentials. Autopsy tissue was analysed for target engagement, drug concentrations, and pharmacological activity. HINE-2, CHOP-INTEND, and compound motor action potential were compared between baseline and last visit using the Wilcoxon signed-rank test. Age at death or permanent ventilation was compared with natural history using the log-rank test. The study is registered at ClinicalTrials.gov, number NCT01839656. 20 participants were enrolled between May 3, 2013, and July 9, 2014, and assessed through to an interim analysis done on Jan 26, 2016. All participants experienced adverse events, with 77 serious adverse events reported in 16 participants, all considered by study investigators not related or unlikely related to the study drug. In the 12 mg dose group, incremental achievements of motor milestones (p<00001), improvements in CHOP-INTEND motor function scores (p=00013), and increased compound muscle action potential amplitude of the ulnar nerve (p=00103) and peroneal nerve (p<00001), compared with baseline, were observed. Median age at death or permanent ventilation was not reached and the Kaplan-Meier survival curve diverged from a published natural history case series (p=00014). Analysis of autopsy tissue from patients exposed to nusinersen showed drug uptake into motor neurons throughout the spinal cord and neurons and other cell types in the brainstem and other brain regions, exposure at therapeutic concentrations, and increased SMN2 mRNA exon 7 inclusion and SMN protein concentrations in the spinal cord. Administration of multiple intrathecal doses of nusinersen showed acceptable safety and tolerability, pharmacology consistent with its intended mechanism of action, and encouraging clinical efficacy. Results informed the design of an ongoing, sham-controlled, phase 3 clinical study of nusinersen in infantile-onset spinal muscular atrophy. Ionis Pharmaceuticals, Inc and Biogen.
Question: Which disease is treated with Nusinersen? | [
"sma",
"spinal muscular atrophy"
] | task469-ba3434abc6034a6e859533abee5f9339 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Gefitinib, the specific inhibitor of the epidermal growth factor receptor (EGFR), may cause growth delay in cancer cell lines. Thorough understanding of the downstream cellular signaling of gefitinib will facilitate the discovery of biomarkers for predicting outcomes and monitoring anti-EGFR therapies, and provide information for key targets for therapeutic intervention. In this study, we investigated the role of transducer of erbB2.1 (TOB1) in gefitinib therapy. Using the lung carcinoma cell lines A549 and NCI-H1975, the results suggested that gefitinib might mediate cell cycle arrest in lung cancer cells at least by targeting TOB1 expression. Gefitinib treatment caused cell cycle arrest predominantly at the G1 phase, which is associated with TOB1 nuclear translocation and its interaction with cyclin D1. We also showed that knockdown of TOB1 expression by RNAi rescued lung cancer cells from gefitinib-induced cell-proliferative arrest. These results suggest that TOB1 interaction with cyclin D1 and nuclear translocation is directly involved in the gefitinib-induced anti-proliferative cell cycle arrest.
Question: Which is the cellular target of gefitinib? | [
"epidermal growth factor receptor (egfr)"
] | task469-b6872e1485a741a087ab9a54db40f341 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: HD 90089 is a suspected variable star in the constellation Camelopardalis.
Question: What is the constellation that is made with HD 90089? | [
"camelopardalis"
] | task469-4a5261aa17a545668ac4d8e36994e2b1 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Private investigator Patrick Kenzie (Casey Affleck) and his partner/girlfriend Angie Gennaro (Michelle Monaghan) witness a televised plea by a woman named Helene McCready (Amy Ryan) for the return of her missing daughter Amanda, who was abducted with her favorite doll "Mirabelle". Patrick and Angie are then hired by the child's aunt Beatrice (Amy Madigan) to find Amanda and discover that Helene and her boyfriend "Skinny Ray" (Sean Malone) had recently stolen money from Cheese (Edi Gathegi), a local Haitian drug lord. After Ray is murdered, Patrick and Angie join the police detectives Remy Bressant (Ed Harris) and Nick Poole (John Ashton) with investigating the case and assist in arranging the trade of money for the return of Amanda. Captain Jack Doyle (Morgan Freeman) reads Patrick a telephone transcript of the drug lord setting up an exchange for Amanda. The exchange at a nearby quarry in Quincy is botched and it is believed Amanda drowned; her doll is found in the quarry and returned to Helene. Doyle, whose own daughter was killed years before, takes responsibility for the death and goes into early retirement. Two months later, a seven year old boy is abducted in Everett and Patrick receives information that the boy was taken by a known child molester. After entering the suspect's house and finding evidence of the abducted boy, Patrick returns with Remy and Nick to rescue him. They are seen by the residents and Nick is shot. Patrick enters the house during the shootout and finds one of the residents dead. He retreats into the child molester's room, where he finds the boy's dead body; he then shoots the child molester in the back of the head in a fit of rage. Nick later dies of his wounds. Trying to alleviate Patrick's guilt over the events at the house, Remy unthinkingly confides that he once planted evidence on someone with the help of "Skinny Ray" whom he had initially told Patrick he didn't know. After Nick's funeral, Patrick speaks to a police officer, who tells him that Remy had been asking about the drug lord's stolen money before the drug lord knew it was missing. Patrick then questions Beatrice's husband Lionel (Titus Welliver) in a bar and pieces together that Lionel and Remy had conspired to stage a fake kidnapping in order to take the drug money for themselves and to take Amanda from her neglectful mother's care. At that point, Remy (trying to cover for his earlier mistake) enters the bar, while wearing a latex mask and holding a shotgun, and stages a robbery. He points the shotgun at Lionel's head, but the bartender shoots Remy twice in the back. Remy flees and is pursued by Patrick to the rooftop of a nearby building, where he dies. Patrick is questioned by the police about Remy's death and learns that the police never had a phone transcript like the one that Doyle had read to him prior to the botched exchange. Patrick and Angie drive to Doyle's home, where Patrick finds Amanda living with Doyle and his wife; Doyle was part of the phony kidnapping all along. Patrick threatens to call the authorities, but Doyle attempts to convince him that Amanda is better off living with them than with her mother, and that is reason enough not to get involved. Patrick leaves and discusses the choices with Angie, who says she will leave him if he calls the police, since she also believes Amanda is much better off with the Doyles. In the next scene, the police arrive, Doyle is arrested, Amanda is returned to her mother amidst heavy publicity, and Patrick and Angie break up. Patrick later visits Amanda as Helene is about to leave on a date with someone she met during the publicity over her daughter's disappearance. Helene informs Patrick that Beatrice has been forbidden to visit and is upset about her husband's arrest. Helene has no babysitter for Amanda and when asked, she tells Patrick that Helene's friend, Dottie (Jill Quigg) will watch her, even though she has yet to ask Dottie herself. Patrick volunteers to watch Amanda, who is holding her
Question: What is Patrick Kenzie's profession? | [
"private investigator"
] | task469-d82ec62c08a14ea491e259f75ded577b | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Starting lineups: HOUSTON - OFFENSE: QB Matt Schaub, LT Duane Brown, LG Wade Smith, C Chris Myers, RG Mike Brisiel, RT Eric Winston, WR Andre Johnson, RB Arian Foster, FB Vonta Leach, TE Joel Dreessen, WR Kevin Walter.Hoping to snap a four-game losing streak the Texans played on home ground for an AFC South rivalry match against the Titans. The Texans took control throughout the game as QB Matt Schaub got a 1-yard TD pass to TE Joel Dreessen, followed by his 2-yard TD pass to WR Andre Johnson. The lead was increased when kicker Neil Rackers hit a 35 and a 33-yard field goal. With the easy win, the Texans improved to 5-6. However, Johnson was ejected following a fight with Titans CB Cortland Finnegan, who was also ejected.
