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The drug was identified and quantitated in plasma and urine using an HPLC technique with diode-array detection.
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On discontinuation of the drug, serum CK concentrations returned to normal within eight days.
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Hycanthone is an antischistosomal drug with promising antitumor activity against experimental animal tumors.
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The multiple drug schema consisted of: Etoposide 16.213, Methotrexate, Cyclophosphamide, Actomycin-D, and Cisplatin.
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Over 20 years, 877 patients with Crohn's disease, 492 women (56.1%) and 385 men (43.9%), were evaluated with patient follow-up data available for a mean of 7.8 years.
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History revealed that the patient had taken a combination phenolphthalein/docusate sodium (Correctol) over-the-counter laxative 1 day prior to admission.
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Six of 13 outpatients with schizophrenia who participated in a ten-week open trial of risperidone had an initial good response to the medication followed by development of intolerable affect, including feelings of agitation and depression and periods of crying and insomnia.
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Severe systemic hypersensitivity reaction to ibuprofen occurring after prolonged therapy.
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Unexpectedly, liver function returned to normal on stopping the drug.
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Paraspinal muscle impingement causing acute Brown-Sequard syndrome after posterior cervical decompression.
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Administration of low-dose cidofovir was associated with clearance of BK virus DNA from blood and allograft, and stabilization of renal function in both patients, without significant toxicity.
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After rechallenge with monotherapy pegvisomant, however, the hepatic enzyme disturbances reappeared within a few weeks, indicating that most likely pegvisomant alone and not the long-acting somatostatin analog or the combination of these two drugs was responsible for this case of drug-induced hepatitis.
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Nephrotic range proteinuria gradually regressed after stoppage of local injection of IFN-beta without glucocorticoid treatment.
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Two cases of candidiasis occured in the stomach.
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Initial treatment for MN consisted in corticosteroids and immunosuppressors (ciclosporin, mycophenolate mofetil, rituximab, chlorambucil) in all patients.
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Findings of electrophysiologic study and cardiac magnetic resonance imaging were within normal limits, pointing to the ingestion of Aconitum as the most likely source of his arrhythmia.
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Two complications were identified (0.1%), one at each institution.
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The authors have encountered this entity in two patients who were deemed disease-free following combination chemotherapy for malignant disease.
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Molluscum contagiosum is a common viral skin infection in children with atopic diathesis and not rare in HIV patients.
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An encephalopathy and cardiomyopathy developed in a seventeen-year-old girl with chemotherapy-induced renal failure while receiving an intravesical aluminum infusion for hemorrhagic cystitis.
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In each case, 25-100 micrograms of intracoronary nitroglycerin promptly (30-45 seconds) resulted in reopacification of the vessel involved in spasm and resolution of evidence for ischemia.
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OBJECTIVE: To report a case of serotonin syndrome associated with interaction between fentanyl and citalopram, as evidenced by medication history, clinical features and reversal following discontinuation of fentanyl.
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No relationship was identified between the extent and the severity of the skin lesions with the phenytoin and radiation dosages and with the histologic type and origin of the intracranial malignancy.
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The patient expired after seven cycles of treatment had been completed because of pulmonary fibrosis and the drug toxicity of bleomycin.
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Treatment strategies involved use of antimicrobials and supporting the damaged multi-organs.
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Many types of skin disorders concomitantly occur with hepatitis C virus infection.
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After 8 months of administration of human insulin by a jet injector, there were no more new lesions of lipoatrophy and those affected areas were substantially ameliorated.
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Stenotrophomonas maltophilia (previously named Xanthomonas maltophilia) is an aerobic, nonfermentive, Gram-negative bacillus that is widespread in the environment.
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With the recent Women's Health Initiative Study demonstrating increased risk of breast cancer and cardiovascular events associated with hormone therapy, many women may resort to herbal remedies for persistent menopause symptoms.
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Macrophage activation syndrome in systemic juvenile rheumatoid arthritis successfully treated with cyclosporine.
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A forty-two year old female with known alcoholic liver disease was given intravenous lorazepam and diazepam for delirium tremens.
