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We describe the clinical response, as determined by increases in total Hb and decreased transfusion needs, in five patients with thalassemia intermedia treated with HU alone or in combination with SPB.
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Three patients (five eyes) with intraocular lymphoma were also treated with a 1 mg injection of rituximab.
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We present a case of the syndrome of inappropriate antidiuretic hormone (SIADH) secondary to cisplatin therapy in a patient with advanced-stage large cell neuroendocrine carcinoma of the cervix.
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Positive reaction were obtained to captopril at 4 days and the others test being negative.
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Some patients develop hypersensitivity rash in response to HCQ.
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Polyarthritis, hepatitis and anti-native DNA antibodies after treatment with ethambutol and rifampicin.
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Two patients with ovarian cancer who had received multiple courses of cisplatin without complications experienced hypersensitivity reactions to cisplatin: one, involving intrahepatic artery infusion, manifested general erythema, dyspnea, and hypotension; the other, involving intravenous infusion, manifested abdominal pain, general erythema, and fever.
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Following 7 days of tigecycline she developed severe abdominal pain and elevated pancreatic enzymes suggesting acute pancreatitis.
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A 32-year-old white woman with major depression was treated with venlafaxine for 3 years.
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Anesthesiologists and surgeons should be aware of this uncommon complication than can occur with the use of peritonsillar bupivacaine infiltration for pain control in tonsil surgery.
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The degree of emanating clinical events also conforms to status of the aflatoxicosis.
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To our knowledge, this case report represents only the third description of laxative-induced TEN.
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KW-2149 is a new, semisynthetic, C-7-N-substituted, mitomycin C (MMC) analog showing equal or superior antitumor activity in both in vitro and in vivo assays.
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We describe 2 patients with severe erosive rheumatoid arthritis and rheumatoid vasculitis, respectively, in whom infliximab therapy was associated with peripheral neuropathy due to necrotizing vasculitis in one patient and to progression of preexisting mononeuritis multiplex in the other.
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Long-acting somatostatin analogues such as SMS 201-995 (Sandoz) are being evaluated in a wide range of clinical indications, including gut neuroendocrine tumours and acrogemaly.
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Real-time ultrasound imaging prevented inadvertent injury to the esophagus as well as the thyroid gland and vessels.
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Four of the six experienced renal failure requiring dialysis.
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He developed recurrent skin rash, fever, hypereosinophilia, and acute renal failure after rechallenge with chlorambucil.
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Patients who developed this syndrome did not differ from other patients in baseline ratings on the Brief Psychiatric Rating Scale (BPRS) and the Scale for the Assessment of Negative Symptoms, except that patients who developed the syndrome had a significantly higher mean baseline rating on the BPRS anxiety subscale.
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Diabetic symptoms dominated the clinical presentation but there was no tendency towards diabetic ketoacidosis.
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Mineral oil, a hydrocarbon, may not elicit a normal protective cough reflex and may impair mucociliary transport.
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Chlorpropamide-induced hemolytic anemia.
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Well-fixed metal-metal hip resurfacing components are removed for infection, instability, or hypersensitivity reactions.
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In patients with swallowing dysfunction and pneumonia, a history of mineral oil use should be obtained and a diagnosis of ELP should be considered in the differential diagnoses if mineral oil use has occurred.
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Caution in longterm usage and early recognition of pentazocine toxicity as a neuromuscular complication are important in order to prevent irreversible drug-induced fibrous myopathy and localized neuropathy.
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CONCLUSION: Our investigations indicated that oxaliplatin interacted with both an IgG antibody and a RBC membrane epitope probably located on the Band 3 anion channel.
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The mechanism, causes, and significance of disulfiram-like reactions are discussed.
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The increasing number of Latinos in the United States and the extensive cross-border transfer of medicines raise concerns that metamizole use and associated complications may become more frequent.
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The authors describe a case of valvular heart disease in a 48-year-old woman receiving benfluorex (150 mg t.i.d. for 8 years) and leading to surgical mitral valve replacement.
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We consider that the MAHA in this patient is chemotherapy-related.
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A woman who had a deep scar on her left arm as a result of an influenza vaccination was treated with insulin.
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Neither a complication nor clinical or radiological sequelae occurred in this patient.
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Although heparin-dependent antibodies (HDAs) typically manifest with thrombocytopenia as in heparin-induced thrombocytopenia (HIT), they may also manifest with preserved platelet counts.