Question: Who kicked the shortest field goal? | [
"neil rackers"
] | task469-622d1e236ea941c4b1cd6803bcc747ac | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Brink (Sir Cedric Hardwicke) has recently taken Pud's (Bobs Watson) parents in an auto wreck. Brink later comes for Gramps (Lionel Barrymore). Believing Brink to be an ordinary stranger, the crotchety old Gramps orders Mr. Brink off the property. Pud comes out of the house and asks who the stranger was. Gramps is surprised and relieved that someone else could see the stranger; he was not merely a dream or apparition. Pud tells Gramps that when he does a good deed, he will be able to make a wish. Because his apples are constantly being stolen, Gramps wishes that anyone who climbs up his apple tree will have to stay there until he permits them to climb down. Pud inadvertently tests the wish when he has trouble coming down from the tree himself, becoming free only when Gramps says he can. Pud's busybody Aunt Demetria (Eily Malyon) has designs on Pud and the money left him by his parents. Gramps spends much time fending off her efforts to adopt the boy. Brink takes Granny Nellie (Beulah Bondi) in a peaceful death just after she finishes a bit of knitting. When Mr. Brink returns again for Gramps, the old man finally realizes who his visitor is. Determined not to leave Pud to Demetria, Gramps tricks Mr. Brink into climbing the apple tree. While stuck in the tree, he cannot take Gramps or anyone else. The only way anyone or anything can die is if they touch Mr. Brink or the apple tree. Demetria plots to have Gramps committed to a psychiatric hospital when he claims that Death is trapped in his apple tree. Gramps proves his story first by proving that his doctor, Dr. Evans (Henry Travers), can not even kill a fly they have captured. He offers further proof of his power by shooting Mr. Grimes (Nat Pendleton), the orderly who has come to take him to the asylum; Grimes lives when he should have died. Dr. Evans is now a believer, but he tries to convince Gramps to let Death down so people who are suffering can find release. Gramps refuses, so the doctor arranges for the local sheriff to commit Gramps while Pud is delivered to Demetria's custody. With the help of his housekeeper (Una Merkel), Gramps tricks both of them into believing they are scheduled to go with Mr. Brink when he comes down from the tree. They beg Gramps to convince Brink otherwise, and Demetria vows never to bother Gramps or Pud again. Gramps realizes that sooner or later he will have to let Brinks downDeath is an ultimately unavoidable part of life. He tries to say goodbye to Pud, who reacts angrily and tries to run away. Mr. Brink sees Pud in the yard and dares him to climb the tree. Pud gets over the fence Gramps has had built around the tree, but falls and is crippled for life. Distraught, Gramps lets Death down from the tree. He takes both Gramps and Pud, who find they can walk again. In the final scene, they walk together up a beautiful country lane and hear Granny Nellie calling to them from beyond a brilliant light.
Question: Who does Gramps claim is trapped in his apple tree? | [
"death"
] | task469-8206107520b8424e84d688ac92148452 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Alice de Toeni, Countess of Warwick (26 April 1284 -- 1 January 1324/25) was a wealthy English heiress and the second wife of Guy de Beauchamp, 10th Earl of Warwick (1272 -- 12 August 1315), an English nobleman in the reign of Kings Edward I and Edward II. He was one of the principal opponents of Piers Gaveston, a favourite of Edward II. Alice married three times;
Question: What is Alice de Toeni, Countess of Warwick's spouse's name? | [
"guy de beauchamp, 10th earl of warwick"
] | task469-8a9c01d79a844ac1bf2eaa94f17c637f | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Madonna della seggiola or Madonna della sedia is a Madonna painting by the Italian renaissance artist Raphael, dating to c. 1513-1514 and housed in the Palazzo Pitti collection in Florence.
Question: What is the name of the place where Madonna della seggiola can be found? | [
"palazzo pitti"
] | task469-10d29b642fc24cc4b2bc89e88292da40 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: New Orleans narcotics detective Anthony Stowe (Jean-Claude Van Damme) is a heroin addict who is teetering on the edge of oblivion, and he couldn't care less.At the moment, Stowe is trying to bring down his former partner Gabriel Callahan (Stephen Rea), who has become a drug kingpin. Callahan is trying to, and slowly succeeding at, taking over the New Orleans underworld.Stowe botches a sting operation against Callahan, resulting in the death of fellow cop Maria Ronson (Rachel Grant), whose fiancee, fellow cop Van Huffel (Adam Leese), is furious at Stowe. Chief Mac Baylor (Gary Beadle) has a very blunt chat with Stowe about it. Stowe is approached by fellow cop Walter Curry (Trevor Cooper) to help his nephew beat a drug-dealing charge. Stowe instead turns him over to Baylor, who fires him. After barricading himself in the station bathroom, Walter confronts an unrepentant Stowe and condemns him for betraying his fellow officers.Later, Van Huffel berates Stowe for getting Maria killed. Stowe responds by attacking Van Huffel in front of several officers. Later, Stowe meets with his estranged wife Valerie (Selina Giles), who tells him that she's pregnant, but that he's not the father. Valerie, whose marriage with Stowe is on the rocks, has been seeing a man named Mark Rossini (Mark Dymond), the gym teacher at the school she is principle of. But he may not be the father either. Stowe brashly accuses Valerie of being impregnated by Callahan, and Valerie tells him she never wants to see him again.The only thing keeping Stowe from total collapse is his dogged pursuit of Callahan. But he drunkenly stumbles into an ambush masterminded by Callahan, and is shot in the head by Callahan's right-hand man Jimmy (Stephen Lord).Stowe undergoes emergency surgery, and ends up in a coma. Months later, he recovers to the point that he opens his eyes, and is transported to his and Valerie's house to recover properly.Seven months after getting shot, Stowe has recovered a lot, although he must learn to walk and speak again. He manages to survive an attempt on his life, by someone who appears to be a cop. He's recovered enough to try to get his job back, but that's the one thing that Chief Baylor doesn't want to give him. The coma has led to his decision to become a better man, and to right some wrongs. He reconciles with his wife, although awkwardly, and gives Walter a check for $40,000, part of his insurance money that compensated his time in a coma. Finally, he visits the grave of fellow police officer Serge (William Ash), who once saved Stowe's life but has been killed by an unknown attacker following another