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Possible pathophysiological mechanisms which may have been operative in this case include: a direct central nervous system (CNS) toxic effect of valproic acid; a paradoxical epileptogenic effect secondary to the drug; and an indirect CNS toxic effect mediated through valproic acid-induced hyperammonemia.
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Serum electrolyte and creatinine levels remained within normal limits.
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Fourteen months after the second stenting, a new elective angiogram was performed without evidence of in-stent restenosis.
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CASE SUMMARY: A 65-year-old patient chronically treated with the selective serotonin reuptake inhibitor (SSRI) citalopram developed confusion, agitation, tachycardia, tremors, myoclonic jerks and unsteady gait, consistent with serotonin syndrome, following initiation of fentanyl, and all symptoms and signs resolved following discontinuation of fentanyl.
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To the best of our knowledge no comparable case and no discussion of possible complications of aspirin prophylaxis in patients with brain tumours have been published.
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After discontinuing the HCQ, the QT interval was shorter and the patient recovered after treatment with lidocaine and isoproterenol.
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Methysergide-induced retroperitoneal fibrosis: successful outcome and two new laboratory features.
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Cystoid macular edema responds to intravitreal triamcinolone and rebounds after intravitreal bevacizumab.
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We report a 7 year old boy, who developed clinical and echocardiographical findings of pericardial constriction 5 weeks after a cardiac surgery, which resolved with steroid therapy.
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We report four cases of hemodynamically significant pericardial effusion in patients with refractory lymphoma who were receiving gemcitabine, all of whom had a history of mediastinal radiation without subcarinal blocking.
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Chronic photosensitivity associated with hydrochlorothiazide ingestion occurred in four patients.
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Botulinum toxin for palliative treatment of epiphora in a patient with canalicular obstruction.
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Administration of intravenous nitroglycerin in a patient with idiopathic pulmonary hypertension resulted in an increase in pulmonary artery pressure associated with a decrease in blood flow that is best explained by an increase in pulmonary vascular resistance.
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By means of the in vitro heparin-induced platelet activation (HIPA) assay it was shown that standard heparin and the LMW heparins Fragmin and Fraxiparin (Sanofi Labaz, Munich, FRG), as well as the enoxaparine Clexane (Nattermann, Cologne, FRG), all induced platelet activation with the patient's serum.
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Further injections were followed by similar symptoms in addition to paraesthesiae and altered pin-prick sensation of anterior thigh and legs with no residual deficit.
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High-dose corticosteroids were given with a return to baseline pulmonary function.
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We report a case of a 35-year old female who developed new onset type II diabetes mellitus with hyperosmolar hyperglycaemic coma and acute renal failure following treatment with a SGA for a first manic episode.
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The two middle aged women presented with respiratory symptoms after prolonged treatment with nitrofurantoin.
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MANAGEMENT: Potassium supplementation, sodium bicarbonate therapy, intravenous fluid therapy and dialysis.
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The pharmaceutical company producing Halfan has reported 8 cardiac arrests, leading to 6 deaths, when a higher dose than recommended was used, there was recent or concomitant treatment with mefloquine, there was pre-existing prolongation of the QT interval or the patient had a thiamine deficiency.
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Although there is a presumed drug-drug interaction between itraconazole and nonnucleoside reverse-transcriptase inhibitors, the medical literature lacks such documentation.
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Analysis and correlation of antenatal data and drug therapy with individual cases failed to show any specific abnormality that could reasonably be attributed to zidovudine therapy.
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METHODS: A 68-year-old man developed intense conjunctival hyperemia and cystoid macula edema after switching from latanoprost to bimatoprost 9 months after cataract surgery in an eye at low-risk for this cystoid macular edema.
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Synergistic effect of carbapenem-teicoplanin combination during severe Rhodococcus equi pneumonia in a kidney transplant recipient.
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The considerable exposure to chemicals, time course and unusual pattern of organ involvement suggested a diagnosis of occupational scleroderma.
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When prescribing mannitol to decrease intraocular pressure, the physician must be alert to potential complications.
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These symptoms did not recur after discontinuation of the drug.
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Once the diagnosis of acute cerebral infarction is confirmed, thrombolytic therapy should be administrated within the time window of 3 hours.
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They have lipid levels drawn annually and are seen by both an endocrinologist and a flight surgeon for general medical examinations.
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CASE SUMMARY: A 66-year-old man with a background history of breast carcinoma was admitted with pleuritic chest pain.
