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As is known, tamoxifen therapy is related to endometrial proliferation, hyperplasia, polyp formation, invasive carcinoma and uterine sarcoma.
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Contraindications for mannitol in aphakic glaucoma.
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Drug withdrawal resulted in a slow and progressive reduction in bilirubin levels and liver enzymes.
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Agitated dysphoria after late-onset loss of response to antidepressants: a case report.
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2 months later symptoms had resolved with a control CT of the thorax showing complete regression of the pulmonary changes.
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With the increased use of indwelling central venous catheters, increasing numbers of cases of Rhodotorula fungemia have been observed in patients with neoplasia and neutropenia.
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After several months, neither patient required antidiabetic treatment.
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A case may be made for the discontinuation of the usage of chloral hydrate.
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It also highlights a current major etiologic question, that is, whether and to what degree lead exposure contributes to the development of hypertension, and raises the issue of whether lead-induced hypertension constitutes a subset of hypertension that is especially amenable to therapy with dietary calcium.
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Eventually she showed apneic spells and hyperglycemia.
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Our purpose is to alert surgeons and therapists to a rare but potentially devastating complication and to provide our experience in treating it.
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Although useful in the management of chronic alcoholism, disulfiram is being increasingly associated with a wide spectrum of side effects and untoward medical sequelae, which now include catatonia.
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As NBD-Cl has not been reported as an allergen before, the characteristics of this chemical and its use as an analytical reagent are briefly surveyed.
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Immunoprecipitation analysis revealed a band with the molecular weight of the Band 3 anion channel only in the presence of the patient's serum and oxaliplatin.
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Five patients were treated with topical neomycin-polymyxin B-gramicidin (Neosporin) and propamidine isethionate (Brolene) drops.
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Protein in vitamin K absence (PIVKA) is the prothrombin precursor found in plasma when carboxylation to prothrombin is impaired.
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Mitral valve endocarditis resulting from coagulase-negative Staphylococcus after stent implantation in a saphenous vein graft.
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This case is the first report in which RLS augmentation is shown to be characterized by motor hyperkinesias paralleling levodopa plasma pharmacokinetic profile.
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We report a case of Thrombotic Thrombocytopenic Purpura occurring as an allergic response to trimethoprim-sulfamethoxazole therapy (Bactrim, Septra) in a Jehovah's Witness patient.
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During the following years, the patient was retested regularly.
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These enzymes may be associated with toxic reactions of differing frequency and severity.
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Less common adverse events to dapsone include the idiosyncratic reactions of leukopenia and agranulocytosis, cutaneous eruptions, peripheral neuropathy, psychosis, toxic hepatitis, cholestatic jaundice, nephrotic syndrome, renal papillary necrosis, severe hypoalbuminemia without proteinuria, an infectious mononucleosis-like syndrome, and minor neurological and gastrointestinal complaints.
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CASE REPORT: We hereby report a case of radiation recall dermatitis and myositis occurring on gemcitabine monotherapy, five months after completing chemoradiation for locally advanced pancreatic cancer.
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The role of antiemetics is invaluable in allowing cancer patients to complete, otherwise possibly intolerable, chemotherapy.
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The catheter had been in place for 28 months for administration of a 27 month course of intravenous cefotaxime for an unsubstantiated diagnosis of chronic Lyme disease.
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Patient 2 underwent two attempted operative anastamotic revisions with thrombectomies and local thrombolysis prior to CDT.
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Subsequently, five episodes of Wenckebach (Mobitz type 1) heart block with a ventricular rate of 28 beats/minute were observed on continuous cardiac telemetry.
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Electron microscopy revealed selective loss of myosin filaments in many fibers.
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She subsequently developed similar symptoms after multiple rechallenges with various loop diuretics including furosemide, bumetanide, and torsemide.
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It is of value in treating temper states in epilepsy and has the advantage of not causing extrapyramidal symptoms and side-effects are slight after the first week.
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The authors calculated that the blood lactate concentration could rise by 50% without requiring net lactic acid accumulation when the severe acidemia was corrected by alkali therapy.