failed sting operation.Valerie packs up to move out of the house so she can live with Mark, but after realizing the change that Stowe has undergone, she later decides to leave Mark and come back home. Stowe is convinced by his friend Chad Mansen (Wes Robinson) not to let his wife go, and Stowe goes after her. They miss each other by a few minutes.Just after Valerie returns and meets Chad, some of Callahan's men show up. Jimmy kills Chad, and kidnaps Valerie. Stowe returns to the house, and finds Chad's body, along with Jimmy waiting for him.Van Damme promoting the film in 2007Jimmy takes Stowe to a warehouse where Callahan is waiting. Along the way, Stowe manages to overpower Jimmy and take his gun, but he finds that the odds against him are impossible- and Callahan has Valerie hostage. Van Huffel is revealed to be Callahan's mole on the police force, and the sting operation at the beginning of the film was a set-up. Walter suddenly arrives and saves Stowe. Together they kill all of Callahan's men, including Jimmy and Van Huffel, as Callahan tries to escape with Valerie to his helicopter. Just as Callahan is about to reach it, Stowe appears.In the European DVD ending, each fire a shot that kills the other. Valerie cries out
Question: What happened at the helicopter? | [
"stowe appears"
] | task469-cbbe34346a364c8c988ba4a4eb8e6b26 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Godfather Part II presents two parallel storylines. One involves Mafia chief Michael Corleone in 1958/1959 after the events of the first movie; the other is a series of flashbacks following his father, Vito Corleone from 1917 to 1925, from his youth in Sicily (1901) to the founding of the Corleone family in New York.The film begins in 1901, in the town of Corleone, Sicily, at the funeral of young Vito's father, Antonio Andolini, who has been murdered for an insult to the local Mafia lord, Don Ciccio. During the procession, Vito's older brother is murdered because he swore revenge on the Don. Vito's mother goes to Ciccio to beg for mercy, but he refuses, knowing that nine-year-old Vito will seek revenge later in life. The mother takes Ciccio hostage at knifepoint, allowing her son to escape, and Ciccio's men kill her. They search the town for the boy, but he is aided in his escape by the townspeople. Vito finds his way by ship to New York, and at Ellis Island an immigration agent chooses Vito's hometown of Corleone as his surname, and he is registered as "Vito Corleone".In 1958 in a scene similar to the opening of the first film, Michael Corleone (Al Pacino), Godfather of the Corleone family, deals with various business and family problems during an elaborate party at his Lake Tahoe, Nevada compound to celebrate his son's First Communion. In his office, Michael meets with corrupt Nevada Senator Pat Geary (G. D. Spradlin) to discuss the price of the gaming licenses for the hotel/casinos the Family is buying. Geary, who has obvious contempt for Michael and other Italian businessmen who are moving into his state to take advantage of gambling opportunities, promises to make Michael's acquisition of his gaming license a difficult process. Michael ends his conversation with Geary when he refuses to pay the outrageous fee Geary demands, telling the senator he'll get nothing.Michael also deals with his self-indulgent younger sister Connie (Talia Shire), who, although recently divorced from her second husband, is planning to marry a man named Merl Johnson (Troy Donahue) with no obvious means of support and of whom Michael disapproves. He also talks with Johnny Ola (Dominic Chianese), the right hand man of Jewish gangster Hyman Roth (Lee Strasberg), who is supporting Michael's move into the gambling industry. Belatedly, Michael deals with Frank "Five Angels" Pentangeli (Michael V. Gazzo), a business associate who took over Corleone caporegime Peter Clemenza's territory in New York City after his death, and now has problems with the Rosato Brothers, who are backed by Roth. Pentangeli leaves abruptly, after telling Michael "your father did business with Hyman Roth, your father respected Hyman Roth, but your father never trusted Hyman Roth."Later that night, Michael barely escapes an assassination attempt when his wife Kay (Diane Keaton) notices the bedroom window drapes are inexplicably open, which allows two unseen hitmen to spray the bedroom with bullets. The two hitman are found dead having been killed by a "mole" within the compound. Afterwards, Michael tells his lawyer and associate Tom Hagen (Robert Duvall) that the hit was made with the help of someone close, and that he must leave, entrusting all his power to Hagen to protect his family.Flashback: In 1917 New York City, the adult Vito Corleone (Robert De Niro) works in a grocery store in the Lower East side with his friend Genco Abbandando. The neighborhood is controlled by a member of the "The Black Hand," Don Fanucci (Gastone Moschin), who extorts protection payments from local businesses. One night, Vito's neighbor Clemenza (Bruno Kirby) asks him to hide a stash of guns for him, and later, to repay the favor, takes him to a fancy apartment where they commit their first felony together, stealing an elegant rug.The film flash-forwards to Michael's time. Michael meets with poushal Hyman Roth in Miami, Florida who tells Michael that he believes Frank Pentangeli was responsible for the assassination attempt, and that Pentangeli will pay for it
Question: Whose criminal conduct attracts the attention of Fanucci? | [
"vito's"
] | task469-b8f4b4b55c8946b6871d5b8275a683e6 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Ant & Dec are an English comedy TV presenting duo, consisting of Anthony McPartlin OBE and Declan Donnelly OBE , from Newcastle upon Tyne, England. Formed after their meeting as actors on CBBC's drama, Byker Grove, the duo have led successful careers as television presenters, with hosting credits including SMTV Live, CD:UK, Friends Like These, Pop Idol, Ant & Dec's Saturday Night Takeaway, I'm a Celebrity...Get Me Out of Here!, PokerFace, Push the Button, Britain's Got Talent, Red or Black?, and Text Santa. Due to a difference in height - Ant being the taller at 5ft 8in , and Dec being two inches shorter at 5ft 6in - the pair identify themselves in the media by adopting the use of the 180-degree rule, with the exception of some early publicity shots. In addition to presenting, the duo are accomplished actors - both had leading roles in the 2006 film Alien Autopsy - operate as television producers - they own their own production company, Mitre Television - have presented the annual Brit Awards in 2001, 2015 and 2016, and are former pop musicians who operated under the aliases of their characters from Byker Grove. In a 2004 poll for the BBC, Ant & Dec were named the eighteenth most influential people in British culture.