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Neuroleptic malignant syndrome in an adolescent receiving olanzapine-lithium combination therapy.
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Fifteen patients presented between January 1986 and January 1991 with deterioration in renal function coincident with the introduction of angiotensin converting enzyme inhibitors.
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While both amiodarone and digoxin can cause permanent visual changes, the ocular effects are often reversible.
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Iatrogenic hypercalcemia due to vitamin D3 ointment (1,24(OH)2D3) combined with thiazide diuretics in a case of psoriasis.
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BACKGROUND: The antimycotic synthetic azole compounds are known to lead to toxic liver injury.
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Gadolinium enhancement of anterior lumbosacral spinal nerve roots was demonstrated in all three patients, and an elevation of cerebrospinal fluid immunoglobulin G synthesis was evident in two patients with more severe symptoms.
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Pulmonary leukostasis secondary to all-trans retinoic acid in the treatment of acute promyelocytic leukemia in first relapse.
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A wide range of autoimmune disorders have been described in DiGeorge syndrome and velocardiofacial syndrome, including one prior report of autoimmune hemolytic anemia and immune thrombocytopenia.
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Steroid therapy improved the airways of the other 8 patients.
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Better appetite was subjectively noted by 81% of patients.
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Concurrent use of reteplase and lepirudin in the treatment of acute anterior wall myocardial infarction.
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However, brain metastasis was diagnosed.
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The patient presented to the emergency department with a few weeks' history of irritability, constipation and intermittent vomiting.
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In patients with occult hepatitis B virus (HBV) infection, acute exacerbation may occur when they become immunocompromised.
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Aliskiren-associated acute renal failure with hyperkalemia.
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We discuss the potential mechanisms associated to OXC and status migrainosus, drug-induced headaches and uncontrolled headaches.
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Laryngeal dyspnea in relation to an interaction between acenocoumarol and topical econazole lotion.
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We report the first case of fulminant adult respiratory distress syndrome (ARDS) associated with pegylated interferon alpha-2a (pegIFNalpha-2a) and ribavirin use for hepatitis C, complicated by subsequent and ultimately fatal sepsis and multiorgan failure.
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Both recovered after 10 days of intraperitoneal administration of cefazolin and tobramycin.
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Five days after discharge (day 1), she developed bilateral lower extremity arterial thrombi and underwent heparinization and successful lower extremity thrombectomies.
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Infliximab and its serious adverse effects are discussed, and other cases of osteomyelitis with infliximab use are also reviewed.
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Treatment with ketamine met with moderate success, and then large doses of lorazepam and midazalam were used.
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Abemayor).
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OBJECTIVE: To evaluate the simple medication regimen, all psychotropics were given at night for patients with chronic schizophrenia, who had been taking them at least twice a day for more than 12 weeks before the entry.
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We describe the clinical course, renal function, and blood viral measurement in 6 renal transplant recipients with BKVN who were treated with low doses of cidofovir.
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Imaging findings were compatible with left maxillary, ethmoidal, and sphenoidal sinusitis.
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It is not certain to what extent drug therapy, physiological and metabolic changes consequent on prolonged seizures, hitherto undiscovered infective agents, or a combination of any of these may play in such a process.
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Before desensitization, the proportion of CFSElow CD4+ cells in whole CD4+ was 3.09%; 13.6% of CFSElow CD4+ cells were stained with anti-interferon gamma antibody.
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A 56-year-old white woman with a diagnosis of reactive depression developed severe UI after a 30 days' treatment with venlafaxine 75 mg/day.
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In this report, a patient who had undergone a renal transplantation as a result of malignant hypertension, and who was on immunosuppressive therapy consisting of cyclosporin, prednisone and azathioprine, developed thrombosis of the central retinal vein 5 years following the transplantation.
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OBJECTIVE: To document a case of serotonin syndrome (SS) associated with mirtazapine monotherapy, review the previously reported cases of SS associated with this tetracyclic antidepressant, and discuss the possible pathogenic mechanisms leading to this serious adverse drug reaction.
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We demonstrate linezolid's high CSF penetration and its CSF bacteriostatic activity against E. faecalis.
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A 47-year-old male with bipolar I disorder/hallucinations presented to the Veterans Affairs Medical Center (VAMC) with suicidal ideations.
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The authors describe a woman with chronic schizophrenia who experienced delirium, grand mal seizure, and photosensitivity after the addition of propranolol to her neuroleptic regimen.
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They are usually localized reactions such as ecchymoses, erythematous plaques, and nodules.