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Before FAB therapy was started, the total serum DGTX concentration was 535 nmol/l.
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In some patients, this pH shift may be quite transient and temporary; whereas, in some patients with other maladies, the acidosis may be much more serious.
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Clinical consequences are discussed and disturbances of the blood brain barrier system as a speculative cause are hypothesized taking previous studies, animal studies and an additional reported clinical case into account.
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In the course of modifying her anticonvulsant regimen, the authors examined the 6beta-hydroxycortisol/cortisol ratio (6beta-OHF/F) in her urine, which can be the index of hepatic CYP3A4 activity, with electrospray ionization/mass spectrometry/mass spectrometry (ESI/MS/MS).
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Hemostasis was difficult to achieve, as the divided or disrupted amyloid-laden cortical vessels failed to vasoconstrict, their contractile elements replaced by amyloid beta protein.
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The clinical and histologic presentation of this side effect and possible biochemical mechanisms of pathogenesis are discussed.
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A 16-year-old poorly compliant, steroid-dependent subject with asthma received two courses of high-dose intravenous methylprednisolone during a 3-week period, followed by a tapering schedule of oral prednisone.
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Citalopram: an interaction study with clomipramine in a patient heterozygous for CYP2D6 genotype.
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We present a case report where switching from clozapine to quetiapine maintained the improvement in clinical status, after remittance of eosinophilia.
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Development of tics in a thirteen-year-old male following atomoxetine use.
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A 37-year-old female patient was diagnosed with ulcerative colitis 8 months ago and medical treatment with oral azathioprine, low-dose corticosteroids and 5-ASA was started.
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Severe apnea in an infant exposed to lamotrigine in breast milk.
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Despite vigorous therapy for the hyperthermia, he rapidly developed significant hypoxia requiring mechanical ventilation.
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These results suggest that the slowed clearance of cerivastatin in this patient might have been compounded by cytochrome P450, 2C8 dysfunction.
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Nitrofurantoin is commonly used to treat urinary tract infections during pregnancy.
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After 14 months of follow-up, the patient is well and free of disease.
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The postoperative course was uneventful and topical steroids were combined with neomycin and propamidine.
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Medicolegal problems in the management of cardiac arrhythmias in children.
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Hematological toxicity was moderate even at the 100 mg/m2 dose level.
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A case of severe acute hepatitis caused by cyproterone acetate in a 71 year old man with prostatic carcinoma is reported with a review of the literature on hepatic reactions to this drug.
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Coagulase-negative staphylococci were detected in cerebrospinal fluid (CSF), and the infection persisted even with intrathecal administration of gentamycin, and intravenous administration of vancomycin and arbekacin.
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Parameters of potassium, sodium, calcium, and phosphate metabolism as well as specific renal functions have been studied in the basal state and during administration of graded doses of phosphate (500-6000 mg).
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PURPOSE: Visually significant, pigmented cellular membranes may form on intraocular lenses after implantation.
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Interstitial pneumopathy and low-dosage amiodarone.
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Bisphosphonates in oral or intravenous forms are used to treat various diseases such as certain cancers, bone- and calcium-related disorders, osteoporosis, and osteopenia.
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The dog underwent multiple operations involving internal fixation of the fractured scapula with wire and a plate, followed by extensive chemotherapy with antibiotics and prednisolone.
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On visual field testing, a progressive evolution to a total and absolute central scotoma in the RE (central 10 degrees ) and an annular scotoma in the LE became apparent.
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Both patients recovered immediately without any signs of adverse effects and the two shunt systems have now been working properly for more than 36 and 21 months, respectively.
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A case of transient bullous dermolysis of the newborn associated with Wilms' tumor is reported.
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Asthmatic patients receive multiple drugs as part of their treatment program.
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Multiple stones and tumor cells infiltration were demonstrated in both kidney.