Question: On which show did Anthony and Declan meet? | [
"byker grove"
] | task469-accd40a518514b2686b59c2050e4515d | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: As the movie opens, we see a guy climbing along the underside of an outcropping from a tall mountain peak. He turns out to be Gabe Walker, a ranger with Rocky Mountain Rescue. (Yes, that makes him "Ranger Walker," and he is addressed as such several times during the course of the movie.) He is in communication with his co-worker and girlfriend, Jessie, who is on a chopper piloted by an older co-worker, Frank. The three are mounting a rescue of yet another co-worker, Hal Tucker, and his girlfriend Sarah, who is on her first climb. Hal and Sarah made it to the top of the mountain, but Hal has aggravated an old knee injury and can't make it back down.Gabe makes it to the top of the peak where Hal and Sarah are. The chopper drops Gabe a cable, which he secures, while the chopper lands on a nearby peak. All is set for the three to shuttle across the cable to where the chopper is. There is a lot of light-hearted banter as this is a routine operation that they all (except Sarah) do all the time. Hal goes first, and as he is crossing, Gabe asks Sarah how Hal persuaded her to accompany him on this escapade. She replies laconically, "He told me it's better than sex."Hal makes it across and now it's Sarah's turn. She is a little frightened at the thought of hanging from a cable 4,000 feet above the ground, but the fact that Hal crossed without incident is reassuring. Halfway across her equipment fails and suddenly she is hanging by a strap and unable to reach and grab onto the cable. Gabe quickly crosses to her and grabs her arm just as the strap breaks free. But they are unable to keep their grip on each other, and Sarah falls 4,000 feet to her death. This is by far the most dramatic and gripping scene in the movie and some viewers will be haunted by it for weeks afterwards. But really, except for providing some background for the interpersonal dynamics among the remaining characters, it has nothing to do with the plot of the rest of the movie.Fast forward eight months, and we pick up two different plot lines that will converge later. At the U.S. Treasury office in Denver, Treasury Agent Travers is preparing to leave on a flight with several large containers of printed currency totaling $100,000,000. His boss introduces FBI Agent Matheson, who is being transferred and is bumming a ride on the flight. Gabe, meanwhile, drives up to Jessie's (and formerly his) house. He had left after Sarah's funeral because he felt he had to get away, and has been working in Denver. He wants Jessie to come to Denver with him, but she won't. She leaves for work, leaving Gabe to get his stuff from the house and load it into his vehicle.On the plane, Matheson looks out his window and sees another plane flying next to them. He quickly and correctly sizes up the situation, informs the other two Treasury agents that Travers intends to hijack the plane, and pulls his gun on Travers. The other two agents dutifully pull their guns on Matheson, as does Travers. Travers shoots the other two agents, then shoots Matheson. In the cockpit, the co-pilot comments about the gunfire, and the pilot shoots him. The two planes move into position and run a cable between them. Travers transfers over, then the pilot sends the containers.But Matheson isn't dead. He manages to shoot the pilot, shoot the cable in enough places that it detaches from both planes and the containers fall to the ground, and shoot the other plane enough times that it crashes in the mountains, before his own plane explodes from explosives previously set by Travers. Kristel, the pilot of the other plane, radios for help, reaches Jessie, Hal, and Frank, tells them they are hikers who got lost in a snowstorm, and asks them to send a chopper. But they can't send a chopper because of the storm, so Hal sets off to
Question: Who is Frank? | [
"older co-worker"
] | task469-e8ee797af39f49fd961de295501bf658 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: In the county, the population was spread out with 23.5% under the age of 18, 7.8% from 18 to 24, 28.5% from 25 to 44, 25.9% from 45 to 64, and 14.2% who were 65 years of age or older. The median age was 40 years. For every 100 females, there were 93.8 males. For every 100 females age 18 and over, there were 90.5 males.
Question: Which age group had the fourth most people? | [
"65 years of age"
] | task469-4768fcc0d74b4992994e7b47db55e255 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The film opens where the previous film ended, set a few years later, where Rafiki (Robert Guillaume) gathers the animals of the Pride Lands together for the presentation of Simba (Matthew Broderick) and Nalas (Moira Kelly) new daughter Kiara. Mufasa's spirit (James Earl Jones) watches over the ceremony. Later, Simba becomes very overprotective of an older Kiara (Michelle Horn), assigning Timon and Pumbaa (Nathan Lane and Ernie Sabella) to watch her. One day as Kiara was playing, she fell into a small pond as Timon and Pumbba got her back onto land. Kiara tells them only half of her is a princess. Pumbba asks, "Well, who's the other half?" While they wait for her to answer, they start having a snack. Then they started arguing about slimy and crunchy grubs. While they were arguing, Kiara sneaks into the "Outlands" where she meets a young cub named Kovu (Ryan O'Donohue). After escaping a river filled with nile crocodiles, the two become friendly, unaware they are being watched by Kovu's mother, Zira (Suzanne Pleshette). Simba arrives and confronts Zira, who reminds Simba that he exiled the Outsiders, and that if he wants to punish them, Kovu is Scar's hand-chosen successor. Unwilling to harm the cub, Simba orders them to leave. Later Simba scolds Kiara for endangering herself. In the Outlands, Zira's eldest son, Nuka (Andy Dick), complains to his younger sister Vitani (Lacey Chabert) about Kovu's status as "the Chosen One" the cub chosen by Scar to lead the pride after his death. ("I should've been the "Chosen One". I'm the strongest, I'm the smartest, I'm the oldest, etc.") At that moment, Zira returns and scolds both of her sons, but Kovu accidentally gives her the idea to use Kovu's new friendship with Kiara as a means of exacting her revenge on Simba for Scar's death. Now an adult, Kiara (Neve Campbell) heads out from home for her first solo hunt, however Simba again sends Timon and Pumbaa to follow and watch her progress after he promised to let Kiara hunt on her own. Furious to find out her father still insists on maintaining surveillance, Kiara goes further from home to hunt, though is still unsuccessful in her efforts. Meanwhile, Zira's plan to implant Kovu in Simba's pride has been set in motion; Nuka and Vitani (Jennifer Lien) set fire to the plains where Kiara is hunting, causing her to faint and giving Kovu (Jason Marsden) the chance to rescue her. Drawn by the smoke, Simba finds them together and reluctantly accepts Kovu's request to come to Pride Rock in return for saving Kiara's life, though he forces Kovu to sleep outside. That same night, Simba has a nightmare about his father's death, where Scar suddenly morphs into Kovu and Simba takes his father's place falling off the cliff. The next morning, he goes outside to a watering hole where Kovu contemplates attacking him, but Kiara interrupts and they go off together so Kovu can help her learn how to hunt. Kiara kept on failing. During the lesson, Kovu was setting an example for Kiara, thinking Timon was just an ordinary meerkat. They run into Timon and Pumbaa struggling with some birds, so the two lions help them chase the birds off. Together, they have fun playing, something Kovu notes he has never experienced before. That night, Kovu tells Kiara that he is not Scar's real son, but "was a part of him". Simba watches from above, seeking guidance from the "Great Kings" and Nala advises him to give Kovu a chance, because he is not his father. Kovu decides to leave after he almost confesses his real intentions to Kiara, but Rafiki stops him and invites the young lions to experience "Upendi" love. After a musical journey through the jungle, the two fall in love. In the morning, Simba invites Kovu for a walk and tells him the true story of