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These patients often experience acute intradialytic manifestations while non-pharmacologic interventions as pharmacologic agents are sometimes insufficient to improve symptoms.
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It is recommended that daily leukocyte counts be done in burn patients being treated with silver sulfadiazine.
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We report a case of a young woman with SLE and thrombocytopenia, who developed severe perspiration, headache, and seizure after receiving cyclosporine.
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We report the first case of doxycycline-induced hypoglycemia in a young nondiabetic man.
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Complete relief of pain was noted in 73% of patients during the treatment.
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CONCLUSION: This case and the results of the analyses are in accordance with the described problems and results published earlier.
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Pancreatitis has been associated with the tetracycline class of antibiotics and concerns about tigecycline-induced acute pancreatitis have recently been raised.
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BACKGROUND: Pemphigus is an autoimmune blistering disease of the skin and mucous membranes.
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All three patients had rheumatoid arthritis and had received chloroquine for between 12 and 18 months with a maximum dose of 250 mg/daily.
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After cessation of the sulfasalazine and completion of a six-week course of corticosteroids, these problems resolved over a period of four to six months.
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Retrospectively, bucillamine was believed to be the cause of the giant hypertrophy because of its structural similarity to D-penicillamine, which was the subject of an abundance of reports of mammary hyperplasia.
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Case Report: We report a case of methanol poisoning exhibiting complete recovery from severe visual impairment following treatment with ethanol, fomepizole, and hemodialysis.
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Viscoelastic material as an adjunct to dissections and to treat microperforations during nonpenetrating filtering surgery.
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The characteristics of the small subgroup of chronic anorexics, in whom the risk/benefit ratio may justify such a regime, are tentatively outlined.
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In addition, 1 of these biopsy specimens also had scattered single eosinophils, unlike autoimmune hepatitis.
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This article focuses on the methodological issues involved in choosing instruments to monitor behavior, once a comprehensive evaluation has suggested trials on Ritalin.
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Sustained ventricular tachycardia in a thalidomide-treated patient with primary plasma-cell leukemia.
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In a postural challenge test after administration of isosorbide dinitrate (5 mg), blood pressure decreased from 120/67 to 65/35 mmHg, followed by syncope with a sudden decrease in pulse rate from 85 to 60 beats/min.
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We report marked QT prolongation and torsades de pointes in a setting of flash pulmonary edema resulting from acute myocardial ischemia in a patient who was being treated with dofetilide for atrial fibrillation.
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We believe that immunosuppression-induced pneumonitis in a lung allograft is a serious dilemma for lung transplant physicians
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Echocardiogram showed normal left ventricular systolic function with mild mitral and tricuspid regurgitation and trace aortic insufficiency.
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Bone marrow aplasia and severe skin rash after a single low dose of methotrexate.
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The infant was given indomethacin to induce constriction of sPDA.
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The deletion results in decreased CYP2D6 activity, possibly leading to drug accumulation.
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BACKGROUND: This is the first communication of a fatal spontaneous spinal epidural hematoma following thrombolysis.
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Concentrated topical epinephrine is safe in endoscopic sinus surgery.
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A case of necrotizing fasciitis of the vulva arising in a leukemic patient during a chemotherapy nadir is presented.
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The third patient had been suffering from serious akathisia while on risperidone, and was cured after switching to olanzapine, but thereafter the patient suffered from RLS at nighttime.
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Tics and Tourette syndrome are common comorbidities of patients diagnosed with attention-deficit/hyperactivity disorder (ADHD).
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Laboratory determinations were used to directly evaluate therapeutic anticoagulant effects, and dosage regimens were adjusted to achieve desired anticoagulant levels.
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The pathogenetic mechanism of these symptoms might possibly be explained as potentiation of the action of the neuroleptica by oral antidiabetics.
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Life-threatening interstitial lung disease associated with trastuzumab: case report.