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This finding suggests that conversion of ischemic to hemorrhagic infarction may occur even with appropriate and carefully administered anticoagulation therapy.
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A 77-year-old man developed ankle, hand, and facial swelling 2 weeks after starting rosiglitazone.
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A search of the United States Food and Drug Administration's Adverse Event Reporting System identified nine cases of oxcarbazepine-associated angioedema in pediatric patients aged 16 years and younger.
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Fluconazole in the treatment of candida peritonitis in continuous ambulatory peritoneal dialysis: report of a case.
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By the time of treatment stabilization, the patient had not experienced any further fits.
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Disopyramide-induced heart block.
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These finding indicate the possibility that the ileus was triggered by drugs with anticholinergic properties in this elderly diabetic patient treated with alpha-glucosidase inhibitors.
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Acute erythroid leukemia after cyclophosphamide therapy for multiple myeloma: report of two cases.
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The 5 neonates with antral hyperplasia had received prostaglandin E1 for longer periods (mean [+/- SD] duration, 569 +/- 341 hours) than the 65 normal neonates (54 +/- 58 hours, P less than 0.001) or the 4 neonates with clinical signs of gastric obstruction (119 +/- 60 hours, P less than 0.05).
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In this case, discontinuing piroxicam, a nonsteroidal anti-inflammatory drug, and starting a palliative treatment plan helped resolve a patient's ulcers.
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Allergy to cloxacillin with normal tolerance to amoxicillin and cefuroxime.
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Median performance status (SWOG) was 2 (1 to 3), and clinical presentations included nephrotic syndrome (n = 1), symptomatic cardiomyopathy (n = 1), gastrointestinal involvement with polyneuropathy (n = 2), and hepatomegaly (n = 1).
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Pentacam analysis may serve as a useful adjunct in following the progression of herpetic reactivation cases.
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Intra-arterial adriamycin chemotherapy for bladder cancer.
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OBJECTIVE: To report 2 cases of serotonin syndrome with serious extrapyramidal movement disorders occurring when metoclopramide was coadministered with sertraline or venlafaxine.
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Neuroleptic malignant syndrome is easily confused with other health problems; distinctions between it and malignant hyperthermia, heatstroke, and lethal catatonia are made.
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There was only a short term exposure to classic antipsychotics prior to risperidone administration.
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The seizures started when he was 2 months old.
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PATIENT AND METHOD: A 34-year-old woman with chronic hepatitis C, genotype 3, receiving pegylated interferon alpha-2a and ribavirin for 6 months, developed progressive malaise and anemia 6 months after the end of treatment.
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In patients with metastatic disease who had high levels of gastrin, SMS treatment for 5 to 24 months did not inhibit tumor growth or decrease gastrin levels.
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The incidence of cerebral amyloid angiopathy increases with advancing age.
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More than 4 years later, the patient continues to be troubled by persistent paraparesis and chronic pain.
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Selective catheterization of the tumor vessels is the established standard in TACE.
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Pulmonary infiltrates and skin pigmentation associated with sulfasalazine.
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OBJECTIVES: To present a very rare case of orally ingested sex hormone pills inducing nondurally attached meningioma in the lumbosacral region.
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The first patient developed mild nitritoid symptoms and pain in a band-like distribution, corresponding to T10-T12 dermatomes, shortly after gold sodium thiomalate (GSTM) injection.
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One of the antimalarials which has been highlighted for its effectiveness is halofantrine.
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Shortly after chemotherapy and an injection of pegfilgrastim, the patient developed poorly defined, rapidly progressive erythema, edema, and pain in his right forearm.
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A patient developed restless legs symptoms paralleling the course of interferon-alpha (IFN alpha) therapy for chronic hepatitis C.
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The authors describe a case of interstitial granulomatous dermatitis associated with darifenacin.
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Despite the lowest plasma osmolality, detectable levels of circulating ADH were present.
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Two patients with ovarian cancer who had received multiple courses of cisplatin without complications experienced hypersensitivity reactions to cisplatin: one, involving intrahepatic artery infusion, manifested general erythema, dyspnea, and hypotension; the other, involving intravenous infusion, manifested abdominal pain, general erythema, and fever.
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We report the case of a 40-year-old woman who developed fulminant hepatic failure and aplastic anaemia following a course of oral flucloxacillin.