Question: Who is Simba and Nala's firstborn offspring? | [
"kiara"
] | task469-ade1af0cd2e24cd884a0b1272ee1d30f | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Ehlers-Danlos syndromes (EDS) are a heterogeneous group of heritable connective tissue disorders characterised by joint hypermobility, involvement of skin and tissue fragility. The Villefranche criteria have simplified its diagnosis, which, however, remains difficult in children and young adults with vascular and hypermobile EDS as well as in patients without a positive family history. Diagnosis of vascular EDS is important for clinical follow-up, genetic counseling and prenatal diagnosis. We describe the biochemical and molecular-genetic diagnosis of vascular EDS. We describe five families with vascular EDS. Analysis of (pro)collagens obtained from cultured fibroblasts was done using SDS-PAGE. The structure and amounts of (pro)collagen I, III and V were determined by autoradioflourography. This was also done in 362 controls or patients without a diagnosis of vascular EDS. Molecular testing was done in Professor Anne de Paepe's laboratory in Belgium by sequencing of COL3A1. (Pro)collagen from all five patients with vascular EDS was abnormal by SDS-PAGE: intracellular retention, reduced secretion and overmodification of the a1 chains of (pro)collagen III. Molecular analysis revealed an abnormality of COL3A1 in all patients. Abnormalities of (pro)collagen III were not observed in patients without a diagnosis of vascular EDS. Among 90 patients with non-vascular EDS, one patient had an abnormality of collagen I. Biochemical analysis of (pro)collagen obtained from cultured fibroblasts is a good screening procedure for vascular EDS, but it is of limited value in non-vascular EDS. Molecular testing will disclose an abnormality of COL3A1 in many patients with abnormal (pro)collagen III on SDS-PAGE. The findings make precise genetic counselling and prenatal diagnosis possible in families with vascular EDS.
Question: What tissue is most affected in Ehlers-Danlos syndromes? | [
"connective tissue"
] | task469-f7304d5263714ac1975d580a3de48dde | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Ptolemy III Euergetes (Greek: , Ptolemaios Euergetes, reigned 246--222 BC) was the third king of the Ptolemaic dynasty in Egypt.
Question: What family lineage was Ptolemy III Euergetes part of? | [
"ptolemaic dynasty"
] | task469-52370dd55e4a4f8abf9f1ff8b59ff831 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Linth (pronounced (lnt) ''lint'') is a Swiss river that rises near the village of Linthal in the mountains of the canton of Glarus, and eventually flows into the Obersee section of Lake Zurich.
Question: What river does Linth turn into? | [
"lake zurich"
] | task469-4c7bf748aaf640be8ba4a86c47672d19 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Your bodys first line of defense is like a castles moat and walls. It keeps most pathogens out of your body. The first line of defense includes physical, chemical, and biological barriers. The skin is a very important barrier to pathogens. It is the bodys largest organ and the most important defense against disease. It forms a physical barrier between the body and the outside environment. The outer layer of the skin, called the epidermis, consists of dead cells filled with the protein keratin. These cells form a tough, waterproof covering on the body. It is very difficult for pathogens to get through the epidermis. The inside of the mouth and nose are lined with mucous membranes. Other organs that are exposed to substances from the environment are also lined with mucous membranes. These include the respiratory and digestive organs. Mucous membranes arent tough like skin, but they have other ways of keeping out pathogens. One way mucous membranes protect the body is by producing mucus. Mucus is a sticky, moist secretion that covers mucous membranes. The mucus traps pathogens and particles so they cant enter the body. Many mucous membranes are also covered with cilia. These are tiny, hair-like projections. Cilia move in waves and sweep mucus and trapped pathogens toward body openings. You can see this in the diagram in Figure 21.10. When you clear your throat or blow your nose, you remove mucus and pathogens from your body. In addition to mucus, your body releases a variety of fluids, including tears, saliva, and sweat. These fluids contain enzymes called lysozymes. Lysozymes break down the cell walls of bacteria and kill them. Your stomach contains a very strong acid, called hydrochloric acid. This acid kills most pathogens that enter the stomach in food or water. Urine is also acidic, so few pathogens are able to grow in it. Your skin is covered by millions of bacteria. Millions more live inside your body, mainly in your gastrointestinal tract. Most of these bacteria are helpful. For one thing, they help defend your body from pathogens. They do it by competing with harmful bacteria for food and space. They prevent the harmful bacteria from multiplying and making you sick. Did you ever get a splinter in your skin, like the one in Figure 21.11? It doesnt look like a serious injury, but even a tiny break in the skin may let pathogens enter the body. If bacteria enter through the break, for example, they could cause an infection. These bacteria would then face the bodys second line of defense. If bacteria enter the skin through a splinter or other wound, the area may become red, warm, and painful. These are signs of inflammation. Inflammation is one way the body reacts to infections or injuries. It occurs due to chemicals that are released when tissue is damaged. The chemicals cause nearby blood vessels to dilate, increasing blood flow to the area. The chemicals also attract white blood cells to the area. The white blood cells leak out of the blood vessels and into the damaged tissue. You can see an animation of the inflammatory response by watching this video: MEDIA Click image to the left or use the URL below. URL: The white blood cells that go to a site of inflammation and leak into damaged tissue are called phagocytes. They start eating pathogens and dead cells by engulfing and destroying them. This process is called phagocytosis. You can see how it happens in Figure ??. You can see it in action in the animation at this link: [Link] Phagocytes also release chemicals that cause a fever. A fever is a higher-than-normal body temperature. Normal human body temperature is 98.6 F (37 C). Most bacteria and viruses that infect people reproduce quickly at this temperature. When the temperature rises higher, the pathogens cant reproduce as quickly. Therefore, a fever helps to limit the infection. A fever also causes the immune system to make more white blood cells to fight the infection.
