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Allele-specific polymerase chain reaction (PCR)-based methods are now available for genotyping using leukocyte DNA.
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PURPOSE: To present a case of recurrent postoperative endophthalmitis with a scleral-tunnel abscess and adjacent microbial keratitis.
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It occasionally accompanies the heparin-associated thrombocytopenia and thrombosis syndrome.
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Cerebral edema associated with Gliadel wafers: two case studies.
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Such abuse (possibly linked to the rewarding effect of dopamine) has been recently monitored in the context of Parkinson's disease (PD) (the "dopamine dysregulation syndrome").
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Restless legs syndrome due to interferon-alpha.
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For one patient, thrombocytopenia due to autoantibodies to PEG-rHuMGDF developed shortly after PEG-rHuMGDF administration and persisted until chemotherapy was administered.
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BACKGROUND: Diverse complications have been reported in association with the growth and medical treatment of uterine leiomyomata.
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Repeat PTCA was performed 10 days postdischarge due to intraluminal stent occlusion.
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The patient had several acute sinusitis and septic episodes during his acute course.
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However, a cross-correlation analysis indicated that TPO responses preceded platelet responses by approximately one day in all patients.
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Severe hypertension in newborn after pyeloplasty of hydronephrotic kidney.
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The following day the vulvar edema had increased and spread to the sacrum.
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Equine-derived antivenin was given in 14 cases (range 2-30 vials).
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Case report and review of the literature.
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After 46 days of treatment, radiography showed cortical hyperostosis of the long bones.
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Three patients, in whom tumour overkill by cytotoxic treatment, including high dose methotrexate with folinic acid rescue, resulted in the 'phosphate shower syndrome' (hyper-uricaemia, hyperkalaemia and hyperphosphataemia with hypocalcaemia and tetany, with metabolic acidosis and acute renal impairment) are described.
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Nitrendipine-induced gingival hyperplasia.
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Classic neuroleptic malignant syndrome (NMS) was diagnosed.
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In addition to our reported cases, 5 cases of nephrotic syndrome in similar patients reported elsewhere are analyzed together with our cohort.
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Cardiorespiratory toxicity due to miconazole.
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Heparin therapy for mistaken cardiac diagnosis in Boerhaave's syndrome.
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The sub-conjunctival haematoma in a patient receiving warfarin can pose a significant management challenge.
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Platelet recovery and clinical improvement coincided with administration of rituximab.
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Although the efficacy of recombinant factor VIIa has been shown in many patients, concerns have arisen about the risk of thrombotic adverse events.
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The usefulness of CYP2C9 genotyping before starting coumarinic treatments is discussed.
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The immunoglobulin serum levels and inflammatory markers were unchanged.
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Clinical features were those of a cicatricial pemphigoid, with prominent mucosal involvement leading to conjunctival and nasal scarring.
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This is in contrast to similar symptoms reported by only 8 percent of a control population.
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We describe the implications of these cases for the use of immunomodulatory therapy in CD and the questionable association between CD and lymphoma.
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During two courses of cytostatic drug administration peak and trough plasma levels of phenytoin, carbamazepine, and valproate sodium were measured.
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A moderate vitreous hemorrhage occurred four days after PDT.
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METHOD: Case analysis of a poly-drug overdose (venlafaxine, topiramate, divalproex sodium, risperidone, and carbamazepine) presenting with mixed SS/NMS features and whose clinical management suggests a practical algorithm for treatment of undifferentiated SS/NMS in critical care settings.
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This case suggests that chemotherapy with its attendant immunosuppression is a predisposing factor in the development of necrotizing fasciitis and warrants a high index of suspicion.
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In a randomized trial, we compared the efficacy and toxicity of azithromycin and ceftibuten once daily in the initial (empiric) therapy of proven or suspected community-acquired respiratory tract infections (CARTI) in 163 pediatric patients: 95.5% of those treated with azithromycin and 83.6% of those treated with ceftibuten were cured or improved.
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Limited documentation of this adverse effect exists in the literature.
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Treatment was continued with amphotericin B colloidal dispersion, followed by fluconazole for 8 months.