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Potential causes of methamphetamine-related keratitis can be divided into four categories resulting from (a) direct pharmacologic and physical effects of methamphetamine; (b) the toxic effects of diluting or "cutting" agents such as lidocaine and quinine; (c) effects related to the route of drug administration (intravenous, inhalation, smoking); and (d) manufacture-related effects of exposure to unintentional caustic contaminants in the final product.
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The association of venlafaxine treatment with ischaemic events could be explained by its unique pharmacological and haemodynamic properties.
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A 56-year-old Caucasian man who received concomitant chemotherapy and radiation for head and neck cancer developed fever concurrent with the administration of amifostine.
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Radiologic recognition of adriamycin cardiotoxicity.
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The lesions resolved after treatment with topical steroids and also oral allopurinol in one of the cases.
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The variation among different diagnostic criteria makes this syndrome a challenging diagnosis at times, in particular when atypical antipsychotics are suspected as the causative agent.
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Therefore, wide spectrum antibiotics were continued.
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Monitoring of liver function tests should be mandatory in patients receiving high doses of cyproterone acetate; the drug should be withdrawn immediately if abnormal liver function tests are found.
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The cause of hiccups should be expressly stated for treatment.
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Thrombotic thrombocytopenic purpura (TTP) developed in a patient with seropositive rheumatoid arthritis (RA) after 2 1/2 months of treatment with penicillamine.
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Spinal cord infarction during use of zolmitriptan: a case report.
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Few studies have been carried out regarding preoperative chemotherapy utilized in the treatment of primitive neuroectodermal tumors/medulloblastomas (PNET/MB).
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Multifocal osteomyelitis caused by Candida dubliniensis.
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We describe the clinical course of these patients and their management aimed at maximizing the effectiveness of gold therapy.
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Early onset of hemophagocytic syndrome following allogeneic bone marrow transplantation.
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The development of perianal fistulas in 2 patients, granuloma on biopsy in 1 patient and perianal skin tag in 1 patient, led to a diagnosis change of CD.
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Aminoglycoside-associated hypomagnesaemia in children with cystic fibrosis.
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Localized purpura associated with lamotrigine.
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All symptoms disappeared soon after stopping the drugs, though in two cases the papilloedema persisted for many months.
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The mean histologic activity index scores for patients in groups 1 and 2, respectively, were 6.7 and 5.4.
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Several cases of lithium-induced Creutzfeldt-Jakob syndrome have been reported to date; all of them were elderly patients and a half had "therapeutic" lithium serum levels.
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The absence of borderline mutations in the normal population, and the co-segregation of the expanded allele with neurological signs in one kindred suggest that SCA2 mutations may be responsible for a subset of familial parkinsonism.
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Laboratory evaluation ruled out the most common causes of fulminant hepatitis.
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Transient leucopenia and thrombocytopenia associated with sodium nitroprusside infusion.
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Voriconazole (VRC) has not previously been reported to cause angio-oedema.
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The risk is probably higher with valproic acid than carbamazepine.
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Although uncommon, exogenous lipoid pneumonia (ELP) should be considered when patients present with this symptom complex.
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Drug-induced interstitial nephritis in a child with idiopathic nephrotic syndrome.
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The reported effects of these agents in increasing total Hb, however, have been inconsistent and there have been no studies on the combination of these medications.
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They had not been transfusion-dependent prior to treatment.
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The occurrence of neuromuscular blockade and the resulting potentiation of muscle relaxants during magnesium sulfate (MgSO4) administration is well known.
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The patient had required two surgical decompressions of the right orbit to relieve pressure, which occurred secondary to progression of the exophthalmos, and was scheduled for further surgery.
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Intravenous epoprostenol was administered perioperatively to control the pulmonary hypertension in both instances.
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Dermatomyositis, complicated with pneumomediastinum, successfully treated with cyclosporine A: a case report and review of literature.
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Repeated blood transfusions were associated with rapidly evolving renal failure coupled with anemia and thrombocytopenia.
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How safe is our blood transfusion?
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The pathogenesis of autoimmune hepatitis entails complex interactions between triggering factors, autoantigens, genetic predisposition, and immunoregulatory networks.
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