Question: __tiny, hair-like projections that cover many mucous membranes | [
"cilia"
] | task469-991dc2af2a124ce3806c2864218c550d | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Following their victory over the Patriots, the Steelers remained at home the next week for their second match-up of the season against division rivals the Baltimore Ravens. The Ravens scored first with an 18-yard field goal by kicker Billy Cundiff, the only points scored in the first quarter by either team. Steelers kicker Shaun Suisham answered with a 36-yard field goal early in the second quarter, and a 30-yard field goal near the end, but both of these were quickly matched by Baltimore's Cundiff with a 43-yard and 51-yard field goal, respectively, giving Baltimore a 9-6 lead at halftime. The Ravens then increased their lead in the third quarter when Ray Rice scored the first touchdown of the game on a 4-yard run. The Steelers rallied hard in the fourth quarter, with running back Rashard Mendenhall making a 1-yard run to score a touchdown, and then taking the lead for the first time in the game when quarterback Ben Roethlisberger made a successful 25-yard pass to wide receiver Mike Wallace in the endzone for a second touchdown. On their final drive of the game, the Steelers were ready to potentially increase their lead with a 47-yard field goal kick by Shaun Suisham, but a 5-yard delay of game penalty put them out of field goal range and they were instead forced to punt the ball to the Ravens. The Ravens then began a 92-yard drive, culminating in a 26-yard touchdown pass by quarterback Joe Flacco to wide receiver Torrey Smith in the endzone with just 8 seconds remaining, giving them the game.
Question: Who kicked the two longest field goals of the game? | [
"billy cundiff"
] | task469-981ba9b06eaa403ebbe7262602af5dee | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: A solenoid is a coil of wire with electric current flowing through it, giving it a magnetic field (see Figure 25.5). Recall that current flowing through a straight wire produces a weak electromagnetic field that circles around the wire. Current flowing through a coil of wire, in contrast, produces a magnetic field that has north and south poles like a bar magnet. The magnetic field around a coiled wire is also stronger than the magnetic field around a straight wire because each turn of the wire has its own magnetic field. Adding more turns increases the strength of the field, as does increasing the amount of current flowing through the coil. You can see an actual solenoid with a compass showing its magnetic north pole at this URL: . Solenoids are the basis of electromagnets. An electromagnet is a solenoid wrapped around a bar of iron or other ferromagnetic material (see Figure 25.6). The electromagnetic field of the solenoid magnetizes the iron bar by aligning its magnetic domains. The combined magnetic force of the magnetized iron bar and the wire coil makes an electromagnet very strong. In fact, electromagnets are the strongest magnets made. Some of them are strong enough to lift a train. The maglev train described earlier, in the lesson "Electricity and Magnetism," contains permanent magnets. Strong electromagnets in the track repel the train magnets, causing the train to levitate above the track. Like a solenoid, an electromagnet is stronger if there are more turns in the coil or more current is flowing through it. A bigger bar or one made of material that is easier to magnetize also increases an electromagnets strength. You can see how to make a simple electromagnet at this URL: (4:57). MEDIA Click image to the left or use the URL below. URL: Many common electric devices contain electromagnets. Some examples include hair dryers, fans, CD players, telephones, and doorbells. Most electric devices that have moving parts contain electric motors. You can read below how doorbells and electric motors use electromagnets. Figure 25.7 shows a diagram of a simple doorbell. Like most doorbells, it has a button located by the front door. Pressing the button causes two electric contacts to come together and complete an electric circuit. In other words, the button is a switch. The circuit is also connected to a voltage source, an electromagnet, and the clapper of a bell. When current flows through the circuit, the electromagnet turns on, and its magnetic field attracts the clapper. This causes the clapper to hit the bell, making it ring. Because the clapper is part of the circuit, when it moves to strike the bell, it breaks the circuit. Without current flowing through the circuit, the electromagnet turns off. The clapper returns to its original position, which closes the circuit again and turns the electromagnet back on. The electromagnet again attracts the clapper, which hits the bell once more. This sequence of events keeps repeating as long as the button by the front door is being pressed. An electric motor is a device that uses an electromagnet to change electrical energy to kinetic energy. Figure 25.8 shows a simple diagram of an electric motor. The motor contains an electromagnet that is connected to a shaft. When current flows through the motor, the electromagnet turns, causing the shaft to turn as well. The rotating shaft moves other parts of the device. Why does the motors electromagnet turn? Notice that the electromagnet is located between the north and south poles of two permanent magnets. When current flows through the electromagnet, it becomes magnetized, and its poles are repelled by the like poles of the permanent magnets. This causes the electromagnet to turn toward the unlike poles of the permanent magnets. A device called a commutator then changes the direction of the current so the poles of the electromagnet are reversed. The reversed poles are once again repelled by the like poles of the permanent magnets. This causes the electromagnet to continue to turn. These events keep repeating, so the electromagnet rotates continuously. You can make a very simple electric motor with a battery, wire, and magnet following instructions at this URL: .
Question: part of an electric motor that changes the direction of the current | [
"commutator"
] | task469-337d68c8b8eb47898b8ef215984a20a2 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: September 1939. Mrs. Kay Miniver (Greer Garson) and her family live a comfortable life at a house called 'Starlings' in Belham, a fictional village outside London, England. The house has a large garden, with a private landing stage on the River Thames at which is moored a motorboat belonging to her devoted husband Clem (Walter Pidgeon), a successful architect. They have three children: the youngsters Toby and Judy (Christopher Severn and Clare Sandars) and an older son Vin (Richard Ney) at university. They have live-in staff: Gladys the housemaid (Brenda Forbes) and Ada the cook (Marie De Becker).As World War II looms, Vin comes down from university and meets Carol Beldon (Teresa Wright), granddaughter of Lady Beldon (Dame May Whitty) from nearby Beldon Hall. Despite initial disagreements (mainly contrasting Vin's idealistic attitude to class differences with Carol's practical altruism) they fall in love. Vin proposes to Carol in front of his family at home after his younger brother prods him to give a less romantic but more honest proposal.Several months later, as the war comes closer to home with the bombing of Great Brittan, Vin feels he must "do his bit" and enlists in the Royal Air Force, qualifying as a fighter pilot. He is posted to a base near to his parents' home and is able to signal his safe return from operations to his parents by cutting his engines briefly as he flies over the house. Together with other boat owners, Clem volunteers to take his motorboat to assist in the May-June 1940 Dunkirk evacuation.Early one morning, Kay unable to sleep as Clem is still away, wanders down to the landing stage. She is startled to discover a wounded German pilot (Helmut Dantine) hiding in her garden and he holds her at gunpoint. Demanding food and a coat, the pilot maniacally asserts that the Third Reich will mercilessly overcome its enemies. She feeds him, calmly disarms him and then calls the police. Soon after, Clem returns home, exhausted, from Dunkirk.Lady Beldon visits Kay to try and convince her to talk Vin out of marrying Carol on account of her granddaughter's comparative youth. Lady Beldon is unsuccessful and admits defeat when Kay reminds her that she, too, was young when she married her late husband. Lady Beldon concedes defeat and realises that she would be foolish to try and stop the marriage. Vin and Carol are married; Carol has now also become Mrs Miniver, and they return from their honeymoon in Scotland. A key theme is that she knows he is likely to be killed in action, but the short love will fill her life. Later, Kay and her family take refuge in their Anderson shelter in the garden during an air raid, and attempt to keep their minds off the frightening bombing by reading Alice's Adventures in Wonderland, which Clem refers to as a "lovely story" as they barely survive a bomb destroys parts of the house. They take the damage with nonchalance.At the annual village flower show, Lady Beldon silently disregards the judges' decision that her rose is the winner, instead announcing the entry of the local stationmaster, Mr. Ballard (Henry Travers), named the "Mrs. Miniver" rose, as the winner, with her own rose taking second prize. As air raid sirens sound and the villagers take refuge in the cellars of Beldon Hall, Kay and Carol drive Vin to join his squadron. On their journey home they witness fighter planes in a 'dogfight'. For safety, Kay stops the car and they see the German plane crash. Kay realises Carol has been wounded by shots from the plane and takes her back to 'Starlings'. She dies a few minutes after they reach home. Kay is devastated. When Vin returns from battle, he already knows the terrible news. Unexpectedly he is the survivor, and she the one who gives her life for England.The villagers assemble at the badly damaged church where their vicar (Henry Wilcoxon) affirms their determination in a powerful sermon:"We in this quiet corner of England have suffered the loss of friends very dear to us, some
Question: Who did the judges say won the flower show? | [
"lady beldon."