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The nasal challenge test with a calcitonin nasal spray, up to 150 UI, was negative.
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We present a case of hemolytic-uremic syndrome that developed during the 4th cycle of combination chemotherapy with oxaliplatin, 5-fluorouracil and leucovorin.
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Diagnosis of DPD deficiency must be confirmed by specialized laboratory tests.
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Her best-corrected visual acuity was 0.9 in the right (RE) and 1.0 in the left eye (LE).
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Cytogenetic studies of the bone marrow performed after the development of acute leukemia showed chromosome abnormalities in all five patients examined, with hypodiploidy and loss of B and C group chromosomes.
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Diagnosis of toxoplasmosis was confirmed by muscle biopsy and seroconversion.
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Two patients with imminent gangrene of the extremities caused by ergot-induced arteriospasm underwent mechanical dilatation of the arteries when conventional measures such as anticoagulation, vasodilation, and sympathetic blockade produced no improvement.
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METHOD: In an effort to refine MAOI dietary recommendations, we report a case of hypertensive crisis following the consumption of a modest amount of tap beer.
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The use of methotrexate (MTX) has been contraindicated for treatment of severe psoriasis in HIV infection on the basis of six previously reported cases in which MTX appeared to potentiate opportunistic infections and accelerate HIV disease.
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Two separate blood cultures yielded C. indologenes.
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Fungal peritonitis in patients on continuous ambulatory peritoneal dialysis (CAPD) has been associated with high mortality and high CAPD-discontinuation rates.
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CONCLUSIONS: This is the second case report that describes gemcitabine-induced radiation recall in rectus abdominus muscles after gemcitabine-based radiation therapy.
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Hypoxia was documented in one case and probably present in the other.
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Broad-spectrum antibiotic therapy and percutaneous abscess drainage under the guidance of computed tomography resulted in a satisfactory resolution of the abscess.
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This potential long-term risk has medicolegal implications for informed consent and for the potential use of both permanent fillers and interferon.
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On the third day, zafirlukast (20 mg twice daily) was reintroduced to the regimen, and the theophylline therapy was continued.
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The overall toxicity is substantially less than standard induction chemotherapy, with the notable exception of deaths attributed to the development of pulmonary leukostasis coinciding with a rapid increase in the number of mature neutrophils.
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It is of interest that all of his teeth were extremely large and subsequently showed severe crowding in the dental arches.
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METHODS: We present the clinical and laboratory findings and describe the clinical course of our patient.
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The reversal of symptoms and radiographic demonstration of relief of obstruction after oral steroid therapy are discussed.
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Although the possibility of this interaction has been noted, no previously documented occurrence of this interaction has been identified.
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The chimeric anti-CD20 monoclonal antibody, rituximab, is a promising treatment for cutaneous B-cell lymphomas.
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Review of the current literature confirms the importance of 3D dose planning in avoiding this complication and high-lights the role of MRI in establishing the diagnosis of radiation-induced optic neuropathy.
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Clinicians have been aware of lithium toxicity for many years and traditionally have administered thiazide diuretics for lithium-induced polyuria and nephrogenic diabetes insipidus.
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METHODS: No reports describing alcohol neurolysis of the superior cluneal nerve exist in the relevant literature.
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CONCLUSION: To our knowledge, this is the first case report of delayed onset of cerebral infarction caused by an embolism after CPS fixation.
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INTRODUCTION: Significant decreases in tumour recurrence rates of up to 50% are reported after one immediate postoperative instillation of chemotherapeutic drugs, such as epirubicin or mitomycin C.
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Thiazolidinedione-induced edema.
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Biopsy taken from the site did not reveal any granulomatous or atrophic changes and cultures of the biopsy did not yield any organism.
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Post-transfusion purpura as the main manifestation of a trilineal transfusion reaction, responsive to steroids: flow-cytometric investigation of granulocyte and platelet antibodies.
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After the remission of the hypoalbuminemia and thrombocytopenia, the macular edema observed by OCT disappeared and visual acuity returned to normal.
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Cerebral angiography disclosed occlusions and narrowing of both internal carotid arteries at the supraclinoid portions, where multiple cysts were found on the MRI.
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Behavioral side effects associated with clonazepam may include agitation, aggression, hyperactivity, irritability, property destruction, and temper tantrums.
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Additional drugs present included hydrocodone and morphine (nonconjugated) at 0.16 and 0.04 microg/mL, respectively.
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Possible interactions between the putatively hyperactive dopaminergic system and corticosteroids are discussed.
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