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Although both drugs have been reported to preserve endogenous insulin secretion and to interrupt the diabetogenic process they may be responsible for diabetes and exocrine pancreatic insufficiency in our patient.
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Ankylosing spondylitis was present in two patients, but no other extraintestinal manifestations developed.
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We present a case of an elderly patient with systemic lupus erythematosus diagnosed more than 40 years ago, who suffered from recurrent fractures and attendant complications despite a bone mineral density (BMD) score in the osteopenic range and treatment with bisphosphonates.
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It remains to be seen whether the hepatotoxicity associated with troglitazone is a drug-class effect or specific to troglitazone.
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Following steroid withdrawal and institution of gammaglobulin, the patient grew 6 inches within 2 years, regaining his vision, retrieving his stature, and normalizing his psychosocial development.
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The authors describe a relation between the in vivo localized consumption of In-111 platelets and results of laboratory tests in a 82-year-old man with an aortic graft prosthesis who had chronic disseminated intravascular coagulation.
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Ordinarily occurring as a commensal, Kluyvera have been reported to cause serious infections in immunosuppressed and immunocompetent hosts, causing diarrhea, urinary infections, peritonitis, and cholecystitis.
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Improvements in sexual function (62%), socializing (70%), sleep (68%), and skin color (51%) were also noted.
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The second organism has not previously been reported in a subphrenic abscess.
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Similar symptoms developed after each challenge and resolved after discontinuing this preparation.
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However, in the rare case of postoperative patch leakage, a relapse of a pseudoaneurysm may occur.
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Pulmonary toxicity with mefloquine.
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Acute myocardial infarction associated with systemic lupus erythematosus documented by coronary arteriograms.
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Six days after she received a prescription for a 5-day course of azithromycin, her INR was 15.16.
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Exacerbations of the heart failure were temporally related to the administration of the antitumor antibiotics actinomycin-D (NSC-3053) and mithramycin (NSC-24559).
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He had a history of hypertension and uremia.
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Pulmonary fibrosis associated with nabumetone.
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RESULTS: After 4- to 14-month period of therapy with the combination of indapamide (2.5 mg/day) and fosinopril (10 mg/day) in three patients and 6-month period of monotherapy with indapamide (2.5 mg/day) in one patient, glucose levels of all patients increased and achieve criteria of diabetes diagnoses.
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Immunosuppression related to HIV infection, immunosuppressive treatment, organ transplantation, and neoplastic diseases increases the risk for Leishmania-infected people to develop visceral illness.
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Contact dermatitis, an inflammatory response of the skin to an irritant or an allergen, can affect hospital staff.
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Donepezil for behavioural disorders associated with Lewy bodies: a case series.
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A left L1 transforaminal approach was successful, and 1 mL of iopamidol (Isovue) contrast was injected, followed by 5 mL of a solution of 0.125% bupivacaine and 40 mg of triamcinolone.
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There is no information to support the possibility of increase risk of late pregnancy complications or change in the natural course of the disease.
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Moreover, because the patterns of response to ipilimumab differ from chemotherapy, we need to understand how and when patients may respond to treatment so that appropriate clinical decisions can be made.
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Two cases of lepromatous leprosy with erythema nodosum leprosum who were on high doses of clofazimine, showed discoloration of nail plate, subungual hyperkeratosis and onycholysis.
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There was no clinical evidence of immunosuppression or any obstructive lesion in the esophagus.
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The lesions resolved completely approximately 30 min after removal of the hands from water.
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The carbonic anhydrase inhibitors that are used most frequently in ophthalmic practice are acetazolamide and methazolamide.
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"St. Anthony's fire" may be due to stimulation of alpha-adrenergic receptors in the peripheral vasculature.
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Digoxin serum levels and toxicity risks increase with the addition of amiodarone.
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Awareness of this route of intoxication might be important in patients in whom neurologic or psychiatric symptoms develop while large amounts of lidocaine cream are being used.
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In the brain, the following distribution of olanzapine was determined (mg/kg): negative (cerebellum), 0.22 (hippocampus), 0.86 (midbrain), 0.16 (amygdala), 0.39 (caudate/putamen), 0.17 (left frontal cortex), and 0.37 (right frontal cortex).