] | task469-4a74d870290745f48b56937b5669433f | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Coming off their bye week, the Jets stayed at home for a Week 10 duel with the Jacksonville Jaguars. New York would trail early in the first quarter with running back Maurice Jones-Drew's 33-yard touchdown run. The Jets would respond with kicker Jay Feely getting a 32-yard field goal, followed by rookie quarterback Mark Sanchez completing a 7-yard touchdown pass to wide receiver Jerricho Cotchery. In the second quarter, Jacksonville would take the lead as quarterback David Garrard got an 11-yard touchdown run and completed a 26-yard touchdown pass to wide receiver Mike Sims-Walker. New York would close out the half as Feely made a 37-yard field goal. After a scoreless third quarter, the Jets would regain the lead in the fourth quarter with a 40-yard field goal from Feely and a 1-yard touchdown run from running back Thomas Jones (with a failed 2-point conversion). However, the Jaguars got the last laugh as kicker Josh Scobee booted the game-winning 21-yard field goal.
Question: Who kicked the third longest field goal? | [
"feely"
] | task469-dd94107e76ab4cb09ddd398143e8599d | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: An English teacher named Seiji Hasumi (Hideaki Ito) is loved by his students and respected by his peers. He graduates from Harvard University with an MBA, and works at Morgenstern, a European investment bank, for two years. Hasumi returns to Japan to pursue high school teaching. However, his outward charm masks his true nature. In reality, Hasumi is a sociopath who is unable to feel empathy for other human beings. Specifically, he has a severe antisocial personality disorder. Having killed both of his parents and his former tutor at the age of fourteen, Hasumi turns into a fiendishly clever killer. During his time in the States, Hasumi meets a partner in crime, an American named Dave, who thinks he shares the same "hobby" as Hasumi killing people for fun. The two can be seen carrying buckets full of human blood, bones, and organs somewhere, giving off the notion that they committed numerous murders while working together. Hasumi eventually kills his partner by knocking him out and burning him alive inside a barrel, stating that while Dave enjoys killing for fun, Hasumi does not. Back in Japan, Hasumi chooses to deal with problems like bullying and student sexual harassment, starting by dealing with the school cheating issue. Upon collecting all of the students' cell phones prior to their exams, Hasumi secretly uses a cell phone jammer to completely prevent any cheating during the test. The group of students that had cheated on previous exams became suspicious after none of the group's cell phones have service during the test and immediately suspect the adviser of the Radio Club, Tsurii - a loner Physics teacher. They are then confronted by Tsurii himself who clarifies that he was not responsible for the jamming. A man who regularly meets with the school to complain about students bullying his daughter, Rina, is murdered. Someone has replaced the bottles of water he kept around his house to scare off cats with kerosene, as the man is a chainsmoker the bottles soon catch fire and explode. Tsurii soon meets with the intelligent ringleader of the cheating group, Keisuke, revealing his suspicions of Hasumi. Tsurii explains he has dug into Hasumi's past and found strange details, such as at another school where Hasumi started his teaching career that later had four student suicides. During this time, however, Hasumi had bugged the room and learned of Tsurii's suspicion, and confronts him on a train, murdering him and making his death appear as a hanging suicide. Hasumi then confronts Keisuke after the announcement of Tsurii's suicide causes him to panic. Hasumi knocks Keisuke out and ties him up until the end of school, after which Hasumi tortures him into admitting that he and his friends were indeed cheating. Hasumi checks that Keisuke didn't tell others of Tsurii's suspicions, before killing him and hiding his body. During the same time period, Hasumi is brought to the attention of a blackmail case from one of his students. A store owner, Meka, caught a female student, Miya, shoplifting but swears not to charge her for it. However, PE teacher Shibahara blackmails Miya, as he has recorded her admission of shoplifting, into giving him sexual favors or risk being charged. Hasumi, assures Miya that a blackmail and statutory rape case is more serious than shoplifting and affirms to her that she is safe from the law and no longer needs to succumb to the blackmail. Miya later meets Hasumi on the school roof, she thanks him with a hug that advances into a kiss and the two become lovers. In the meantime, Hasumi finds out about art teacher Kume's sexual relationship with a male student; he blackmails Kume into lending him his luxury apartment. Hasumi later takes Miya to the apartment and the two have sex. Hasumi presses Miya into giving him access to an online private discussion board that his students use, anonymously making claims about the murder of Rina's father, accusing delinquent student Tadenuma, who had targeted Rina online previously. After a fight breaks out at the school, Hasumi invites Tadenuma out for a drink and murders him; the students later assume that Tadenuma ran away from home. Events have passed until Hasumi's homeroom students are
Question: Who is the advisor of the radio club? | [
"tsurii"
] | task469-4831c8e0b2a24069b673c33430e88e93 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: One Shell Square is a 51-story, 697-foot (212 m) skyscraper designed in the International style by Skidmore, Owings and Merrill, located at 701 Poydras Street in the Central Business District of New Orleans, Louisiana.