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Patients treated with L-asparaginase may present with hemorrhagic and thrombotic cerebrovascular events.
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The patient then suffered from sudden left chest pain and dyspnea.
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Medical or surgical therapy is variably successful in these men.
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The group mean Karnofsky score increased from 76 before to 86.6 after therapy, indicating that with r-HuEPO treatment subjects were able to exert themselves to perform ordinary activities.
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Clinical effects from accumulation of morphine-6-glucuronide have not been described with the exception of case reports in which patients with renal failure were noted to develop opioid toxicity with high plasma levels of the metabolite and low levels of the parent drug.
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This case suggests that acute pancreatitis was due to intolerance of high-concentration lipid emulsion.
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White clot syndrome and continuous arteriovenous haemofiltration.
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Shortly after mizoribin withdrawal, his serum Na increased significantly from 128 to 139 mEq/l and plasma osmolality from 265 to 287 mosm/kg.
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RESULTS: Four patients experienced ventricular free wall rupture after having a MI between November 17, 1993, and July 28, 1995.
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The application of PCR-Restriction Enzyme Analysis (REA) method on cutaneous specimens in veterinary medicine is an extremely interesting diagnostic tool.
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We hypothesize that decreased renal elimination of MTX induced by the COX-2 inhibitor resulted in enhanced hematopoietic toxicity and immunosuppression causing the EBV-associated lymphoproliferative disease.
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And the importance of instituting prompt diagnosis and proper treatment should also be stressed.
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CASE REPORT: 1.5 years after resection, hyperfractionated radiotherapy and chemotherapy of an anaplastic ependymoma in the right parietal region, the cranial MRI of an 11-year-old girl showed multiple small contrast-enhanced lesions in the frontal cortex.
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Previous reports of warfarin resistance implicated older enteral feeding products with a much higher vitamin K content.
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BAL fluid also grew Mycobacterium kansasii, for which he received combination anti-mycobacterial therapy.
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The patient was otherwise healthy and taking no medication.
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CONCLUSION: Although BCG is considered a very effective treatment; consensus exists that not every patient with superficial bladder cancer should be treated with BCG due to its increased risk of toxicity.
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10 months later all studied cells in the marrow contained this deletion.
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CONCLUSION: We conclude that stanozolol is a safe and effective treatment of the cutaneous manifestations of cryofibrinogenemia.
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We report an additional case of isotretinoin teratogenicity in which the patient had agenesis of the cerebellar vermis, multiple leptomeningeal neuroglial heterotopias, hydrocephalus, and abnormalities of the corticospinal tracts.
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With a single 0.2 mg/kg dose of rasburicase, the serum urate level normalized and the infant completed therapy without incident.
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CONCLUSIONS: This is the first report of occurrence of scleromyxedema in a patient with MS.
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Clinical improvement has outlasted suppression of VIP secretion (suggesting an additional direct antisecretory action of SMS 201-995) and has occurred despite expansion of hepatic metastases.
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Gynecomastia developed in two epileptic patients some months after the addition of oral fluoresone 750 mg daily to the phenobarbital and phenytoin already being administered.
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A 44-year-old woman is described in whom amiodarone, disopyramide, and quinidine, administered alone separately, induced atypical ventricular tachycardia (AVT, torsade de pointes).
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Eight cases of pellagra, diagnosed on the grounds of neuropathological findings and retrospective study of clinical data, were found among 106 necropsy cases of tuberculosis.
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We report a case of reversible DKA and new-onset DM that developed in a demented patient who was treated with quetiapine for 14 days.
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We present a unique case of extensive BRONJ involving the maxilla, sinuses, and skull base, complicated by sinusitis and an intracranial abscess.
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This is the first case of HBV reactivation occurring during the year following rituximab monotherapy in the absence of any other immunosuppressive factor.
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RESULTS: Disconnection or damage of the catheter leading to leakage of baclofen into the lumbar swelling could be ruled out by the use of an indium (111) DTPA flow study.
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The probable additive toxicity of both agents on the pulmonary tissue is discussed.
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Hence, desensitization would be essential and may be accomplished successfully using the protocol described in this report.
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In many cases neutropenic enterocolitis is confined to the cecum, but the entire colon is sometimes involved.
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Recurrent Listeria monocytogenes bacteraemia in a liver transplant patient.
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