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We describe a patient with transitional cell carcinoma of the renal pelvis who developed respiratory dysfunction and an abnormal chest x-ray with diffuse interstitial opacities while on chemotherapy with piritrexim, a methotrexate analog.
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Development of neuroleptic malignant syndrome (NMS) following discontinuation of high-dose and high-potency neuroleptic agents is described.
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Barbiturates offer a mechanism of action that is different from that of benzodiazepines.
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Prolonged prostate-specific antigen response in flutamide withdrawal syndrome despite disease progression.
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Hydroxyurea (HU) and sodium phenylbutyrate (SPB) have been shown to increase fetal hemoglobin (Hb F) levels in patients with thalassemia intermedia.
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OBJECTIVE: To report on the possible development of serotonin syndrome in a patient receiving clomipramine after clozapine was withdrawn from the treatment regimen.
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We report a case of biopsy-proven acute tubulointerstitial nephritis associated with a second course of flurbiprofen, a nonsteroidal anti-inflammatory drug of the propionic acid class.
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Untreated tumors displayed continued growth.
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We report an unusually short lived and asymptomatic episode of severe cisplatin-induced renal tubular salt wasting in a fit 41-year-old patient with malignant teratoma.
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We described a patient who developed heart failure and pericarditis after bone marrow transplantation for a hematologic malignancy.
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METHODS: Single case report of failure of Baclofen pump investigated by radioisotope injection.
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Exposure to the individual compounds was determined by calculating the AUC.
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Transient decreases in hematocrit, complement components, and immunoglobulin concentrations occurred.
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Endoscopic injection of sclerosing agents is a strategy for control of esophageal varix bleeding.
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Significant clinical improvement of the porphyria followed withdrawal of the diphenylhydantoin.
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The progressive regression was remarkable.
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He underwent removal of the allograft and implantation of another liver.
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Sleep improvement in an insomniac patient with global pituitary insufficiency after change from triple to quadruple cortisol replacement therapy.
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His immune system at this time was almost completely depleted.
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Polyarthritis, hepatitis and anti-native DNA antibodies after treatment with ethambutol and rifampicin.
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Bortezomib is the first anticancer proteasome inhibitor introduced into clinical practice.
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Recurrent ischemic stroke involving an initially unaffected arterial territory during the course of thrombolysis has been reported but remains exceptionally rare.
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Genotyping prior to medication may be useful in evaluating patients with a high risk of severe systemic reaction to SASP.
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In this report, we suppose the possibility to develop a foetal malformations after a long-term wash out from isotretinoin therapy.
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Hydroxyurea and sodium phenylbutyrate therapy in thalassemia intermedia.
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A patient with a 30% scald burn was treated with topical silver sulfadiazine (Silvadene).
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RESULTS: There is no reliable and effective treatment of anterior ischemic optic neuropathy.
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Primary osteogenic sarcoma of the skull.
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RESULTS: A well-documented case report involving tap (draft) beer consumed while on an MAOI supports an earlier study, which recommended that all tap beers be restricted on MAOI diets.
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Reactivation of human herpesvirus-6 (HHV-6) is frequently observed, although the cause of DIHS is still unknown.
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Histologic examination showed in both cases epithelioid granulomas in close relation with scattered pigment.
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She developed a pre-engraftment immune reaction, which responded well to prednisolone, and engraftment was documented.
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Tc-99m labelled Anti CD 66 monoclonal antibody imaging is a useful, noninvasive approach to the assessment of bone marrow reserve under such circumstances.
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In addition to antimicrobial therapy, treatment usually involves craniotomy and excision of the abscess.
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Positive CSF PCR of JC virus confirmed the diagnosis.
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DISCUSSION: Amphotericin B deoxycholate has been reported to produce significant cardiac toxicity, with ventricular arrhythmias and bradycardia reported in overdoses in children and in adults with preexisting cardiac disease, even when administered in conventional dosages and infusion rates.
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Our literature review revealed an additional six cases of onset of inflammatory arthritis in MS patients receiving IFN-beta.
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Rare instances of autoimmune conditions have been observed in association with its use.
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