Question: The designer for One Shell Square was? | [
"skidmore, owings and merrill"
] | task469-7a6ebbb1b6b54f4f96595921d3befd8a | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Chronic myeloid leukemia (CML) is a progressive and often fatal myeloproliferative disorder. The hallmark of CML is an acquired chromosomal translocation known as the Philadelphia chromosome (Ph) that results in the synthesis of the BCR-ABL fusion protein, a constitutively active tyrosine kinase (TK). The introduction of imatinib, a TK inhibitor (TKI) specific for BCR-ABL, was a major breakthrough in CML therapy. Although most patients respond to first-line imatinib therapy, some experience a loss of response (resistance) or require treatment discontinuation because of toxicity (intolerance). In patients for whom standard-dose imatinib therapy (400 mg/day) fails, imatinib dose escalation (600-800 mg/day) is a second-line option. However, high-dose imatinib is not an appropriate approach for patients experiencing drug toxicity, and there remain questions over the durability of responses achieved with this strategy. Alternative second-line options include the newer TKIs dasatinib and nilotinib. A substantial amount of long-term data for these agents is available. Although both are potent and specific BCR-ABL TKIs, dasatinib and nilotinib exhibit unique pharmacologic profiles and response patterns relative to different patient characteristics, such as disease stage and BCR-ABL mutational status. To optimize therapeutic benefit, clinicians should select treatment based on each patient's historical response, adverse event tolerance level, and risk factors.
Question: What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)? | [
"bcr-abl"
] | task469-c412f8c9e78345ba969109c45e7089ba | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: As Tsushima had suffered greatly from its loss of trade with Korea as a result of the invasions, Yoshitoshi of the So family, then dominant in Tsushima, undertook the lead in the peace negotiations by Japan. He sent four peace missions to Joseon in 1599 to normalize relations. The first three were captured and sent directly to Beijing by Chinese troops, but the fourth one, in 1601, successfully obtained from the Joseon court the promise of a normalizing of relations upon the return of remaining Joseon captives. As Ming troops continued to be present in Korea following the withdrawal of Japanese forces, the major incentive for Joseon for the normalization of relations with Japan was the withdrawal of the Chinese soldiers from their territory. The Ming Chinese themselves were causing as much havoc as the Japanese had during the actual conflict, and their presence continued to strain Joseon's national economy and infrastructure. In response to the Joseon request, Yoshitoshi promptly released several Joseon prisoners and between 1603 and 1604 helped the Joseon envoys to repatriate a further 3,000 by organizing negotiations at Kyoto with Tokugawa Ieyasu, by then the Shogun of Japan. In the continuation of the diplomatic talks toward peaceful relations, Joseon in 1606 expanded its conditions and demanded that the Shogun write a formal letter requesting peace, and to extradite the Japanese soldiers who had defiled the Joseon Royal Tombs near Hanseong . Realizing that the Shogunate would never agree to such a request, Yoshitoshi sent a forged letter and a group of criminals instead; the great need to expel the Ming soldiers pushed Joseon into accepting and to send an emissary in 1608. The end result was a return of Joseon prisoners and the restoration of diplomatic and trade relations between the two countries.
Question: Who sent four peace missions to Joseon in 1599? | [
"yoshitoshi of the sō family"
] | task469-cbcaf43bc91f4d30862261943d834abc | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Westerhout 43, also known as W43, is a region of star formation of our galaxy located in the constellation of Aquila at a distance of 6 kilo-parsecs (nearly 20,000 light-years) of the Sun, that is considered the region of the Milky Way that is most actively forming stars.
Question: Of which constellation is Westerhout 43 a part? | [
"aquila"
] | task469-9f7f368b3d2a4a0ca9250ed978e39f69 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Giant Mine was a large gold mine located on the Ingraham Trail just outside Yellowknife, Northwest Territories.
Question: What is the product made by Giant Mine? | [
"gold"
] | task469-afabf4c221244108b3bd73006143f15b | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: The Ehlers-Danlos syndromes (EDS) are a group of connective tissue disorders characterized by triad of joint hypermobility, skin extensibility, and tissue fragility. Ehlers-Danlos syndrome type IV places patients at risk for life-threatening, spontaneous, vascular or visceral rupture due to reduced or abnormal secretion of type III collagen. We present an adolescent male who was found to have a perisigmoid abscess with a fistula connecting to adjacent sigmoid colon secondary to undiagnosed EDS type IV. Conservative management with antibiotics and bowel rest was pursued to allow for elective resection for his acute complicated diverticulitis at a safer time.
Question: What tissue is most affected in Ehlers-Danlos syndromes? | [
"connective tissue"
] | task469-3d07390a15244a999c3ef7bc78ec9eb3 | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Recently the relevance of Simpson resection grade as a prognostic factor for recurrence of WHO Grade I meningiomas was challenged, contradicting many previous scientific reports and traditional neurosurgical teaching. The objective of this study was to determine whether the predictive value of Simpson resection grade is outdated or remains valid with respect to meningioma recurrence and overall survival. All patients at least 16 years old who underwent primary craniotomies for convexity meningiomas at Oslo University-affiliated hospitals (Rikshospitalet and Ulleval University Hospitals) in the period between January 1, 1990, and January 27, 2011, were included. Overall survival and retreatment-free survival rates were correlated with patient- and surgery-specific factors. Three hundred ninety-one consecutive patients were included in the study. The median patient age was 60.1 years (range 19-92 years). The female-to-male ratio was 2.1:1. The WHO grades were Grade I in 353 (90.3%), Grade II in 22 (5.6%), and Grade III in 16 (4.1%). The follow-up rate was 100%. Median follow-up time was 7.1 years (range 0.0-20.9 years) and total observation time was 3147 patient-years. The 1-, 5-, and 10-year overall survival rates were 96%, 89%, and 78%, respectively. Age, sex, WHO grade, and Simpson grade were significantly associated with overall survival. The 1-, 5-, and 10-year retreatment-free survival rates were 99%, 94%, and 90%, respectively. Simpson resection grade and WHO grade were significantly associated with retreatment-free survival. The hazard ratios for retreatment after combined Simpson resection Grades II+III and IV+V were 4.9- and 13.2-times higher than after Simpson Grade I resection, respectively. Simpson Grade I resection should continue to be the goal for convexity meningiomas.
Question: Simpson grading is used to describe resection of which brain tumor? | [
"meningioma"
] | task469-3100abbb966240698b7b89e58fa4ab6d | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Context: Marks of Identity (Spanish: Senas de identidad) is a 1966 novel by the Spanish writer Juan Goytisolo.
Question: Who was the auther of Marks of Identity? | [
"juan goytisolo"
] | task469-1f61dd4ecdce4bce8031b1e344c8c4da | question_answering | [
"Wikipedia",
"News",
"Natural Science"
] | mrqa | task469_mrqa_answer_generation | english |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.