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We report a rare case of recurrent (stuttering) priapism in a patient with protein C deficiency while maintained on Warfarin therapy.
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Pathologic findings demonstrated on MR were (1) chronic brain edema, demonstrable over a period of 3-14 months (proved by autopsy in one patient); (2) multifocal white matter necrosis; and (3) deep brain atrophy.
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Usefulness and sensitivity of the neuro-otological examination in the field of dysequilibrium of central disorder as well as peripheral vestibular disorder is emphasized.
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An unusual course of infection with Mycobacterium malmoense is described in a patient receiving chronic but mild immunosuppressive therapy for rheumatoid arthritis.
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Puberty started at 11.2 years and menarche occurred at 12.7 years.
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Acarbose treatment of infant dumping syndrome: extensive study of glucose dynamics and long-term follow-up.
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The occurrence of this entity is linked to the presence of circulating leukoagglutinins.
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We report on a child with fatal valproate-related hepatotoxic effects despite this supplementation.
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Recommendations are made for the prophylaxis and treatment of sulfadiazine-related renal toxic reaction.
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We report on a patient with subarachnoid haemorrhage who developed an acute life-threatening pseudo-obstruction of the colon, a variant of adynamic ileus, while being treated with intravenous nimodipine.
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SUMMARY: A 26-year-old man with bipolar disorder, seizures, and mild mental retardation secondary to a traumatic brain injury began treatment with carbamazepine for aggression and seizure control.
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This case showed sequential manifestation from transient thyrotoxicosis to the appearance of TSH-receptor autoantibodies, and then the occurrence of Graves' hyperthyroidism during IFN therapy.
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CONCLUSIONS: Patients receiving intravitreal injections of bevacizumab should be evaluated for potential systemic risk factors such as carotid insufficiency, coagulopathy and poorly controlled diabetes mellitus.
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The prosthesis acts as a porous membrane which allows two opposite flows: the passage of blood from graft to bowel and germ migration from naturally septic bowel to blood.
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We report a premature infant who developed seizures associated with intraventricular administration of nafcillin and discuss the need for electroencephalographic monitoring of patients receiving intraventricular antibiotics.
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It has been suggested that quinolones may produce an epileptogenic effect by inhibiting the binding of gamma-aminobutyric acid to its receptor sites in the brain.
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Theophylline intoxication mimicking diabetic ketoacidosis in a child.
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We report a patient receiving chronic lithium therapy who presented with a transient CDI occurring in the setting of underlying chronic NDI.
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As with our patient, many of these case reports described clinicians who overlooked thrombosis due to HDAs because the patients did not have HIT.
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Low doses of topiramate are effective in essential tremor: a report of three cases.
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In our case, renal biopsy revealed diffuse proliferative glomerulonephritis with findings of active cellular immunity, and aggressive treatment resulted in attenuation of these findings.
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Diffuse alveolar hemorrhage after leflunomide therapy in a patient with rheumatoid arthritis.
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We report a case of hyponatremia associated with a grand mal seizure in a 28 month-old child after intra-nasal desmopressin administration for high fluid intake with nocturnal enuresis.
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However, alkylating agents overwhelmingly predominate as the class of compounds which are most often associated with terminal ANLL.
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We report a cae of paranoid psychosis following use of a decongestant containing PPA and summarize the case report literature of psychiatric adverse effects to PPA in which doses were known and stated to be within recommended guidelines.
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Bipolar disorders as well as recurrent major depressive episodes can be most effectively treated with electroconvulsive therapy (ECT).
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Desipramine and testicular swelling in two patients.
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This is the first report of an adverse effect of fetal renal circulation by maternal ingestion of nimesulide.
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Propylthiouracil-induced cutaneous vasculitis.
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Pneumocystis pneumonia should be considered in asthmatic patients taking methotrexate who present with fever, pulmonary infiltrates, and hypoxia.
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CONCLUSIONS: The value of multihormonal therapy in breast carcinoma is not established, and the addition of progestogens to tamoxifen may not reduce of developing endometrial lesions, including carcinoma.
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